label: CHEK2-Associated Li-Fraumeni-Like Syndrome
label_lc: chek2-associated li-fraumeni-like syndrome
description: An autosomal dominant cancer predisposition syndrome caused by germline mutations of the CHEK2 gene. It is associated with breast carcinoma, gastric carcinoma, colorectal carcinoma, thyroid gland carcinoma, kidney carcinoma, prostate carcinoma, and non-Hodgkin lymphoma.