label: Acute Myeloid Leukemia with inv(3) (q21.3;q26.2); GATA2, MECOM
label_lc: acute myeloid leukemia with inv(3) (q21.3;q26.2); gata2, mecom
description: An acute myeloid leukemia associated with inv(3)(q21.3q26.2) resulting in the reposition of a distal GATA2 enhancer to activate MECOM expression. It may present de novo or follow a myelodysplastic syndrome. The clinical course is aggressive.