label: Autosomal Recessive Cerebral Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
label_lc: autosomal recessive cerebral arteriopathy with subcortical infarcts and leukoencephalopathy
description: An autosomal recessive condition caused by mutation(s) in the HTRA1 gene, encoding serine protease HTRA1. It is characterized by subcortical infarcts and leukoencephalopathy resulting in progressive motor dysfunction and dementia.