antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent
antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway, tap-independent
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.