antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway
antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class Ib molecule in the ER. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.