name: (4R,7S)-7-isopropyl-4-methyloxepan-2-one + H2O => (3R,6S)-6-hydroxy-3,7-dimethyloctanoate + H(+)


name: RHOG binds effectors at the plasma membrane (Mus musculus)


name: Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer.  (Gallus gallus)


name: an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O => an N-acylethanolamine + a 1,2-diacyl-sn-glycero-3-phosphate + H(+)


name: Association of TFAM:mt promoter complex with POLRMT:TFB2M (Bos taurus)


name: ADK phosphorylates RBV (Dictyostelium discoideum)


name: NT5C2 tetramer dephosphorylates RBV-MP (Gallus gallus)


name: ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity


name: methyl 8-{[alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate + GDP-beta-L-fucose => methyl 8-{[alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc]oxy}nonanoate + GDP + H(+)


name: quercetin 3-sulfate + 3'-phosphoadenylyl sulfate = quercetin 3,3'-bissulfate + adenosine 3',5'-bisphosphate + H(+)


name: a short-chain (3R)-hydroxy fatty acyl-CoA + NAD(+) <=> a short-chain 3-oxoacyl-CoA + NADH + H(+)


name: N-tetracosanoyl-heptadecasphing-4-enine + CoA + H(+) => heptadecasphing-4-enine + tetracosanoyl-CoA


name: EP2 and EP4 receptors can bind PGE2 (Rattus norvegicus)


name: (1S,4S)-4-[(4-hydroxyphenyl)methyl]-2-methyl-2,5-diazaspiro[bicyclo[3.2.1]octane-6,1'-cyclohexan]-4'-one + S-adenosyl-L-methionine = (1S,4S)-4-[(4-methoxyphenyl)methyl]-2-methyl-2,5-diazaspiro[bicyclo[3.2.1]octane-6,1'-cyclohexan]-4'-one + S-adenosyl-L-homocysteine + H(+)


name: 3-oxo-L-alanyl-[sulfatase] + hydrogen sulfide + 5'-deoxyadenosine + L-methionine + 2 H(+) => L-cysteinyl-[sulfatase] + S-adenosyl-L-methionine + H2O


name: Assembly of the retrograde IFT train (Mus musculus)


name: alpha-muricholate + 3'-phosphoadenylyl sulfate => alpha-muricholate 7-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: 2-oxoglutarate(in) + H(+)(in) <=> 2-oxoglutarate(out) + H(+)(out)


name: Phosphorylated REL is cleaved by and dissociates from DREDD in the PGN:PGRP-LC oligomer receptor 'signalling complex' (Drosophila melanogaster)


name: p-S276-RELA binds RELB (Rattus norvegicus)


name: 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate (Caenorhabditis elegans)


name: Prostaglandin E synthase isomerizes PGH2 to PGE2 (Homo sapiens)


name: FUK phosphorylates beta-Fuc to Fuc1P (Caenorhabditis elegans)


name: Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Homo sapiens)


name: (3R)-hydroxyhexanoyl-CoA => (2E)-hexenoyl-CoA + H2O


name: (2E,6E)-farnesyl diphosphate => (3E,6E)-alpha-farnesene + diphosphate


name: 2-(9Z-octadecenoyl)-glycerol + octadecanoyl-CoA => 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CoA


name: a 3-O-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + CMP-N-acetyl-beta-neuraminate => a 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + CMP + H(+)


name: (S)-2-hydroxyglutarate + A => 2-oxoglutarate + AH2


name: CLAT:AP1:CLVS bind PI(3,5)P2 (Xenopus tropicalis)


name: 2 superoxide + a ubiquinone + 2 H(+) => a ubiquinol + 2 O2


name: FAH cleaves 4FAA (Dictyostelium discoideum)


name: GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 (Homo sapiens)


name: Factor H binds to membrane-associated C3b (Canis familiaris)


name: carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+) => hydrogencarbonate + L-glutamine + 2 ATP + H2O


name: triphosphoric monoester hydrolase activity


name: CCNG1 recruits PP2A-PPP2R5C to MDM2 (Xenopus tropicalis)


name: N-hydroxy-L-pentahomomethionine + reduced [NADPH--hemoprotein reductase] + O2 => N,N-dihydroxy-L-pentahomomethionine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: a beta-lactam + H2O => a substituted beta-amino acid


name: RUNX3:CBFB binds the RORC gene promoter (Homo sapiens)


name: GSDMD (1-275) binds bacterial cardiolipin (Bos taurus)


name: L-histidyl-L-alpha-amino acid(out) => L-histidyl-L-alpha-amino acid(in)


name: 12-methyltridecanoyl-CoA + 3 malonyl-CoA + 3 H(+) <=> 4-hydroxy-6-(13-methyl-2-oxotetradecyl)pyran-2-one + 3 CO2 + 4 CoA


name: (2E,6E,10E)-geranylgeranyl diphosphate = beta-pinacene + diphosphate


name: NEDD8:AcM-UBE2M binds CRL2 E3 ubiquitin ligase complex (Canis familiaris)


name: HS3ST1 sulfates GlcN at C3 in heparan sulfate (Drosophila melanogaster)


name: ABCB1,ABCC2 transport ATVs from cytosol to extracellular region (Drosophila melanogaster)


name: (4S)-limonene + A + H2O <=> (4S)-perillyl alcohol + AH2


name: D-serine(out) + H(+)(out) <=> D-serine(in) + H(+)(in)


name: (3R)-hydroxy-(11Z,14Z)-eicosadienoyl-CoA <=> (2E,11Z,14Z)-eicosatrienoyl-CoA + H2O


name: biochanin A 7-O-beta-D-glucoside + malonyl-CoA <=> biochanin A 7-O-beta-D-glucoside 6''-O-malonate + CoA


name: FOLR2 transports FOLA from extracellular region to cytosol (Canis familiaris)


name: pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle (Mus musculus)


name: pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Caenorhabditis elegans)


name: IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Bos taurus)


name: 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2


name: Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter (Bos taurus)


name: mRNA N1-methyladenosine dioxygenase activity


name: I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen (Rattus norvegicus)


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Saccharomyces cerevisiae)


name: 1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H2O = 9-oxononanoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: N-methylmyosmine + H2O <=> pseudooxynicotine


name: 4beta-methylzymosterol-4alpha-carboxylate + NAD(+) => 3-dehydro-4-methylzymosterol + CO2 + NADH


name: D-cellopentaose + O2 <=> D-cellopentaono-1,5-lactone + H2O2


name: 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + 2-oxoglutarate + O2 = 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine(37) in tRNA(Phe) + succinate + CO2


name: Formation of lysino-5-ketonorleucine cross-links (Homo sapiens)


name: N(6)-propanoyl-L-lysyl-[protein] + NAD(+) + H2O <=> 3''-O-propanoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]


name: 7-oxoresolvin D2 + NADH + H(+) => resolvin D2 + NAD(+)


name: 3-hydroxycyclohexanone + A = cyclohexane-1,3-dione + AH2


name: Closure of gap junction (Rattus norvegicus)


name: SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Mus musculus)


name: siamenoside I + UDP-alpha-D-glucose <=> isomogroside V + UDP + H(+)


name: sn-glycerol 3-phosphocholine + 2 hexadecanoate + 2 H(+) => 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + 2 H2O


name: AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Homo sapiens)


name: p-Y705-STAT3 binds p-Y693-STAT4 (Xenopus tropicalis)


name: a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine


name: alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA (Drosophila melanogaster)


name: Proteasomal clevage of exogenous antigen (immunoproteasome catalyst) (Sus scrofa)


name: GDIs block activation of RHOC (Mus musculus)


name: N(6)-carboxybiotinyl-L-lysyl-[protein] + propanoyl-CoA => methylmalonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]


name: methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate + GDP-beta-L-fucose <=> methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate + GDP + H(+)


name: stimulation of tyrosine phosphorylation of Stat3 protein


name: Activated JNKs phosphorylate c-JUN (Caenorhabditis elegans)


name: L-cystine(out) + ATP + H2O = L-cystine(in) + ADP + phosphate + H(+)


name: Assembly of the pre-incision complex in TC-NER (Bos taurus)


name: Phosphorylation of DCC by Fyn (Xenopus tropicalis)


name: isonicotinyl-CoA + L-lysyl-[protein] = N(6)-isonicotinyl-L-lysyl-[protein] + CoA + H(+)


name: 2-hydroxytetracosanoyl-CoA + sphinganine => N-(2-hydroxytetracosanoyl)-sphinganine + CoA + H(+)


name: losartan + UDP-alpha-D-glucuronate => losartan-2-N-beta-D-glucuronide + UDP


name: PGP:Mg2+ dimer hydrolyses G3P to glycerol (Danio rerio)


name: CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Xenopus tropicalis)


name: SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Sus scrofa)


name: (1'S)-averantin + reduced [NADPH--hemoprotein reductase] + O2 = (1'S,5'S)-5'-hydroxyaverantin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Xenopus tropicalis)


name: Cytosolic PLK1 translocates to the nucleus (Sus scrofa)


name: estrone 3-sulfate(in) + ATP + H2O <=> estrone 3-sulfate(out) + ADP + phosphate + H(+)


name: WDR83:LAMTOR2:LAMTOR3 binds MAPK components (Caenorhabditis elegans)


name: isopentenyl diphosphate + dimethylallyl diphosphate = neryl diphosphate + diphosphate


name: Phosphorylated GPNMB recruits PTK6 and LRRK2 in the presence of LINC01139 (Homo sapiens)


name: CTBP1,CTBP2 binds CDH1 gene promoter (Homo sapiens)


name: NFE2L2 dependent ABCF2 expression (Homo sapiens)


name: PNLIP:CLPS hydrolyses RPALM to atROL and PALM (Homo sapiens)


name: NEIL2 cleaves 5-OHU from damaged DNA (Canis familiaris)


name: HCMV Binds Host Cell Receptor - Endocytic Pathway (Homo sapiens)


name: cd-cytochrome nitrite reductase activity


name: SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to UBE2I (Homo sapiens)


name: superoxide-generating NADPH oxidase activity


name: NADPH + 2 O2 = 2 superoxide + NADP(+) + H(+)


name: CARNMT1 methylates CARN to Anserine (Dictyostelium discoideum)


name: eriodictyol-7-O-beta-D-glucoside + H2O <=> (S)-eriodictyol + beta-D-glucose


name: 1-O-dodecylglycerone 3-phosphate + hexadecanoate + H(+) => dodecan-1-ol + 1-hexadecanoylglycerone 3-phosphate


name: Active MTORC1 binds the ULK1 complex (Mus musculus)


name: pseudouridine + ATP = psi-UMP + ADP + H(+)


name: (6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + reduced [NADPH--hemoprotein reductase] + O2 => glyceollin III + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: Phosphoinositide 3-Kinase delta Inhibitors [MoA]


name: CARMA1 recruits MALT1 and BCL10 forming CBM Complex (Rattus norvegicus)


name: RCC1 stimulates GDP to GTP exchange on RAN (Dictyostelium discoideum)


name: L-glutamate 5-semialdehyde + acetyl-CoA = N-acetyl-L-glutamate 5-semialdehyde + CoA + H(+)


name: MAP3K8 is phosphorylated (Gallus gallus)


name: [trehalose-6-phosphate synthase]-L-cysteine + S-adenosyl-L-methionine => [trehalose-6-phosphate synthase]-S-methyl-L-cysteine + S-adenosyl-L-homocysteine + H(+)


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> isoelisabethatriene + diphosphate


name: a 4'-hydroxyisoflavone + S-adenosyl-L-methionine <=> a 4'-methoxyisoflavone + S-adenosyl-L-homocysteine + H(+)


name: PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Homo sapiens)


name: 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylate + NAD(+) = 3-methylcatechol + CO2 + NADH


name: thebaine + S-adenosyl-L-homocysteine + H(+) => oripavine + S-adenosyl-L-methionine


name: Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Gallus gallus)


name: dUTP + 2 H2O <=> dUMP + 2 phosphate + 2 H(+)


name: 3-dehydro-2,22-dideoxyecdysone + 2 reduced [adrenodoxin] + O2 + 2 H(+) => 3-dehydro-2-deoxyecdysone + 2 oxidized [adrenodoxin] + H2O


name: NEK9 phosphorylates NEK6/NEK7 (Sus scrofa)


name: 20-hydroxyecdysone + A + H2O => ecdysone + AH2 + O2


name: Dephosphorylation of p107 (RBL1) by PP2A (Xenopus tropicalis)


name: p-ERK phosphorylates WAVEs and ABI (Gallus gallus)


name: Urotensin-2 receptor binds urotensin-2 and 2B (Homo sapiens)


name: UV-DDB ubiquitinates XPC (Canis familiaris)


name: Formation of MSH1:PMS2 Complex (Drosophila melanogaster)


name: FABP5 dissociates from RXRA:PPARD:atRA (Canis familiaris)


name: α1-agonists bind ADRA1A,B,D (Gallus gallus)


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT (Plasmodium falciparum)


name: N(6)-[(S)-lactoyl]-L-lysyl-[protein] + NAD(+) + H2O <=> 2''-O-(S)-lactoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]


name: an N-acyl-sphingoid base + UDP-alpha-D-galactose => a D-galactosylceramide + UDP + H(+)


name: RPIA isomerizes D-ribulose 5-phosphate to ribose 5-phosphate (Mus musculus)


name: Group 3 - Selective Cl- transport (Mus musculus)


name: N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-asparaginyl-[protein] + UDP + H(+)


name: N(omega)-(1-hydroxy-2-oxopropyl)-L-arginyl-[protein] + H2O => lactate + L-arginyl-[protein] + H(+)


name: 9-decenoyl-CoA + 2 malonyl-CoA + 2 H(+) => 4-hydroxy-6-(non-8-en-1-yl)-pyran-2-one + 2 CO2 + 3 CoA


name: Formation of alternative pathway C5 convertase (Sus scrofa)


name: G6B binds PTPN6,PTPN11 (Canis familiaris)


name: methyl-Co(III)-[corrinoid Fe-S protein] + (6S)-5,6,7,8-tetrahydrofolate <=> Co(I)-[corrinoid Fe-S protein] + (6S)-5-methyl-5,6,7,8-tetrahydrofolate + H(+)


name: thromboxane B2(out) = thromboxane B2(in)


name: Activated FGFR4 phosphorylates PLCG1 (Homo sapiens)


name: TRPs transport extracellular Ca2+ to cytosol (Dictyostelium discoideum)


name: (S)-lactaldehyde + pyruvate => 2-dehydro-3-deoxy-L-fuconate


name: GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol (Mus musculus)


name: 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-(N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl)-L-threonyl-[protein] + UDP + H(+)


name: CCNA:CDK1 phosphorylates OBI1 (Mus musculus)


name: PLK1 phosphorylates NUDC (Rattus norvegicus)


name: (4S)-4-hydroxy-L-glutamate + 2-oxoglutarate => (4R)-4-hydroxy-2-oxoglutarate + L-glutamate


name: steviolbioside + UDP-alpha-D-glucose = stevioside + UDP


name: dTDP-beta-L-rhodosamine + aklavinone <=> aclacinomycin T + dTDP + 2 H(+)


name: Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Homo sapiens)


name: ABCB1 transports PREDN,PREDL out of kidney cells (Homo sapiens)


name: [protein]-disulfide + 2 glutathione = [protein]-dithiol + glutathione disulfide


name: KDM6B binds iron (Caenorhabditis elegans)


name: (2E,6E)-farnesyl diphosphate = (S)-beta-bisabolene + diphosphate


name: 2-amino-2-phenylacetonitrile + 2 H2O + H(+) => D-alpha-phenylglycine + NH4(+)


name: mandelate + O2 = phenylglyoxylate + H2O2


name: regulation of octadecene metabolic process


name: peroxisome targeting signal-1 receptor activity


name: (9Z)-hexadecenoate(out) + ATP(in) + CoA(in) + H(+)(out) = (9Z)-hexadecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) (Dictyostelium discoideum)


name: PKN1:AR complex binds promoters of KLK2 and KLK3 genes (Bos taurus)


name: PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane (Danio rerio)


name: AKT-phosphorylated FOXO1,FOXO3,FOXO4 translocate to the cytosol (Caenorhabditis elegans)


name: YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 (Mus musculus)


name: TEAD2,TEAD4:YAP1, TBXT, FOXH1, and SMAD2,3 bind the FOXA2 gene (Homo sapiens)


name: tryptamine + AH2 + O2 = 4-hydroxytryptamine + A + H2O


name: 24-methylidenelophenol + S-adenosyl-L-methionine = (Z)-24-ethylidenelophenol + S-adenosyl-L-homocysteine + H(+)


name: a fatty acid + ATP <=> a fatty acyl phosphate + ADP


name: RHOD translocates to the Golgi membrane (Mus musculus)


name: mRNA9 is translated to protein 9b (Homo sapiens)


name: N-octadecanoyl-heptadecasphing-4-enine + CoA + H(+) => heptadecasphing-4-enine + octadecanoyl-CoA


name: Activation of Protein Kinase C novel isoforms (Canis familiaris)


name: DFF dissociates from importin-alpha:importin-beta (Rattus norvegicus)


name: an aromatic L-alpha-amino acid(in) + 3,3',5-triiodo-L-thyronine(out) => an aromatic L-alpha-amino acid(out) + 3,3',5-triiodo-L-thyronine(in)


name: ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA (Bos taurus)


name: Formation of the Spliceosomal C complex containing intron lariat (Rattus norvegicus)


name: (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + O2 => (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E)-docosapentaenoate


name: 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate


name: hnu + octadecanoate + H(+) = heptadecane + CO2


name: (R)-reticuline + reduced [NADPH--hemoprotein reductase] + O2 = salutaridine + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: PAK1:ARHGEF6 complex binds G-protein beta-gamma complex (Caenorhabditis elegans)


name: 2-(3-methylsulfanyl)propylmalate = 2-(2-methylsulfanyl)propylmaleate + H2O


name: (1S,4R)-menthone + NADPH + O2 + H(+) => (4S,7R)-7-isopropyl-4-methyloxepan-2-one + NADP(+) + H2O


name: ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs (Caenorhabditis elegans)


name: 2 dopamine + O2 <=> 2 dopamine quinone + 2 H2O


name: a long-chain fatty acyl-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] = a long-chain fatty acyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + H(+)


name: a 1-O-alkyl-sn-glycero-3-phosphoethanolamine + H2O = a 1-O-alkyl-sn-glycero-3-phosphate + ethanolamine + H(+)


name: 3-O-[beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-2-O-P-Xyl]-L-seryl-[protein] + UDP + H(+) => 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-2-O-phosphoxylosyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate


name: FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: positive regulation of metalloenzyme activity


name: dTMP + (6S)-5,6,7,8-tetrahydrofolate + NADP(+) => dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADPH + H(+)


name: MET phosphorylates PTK2 (Rattus norvegicus)


name: (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + NAD(+) + 2 H2O <=> (4S)-4-hydroxy-L-glutamate + NADH + H(+)


name: dGMP + NAD(+) <=> N(2)-(ADP-D-ribosyl)-dGMP + nicotinamide + H(+)


name: (R)-carnitine + ATP + CoA = (R)-carnitinyl-CoA + AMP + diphosphate


name: sphinganine + (9Z)-octadecenoate => N-(9Z-octadecenoyl)-sphinganine + H2O


name: codeine + NADP(+) => codeinone + NADPH + H(+)


name: p-4Y-SIRPA:CD47:SKAP2 binds FYB (Gallus gallus)


name: 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Mus musculus)


name: regulation of ubiquitin protein ligase activity


name: 9alpha-copalyl diphosphate => isopimara-8(14),15-diene + diphosphate


name: (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde = quinolinate + H2O + H(+)


name: Initial activation of proMMP13 by plasmin and trypsin (Gallus gallus)


name: Autoproteolytic cleavage of Hh precursors (Rattus norvegicus)


name: G-protein alpha releases G-protein heterotrimer from PDCL  (Mus musculus)


name: CDP(out) + UTP(in) <=> CDP(in) + UTP(out)


name: Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Homo sapiens)


name: SPOP:CUL3:RBX1 ubiquitinates GLI2,3 (Homo sapiens)


name: NR3C1 binds NR3C1 agonists (Rattus norvegicus)


name: VAV2 is a GEF for Rho/Rac family kinases (Rattus norvegicus)


name: uridine(1498) in 16S rRNA + S-adenosyl-L-methionine <=> N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine + H(+)


name: Journey of cargo through Golgi complex (Gallus gallus)


name: Active G alpha (q) binds RGS proteins (Mus musculus)


name: propanoyl-CoA + H2O => propanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)


name: SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids (Xenopus tropicalis)


name: Association of Emi1 with Cdc20 (Drosophila melanogaster)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 19,20-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter (Rattus norvegicus)


name: activation of peptidyl-cysteine S-palmitoylation


name: NR1D1 (REV-ERBA) binds heme, the CLOCK gene, and recruits corepressors (Homo sapiens)


name: GRB2:GAB1 binds to phosphorylated EGFR (Sus scrofa)


name: (2E,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + NADPH + H(+) <=> (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + NADP(+)


name: methionine and threonine metabolic process


name: nsp13 helicase melts secondary structures in SARS-CoV-1 genomic RNA template (Homo sapiens)


name: 1-propanol + butanoyl-CoA <=> propyl butanoate + CoA


name: L-tyrosine(out) + ATP + H2O = L-tyrosine(in) + ADP + phosphate + H(+)


name: BTK in active Gq-BTK complex is activated (Mus musculus)


name: 4-hydroxybenzaldehyde + NAD(+) + H2O <=> 4-hydroxybenzoate + NADH + 2 H(+)


name: 1-hexadecanoylglycerone 3-phosphate + (9Z)-octadecenoate => 1-(9Z)-octadecenoylglycerone 3-phosphate + hexadecanoate


name: 2-deoxy-D-glucose + ATP = 2-deoxy-D-glucose 6-phosphate + ADP + H(+)


name: dCMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H2O <=> 5-hydroxymethyl-dCMP + (6S)-5,6,7,8-tetrahydrofolate


name: CCNK binds CDK13 (Schizosaccharomyces pombe)


name: hydrogen sulfide + formaldehyde + H2O2 + H(+) => methanethiol + O2 + H2O


name: an N-(34-(9Z,12Z-octadecadienoyloxy)-tetratriacontadienoyl)-sphing-4-enine + a diacylglycerol => an N-(34-hydroxytetratriacontadienoyl)-sphing-4-enine + a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol


name: SGTA binds mislocalized membrane protein (Bos taurus)


name: beta-alanyl-dopamine + H2O <=> dopamine + beta-alanine


name: 4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity


name: MYLIP dimer ubiquitinates VLDLR on Lys-839 (Homo sapiens)


name: ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O


name: USP34 deubiquitinates AXIN1,AXIN2 (Sus scrofa)


name: I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Xenopus tropicalis)


name: USP49 deubiquitinates H2B (Canis familiaris)


name: OPLAH hydrolyses OPRO to L-Glu (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + ADP + H(+) => a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + ATP


name: Active IKK Complex phosphorylates NF-kappa-B inhibitor  (Sus scrofa)


name: Cis-homodimerization of nectins (Xenopus tropicalis)


name: 5,7-dihydroxy-4,6-dimethylphthalide + (2E,6E)-farnesyl diphosphate => (E,E)-farnesyl-5,7-dihydroxy-4,6-dimethylphthalide + diphosphate + H(+)


name: glycocholate + L-arginine = L-arginocholate + glycine


name: 1-heptadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA


name: Nuclear transport of pChREBP (Thr 666) protein (Rattus norvegicus)


name: a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + H2O <=> a 2,3-saturated aldehyde + sn-glycerol 3-phosphocholine


name: pyridoxamine 5'-phosphate + O2 + H2O = pyridoxal 5'-phosphate + H2O2 + NH4(+)


name: USP9X (FAM) binds to ubiquitinated SMAD4 (Bos taurus)


name: Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex  (Gallus gallus)


name: 3-(3,4-dihydroxyphenyl)pyruvate + H2O2 + NH4(+) => D-dopa + O2 + H2O


name: N(pros)-(5'-guanosyl-phosphono)-L-histidyl-[RNA ligase] + a 3'-end 3'-phospho-ribonucleotide-RNA + H(+) = a 3'-terminal ribonucleotide 3'-(5'-diphosphoguanosine)-RNA + L-histidyl-[RNA ligase]


name: SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) (Rattus norvegicus)


name: Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: NEDD4L ubiquitinates SMAD2/3 (Homo sapiens)


name: a 1-acyl-sn-glycero-3-phospho-L-serine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA <=> 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: (2R,3S)-homoisocitrate => cis-homoaconitate + H2O


name: 5-methyl-5,6,7,8-tetrahydromethanopterin + oxidized coenzyme F420-(gamma-L-Glu)(n) + H(+) <=> 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420-(gamma-L-Glu)(n)


name: STAT1,STAT3,STAT6 phosphorylation (Rattus norvegicus)


name: RAB3IP stimulates nucleotide exchange on RAB8A (Gallus gallus)


name: (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + reduced [electron-transfer flavoprotein] => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+)


name: 3,5,3'-triiodothyropyruvate + L-glutamate => 3,3',5-triiodo-L-thyronine + 2-oxoglutarate


name: acyl-lipid omega-(9-4) desaturase activity


name: RPS6KA1-dependent phosphorylation of MITF-M (Caenorhabditis elegans)


name: NaS2 co-transports sulphate and two sodium ions (Rattus norvegicus)


name: 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Schizosaccharomyces pombe)


name: MARK3 phosphorylates MITF-M on S173 (Gallus gallus)


name: Ubiquitinated DVL is degraded by the proteasome (Rattus norvegicus)


name: dehydroepiandrosterone 3-sulfate(out) + succinate(in) => dehydroepiandrosterone 3-sulfate(in) + succinate(out)


name: [(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B = yaequinolone C


name: SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol (Bos taurus)


name: GBF1 recruits ARF:GDP to the Golgi (Drosophila melanogaster)


name: 5-methylcytidine(4447) in 28S rRNA + S-adenosyl-L-homocysteine + H(+) => cytidine(4447) in 28S rRNA + S-adenosyl-L-methionine


name: G alpha (z) in G alpha (z):RGS complex is inactivated (Saccharomyces cerevisiae)


name: dTDP-beta-L-vancosamine + devancoaminyl-vancomycin <=> vancomycin + dTDP + H(+)


name: CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Gallus gallus)


name: 2-oxopentanoate + L-kynurenine <=> L-2-aminopentanoate + kynurenate + H2O


name: negative regulation of C-terminal protein geranylgeranylation


name: progesterone + AH2 + O2 => testosterone acetate + A + H2O


name: Demethylase KDM4C binds KLK2 and KLK3 promoters (Danio rerio)


name: L-lysyl-5'-AMP + holo-[peptidyl-carrier protein] = L-lysyl-[peptidyl-carrier protein] + AMP + H(+)


name: [HPr protein]-L-serine + diphosphate => [HPr protein]-O-phospho-L-serine + phosphate + H(+)


name: (5Z,8Z,11Z)-eicosatrienoate + O2 <=> (12S)-hydroperoxy-(5Z,8Z,10E)-eicosatrienoate


name: hydroxylamine + L-glutamate + ATP = L-glutamine hydroxamate + ADP + phosphate


name: oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Rattus norvegicus)


name: Dimerization of phosphorylated IRF3/IRF7 (Gallus gallus)


name: Mevalonate is phosphorylated to mevalonate-5-phosphate (Schizosaccharomyces pombe)


name: nicotinate + NADP(+) + H2O => 6-hydroxynicotinate + NADPH + H(+)


name: 1-O-(1Z-alkenyl)-2-acetyl-sn-glycero-3-phosphoethanolamine + 1-O-hexadecyl-sn-glycero-3-phosphocholine => 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine


name: 2-oxobutanoate + NADPH + H(+) => (2R)-hydroxybutanoate + NADP(+)


name: ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 (Schizosaccharomyces pombe)


name: Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)


name: GDP-beta-L-galactose + alpha-D-mannose 1-phosphate = beta-L-galactose 1-phosphate + GDP-alpha-D-mannose


name: Defective GYS1 does not transfer glucose to growing glycogen chains (Homo sapiens)


name: Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Sus scrofa)


name: Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS (Canis familiaris)


name: SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Xenopus tropicalis)


name: ADP + 2 phosphate(in) + H(+) => phosphate(out) + ATP + H2O


name: DNA polymerases delta, epsilon or kappa bind the GG-NER site (Schizosaccharomyces pombe)


name: activation of phospholipase C activity by serotonin receptor signaling pathway


name: N(2)-acetyl-L-ornithine + 2-oxoglutarate => N-acetyl-L-glutamate 5-semialdehyde + L-glutamate


name: heptanoyl-CoA + O2 <=> (2E)-heptenoyl-CoA + H2O2


name: epitestosterone + UDP-alpha-D-glucuronate => epitestosterone 17-O-(beta-D-glucuronate) + UDP + H(+)


name: ALOX12 oxidises LTA4 to LXA4 (Dictyostelium discoideum)


name: SOCS3 binds activated PTK6 (Rattus norvegicus)


name: RUNX1 binds PRC1 complexes (Homo sapiens)


name: (E)-ferulate + H2O <=> vanillin + acetate


name: L-histidine(out) + L-tryptophan(in) <=> L-histidine(in) + L-tryptophan(out)


name: WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Gallus gallus)


name: PXLP-K56-SRR dimer deaminates D-Ser (Saccharomyces cerevisiae)


name: Autoproteolysis of DAG1 to alpha and beta chains (Mus musculus)


name: N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+) => L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-methionine


name: triacetin + H2O => diacetylglycerol + acetate + H(+)


name: NF-kappa-B complex is transported from cytosol to nucleus (Canis familiaris)


name: Enolase dimers dehydrates 2PG (Canis familiaris)


name: AACS ligates CoA-SH to ACA, forming ACA-CoA (Mus musculus)


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + GDP-beta-L-fucose = an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP + H(+)


name: LDH tetramer reduces PYR to LACT (Drosophila melanogaster)


name: Cleaved fragments of DFF45 dissociate from  DFF40 (Drosophila melanogaster)


name: 4 PBGs bind to form HMB (Rattus norvegicus)


name: dodecanoyl-CoA + 2 malonyl-CoA + 2 H(+) <=> 4-hydroxy-6-undecylpyran-2-one + 2 CO2 + 3 CoA


name: 6-hydroxymethyl-7,8-dihydropterin + ATP <=> (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H(+)


name: glyoxylate(in) + sulfate(out) <=> glyoxylate(out) + sulfate(in)


name: ADRB2:Catecholamine binds ARRB1, ARRB2 (Bos taurus)


name: STARD10 transports PC from ER membrane to lamellar body membrane (Canis familiaris)


name: CSF3 dimer:2xCSF3R:LYN:JAK1 induces phosphorylation of JAK1 (Homo sapiens)


name: SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Caenorhabditis elegans)


name: 4alpha-carboxyzymosterol + NAD(+) <=> zymosterone + CO2 + NADH


name: inhibition of UPR signaling by IRE1 stress sensor


name: SARS-CoV-2 9b binds IKBKG (Homo sapiens)


name: a 12-oxojasmonyl-L-alpha-amino acid + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+) => a 12-hydroxyjasmonyl-L-alpha-amino acid + reduced [NADPH--hemoprotein reductase] + O2


name: (R)-dihydrolipoamide + acetyl-CoA = (R)-S(6)-acetyldihydrolipoamide + CoA


name: quercetin + S-adenosyl-L-methionine => isorhamnetin + S-adenosyl-L-homocysteine + H(+)


name: [pyruvate, water dikinase] + ADP => [pyruvate, water dikinase]-phosphate + AMP + H(+)


name: NMT1/2 transfer MYS to GNAT1 (Saccharomyces cerevisiae)


name: 3'-dehydrocarminate + H(+) => kermesate + 1,5-anhydro-D-erythro-hex-1-en-3-ulose


name: Beta-tubulin:GTP + Cofactor A ->  Beta-tubulin:GTP: Cofactor A (Homo sapiens)


name: (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-glycerate + GDP + H(+) => (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + GDP-alpha-D-mannose


name: 4alpha-hydroxymethyl-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O => (Z)-24-ethylidenelophenol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+)


name: 3-oxo-(13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA + CO2 + CoA => (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + malonyl-CoA + H(+)


name: 1-(9Z,12Z,15Z)-octadecatrienoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z,12Z,15Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: The ligand trap binds the ligand BMP2, blocking BMP signalling (Danio rerio)


name: Frataxin binds iron (Dictyostelium discoideum)


name: fumonisin B1 + hexacosanoyl-CoA => N-(hexacosanoyl)-fumonisin B1 + CoA + H(+)


name: LRAT esterifies RBP1:atROL and FACYLs to atREs (Bos taurus)


name: FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX (Danio rerio)


name: CTSL1 cleaves proHPSE (Rattus norvegicus)


name: SLC26A3,6 exchange Cl- for HCO3- (Caenorhabditis elegans)


name: heptanedioate(in) + 2-oxoglutarate(out) = heptanedioate(out) + 2-oxoglutarate(in)


name: PAK1-3 autophosphorylates (Mus musculus)


name: AMP binds to gamma subunit of AMP kinase heterotrimer (Schizosaccharomyces pombe)


name: androst-5-en-3beta,17beta-diol + NAD(+) = 3beta-hydroxyandrost-5-en-17-one + NADH + H(+)


name: Increased Brain Stem Epinephrine Activity


name: Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175) (Sus scrofa)


name: N(1)-acetylspermidine + 3-aminopropanal + H2O2 => N(1)-acetylspermine + O2 + H2O


name: thebaine + 2-oxoglutarate + O2 <=> oripavine + formaldehyde + succinate + CO2


name: an 11,12-saturated fatty acyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => an (11Z)-Delta(11)-fatty acyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 2',2'-dihydroxy-2-oxospirilloxanthin => 2,2'-dioxospirilloxanthin + H2O


name: Regeneration of eEF1A:GTP by eEF1B activity (Canis familiaris)


name: [protein]-C-terminal Gly-Gly + ATP + H(+) <=> [protein]-C-terminal Gly-Gly-AMP + diphosphate


name: 11-cis-retinyl hexadecanoate + H2O => 11-cis-retinol + hexadecanoate + H(+)


name: N-octadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O <=> N-octadecanoyl ethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+)


name: maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) (Bos taurus)


name: L-arginocholate + H2O => cholate + L-arginine


name: L-lysyl(9)-[histone H3] + 2 S-adenosyl-L-methionine <=> N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + 2 S-adenosyl-L-homocysteine + 2 H(+)


name: Acidification of Tf:TfR1 containing endosome (Dictyostelium discoideum)


name: L-quinate + NAD(+) <=> 3-dehydroquinate + NADH + H(+)


name: acetoin + NH4(+) + NADPH + H(+) => 3-aminobutan-2-ol + NADP(+) + H2O


name: CANX binds Glu1Man9GlcNAc2-CDH1 (Sus scrofa)


name: Association of HMGB1/HMGB2 with chromatin (Drosophila melanogaster)


name: hancockiamide G + acetyl-CoA => hancockiamide C + CoA + H(+)


name: RAC1 GDIs block activation of RAC1 (Caenorhabditis elegans)


name: a short-chain (3R)-hydroxy fatty acyl-CoA <=> a short-chain (2E)-enoyl-CoA + H2O


name: JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Bos taurus)


name: a quinone + hydrogen sulfide + sulfite + 2 H(+) <=> thiosulfate + a quinol


name: FGFR signaling pathway involved in type I programmed cell death


name: Defective TCII does not bind Cbl in the circulation (Homo sapiens)


name: MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG (Canis familiaris)


name: Release of platelet cytosolic components (Bos taurus)


name: 3-nitrobenzaldehyde + NAD(+) + H2O = 3-nitrobenzoate + NADH + 2 H(+)


name: estrone 3-O-(beta-D-glucuronate) + UDP + H(+) => estrone + UDP-alpha-D-glucuronate


name: methyl benzoate + S-adenosyl-L-homocysteine => benzoate + S-adenosyl-L-methionine


name: a 1,2-diacyl-sn-glycerol(in) => a 1,2-diacyl-sn-glycerol(out)


name: VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane (Homo sapiens)


name: D-alanine(out) + L-alanine(in) <=> D-alanine(in) + L-alanine(out)


name: S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 (Sus scrofa)


name: XYLB phosphorylates D-xylulose (Drosophila melanogaster)


name: pseudouridine(1248) in human 18S rRNA + S-adenosyl-L-methionine <=> N(1)-methylpseudouridine(1248) in human 18S rRNA + S-adenosyl-L-homocysteine + H(+)


name: PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Plasmodium falciparum)


name: (+)-lariciresinol + NADPH + H(+) => (-)-secoisolariciresinol + NADP(+)


name: SPINK5(490-624) binds KLK5 (Homo sapiens)


name: Kinesin-5 is a homotetramer (Canis familiaris)


name: hexadecanoyl-AMP + holo-[ACP] <=> hexadecanoyl-[ACP] + AMP + H(+)


name: Binding of Gbeta/gamma to GIRK/Kir3 channels (Sus scrofa)


name: alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + dTDP-beta-L-rhamnose = alpha-L-Rha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + dTDP + H(+)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR3 (Canis familiaris)


name: CYP8B1 12-hydroxylates 4CHOL7a,27DONE (Mus musculus)


name: F-actin capping protein is a heterodimer (Plasmodium falciparum)


name: Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Sus scrofa)


name: octanoylglycerol + octanoate + H(+) => dioctanoylglycerol + H2O


name: Fusion of late-endosome derived vesicles at the TGN (Homo sapiens)


name: 1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA => 1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: Transfer of SUMO1 from E1 to UBE2I (UBC9) (Schizosaccharomyces pombe)


name: (3R)-3-amino-3-phenylpropanoyl-CoA + baccatin III = 3'-N-debenzoyl-2'-deoxytaxol + CoA


name: SOX2 binds the MITF promoter (Homo sapiens)


name: B3GALTL transfers glucose to O-fucosyl-proteins (Bos taurus)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Drosophila melanogaster)


name: PE is methylated to PC by PEMT (Rattus norvegicus)


name: FAR2 reduces PalmCoA to HXOL (Rattus norvegicus)


name: D-xylulose 5-phosphate + formaldehyde <=> dihydroxyacetone + D-glyceraldehyde 3-phosphate


name: P2Y6 receptor can bind to UDP (Rattus norvegicus)


name: 2-acyl LPS is acylated to PS by LPSAT (Mus musculus)


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Xenopus tropicalis)


name: CDP-DAG is converted to PI by CDIPT (Homo sapiens)


name: p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Plasmodium falciparum)


name: Formation of Elongin BC complex (Drosophila melanogaster)


name: 3,5,7,9,11,13-hexaoxotetradecanoyl-[ACP] + 6 CO2 + 7 CoA => holo-[ACP] + 6 malonyl-CoA + acetyl-CoA + 6 H(+)


name: (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + O2 + H(+) => 4-[(E)-2-isocyanoethenyl]phenol + succinate + 2 CO2 + H2O


name: novobiocin(in) + H(+)(out) = novobiocin(out) + H(+)(in)


name: S-sulfanylglutathione + a quinol => a quinone + hydrogen sulfide + glutathione + H(+)


name: DCC interaction with Netrin-1 (Xenopus tropicalis)


name: spermine + O2 + H2O => N-(3-aminopropyl)-4-aminobutanal + propane-1,3-diamine + H2O2


name: a neolactoside III(3)-alpha-Fuc-nLc6Cer(d18:1(4E)) + GDP + H(+) => a neolactoside nLc6Cer(d18:1(4E)) + GDP-beta-L-fucose


name: apoTF binds 2Fe3+ to form holoTF (Bos taurus)


name: trans-3-hydroxy-L-prolyl-[collagen] + succinate + CO2 => L-prolyl-[collagen] + 2-oxoglutarate + O2


name: 2'-deoxyinosine + phosphate => dIMP + H2O


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + ATP <=> 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)


name: FOXG1 binds FOXO:SMAD complexes (Gallus gallus)


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Dictyostelium discoideum)


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Gallus gallus)


name: (13S,14R)-1,13-dihydroxy-N-methylcanadine + acetyl-CoA <=> (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + CoA


name: PHF8 demethylates histone H4K20me1 (Drosophila melanogaster)


name: N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate (Canis familiaris)


name: Association of procollagen type V (Bos taurus)


name: (9Z,12Z,15Z)-octadecatrienoate + H2O <=> (10S)-hydroxy-(12Z,15Z)-octadecadienoate


name: (Z)-phenyl-N-(sulfonatooxy)methanimidothioate = benzyl thiocyanate + sulfate


name: (S)-2-amino-6-oxohexanoate + AMP + diphosphate + NADP(+) <=> L-2-aminoadipate + ATP + NADPH + H(+)


name: Dimerization of LIMK1 by Hsp90 (Dictyostelium discoideum)


name: purine nucleotide-sugar transmembrane transporter activity


name: NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ (Schizosaccharomyces pombe)


name: TCN1 binds correnoids in the circulation (Drosophila melanogaster)


name: chenodeoxycholate + reduced [NADPH--hemoprotein reductase] + O2 = alpha-muricholate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: D-isoleucine(in) + D-serine(out) => D-isoleucine(out) + D-serine(in)


name: SUMOylation of TOPORS with SUMO1 (Sus scrofa)


name: SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Rattus norvegicus)


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-L-alanine + O2 <=> N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-alanine


name: crenolanib-resistant FLT3 mutants don't bind crenolanib (Homo sapiens)


name: 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ (Mus musculus)


name: NTPDase1 hydrolyzes nucleoside diphosphates (Xenopus tropicalis)


name: MSH2 variant:MSH6-defective DNA mismatch repair (Homo sapiens)


name: an N-acyl-sphingoid base + UDP-alpha-D-galactose <=> a D-galactosylceramide + UDP + H(+)


name: 24-methylenecholesterol + UDP-alpha-D-glucose => 24-methylene cholesteryl beta-D-glucoside + UDP + H(+)


name: TNFRSF18 (GITR) gene expression is stimulated by FOXP3 and inhibited by RUNX1 (Homo sapiens)


name: RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate


name: UNC119B stimulates translocation of myristoylated ciliary cargo to the primary cilium (Canis familiaris)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Bos taurus)


name: Activated PKC phosphorylates SHC1 (Homo sapiens)


name: CTNNB1 dissociates from CDH11 upon ANGPTL4 binding (Bos taurus)


name: Production of AA by iPLA2 upon FCGR activation (Drosophila melanogaster)


name: TRIAP1 binds PRELID1, PRELID3A (Plasmodium falciparum)


name: (5S)-albaflavenol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) => albaflavenone + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O


name: I-Smad competes with R-Smad1/5/8 for type I receptor (Mus musculus)


name: L-aspartate transmembrane transporter activity


name: andiconine + NADPH + O2 + H(+) => andilesin D + NADP(+) + H2O


name: G protein binds CX3CR1 on host cell surface (Homo sapiens)


name: Phosphorylation of WWTR1 (TAZ) by LATS2 (Caenorhabditis elegans)


name: NUDT8 hydrolyzes CoA-SH to PPANT (Homo sapiens)


name: PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr (Rattus norvegicus)


name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP (Homo sapiens)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Danio rerio)


name: E2F6:TFDP1 binds EPC1 (Canis familiaris)


name: B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain (Rattus norvegicus)


name: ent-(12E)-labda-8(17),12,14-triene + diphosphate => ent-copalyl diphosphate


name: magnesium-translocating P-type ATPase activity


name: 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Xenopus tropicalis)


name: PRKDC phosphorylates DCLRE1C at DNA DSBs (Gallus gallus)


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + diphosphate => 5-amino-4-imidazolecarboxyamide + 5-phospho-alpha-D-ribose 1-diphosphate


name: ME1 tetramer decarboxylates OA to PYR (Bos taurus)


name: DAAM1 recruits GTP-bound RHOA (Canis familiaris)


name: (S)-1-phenylethylamine + pyruvate = acetophenone + L-alanine


name: MCM2 binds MCM4:MCM6:MCM7 heterotrimer (Schizosaccharomyces pombe)


name: 3-O-[beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-2-O-P-Xyl]-L-seryl-[protein] + H2O => 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + phosphate


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O <=> 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + (9Z)-octadecenoate + H(+)


name: glycerol + phosphate => glycerol 2-phosphate + H2O


name: HIF1A,EPAS1 bind PTK6 gene (Homo sapiens)


name: L-kynurenine transmembrane transporter activity


name: Assembly of the destruction complex (Bos taurus)


name: (2R)-3-phosphoglycerate + H2O <=> (R)-glycerate + phosphate


name: 2-hydroxy-17beta-estradiol + UDP-alpha-D-glucuronate = 2-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronate) + UDP + H(+)


name: 1,2-dibutyryl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate => 1,2-dibutyryl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O


name: (R)-styrene oxide + H2O => (R)-styrene glycol


name: RAB1:GTP recruits GBF1 to the ERGIC (Drosophila melanogaster)


name: Putrescine + dc-Adenosyl methionine  => Spermidine + 5'-methylthioadenosine (Homo sapiens)


name: xylitol + NAD(+) = L-xylulose + NADH + H(+)


name: 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 A = 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 8 AH2


name: Beta-catenin recruits CBP/p300 (Sus scrofa)


name: isoorientin + S-adenosyl-L-methionine => isoscoparin + S-adenosyl-L-homocysteine + H(+)


name: folate(in) + H(+)(in) <=> folate(out) + H(+)(out)


name: DNA polymerases delta, epsilon or kappa bind the TC-NER site (Xenopus tropicalis)


name: beta-D-GalNAc-(1->4)-alpha-L-IdoA-(1->3)-beta-D-GalNAc-4-sulfate-(1->4)-alpha-L-IdoA-(1->3)-D-GalNAc-4-sulfate + H2O => alpha-L-IdoA-(1->3)-beta-D-GalNAc-4-sulfate-(1->4)-alpha-L-IdoA-(1->3)-D-GalNAc-4-sulfate + N-acetyl-D-galactosamine


name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane (Drosophila melanogaster)


name: N(6)-methyl-L-lysyl(27)-[histone H3] + S-adenosyl-L-homocysteine + H(+) => L-lysyl(27)-[histone H3] + S-adenosyl-L-methionine


name: L-cysteinyl-[PqsD protein] + anthraniloyl-CoA = S-anthraniloyl-L-cysteinyl-[PqsD protein] + CoA


name: (S)-columbianetin + reduced [NADPH--hemoprotein reductase] + O2 = angelicin + acetone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: FDPS dimer transfers IPPP to GPP (Dictyostelium discoideum)


name: Active ALK phosphorylates JAK3 (Mus musculus)


name: uridine 2'-phosphate + H(+) => 2',3'-cyclophospho-UMP + H2O


name: A4GALT transfers galactose to LacCer (Homo sapiens)


name: (2E)-geraniol + NADP(+) <=> (2E)-geranial + NADPH + H(+)


name: 4-hydroxybenzaldehyde + formaldehyde => 4-vinylphenol + O2


name: NEIL3 cleaves 5-guanidinohydantoin (Rattus norvegicus)


name: N(6),N(6)-dimethyl-L-lysyl-[protein] + formaldehyde + succinate + CO2 => N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 2-oxoglutarate + O2


name: NADPH oxidase 2 generates superoxide from oxygen (Rattus norvegicus)


name: snRNP:Snurportin complex formation (Rattus norvegicus)


name: Addition of Nucleotides 5 through 9 on the growing Transcript (Drosophila melanogaster)


name: N-methylputrescine + O2 + H2O <=> 4-methylaminobutanal + H2O2 + NH4(+)


name: CCND3,(CCND1,CCND2) binds RUNX1 (Sus scrofa)


name: Interleukin-12 binds Interleukin-12 receptor (Bos taurus)


name: p-STAT1,p-STAT3 dissociate from IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, p-STAT3 (Homo sapiens)


name: N(4)-{alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlaNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,2) + H2O <=> N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B2) + beta-D-mannose


name: 2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + NADPH + H(+)


name: 3'-dehydrocarminate + H(+) = kermesate + 1,5-anhydro-D-erythro-hex-1-en-3-ulose


name: RAC2 GAPs stimulate RAC2 GTPase activity (Rattus norvegicus)


name: a 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol = a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol


name: Granzyme-B activates BID by cleavage (Gallus gallus)


name: CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene  (Sus scrofa)


name: WWTR1 binds SMAD2/3:SMAD4 heterotrimer (Homo sapiens)


name: D-ribose 5-phosphate + H2O <=> D-ribose + phosphate


name: 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Sus scrofa)


name: 1-propanol + acetyl-CoA <=> propyl acetate + CoA


name: 1,4-benzoquinone + NADPH + H(+) = hydroquinone + NADP(+)


name: DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)


name: N-tetracosanoylsphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = N-tetracosanoyl-(4R)-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O


name: Activated FGFR1 binds SHC1 (Drosophila melanogaster)


name: GDP-alpha-D-rhamnose + NADP(+) <=> GDP-4-dehydro-alpha-D-rhamnose + NADPH + H(+)


name: an all-trans-retinyl ester + a 2-acyl-sn-glycero-3-phosphocholine => all-trans-retinol + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: S-sulfanyl-L-cysteinyl-[protein] + pyruvate => 2-oxo-3-sulfanylpropanoate + L-cysteinyl-[protein]


name: CDH1 forms cis-clusters (Xenopus tropicalis)


name: PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Drosophila melanogaster)


name: TLR4:LY96:LPS:CD14 recruits TRAM (TICAM2) (Bos taurus)


name: Polyubiquitinated NRIF migrates to the nucleus (Canis familiaris)


name: SUMOylation of NOP58 with SUMO2 (Drosophila melanogaster)


name: Transphosphorylation of pLIMK1 (Sus scrofa)


name: 4-hydroxybutanoate + ATP + CoA = 4-hydroxybutanoyl-CoA + AMP + diphosphate


name: AKT1 phosphorylates NOTCH4 (Homo sapiens)


name: RBP3 regulates atROL taken up by Muller cells (Canis familiaris)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Dictyostelium discoideum)


name: an N(1)-ethyl-2'-deoxyadenosine in single-stranded DNA + 2-oxoglutarate + O2 <=> a 2'-deoxyadenosine in single-stranded DNA + acetaldehyde + succinate + CO2 + H(+)


name: (6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP <=> (6R)-5,10-methenyltetrahydrofolate + ADP + phosphate


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CTP + H(+) = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate


name: UMP(out) + UDP-N-acetyl-alpha-D-glucosamine(in) = UMP(in) + UDP-N-acetyl-alpha-D-glucosamine(out)


name: SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Rattus norvegicus)


name: HSF1-mediated gene expression (Drosophila melanogaster)


name: 5-PP-IP4 transports from the nucleus to the cytosol (Bos taurus)


name: SFKs phosphorylates RAF1 on Y340,Y341 (Caenorhabditis elegans)


name: Thrombin-activated PARs activate G12/13 (Homo sapiens)


name: a flavanone + 2-oxoglutarate + O2 <=> a flavone + succinate + CO2 + H2O


name: an S-acyl-L-cysteinyl-[protein] + CoA => L-cysteinyl-[protein] + an acyl-CoA


name: Formation of Cyclin A:Cdk2 complexes (Rattus norvegicus)


name: cis-trans-nepetalactol => (S)-8-oxocitronellyl enol


name: 17,18-epoxy-17-hydroxycur-19-ene + acetyl-CoA => diaboline + CoA


name: L-arginyl-[protein] + NAD(+) = ADP-riboxanated L-argininyl-[protein] + nicotinamide + NH4(+) + H(+)


name: CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Bos taurus)


name: down regulation of 1-octadecene biosynthetic process


name: Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling (Drosophila melanogaster)


name: guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine (Danio rerio)


name: NCAM1 cis-homophilic interaction (Homo sapiens)


name: pentalenolactone D + 2 2-oxoglutarate + 2 O2 <=> pentalenolactone F + 2 succinate + 2 CO2 + H2O


name: alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 (Bos taurus)


name: UXS1 tetramer decarboxylates UDP-glucuronate to UDP-xylose (Danio rerio)


name: PP2A methylation by LCMT1 (Rattus norvegicus)


name: PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2 (Homo sapiens)


name: PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters (Saccharomyces cerevisiae)


name: AGMO cleaves alkylglycerol into fatty aldehyde and glycerol (Mus musculus)


name: p-4Y-SIRPA:CD47 binds PTK2B (Homo sapiens)


name: PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)


name: (Z)-phenyl-N-(sulfonatooxy)methanimidothioate = benzyl isothiocyanate + sulfate


name: presqualene phosphate + H2O => presqualene alcohol + phosphate


name: Activation of p38 MAPK (Dictyostelium discoideum)


name: RAN stimulates fusion of nuclear envelope (NE) membranes (Mus musculus)


name: p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Bos taurus)


name: (2E,23Z,26Z,29Z,32Z,35Z)-octatriacontahexaenoyl-CoA + NADPH + H(+) => (23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA + NADP(+)


name: XDH oxidizes hypoxanthine to form xanthine (Rattus norvegicus)


name: a 2'-deoxyuridine in single-stranded DNA + H2O <=> a 2'-deoxyribose 5'-monophosphate in single-stranded DNA + uracil


name: RHOV binds GTP (Saccharomyces cerevisiae)


name: choline sulfate + H2O <=> choline + sulfate + H(+)


name: TMEM55B translocates to the nucleus (Danio rerio)


name: quercetin 3-O-beta-D-glucoside + UDP-beta-L-rhamnose = quercetin 3-O-beta-D-glucoside-7-O-alpha-L-rhamnoside + UDP + H(+)


name: (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Sus scrofa)


name: (+)-pinoresinol + 2 oxidized [azurin] + H2O = (+)-6-hydroxypinoresinol + 2 reduced [azurin] + 2 H(+)


name: Activation of RAC1 by VAV (Gallus gallus)


name: PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Rattus norvegicus)


name: taurocholate + NAD(+) <=> 7-oxo-taurodeoxycholate + NADH + H(+)


name: AURKA phosphorylates PHLDA1 (Homo sapiens)


name: (8Z,11Z,14Z)-eicosatrienoyl-CoA + malonyl-CoA + H(+) => 3-oxo-(10Z,13Z,16Z)-docosatrienoyl-CoA + CO2 + CoA


name: 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: 1-tetracosanoylglycerol + H2O = tetracosanoate + glycerol + H(+)


name: N-acetylneuraminate + acetate + H(+) => N-acetyl-9-O-acetylneuraminate + H2O


name: 3',5'-cyclic diguanylic acid metabolic process


name: D-threo-isocitrate + (E)-caffeoyl-CoA => 2-[(E)-caffeoyl]-D-threo-isocitrate(3-) + CoA


name: (4E,15E)-bilirubin IXalpha C8-beta-D-glucuronoside(out) <=> (4E,15E)-bilirubin IXalpha C8-beta-D-glucuronoside(in)


name: (R)-2-methyl-3-oxopropanoate + NAD(+) + CoA + H2O <=> propanoyl-CoA + hydrogencarbonate + NADH + H(+)


name: malate + 6 malonyl-CoA + acetyl-CoA + 2 AH2 + 2 S-adenosyl-L-methionine + 5 NADPH + 9 H(+) => trihazone A + 2 A + 2 S-adenosyl-L-homocysteine + 6 CO2 + 5 NADP(+) + 7 CoA + 6 H2O


name: 2-methylpropanoyl-CoA + NADH + H(+) => 2-methylpropanal + NAD(+) + CoA


name: CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 (Dictyostelium discoideum)


name: pyochelin biosynthetic process, peptide formation


name: Transport (influx) of bile salts and acids by OATP-A (Gallus gallus)


name: Antigen bound antibody interacts with C1complement complex (Gallus gallus)


name: (R)-salsolinol + S-adenosyl-L-methionine = N-methyl-(R)-salsolinol + S-adenosyl-L-homocysteine + H(+)


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + octadecanoyl-CoA = 1'-[1-acyl-2-octadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: Small molecule inhibitor binds RIPK1, RIPK3 (Canis familiaris)


name: 1-aci-nitro-2-(phenyl)ethane + glutathione <=> (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate + H2O


name: chenodeoxycholate + NAD(+) => 7-oxolithocholate + NADH + H(+)


name: MGST trimers transfer GS from GSH to AFXBO and AFNBO (Homo sapiens)


name: kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Canis familiaris)


name: S-Farn-Me KRAS4B binds calmodulin (Canis familiaris)


name: inhibition of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway


name: D-ribose + nicotinamide + H(+) => beta-nicotinamide D-riboside + H2O


name: 4-nitrobenzaldehyde + NADPH + H(+) = 4-nitrobenzyl alcohol + NADP(+)


name: POM121 and NDC1 bind the Nup93 complex (Sus scrofa)


name: AcK-NFE2L2 binds the NOTCH1 gene (Homo sapiens)


name: ABCC5 transports TPMP substrates from cytosol to extracellular region (Danio rerio)


name: Association of procollagen type XXI (Caenorhabditis elegans)


name: 3-deoxyglucosone + NADPH + H(+) => 3-deoxyfructose + NADP(+)


name: SUMOylation of TOP2A with SUMO1 (Plasmodium falciparum)


name: Vamp2 associated secretory vesicle to plasma membrane transport (Sus scrofa)


name: Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 (Mus musculus)


name: EBI3:CANX binds IL12A (Canis familiaris)


name: activation of stress-activated protein kinase signaling pathway


name: IL37(?-218):p-S423,S425-SMAD3 translocates to the nucleus (Canis familiaris)


name: HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Homo sapiens)


name: catechol + O2 = (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + H(+)


name: inhibition of cytoplasmic protein tyrosine kinase activity


name: (d)AMP + ATP <=> (d)ADP + ADP (AK1) (Mus musculus)


name: RHOG translocates to the ER membrane (Dictyostelium discoideum)


name: Binding of IRS to insulin receptor (Sus scrofa)


name: beta-muricholoyl-CoA + lithocholate => beta-muricholate + lithocholoyl-CoA


name: Aquaporins passively transport water into cells (Plasmodium falciparum)


name: SUMOylation of TDG with SUMO2,3 (Sus scrofa)


name: L-aspartyl-tRNA(Asp) + AMP + diphosphate => tRNA(Asp) + L-aspartate + ATP


name: RNF146 polyubiquitinates PARylated PTEN (Mus musculus)


name: UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-galactose + 2-oxoglutarate + ATP => UDP-yelosamine + ADP + phosphate + H(+)


name: (S)-nicotine + A + H2O <=> (S)-6-hydroxynicotine + AH2


name: dalnigrein beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside + H2O = dalnigrein + beta-D-apiofuranosyl-(1->6)-D-glucopyranose + H(+)


name: (1S,5S)-beta-pinene + diphosphate => (2E)-geranyl diphosphate


name: malvidin 3-O-beta-D-glucoside + UDP => malvidin + UDP-alpha-D-glucose


name: Defective MGAT2 does not transfer GlcNAc to N-glycans (Homo sapiens)


name: ERBB4s80:STAT5A binds CSN2 gene promoter (Homo sapiens)


name: Thrombin-activated PARs activate Gq (Rattus norvegicus)


name: SUMOylation of EP300 with SUMO1 (Sus scrofa)


name: GDP-D-glucose + (2R)-3-phosphoglycerate <=> (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + GDP + H(+)


name: CA4:Zn2+ hydrates CO2 to HCO3- (Xenopus tropicalis)


name: cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + methylcob(III)alamin + S-adenosyl-L-methionine => cytidine 5'-({hydroxy[(S)-2-hydroxypropyl]phosphonoyl}phosphate) + cob(III)alamin + 5'-deoxyadenosine + L-methionine


name: Formation of the PINCH-ILK-parvin complex (Bos taurus)


name: Photons induce isomerisation of 11c-retinyl to at-retinyl (Canis familiaris)


name: Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 (Danio rerio)


name: medium-chain fatty acyl-CoA oxidase activity


name: a medium-chain 2,3-saturated fatty acyl-CoA + O2 = a medium-chain (2E)-enoyl-CoA + H2O2


name: Dual mechanism MAP2K inhibitors bind MAP2Ks (Mus musculus)


name: Recognition and Binding of Core Promoter Elements by TFIID (Canis familiaris)


name: PLA2G15 hydrolyses LPC to GPCho and LCFA(-) (Caenorhabditis elegans)


name: Type B histone acetlytransferase complex acetylates histone H4 (Homo sapiens)


name: S-benzyl-L-cysteinylglycine + H2O <=> S-benzyl-L-cysteine + glycine


name: NEU4 hydrolyses Neu5Ac from glycoconjugates (Bos taurus)


name: L-mimosine <=> 3-hydroxy-4H-pyrid-4-one + 2-aminoprop-2-enoate


name: p-S207 KARS1 dimer binds MITF-M:HINT1 dimer (Canis familiaris)


name: WWTR1 (TAZ) binds ZO-2 (TJP2) (Homo sapiens)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Bos taurus)


name: 4-hydroxyestrone + UDP-alpha-D-glucuronate <=> 4-hydroxyestrone 3-O-(beta-D-glucuronate) + UDP + H(+)


name: SCF:FBXL7 binds AURKA (Xenopus tropicalis)


name: pS181-S-Farn-Me KRAS4B binds BCL2L1 (Caenorhabditis elegans)


name: Activation of Protein Kinase C novel isoforms (Dictyostelium discoideum)


name: BPI binds LPS on the bacterial surface (Xenopus tropicalis)


name: inhibition of naphtho-gamma-pyrone biosynthetic process


name: Transfer of NEDD8 to AcM-UBE2M (Plasmodium falciparum)


name: PM20D1 hydrolyzes oleoyl-phe (Homo sapiens)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O = 1,2-dihexadecanoyl-sn-glycerol + phosphoethanolamine + H(+)


name: 2 formate + 2 oxidized [2Fe-2S]-[ferredoxin] + NAD(+) <=> 2 reduced [2Fe-2S]-[ferredoxin] + 2 CO2 + NADH + H(+)


name: gibberellin A20 + S-adenosyl-L-methionine => gibberellin A20 methyl ester + S-adenosyl-L-homocysteine


name: [translation elongation factor 2] + ATP = [translation elongation factor 2]-phosphate + ADP + H(+)


name: N-[(R)-4-phosphopantothenoyl]-L-cysteine + H(+) <=> (R)-4'-phosphopantetheine + CO2


name: Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Sus scrofa)


name: tetrahydroalstonine + reduced [NADPH--hemoprotein reductase] + O2 <=> dihydroalstonine + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: methyl-Co(III)-[dimethylamine-specific corrinoid protein] + coenzyme M <=> Co(I)-[dimethylamine-specific corrinoid protein] + methyl-coenzyme M + H(+)


name: 8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d + methanol + CO2 => chlorophyllide a + H2O + H(+)


name: caffeine + NADH + O2 + H(+) <=> theobromine + formaldehyde + NAD(+) + H2O


name: CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Bos taurus)


name: (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + O2 <=> (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E)-docosapentaenoate


name: 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) <=> 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)


name: ESD dimer hydrolyses S-FGSH to GSH (Homo sapiens)


name: PGH2 is degraded to 12S-HHT and MDA by TBXAS1 (Sus scrofa)


name: 2 a ubiquinol + O2(in) + 4 H(+)(in) => 2 a ubiquinone + 2 H2O(in) + 4 H(+)(out)


name: (2E)-octenoyl-[ACP] + NADH + H(+) => octanoyl-[ACP] + NAD(+)


name: OMA1 hydrolyses OPA1 (Rattus norvegicus)


name: 2 hydrogencarbonate(in) + chloride(out) = 2 hydrogencarbonate(out) + chloride(in)


name: Vamp2 associated secretory vesicle to plasma membrane transport (Bos taurus)


name: AFG3L2 binds mitochondrial matrix proteins (Drosophila melanogaster)


name: Exocytosis of azurophil granule lumen proteins (Drosophila melanogaster)


name: SOX10, POU3F1 and POU3F2 bind EGR2 gene (Homo sapiens)


name: apigenin + UDP-alpha-D-glucose <=> apigenin 7-O-beta-D-glucoside + UDP + H(+)


name: MITF-M dimer binds RAB27A gene (Homo sapiens)


name: PAOX:FAD oxidises NASPN to SPM (Homo sapiens)


name: 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ATP + H(+) <=> 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP


name: CCND1 recruits HDAC4 to RUNX3 (Drosophila melanogaster)


name: NAD(+)(in) + CoA(out) => NAD(+)(out) + CoA(in)


name: 4-chlorobenzoate + ATP + CoA <=> 4-chlorobenzoyl-CoA + AMP + diphosphate


name: Collagen type III degradation by MMP1,8,9,13 (Mus musculus)


name: dimethyl sulfide + AH2 <=> methane + methanethiol + A


name: SGC:DAG1:SSPN complex translocates to plasma membrane (Homo sapiens)


name: Phosphorylation of JAK2 (Rattus norvegicus)


name: Formation of a heteromeric BMP receptor complex (Danio rerio)


name: N-(13Z-docosenoyl)-sphinganine + CoA + H(+) => (13Z)-docosenoyl-CoA + sphinganine


name: activation of nucleoside diphosphate reductase activity


name: PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates (Rattus norvegicus)


name: SRD5A2 dehydrogenates TEST to DHTEST (Rattus norvegicus)


name: 7-O-methyldeacetylisoipecoside + S-adenosyl-L-methionine => 6,7-O,O-dimethyldeacetylisoipecoside + S-adenosyl-L-homocysteine + H(+)


name: SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Caenorhabditis elegans)


name: D-loop extension by DNA polymerases (Bos taurus)


name: EYA1-4 dephosphorylates tyrosine Y142 of H2AFX (Gallus gallus)


name: Unknown kinase phosphorylates CLEC1B dimer:PDPN (Bos taurus)


name: Follistatin (FST) binds Activin (Drosophila melanogaster)


name: L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine


name: Clusterin binds C5b-C7, C8, C9 (Homo sapiens)


name: Nephrin interacts with Podocin (Caenorhabditis elegans)


name: Fromation of the preholoimmunoproteasome (Plasmodium falciparum)


name: NEDD8-K699-CUL2:ELOB:ELOC:RBX1:KLHDC10 K48 polyubiquitinates alanine-tailed nascent peptide (Bos taurus)


name: Formation of DSIF complex  (Plasmodium falciparum)


name: CDC42 GDIs block activation of CDC42 (Drosophila melanogaster)


name: adenosine(57)/adenosine(58) in tRNA + 2 S-adenosyl-L-methionine => N(1)-methyladenosine(57)/N(1)-methyladenosine(58) in tRNA + 2 S-adenosyl-L-homocysteine + 2 H(+)


name: (2E,6E)-farnesyl diphosphate = (E)-2-epi-beta-caryophyllene + diphosphate


name: SALMs 1-3 bind to PSD-95 family members (Drosophila melanogaster)


name: N-tetradecanoylsphing-4-enine + H2O => tetradecanoate + sphing-4-enine


name: chloroethene + AH2 = ethene + chloride + A + H(+)


name: miR-92b binds 3'UTR of NLK mRNA (Homo sapiens)


name: N-acetyl-L-aspartate(in) + ATP + H2O = N-acetyl-L-aspartate(out) + ADP + phosphate + H(+)


name: a primary amine + 3'-phosphoadenylyl sulfate = a sulfamate + adenosine 3',5'-bisphosphate + 2 H(+)


name: Activated FGFR2 binds SHC1 (Gallus gallus)


name: NANS converts ManNAc-6-P to Neu5Ac-9-P (Canis familiaris)


name: melibiose(in) + Na(+)(in) = melibiose(out) + Na(+)(out)


name: gamma-L-glutamyl-L-glutamyl-[protein] + ADP + phosphate + H(+) => L-glutamyl-[protein] + L-glutamate + ATP


name: (2E,6E)-farnesol + NADP(+) <=> (2E,6E)-farnesal + NADPH + H(+)


name: Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Danio rerio)


name: AKRs reduce RBP2:atRAL to RBP2:atROL (Xenopus tropicalis)


name: TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8 (Homo sapiens)


name: Deubiquitinated PTEN translocates to the cytosol (Caenorhabditis elegans)


name: hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances


name: SUMOylation of NFKBIA with SUMO1 (Rattus norvegicus)


name: isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Bos taurus)


name: heptanoate + NADH + 2 H(+) => heptanal + NAD(+) + H2O


name: SBF1 binds MTMR2 (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate


name: B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker (Bos taurus)


name: D-threo-isocitrate => cis-aconitate + H2O


name: Monoubiquitinated PTEN translocates to the nucleus (Dictyostelium discoideum)


name: SERPINC1 binds SERPINC1 activators (Sus scrofa)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + H2O


name: Cellular Structure Molecule Interactions


name: PLK1 phosphorylates BORA (Xenopus tropicalis)


name: Phosphorylated AMPK binds AMP (Sus scrofa)


name: decan-1-ol + hexadecanoyl-CoA <=> decanyl hexadecanoate + CoA


name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Sus scrofa)


name: SB-203207 + (3R)-3-methyl-L-phenylalanyl-[peptidyl carrier-protein] = SB-203208 + holo-[peptidyl-carrier protein]


name: prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) (Canis familiaris)


name: glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] (Saccharomyces cerevisiae)


name: D-cellobiose + A => D-cellobiono-1,5-lactone + AH2


name: Association of procollagen type X (Sus scrofa)


name: Defective DPM2 does not transfer mannose to DOLP to form DOLPman (Homo sapiens)


name: 5-oxo-L-proline + ATP + 2 H2O = L-glutamate + ADP + phosphate + H(+)


name: Melanin-concentrating hormone receptors bind MCH (Canis familiaris)


name: SUMOylation of HDAC2 with SUMO1 (Gallus gallus)


name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Gallus gallus)


name: FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)


name: FLT3LG dimer:FLT3 binds FLT3 (Bos taurus)


name: a (7Z,10Z,13Z,16Z)-docosatetraenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => a (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: a (7S)-7-hydroxy-C2-C8-saturated long-chain fatty acyl-[ACP] + reduced [flavodoxin] + O2 <=> a (7R,8R)-7,8-dihydroxy-C2-C8-saturated long-chain fatty acyl-[ACP] + oxidized [flavodoxin] + H2O + H(+)


name: TRIM25 binds monoUb:164-PCNA (Danio rerio)


name: 3-oxo-(11Z)-eicosenoyl-CoA + NADPH + H(+) = (3R)-hydroxy-(11Z)-eicosenoyl-CoA + NADP(+)


name: inositol monophosphate 1-phosphatase activity


name: ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix (Mus musculus)


name: Formation of the closed pre-initiation complex (Canis familiaris)


name: Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Rattus norvegicus)


name: MAP2K2 phosphorylates MAPK1 (Bos taurus)


name: Activated PTK6 binds CDKN1B (Rattus norvegicus)


name: Diiodinated tyrosine can be deiodinated (Drosophila melanogaster)


name: acetylpyruvate + H2O <=> acetate + pyruvate + H(+)


name: 4alpha-carboxyzymosterol + NAD(+) => zymosterone + CO2 + NADH


name: phosphoenolpyruvate + AMP + phosphate + 2 H(+) => pyruvate + ATP + H2O


name: positive regulation of cytochrome oxidase activity


name: (3R)-hydroxy-(21Z,24Z,27Z,30Z)-hexatriacontatetraenoyl-CoA = (2E,21Z,24Z,27Z,30Z)-hexatriacontapentaenoyl-CoA + H2O


name: F-actin capping protein binds to the barbed end of elongating F-actin (Homo sapiens)


name: (2R)-3-phosphoglycerate + GTP + H(+) => 3-[(R)-glyceryl]-diphospho-5'-guanosine + diphosphate


name: 2-oxopent-4-enoate + CO2 => (3E)-2-oxohex-3-enedioate + H(+)


name: positive regulation of interleukin-4-mediated signaling pathway


name: HS2ST1 trimer sulfates IdoA at C2 in heparan sulfate (Xenopus tropicalis)


name: an omega-hydroxy fatty acid + reduced [NADPH--hemoprotein reductase] + O2 => an omega-oxo fatty acid + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: Activated FGFR4 phosphorylates FRS2 (Mus musculus)


name: SHPK phosphorylates Sedo to Sedo7P (Xenopus tropicalis)


name: pyridoxal + ATP = pyridoxal 5'-phosphate + ADP + H(+)


name: 3-oxo-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + NADPH + H(+) <=> (3R)-hydroxy-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + NADP(+)


name: C4b binds to target cell surface (Gallus gallus)


name: HNF6-dependent synthesis of ONECUT3 protein during early pancreas specification (Homo sapiens)


name: B3GALT6 transfers Gal to the tetrasaccharide linker (Bos taurus)


name: RAC3 translocates to the endoplasmic reticulum membrane (Drosophila melanogaster)


name: NEMF binds 60S ribosomal subunit:peptidyl-tRNA with nascent peptide (Rattus norvegicus)


name: aminotriazole transmembrane transporter activity


name: CK1 phosphorylates p-GLI3 (Gallus gallus)


name: RHAG transports CO2 from cytosol to extracellular region (Gallus gallus)


name: n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine + H2O => [hyaluronan](n)


name: (+)-copalyl diphosphate + H2O <=> phyllocladan-16alpha-ol + diphosphate


name: dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Rattus norvegicus)


name: a 3'-hydroxyflavone + S-adenosyl-L-methionine => a 3'-methoxyflavone + S-adenosyl-L-homocysteine + H(+)


name: TRIBOA beta-D-glucoside + succinate + CO2 => DIBOA beta-D-glucoside + 2-oxoglutarate + O2


name: N-tetracosanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) <=> N-tetracosanoylsphinganine-(1D-myo-inositol) + a 1,2-diacyl-sn-glycerol


name: (E)-caffeoyl-AMP + diphosphate => (E)-caffeate + ATP + H(+)


name: factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer (Gallus gallus)


name: TNFSF11 binds TNFRSF11A, B (Xenopus tropicalis)


name: Dissociation of Phospho-Nlp from the centrosome (Xenopus tropicalis)


name: Addition of a second mannose to the N-glycan precursor by ALG2 (Mus musculus)


name: L-alanyl-tRNA(Pro) + H2O <=> tRNA(Pro) + L-alanine + H(+)


name: 1-acyl LPA is acylated to PA by AGPAT (LPAAT) (Mus musculus)


name: methanethiol + formaldehyde + NAD(+) + H2O => dimethyl sulfide + NADH + O2 + H(+)


name: asc-C9-CoA + O2 <=> asc-DeltaC9-CoA + H2O2


name: Defective SGSH does not hydrolyse Heparan sulfate chain(7) (Homo sapiens)


name: acrylate + NADH + 2 H(+) => acrolein + NAD(+) + H2O


name: alcohol dehydrogenase (cytochrome c) activity


name: N-glycolylneuraminic acid (Neu5Gc) cytidylyltransferase activity


name: TFIIH binds GG-NER site to form a verification complex (Gallus gallus)


name: FOXO3 translocates from the mitochondrial matrix to the nucleus (Xenopus tropicalis)


name: isoguanine + H2O + H(+) = xanthine + NH4(+)


name: 7alpha,12alpha-dihydroxy-3-oxochol-24-oyl-CoA + NAD(+) => 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H(+)


name: dimethyl sulfide + menaquinone-8 + H2O => dimethyl sulfoxide + menaquinol-8


name: TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK (Xenopus tropicalis)


name: PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Gallus gallus)


name: ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Plasmodium falciparum)


name: Phosphorylation of YAP by LATS1 (Sus scrofa)


name: (2E)-decenoyl-CoA + H2O = 3-hydroxydecanoyl-CoA


name: N-terminal glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-methionine <=> N-terminal N-methyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-homocysteine + H(+)


name: taurodeoxycholate + 3'-phosphoadenylyl sulfate => 3alpha-sulfotaurodeoxycholate + adenosine 3',5'-bisphosphate + H(+)


name: PNLIP:CLPS hydrolyses RPALM to atROL and PALM (Mus musculus)


name: alpha-D-glucose + D-glucose => D-maltose + H2O


name: 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = 2-octadecanoyl-sn-glycero-3-phosphocholine + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H(+)


name: PRKN ubiquitinates MOM substrates (Saccharomyces cerevisiae)


name: N(tele)-methyl-trans-urocanate + H2O => 3-methylimidazol-4-one-5-propanoate


name: (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + NADP(+) + 2 H2O <=> (4S)-4-hydroxy-L-glutamate + NADPH + H(+)


name: Interaction of integrin alpha9beta1 with Tenascin-C (Caenorhabditis elegans)


name: deacetoxyvindoline + S-adenosyl-L-homocysteine + H(+) => (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine


name: IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation (Homo sapiens)


name: UDP-N-acetyl-alpha-D-galactosamine + diphosphate => N-acetyl-alpha-D-galactosamine 1-phosphate + UTP + H(+)


name: (11Z,14Z)-eicosadienoate + NH4(+) => (11Z,14Z)-eicosadienamide + H2O


name: Endocytosis of cya:lef:(pagA(197-794):ANTXR1 oligomer) (plasma membrane to endosome membrane) (Homo sapiens)


name: 28S subunit:MTIF3 binds MTIF2:GTP, mRNA, and formylMet-tRNA (Homo sapiens)


name: Proteolytic PAK-2p34 fragment translocates to the nucleus (Homo sapiens)


name: (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: HGFAC cleaves pro-HGF to form HGF dimer (Homo sapiens)


name: Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane (Gallus gallus)


name: In the absence of ARM, GRO binds to PAN and inhibits transcription (Drosophila melanogaster)


name: PSMD11 binds PSMD7:PSMD12:PSMD13:PSMD14 (Homo sapiens)


name: (3Z)-2-oxo-4-carboxy-3-hexenedioate + H2O <=> (2S)-2-hydroxy-4-oxobutane-1,2,4-tricarboxylate


name: ERBB2 T862A does not bind sapitinib (Homo sapiens)


name: Plasma membrane resorption (Rattus norvegicus)


name: 1-acyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphoethanolamine + CoA => (9Z)-hexadecenoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: Nephrin interacts with Podocin (Danio rerio)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) => a 1-acyl-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)


name: PXLP-K333-GADL1 decarboxylates CSA to HTAU (Canis familiaris)


name: Soluble PROCR binds PRTN3:CD177 (Sus scrofa)


name: HDHD1:Mg2+ dephosphorylates PURIDP (Homo sapiens)


name: a medium-chain 3-oxoacyl-[ACP] + dihydroxyacetone phosphate = a (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate + holo-[ACP] + H2O


name: L-prolyl-tRNA(Pro) + L-arginyl-tRNA(Arg) => cyclo(L-arginyl-L-prolyl) + tRNA(Pro) + tRNA(Arg) + 2 H(+)


name: (-)-vincadifformine + reduced [NADPH--hemoprotein reductase] + O2 = (-)-minovincinine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: a beta-D-glucosylceramide + H2O <=> an N-acyl-sphingoid base + D-glucose


name: CGRP receptor can bind calcitonin gene-related peptides (Danio rerio)


name: Association of procollagen type XII (Xenopus tropicalis)


name: (S)-lactate + L-lysyl-[protein] => N(6)-[(S)-lactoyl]-L-lysyl-[protein] + H2O


name: down regulation of non-chaperonin molecular chaperone ATPase activity


name: (25R)-cholest-5-en-3beta,7alpha,26-triol + NAD(+) <=> (25R)-7alpha,26-dihydroxycholest-4-en-3-one + NADH + H(+)


name: CYP2C19 5-hydroxylates omeprazole (Homo sapiens)


name: KLK5 cleaves and activates CELA2 (Sus scrofa)


name: Beclin-1 complex phosphorylates PtdIns (Gallus gallus)


name: cob(I)alamin-[alkylcobalamin reductase] + an S-substituted glutathione + H(+) => apo-[alkylcobalamin reductase] + an R-cob(III)alamin + glutathione


name: D-leucine + O2 + H2O => 4-methyl-2-oxopentanoate + H2O2 + NH4(+)


name: [DsbA protein]-disulfide + a quinol => [DsbA protein]-dithiol + a quinone


name: ent-kaur-16-en-19-al + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + H(+) => ent-kaur-16-en-19-oate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: N-acetyl-L-aspartyl-L-glutamate(out) + ADP + phosphate + H(+) => N-acetyl-L-aspartyl-L-glutamate(in) + ATP + H2O


name: Ca2+ influx through voltage gated Ca2+ channels (Canis familiaris)


name: D-mannitol 1-phosphate + NADP(+) = D-mannose 6-phosphate + NADPH + H(+)


name: ACER3 hydrolyzes phytoceramide (Dictyostelium discoideum)


name: maltose + H2O => 2 D-glucose (maltase-glucoamylase) (Gallus gallus)


name: Syndecans 2, (4) bind TGFB1 (Sus scrofa)


name: CBL ubiquitinates FRS2 and FGFR2 (Drosophila melanogaster)


name: 2 D-maltotetraose = alpha-isomaltosyl-(1->4)-D-maltotriose + D-maltotriose


name: PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Homo sapiens)


name: phytol + a fatty acyl-CoA = a fatty acid phytyl ester + CoA


name: (6aS,11aS)-4-dimethylallyl-3,6a,9-trihydroxypterocarpan + reduced [NADPH--hemoprotein reductase] + O2 => glyceollin I + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 (Mus musculus)


name: N-(7'-carboxy-7'-demethylgeranyl)-L-glutamate + 2-oxoglutarate + O2 => isodomoate A + succinate + CO2 + H2O


name: 4-hydroxy-6-(2-oxoundec-10-en-1-yl)pyran-2-one + 3 CO2 + 4 CoA => 9-decenoyl-CoA + 3 malonyl-CoA + 3 H(+)


name: Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) (Danio rerio)


name: TYRP1 oxidises DHICA to IQCA (Danio rerio)


name: 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-D-myo-inositol + CoA


name: (S)-linalool + diphosphate => (2E)-geranyl diphosphate + H2O


name: a 3beta-hydroxy-4alpha-methylsteroid-4beta-carboxylate + NADP(+) => a 4alpha-methyl-3-oxosteroid + CO2 + NADPH


name: The APOE gene transcription is stimulated by the complex of TFAP2A homodimer and DEK (Homo sapiens)


name: PRICKLE1 is degraded by the proteasome (Danio rerio)


name: a menaquinol + NAD(+) => a menaquinone + NADH + H(+)


name: 4-nitrocyclohexa-2,5-dien-1-one + arsenite + A + H(+) => nitarsone (III) + AH2 + O2


name: an NDP-alpha-D-glucose + D-glucose <=> alpha,alpha-trehalose + a ribonucleoside 5'-diphosphate + H(+)


name: choloyl-CoA + glycine => glycocholate + CoA + H(+)


name: positive regulation of manganese superoxide oxidoreductase


name: Interaction of PECAM-1 and SHIP (Gallus gallus)


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + 6 Fe(II)-[cytochrome b5] + 3 O2 + 5 H(+) = 4beta-methylzymosterol-4alpha-carboxylate + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: CYP2E1 monooxygenates APAP to NAPQI (Drosophila melanogaster)


name: (R)-lavandulyl diphosphate + H2O = (R)-lavandulol + diphosphate


name: SIRT4 cleaves lipoyl from DLAT (Sus scrofa)


name: STAMBPL1 is a deubiquitinase (Bos taurus)


name: CLPXP degrades mitochondrial matrix proteins (Mus musculus)


name: ALPI dimer hydrolyses phosphate monoesters (Xenopus tropicalis)


name: L-idonate + NADP(+) => 5-dehydro-D-gluconate + NADPH + H(+)


name: IDUA hydrolyses the unsulfated alpha-L-iduronosidic link in DS (Homo sapiens)


name: CYP3A4 oxidizes PREDN,PREDL (Mus musculus)


name: coenzyme F420-1:gamma-L-glutamate ligase activity


name: p62 links damaged mitochondria to LC3 (Caenorhabditis elegans)


name: TNF-α:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 (Sus scrofa)


name: (3R)-hydroxy-(14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA => (2E,14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontaheptaenoyl-CoA + H2O


name: a 3-O-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + CMP-N-acetyl-beta-neuraminate => a 3-O-[N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + CMP + H(+)


name: 8-oxo-dAMP + diphosphate + H(+) => 8-oxo-dATP + H2O


name: 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol <=> 1,2-ditetradecanoyl-sn-glycerol + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: FeHM dissociates from MetHb (Homo sapiens)


name: LIAS synthesizes lipoyl-GCSH (Canis familiaris)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Dictyostelium discoideum)


name: Furin cleaves pro-factor VII to factor VII (Canis familiaris)


name: N-(9Z-octadecenoyl)-L-tryptophan + H2O <=> L-tryptophan + (9Z)-octadecenoate


name: (R)-pantothenate(in) + 2 Na(+)(in) => (R)-pantothenate(out) + 2 Na(+)(out)


name: Synthesis of PIP3 from PIP2 by PI3K (Homo sapiens)


name: Competitive inhibition of translation initiation by ISGylated 4EHP (Xenopus tropicalis)


name: an (E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amine + H2O2 + H(+) => an N-(1-deoxy-beta-D-fructopyranos-1-yl)amine + O2


name: glycoursodeoxycholate + NADP(+) = 7-oxoglycolithocholate + NADPH + H(+)


name: alpha,alpha'-trehalose 6,6'-bismycolate + alpha,alpha-trehalose => 2 alpha,alpha'-trehalose 6-mycolate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: EPCAM binds itself to form homotypic cell adhesion (Homo sapiens)


name: SHPK phosphorylates Sedo to Sedo7P (Bos taurus)


name: 3-dehydro-4-O-phospho-L-erythronate + H(+) = dihydroxyacetone phosphate + CO2


name: spermidine(out) + H(+)(in) => spermidine(in) + H(+)(out)


name: Mg(2+)(out) + ATP + H2O = Mg(2+)(in) + ADP + phosphate + H(+)


name: ADP + phosphate + NADPH + H(+) => (6S)-NADPHX + ATP


name: GLI2,3 are degraded by the proteasome (Mus musculus)


name: H139Hfs13* PPM1K does not dephosphorylate BCKDH (Homo sapiens)


name: Methylthio-ribose-P => Methylthio-ribulose-P (Bos taurus)


name: protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity


name: (S,S)-drim-8-en-11-yl phosphate + H2O <=> (S,S)-drim-8-en-11-ol + phosphate


name: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Homo sapiens)


name: OAS1 produces oligoadenylates (Homo sapiens)


name: Activation of proMMP11 by FURIN (Gallus gallus)


name: 1-propanol + butanoyl-CoA = propyl butanoate + CoA


name: TRPV1 binds TRPV1 agonists (Xenopus tropicalis)


name: regulation of apoptotic DNA fragmentation


name: ABC7, mABC1 and mABC2 mediate heme transport (Caenorhabditis elegans)


name: a reduced flavin + NAD(+) <=> an oxidized flavin + NADH + 2 H(+)


name: 3-methyl-2-aminobutane + NADP(+) + H2O = 3-methylbutan-2-one + NH4(+) + NADPH + H(+)


name: kanamycin A + UDP + H(+) => 2'-deamino-2'-hydroxyneamine + UDP-alpha-D-kanosamine


name: CCNG2 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) (Homo sapiens)


name: PTK6 phosphorylates KHDRBS2 (Bos taurus)


name: 2-(prostaglandin G2)-sn-glycero-3-phosphocholine + AH2 => 2-(prostaglandin H2)-sn-glycero-3-phosphocholine + A + H2O


name: D-allose 6-phosphate + ADP + H(+) => D-allose + ATP


name: LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA (Drosophila melanogaster)


name: PROT mediates L-proline uptake (Xenopus tropicalis)


name: (9Z,12Z)-octadecadienoyl-CoA + a 1-acyl-sn-glycero-3-phosphocholine = 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA


name: Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Rattus norvegicus)


name: phenylalanine + pyruvate => keto-phenylpyruvate + alanine (Dictyostelium discoideum)


name: leukotriene B4 + reduced [NADPH--hemoprotein reductase] + O2 = 18-hydroxy-leukotriene B4 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: dalnigrein + beta-D-apiofuranosyl-(1->6)-D-glucopyranose + H(+) => dalnigrein beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside + H2O


name: G alpha (q):RGS dissociates to inactive G alpha (q) (Homo sapiens)


name: RRAGA,B exchanges GDP for GTP (Dictyostelium discoideum)


name: Activated P2Y purinoceptor 12 binds G-protein Gi (Homo sapiens)


name: (E)-alk-1-en-1-SO-peroxol = (Z)-alkanethial oxide


name: TST transfers sulfur from S2O3(2-) to HCN to form HSCN (Rattus norvegicus)


name: Retromer recycles WLS to the Golgi (Schizosaccharomyces pombe)


name: Hh-Npp binds CDON and PTCH (Gallus gallus)


name: N-decanoyl-1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O = N-decanoyl ethanolamine + 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H(+)


name: 4-hydroxy-3-(all-trans-octaprenyl)benzoate + H(+) = 2-all-trans-octaprenylphenol + CO2


name: malonate + CoA + H(+) => malonyl-CoA + H2O


name: (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + UDP + H(+) => (2R)-3-phosphoglycerate + UDP-alpha-D-glucose


name: Inactive G alpha (i) reassociates with G beta:gamma (Canis familiaris)


name: (2S)-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]pentanedioate + H2O + H(+) => 2-dehydro-D-glucose + L-glutamate


name: 3-(4-hydroxyphenyl)pyruvate + H2O2 + NH4(+) => L-tyrosine + O2 + H2O


name: MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Mus musculus)


name: L-lysine + 2-oxoglutarate = (S)-2-amino-6-oxohexanoate + L-glutamate


name: (3R,6R)-3-hydroxy-10'-apo-alpha-carotenal + O2 = (3R,6R)-hydroxy-alpha-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial


name: BAP1 binds BRCA1:BARD1 heterodimer (Homo sapiens)


name: beta-D-Delta(4)-GlcA-(1->4)-beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc + H2O = beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc + 5-dehydro-4-deoxy-D-glucuronate


name: protein C-linked glycosylation via tryptophan


name: a ganglioside GP1calpha (d18:1(4E)) + CMP + H(+) => a ganglioside GQ1c (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: 17-hydroperoxy-(7Z,10Z,13Z,15E,19Z)-docosapentaenoate => (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2


name: a globoside IV3GalNAc-Gb4Cer + H2O <=> N-acetyl-alpha-D-galactosamine + a globoside Gb4Cer


name: 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate + CTP = CMP-beta-3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate + diphosphate


name: peroxisome membrane class-2 targeting sequence binding


name: urea(in) + ADP + phosphate + H(+) => urea(out) + ATP + H2O


name: NADK2 dimer phosphorylates NAD+ to NADP+ (Mus musculus)


name: 4-chlorophenylacetate + NADH + O2 => 3,4-dihydroxyphenylacetate + chloride + NAD(+)


name: prostaglandin I2 + reduced [NADPH--hemoprotein reductase] + O2 => 19-hydroxy-prostaglandin I2 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: RAC1 binds effectors at the plasma membrane (Gallus gallus)


name: L-sepiapterin + H2O => 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + H(+)


name: hexadecanal dehydrogenase (acylating) activity


name: glycyl-L-leucine(out) + 2 H(+)(out) = glycyl-L-leucine(in) + 2 H(+)(in)


name: Recognition of AAUAAA sequence by CPSF (Caenorhabditis elegans)


name: 11alpha-hydroxy-beta-amyrin + reduced [NADPH--hemoprotein reductase] + O2 <=> 11-oxo-beta-amyrin + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: FMN-N(5)-peroxide + uracil = (Z)-3-ureidoacrylate + FMN-N(5)-oxide + 2 H(+)


name: tissue factor (TF) + factor VII (F7) -> TF:F7 complex (Canis familiaris)


name: broad specificity oxidative DNA demethylase activity


name: a (2R)-2-hydroxycarboxylate + a quinone = a 2-oxocarboxylate + a quinol


name: Activated FGFR3 point, translocation and fusion mutants:p-FRS2 binds GRB2-SOS1 (Homo sapiens)


name: cortisone + NADPH + H(+) = cortisol + NADP(+)


name: diacylglycerol-dependent serine/threonine kinase activity


name: p-PKR dimer phosphorylates TP53 tetramer (Rattus norvegicus)


name: 18-hydroxy-9alpha,11alpha-methylene thromboxane A2 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => 9alpha,11alpha-methylene thromboxane A2 + reduced [NADPH--hemoprotein reductase] + O2


name: Degradation of multiubiquitinated Securin (Mus musculus)


name: cyclohexylamine + O2 + H2O = cyclohexanone + H2O2 + NH4(+)


name: HOXD4 gene is transcribed (Homo sapiens)


name: N(6)-acetyl-L-lysine + 2-oxoglutarate = 6-acetamido-2-oxohexanoate + L-glutamate


name: N-hexanoyl-sphing-4-enine-1-phosphocholine => N-(hexanoyl)-sphing-4-enine-1,3-cyclic phosphate + choline


name: dihydroxyacetone phosphate + H2O => dihydroxyacetone + phosphate


name: thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ (Caenorhabditis elegans)


name: hydroxymethylglutaryl coenzyme A-condensing enzyme


name: taurochenodeoxycholate + 3'-phosphoadenylyl sulfate = taurochenodeoxycholate 7-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: DVL1 is ubiquitinated by HECW1 (Rattus norvegicus)


name: LXA4 is oxidised to 15k-LXA4 by HPGD (Rattus norvegicus)


name: ethylene anabolism during jasmonic acid and ethylene-dependent systemic resistance


name: Association of Nek2A with MCC:APC/C (Rattus norvegicus)


name: Kinetochore capture of astral microtubules (Canis familiaris)


name: PI is exchanged with PC by PITPNB (Plasmodium falciparum)


name: (2E,6E)-farnesyl diphosphate + H2O <=> kunzeaol + diphosphate


name: Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Drosophila melanogaster)


name: SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Sus scrofa)


name: oleanolate + reduced [NADPH--hemoprotein reductase] + O2 => cochalate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 7,9,10-trihydroxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + 7 CO2 + 8 CoA + 2 H2O => 7 malonyl-CoA + acetyl-CoA + 7 H(+)


name: WDR83:LAMTOR2:LAMTOR3 binds MAPK components (Canis familiaris)


name: NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Sus scrofa)


name: AKR1C3 reduces atRAL to atROL (Xenopus tropicalis)


name: 6 malonyl-CoA + acetyl-CoA + 4 H(+) => 2-(2,4-dihydroxy-6-oxidobenzoyl)-5-hydroxy-3-methylbenzenolate + 6 CO2 + 7 CoA + H2O


name: KCTD1 binds TFAP2 homo- and heterodimers (Mus musculus)


name: oxytetracycline + NADPH + O2 + H(+) => 11a-hydroxy-oxytetracycline + NADP(+) + H2O


name: 2,5-dicarboxyfuran + 3 H2O2 + 2 H(+) => 5-hydroxymethylfurfural + 3 O2 + 2 H2O


name: cytidine(38) in tRNA + S-adenosyl-L-methionine <=> 5-methylcytidine(38) in tRNA + S-adenosyl-L-homocysteine + H(+)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 (Gallus gallus)


name: Association of Acrosin Heavy and Light Chain (Xenopus tropicalis)


name: CSF3R gene expression is enhanced by SPI1 (PU.1), CEBPA, and DEK (Homo sapiens)


name: UXS1 tetramer decarboxylates UDP-glucuronate to UDP-xylose (Drosophila melanogaster)


name: CITED2 gene expression is stimulated by FOXO1,FOXO3 (Homo sapiens)


name: mogroside III-A1 + UDP-alpha-D-glucose = siamenoside I + UDP + H(+)


name: Autophosphorylation of PAK (Mus musculus)


name: MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met (Homo sapiens)


name: ergothioneine(in) + ADP + phosphate + H(+) => ergothioneine(out) + ATP + H2O


name: 3,6-dichloro-2-methoxybenzoate + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 3,6-dichlorosalicylate + formaldehyde + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: Gt-GTP dissociates to GNAT1-GTP and GNB1:GNGT1 (Xenopus tropicalis)


name: IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 (Gallus gallus)


name: ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 (Dictyostelium discoideum)


name: PLK1 phosphorylates NUDC (Gallus gallus)


name: tBID binds to inactive BAK protein (Canis familiaris)


name: 2 vanillin => 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O2


name: Caspase-mediated cleavage of Desmoglein 3 (Xenopus tropicalis)


name: PDCL promotes formation of G-beta:G-gamma heterodimers (Drosophila melanogaster)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 (Saccharomyces cerevisiae)


name: The IFT-A complex recruits TULP3 (Homo sapiens)


name: 3-O-[beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-2-O-P-Xyl]-L-seryl-[protein] + H2O = 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + phosphate


name: an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1-acyl-sn-glycero-3-phosphocholine + H(+) => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: JMJD6 demethylates MeR3-histone H3 (Bos taurus)


name: PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Dictyostelium discoideum)


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-beta-D-GlcNAc derivative + GDP + H(+) => an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-D-GlcNAc derivative + GDP-beta-L-fucose


name: rebaudioside B + UDP + H(+) => steviolbioside + UDP-alpha-D-glucose


name: [(2->6)-alpha-D-glucosyl-(1->4)-N-acetyl-alpha-D-neuraminosyl](n) + n acetyl-CoA = [(2->6)-alpha-D-glucosyl-(1->4)-N,O(9)-diacetyl-alpha-D-neuraminosyl](n) + n CoA


name: ALOX15 oxidises DHA to 17(S)-Hp-DHA (Homo sapiens)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate = (-)-astellatene + diphosphate


name: fusidate(in) + H(+)(out) = fusidate(out) + H(+)(in)


name: PC is hydrolyzed to PA and choline by PLD1/2 (Rattus norvegicus)


name: MADCAM1-1 binds Integrin alpha4beta7 (Homo sapiens)


name: RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Homo sapiens)


name: Direct Host Cell Membrane Membrane Fusion and Release of SARS-CoV-2 Nucleocapsid (Homo sapiens)


name: PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Dictyostelium discoideum)


name: NEIL1 translocates to the nucleus (Danio rerio)


name: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + H(+) => 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + CO2


name: Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Danio rerio)


name: CYP2A13 oxidises AFM1 to AFM1E (Caenorhabditis elegans)


name: DIMBOA + UDP-alpha-D-glucose = DIMBOA beta-D-glucoside + UDP + H(+)


name: (2S)-versicolorone + NADP(+) => 1'-hydroxyversicolorone + NADPH + H(+)


name: p-Y694-STAT5A, p-STAT5B dimerizes (Sus scrofa)


name: L-fucono-1,5-lactone + H2O = L-fuconate + H(+)


name: a hydroperoxide + 2 glutathione <=> an alcohol + glutathione disulfide + H2O


name: androst-5-ene-3,17-dione + NADH + H(+) => 3beta-hydroxyandrost-5-en-17-one + NAD(+)


name: arsenate reductase (glutaredoxin) activity


name: ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Xenopus tropicalis)


name: a long-chain fatty acyl ethyl ester + H2O => a long-chain fatty acid + ethanol + H(+)


name: membrane protein intracellular domain proteolysis


name: IL1R1 binds IL1R1 inhibitors (Bos taurus)


name: Acitretin binds to RAR:RXR (Danio rerio)


name: D-fructose 6-phosphate + H2O => D-fructose + phosphate


name: TRAF6 binding leads to IRAK1:TRAF6 release (Mus musculus)


name: HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Canis familiaris)


name: 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA + H2O => 3-hydroxy-6-carboxyhexanoyl-CoA + H(+)


name: D-maltotetraose + H2O = D-maltotriose + alpha-D-glucose


name: N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP (Xenopus tropicalis)


name: PON1,3 hydrolyse ATVL to ATV (Sus scrofa)


name: N(4)-(ADP-D-ribosyl)-L-asparaginyl-[protein] + H2O = L-asparaginyl-[protein] + ADP-D-ribose


name: a 1-acyl-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA => a 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA


name: L-alanyl-L-aspartate + H2O => L-aspartate + L-alanine


name: 2 thiosulfate(out) + (S)-malate(in) => 2 thiosulfate(in) + (S)-malate(out)


name: 2-aminopentan-1-ol + NAD(+) + H2O <=> 1-hydroxypentan-2-one + NH4(+) + NADH + H(+)


name: a 2'-deoxyuridine in double-stranded DNA + NH4(+) => a 2'-deoxycytidine in double-stranded DNA + H2O + H(+)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR4 (Homo sapiens)


name: tetracosanoate + sphinganine => N-tetracosanoylsphinganine + H2O


name: RDH5 oxidises 11cROL to 11cRAL (Bos taurus)


name: TFAM binds to mitochondrial promoters (Xenopus tropicalis)


name: 2 a quinone + NADH + H(+) <=> 2 a 1,4-benzosemiquinone + NAD(+)


name: ethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoate => N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + H2O


name: PLC beta-mediated PIP2 hydrolysis (Xenopus tropicalis)


name: linear 1,3-beta-D-glucan synthase activity