label: Barrett Adenocarcinoma
label_lc: barrett adenocarcinoma
description: An adenocarcinoma arising from Barrett metaplastic epithelium in the esophagus.  There is evidence supporting the idea that the Barrett adenocarcinomas develop through a stepwise progression through intestinal metaplastic epithelium to epithelial dysplasia to malignancy.  Adenocarcinomas arising in the setting of Barrett esophagus are typically papillary and/or tubular.  In terms of grading, they are well or moderately differentiated adenocarcinomas.