label: microcephalic osteodysplastic primordial dwarfism type II
label_lc: microcephalic osteodysplastic primordial dwarfism type ii
description: A form of microcephalic primordial dwarfism (MPD) characterized by severe pre- and postnatal growth retardation, with marked microcephaly in proportion to body size, skeletal dysplasia, abnormal dentition, insulin resistance, and increased risk for cerebrovascular disease.