name: S-[(2R)-succino]-L-cysteine + O2 <=> S-[(2R)-succino]-(hydroxyimino)ethanethiol + CO2 + H2O


name: scyllo-inositol(out) + 2 Na(+)(out) = scyllo-inositol(in) + 2 Na(+)(in)


name: (R)-glycerate + NAD(+) = 3-hydroxypyruvate + NADH + H(+)


name: CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK binds CBL (Homo sapiens)


name: a (2R)-2-hydroxycarboxylate + A <=> a 2-oxocarboxylate + AH2


name: deoxyribonucleoside diphosphate metabolic process


name: 4alpha-carboxy-4beta-methyl-5alpha-cholest-7-ene-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O => 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol + 6 Fe(II)-[cytochrome b5] + 3 O2 + 5 H(+)


name: FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)


name: TRADD:TRAF2:RIP1 binds FADD (Sus scrofa)


name: S1P hydrolyzes SREBP1A,1C,2 (Mus musculus)


name: Kinetochore assembly (Xenopus tropicalis)


name: eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Bos taurus)


name: Inactive RAFs bind YWHAB (Drosophila melanogaster)


name: PC is hydrolysed to 2-acyl LPC by PLA2[7] (Saccharomyces cerevisiae)


name: Localization of CBL:GRB2 to the membrane (Mus musculus)


name: Abortive Initiation Before Second Transition (Canis familiaris)


name: L-asparaginyl-tRNA(Asn) + phosphate + H(+) => 4-phosphooxy-L-aspartyl-tRNA(Asn) + NH4(+)


name: kainate(in) + ATP + H2O <=> kainate(out) + ADP + phosphate + H(+)


name: chenodeoxycholoyl-CoA + taurine <=> taurochenodeoxycholate + CoA + H(+)


name: EXT1:EXT2 transfers GlcNAc to the heparan chain (Drosophila melanogaster)


name: ATXN3 family cleave Ub chains (Dictyostelium discoideum)


name: N-tetradecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = N-tetradecanoylethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 => (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate


name: Passive I- efflux mediated by SLC5A8 (Mus musculus)


name: Formation of Pol zeta complex (Homo sapiens)


name: L-methionyl-[protein] + [thioredoxin]-disulfide + H2O <=> L-methionyl-(R)-S-oxide-[protein] + [thioredoxin]-dithiol


name: LONP1 binds mitochondrial matrix proteins (Homo sapiens)


name: 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid (Mus musculus)


name: AKT binds PDPK1 (Saccharomyces cerevisiae)


name: Active FLT3 binds to ABL2 (Canis familiaris)


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Mus musculus)


name: Activated FGFR1 phosphorylates SHC1 (Drosophila melanogaster)


name: Phosphorylation of HSF1 at Ser326 induces transactivation (Schizosaccharomyces pombe)


name: p-EFNB binds GRB4 (Caenorhabditis elegans)


name: beta-galactosidase activity (lactose isomerization)


name: a 2'-deoxycytidine in single-stranded DNA + glyoxal + succinate + CO2 => a 3,N(4)-etheno-2'-deoxycytidine in single-stranded DNA + 2-oxoglutarate + O2 + H2O


name: (9Z)-tetradecenoyl-CoA + H2O <=> (9Z)-tetradecenoate + CoA + H(+)


name: "Thioether and trialkylsulfonium hydrolases"


name: a 2-hydroxy carboxylate + O2 <=> a 2-oxocarboxylate + H2O2


name: WLS:WNT complex is internalized for maturation into exosomes (Bos taurus)


name: 4alpha-formyl-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + H(+) => 4alpha-carboxy-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: methanethiol + S-adenosyl-L-methionine <=> dimethyl sulfide + S-adenosyl-L-homocysteine + H(+)


name: LIFR:JAKs bind gp130:JAKs:CNTFR (Canis familiaris)


name: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate (Homo sapiens)


name: MAD2 associates with the Mad1 kinetochore complex (Homo sapiens)


name: COASY phosphorylates DP-CoA (Saccharomyces cerevisiae)


name: Caspase-mediated cleavage of vimentin at DSVD (85) (Sus scrofa)


name: SUMOylation of AURKA with SUMO1 (Homo sapiens)


name: GRB2-1:SOS1 binds p-3Y-SHC1 (Mus musculus)


name: a medium-chain fatty acyl-AMP + diphosphate => a medium-chain fatty acid + ATP + H(+)


name: SMAD2/3 activation induces binding of RNF111/SMURF2 to SKI/SKIL (Homo sapiens)


name: N-terminal N-methyl-L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine => N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)


name: a (4E,8E)-4-sphinga-4,8-dienine ceramide + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an N-acyl-(4E,8E,10E)-sphingatrienine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 1,3-dinitroglycerol + NADPH <=> 1-nitroglycerol + nitrite + NADP(+)


name: 16S rRNA (guanine(966)-N(2))-methyltransferase activity


name: aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Mus musculus)


name: Prolactin receptor ligands bind the prolactin receptor (Homo sapiens)


name: SLC7A8-mediated uptake of neutral amino acids (Bos taurus)


name: atrochrysone carboxylate + holo-[ACP] + H(+) => atrochrysone carboxyl-[ACP] + H2O


name: 11-dehydrocorticosterone + NADH + H(+) => corticosterone + NAD(+)


name: sequestered tissue factor -> tissue factor (Rattus norvegicus)


name: dibenzothiophene + 2 FMNH2 + 2 O2 <=> dibenzothiophene 5,5-dioxide + 2 FMN + 2 H2O + 2 H(+)


name: BTRC binds p-S344, 347 NFE2L2 (Bos taurus)


name: 3 propionate 3-nitronate + 3 O2 + H2O => 3 3-oxopropanoate + 2 nitrate + nitrite + H2O2 + 3 H(+)


name: (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + phosphate + 2 H(+) => 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP


name: Interaction of Tie2 with Ang1 (Danio rerio)


name: Binding of IRS to insulin receptor (Canis familiaris)


name: Deacetylation of cohesin (Canis familiaris)


name: activation of production of molecular mediator of immune response


name: 3-oxo-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + CO2 + CoA => (9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + malonyl-CoA + H(+)


name: vasoactive intestinal polypeptide receptor binding


name: LTN1 K48 polyubiquitinates the nascent peptide in NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide (Caenorhabditis elegans)


name: Cross-linking of FCGRIIIA with IgG-coated Ag (Sus scrofa)


name: alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ (Drosophila melanogaster)


name: 14-3-3 Binds p-S237-TBC1D1 (Homo sapiens)


name: a globoside MSGG (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a globoside DSGG (d18:1(4E)) + CMP + H(+)


name: GREB1 binds ESR1:ESTG and co-activators (Mus musculus)


name: Translesion synthesis across unhooked ICL by POLN (Mus musculus)


name: Fillagrin and keratin intermediate filaments polymerize forming a network (Canis familiaris)


name: GRB2:SOS:p-Y427-SHC1 mediated nucleotide exchange of RAS (Homo sapiens)


name: [thioredoxin]-disulfide + L-methionine + H2O = L-methionine (R)-S-oxide + [thioredoxin]-dithiol


name: D-proline(out) + H(+)(out) = D-proline(in) + H(+)(in)


name: DAG is hydrolyzed to 2-MAG by PNPLA2/3 (Danio rerio)


name: ATG7:ATG3:LC3 dissociates (Mus musculus)


name: N-(9Z-octadecanoyl)-dopamine + CoA + H(+) => dopamine + (9Z)-octadecenoyl-CoA


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 13(S)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Active LTK receptor binds SHC1 (Mus musculus)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Gallus gallus)


name: 1-acyl LPC is acylated to PC by LPCAT (Homo sapiens)


name: lanosterol + hexadecanoate + H(+) => lanosteryl hexadecanoate + H2O


name: Recruitment of HDAC1 by p107 (RBL1) (Gallus gallus)


name: Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 (Rattus norvegicus)


name: WIP binds WASP,N-WASP, activating them (Homo sapiens)


name: 4-(2-aminophenyl)-2,4-dioxobutanoate + L-tyrosine => 3-(4-hydroxyphenyl)pyruvate + L-kynurenine


name: propanoyl-CoA + formate => 2-oxobutanoate + CoA


name: D-apiitol + NAD(+) <=> aldehydo-D-apiose + NADH + H(+)


name: PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Plasmodium falciparum)


name: Association of Emi1 with Cdh1 (Rattus norvegicus)


name: Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)


name: EP300,CREBBP bind SOH-C481-FOXO4 (Homo sapiens)


name: Activated FGFR1 binds FLRT1,2,3 (Gallus gallus)


name: Active ALK phosphorylates PLCG1 (Bos taurus)


name: (2E,6E)-farnesol + NADPH + O2 + H(+) = (2E,6E)-omega-hydroxy-farnesol + NADP(+) + H2O


name: negative regulation of RNA catabolic process


name: L-serine + hexadecanoyl-CoA + H(+) = 3-oxosphinganine + CO2 + CoA


name: ITPA dimer dephosphorylates RBV-TP to RBV-MP (Homo sapiens)


name: RUNX1 and GATA1 bind the promoter of the GP1BA gene (Homo sapiens)


name: SPZ dimer bound TL dimerises at the plasma membrane (Drosophila melanogaster)


name: Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Caenorhabditis elegans)


name: Formation of Elongin BC complex (Rattus norvegicus)


name: KSRP recruits RNA degradation activities (Sus scrofa)


name: Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus (Saccharomyces cerevisiae)


name: 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by PTGR1 (Homo sapiens)


name: DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Canis familiaris)


name: FUNDC1 is phosphorylated by CK2 (Sus scrofa)


name: 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH (Danio rerio)


name: AMBRA1:DYNLL1,DYNLL2 binds BECN1 complex (Mus musculus)


name: SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Mus musculus)


name: Phosphorylation of Cyclin E:CDK2 complexes by WEE1 (Drosophila melanogaster)


name: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O2 => 2 vanillin


name: EP300 acetylates RUNX3 (Canis familiaris)


name: (E)-(indol-3-yl)acetaldehyde oxime + reduced [NADPH--hemoprotein reductase] + O2 => 1-aci-nitro-2-(1H-indol-3-yl)ethane + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: AKT phosphorylates FOXO transcription factors (Caenorhabditis elegans)


name: decanoyl-CoA + malonyl-[ACP] + H(+) <=> 3-oxododecanoyl-[ACP] + CO2 + CoA


name: STAT4 binds IL12RB2:IL12RB2 (Mus musculus)


name: Activated MAPKs phosphorylate BRAF (Drosophila melanogaster)


name: IDUA cleaves iduronate from HS chain (Canis familiaris)


name: Phosphorylation of Cx43 by c-src (Sus scrofa)


name: TRIM21 ubiquitinates SQSTM1 (Caenorhabditis elegans)


name: carbofuran + H2O + H(+) => 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol + methylamine + CO2


name: PC is hydrolyzed to 1-acyl LPC by PLA2[5] (Homo sapiens)


name: Active ARF recruits coatomer (Plasmodium falciparum)


name: HSBP1 binds HSF1 trimer (Canis familiaris)


name: Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex (Gallus gallus)


name: 3'-dephospho-CoA + diphosphate => (R)-4'-phosphopantetheine + ATP + H(+)


name: holo-[ACP] + adenosine 3',5'-bisphosphate + H(+) => apo-[ACP] + CoA


name: NADH dehydrogenase (ubiquinone) activity


name: 24-methylidenelophenol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => 4alpha-hydroxymethyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: PXYLP1 dephosphorylates Xyl moiety (Bos taurus)


name: LRAT esterifies RBP2:atROL and FACYLs to atREs (Mus musculus)


name: Activated protein C cleaves factor Va to factor Vi intermediate form (Canis familiaris)


name: HCMV Genome Replication Completion (Homo sapiens)


name: D-arabinitol 1-phosphate + NAD(+) => D-xylulose 5-phosphate + NADH + H(+)


name: (21S)-21-acetyl-1-hydroxy-apo-melianone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => (21S)-21-acetoxyl-apo-melianone + reduced [NADPH--hemoprotein reductase] + O2


name: creatine(out) + chloride(out) + 2 Na(+)(out) => creatine(in) + chloride(in) + 2 Na(+)(in)


name: L-glutamyl-tRNA(Gln) + ATP => 5-phosphooxy-L-glutamyl-tRNA(Gln) + ADP


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Bos taurus)


name: D-alanine + A + H2O => pyruvate + AH2 + NH4(+)


name: Translocation of ERBB4s80:YAP1 complex to the nucleus (Homo sapiens)


name: Fibrillin 1, 2,(3) degradation by MMP2, 9, 12 and 13 (Mus musculus)


name: lipid IIA + a 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine = lipid IIB + a 2-acyl-sn-glycero-3-phosphocholine


name: p-S167-ESR1 activates expression of HTRA2 (OMI) (Homo sapiens)


name: 3,3'-diiodo-L-thyronine + iodide + A + H(+) => 3,3',5'-triiodo-L-thyronine + AH2


name: Synthesis of minus strand strong stop DNA (-sssDNA) (Homo sapiens)


name: 3,3'-diiodothyronamine + iodide + A + H(+) = 3,3',5-triiodothyronamine + AH2


name: D-glyceraldehyde 3-phosphate + pyruvate => 2-dehydro-3-deoxy-6-phospho-D-gluconate


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Plasmodium falciparum)


name: NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN (Rattus norvegicus)


name: 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + ATP + CoA <=> 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoyl-CoA + AMP + diphosphate


name: S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA + AH2 + ATP => 2-thiouridine(34) in tRNA + L-cysteinyl-[protein] + A + AMP + diphosphate + H(+)


name: (S)-4-hydroxy-2-oxopentanoate = (2Z)-2-hydroxypenta-2,4-dienoate + H2O


name: SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix (Xenopus tropicalis)


name: O-acetylandilesin A => andilesin B + acetate + H(+)


name: formate + CoA + H(+) => formyl-CoA + H2O


name: S-sulfosulfanyl-L-cysteinyl-[SoxY protein] + 2 Fe(II)-[cytochrome c] + 2 H(+) => L-cysteinyl-[SoxY protein] + thiosulfate + 2 Fe(III)-[cytochrome c]


name: L-valine(in) + H(+)(out) = L-valine(out) + H(+)(in)


name: hexanal + NADP(+) => (E)-hex-2-enal + NADPH + H(+)


name: METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Gallus gallus)


name: KAT5 acetylates ATM at shortened telomeres (Gallus gallus)


name: beta-nicotinamide D-ribonucleotide + H2O = nicotinate beta-D-ribonucleotide + NH4(+)


name: N-tetracosanoylsphinganine + NADPH + O2 + H(+) => N-(2-hydroxytetracosanoyl)-sphinganine + NADP(+) + H2O


name: COPRS binds CCND1:CDK4:PRMT5:pT5-WDR77 (Canis familiaris)


name: IER3 recruits MAPKs to PP2A-B56-beta,gamma (Canis familiaris)


name: HSF1 is activated by phosphorylation, translocation to the nucleus, and trimerization (Dictyostelium discoideum)


name: 5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Canis familiaris)


name: I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol (Mus musculus)


name: ENPP7 hydrolyzes sphingomyelin (Saccharomyces cerevisiae)


name: Thrombin-activated PARs binds G-protein Gq (Xenopus tropicalis)


name: UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose + UDP + H(+)


name: malonate(in) + 2-oxoglutarate(out) <=> malonate(out) + 2-oxoglutarate(in)


name: methyl-Co(III)-[dimethylamine-specific corrinoid protein] + methylamine => Co(I)-[dimethylamine-specific corrinoid protein] + dimethylamine + H(+)


name: N(4)-benzoylagmatine + H2O => agmatine + benzoate


name: a 3-O-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + UDP + H(+)


name: SUMOylation of TFAP2A with SUMO1 (Homo sapiens)


name: 2,3-epoxyphylloquinone + [protein]-dithiol => phylloquinone + [protein]-disulfide + H2O


name: W-molybdopterin cofactor catabolic process


name: STAT3,STAT6 bind p-Y-IL4R (Mus musculus)


name: IL12RB1:TYK2 binds IL12RB2:JAK2 (Bos taurus)


name: SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB (Bos taurus)


name: STUB1 ubiquitinates RIPK1 at K571, K604, K627 (Bos taurus)


name: Formation of the 19S regulatory particle lid (Drosophila melanogaster)


name: ALDH3B2 oxidises HXAL to PALM (Drosophila melanogaster)


name: ZnT5 transports zinc into secretory granules in pancreatic beta cells (Xenopus tropicalis)


name: 14,15-dihydroxy-(5Z,8Z,11Z)-eicosatrienoate => 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H2O


name: Tyrosine phosphorylated IL6ST binds STAT1,STAT3 (Homo sapiens)


name: NPAS4 binds PLK2 gene promoter (Homo sapiens)


name: Formation of peptide loading complex (PLC) (Mus musculus)


name: aralkylamine dehydrogenase (azurin) activity


name: (2E,6E)-farnesyl diphosphate + H2O => (+)-isoafricanol + diphosphate


name: glutaryl-CoA + malonyl-[ACP] + H(+) = 3-oxo-6-carboxyhexanoyl-[ACP] + CO2 + CoA


name: MigFilin associates with Filamin and F-actin (Xenopus tropicalis)


name: LPIN1 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex (Homo sapiens)


name: salicin + UDP + H(+) => salicyl alcohol + UDP-alpha-D-glucose


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine


name: ent-copalyl diphosphate = ent-isokaurene + diphosphate


name: SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol (Caenorhabditis elegans)


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Canis familiaris)


name: 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) <=> 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Squalene 2,3-epoxide cyclizes, forming lanosterol (Xenopus tropicalis)


name: glutathione disulfide + H2O2 => 2 glutathione + O2


name: Phosphorylated SMAD2/3 dissociates from TGFBR (Danio rerio)


name: SREBP1A,1C binds the FASN promoter (Homo sapiens)


name: oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor


name: "With an iron-sulfur protein as acceptor"


name: ESPL1 (Separase) cleaves centromeric cohesin (Gallus gallus)


name: Gbeta:gamma activation of PLC beta (Mus musculus)


name: N(6)-methyl-L-lysyl-[protein] + A + H2O <=> L-lysyl-[protein] + formaldehyde + AH2


name: (2S)-lactyl-2-diphospho-5'-guanosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin => oxidized coenzyme F420-0 + GMP + H(+)


name: D-tryptophan(out) + chloride(out) + 2 Na(+)(out) <=> D-tryptophan(in) + chloride(in) + 2 Na(+)(in)


name: a menaquinol + sulfate => a menaquinone + sulfite + H2O


name: alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose => beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + UDP + H(+)


name: BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 (Homo sapiens)


name: octacosanoyl-CoA + 2 NADPH + 2 H(+) <=> octacosan-1-ol + 2 NADP(+) + CoA


name: isoproturon + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) <=> 1-methyl-3-[4-(propan-2-yl)phenyl]urea + formaldehyde + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane (Mus musculus)


name: SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol (Rattus norvegicus)


name: Defective IDUA does not hydrolyse Heparan sulfate chain(6) (Homo sapiens)


name: MARK3 phosphorylates MITF-M on S173 (Xenopus tropicalis)


name: RHOU binds effectors at the plasma membrane (Drosophila melanogaster)


name: CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Bos taurus)


name: nicotinamide + S-adenosyl-L-methionine => 1-methylnicotinamide + S-adenosyl-L-homocysteine


name: STAT1 stimulates SMAD7 gene transcription (Homo sapiens)


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 (Schizosaccharomyces pombe)


name: Arachidonate is oxidised to PGG2 by PTGS1 (Xenopus tropicalis)


name: Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Schizosaccharomyces pombe)


name: 3-hydroxypyruvate + H2O2 + NH4(+) => L-serine + O2 + H2O


name: 3-methylbutanol + NAD(+) => 3-methylbutanal + NADH + H(+)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O <=> 1-hexadecanoyl-sn-glycero-3-phosphate + (9Z)-octadecenoate + H(+)


name: Aldolase tetramers convert GA3P and DHAP to F1,6PP (Canis familiaris)


name: 5-hydroxymethyl-dCDP + ADP => 5-hydroxymethyl-dCMP + ATP


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA => 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: diacetylchitobiose-6'-phosphate + H2O => N'-monoacetylchitobiose-6'-phosphate + acetate


name: Caspase-6 translocates to the nucleus (Mus musculus)


name: RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Rattus norvegicus)


name: 3,20-dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene + 2 S-adenosyl-L-homocysteine + 2 H(+) => C30 botryococcene + 2 S-adenosyl-L-methionine


name: TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 (Bos taurus)


name: AVPR1A,2 bind AVPR antagonists (Bos taurus)


name: 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Canis familiaris)


name: 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: UTP + GTP <=> 3',3'-cGMP-UMP + 2 diphosphate


name: HCCS inserts heme into cytochrome c (Rattus norvegicus)


name: [LarE protein]-dehydroalanine + pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide + AMP + diphosphate + H(+) => pyridinium-3,5-dicarboxylate mononucleotide + [LarE protein]-L-cysteine + ATP


name: (R)-4-phosphopantoate + beta-alanine + ATP => (R)-4'-phosphopantothenate + AMP + diphosphate + H(+)


name: Tyrosine is diiodinated (Canis familiaris)


name: asperaculane G + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => asperaculane E + reduced [NADPH--hemoprotein reductase] + O2


name: tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity


name: perillyl aldehyde + NADP(+) + H2O = perillate + NADPH + 2 H(+)


name: ent-isokauren-2beta-ol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => ent-isokaurene + reduced [NADPH--hemoprotein reductase] + O2


name: SRC family kinases phosphorylate ERBB2 (Drosophila melanogaster)


name: N-acetyl-L-glutamate + ATP <=> N-acetyl-L-glutamyl 5-phosphate + ADP


name: Resistant ERBB2 KD mutants do not bind AEE788 (Homo sapiens)


name: calarene + diphosphate => (2E,6E)-farnesyl diphosphate


name: glial cell-derived neurotrophic factor receptor activity


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Canis familiaris)


name: dAMP + H2O <=> 2-deoxy-D-ribose 5-phosphate + adenine


name: L-kynurenine + NADPH + O2 + H(+) = 3-hydroxy-L-kynurenine + NADP(+) + H2O


name: Arachidonate is hydroxylated to 18-HETE by CYP(1) (Bos taurus)


name: PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Caenorhabditis elegans)


name: Receptor CCR9  binds CCL25 ligand (Gallus gallus)


name: uridine(2552) in 23S rRNA + S-adenosyl-L-methionine => 2'-O-methyluridine(2552) in 23S rRNA + S-adenosyl-L-homocysteine + H(+)


name: oleanolate + UDP-alpha-D-glucose <=> oleanolate 3-O-beta-D-glucoside + UDP + H(+)


name: PEX-19 docks ABCD1/D2/D3 to peroximal membrane (Xenopus tropicalis)


name: PRKAA2 phosphorylates nuclear NFE2L2 (Rattus norvegicus)


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Homo sapiens)


name: mRNA5 is translated to protein M (Homo sapiens)


name: glyoxylate + L-aspartate => oxaloacetate + glycine


name: beta-D-glucosyl-(1->3)-D-glucose + phosphate <=> alpha-D-glucose 1-phosphate + D-glucose


name: Export of Spliced Viral mRNA (Homo sapiens)


name: (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + ubiquinol-10 + H(+) => ubiquinone-10 + trans-4-hydroxy-L-proline


name: PFK tetramer phosphorylates Fru(6)P (Drosophila melanogaster)


name: Activated JNKs phosphorylate c-JUN (Homo sapiens)


name: Elongation Of The Telomeric Chromosome End (Sus scrofa)


name: [protein]-L-glutamate 5-O-methyl ester + H2O <=> L-glutamyl-[protein] + methanol + H(+)


name: [(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-alpha-D-glucosyl](n+1) + UDP + H(+)


name: GRB2-1:SOS1 binds p-Y-SHC (Rattus norvegicus)


name: Elongating transcript encounters a lesion in the template (Canis familiaris)


name: (2-aminoethyl)phosphonate(out) + ATP + H2O => (2-aminoethyl)phosphonate(in) + ADP + phosphate + H(+)


name: factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst) (Danio rerio)


name: Beta-defensins bind microbial membranes causing disruption (Bos taurus)


name: p-T182 MAPKAPK5 phosphorylates FOXO1 (Gallus gallus)


name: Phosphorylation of PD-1 (Canis familiaris)


name: omega-dicarboxyl-CoA + H2O => a dicarboxylate + CoA + H(+)


name: 3-oxopropanoate + NADP(+) + CoA <=> acetyl-CoA + CO2 + NADPH


name: extracellular negative regulation of signal transduction


name: SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Sus scrofa)


name: a 5-formyl-2'-deoxycytidine in DNA + 2-oxoglutarate + O2 => a 5-carboxyl-2'-deoxycytidine in DNA + succinate + CO2 + H(+)


name: Loading of GABA into clathrin sculpted GABA transport vesicle lumen (Homo sapiens)


name: chloramphenicol + A + 2 H2O => alpha-N-dichloroacetyl-p-aminophenylserinol + AH2 + 2 O2


name: Dissociation of Cdc20 from APC/C complex (Homo sapiens)


name: TBC1D14 binds RAB11 and ULK1 (Rattus norvegicus)


name: SPOP:CUL3:RBX1 ubiquitinates GLI2,3 (Caenorhabditis elegans)


name: USP12, USP26 deubiquitinate AR (Gallus gallus)


name: (2Z,6Z)-farnesyl diphosphate synthase activity


name: pyridoxine 5'-phosphate + O2 <=> pyridoxal 5'-phosphate + H2O2


name: N-acetyl-D-galactosamine + ATP = N-acetyl-D-galactosamine 6-phosphate + ADP + H(+)


name: (+)-dehydrodiconiferyl acid + a quinone = (+)-dehydrodiconiferyl acid ketone + a quinol


name: (2E,6E)-farnesyl diphosphate + H2O => 10-epi-cubebol + diphosphate


name: Activated FGFR1:p-FRS binds GRB2:SOS1 (Canis familiaris)


name: glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] (Canis familiaris)


name: oxidoreductase activity, acting on metal ions, oxygen as acceptor


name: PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Gallus gallus)


name: 5-methylphenazine-1-carboxylate 1-monooxygenase (NADH) activity


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST (Danio rerio)


name: (5R,12R,14S)-dolasta-1(15),8-diene + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: dGTP(in) + UTP(out) => dGTP(out) + UTP(in)


name: diglucosyl-enterobactin + UDP + H(+) => monoglucosyl-enterobactin + UDP-alpha-D-glucose


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Bos taurus)


name: PKC alpha interacts with and phosphorylates KIT (Mus musculus)


name: sphing-4-enine 1-phosphate = (2E)-hexadecenal + phosphoethanolamine


name: I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol (Mus musculus)


name: NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Homo sapiens)


name: Start codon recognition (Caenorhabditis elegans)


name: glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] (Canis familiaris)


name: 11-cis-retinol + NAD(+) => 11-cis-retinal + NADH + H(+)


name: PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA (Plasmodium falciparum)


name: 7,8-dihydroneopterin 3'-phosphate => glycolaldehyde phosphate + 6-hydroxymethyl-7,8-dihydropterin


name: sn-glycerol 3-phosphocholine(out) = sn-glycerol 3-phosphocholine(in)


name: ornithine => putrescine + CO2 (Canis familiaris)


name: G alpha (q) in G (q):RGS complex is inactivated (Danio rerio)


name: POMK 6-phosphorylates mannose in GalNAc-GlcNAc-Man-DAG1 (Rattus norvegicus)


name: an N-(fatty acyl)-L-tyrosine + H2O = L-tyrosine + a fatty acid


name: docosanoyl-CoA + 2 NADPH + 2 H(+) => docosan-1-ol + 2 NADP(+) + CoA


name: SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Rattus norvegicus)


name: isopentenyl pyrophosphate transmembrane transporter activity


name: Exocytosis of Proactivator polypeptide (Homo sapiens)


name: L-2-aminoadipate + glyoxylate <=> 2-oxoadipate + glycine


name: IgG:Lma antigens binds FCGR3A:CD3 dimers (Homo sapiens)


name: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H2O <=> 1-guanidino-1-deoxy-scyllo-inositol + phosphate


name: PLA2s hydrolyze phospholipids at the Golgi membrane (Saccharomyces cerevisiae)


name: N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose => N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O


name: aldehydo-D-galactose 6-phosphate = keto-D-tagatose 6-phosphate


name: (E)-caffeoylpyruvate + H2O <=> (E)-caffeate + pyruvate + H(+)


name: CHST15 transfers sulfate to (6-)GalNAc-4-sulfate (Rattus norvegicus)


name: p-S256-Aquaporin-2 passively transports water into cell (Bos taurus)


name: Autophosphorylation of LTK dimer:ALKAL1,2 (Homo sapiens)


name: indole + NADH + O2 + H(+) <=> indoxyl + NAD(+) + H2O


name: L-histidine + 3 S-adenosyl-L-methionine <=> hercynine + 3 S-adenosyl-L-homocysteine + 3 H(+)


name: DEK binds TFAP2A homodimers (Drosophila melanogaster)


name: P4HB binds Collagen chains (Danio rerio)


name: TRAF3 binds TICAM1:activated TLR4 complex (Canis familiaris)


name: DENND4s exchange GTP for GDP on RAB10 (Canis familiaris)


name: GALM converts beta-D-GAL to alpha-D-GAL (Caenorhabditis elegans)


name: [(1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate


name: PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal (Gallus gallus)


name: (2R,3S)-homoisocitrate + NAD(+) = 2-oxoadipate + CO2 + NADH


name: Endosomal TLRs pass through the Golgi (Homo sapiens)


name: HDAC8 deacetylates histones (Canis familiaris)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 (Bos taurus)


name: piperine + CoA + H(+) => piperidine + (E,E)-piperoyl-CoA


name: Cysteine is degraded to pyruvate and H2S (Xenopus tropicalis)


name: 2 Co(I)-[dimethylamine-specific corrinoid protein] + A + ADP + phosphate + 3 H(+) => 2 Co(II)-[dimethylamine-specific corrinoid protein] + AH2 + ATP + H2O


name: a 1-O-alkyl-2-acetyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphocholine


name: OPTN, TBK1 bind ubiquitinated MOM proteins (Canis familiaris)


name: n isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate <=> a di-trans,poly-cis-polyprenyl diphosphate + n diphosphate


name: Translocation of PLC-gamma1 to PIP2 (Schizosaccharomyces pombe)


name: SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Rattus norvegicus)


name: DELE1(143-515) is released into the cytosol (Canis familiaris)


name: LIPT2 transfers octanoyl group to GCSH (Caenorhabditis elegans)


name: Activated MET binds RANBP9 and SOS1 (Bos taurus)


name: pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Drosophila melanogaster)


name: 1-acyl LPG is acylated to PG by LPGAT (Caenorhabditis elegans)


name: 5-carboxymethoxyuridine(34) in tRNA + S-adenosyl-L-methionine => 5-methoxycarbonylmethoxyuridine(34) in tRNA + S-adenosyl-L-homocysteine


name: cytidine(72) in tRNA(Thr) + S-adenosyl-L-methionine => 5-methylcytidine(72) in tRNA(Thr) + S-adenosyl-L-homocysteine + H(+)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[16] (Xenopus tropicalis)


name: 2,4-dinitroanisole + H2O = 2,4-dinitrophenol + methanol + H(+)


name: (E)-cinnamaldehyde + NADP(+) + CoA <=> (E)-cinnamoyl-CoA + NADPH + H(+)


name: ARL2:GTP bind PDE6D on KRAS4B (Rattus norvegicus)


name: (+)-piperitol + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+) => (+)-pinoresinol + reduced [NADPH--hemoprotein reductase] + O2


name: IP receptor can bind prostacyclin (Bos taurus)


name: CYP27A1 27-hydroxylates CHOL (Homo sapiens)


name: thiamine phosphate + ADP + H(+) => thiamine + ATP


name: pigment biosynthetic process involved in pigment granule maturation


name: OTUD7B,TNFAIP3 deubiquitinate TRAF6 (Bos taurus)


name: 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + ATP => 3-diphospho-1D-myo-inositol 1,2,4,5-tetrakisphosphate + ADP


name: decanoate + ATP + CoA = decanoyl-CoA + AMP + diphosphate


name: Methylthio-ribose-P => Methylthio-ribulose-P (Danio rerio)


name: p-MAPK2/3 phosphorylates HSP27 (Drosophila melanogaster)


name: ATRX:DAXX binds to subtelomeric chromosomal regions (Canis familiaris)


name: (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Bos taurus)


name: hypotaurine(out) + chloride(out) + 2 Na(+)(out) = hypotaurine(in) + chloride(in) + 2 Na(+)(in)


name: PRKCI phosphorylates ELF3 (Caenorhabditis elegans)


name: Assembly of IFT B complex (Homo sapiens)


name: 1D-myo-inositol hexakisphosphate + ATP <=> 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ADP


name: 4-(trimethylamino)butanal + NAD(+) + H2O = 4-(trimethylamino)butanoate + NADH + 2 H(+)


name: a ganglioside GQ1b (d18:1(4E)) + H2O = a ganglioside GT1b (d18:1(4E)) + N-acetylneuraminate


name: (11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoA + NADPH + H(+) <=> (3R)-hydroxy-(11Z,14Z,17Z)-eicosatrienoyl-CoA + NADP(+)


name: (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA + CO2 + CoA


name: (Z)-3-ureidoacrylate + H2O <=> (Z)-3-aminoacrylate + carbamate + H(+)


name: nitrous oxide + NAD(+) + H2O = 2 nitric oxide + NADH + H(+)


name: Fibronectin degradation by MMP14 (Rattus norvegicus)


name: type 1 vasoactive intestinal polypeptide receptor binding


name: RHOD binds effectors at the endosome membrane (Homo sapiens)


name: diacylglycerol + H2O -> 2-acylglycerol + fatty acid (Homo sapiens)


name: Granzyme-B activates BID by cleavage (Mus musculus)


name: Release of STAT1 dimer from active receptor unit (Homo sapiens)


name: TRAF3:NIK binds TRAF2:cIAP1/2 (Bos taurus)


name: hexadecanoyl-CoA + glycine + H(+) => 1-deoxymethyl-3-dehydrosphinganine + CO2 + CoA


name: FUT2 transfers Fuc to Type 1 chains to form H antigen-sec (Rattus norvegicus)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycerol => a 1-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: PKA phosphorylates GLI3 (Rattus norvegicus)


name: 3 2,3-dihydroxybenzoyl-5'-AMP + 3 L-seryl-5'-AMP <=> enterobactin + 6 AMP + 7 H(+)


name: D-xylulose 5-phosphate + formaldehyde = dihydroxyacetone + D-glyceraldehyde 3-phosphate


name: OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane (Drosophila melanogaster)


name: GSTs transfer GSH to NAPQI to form APAP-SG (Mus musculus)


name: Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2 (Homo sapiens)


name: ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Rattus norvegicus)


name: CYP3A4 monooxygenates ATVL to 2-OH-ATVL (Canis familiaris)


name: N(1)-acetylspermidine + CoA + H(+) => spermidine + acetyl-CoA


name: EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) (Dictyostelium discoideum)


name: 10 malonyl-CoA + 8 H(+) = tetracenomycin F2 + 10 CO2 + 10 CoA + 2 H2O


name: ORC1 binds to H4K20me2 (Caenorhabditis elegans)


name: GRB2:SOS1 complex binds to the active receptor (Caenorhabditis elegans)


name: (6S)-5-formyl-5,6,7,8-tetrahydrofolate + L-glutamate => N-formyl-L-glutamate + (6S)-5,6,7,8-tetrahydrofolate + H(+)


name: a hydroperoxide + L-cysteinyl-[protein] = S-hydroxy-L-cysteinyl-[protein] + an alcohol


name: negative regulation of acetylcholine biosynthetic process


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus (Plasmodium falciparum)


name: octanoyl-[ACP] + H2O <=> octanoate + holo-[ACP] + H(+)


name: PINK1 phosphorylates Ub on MOM proteins (Canis familiaris)


name: N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer (Plasmodium falciparum)


name: 7-oxoheptanoyl-[ACP] + oxidized [flavodoxin] + H2O <=> 6-carboxyhexanoyl-[ACP] + reduced [flavodoxin]


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus (Dictyostelium discoideum)


name: Plasma membrane glycoconjugates translocate to the cytosol (Homo sapiens)


name: FDPS dimer transfers IPPP to DMAPP (Danio rerio)


name: stimulation of nitric-oxide synthase activity


name: PTK2beta binds alphaVbeta3 (Caenorhabditis elegans)


name: AMBRA1 binds DYNLL1,DYNLL2 (Xenopus tropicalis)


name: thyroid-stimulating hormone receptor activity


name: Properdin stabilizes C3b:Bb bound to cell surfaces (Homo sapiens)


name: Galanin receptors can bind galanin (Sus scrofa)


name: PKR inhibitors bind PKR (Canis familiaris)


name: CNDP2:2Mn2+ dimer hydrolyses CysGly (Mus musculus)


name: GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region (Canis familiaris)


name: phenylacetyl-CoA + 2 a ubiquinone + H2O = phenylglyoxylyl-CoA + 2 a ubiquinol


name: 4-methylamino-4-dedimethylamino-anhydrotetracycline + S-adenosyl-L-methionine => anhydrotetracycline + S-adenosyl-L-homocysteine + H(+)


name: Methylation of GMP-cap by RNA Methyltransferase (Sus scrofa)


name: Adenylate Kinase 3 is a GTP-AMP phosphotransferase (Drosophila melanogaster)


name: negative regulation of myo-inositol trisphosphate biosynthesis


name: PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Sus scrofa)


name: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine <=> 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine + H(+)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Xenopus tropicalis)


name: glycochenodeoxycholate + NADP(+) => 7-oxoglycolithocholate + NADPH + H(+)


name: PIAS1 binds p-STAT1 dimer (Rattus norvegicus)


name: activation of butyryl-CoA catabolic process to butanol


name: a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(in) <=> a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(out)


name: N-terminal L-glutaminyl-[protein] + H2O <=> N-terminal L-glutamyl-[protein] + NH4(+)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Bos taurus)


name: Phosphorylation of CRMPs by GSK3beta (Homo sapiens)


name: Transcription of NOTCH2NLA gene (Homo sapiens)


name: RHOB binds effectors on endosomes (Canis familiaris)


name: tetradecanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine + CoA


name: C30 botryococcene + diphosphate + NADP(+) <=> presqualene diphosphate + NADPH + H(+)


name: Na(+)(in) + ATP + H2O => Na(+)(out) + ADP + phosphate + H(+)


name: (E)-caffeoyl-CoA + NADPH + H(+) => (E)-caffeyl aldehyde + NADP(+) + CoA


name: pemetrexed(in) + H(+)(in) <=> pemetrexed(out) + H(+)(out)


name: Degradation of ubiquitinated p27/p21 by the 26S proteasome (Mus musculus)


name: [thioredoxin]-disulfide + L-methionine + H2O <=> L-methionine (R)-S-oxide + [thioredoxin]-dithiol


name: 1,2-di-(9Z-octadecenoyl)-glycerol + H2O <=> 1-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)


name: CDC42 GEFs activate CDC42 (Rattus norvegicus)


name: L-amino acyl-L-seryl-[protein] + ATP <=> (S,S)-2-(C-substituted-aminomethyl)-4-acyl-2-oxazoline-[protein] + ADP + phosphate + H(+)


name: SMAD2/3:SMAD4 heterotrimer binds SP1 (Sus scrofa)


name: L-tryptophan + FADH2 + chloride + O2 <=> 7-chloro-L-tryptophan + FAD + 2 H2O


name: RGGT geranylgeranylates RAB proteins (Saccharomyces cerevisiae)


name: 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA => 1-octadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA


name: fluoroacetaldehyde + NAD(+) + H2O => fluoroacetate + NADH + 2 H(+)


name: KDM6B demethylates H3K27me3 on p16INK4A promoter (Schizosaccharomyces pombe)


name: 5-aminomethyl-2-thiouridine(34) in tRNA + S-adenosyl-L-methionine = 5-methylaminomethyl-2-thiouridine(34) in tRNA + S-adenosyl-L-homocysteine + H(+)


name: Fusion of HCMV Envelope with Plasma Membrane (Homo sapiens)


name: glutamate + acetyl CoA => N-acetyl glutamate + CoA (Xenopus tropicalis)


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Gallus gallus)


name: hexadecanoyl-AMP + holo-[ACP] = hexadecanoyl-[ACP] + AMP + H(+)


name: p-STAT1 dimer binds KPNA1 (Dictyostelium discoideum)


name: Activated FGFR2 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA (Homo sapiens)


name: Activated PCLG1 dissociates from NTRK3 (Sus scrofa)


name: 1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP => 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H(+)


name: Receptor CXCR2 binds ligands CXCL1 to 7 (Rattus norvegicus)


name: L-ribulose + ATP => L-ribulose 5-phosphate + ADP + H(+)


name: [(1->4)-alpha-D-glucosyl](n) + n ATP + n H2O = [(1->4)-6-phospho-alpha-D-glucosyl](n) + n AMP + n phosphate + 2n H(+)


name: 'de novo' NAD biosynthetic process from L-tryptophan


name: (2S)-2-[5-amino-1-(beta-D-ribosyl)imidazole-4-carboxamido]succinate(out) + ADP + phosphate + H(+) => (2S)-2-[5-amino-1-(beta-D-ribosyl)imidazole-4-carboxamido]succinate(in) + ATP + H2O


name: CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA (Homo sapiens)


name: Caspase-mediated cleavage of Lamin A (Bos taurus)


name: uridine(2479) in 23S rRNA + S-adenosyl-L-methionine <=> 2'-O-methyluridine(2479) in 23S rRNA + S-adenosyl-L-homocysteine + H(+)


name: GDNF,NRTN bind RET:GFRA1,GFRA2 (Canis familiaris)


name: fumagillol + NADP(+) => 5-dehydrofumagillol + NADPH + H(+)


name: a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + H2O = a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + choline + H(+)


name: Phosphorylation of cPLA2 by ERK-2 (Danio rerio)


name: ABCB1,ABCC2 transport ATVs from cytosol to extracellular region (Plasmodium falciparum)


name: MMACHC:cob(II)alamin binds MMADHC (Sus scrofa)


name: PHGDH tetramer dehydrogenates 3PG (Homo sapiens)


name: USP16,USP21 deubiquitinate Histone H2A (Bos taurus)


name: a ganglioside Ac-O-8-GD3(d18:1(4E)) <=> a ganglioside Ac-O-9-GD3(d18:1(4E))


name: Exocytosis of specific granule membrane proteins (Danio rerio)


name: (S)-4-aminopentanoate + NAD(+) + H2O <=> 4-oxopentanoate + NH4(+) + NADH + H(+)


name: 2-deoxy-D-glucose 6-phosphate + NAD(+) => 2-deoxy-6-phospho-D-glucono-1,5-lactone + NADH + H(+)


name: JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Rattus norvegicus)


name: (12R)-hydroxy-(9Z)-octadecenoate + reduced [NADPH--hemoprotein reductase] + O2 => (12R),18-dihydroxy-(9Z)-octadecenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: RAC2 binds effectors at the mitochondrial outer membrane (Mus musculus)


name: Nectin-1:PVRL3 trans heterodimer formation (Mus musculus)


name: ITP(out) + UTP(in) => ITP(in) + UTP(out)


name: 8-oxo-GDP + H2O <=> 8-oxo-GMP + phosphate + H(+)


name: (2S)-2-amino-4-deoxychorismate + H2O <=> (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxyate + pyruvate


name: PGH2 is isomerised to PGD2 by PTGDS (Xenopus tropicalis)


name: UDP-4-amino-4-deoxy-beta-L-arabinose + 2-oxoglutarate = UDP-beta-L-threo-pentopyranos-4-ulose + L-glutamate


name: D-mannitol(out) + N(pros)-phospho-L-histidyl-[protein] => D-mannitol 1-phosphate(in) + L-histidyl-[protein]


name: SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP (Xenopus tropicalis)


name: UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin (Sus scrofa)


name: GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Homo sapiens)


name: alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-glucuronate = beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + UDP + H(+)


name: 3-oxoheptanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyheptanoyl-[ACP] + NADP(+)


name: 4-aminobenzoate + NADH + O2 + 2 H(+) => 4-aminophenol + CO2 + NAD(+) + H2O


name: (13E)-labda-7,13-dien-15-ol + diphosphate => geranylgeranyl diphosphate + H2O


name: Degradation of multiubiquitinated Cyclin B (Xenopus tropicalis)


name: a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + L-fucose => an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GlcNAc derivative + H2O


name: a 5'-end diphospho-ribonucleoside in mRNA + phosphate + H(+) => a 5'-end triphospho-ribonucleoside in mRNA + H2O


name: ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Gallus gallus)


name: Exocytosis of azurophil granule lumen proteins (Homo sapiens)


name: phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 (Xenopus tropicalis)


name: BRCA1 binds phosphorylated RBBP8 (Mus musculus)


name: (S)-reticuline + reduced [NADPH--hemoprotein reductase] + O2 <=> 1,2-dehydroreticuline + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: 2-(9Z-octadecenoyl)-glycerol + ATP <=> 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: down regulation of NAD phosphorylation and dephosphorylation


name: Ubiquitination of stimulated EGFR (CBL:GRB2) (Rattus norvegicus)


name: activation of [2Fe-2S] cluster biosynthetic process


name: 2-sulfamoylacetyl-[peptidyl-carrier protein] + (4aR,6S,7R)-2-(adenosyl(5')diphospho(5)ribosyl)-6-hydroxy-7-amino-4-carbamoyl-4a,5,6,7-tetrahydro-2H-cyclopenta[c]pyridine-7-carboxylate = (4aR,6S,7R)-2-(adenosyl(5')diphospho(5)ribosyl)-6-hydroxy-7-acetamidosulfomoyl-4-carbamoyl-4a,5,6,7-tetrahydro-2H-cyclopenta[c]pyridine-7-carboxylate + holo-[peptidyl-carrier protein] + H(+)


name: methanol + oxaloacetate + H(+) => oxaloacetate 4-methyl ester + H2O


name: TBC1D25 accelerates GTP hydrolysis by RAB33B (Gallus gallus)


name: O-carbamoyl-L-serine + H(+) = 2-aminoprop-2-enoate + NH4(+) + CO2


name: Activated MET binds GAB1 (Gallus gallus)


name: ZnuABC transports Zn2+ to cytosol (Homo sapiens)


name: Activated FGFR4 binds PLCG1 (Drosophila melanogaster)


name: histone H3K56me2/H3K56me3 demethylase activity


name: ethylnitronate + O2 = chemical entity + acetaldehyde + nitrite + H(+)


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Dictyostelium discoideum)


name: sn-3-O-(geranylgeranyl)glycerol 1-phosphate + (2E,6E,10E)-geranylgeranyl diphosphate <=> 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + diphosphate


name: Active ALK phosphorylates JAK3 (Homo sapiens)


name: B4GALT1 binds LALBA (Drosophila melanogaster)


name: 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate => L-kynurenine + 2-oxoglutarate


name: SLC38A9 binds Ragulator:Rag dimers (Mus musculus)


name: Association of beta-catenin with the destruction complex (Sus scrofa)


name: Phosphorylation of Ribosomal protein S6 by activated S6K1 (Bos taurus)


name: Formation of lysyl-pyrrole cross-links (Rattus norvegicus)


name: AOX1 oxidises PXL to PDXate (Sus scrofa)


name: ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Rattus norvegicus)


name: E-cadherin degradation by MMP9, KLK7 (Mus musculus)


name: (2S)-hesperetin + UDP-alpha-D-glucose = (2S)-hesperetin 7-O-beta-D-glucoside + UDP + H(+)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Canis familiaris)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + L-serine + H(+)


name: Increased Muscular System Glycine Activity


name: N(2)-benzoyl-D-arginine-4-nitroanilide + H2O => N(2)-benzoyl-D-arginine + 4-nitroaniline + H(+)


name: SLC7A4 exchanges G6P for Pi across the ER membrane  (Caenorhabditis elegans)


name: Membrane depolarization upon activation of Ca impermeable AMPA receptors (Drosophila melanogaster)


name: GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Mus musculus)


name: Degradation of multiubiquitinated Nek2A (Gallus gallus)


name: hexadecanoyl-AMP + diphosphate => hexadecanoate + ATP + H(+)


name: a glycerophospholipid + H2O => a 2-acyl-sn-glycero-3-phospholipid + a fatty acid + H(+)


name: Phosphorylation of cPLA2 by MAPK p38 alpha (Bos taurus)


name: dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Dictyostelium discoideum)


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Rattus norvegicus)


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-6-O-sulfo-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + 3'-phosphoadenylyl sulfate <=> an alpha-Neu5Ac-(2->3)-6-O-sulfo-beta-D-Gal-(1->4)-6-O-sulfo-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + adenosine 3',5'-bisphosphate + H(+)


name: NEIL1 cleaves thymine glycol from damaged DNA (Sus scrofa)


name: Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 (Gallus gallus)


name: Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 (Rattus norvegicus)


name: Formation of collagen fibrils (Canis familiaris)


name: [protein]-C-terminal L-amino acid-glycyl-phosphatidylserine + H2O => 1,2-diacyl-sn-glycero-3-phospho-L-serine-N-glycine + [protein]-C-terminal <stereo>L-</stereo>amino acid


name: ACE:Zn2+ hydrolyzes AGT(25-33) (Angiotensin-(1-9)) to AGT(25-31) (Angiotensin-(1-7)) (Xenopus tropicalis)


name: S-(ADP-D-ribosyl)-L-cysteinyl-[protein] + H2O => ADP-D-ribose + L-cysteinyl-[protein]


name: Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)


name: NSF ATPase activity dissociates cis-SNARE (Gallus gallus)


name: a 1,2-diacylglycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)


name: D-fructopyranose(out) + Na(+)(out) <=> D-fructopyranose(in) + Na(+)(in)


name: Formation of DSIF complex  (Caenorhabditis elegans)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + 2 S-adenosyl-L-homocysteine + H(+) => a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + 2 S-adenosyl-L-methionine


name: GAMT gene expression is stimulated by MECP2 (Homo sapiens)


name: SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol (Homo sapiens)


name: DNA biosynthesis involved in DNA replication during S phase involved in mitotic cell cycle


name: L-leucine + (5Z,8Z,11Z,14Z)-eicosatetraenoate => N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-leucine + H2O


name: SPRY2 is serine phosphorylated in response to MAPK activation (Rattus norvegicus)


name: 2-oxohexanoate + L-kynurenine <=> L-2-aminohexanoate + kynurenate + H2O


name: SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen (Caenorhabditis elegans)


name: Active PLC-gamma1 dissociates from EGFR (Xenopus tropicalis)


name: SLC36A4 transports extracellular L-Pro to the cytosol (Bos taurus)


name: an N(1)-methyladenosine in mRNA + S-adenosyl-L-homocysteine + H(+) => an adenosine in mRNA + S-adenosyl-L-methionine


name: (5Z,8Z,11Z,14Z)-eicosatetraenamide + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + NH4(+)


name: Nonendonucleolytic RISC binds exactly matching target RNAs (Rattus norvegicus)


name: arsenic triglutathione + 2 [thioredoxin]-dithiol + 2 S-adenosyl-L-methionine + H2O => dimethylarsinous acid + 2 [thioredoxin]-disulfide + 3 glutathione + 2 S-adenosyl-L-homocysteine + 2 H(+)


name: Furin cleaves pro-prothrombin to prothrombin (Bos taurus)


name: a ganglioside GM1 + H2O => beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-D-Glc + an N-acyl-sphingoid base


name: LDH tetramer reduces PYR to LACT (Mus musculus)


name: STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Bos taurus)


name: Activated FGFR1:p-FRS phosphorylates PPTN11 (Canis familiaris)


name: activation of non-canonical NF-KB signaling


name: a bacteriochlorophyllide d + S-adenosyl-L-methionine + H2O <=> a 7(1)-hydroxybacteriochlorophyllide d + 5'-deoxyadenosine + L-methionine + H(+)


name: Displacement of UNG glycosylase by APEX1 at the AP site (Sus scrofa)


name: 3,6,8,9-tetrahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + NADPH + O2 + H(+) = 2,3,6,8,9-pentahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + NADP(+) + H2O


name: (1S,2S)-1,2-dihydrobenzene-1,2-diol + NADP(+) => catechol + NADPH + H(+)


name: TBC1D25 (OATL1) binds ATG8 homologues (Bos taurus)


name: RNF20:RNF40 monoubiquitinates Histone H2B (Rattus norvegicus)


name: 3-methoxytyramine + S-adenosyl-L-methionine <=> N-methyl-3-methoxytyramine + S-adenosyl-L-homocysteine + H(+)


name: Self-ubiquitination of RNF41 (Gallus gallus)


name: Brevican degradation by MMP1, 2, 3, 7,8,10,13,19 (Mus musculus)


name: (S)-2-chloropropanoate + NADP(+) <=> 2-chloroacrylate + NADPH + H(+)


name: PolyUb-Misfolded proteins bind vimentin to form aggresome (Bos taurus)


name: SLC41A1,2 transport Mg2+ from extracellular region to cytosol (Rattus norvegicus)


name: L-valine(in) + ADP + phosphate + H(+) => L-valine(out) + ATP + H2O


name: Creatine transport across the plasma membrane (Rattus norvegicus)


name: FLVCR1-1 transports heme from cytosol to extracellular region (Canis familiaris)


name: RHOD:GTP recruits DAIPH2-3 to endosomes (Drosophila melanogaster)


name: ADP-D-ribose + acetate + H(+) => 2''-O-acetyl-ADP-D-ribose + H2O


name: NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Danio rerio)


name: ATP binds G-protein beta associated TRiC/CCT (Drosophila melanogaster)


name: isopentenyl diphosphate + ADP + phosphate + CO2 => (R)-5-diphosphomevalonate + ATP


name: Formation of fatty acid synthase (FAS) dimer (Rattus norvegicus)


name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Bos taurus)


name: Hemoglobin A is protonated and carbamated causing release of oxygen (Rattus norvegicus)


name: PTPS is phosphorylated by cGMP-dependant protein kinase II (Bos taurus)


name: enoyl-[acyl-carrier-protein] reductase (NADH) activity


name: Demethylase KDM1A binds KLK2 and KLK3 promoters (Schizosaccharomyces pombe)


name: Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Drosophila melanogaster)


name: Alkalization of the phagosomal lumen by NOX2 (Rattus norvegicus)


name: 1-dodecanoyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA <=> 1-dodecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA


name: 3-hydroxyphenylacetate + NADPH + O2 + H(+) = homogentisate + NADP(+) + H2O


name: A + NH4(+) + 2 ADP + 2 phosphate + H(+) = hydroxylamine + AH2 + 2 ATP + H2O


name: a (3R)-3-hydroxyacyl-CoA + NAD(+) <=> a 3-oxoacyl-CoA + NADH + H(+)


name: Activated FGFR2:p-FRS bind to PPTN11 (Homo sapiens)


name: p-STAT1:p-STAT4 translocates to the nucleus (Mus musculus)


name: pre-putrebactin + ATP => putrebactin + AMP + diphosphate + H(+)


name: validoxylamine A + 2-oxoglutarate + O2 <=> validoxylamine B + succinate + CO2 + H(+)


name: an aromatic L-alpha-amino acid + 4-methylsulfanyl-2-oxobutanoate <=> an aromatic oxo-acid + L-methionine


name: (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Homo sapiens)


name: N-terminal N(alpha)-acetyl-L-seryl-[histone H2A] + CoA + H(+) => N-terminal L-seryl-[histone H2A] + acetyl-CoA


name: dinucleotide insertion or deletion binding


name: SLC45A3 transports Glc from extracellular region to cytosol (Xenopus tropicalis)


name: uroporphyrin III(in) + ATP + H2O <=> uroporphyrin III(out) + ADP + phosphate + H(+)


name: sucrose + H2O <=> beta-D-fructose + alpha-D-glucose


name: Endorepellin binds KDR (VEGFR2) (Drosophila melanogaster)


name: PIP3 binds to RhoA and activates it (Canis familiaris)


name: NKX2-5 binds the GATA6 gene (Homo sapiens)


name: 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(in) + Na(+)(in) => 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(out) + Na(+)(out)


name: a beta-D-galactoside + acetyl-CoA <=> a 6-acetyl-beta-D-galactoside + CoA


name: (13R)-S-cysteinylglycyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + L-glutamate => (13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O


name: O-(N-acetyl-alpha-D-glucosaminyl)-trans-4-hydroxy-L-prolyl-[Skp1 protein] + UDP + H(+) => trans-4-hydroxy-L-prolyl-[Skp1 protein] + UDP-N-acetyl-alpha-D-glucosamine


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Xenopus tropicalis)


name: NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Homo sapiens)


name: (R)-prunasin + UDP + H(+) => (R)-mandelonitrile + UDP-alpha-D-glucose


name: p-S215 FOXO3 translocates to the nucleus (Drosophila melanogaster)


name: ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA (Sus scrofa)


name: Hemoglobin:Haptoglobin:CD163 is endocytosed (Sus scrofa)


name: (1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FADH2 + chloride + O2 = (5-chloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O


name: tetrahydrocurcumin + NADP(+) => dihydrocurcumin + NADPH + H(+)


name: acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming]


name: SLC9A9 exchanges Na+ for H+ across the late endosome membrane (Gallus gallus)


name: (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate + H2O => (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate


name: NPC1L1 binds ezetimibe (Saccharomyces cerevisiae)


name: PCK1 phosphorylates OA to yield PEP (Drosophila melanogaster)


name: activation of iron superoxide oxidoreductase


name: peroxisomal 3-oxoacyl coenzyme A thiolase


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Homo sapiens)


name: PC is hydrolysed to 2-acyl LPC by PLA2[7] (Mus musculus)


name: P2Y4 receptor can bind to UTP (Rattus norvegicus)


name: 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Homo sapiens)


name: activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)


name: carboxymethoxysuccinate => glycolate + fumarate


name: GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) (Bos taurus)


name: HGSNAT oligomer acetylates Heparan sulfate chain(3) (Drosophila melanogaster)


name: Increased Muscular System Substance P Activity


name: DAG1(30-653) and DAG1(654-895) translocate to the Golgi (Rattus norvegicus)


name: (8Z,11Z,14Z)-eicosatrienoate + O2 => (15S)-hydroperoxy-(8Z,11Z,13E)-eicosatrienoate


name: precorrin-6B + 2 S-adenosyl-L-methionine => precorrin-8X + 2 S-adenosyl-L-homocysteine + CO2 + 3 H(+)


name: TM7SF2 reduces 4,4-diMeCholesta-8,14-dien-3-ol to 4,4-diMe5-cholest-8-en-3-ol (Schizosaccharomyces pombe)


name: L-lysyl(36)-[histone H3] + 2 S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 S-adenosyl-L-homocysteine + 2 H(+)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Plasmodium falciparum)


name: RAN stimulates fusion of nuclear envelope (NE) membranes (Drosophila melanogaster)


name: pro-RAS proteins are farnesylated (Rattus norvegicus)


name: 4-hydroxy-3-(all-trans-hexaprenyl)benzoate + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) <=> 3,4-dihydroxy-5-(all-trans-hexaprenyl)benzoate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + O2 <=> (2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + H2O2


name: an N(1)-methyladenosine in tRNA + 2-oxoglutarate + O2 <=> an adenosine in tRNA + formaldehyde + succinate + CO2


name: 1-chloro-3-nitrobenzene + NADH + O2 = 4-chlorocatechol + nitrite + NAD(+)


name: WNTs are secreted in exosomes (Sus scrofa)


name: CMP-N-acetyl-7-O-acetyl-beta-neuraminate + CoA => CMP-N-acetyl-beta-neuraminate + acetyl-CoA


name: PTPN1 and PTPN2 dephosphorylate MET (Canis familiaris)


name: NOTCH1 associates with negative regulators NUMB and ITCH (Homo sapiens)


name: positive regulation of septation initiation signaling


name: inosine(in) + H(+)(out) = inosine(out) + H(+)(in)


name: PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Dictyostelium discoideum)


name: 2-(9Z-octadecenoyl)-glycerol + tetradecanoyl-CoA => 1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: MeSeO2H is reduced to MeSeOH by TXNRD1 (Mus musculus)


name: SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Danio rerio)


name: positive regulation of tensidol A biosynthetic process


name: TBC1D15 accelerates GTP hydrolysis by RAB7 (Rattus norvegicus)


name: L-aspartate + NAD(+) + H2O => oxaloacetate + NH4(+) + NADH + H(+)


name: [5-(aminomethyl)-3-furyl]methyl phosphate + ATP = [5-(aminomethyl)furan-3-yl]methyl diphosphate + ADP


name: PTPN11 dephosphorylates RUNX1 (Sus scrofa)


name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) (Rattus norvegicus)


name: PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Dictyostelium discoideum)


name: BACH1 translocates from the cytosol to the nucleoplasm (Rattus norvegicus)


name: RNA Polymerase II Promoter Opening: First Transition (Saccharomyces cerevisiae)


name: taurocholate(out) + glutarate(in) = taurocholate(in) + glutarate(out)


name: SLC25A12,13 exchange L-Glu and L-Asp (Sus scrofa)


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Gallus gallus)


name: (S)-dihydroorotate + fumarate = orotate + succinate


name: Tenascins C, R, (X, N) bind lecticans (Canis familiaris)


name: Formation of the closed pre-initiation complex (Caenorhabditis elegans)


name: PRDX5 reduces peroxynitrite to nitrite using TXN (Sus scrofa)


name: GNLY binds the bacterial cell surface in the phagosome (Homo sapiens)


name: RHO1:GDP complex dissociates from RHOGDI and binds to the plasma membrane (Drosophila melanogaster)


name: Interaction of SHP1 and KIT (Homo sapiens)


name: 2-nitroimidazole + H2O = 1,3-dihydro-2H-imidazol-2-one + nitrite + H(+)


name: p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Mus musculus)


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Danio rerio)


name: GMP + 2 phosphate + 2 H(+) => GTP + 2 H2O


name: Binding of ADAR2 homodimer to dsRNA duplex (Bos taurus)


name: The 60S subunit joins the translation initiation complex  (Canis familiaris)


name: cis-Golgi cis-SNARE binds NSF and SNAPs (Gallus gallus)


name: a 3-oxo-Delta(1)-steroid + H2O => a 1-hydroxy-3-oxo steroid


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Mus musculus)


name: N-[(3R)-3-hydroxyhexadecanoyl]-glycine + hexadecanoyl-[ACP] = N-[(3R)-3-(hexadecanoyloxy)hexadecanoyl]-glycine + holo-[ACP]


name: a 1,2-diacyl-sn-glycero-3-phosphoglycerol + H2O <=> glycerol 1-phosphate + a 1,2-diacyl-sn-glycerol + H(+)


name: Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Caenorhabditis elegans)


name: 3,4-dihydroxy-5-methoxyphenethylamine + S-adenosyl-L-methionine => 4-hydroxy-3,5-dimethoxyphenethylamine + S-adenosyl-L-homocysteine + H(+)


name: a 3-oxo-Delta(1)-steroid + H2O <=> a 1-hydroxy-3-oxo steroid


name: N(6)-(dimethylallyl)adenosine 5'-phosphate + H2O = N(6)-dimethylallyladenine + D-ribose 5-phosphate


name: cholate 7-alpha-dehydrogenase (NAD+) activity


name: (2R)-2-hydroxy-4-(methylsulfanyl)butanoate + S-adenosyl-L-methionine <=> (2R)-4-(dimethylsulfaniumyl)-2-hydroxybutanoate + S-adenosyl-L-homocysteine


name: 5-(methylsulfanyl)-D-ribulose 1-phosphate => 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O


name: G-protein coupled bile acid receptor binds lithocholic acid (Drosophila melanogaster)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O <=> sn-glycerol 3-phosphocholine + hexadecanoate + H(+)


name: firefly oxyluciferin + hnu + AMP + CO2 + diphosphate => firefly D-luciferin + ATP + O2


name: 18-hydroxy-(9Z,12Z)-octadecadienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => (9Z,12Z)-octadecadienoate + reduced [NADPH--hemoprotein reductase] + O2


name: Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz (Bos taurus)


name: FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Canis familiaris)


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Rattus norvegicus)


name: transmembrane conductance regulator activity


name: methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Danio rerio)


name: tryprostatin A + reduced [NADPH--hemoprotein reductase] + O2 <=> fumitremorgin C + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: N-methyltyramine + S-adenosyl-L-homocysteine + H(+) => tyramine + S-adenosyl-L-methionine


name: DCN binds collagen I, II, III, VI fibrils (Danio rerio)


name: FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Caenorhabditis elegans)


name: CYP3A4 can N-demethylate loperamide (Mus musculus)


name: RUNX1 binds SIN3A,(SIN3B) co-repressor (Homo sapiens)


name: N-tetracosanoylsphinganine + H2O => tetracosanoate + sphinganine


name: PLB1 hydrolyses RPALM to atROL (Sus scrofa)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate


name: Sequestration of BAD protein by 14-3-3 (Mus musculus)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + S-adenosyl-L-methionine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleoside) in mRNA + S-adenosyl-L-homocysteine + H(+)


name: PTHP is reduced to BH4 by sepiapterin reductase (SPR) (Dictyostelium discoideum)


name: Formation of Ragulator complex (Sus scrofa)


name: CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression (Drosophila melanogaster)


name: Translocation of SCP, Triplex (TRI) complex, CVC complex, and Accessory Proteins from the cytoplasm into the nucleous (Homo sapiens)


name: TBC1D7 binds the TSC1-TSC2 complex (Canis familiaris)


name: a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine(in) + H(+)(in) => a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine(out) + H(+)(out)


name: EP300 is recruited to MYC and BCL2 genes (Mus musculus)


name: mycophenolate + UDP-alpha-D-glucuronate = mycophenolate 7-O-beta-D-glucuronide + UDP + H(+)


name: STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Drosophila melanogaster)


name: inhibition of asperfuranone biosynthetic process


name: benzoyl-CoA + L-lysyl-[protein] = N(6)-benzoyl-L-lysyl-[protein] + CoA + H(+)


name: eicosanyl hexadecanoate + CoA => eicosan-1-ol + hexadecanoyl-CoA


name: oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor


name: "With an iron-sulfur protein as acceptor"


name: urate(out) + 2 Na(+)(out) => urate(in) + 2 Na(+)(in)


name: heme b + 3 AH2 + 3 O2 + 2 H(+) = mycobilin a + Fe(2+) + 3 A + 3 H2O


name: (6R)-L-erythro-6,7-dihydrobiopterin + NADH + H(+) => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + NAD(+)


name: 1,2-diheptanoyl-sn-glycero-3-phosphocholine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-heptanoyl-sn-glycero-3-phosphocholine + 1-heptanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine


name: BAR domain proteins recruit dynamin (Caenorhabditis elegans)


name: I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Dictyostelium discoideum)


name: D-cellotetraono-1,5-lactone + H2O = D-cellotetraonate + H(+)


name: Raf dimer inhibitors bind RAF heterodimers (Caenorhabditis elegans)


name: sulfoacetaldehyde + NADP(+) + CoA <=> sulfoacetyl-CoA + NADPH + H(+)


name: LRRC16A binds F-actin capping protein (Sus scrofa)


name: S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-cysteinyl-[protein] + CoA => L-cysteinyl-[protein] + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA


name: positive regulation of cholesterol import


name: HINT1, SIN3A and HDAC1 bind MITF-M at the BCL2 promoter (Caenorhabditis elegans)


name: MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Mus musculus)


name: USP44 deubiquitinates CDC20 (Homo sapiens)


name: Noradrenaline clearance from the synaptic cleft (Rattus norvegicus)


name: 1-hexadecanoyl-sn-glycero-3-phosphate + phosphate => hexadecanoyl phosphate + sn-glycerol 3-phosphate


name: Glutamine transport from astrocytes (Rattus norvegicus)


name: isopentenyl phosphate + ATP <=> isopentenyl diphosphate + ADP


name: Opioid receptors bind opioid peptides (Bos taurus)


name: OGDH dimer decarboxylates 2-OG (Homo sapiens)


name: Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.  (Caenorhabditis elegans)


name: protein-phosphocysteine-galactitol-phosphotransferase system transporter activity


name: AURKA phosphorylates TP53 (Homo sapiens)


name: MTMR12 binds MTM1 (Drosophila melanogaster)


name: HTR3 pentamers:5HT transport Na+,K+,Ca2+ (Mus musculus)


name: STAT4 binds IL12RB2:IL12RB2 (Bos taurus)


name: SUMOylation of TOP2A with SUMO1 (Xenopus tropicalis)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Sus scrofa)


name: a  beta-D-glucosyll-(1<->1')-sphingoid base + a fatty acid => a beta-D-glucosylceramide + H2O


name: dihydroserpentine + A = serpentine + AH2


name: Intermediate 1 binds HP subcomplex to form Intermediate 2 (Mus musculus)


name: MDM2 translocates to the nucleus (Gallus gallus)


name: myricetin 3-O-beta-D-glucoside + UDP-alpha-D-glucose <=> myricetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP + H(+)


name: L-aspartate + 3 NADPH + 3 O2 + 2 H(+) => 2-nitrobutanedioate + 3 NADP(+) + 4 H2O


name: RAB21 GEFs exchange GTP for GDP on RAB21 (Homo sapiens)


name: pristanoyl-CoA + H2O <=> 2,6,10,14-tetramethylpentadecanoate + CoA + H(+)


name: Formation of ADAR1 homodimer (Bos taurus)


name: USP20, USP33 deubiquitinate ADRB2 (Rattus norvegicus)


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Dictyostelium discoideum)


name: GTP-bound RAC contributes to JNK activation (Danio rerio)


name: [(1->4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine => [(1->4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)


name: Recruitment of SHC1 is mediated by Y593 of the common beta chain (Bos taurus)


name: PPP1CC dephosphorylates PLK1 (Saccharomyces cerevisiae)


name: UDP-N-acetyl-alpha-D-mannosaminouronate + N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate = beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + UDP + H(+)


name: RGGT geranylgeranylates RAB proteins (Canis familiaris)


name: NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Plasmodium falciparum)


name: an anthocyanidin + UDP-alpha-D-glucose + H(+) => an anthocyanidin 3-O-beta-D-glucoside + UDP


name: S-adenosyl-L-homocysteine + H2O = S-(5-deoxy-D-ribos-5-yl)-L-homocysteine + adenine


name: serotonin-gated chloride channel activity


name: cephaeline + S-adenosyl-L-methionine => emetine + S-adenosyl-L-homocysteine + H(+)


name: ATP binding to HSP90 triggers conformation change (Sus scrofa)


name: nitrous oxide + H2O = 2 e(-) + 2 nitric oxide + 2 H(+)


name: Oxidation of cholesterol to 22beta-hydroxycholesterol (Bos taurus)


name: N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-asparaginyl-[protein] + UDP + H(+)


name: (2E,6E)-farnesyl diphosphate = germacrene A + diphosphate


name: SHP1 and SHP2 bind the common beta chain (Homo sapiens)


name: TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Xenopus tropicalis)


name: inhibition of extrinsic apoptotic signaling pathway via death domain receptors


name: D-ribitol 5-phosphate + NADP(+) = D-ribulose 5-phosphate + NADPH + H(+)


name: RDH13 reduces atRAL to atROL (Caenorhabditis elegans)


name: STUB1 polyubiquitinates RUNX2 (Mus musculus)


name: Gq-BTK complex dissociates to Active BTK and Gq (Bos taurus)


name: cytidine(3782) in 28S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(3782) in 28S rRNA + S-adenosyl-L-homocysteine + H(+)


name: a 3beta-hydroxy-4alpha-methylsteroid-4beta-carboxylate + 3 NAD(+) + 4 H2O => a 3beta-hydroxy-4,4-dimethylsteroid + 3 NADH + 3 O2 + 2 H(+)


name: HMOX1 dimer translocates from ER membrane to mitochondrial outer membrane (Xenopus tropicalis)


name: a phtalamide + H2O <=> phthalate + a primary amine


name: PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Mus musculus)


name: 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA <=> 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA


name: pyruvate transmembrane transporter activity


name: MPC1:MPC2 imports PYR, H+ to mitochondrial matrix (Homo sapiens)


name: WWTR1 (TAZ), TBX5, and PCAF form a complex (Homo sapiens)


name: activation of calcium-mediated signaling involved in cellular response to Ca2+ ion


name: dsDNA:AIM2 clusters bind ASC (Homo sapiens)


name: 8-demethyltetracenomycin C + dTDP-beta-L-rhamnose = 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C + dTDP + H(+)


name: lead ion transmembrane transporter activity


name: Formation of meiotic heteroduplex (Homo sapiens)


name: 5 (S)-methylmalonyl-CoA + malonyl-CoA + 5 NADPH + 11 H(+) = 10-deoxymethynolide + 6 CO2 + 5 NADP(+) + 6 CoA + 2 H2O


name: Activated FGFR1 binds FRS3 (Mus musculus)


name: AFG3L2 degrades mitochondrial inner membrane proteins (Canis familiaris)


name: lipid A + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) => lipid A 4'-(2-aminoethyl diphosphate) + a 1,2-diacyl-sn-glycerol


name: 2-oxoglutarate + NADPH + H(+) => (R)-2-hydroxyglutarate + NADP(+)


name: TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Sus scrofa)


name: L-dopa + NADH + H(+) = 3-(3,4-dihydroxyphenyl)propanoate + NH4(+) + NAD(+)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) <=> a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2


name: paromamine + UDP-alpha-D-kanosamine = kanamycin C + UDP + H(+)


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Rattus norvegicus)


name: (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal => all-trans-zeaxanthin + O2


name: sulforaphane + sulfate => (Z)-4-methylsufinylbutyl-N-(sulfonatooxy)methanimidothioate


name: FAD + NADPH + O2 + 2 H(+) => FADH2-C4alpha-hydroperoxide + NADP(+)


name: PPTN11 dephosphorylates SPRY2 (Canis familiaris)


name: desmethyldescarbamoylnovobiocin + dTDP + H(+) => dTDP-4-O-demethyl-beta-L-noviose + novobiocic acid


name: 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Dictyostelium discoideum)


name: 2 (2E,6E,10E)-geranylgeranyl diphosphate + NADPH + H(+) => all-trans-lycopaoctaene + 2 diphosphate + NADP(+)


name: NTPDase5 hydrolyzes nucleoside diphosphates (Homo sapiens)


name: (9Z)-hexadecenoyl-CoA + H2O <=> S-(9Z-hexadecenoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)


name: N,1-diacyl-sn-glycero-3-phosphoethanolamine + H2O = an N-acylethanolamine + a 1-acyl-sn-glycero-3-phosphate + H(+)


name: (2R,3S)-tartrate + NAD(+) <=> 2-hydroxy-3-oxosuccinate + NADH + H(+)


name: Activated FGFR4 phosphorylates FRS3 (Danio rerio)


name: (9Z)-tetradecenoyl-CoA + H2O => S-(9Z-tetradecenoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)


name: 1,2-didodecanoyl-3-beta-D-galactosyl-sn-glycerol + H2O = dodecanoyl-3-beta-D-galactosyl-sn-glycerol + dodecanoate + H(+)


name: ACLY tetramer transforms CIT to Ac-CoA (Schizosaccharomyces pombe)


name: Phosphorylation of BCAR1 by SRC-PTK2 complex (Rattus norvegicus)


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 (Danio rerio)


name: 4-chlorobenzoate + ATP + CoA => 4-chlorobenzoyl-CoA + AMP + diphosphate


name: KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 (Bos taurus)


name: CUL3:RBX1 ubiquitinates KEAP1 (Caenorhabditis elegans)


name: RCHY1 binds alanine-tailed nascent peptide and Ub:UBE2D2 (Rattus norvegicus)


name: decanedioyl-CoA + O2 = (2E)-decenedioyl-CoA + H2O2


name: (20S)-protopanaxadiol + UDP-alpha-D-glucose <=> (20S)-ginsenoside C-K + UDP + H(+)


name: CYP2U1 19-hydroxylates ARA (Mus musculus)


name: CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 (Rattus norvegicus)


name: WLS dissociates from retromer (Gallus gallus)


name: BCO2:Fe2+ cleaves betaC to APO10al and bION (Bos taurus)


name: positive regulation of proline oxidation


name: an N(7)-methylguanosine in mRNA + S-adenosyl-L-homocysteine => a guanosine in mRNA + S-adenosyl-L-methionine


name: Defective SLC34A2 does not cotransport HPO4(2-), 3Na+ from extracellular region to cytosol (Homo sapiens)


name: Phosphorylated Cdc6 is exported from the nucleus (Bos taurus)


name: alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Rattus norvegicus)


name: Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Mus musculus)


name: isopimara-7,15-dienal + NADP(+) + H2O = isopimarate + NADPH + 2 H(+)


name: p-STAT1 and p-STAT4 dissociate from IL12RB2:IL6ST receptor (Mus musculus)


name: heme B transmembrane transporter activity


name: Autocatalytic phosphorylation of FGFR2b (Caenorhabditis elegans)


name: SMURF2 binds AXIN (Drosophila melanogaster)


name: very long-chain fatty acyl-CoA hydrolase activity


name: a very long-chain fatty acyl-CoA + H2O = a very long-chain fatty acid + CoA + H(+)


name: 3,3',5-triiodo-L-thyronine(in) + L-glutamate(out) => 3,3',5-triiodo-L-thyronine(out) + L-glutamate(in)


name: 2-(9Z-octadecenoyl)-glycerol + dodecanoyl-CoA => 1-dodecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: 5,10-dihydrophenazine-1,6-dicarboxylate + O2 => phenazine-1,6-dicarboxylate + H2O2


name: TBC1D20 binds RAB1:GTP (Saccharomyces cerevisiae)


name: atROL binds RBP1 (parenchymal cell) (Drosophila melanogaster)


name: a globoside GalGb4Cer (d18:1(4E)) + GDP-beta-L-fucose <=> a globoside Globo-H (d18:1(4E)) + GDP + H(+)


name: OMA1 hydrolyzes YME1L1 (Saccharomyces cerevisiae)


name: Corticotropin cleavage from POMC (Canis familiaris)


name: (3S)-3-hydroxy-L-asparaginyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2 => L-asparaginyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2


name: a 2'-deoxyribonucleoside 5'-diphosphate + ADP => a 2'-deoxyribonucleoside 5'-phosphate + ATP


name: D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+)


name: TNF-mediated dimerization of procaspase-8 (Homo sapiens)


name: pathogen associated molecular pattern receptor activity


name: AMP + diphosphate <=> 5-phospho-alpha-D-ribose 1-diphosphate + adenine


name: (3Z)-6-oxohex-3-enoyl-CoA + formate + H(+) => 2,3-epoxy-2,3-dihydrobenzoyl-CoA + 2 H2O


name: TST transfers sulfur from S2O3(2-) to HCN to form HSCN (Schizosaccharomyces pombe)


name: LARGE1,2 elongates matriglycan chain with Xyl (Bos taurus)


name: KRAB-ZNF / KAP Interaction (Drosophila melanogaster)


name: (R)-2-hydroxypropyl-coenzyme M => (R)-1,2-epoxypropane + coenzyme M


name: L-valine(out) + ATP + H2O => L-valine(in) + ADP + phosphate + H(+)


name: Proteasomal cleavage of substrate (26S proteasome catalyst) (Homo sapiens)


name: CDP-choline + H2O = phosphocholine + CMP + 2 H(+)


name: 5D-5-O-methyl-chiro-inositol + NADP(+) <=> 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + NADPH + H(+)


name: MARK3 phosphorylates KSR1 (Canis familiaris)


name: gamma-humulene + diphosphate => (2E,6E)-farnesyl diphosphate


name: fenbendazole + reduced [NADPH--hemoprotein reductase] + O2 = 4'-hydroxyfenbendazole + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 20beta-dihydrocorticosterone + NADP(+) => corticosterone + NADPH + H(+)


name: pregna-4,9(11)-diene-3,20-dione + AH2 + O2 <=> 9,11alpha-epoxypregn-4-ene-3,20-dione + A + H2O


name: ITCH ubiquitinates DTX (Drosophila melanogaster)


name: 1-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine + H2O <=> 1-O-(9Z-octadecenyl)-sn-glycero-3-phosphate + choline + H(+)


name: psoralen + acetone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+) => (7S)-marmesin + reduced [NADPH--hemoprotein reductase] + O2


name: histone H2AK127 ubiquitin ligase activity


name: 55S ribosome:MTRF1 hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed (Sus scrofa)


name: bis(beta-D-gentiobiosyl) crocetin + UDP + H(+) => beta-D-gentiobiosyl beta-D-glucosyl crocetin + UDP-alpha-D-glucose


name: 1-beta-D-galactosyl-2,3-didodecanoyl-sn-glycerol + H2O => 1-beta-D-galactosyl-dodecanoyl-sn-glycerol + dodecanoate + H(+)


name: (2E,13Z,16Z,19Z,22Z)-octacosapentaenoyl-CoA + NADPH + H(+) => (13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA + NADP(+)


name: Alpha1-Microglobulin binds heme (Rattus norvegicus)


name: Tankyrase ADP-ribosylates AXIN (Mus musculus)


name: (2S)-2-amino-3-oxobutanoate + H(+) <=> aminoacetone + CO2


name: cocaine + H2O = ecgonine methyl ester + benzoate + H(+)


name: (-)-dehydrodiconiferyl alcohol + NADPH + H(+) <=> (S)-isodihydrodehydrodiconiferyl alcohol + NADP(+)


name: resorcinol + FADH2 + O2 => benzene-1,2,4-triol + FAD + H2O + H(+)


name: Activation of MAP3K7 in response to WNT (Homo sapiens)


name: USP13 and OTUD3 deubiquitinate PTEN (Rattus norvegicus)


name: L-phenylalanyl-tRNA(Phe) + acetyl-CoA => N-acetyl-L-phenylalanyl-tRNA(Phe) + CoA


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 <=> 20-hydroxy-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: positive regulation of lysosomal protein catabolic process


name: dAMP + H2O = 2'-deoxyadenosine + phosphate


name: 1D-myo-inositol hexakisphosphate + ADP + H(+) => 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP


name: (+)-copalyl diphosphate <=> isopimara-7,15-diene + diphosphate


name: L-leucine(in) + H(+)(out) => L-leucine(out) + H(+)(in)


name: 1-acyl LPE is acylated to PE by LPEAT (Rattus norvegicus)


name: Elongation of arachidonyl-CoA to docosatetraenoyl-CoA (Dictyostelium discoideum)


name: 4-hydroxybutanoate + NADP(+) => succinate semialdehyde + NADPH + H(+)


name: KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 (Drosophila melanogaster)


name: PTPN1 (PTP1B) dephosphorylates tyrosine-24 of ANXA2 (Annexin-2) (Sus scrofa)


name: MMP14 (MT1-MMP) binds TIMP2 (Homo sapiens)


name: ZRANB1 binds APC (Drosophila melanogaster)


name: Activation of Rac1 by VAV2 (Canis familiaris)


name: AKT1 E17K mutant phosphorylates p21Cip1 and p27Kip1 (Homo sapiens)


name: tryprostatin A + reduced [NADPH--hemoprotein reductase] + O2 = fumitremorgin C + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: IL18:IL18R1 binds IL18RAP (Mus musculus)


name: PIAS2-1 SUMOylates PARK7 with SUMO1 (Mus musculus)


name: Factor VIIIa dissociates  (Gallus gallus)


name: WNTs are secreted in exosomes (Gallus gallus)


name: CHIP (STUB1) mediates ubiquitination of ERBB2 (Rattus norvegicus)


name: interleukin-1, type I, activating receptor activity


name: nitrite + 6 reduced [2Fe-2S]-[ferredoxin] + 8 H(+) => 6 oxidized [2Fe-2S]-[ferredoxin] + NH4(+) + 2 H2O


name: Activation of IKK complex (Mus musculus)


name: methylphosphonate + ATP => alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine


name: 2-dehydro-3-deoxy-D-gluconate + NADP(+) => (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NADPH + H(+)


name: MOGS removes terminal glucose from Glu3Man9GlcNAc2-CDH1 (Drosophila melanogaster)


name: 3-methylxanthine + NADPH + O2 + H(+) = xanthine + formaldehyde + NADP(+) + H2O


name: RAC2 translocates to the phagocytic vesicle membrane (Dictyostelium discoideum)


name: hydroxylamine + 4 Fe(III)-[cytochrome c] + H2O <=> 4 Fe(II)-[cytochrome c] + nitrite + 5 H(+)


name: 2 reduced [4Fe-4S]-[ferredoxin] + NADP(+) + H(+) <=> 2 oxidized [4Fe-4S]-[ferredoxin] + NADPH


name: 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP(+) + H2O => 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADPH + O2 + H(+)


name: Activated FGFR3 binds PLCG1 (Gallus gallus)


name: 3beta-hydroxyandrost-5-en-17-one + 3'-phosphoadenylyl sulfate <=> dehydroepiandrosterone 3-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: Aquaporin-3 passively transports water out of cell (Schizosaccharomyces pombe)


name: APBB1 and MAPK8 bind diphosphorylated H2AFX (Homo sapiens)


name: RAC2 GAPs stimulate RAC2 GTPase activity (Dictyostelium discoideum)


name: Formation of ORC(1-6) complex (Homo sapiens)


name: Met-tRNAi binds to eIF2:GTP to form the ternary complex (Plasmodium falciparum)


name: SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine (Bos taurus)


name: 9alpha-copalyl diphosphate = isopimara-8(14),15-diene + diphosphate


name: PLC-gamma binds to the active receptor (Homo sapiens)


name: SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol (Sus scrofa)


name: POFUT2 transfers fucose to TSR domain-containing proteins (Xenopus tropicalis)


name: SFTPD 12mer translocates from ER membrane to extracellular region (Bos taurus)


name: Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol (Rattus norvegicus)


name: cyclo(L-tyrosyl-L-tyrosyl) + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) => mycoclysin + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O


name: L-gamma-glutamyl-L-propargylglycine + ADP + phosphate + H(+) => L-propargylglycine + L-glutamate + ATP


name: dodecanoate + glycerol + H(+) => 1-dodecanoylglycerol + H2O


name: 6-oxohexanoate + NADH + H(+) => 6-hydroxyhexanoate + NAD(+)


name: mRNA8 is translated to protein 8 (Homo sapiens)


name: (12R)-hydroxy-(9Z)-octadecenoate + A + H2O => (9Z)-octadecenoate + AH2 + O2


name: Aquaporin-1 passively transports water into cell (Homo sapiens)


name: an L-alpha-amino acid + L-arginine + ATP <=> L-arginyl-L-alpha-amino acid + ADP + phosphate + H(+)


name: hexanoyl-[ACP] + 7 malonyl-CoA + 6 H(+) => noranthrone + holo-[ACP] + 7 CO2 + 7 CoA + 2 H2O


name: Tachykinin receptor 3 (NK3) binds to neurokinin B (Rattus norvegicus)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP (Mus musculus)


name: cyclin-dependent protein kinase activity


name: melibiose(in) + Na(+)(in) <=> melibiose(out) + Na(+)(out)


name: FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Sus scrofa)


name: p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 (Rattus norvegicus)


name: Degradation of multiubiquitinated Nek2A (Xenopus tropicalis)


name: AAK1 phosphorylates AP-2 mu subunit at T156 (Canis familiaris)


name: (S)-1-phenylethylamine + pyruvate <=> acetophenone + L-alanine


name: L-aspartate + 3 NADPH + 3 O2 + 2 H(+) = 2-nitrobutanedioate + 3 NADP(+) + 4 H2O


name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Saccharomyces cerevisiae)


name: 11cROL binds to RLBP1 to form RLBP1:11cROL (Rattus norvegicus)


name: DHRSX oxidizes polyprenol to polyprenal (Danio rerio)


name: ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans (Bos taurus)


name: Defective MAN1B1 does not hydrolyse 1,2-linked mannose (c branch) (Homo sapiens)


name: CBL binds and ubiquitinates phosphorylated Sprouty (Rattus norvegicus)


name: (2E,6E)-farnesyl diphosphate + H2O = (5S,9S,10S)-drim-7-en-11-ol + diphosphate


name: 1-O-(9Z-octadecenyl)-sn-glycero-3-phosphate + choline + H(+) => 1-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine + H2O


name: a CDP-1,2-diacyl-sn-glycerol + L-serine <=> a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)


name: SLC25A32 transports THF from cytosol to mitochondrial matrix (Sus scrofa)


name: EHMT1:EHMT2 complex binds E2F6.com-1 core (Bos taurus)


name: L-lysyl-[protein] + NAD(+) = N(6)-(ADP-D-ribosyl)-L-lysyl-[protein] + nicotinamide + H(+)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-L-serine + hexadecanoate + H(+) => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + H2O


name: CDK2 phosphorylates RBBP8 (Canis familiaris)


name: IL19 binds IL20RA:JAK1:IL20RB (Mus musculus)


name: phosphoadenylyl-sulfate reductase (thioredoxin) activity


name: 4-hydroxylamino-2,6-dinitrotoluene + 2 NADPH + 2 H(+) => 2,4-dihydroxylamino-6-nitrotoluene + 2 NADP(+) + H2O


name: Expression of TWINKLE (TWNK, PEO1) (Homo sapiens)


name: germacrene A alcohol dehydrogenase activity


name: Phospho-Chico: Activated DINR binds p60:Dp110 (Drosophila melanogaster)


name: PLA2s hydrolyze phospholipids at the Golgi membrane (Sus scrofa)


name: C3a anaphylatoxin binds C3a receptor (Gallus gallus)


name: [Wnt protein]-L-serine + (9Z)-hexadecenoyl-CoA = [Wnt protein]-O-(9Z)-hexadecenoyl-L-serine + CoA


name: "[Wnt protein] O-palmitoleoyl transferase"


name: Calcium Binds Troponin-C (Canis familiaris)


name: RHOD GAPs stimulate RHOD GTPase activity (Canis familiaris)


name: (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + malonyl-CoA + H(+) => 3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + CO2 + CoA


name: PCSK9:LDLR bind to Clathrin (Xenopus tropicalis)


name: chaperone mediated protein folding independent of cofactor


name: histone H4K16 deacetylase activity, hydrolytic mechanism


name: sn-glycero-3-phospho-L-serine + H2O => sn-glycerol 3-phosphate + L-serine + H(+)


name: PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates (Danio rerio)


name: p-T,Y MAPK dimers translocate to nucleus (Schizosaccharomyces pombe)


name: 6-geranylgeranyl-2-methylbenzene-1,4-diol + CO2 + diphosphate => homogentisate + (2E,6E,10E)-geranylgeranyl diphosphate + H(+)


name: SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Mus musculus)


name: p-T774-PKN1 phosphorylates PPP1R14A (Drosophila melanogaster)


name: (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + O2 = (5S)-hydroxy-(15S)-hydroperoxy-(6E,8Z,11Z,13E)-eicosatetraenoate


name: (Z)-4-methylsulfanylbutyl-N-(sulfonatooxy)methanimidothioate + D-glucose => glucoerucin + H2O


name: NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression (Rattus norvegicus)


name: an N-(acyl)-sphingosyl-1,3-cyclic phosphate + ethanolamine => an N-(acyl)-sphingosylphosphoethanolamine


name: S-Farn-Me KRAS4B binds calmodulin (Drosophila melanogaster)


name: DENND1s exchange GTP for GDP on RAB35 (Homo sapiens)


name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Xenopus tropicalis)


name: Binding of STAT1 to p-IFNGR1 (Mus musculus)


name: Parathyroid hormone receptor can bind parathyroid hormone (Mus musculus)


name: L-glutaminyl-tRNA(Gln) + AMP + diphosphate => tRNA(Gln) + L-glutamine + ATP


name: hypoxanthine(in) + Na(+)(in) => hypoxanthine(out) + Na(+)(out)


name: restricticin + H2O => restrictinol + glycine + H(+)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Bos taurus)


name: "phycobiliprotein beta-cysteine-155 phycobilin lyase"


name: L-threonyl-[tau protein] + ATP = O-phospho-L-threonyl-[tau protein] + ADP + H(+)


name: decanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-decenoyl-CoA + reduced [electron-transfer flavoprotein]


name: (3S)-3-hydroxybutanoyl-CoA + NAD(+) => acetoacetyl-CoA + NADH + H(+)


name: Persulfide sulfur is dioxygenated (Rattus norvegicus)


name: 4-ethylphenol + 3'-phosphoadenylyl sulfate => 4-ethylphenyl sulfate + adenosine 3',5'-bisphosphate + H(+)


name: UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Dictyostelium discoideum)


name: 4alpha-carboxy-4beta-methyl-5alpha-cholest-7-ene-3beta-ol + NADP(+) => 4alpha-methyl-5alpha-cholest-7-en-3-one + CO2 + NADPH


name: FNTB inhibitors bind FNTA:FNTB (Bos taurus)


name: Active FLT3 binds to SH2B3 (Homo sapiens)


name: COASY transfers an adenylyl group from ATP to PPANT (Caenorhabditis elegans)


name: Cytosolic folate export across the plasma membrane (Rattus norvegicus)


name: Haptoglobin binds Hemoglobin (Rattus norvegicus)


name: tetradecanoyl-CoA + H2O <=> tetradecanoate + CoA + H(+)


name: 2 oxidized [azurin] + tyramine + H2O => 2 reduced [azurin] + (4-hydroxyphenyl)acetaldehyde + NH4(+) + 2 H(+)


name: down regulation of siderophore biosynthetic process, peptide modification


name: TECR,TECRL dehydrogenate TOD-CoA to ST-CoA (Mus musculus)


name: asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity


name: MAP kinase serine/threonine phosphatase activity


name: Decarboxylation of 5-hydroxytryptophan forms serotonin (Bos taurus)


name: (4R)-limonene + NADH + O2 + H(+) <=> limonene 1,2-epoxide + NAD(+) + H2O


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Gallus gallus)


name: Caspase-mediated cleavage of GAS2 (Mus musculus)


name: dTDP-4-O-demethyl-beta-L-noviose + novobiocic acid => desmethyldescarbamoylnovobiocin + dTDP + H(+)


name: Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Gallus gallus)


name: adenosylcobinamide kinase (ATP-specific) activity


name: TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Canis familiaris)


name: beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)


name: myo-inosose-5 + NADH + H(+) => myo-inositol + NAD(+)


name: [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl)-L-glutamate + ADP + phosphate + H(+) => [amino-group carrier protein]-C-terminal-L-glutamate + L-glutamate + ATP


name: Aquaporin-1 passively transports water out of cell (Xenopus tropicalis)


name: RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL (Saccharomyces cerevisiae)


name: TRPV1 transports Ca2+ from extracellular region to cytosol (Gallus gallus)


name: PXLP-K56-SRR dimer deaminates D-Ser (Caenorhabditis elegans)


name: L-glutamate transmembrane transporter activity


name: (1R,2R,3S,8R,10R,11R,15S,16S)-3-(acetyloxy)-15-[(4R)-4-[(2S)-3,3-dimethyloxiran-2-yl]-1,4-dihydroxybutan-2-yl]-2,7,7,11,16-pentamethyl-5-oxo-6-oxatetracyclo[9.7.0.0(2,8).0(12,16)]octadec-12-en-10-yl acetate + reduced [NADPH--hemoprotein reductase] + O2 => (1R,2R,3S,8R,10R,11R,15S,16S)-3-(acetyloxy)-15-(1-hydroxy-4-oxobutan-2-yl)-2,7,7,11,16-pentamethyl-5-oxo-6-oxatetracyclo[9.7.0.0(2,8).0(12,16)]octadec-12-en-10-yl acetate + 2-methylpropanoate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)


name: PDSS1,2 ligates FPP to IPPP (Sus scrofa)


name: Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Mus musculus)


name: Interaction of ISG15 with NEDD4 and inhibition of Ebola virus budding (Dictyostelium discoideum)


name: HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm (Dictyostelium discoideum)


name: ethanethiol + pyruvate + NH4(+) => S-ethyl-L-cysteine + H2O


name: CYP11B2 oxidises 18HCORST to ALDO (Rattus norvegicus)


name: N-acetyl-D-glucosamine + L-asparagine => N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O


name: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine <=> 2-[(5Z,8Z,11Z,14Z)-eicosatetraenoylamino]ethyl (9Z)-octadecenoate + (9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: SCF(beta-TrCP) ubiquitinates p-GLI1 (Mus musculus)


name: (2E,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + NADPH + H(+) => (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + NADP(+)


name: NOTUM releases Hh-Np:GPC5 from the plasma membrane (Drosophila melanogaster)


name: C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) (Canis familiaris)


name: galactarate + (E)-feruloyl-CoA = 2-O-[(E)-feruloyl]-D-galactarate + CoA


name: DVL2 binds phosphorylated WWTR1 (TAZ) (Caenorhabditis elegans)


name: FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)


name: AKT1S1 (PRAS40) binds mTORC1 (Bos taurus)


name: butanoate(out) + Na(+)(out) = butanoate(in) + Na(+)(in)


name: uridine(20b) in tRNA + NADH + H(+) => 5,6-dihydrouridine(20b) in tRNA + NAD(+)


name: GAA hydrolyzes lysosomal glycogen (Bos taurus)


name: oxaloacetate + NH4(+) => iminosuccinate + H2O


name: (R)-cembrene A + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: YWHAB dimer dissociates from dephosphorylated RAF (Bos taurus)


name: S,S-dimethyl-beta-propiothetin + (6S)-5,6,7,8-tetrahydrofolate <=> 3-(methylsulfanyl)propanoate + (6S)-5-methyl-5,6,7,8-tetrahydrofolate + H(+)


name: CL transports from the ER to the IM (Homo sapiens)


name: Translocation of Vav1 to CD28 (Sus scrofa)


name: double-stranded DNA endonuclease activity


name: DHX9 binds DNA (Dictyostelium discoideum)


name: cyanate + sulfur + 2 Fe(II)-[cytochrome c] + 2 H(+) => thiocyanate + 2 Fe(III)-[cytochrome c] + H2O


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphate + choline + H(+) => 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O


name: pseudouridine + ATP <=> psi-UMP + ADP + H(+)


name: an 11beta-hydroxysteroid + NAD(+) => an 11-oxosteroid + NADH + H(+)


name: Organic Anion Transporting Polypeptide 2B1 Inhibitors


name: Trimerization of HSF1 in the nucleus (Gallus gallus)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Plasmodium falciparum)


name: 4-hydroxy-L-proline(in) + chloride(in) + 2 Na(+)(in) => 4-hydroxy-L-proline(out) + chloride(out) + 2 Na(+)(out)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + H2O <=> S-(9Z,12Z,15Z-octadecatrienoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)


name: Activation of RAC1 by the PXN:CRK complex (Mus musculus)


name: CBL ubiquitinates FRS2 and FGFR3 (Canis familiaris)


name: JAK2 phosphorylation of GHR (Mus musculus)


name: an N-acylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine => an N-acylsphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol


name: (8E,10S,12Z)-10-hydroperoxyoctadeca-8,12-dienoate => (9Z,12Z)-octadecadienoate + O2


name: gamma-L-glutamyl-(2S)-2-aminobutanoate + ADP + phosphate + H(+) => (2S)-2-aminobutanoate + L-glutamate + ATP


name: Interaction of MyoD:E protein with MEF2 (Drosophila melanogaster)


name: p-PKR dimer phosphorylates MAPT (Sus scrofa)


name: FLIP(L) and procaspase-8 form heterodimer (Bos taurus)


name: IL12B:IL12B translocates from ER lumen to the extracellular region (Danio rerio)


name: Decreased Sensory-Somatic Nervous System CCK Activity


name: Phosphorylation of DCC by Fyn (Caenorhabditis elegans)


name: PEX3:PEX19:class I PMP dissociates (Sus scrofa)


name: S-methyl-1-thio-D-xylulose 5-phosphate + glutathione <=> S-(methylsulfanyl)glutathione + 1-deoxy-D-xylulose 5-phosphate


name: thiamine(out) + H(+)(in) <=> thiamine(in) + H(+)(out)


name: Branching and elongation of mother and daughter filaments (Saccharomyces cerevisiae)


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) (Homo sapiens)


name: LIG1 bound to APEX1 and PCNA ligates SSB (Sus scrofa)


name: peroxisome matrix targeting signal-1 binding


name: a 1-hydroxy-3-oxo steroid + A => a steroid 1,3-dione + AH2