NoRC complex
norc complex
NoRC remodels nucleosomes at the rDNA promoter and recruits histone deacetylases, histone methyltransferase and DNA methyltransferases leading to heterochromatin formation and transcriptional silencing. The interaction of NoRC with the short RNA transcripts is mediated by the TAM domain of BAZ2A and it is required for NoRC binding to chromatin and heterochromatin formation.