eNoSC complex
enosc complex
Glucose deprivation reduces rRNA synthesis. An energy-dependent change in the NAD+/NADH ratio regulates the eNoSC complex, allowing it to couple the changing energy status with the level of rRNA transcription by regulating the epigenetic status of rRNA clusters. eNoSC promotes the restoration of energy balance and protects cells from energy deprivation-induced apoptosis.