label: combined immunodeficiency due to ZAP70 deficiency
label_lc: combined immunodeficiency due to zap70 deficiency
description: Combined immunodeficiency due to ZAP70 deficiency is a very rare, severe, genetic, combined immunodeficiency disorder characterized by lymphocytosis, decreased peripheral CD8+ T-cells, and presence of normal circulating CD4+ T-cells, leading to immune dysfunction.