label: Vulvar Intraepithelial Neoplasia, HPV-Independent
label_lc: vulvar intraepithelial neoplasia, hpv-independent
description: HPV-negative vulvar squamous intraepithelial proliferation characterized by atypia of the basal and parabasal keratinocytes in an otherwise well-differentiated epithelium. Despite its subtle appearance, it has a high risk of malignant transformation. (WHO 2020)