STK38/LATS kinase family
stk38/lats kinase family
The STK38/LATS family of kinases is a subclass of the AGC group of serine/threonine protein kinases. Members of the STK38/LATS family are vital components of conserved pathways controlling essential cellular processes, such as proliferation (cell cycle progression) and cell death. Notably, all STK38/LATS kinases share two unique characteristics, a conserved N-terminal regulatory domain (NTR) in proximity to the catalytic domain and an insertion between subdomains VII and VIII of the catalytic domain.