type Ib group B Streptococcus capsular polysaccharide
type ib group b streptococcus capsular polysaccharide
A polysaccharide derivative that is the capsular polysaccharide of type Ib group B <em>Streptococcus</em>, consisting of saccharide chains involving α-<small>D</small>-NeuNAc-(2→3)-β-<small>D</small>-Gal<em>p</em>, β-<small>D</small>-Gal<em>p</em>-(1→3)-β-<small>D</small>-Glc<em>p</em>NAc, β-<small>D</small>-Glc<em>p</em>NAc-(1→3)-β-<small>D</small>-Gal<em>p</em>, β-<small>D</small>-Gal<em>p</em>-(1→4)-β-<small>D</small>-Glc<em>p</em> and β-<small>D</small>-Glc<em>p</em>-(1→4)-β-<small>D</small>-Gal<em>p</em> linkages. The whole can be conjugated to a carrier protein (<em>e.g.</em> CRM<small><sub>197</sub></small> and tetanus toxoid) randomly along the polysaccharide chain (cross-linked). An example structure is shown in the diagram.