Transcription and export complex 1 subunits
transcription and export complex 1 subunits
The TREX complex couples transcription elongation by RNA polymerase II to mRNA export, moving along the gene with the elongating polymerase during transcription. It acts as a binding platform for the protein product of NXF1 (nuclear RNA export factor 1). TREX subunits are also involved in piRNA transcription and biogenesis. The TREX complex also helps prevent R-loop formation during transcription.