transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
transcription-dependent tethering of rna polymerase ii gene dna at nuclear periphery
The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery. In S. cerevisiae, this process involves cis-acting DNA sequences such as the TATA box and upstream activating sequence (UAS) elements, trans-acting transcriptional activators, and also the 3'-UTR of the transcript.