Creatine kinase family
creatine kinase family
The enzyme creatine kinase catalyses the reversible transfer of a phosphoryl group from ATP to creatine. There are four distinct creatine kinase isoforms — two cytosolic isoforms (CKM and CKB) and two mitochondrial isoforms (CKMT1 and CKMT2) — all of which are encoded by different genes. The tandemly duplicated genes CKMT1A and CKMT1B encode identical CKMT1 proteins.