camonsertib
camonsertib
A pyrazolopyridine that is 1<em>H</em>-pyrazolo[3,4-<em>b</em>]pyridine substituted by 1<em>H</em>-pyrazol-3-yl, (3-<i>endo</i>)-3-hydroxy-8-oxabicyclo[3.2.1]octan-3-yl, and (3<i>R</i>)-3-methylmorpholin-4-yl groups at positions 1, 4 and 6, respectively. It is a highly potent and selective inhibitor of ATR kinase (IC<small><sub>50</sub></small> = 1 nM).