F-BAR domain containing
f-bar domain containing
The F-BAR domain, also known as the extended FCH domain (EFC) in PCH family proteins includes the FCH domain and CC region and is only weakly similar to the BAR domain. By sequence alignment, structural, biochemical and cell biological studies, it has been shown that the EFC is actually an extended BAR domain, and that F-BAR domains share similar properties with BAR domains. The F-BAR domain plays a role in dimerization and membrane phospholipid binding.