label: GM2 gangliosidosis, HEXB-related, domestic cat
label_lc: gm2 gangliosidosis, hexb-related, domestic cat
description: A lysosomal storage disease in cats due to a mutation in the HEXB gene. There is a buildup of GM2 gangliosides in tissues due to the lack of the enzyme hexosaminidase. Characterised by progressive neuromuscular dysfunction and impaired growth from an early age.