Transcription factor Dp family
transcription factor dp family
In molecular biology, transcription factor DP is a family of proteins which function as transcription factors. DP forms a heterodimer with E2F and regulates genes involved in cell cycle progression. The transcriptional activity of E2F is inhibited by the retinoblastoma protein which binds to the E2F-DP heterodimer [1] and negatively regulates the G1-S transition.