label: BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome
label_lc: brca1/2-associated hereditary breast and ovarian cancer syndrome
description: An autosomal dominant inherited syndrome caused by deleterious mutations in the BRCA1 or BRCA2 genes. Patients are at high risk of developing breast cancer, particularly before the age of fifty, high risk of developing a second primary breast cancer, and high risk of developing both breast and ovarian cancer.