label: Immunodeficiency with Hyper-IgM Type 2
label_lc: immunodeficiency with hyper-igm type 2
description: An autosomal recessive immunodeficiency that is caused by mutation(s) in the AICDA gene, single-stranded DNA cytosine deaminase. It is characterized by normal or elevated concentrations of IgM and decreased or absent concentrations of IgG, IgA, and IgE.