label: Buerger Disease
label_lc: buerger disease
description: An inflammatory vascular disorder that affects small and medium-sized arteries and veins in the extremities. The inflammatory process is initiated in the tunica intima and results in thrombosis and vascular obstruction with subsequent ischemia and ulceration of the limbs and digits. It affects males more often than females and usually occurs at age 20-45 years.  It is strongly associated with heavy tobacco use.