label: Pituitary Gland Blastoma
label_lc: pituitary gland blastoma
description: A rare developmental early childhood neoplasm, arising within the fetal anterior pituitary. It is associated with DICER1 mutations. Patients present with features of Cushing disease, with elevated blood ACTH levels and hypercortisolism. Ophthalmoplegia is a frequent symptom. The overall prognosis is poor. (WHO)