Acetyl-CoA carboxylase family
acetyl-coa carboxylase family
Acetyl-coenzyme A carboxylases (commonly called ACCs) have crucial roles in fatty acid metabolism in most living organisms. Acetyl-coenzyme A carboxylase is a biotin-dependent enzyme and catalyzes the carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic activities, biotin carboxylase (BC) and carboxyltransferase (CT). It is a multi-subunit enzyme in most prokaryotes, whereas it is a large, multi-domain enzyme in most eukaryotes.