label: early-onset pulmonary and cutaneous vasculitis
label_lc: early-onset pulmonary and cutaneous vasculitis
description: A monogenic autoinflammatory disorder caused by a de novo activating mutation, p.Tyr515∗, in hematopoietic cell kinase (HCK). The disease is characterized by cutaneous vasculitis and chronic pulmonary inflammation that progresses to fibrosis.