Polypeptide N-acetylgalactosaminyltransferases
polypeptide n-acetylgalactosaminyltransferases
In enzymology, a polypeptide N-acetylgalactosaminyltransferase ( EC 2.4.1.41 ) is an enzyme that catalyzes the chemical reaction   UDP-N-acetyl-D-galactosamine + polypeptide UDP + N-acetyl-D-galactosaminyl-polypeptide   Thus, the two substrates of this enzyme are UDP-N-acetyl-D-galactosamine and polypeptide, whereas its two products are UDP and N-acetyl-D-galactosaminyl-polypeptide.  This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. This enzyme participates in o-glycan biosynthesis and glycan structures - biosynthesis 1. It has 2 cofactors : manganese, and calcium.