Glutathione peroxidase family
glutathione peroxidase family
Glutathione peroxidases are enzymes that catalyse the reduction of H2O2 or organic hydroperoxides to water or the corresponding alcohols, typically in a glutathione-dependent manner. Five family members (GPX1-4, GPX6) are selenoproteins with a selenocysteine residue at the active site while the other three (GPX5, 7-8) have a cysteine residue at the active site.