Lysophospholipid acyltransferases
lysophospholipid acyltransferases
Phospholipids can be produced by several metabolic routes, and a key reaction that utilizes lysophospholipids and acyl-CoAs as substrates to produce phospholipids is catalyzed by a class of enzymes called lysophospholipid acyltransferases (LPLATs). Based on their primary structures, these LPLATs are divided into two families, the 1-acylglycerol-3-phosphate O-acyltransferase (AGPAT) and the membrane bound O-acyltransferase (MBOAT) families. These two families also contain non-LPLAT members.