label: Colorectal Large Cell Neuroendocrine Carcinoma
label_lc: colorectal large cell neuroendocrine carcinoma
description: An aggressive high-grade carcinoma with neuroendocrine differentiation that arises from the colon or rectum and is composed of malignant large cells. The mitotic count is more than 20 per 2 mm2 and/or the Ki-67 index is more than 20%.