granisetron
granisetron
A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 1-methyl-1<em>H</em>-indazole-3-carboxylic acid with the primary amino group of (3-<i>endo</i>)-9-methyl-9-azabicyclo[3.3.1]nonan-3-amine. A selective 5-HT<small><sub>3</sub></small> receptor antagonist, it is used (generally as the monohydrochloride salt) to manage nausea and vomiting caused by cancer chemotherapy and radiotherapy, and to prevent and treat postoperative nausea and vomiting.