Gamma-aminobutyric acid type B receptor subunits
gamma-aminobutyric acid type b receptor subunits
GABA B receptors (GABA BR) are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA) that are linked via G-proteins to potassium channels. The changing potassium concentrations hyperpolarize the cell at the end of an action potential. The reversal potential the GABA B-mediated IPSP is -100 mV, which is much more hyperpolarized than the GABA A IPSP. GABA B receptors are found in the central and peripheral autonomic nervous system.