Endocannabinoid hydrolases
endocannabinoid hydrolases
The endocannabinoid system (ECS) defines two types of endogenous agonist: esters and amides of fatty acids. The esters and amides are synthesised by two independent enzyme systems; separate hydrolases also terminate their action. The functions of these endocannabinoids are primarily mediated through two G protein-coupled receptors (encoded by CNR1 and CNR2).