label: IL10-related early-onset inflammatory bowel disease
label_lc: il10-related early-onset inflammatory bowel disease
description: A rare immune dysregulation disease with immunodeficiency characterized by severe, progressive infantile onset inflammatory bowel disease with pancolitis, perianal disease (ulceration, fistulae), recurrent respiratory, genitourinary and cutaneous infections, arthritis and a high risk of B-cell lymphoma.