neosartoricin
neosartoricin
A carbotricyclic compound obtained from the pathogenic fungi <em>Aspergillus fumigatus</em> and <em>Neosartorya fischeri</em> following activation of their polycyclic polyketide prenyltransferase (pcPTase)-containing silent clusters. It exhibits T-cell antiproliferative activity with an IC<small><sub>50</sub></small> of 3 μM, suggesting a possible physiological role as an immunosuppressive agent.