U5 small nuclear ribonucleoprotein
u5 small nuclear ribonucleoprotein
The U5 snRNP complex is involved in pre-mRNA splicing events. Of the six U5 snRNP-specific proteins, three are NTPases. DDX23 and SNRNP200 are members of the DEXD/H box family and EFTUD2 is the sole GTPase identified in the spliceosome to date. The NTPases of the U5 snRNP are involved in the critical switch in which U1 is replaced by U6 at the 5 prime splice site.