Cadherin related
cadherin related
The cadherin-related (CDHR) genes do not fit into the major cadherin or protocadherin families as they are phylogenetically clearly separated. The encoded proteins comprise at least two typical, consecutive cadherin motifs, but often more than the typical members of the cadherin and protocadherin families. Their overall domain organization differs from the members of the major cadherin family and the protocadherin family, and includes different and unique cytoplasmic domains.