conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle
conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle
The process in which a discoidal high-density lipoprotein (HDL) particle acquires additional lipid or protein molecules, and cholesterol in the particle is converted to tightly bound cholesterol esters by the action of phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT), resulting in the formation of a spherical HDL particle.