label: Susceptibility to Multiple System Atrophy-1
label_lc: susceptibility to multiple system atrophy-1
description: A heritable condition caused by mutation(s) in the COQ2 gene encoding 4-hydroxybenzoate polyprenyltransferase, mitochondrial. It is a progressive neurodegenerative disorder affecting both the central and peripheral nervous system. It is clinically and pathologically similar to Lewy body dementia and Parkinson disease.