label: Pulmonary Lymphomatoid Granulomatosis
label_lc: pulmonary lymphomatoid granulomatosis
description: A rare lymphoproliferative disorder that affects the lungs.  It is characterized by the presence of an angiocentric and angiodestructive polymorphic cellular infiltrate composed of EBV-positive neoplastic B-lymphocytes and reactive T-lymphocytes.  The majority of patients present with bilateral nodular lesions in the lungs.  The prognosis depends on the histologic grade of the lesions. One third of patients with grade 1 lesions and two thirds of patients with grade 2 lesions progress to non-Hodgkin lymphoma.  Grade 3 lesions, by definition, are classified as non-Hodgkin lymphomas.