Zinc fingers ZZ-type
zinc fingers zz-type
In molecular biology the ZZ-type zinc finger domain is a type of protein domain that was named because of its ability to bind two z inc ions. These domains contain 4-6 Cys residues that participate in zinc binding (plus additional Ser/His residues), including a Cys-X2-Cys motif found in other zinc finger domains. These zinc fingers are thought to be involved in protein-protein interactions. The structure of the ZZ domain shows that it belongs to the family of cross-brace zinc finger motifs that include the PHD, RING, and FYVE domains.