label: HHV8-Positive Germinotropic Lymphoproliferative Disorder
label_lc: hhv8-positive germinotropic lymphoproliferative disorder
description: A monotypic HHV8-positive lymphoproliferative disorder that usually occurs in HIV-negative individuals. It is characterized by the presence of HHV8-positive plasmablasts partially or completely replacing germinal centers. Coinfection with EBV is characteristic. In most cases, there is a favorable response to chemotherapy or radiation. (WHO 2017)