Ethanolamine kinase family
ethanolamine kinase family
The ethanolamine kinases, and closely related choline kinases, catalyze the first step of the Kennedy pathway, which is the ATP-dependent phosphorylation of ethanolamine or choline, forming PE or PC, respectively, and the byproduct ADP. Mammalian cells carry two ethanolamine-specific kinases: ETNK1 and ETNK2 that have negligible choline kinase activity.