RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
rna splicing, via transesterification reactions with bulged adenosine as nucleophile
Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure.