newly formed oligodendrocyte
newly formed oligodendrocyte
A post-mitotic oligodendrocyte that has exited the cell cycle and begun early stage differentiation. The cell begins to acquire oligodendrocyte-like characteristics but has not yet initiated myelination. In mice, NFOL is marked by the expression of Tcf7l2 and Cemip2 (also known as Tmem2), among other early myelin-related genes. These markers highlight cells transitioning from a precursor to a more differentiated, pre-myelinating state.