agouti-related protein expressing neuron
agouti-related protein expressing neuron
A GABAergic neuron located in the arcuate nucleus of the hypothalamus that expresses agouti-related protein (AgRP). This neuron can coexpress AgRP, GABA, and neuropeptide Y (NPY) in mice, and plays a key role in integrating metabolic signals. It is activated by hunger-related hormones such as ghrelin and inhibited by satiety signals like leptin.