label: Reduced circulating 5-oxoprolinase activity
label_lc: reduced circulating 5-oxoprolinase activity
description: Activity or concentration of 5-oxoprolinase in the blood circulation below the lower limit of normal. This enzyme catalyzes the reaction 5-oxo-L-proline + ATP + 2 H(2)O = L-glutamate + ADP + 2 H(+) + phosphate.