label: Primary Cutaneous CD4-Positive Small/Medium T-Cell Lymphoproliferative Disorder
label_lc: primary cutaneous cd4-positive small/medium t-cell lymphoproliferative disorder
description: A primary cutaneous T-cell lymphoproliferative disorder composed of small to medium-sized CD4-positive, CD8-negative, and CD30-negative pleomorphic T-lymphocytes in the dermis. A small number of large pleomorphic T-lymphocytes, focal epidermotropism, and subcutaneous involvement may be seen. It usually presents with a solitary plaque or tumor on the face, neck, or upper trunk. The clinical behavior is almost always indolent, and most patients present with localized disease.