label: recurrent infections associated with rare immunoglobulin isotypes deficiency
label_lc: recurrent infections associated with rare immunoglobulin isotypes deficiency
description: Deficiencies in immunoglobulin (Ig) isotypes (including: isolated IgG subclass deficiency, IgG subclass deficiency with IgA deficiency and kappa chain deficiency) are primary immunodeficiencies that are often asymptomatic but can be characterized by recurrent, often pyogenic, sinopulmonary infections.