Glutamic--pyruvic transaminase family
glutamic--pyruvic transaminase family
Glutamic--pyruvic transaminase (also known as alanine aminotransferase) catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate, playing a key role in the intermediary metabolism of glucose and amino acids. There are two isoforms in human encoded by GPT and GPT2 that show differential expression and subcellular localisation.