label: DS Stage II Multiple Myeloma
label_lc: ds stage ii multiple myeloma
description: Multiple myeloma that fits in neither stage I nor stage III.  Estimated myeloma cell mass: 0.6 to 1.2 trillion (1012)/m2 (intermediate burden).  The following subclassification of stages is used: a. Creatinine less than 2.0 mg/dL, b. Creatinine greater than or equal to 2.0 mg/dL.  Impaired renal function worsens prognosis regardless of stage.  Note that the newer International Staging System defines stage II quite differently: Beta-2-microglobulin less than 3.5 and albumin less than 3.5 or beta-2-microglobulin 3.5 to less than 5.5 (median survival of 44 months).  (PDQ)