mucosal-associated invariant T cell, human
mucosal-associated invariant t cell, human
A mucosal-associated invariant T (MAIT) cell found in various tissues including human blood, liver, gut, and lung, characterised by a semi-invariant T cell receptor (TCR) comprising TRAV1-2 (Vα7.2) predominantly paired with TRAJ33, and high expression of CD161. Upon activation, MAIT cells produce inflammatory cytokines, including IFN-γ, TNF-α, and IL-17.