name: BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins (Rattus norvegicus)


name: Fe(II)-heme i + A + H2O => Fe(II)-hydroxyheme i + AH2


name: PXLP-K405-GAD1 decarboxylates L-Glu to form GABA (Rattus norvegicus)


name: SLC2A1,3 transports DeHA from extracellular region to cytosol (Caenorhabditis elegans)


name: Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Dictyostelium discoideum)


name: UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose + CoA + H(+) => UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + acetyl-CoA


name: HP1 alpha binds Histone H3K9(me)3 (Gallus gallus)


name: Phosphorylation of Smooth Muscle Myosin Light Chains (Gallus gallus)


name: hancockiamide G + acetyl-CoA <=> hancockiamide C + CoA + H(+)


name: N(omega)-(N-acetyl-beta-D-glucosaminyl)-L-arginyl-[protein] + UDP + H(+) => L-arginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: Translocation of PDK1 to Plasma membrane (Dictyostelium discoideum)


name: p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 (Drosophila melanogaster)


name: TLE tetramers bind TCF/LEF at WNT promoters (Mus musculus)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 <=> (12S)-hydroperoxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate


name: lipid-linked peptidoglycan transporter activity


name: AKR1C1 hydrogenates PREDN,PREDL (Mus musculus)


name: 2-acyl LPC is acylated to PC by LPCAT (Saccharomyces cerevisiae)


name: Addition of Nucleotides 5 through 9 on the growing Transcript (Homo sapiens)


name: AK4 phosphorylates (d)NMPs to (d)NDPs (Homo sapiens)


name: beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 (Schizosaccharomyces pombe)


name: (2E,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + NADPH + H(+) => (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + NADP(+)


name: PI is hydrolyzed to 1-acyl LPI by PLA2[15] (Danio rerio)


name: 2-chloroethanol cytochrome-c oxidoreductase activity


name: 3,3',5-triiodo-L-thyronine + iodide + A + H(+) => L-thyroxine + AH2


name: SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids (Sus scrofa)


name: Defective B3GALTL does not transfer glucose to O-fucosyl-proteins (Homo sapiens)


name: an N-acylneuraminate 9-phosphate + H2O => an N-acylneuraminate + phosphate


name: L-alpha-aminoacyl-tRNA + acetyl-CoA => N-acetyl-L-alpha-aminoacyl-tRNA + CoA + H(+)


name: butyl sulfate + 2-oxoglutarate + O2 <=> butanal + sulfate + succinate + CO2 + H(+)


name: Activation of Ca-permeable Kainate receptors (Caenorhabditis elegans)


name: Hydrolysis of ATP and release of folded actin from CCT/TriC (Homo sapiens)


name: IL4I1:FAD oxidises L-Phe to kPPV (Dictyostelium discoideum)


name: acetone + hydrogencarbonate + 2 ATP + 3 H2O => acetoacetate + 2 AMP + 4 phosphate + 4 H(+)


name: N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine (Canis familiaris)


name: alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity


name: VEGF induces CDC42 activation by unknown mechanism (Homo sapiens)


name: IDH2 dimer decarboxylates isocitrate (Rattus norvegicus)


name: allantoate + 2 H2O + 2 H(+) => (S)-ureidoglycolate + 2 NH4(+) + CO2


name: D-cellobiose(out) + N(pros)-phospho-L-histidyl-[protein] <=> 6-phospho-beta-D-glucosyl-(1->4)-D-glucose(in) + L-histidyl-[protein]


name: THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Canis familiaris)


name: inosine(in) + H(+)(in) = inosine(out) + H(+)(out)


name: GMPS dimer transforms 6TXMP to 6TGMP (Plasmodium falciparum)


name: 3-hydroxydecanoyl-CoA => (2E)-decenoyl-CoA + H2O


name: high-affinity basic amino acid transmembrane transporter activity


name: L-histidine(out) + chloride(out) + 2 Na(+)(out) <=> L-histidine(in) + chloride(in) + 2 Na(+)(in)


name: holo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] + AMP + diphosphate + H(+) => apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] + biotin + ATP


name: p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane (Plasmodium falciparum)


name: a ganglioside GT1aalpha (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GQ1balpha (d18:1(4E)) + CMP + H(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA <=> (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate


name: Phosphorylated STAT92E dimer is dephosphorylated by PTP61F isoform 1 (Drosophila melanogaster)


name: (R)-mandelonitrile + UDP-alpha-D-glucose <=> (R)-prunasin + UDP + H(+)


name: Proteolytic degradation of ubiquitinated-Cdc25A (Homo sapiens)


name: inositol tetrakisphosphate phosphatase activity


name: ISL1 binds the SLIT2 gene enhancer (Homo sapiens)


name: crocetin + UDP-alpha-D-glucose = beta-D-glucosyl crocetin + UDP


name: Syk activation leads to SLP-76 activation (Homo sapiens)


name: RBBP8 gene expression is inhibited by E2F6 (Homo sapiens)


name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Caenorhabditis elegans)


name: NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP (Sus scrofa)


name: kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer (Bos taurus)


name: nonanal + NAD(+) + H2O => nonanoate + NADH + 2 H(+)


name: Trafficking of nonameric complex in the endocytic pathway (Sus scrofa)


name: L-histidyl-[protein] + ATP <=> N(tele)-phospho-L-histidyl-[protein] + ADP + H(+)


name: spermidine + O2 + H2O = N-(4-aminobutyl)-3-aminopropanal + H2O2 + NH4(+)


name: a globoside Gb4Cer + H2O <=> a globoside Gb3Cer + N-acetyl-beta-D-galactosamine


name: oxamate + carbamoyl phosphate = N-carbamoyl-2-oxoglycine + phosphate


name: GTP-bound RAC contributes to JNK activation (Caenorhabditis elegans)


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 (Sus scrofa)


name: The Ligand:GPCR:G12/13 complex dissociates (Bos taurus)


name: Activated MAPK phosphorylates RAF1 (Plasmodium falciparum)


name: Trimming of peptides by IRAP in endocytic vesicles (Rattus norvegicus)


name: N(alpha)-formyl-L-methionyl-L-serine + H2O <=> N(alpha)-formyl-L-methionine + L-serine


name: Association of procollagen type V (Xenopus tropicalis)


name: Association of procollagen type XVIII (Bos taurus)


name: protochlorophyllide b + 4 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O => protochlorophyllide a + 4 reduced [2Fe-2S]-[ferredoxin] + 2 O2 + 5 H(+)


name: PI is hydrolyzed to 1-acyl LPI by PLA2[11] (Rattus norvegicus)


name: ARID1 binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1 (Homo sapiens)


name: 5-dehydro-D-gluconate + NADP(+) <=> 2,5-didehydro-D-gluconate + NADPH + H(+)


name: Arresten binds integrin alpha1beta1 (Canis familiaris)


name: (2E)-dodecenedioyl-CoA + H2O = (3S)-hydroxydodecanedioyl-CoA


name: PI3K alpha, beta, gamma convert PIP2 to PIP3 (Caenorhabditis elegans)


name: 2-dehydro-D-glucose = cortalcerone + H2O


name: SHP2 dephosphorylates Tyr 992 on EGFR (Bos taurus)


name: (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + acetyl-CoA => 3-oxo-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + CoA


name: Phosphorylation of MDM4 by ATM (Homo sapiens)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR1 (Rattus norvegicus)


name: (E)-1-(glutathione-S-yl)-2-(1H-indol-3-yl)acetohydroximate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+) => (E)-(indol-3-yl)acetaldehyde oxime + glutathione + reduced [NADPH--hemoprotein reductase] + O2


name: Conversion of PA into DAG by PAP-1 (Sus scrofa)


name: nitroglycerin + NADPH <=> 1,2-dinitroglycerol + nitrite + NADP(+)


name: ATP2B4 binds to NOS1, inhibiting it (Gallus gallus)


name: Association of mTERF with the termination sequence (Mus musculus)


name: Formation of the MLL3 complex (Drosophila melanogaster)


name: CPT2 converts palmitoyl carnitine to palmitoyl-CoA (Sus scrofa)


name: CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Xenopus tropicalis)


name: all-trans-zeaxanthin + 4 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O => all-trans-beta-carotene + 4 reduced [2Fe-2S]-[ferredoxin] + 2 O2 + 4 H(+)


name: DAG stimulates protein kinase C-delta (Caenorhabditis elegans)


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Gallus gallus)


name: MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Danio rerio)


name: (2S,3R,11S)-aszonalenin + diphosphate => (S)-benzodiazepinedione + dimethylallyl diphosphate


name: 2-oxoglutarate + NADH + H(+) => 2-hydroxyglutarate + NAD(+)


name: Activated FGFR1:p-FRS bind to PPTN11 (Canis familiaris)


name: Terminal (3' end) cleavage of viral DNA (Homo sapiens)


name: L-seryl-[EGF-like domain protein] + UDP-alpha-D-glucose => 3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + UDP + H(+)


name: SLC46A1 transports FOLA from extracellular region to cytosol (Danio rerio)


name: 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+) => 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O


name: taurocholate + L-arginine <=> L-arginocholate + taurine


name: CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Dictyostelium discoideum)


name: SFTPB gene produces pro-SFTPB protein (Homo sapiens)


name: PGA2 is dehydrated to 15d-PGA2 (Homo sapiens)


name: L-cysteinyl-tRNA(Cys) + AMP + diphosphate => tRNA(Cys) + L-cysteine + ATP


name: L-proline + L-tryptophan + 2 ATP + NADPH <=> (S)-3-(indol-3-ylmethyl)-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + 2 AMP + 2 diphosphate + NADP(+) + H2O + H(+)


name: 4-O-deacetylvindoline + succinate + CO2 => deacetoxyvindoline + 2-oxoglutarate + O2


name: protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity


name: a beta-D-glucosylceramide(in) + ATP + H2O => a beta-D-glucosylceramide(out) + ADP + phosphate + H(+)


name: (2R)-3-(3,4-dihydroxyphenyl)lactate + NADP(+) => 3-(3,4-dihydroxyphenyl)pyruvate + NADPH + H(+)


name: ADRB2:Catecholamine binds ARRB1, ARRB2 (Homo sapiens)


name: RHOD:GTP translocates to the endosome membrane (Xenopus tropicalis)


name: PRODH2 oxidises HPRO to 1PYR-3OH-5COOH (Saccharomyces cerevisiae)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane (Saccharomyces cerevisiae)


name: G alpha (z) auto-inactivates by hydrolysing GTP to GDP (Homo sapiens)


name: a jasmonate + an L-alpha-amino acid + ATP <=> a jasmonyl-L-amino acid + AMP + diphosphate + H(+)


name: Ubiquitinated Orc1 enters the cytosol (Plasmodium falciparum)


name: (R)-lipoate(out) + 2 Na(+)(out) => (R)-lipoate(in) + 2 Na(+)(in)


name: S-adenosyl-L-homocysteine(out) + S-adenosyl-L-methionine(in) <=> S-adenosyl-L-homocysteine(in) + S-adenosyl-L-methionine(out)


name: an N,N-dimethylornithine lipid + S-adenosyl-L-homocysteine + H(+) => an N-methylornithine lipid + S-adenosyl-L-methionine


name: 13-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2


name: Phosphorylation of INFAR1 by TYK2 (Xenopus tropicalis)


name: ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 (Sus scrofa)


name: 8-oxo-dADP + H2O = 8-oxo-dAMP + phosphate + H(+)


name: 7-deoxyloganetic aldehyde + reduced [NADPH--hemoprotein reductase] + O2 = 7-deoxyloganetate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)


name: hyponitrous acid + 2 NADH + 2 H(+) => 2 hydroxylamine + 2 NAD(+)


name: Prolactin-releasing hormone receptor binds PRH (Canis familiaris)


name: Collagen type VII degradation by MMP1,2,3 (Homo sapiens)


name: (2S)-liquiritigenin + reduced [NADPH--hemoprotein reductase] + O2 <=> (2R,3S)-2,4',7-trihydroxyisoflavanone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: gastric inhibitory polypeptide receptor binding


name: dihydropyriculariol + A <=> pyriculariol + AH2


name: LTN1 K48 polyubiquitinates the nascent peptide in NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide (Saccharomyces cerevisiae)


name: STAT1,STAT3,STAT6 phosphorylation (Homo sapiens)


name: tryptamine + AH2 + O2 <=> 4-hydroxytryptamine + A + H2O


name: furfural + hydrogen cyanide <=> (2R)-2-(furan-2-yl)-2-hydroxyacetonitrile


name: Aquaporin-4 passively transports water out of cell (Rattus norvegicus)


name: L-aspartyl-tRNA(Asp) + L-arginyl-tRNA(Arg) = cyclo(L-arginyl-L-aspartyl) + tRNA(Asp) + tRNA(Arg) + 2 H(+)


name: (25S)-3-oxocholest-4-en-26-oyl-CoA + A <=> 3-oxo-cholest-4,24-dien-26-oyl-CoA + AH2


name: phosphonoacetaldehyde + H2O2 + NH4(+) => (2-aminoethyl)phosphonate + O2 + H2O


name: HYAL1-4 hydrolyze chondroitin chains (Danio rerio)


name: MPI isomerises Fru6P to Man6P (Caenorhabditis elegans)


name: activation of nitric oxide metabolic process


name: RHOB GEFs activate RHOB (Caenorhabditis elegans)


name: N-acetyl-D-glucosamine 6-phosphate + CDP + H(+) => N-acetyl-D-glucosamine + CTP


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + dodecanoyl-CoA => 1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphate + CoA


name: RAB3IP stimulates nucleotide exchange on RAB8A (Bos taurus)


name: 4-hydroxy-3-(all-trans-nonaprenyl)benzoate + H(+) <=> 2-all-trans-nonaprenylphenol + CO2


name: SHP1 and SHP2 dephosphorylate Y628 of IL3RB (Canis familiaris)


name: negative regulation of macrophage colony-stimulating factor signaling pathway


name: Fusion of COPII vesicle with Golgi complex (Bos taurus)


name: SUMOylation of NR1I2 with SUMO3 (Mus musculus)


name: maleate(in) + citrate(out) <=> maleate(out) + citrate(in)


name: (2E)-3-methyl-5-phosphooxypent-2-enoate + H(+) => isopentenyl phosphate + CO2


name: CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Caenorhabditis elegans)


name: BRCA1 forms a heterodimer with BARD1 (Rattus norvegicus)


name: (2S)-2-amino-4-deoxychorismate + L-glutamine + H2O <=> 4-amino-4-deoxychorismate + L-glutamate + NH4(+)


name: p75NTR and RHOA-GDI interact (Xenopus tropicalis)


name: OPLAH hydrolyses OPRO to L-Glu (Homo sapiens)


name: PTGS1 dimer binds PTGS1 Inhibitors (Canis familiaris)


name: KBTBD7:CUL3:RBX1 ubiquitinates NF1 (Sus scrofa)


name: (+)-copalyl diphosphate => isopimara-8(14),15-diene + diphosphate


name: RNF41 binds neuregulin-activated ERBB3 (Bos taurus)


name: fibrin multimer, crosslinked -> fibrin digestion products (plasmin) (Mus musculus)


name: Addition of nucleotides between position +11 and +30 (Canis familiaris)


name: PTPN11 binds p-Y759-IL6ST (Gallus gallus)


name: ubiquinone-8 + formate(out) + 2 H(+)(in) <=> ubiquinol-8 + CO2(out) + H(+)(out)


name: L-Glutamine transport into neurons (Homo sapiens)


name: 3-dehydro-4-O-phospho-L-erythronate + NADH + H(+) => 4-O-phospho-D-threonate + NAD(+)


name: Formation of the MLL2 complex (Homo sapiens)


name: COMT transfers Met to DA to form 3MT (Bos taurus)


name: benzoyl-CoA + AMP + diphosphate => benzoate + ATP + CoA


name: NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP (Rattus norvegicus)


name: Growth hormone binds the growth hormone receptor (Danio rerio)


name: 3-(all-trans-decaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine <=> 2-methoxy-6-(all-trans-decaprenyl)phenol + S-adenosyl-L-homocysteine + H(+)


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + an acyl-CoA => 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + CoA


name: (-)-4'-methoxycyclopeptine + 2 AMP + S-adenosyl-L-homocysteine + 2 diphosphate + 2 H(+) => O-methyl-L-tyrosine + anthranilate + S-adenosyl-L-methionine + 2 ATP


name: CDC14A,B bind MAPK6 (Schizosaccharomyces pombe)


name: EPS15 and HGS bind ubiquitinated MET (Bos taurus)


name: Aquaporin-3 passively transports water out of cell (Canis familiaris)


name: thymine + NADPH + H(+) => 5,6-dihydrothymine + NADP(+)


name: D-glycero-beta-D-manno-heptose 1-phosphate + UTP + H(+) => UDP-D-glycero-beta-D-manno-heptose + diphosphate


name: pregnan-21-ol + NAD(+) <=> pregnan-21-al + NADH + H(+)


name: 14-deacetyl astellolide A + CoA => dideacetyl astellolide A + acetyl-CoA


name: ATP-dependent protein-DNA unloader activity


name: MET dimers autophosphorylate (Bos taurus)


name: SRXN1 reduces hyperoxidized PRDX1 dimer (Gallus gallus)


name: chlorothalonil + H2O => 4-hydroxychlorothalonil + chloride + 2 H(+)


name: PTGS2 dimer oxidises EPA to PGH3 (Sus scrofa)


name: vitamin B6 transmembrane transporter activity


name: Dissociation of CaM and CAMK2 autophosphorylation (Caenorhabditis elegans)


name: ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA (Bos taurus)


name: MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed (Rattus norvegicus)


name: L-threonyl-[myosin light chain] + phosphate => O-phospho-L-threonyl-[myosin light chain] + H2O


name: atrochrysone carboxyl-[ACP] + H2O <=> atrochrysone carboxylate + holo-[ACP] + H(+)


name: PG is hydrolyzed to 1-acyl LPG by PLA2G2A (Homo sapiens)


name: a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)


name: a 1-O-alkyl-2-acetyl-sn-glycerol + CDP-choline => a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: p-S207 KARS1 dimer translocates to the nucleus (Homo sapiens)


name: ZEB1 recruits TLE1 and HDAC1/2 to CDH1 gene promoter (Homo sapiens)


name: 2-hexyl-5-heptylresorcinol + reduced [NADPH--hemoprotein reductase] + O2 = 2-hexyl-5-(7-hydroxyheptyl)resorcinol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) (Rattus norvegicus)


name: Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 (Dictyostelium discoideum)


name: IL31:IL31RA:JAK1 binds OSMR:JAK1 (Canis familiaris)


name: Clustering of Integrin alphaIIb beta3 complexes (Sus scrofa)


name: (13S)-edaxadiene + diphosphate => tuberculosinyl diphosphate + H2O


name: apelin-17 + H2O => apelin-16 + L-phenylalanine


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + H2O => sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)


name: chondroitin 4'-sulfate + n adenosine 3',5'-bisphosphate + n H(+) => chondroitin beta-D-glucuronate + n 3'-phosphoadenylyl sulfate


name: all-trans-4-hydroxy-13,14-dihydroretinoate + reduced [NADPH--hemoprotein reductase] + O2 => all-trans-4-oxo-13,14-dihydroretinoate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Mus musculus)


name: APAF1:CYCS binds APIP (Rattus norvegicus)


name: SEMA6D binds to PLXNA1:TREM2:DAP12 (Mus musculus)


name: MYC,MYCN binding to CD274 gene (Homo sapiens)


name: ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Canis familiaris)


name: MDH2 dimer dehydrogenates MAL (Caenorhabditis elegans)


name: (E)-hept-2-enal + NAD(+) + H2O = (E)-hept-2-enoate + NADH + 2 H(+)


name: (2R,3Z)-phycocyanobilin + 4 oxidized [2Fe-2S]-[ferredoxin] => biliverdin IXalpha + 4 reduced [2Fe-2S]-[ferredoxin] + 4 H(+)


name: TBK1 phosphorylates STAT6 at Ser407 (Sus scrofa)


name: ROBO signaling pathway involved in muscle cell attraction


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] (Drosophila melanogaster)


name: IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 (Bos taurus)


name: 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate + H(+)


name: 1,4-alpha-glucan is converted to glucanotrehalose (Mycobacterium tuberculosis)


name: Dual mechanism MAP2K inhibitors bind MAP2Ks (Homo sapiens)


name: Activation of PAK by Rac1 (Mus musculus)


name: CYP4F12 18-hydroxylates ARA (Canis familiaris)


name: Hydrolysis of PC to PA by PLD (Schizosaccharomyces pombe)


name: KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Mus musculus)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho]-glycerol + CoA


name: prostaglandin D2 = prostaglandin J2 + H2O


name: a 2-hydroxyflavanone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => a flavanone + reduced [NADPH--hemoprotein reductase] + O2


name: Activated type I receptor phosphorylates SMAD2/3 directly (Rattus norvegicus)


name: Collagen type XXV ectomain shedding (Mus musculus)


name: SRC-1 phosphorylates PTK2-beta (Sus scrofa)


name: a triacyl-sn-glycerol + CoA => a 2,3-diacyl-sn-glycerol + an acyl-CoA


name: WIPI2 binds ATG12:ATG5:ATG16L (Homo sapiens)


name: 1,2-diacyl-glycero-3-phosphocholine + an N-acylsphing-4-enine <=> a sphingomyelin + a 1,2-diacylglycerol


name: 5-O-(ADP-D-ribosyl)-L-glutamyl-[protein] + H2O <=> L-glutamyl-[protein] + ADP-D-ribose + H(+)


name: N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine => 1-O-acyl-N-(acetyl)-sphing-4-enine + a 2-acyl-sn-glycero-3-phosphocholine


name: DHAP is converted to G3P by GPD1/GPD1L (Canis familiaris)


name: RAC1 GDIs block activation of RAC1 (Xenopus tropicalis)


name: tRNA queuosine galactosyltransferase activity


name: ribostamycin + ATP <=> 4'-adenylylribostamycin + diphosphate


name: Phosphorylated BMAL1:CLOCK,NPAS2 and coactivators positively regulate expression of Period-2 (PER2) (Homo sapiens)


name: heptan-2-one + NADPH + O2 + H(+) = pentyl acetate + NADP(+) + H2O


name: ABC-type iron-sulfur cluster transporter activity


name: petunidin 3-O-beta-D-galactoside + UDP => petunidin + UDP-alpha-D-galactose


name: FOXA1 and GATA3 bind to CCND1 promoter (Rattus norvegicus)


name: SLC2A5 transports fructose from extracellular region to cytosol (Bos taurus)


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GM4 (d18:1(4E)) + CMP + H(+)


name: Phosphorylation of PKC-theta (Homo sapiens)


name: Loss of SAR1B GTPase (Rattus norvegicus)


name: (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => a (9Z,11E,13E,15Z)-octadecatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: TRPA1 tetramer binds TRPA1 antagonists (Saccharomyces cerevisiae)


name: hydroxymethylbilane => uroporphyrinogen I + H2O (Gallus gallus)


name: CHST15 transfers sulfate to (6-)GalNAc-4-sulfate (Rattus norvegicus)


name: Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Gallus gallus)


name: 2 L-tryptophan <=> cyclo(L-Trp-L-Trp) + 2 H2O


name: 3,6-dichloropyridine-2,5-diol + FADH2 + O2 => 6-chloro-3-hydroxypyridine-2,5-dione + FAD + chloride + H2O + 2 H(+)


name: a (3R)-3-[(carboxymethyl)amino]fatty acid + 2 2-oxoglutarate + 2 O2 => a (3R)-3-isocyanyl-fatty acid + 2 succinate + 3 CO2 + 2 H2O


name: IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation  (Mus musculus)


name: JNK phosphorylates BIM, BAD and other targets (Canis familiaris)


name: NT5C3B hydrolyses 7MGP to 7MG (Canis familiaris)


name: Ag(+)(out) + ADP + phosphate + H(+) => Ag(+)(in) + ATP + H2O


name: Protein Kinase B/Akt phosphorylates BRF1 (Danio rerio)


name: ATP7A transports cytosolic Cu2+ to phagosomal lumen (Sus scrofa)


name: N-terminal L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine <=> N-terminal N-methyl-L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)


name: SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Gallus gallus)


name: N-(1-deoxy-beta-D-fructopyranos-1-yl)glycine + O2 + H2O => (1-deoxy-D-fructos-1-yl)amine + glyoxylate + H2O2


name: The NEXT complex and ZC3H18 bind CBCA:m7GpppN-RNA (Bos taurus)


name: cyanidin 3,5-di-O-beta-D-glucoside + (E)-sinapate => cyanidin 3-O-beta-D-glucoside + 1-O-(trans-sinapoyl)-beta-D-glucose


name: gypsogenin + UDP-alpha-D-glucose = gypsogenin 28-beta-D-glucoside + UDP


name: L-valine(out) + L-glutamine(in) + Na(+)(out) = L-valine(in) + L-glutamine(out) + Na(+)(in)


name: CYP2W1 oxidises INDOL (Caenorhabditis elegans)


name: PXN binds p-6Y,S732-PTK2 (Gallus gallus)


name: Generation of a DNA double strand break (Gallus gallus)


name: ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Sus scrofa)


name: 1-hexadecanoyl-sn-glycero-3-phosphate + (9Z)-hexadecenoyl-CoA = 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphate + CoA


name: NOTCH1 PEST domain mutants stimulate HES5 transcription (Homo sapiens)


name: 2 reduced [2Fe-2S]-[ferredoxin] + Na(+)(in) + NAD(+) + H(+) => 2 oxidized [2Fe-2S]-[ferredoxin] + Na(+)(out) + NADH


name: USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA (Saccharomyces cerevisiae)


name: N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + succinyl-CoA = N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[protein] + CoA


name: PA is converted to CDP-DAG by CDS1 (Xenopus tropicalis)


name: a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose => a beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl derivative + GDP + H(+)


name: p-T153 USF1 dimer binds the TYR promoter (Homo sapiens)


name: cyathatriol + acetyl-CoA = 11-O-acetylcyathatriol + CoA


name: all-trans-13,14-dihydroretinol + NAD(+) <=> all-trans-13,14-dihydroretinal + NADH + H(+)


name: dehydroepiandrosterone 3-sulfate(out) + n H(+)(out) => dehydroepiandrosterone 3-sulfate(in) + n H(+)(in)


name: Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Homo sapiens)


name: CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (Mus musculus)


name: a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP


name: (7Z,10Z,13Z)-hexadecatrienoyl-CoA + phytol => (7Z,10Z,13Z)-hexadecatrienoate phytyl ester + CoA


name: ADIPOQ trimer binds ADIPOR dimers (Sus scrofa)


name: carbamoyl-phosphate synthase (ammonia) activity


name: CDP-choline + 1,2-di-(9Z-octadecenoyl)-sn-glycerol => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: Endocytosis of TLR4:LY96:LPS:CD14 (Canis familiaris)


name: Formation of the IGF:IGFBP5:ALS complex (Danio rerio)


name: CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane (Canis familiaris)


name: octadecanoate ester + H2O => an aliphatic alcohol + octadecanoate + H(+)


name: ACAT2 condenses 2 Ac-CoA to form ACA-CoA (Schizosaccharomyces pombe)


name: chorismate + inosine + phosphoenolpyruvate <=> futalosine


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine <=> a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP + H(+)


name: PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane (Mus musculus)


name: L-threo-3-phenylserine = 3-phenylpyruvate + NH4(+)


name: 3-oxodecanedioyl-CoA + NADH + H(+) => (3S)-hydroxydecanedioyl-CoA + NAD(+)


name: cytidine(34) in mitochondrial tRNA + S-adenosyl-L-methionine => 5-methylcytidine(34) in mitochondrial tRNA + S-adenosyl-L-homocysteine + H(+)


name: Caspase-mediated cleavage of claspin (Gallus gallus)


name: CYP11B2 oxidises 11DCORST to CORST (Homo sapiens)


name: alpha-D-mannosyl-(1->3)-alpha-D-galactosyl-diphospho-di-trans,octa-cis-undecaprenol + GDP-alpha-D-mannose => alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: 15-cis-phytoene + A <=> all-trans-phytofluene + AH2


name: I(1,4,5)P3 binds ITPR3 tetramer (Bos taurus)


name: hexadecanoyl-CoA + H2O <=> S-hexadecanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)


name: SMURF1 gene expression is stimulated by RUNX2 (Homo sapiens)


name: Membrane-bound CDH11 is cleaved to produce secreted CDH11 isoform (Canis familiaris)


name: UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG (Dictyostelium discoideum)


name: GAB1 binds phosphatidylinositol-3,4,5-trisphosphate (Homo sapiens)


name: 1-(9Z-octadecenoyl)-2-(8Z,11Z,14Z-eicosatrienoyl)-sn-glycero-3-phospho-1D-myo-inositol + H2O = 2-(8Z,11Z,14Z-eicosatrienoyl)-sn-glycero-3-phospho-1D-myo-inositol + (9Z)-octadecenoate + H(+)


name: 13,14-epoxy-(7Z,10Z,16Z,19Z)-docosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2


name: sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-acyl-sn-glycero-3-phosphoethanolamine + CoA


name: cremeomycin + AH2 <=> 2-hydroxy-4-methoxybenzoate + N2 + A


name: (22S,24R)-22-hydroxy-5alpha-ergostan-3-one + reduced [NADPH--hemoprotein reductase] + O2 => 3-dehydro-6-deoxoteasterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: a fatty acyl-CoA + sphing-4-enine => an N-acylsphing-4-enine + CoA + H(+)


name: 5-methoxytryptamine + O2 + H2O <=> 5-methoxyindoleacetaldehyde + H2O2 + NH4(+)


name: 5-methoxy-2-methyl-3-(all-trans-octaprenyl)benzene-1,4-diol + prephenate + A + H(+) => 3-demethylubiquinol-8 + 3-phenylpyruvate + AH2 + CO2


name: (11R)-dihydroartemisinate + NADH + 2 H(+) => (11R)-dihydroartemisinic aldehyde + NAD(+) + H2O


name: C3 binds C3 inhibitors (Rattus norvegicus)


name: PRKCA/Q phosphorylate RGS9-1:GN5B:RGS9BP (Homo sapiens)


name: G6PD multimers dehydrogenate G6P (Rattus norvegicus)


name: D-lysine + 2-oxoglutarate = 6-amino-2-oxohexanoate + D-glutamate


name: hydrogen sulfide + acetyl-CoA = thioacetate + CoA


name: heptyl sulfate + 2-oxoglutarate + O2 <=> heptanal + sulfate + succinate + CO2 + H(+)


name: A4GALT transfers galactose to LacCer (Sus scrofa)


name: a (9Z)-octadecenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 6-hydroxyhexanoate + NADP(+) = 6-oxohexanoate + NADPH + H(+)


name: SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol (Mus musculus)


name: 3beta-hydroxy-5-androstene-7,17-dione + NADPH + H(+) => 3beta,7beta-dihydroxyandrost-5-en-17-one + NADP(+)


name: 3,N(4)-ethenocytosine + a 2'-deoxyribose 5'-monophosphate in double-stranded DNA => a 3,N(4)-etheno-2'-deoxycytidine in double-stranded DNA + H2O


name: N-hydroxy-L-dihomomethionine + reduced [NADPH--hemoprotein reductase] + O2 <=> N,N-dihydroxy-L-dihomomethionine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + H2O <=> 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + phosphate


name: HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ (Sus scrofa)


name: Polyubiquitinated TRAF6 binds the TAK1 complex (Canis familiaris)


name: JAK3 binds JAK3 inhibitors (Rattus norvegicus)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Sus scrofa)


name: Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one (Mus musculus)


name: NAD-dependent protein lipoamidase activity


name: AP-2 directly binds some endocytic cargo (Mus musculus)


name: imidazole-4-acetate + NADH + 2 H(+) => imidazole-4-acetaldehyde + NAD(+) + H2O


name: SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Homo sapiens)


name: IRE1 binds IRE1 forming dimer (Rattus norvegicus)


name: Phosphorylation and activation of eIF4G by activated S6K1 (Gallus gallus)


name: negative regulation of exonuclease activity


name: (5'S,6'R)-C-glycyluridine + O2 = uridine-5'-carboxamide + CO2 + H2O


name: MST1 dimer:MST1R dimer binds MST1R dimer (Bos taurus)


name: Polyubiquitinated NRIF migrates to the nucleus (Rattus norvegicus)


name: CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly (Schizosaccharomyces pombe)


name: Unwinding of DNA for the Nascent Transcript: Second Transition (Saccharomyces cerevisiae)


name: beta-alanyl-[peptidyl-carrier protein] + dopamine = beta-alanyl-dopamine + holo-[peptidyl-carrier protein] + H(+)


name: SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) (Danio rerio)


name: p-T774-PKN1 phosphorylates CDC25C (Caenorhabditis elegans)


name: 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O = 5-deoxy-D-glucuronate + H(+)


name: Exchange of oxygen with sulfur in MoCo (Drosophila melanogaster)


name: 2xPPCS ligates PPanK with Cys (Canis familiaris)


name: lanosterol + S-adenosyl-L-methionine => eburicol + S-adenosyl-L-homocysteine + H(+)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + NADP(+) = 6-lactoyl-5,6,7,8-tetrahydropterin + NADPH + H(+)


name: (R)-pantothenate + ADP + phosphate + H(+) => (R)-pantoate + beta-alanine + ATP


name: The proteasome degrades the K48-polyubiquitinated alanine-tailed nascent peptide (Rattus norvegicus)


name: UBA1 adenylates ubiquitin in the nucleoplasm (Drosophila melanogaster)


name: L-alanyl-L-prolylglycine(out) + H(+)(out) => L-alanyl-L-prolylglycine(in) + H(+)(in)


name: all-trans-8'-apo-beta-carotenal + O2 <=> 2,6-dimethyldeca-2,4,6,8-tetraenedial + 13-apo-beta-carotenone


name: Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Homo sapiens)


name: AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Dictyostelium discoideum)


name: positive regulation of cellotriose transport


name: Elastic fibres bind associated proteins (Homo sapiens)


name: SORL1 transports APP(18-770) from endosome lumen to Golgi lumen (Homo sapiens)


name: orsellinate + (2E,6E)-farnesyl diphosphate = ilicicolinate B + diphosphate


name: 3-oxohexadecanoyl-CoA + NADPH + H(+) <=> (3R)-hydroxyhexadecanoyl-CoA + NADP(+)


name: Electron transfer from ubiquinol to cytochrome c of complex III (Bos taurus)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O => sn-glycerol 3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)


name: LIFR:JAKs bind gp130:JAKs:CNTFR (Gallus gallus)


name: PS is hydrolyzed to 1-acyl LPS by PLA2[15] (Mus musculus)


name: ASICs bind STOML3, (STOM) (Canis familiaris)


name: "ultra-long-chain fatty acid omega-hydroxylase"


name: N,N-dimethylaniline + NADPH + O2 + H(+) = N,N-dimethylaniline N-oxide + NADP(+) + H2O


name: ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Canis familiaris)


name: IDUA hydrolyses Heparan sulfate chain(6) (Dictyostelium discoideum)


name: I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus (Xenopus tropicalis)


name: keto-L-sorbose + NADH + H(+) => L-iditol + NAD(+)


name: SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol (Gallus gallus)


name: (E)-5-hydroxyferulate + S-adenosyl-L-methionine = (E)-sinapate + S-adenosyl-L-homocysteine + H(+)


name: Caspase-mediated cleavage of occludin (Sus scrofa)


name: SUMOylation of NR1H4 with SUMO1 (Bos taurus)


name: PTGS1,2 dimers bind PTGS Inhibitors (Rattus norvegicus)


name: L,L-cystathionine + H2O <=> 2-oxobutanoate + L-cysteine + NH4(+)


name: CDH1 forms homotypic trans-dimers (Bos taurus)


name: JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Bos taurus)


name: Formation of the PA28gamma-20S proteasome (Mus musculus)


name: Formation of Okazaki fragments (Schizosaccharomyces pombe)


name: SecA:SecYEG transports proteins from cytosol to periplasmic space (Homo sapiens)


name: 24,25-dihydrolanosterol + reduced [NADPH--hemoprotein reductase] + O2 = 32-hydroxy-24,25-dihydrolanosterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidin-2-one + O2 = 5-[(4-hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + H2O2 + H(+)


name: 15-cis-4,4'-diapophytoene + 2 diphosphate => 2 (2E,6E)-farnesyl diphosphate


name: spherical HDL and SR-BI receptor form a complex at the cell surface (Sus scrofa)


name: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O => N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + a 1,2-diacyl-sn-glycero-3-phosphate + H(+)


name: 8-demethyl-8-(2,3-di-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + S-adenosyl-L-methionine = 8-demethyl-8-(2,3,4-tri-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + S-adenosyl-L-homocysteine + H(+)


name: stretch-activated, monoatomic cation-selective, calcium channel activity involved in regulation of action potential


name: NK13650 D + L-aspartate + ATP <=> NK13650 C + AMP + diphosphate + H(+)


name: p-T774-PKN1 binds CDC25C (Dictyostelium discoideum)


name: 8-oxo-dADP + H2O <=> 8-oxo-dAMP + phosphate + H(+)


name: carbohydrate:monoatomic cation symporter activity


name: taurodeoxycholate(in) + ATP + H2O <=> taurodeoxycholate(out) + ADP + phosphate + H(+)


name: (3S)-hydroxyhexanoyl-CoA <=> (2E)-hexenoyl-CoA + H2O


name: Importin-8 imports AGO2:miRNA into the nucleus (Rattus norvegicus)


name: Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 (Bos taurus)


name: PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Drosophila melanogaster)


name: RUNX3 binds the BCL2L11 (BIM) gene (Homo sapiens)


name: 7(1)-hydroxychlorophyll a + NAD(+) => chlorophyll b + NADH + H(+)


name: PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter (Bos taurus)


name: N-terminal N(alpha)-acetyl-L-methionyl-L-threonyl-[protein] + CoA + H(+) => N-terminal L-methionyl-L-threonyl-[protein] + acetyl-CoA


name: 8,9-EET is hydrolysed to 8.9-DHET by EPHX2 (Dictyostelium discoideum)


name: DSCAM/DSCAML1 homodimerization (Mus musculus)


name: DENND5A,B exchange GTP for GDP on RAB39 (Mus musculus)


name: FAHD1 dimer hydrolyses OA to PYR (Homo sapiens)


name: pheophorbide a(in) + ATP + H2O <=> pheophorbide a(out) + ADP + phosphate + H(+)


name: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADPH + O2 + H(+) <=> 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP(+) + H2O


name: Formation of ORC(1-6) complex (Sus scrofa)


name: adenosine(1914)/adenosine(1915) in 18S rRNA + 4 S-adenosyl-L-methionine => N(6)-dimethyladenosine(1914)/N(6)-dimethyladenosine(1915) in 18S rRNA + 4 S-adenosyl-L-homocysteine + 4 H(+)


name: 3,3'-diiodothyronamine + iodide + A + H(+) => 3,3',5'-triiodothyronamine + AH2


name: NFKBIA variant is not phosphorylated within IkBA:NF-kappaB (Homo sapiens)


name: formate + ATP <=> formyl phosphate + ADP


name: CPO transforms COPRO3 to PPGEN9 (Homo sapiens)


name: (Z)-3-hydroxypropyl glucosinolate + H2O <=> (Z)-3-hydroxypropyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)


name: (2E)-geranyl diphosphate = beta-phellandrene + diphosphate


name: ENPP6 hydrolyzes lysophosphatidylcholine (Caenorhabditis elegans)


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Plasmodium falciparum)


name: SLC2A6,8,10,12 transport Glc from extracellular region to cytosol (Dictyostelium discoideum)


name: IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B (Mus musculus)


name: SULTs transfer (SO4)2- group to PREG (Homo sapiens)


name: N(6)-(2E)-butenoyl-L-lysyl-[protein] + H2O => (2E)-2-butenoate + L-lysyl-[protein]


name: 9,10-epoxyoctadecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 18-hydroxy-9,10-epoxy-octadecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: stimulation of monophenol oxygenase activity


name: Receptor CCR7 binds CCL19 and 21 ligands (Gallus gallus)


name: NRPE dissociates to atRAL and PE (Homo sapiens)


name: GRSF1 unwinds quadruplex G regions in RNA (Homo sapiens)


name: precorrin-1 + S-adenosyl-L-methionine <=> precorrin-2 + S-adenosyl-L-homocysteine


name: L-type Calcium Channels close in pancreatic beta cells (Homo sapiens)


name: anthraniloyl-CoA + 2 NADPH + O2 + 2 H(+) <=> 2-amino-5-oxocyclohex-1-enecarbonyl-CoA + 2 NADP(+) + H2O


name: AKRs reduce RBP2:atRAL to RBP2:atROL (Bos taurus)


name: propanal + NADP(+) + H2O = propanoate + NADPH + 2 H(+)


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Bos taurus)


name: ERBB2 ECD mutants bind trastuzumab (Homo sapiens)


name: p-Y701-STAT1:p-Y705-STAT3 translocates from the cytosol to the nucleus (Dictyostelium discoideum)


name: (2R)-hydroxy-4-methylpentanoate + NADP(+) <=> 4-methyl-2-oxopentanoate + NADPH + H(+)


name: apo-L-cysteinyl(155)-[phycoerythrocyanin beta-subunit] + (2R,3E)-phycocyanobilin => phycocyanobilin-L-cysteinyl(155)-[phycoerythrocyanin beta-subunit]


name: [Wnt protein]-O-(9Z)-hexadecenoyl-L-serine + CoA => [Wnt protein]-L-serine + (9Z)-hexadecenoyl-CoA


name: (R)-mevalonate + ATP <=> (R)-3-phosphomevalonate + ADP + H(+)


name: 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + UDP-alpha-D-glucuronate => 20-O-(beta-D-glucuronosyl)-(5Z,8Z,11Z,14Z)-eicosatetraenoate + UDP + H(+)


name: extrinsic apoptotic signaling pathway via B cell antigen receptor


name: taurocholate(in) + ATP + H2O = taurocholate(out) + ADP + phosphate + H(+)


name: an aromatic L-alpha-amino acid + 4-methylsulfanyl-2-oxobutanoate => an aromatic oxo-acid + L-methionine


name: Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Gallus gallus)


name: Formation of CD4:Nef:AP-2 Complex:v-ATPase Complex (Homo sapiens)


name: 3-oxo-(11Z)-octadecenoyl-CoA + CO2 + CoA => (9Z)-hexadecenoyl-CoA + malonyl-CoA + H(+)


name: 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidin-2-one + O2 <=> 5-[(4-hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + H2O2 + H(+)


name: L-proline + NADP(+) => 1-pyrroline-2-carboxylate + NADPH + H(+)


name: guanosine 3',5'-bis(diphosphate) + AMP => GDP + ATP


name: (2E,6E)-farnesyl diphosphate + H2O => presilphiperfolan-8beta-ol + diphosphate


name: CLCN4/5/6 exchange Cl- for H+ (Caenorhabditis elegans)


name: RNA Polymerase II Promoter Opening: First Transition (Gallus gallus)


name: Autocatalytic activation of proMMP13 (Rattus norvegicus)


name: Ubiquitinated Orc1 is degraded by the proteasome (Saccharomyces cerevisiae)


name: Cleavage of Procaspase-7 by the apoptosome (Homo sapiens)


name: GMPPB converts Mannose-1-phosphate to GDP-Mannose (Canis familiaris)


name: 21-hydroxyprogesterone + 2 reduced [adrenodoxin] + O2 + 2 H(+) = 19-hydroxy-11-deoxycorticosterone + 2 oxidized [adrenodoxin] + H2O


name: 3,5-dimethylbenzyl alcohol + O2 => 3,5-dimethylbenzaldehyde + H2O2


name: 2-hexyl-5-pentylresorcinol + reduced [NADPH--hemoprotein reductase] + O2 => 2-hexyl-5-(5-hydroxypentyl)resorcinol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: O-atom dealkylation of dextromethorphan (Drosophila melanogaster)


name: p-IRF7 dimer interacts with coactivator CBP/p300 (Xenopus tropicalis)


name: ligand-gated monoatomic cation channel activity


name: chaperone-mediated protein complex assembly


name: D-glyceraldehyde 3-phosphate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O = (2R)-3-phosphoglycerate + 2 reduced [2Fe-2S]-[ferredoxin] + 3 H(+)


name: POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) (Homo sapiens)


name: pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Homo sapiens)


name: Expression of Diphosphomevalonate Decarboxylase (MVD) (Homo sapiens)


name: SLC22A18 exchanges extracellular organic cations for cytosolic H+ (Sus scrofa)


name: mRNA regulatory element binding translation repressor activity


name: ACO1, IREB2 bind IREs in TFRC, ALAD, FTL, FTH1 mRNAs (Homo sapiens)


name: CYP7B1 7-hydroxylates 25OH-CHOL (Canis familiaris)


name: a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA => a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA


name: Insulin binds the insulin receptor (Danio rerio)


name: a 2'-deoxyribonucleoside 5'-phosphate + H2O => a 2'-deoxyribonucleoside + phosphate


name: DAG and Ca+2 bind to PKC and tether it to membrane (Bos taurus)


name: N-terminal S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein] + a glycerophospholipid <=> N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein] + a 2-acyl-sn-glycero-3-phospholipid + H(+)


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Rattus norvegicus)


name: POLK and POLZ cooperate in elongation of mispaired primer termini (Rattus norvegicus)


name: a ganglioside SM1a + 3'-phosphoadenylyl sulfate => a ganglioside SB1a + adenosine 3',5'-bisphosphate + H(+)


name: IL34:CSF1 binds CSF1R (Rattus norvegicus)


name: RAC2:GTP binds NOX2 complex (Homo sapiens)


name: HMGCR dimer reduces bHMG-CoA to MVA (Dictyostelium discoideum)


name: POLK and POLZ cooperate in elongation of mispaired primer termini (Schizosaccharomyces pombe)


name: N-acetyl-alpha-neuraminate(out) + 2 Na(+)(out) => N-acetyl-alpha-neuraminate(in) + 2 Na(+)(in)


name: DRD2 antagonist drugs bind to DRD2 (Canis familiaris)


name: ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate (Bos taurus)


name: 3-O-beta-D-glucosyl-D-glucuronate + phosphate => aldehydo-D-glucuronate + alpha-D-glucose 1-phosphate


name: alpha-L-2OAcRha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP-alpha-D-abequose => alpha-D-Abe-(1->3)-alpha-L-Rha2OAc-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP + H(+)


name: MAOA:FAD deaminates 3MT to HVA (Dictyostelium discoideum)


name: RHOB binds effectors at the plasma membrane (Sus scrofa)


name: (2E)-geranyl diphosphate => sabinene + diphosphate


name: RNF41 ubiquitinates activated ERBB3 (Danio rerio)


name: 2-thiocytidine(32) in tRNA + L-cysteinyl-[cysteine desulfurase] + A + AMP + diphosphate + H(+) => cytidine(32) in tRNA + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] + AH2 + ATP


name: 15-methylhexadecasphinganine + a fatty acyl-CoA <=> an N-acyl-15-methylhexadecasphinganine + CoA + H(+)


name: Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)


name: SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Sus scrofa)


name: MUC20 binds MET and inhibits GRB2 binding (Bos taurus)


name: Phosphorylation of MEF2 proteins by p38 (Caenorhabditis elegans)


name: ERCC3-facilitated RNA Pol II backtracking in TC-NER (Homo sapiens)


name: a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + H2O = a 2,3-saturated aldehyde + sn-glycerol 3-phosphocholine


name: PSMD14 cleaves K63-linked ubiquitin (Canis familiaris)


name: Loading of antigen peptide onto MHC class I molecule (Rattus norvegicus)


name: pyridoxine 5'-phosphate + O2 = pyridoxal 5'-phosphate + H2O2


name: p-S446-IRF5 dimer translocates to the nucleus (Canis familiaris)


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Rattus norvegicus)


name: 2 reduced [cytochrome P450] + NADP(+) + H(+) => 2 oxidized [cytochrome P450] + NADPH


name: L-leucine(in) + L-phenylalanine(out) <=> L-leucine(out) + L-phenylalanine(in)


name: (2R)-3-(3,4-dihydroxyphenyl)lactate + NAD(+) = 3-(3,4-dihydroxyphenyl)pyruvate + NADH + H(+)


name: inhibition of ATF6 signaling in response to endoplasmic reticulum stress


name: p-T-EIF2AK1:ferriheme dimer autophosphorylates (Homo sapiens)


name: Translocation of BIM to mitochondria (Homo sapiens)


name: DHNTP is dephosphorylated by PTPS to PTHP (Mus musculus)


name: gamma-L-glutamyl-[BtrI ACP] + H(+) <=> 4-aminobutanoyl-[BtrI ACP] + CO2


name: Transport of MHC I:Nef:AP-1:PACS-1 Complex (Homo sapiens)


name: Na+/H+ exchanger transport (at trans-golgi membrane) (Homo sapiens)


name: a 1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycerol 3-phosphocholine => a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: PIP3 recruits PDPK1 to the membrane (Bos taurus)


name: malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome (Sus scrofa)


name: polymyxin transmembrane transporter activity


name: Ca impermeable AMPA receptor ligand binding (Homo sapiens)


name: CBL-mediated ubiquitination of CIN85 (Bos taurus)


name: DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) (Drosophila melanogaster)


name: Intraphagosomal pH is lowered to 5 by V-ATPase (Rattus norvegicus)


name: PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Xenopus tropicalis)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Homo sapiens)


name: [DsrC protein]-disulfide + sulfite + H(+) => [DsrC protein]-S-sulfo-L-cysteine/L-cysteine


name: 2-hydroxyestrone + S-adenosyl-L-methionine = 2-hydroxy-3-methoxy-estrone + S-adenosyl-L-homocysteine + H(+)


name: DLST transfers glutaryl to CoA (Rattus norvegicus)


name: [DsbD protein]-dithiol + [thioredoxin]-disulfide => [DsbD protein]-disulfide + [thioredoxin]-dithiol


name: Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex (Homo sapiens)


name: 1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O => 1-tetradecanoyl-sn-glycero-3-phosphocholine + (9Z,12Z)-octadecadienoate + H(+)


name: NSF and SNAPs bind the cis-SNARE at the Golgi (Gallus gallus)


name: DHAP is converted to 1-acyl GO3P by GNPAT (Caenorhabditis elegans)


name: Autophosphorylation of KIT (Homo sapiens)


name: DICER1 cleaves tRNA Lys TTT 3 in tRNA:HIV RNA hybrid (Homo sapiens)


name: Cleavage of uracil by TDG glycosylase (Bos taurus)


name: p-S-TBK1 phosphorylates OPTN (Rattus norvegicus)


name: Recruitment of PAR-3:PAR-6:aPKC complex to tight junctions (Mus musculus)


name: DLD dimer dehydrogenates dihydrolipoyl (Rattus norvegicus)


name: 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP (Sus scrofa)


name: RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Gallus gallus)


name: Oxidative demethylation of 3-meC damaged DNA By ALKBH3 (Homo sapiens)


name: SOS binds Grb2 bound to pFAK:NCAM1 (Canis familiaris)


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus (Schizosaccharomyces pombe)


name: (2R)-3-phospho-glyceroyl phosphate + NADH + H(+) => D-glyceraldehyde 3-phosphate + phosphate + NAD(+)


name: PTPN22 dephosphorylates ZAP70 (Bos taurus)


name: alpha-maltose 1-phosphate + [(1->4)-alpha-D-glucosyl](n) => [(1->4)-alpha-D-glucosyl](n+2) + phosphate


name: N(6)-(5-O-phospho-D-ribulosyl)-L-lysyl-[protein] + H2O => N(6)-D-ribulosyl-L-lysyl-[protein] + phosphate


name: 3'-dephospho-CoA + a 5'-end phospho-ribonucleoside in mRNA + H(+) => a 5'-end CoA-ribonucleoside in mRNA + H2O


name: all-trans-antheraxanthin + L-dehydroascorbate + H2O => all-trans-violaxanthin + L-ascorbate


name: Integrin alpha7beta1 binds Laminin-211, 221, 411, 512, 521 (Homo sapiens)


name: (1R,2S)-ephedrine + NAD(+) = (S)-2-methylamino-1-phenylpropan-1-one + NADH + H(+)


name: (19E)-geissoschizine + NADPH + H(+) <=> (16R,19Z)-isositsirikine + NADP(+)


name: Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Gallus gallus)


name: POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA (Canis familiaris)


name: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O <=> 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate


name: 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+)


name: 12-hydroxyoctadecanoate + ATP + CoA => 12-hydroxyoctadecanoyl-CoA + AMP + diphosphate


name: WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Rattus norvegicus)


name: cyclic (2R)-2,3-bisphosphoglycerate + ADP + phosphate => (2R)-2,3-bisphosphoglycerate + ATP + H(+)


name: PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 (Canis familiaris)


name: (3R)-vestitone + NADP(+) <=> 2'-hydroxyformononetin + NADPH + 2 H(+)


name: Fgr may phosphorylate p38 MAPK (Rattus norvegicus)


name: 2-oxindole-3-acetate + succinyl-CoA => (2-oxoindol-3-yl)acetyl-CoA + succinate


name: guanidinoacetate + H2O => urea + glycine


name: An unknown protease degrades ACACA (Homo sapiens)


name: Activation of Ca2+ activated Potassium channels with small conductance (Bos taurus)


name: 2-deoxy-2,3-dehydro-N-acetylneuraminate + H2O <=> N-acetyl-alpha-neuraminate


name: BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose (Xenopus tropicalis)


name: N(6)-(2E)-butenoyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]


name: HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Drosophila melanogaster)


name: NPC exports GCK1 from nucleus (Canis familiaris)


name: cAMP dissociates PKA, promoting GLI processing (Sus scrofa)


name: Ceramide synthases transfer acyl-CoA onto sphingoid (Rattus norvegicus)


name: cyclic (2R)-2,3-bisphosphoglycerate + H2O => (2R)-2,3-bisphosphoglycerate + 2 H(+)


name: 2-dehydro-3-deoxy-D-gluconate + NAD(+) <=> 3-deoxy-D-glycero-2,5-hexodiulosonate + NADH + H(+)


name: prekallikrein + kininogen:C1q binding protein tetramer -> prekallikrein:kininogen:C1q binding protein tetramer (Gallus gallus)


name: CFTR transits to the plasma membrane (Caenorhabditis elegans)


name: PLK1 hyperphosphorylates Condensin II complex (Homo sapiens)


name: p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Drosophila melanogaster)


name: 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ (Caenorhabditis elegans)


name: Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome (Sus scrofa)


name: but-3-ynal + NAD(+) + H2O <=> 3-butynoate + NADH + 2 H(+)


name: ent-8alpha-hydroxylabd-13-en-15-yl diphosphate = ent-13-epi-manoyl oxide + diphosphate


name: beta-bisabolene + diphosphate => (2Z,6Z)-farnesyl diphosphate


name: sphinga-4E,14Z-dienine + octadecanoyl-CoA <=> N-octadecanoyl-sphinga-4E,14Z-dienine + CoA + H(+)


name: MHC class II antigen processing (Bos taurus)


name: alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Homo sapiens)


name: Oxidative damage to the AP site (Bos taurus)


name: a ganglioside Gal-(Fuc)-GA1 + UDP-N-acetyl-alpha-D-galactosamine => a ganglioside GalNAcGal-(Fuc)-GA1 + UDP + H(+)


name: [(1->4)-alpha-D-galacturonosyl methyl ester](n) + n H2O = [(1->4)-alpha-D-galacturonosyl](n) + n methanol + n H(+)


name: (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + H2O <=> (R)-glycerate + D-glucose


name: LTA4 is hydolysed to LTB4 by LTA4H (Mus musculus)


name: PC is converted to PS by PTDSS1 (Homo sapiens)


name: Coat Assembly (Schizosaccharomyces pombe)


name: L-leucine(out) + L-methionine(in) => L-leucine(in) + L-methionine(out)


name: 7,8-dihydroneopterin 3'-triphosphate + H2O <=> 7,8-dihydroneopterin 3'-phosphate + diphosphate + H(+)


name: CBL ubiquitinates FRS2 and FGFR2 (Homo sapiens)


name: DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG (Bos taurus)


name: N-(9Z-octadecenoyl)-L-tyrosine + H2O <=> L-tyrosine + (9Z)-octadecenoate


name: phloretate + NAD(+) <=> (E)-4-coumarate + NADH + H(+)


name: a flavonol + succinate + CO2 + H2O => a (2R,3R)-dihydroflavonol + 2-oxoglutarate + O2


name: platelet-derived growth factor alpha-receptor activity


name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Mus musculus)


name: hexan-1-ol + hexanoyl-CoA <=> hexyl hexanoate + CoA


name: Ubiquitinated Orc1 enters the cytosol (Drosophila melanogaster)


name: D-gluconate + alpha-D-glucose 1-phosphate => 4-O-beta-D-glucopyranosyl-D-gluconate + phosphate


name: PDE3A hydrolyses cAMP to AMP (Bos taurus)


name: an acyl phosphate + H2O => a carboxylate + phosphate + H(+)


name: Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Homo sapiens)


name: Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex (Drosophila melanogaster)


name: an N-terminal L-alpha-aminoacyl-[protein] + L-arginyl-tRNA(Arg) => an N-terminal L-arginyl-L-aminoacyl-[protein] + tRNA(Arg) + H(+)


name: (2E,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NADPH + H(+) => (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + NADP(+)


name: SHC1 phosphorylation by ERBB2 heterodimers (Mus musculus)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Plasmodium falciparum)


name: (8S)-8-amino-7-oxononanoate + S-adenosyl-L-methionine => S-adenosyl-4-methylsulfanyl-2-oxobutanoate + (7R,8S)-7,8-diammoniononanoate


name: EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA (Xenopus tropicalis)


name: 2-acyl LPG is acylated to PG by LPGAT (Danio rerio)


name: an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an N-acylsphing-14Z-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: D-galactose(out) + ATP + H2O => D-galactose(in) + ADP + phosphate + H(+)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 (Danio rerio)


name: MRN bound to shortened telomeres activates ATM (Mus musculus)


name: D-threo-isocitrate + NADP(+) => (S)-oxalosuccinate + NADPH + H(+)


name: succinyl-CoA + L-serine = O-succinyl-L-serine + CoA


name: p-S184,T180-CD274 binds to BTRC-SCF E3 ubiquitin ligase complex (Homo sapiens)


name: SLC2A1 tetramer transports Glc from cytosol to Golgi lumen (Dictyostelium discoideum)


name: SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Plasmodium falciparum)


name: 2 formaldehyde + H2O = methanol + formate + H(+)


name: dopamine + hexadecanoyl-CoA = N-hexadecanoyl-dopamine + CoA + H(+)


name: TTR:RBP:atROL binds to STRA6 receptor (Mus musculus)


name: intracellular calcium-activated potassium channel


name: p-Y694-STAT5A, p-STAT5B dimerizes (Bos taurus)


name: all-trans-zeaxanthin + O2 => (3R)-3-hydroxy-10'-apo-beta-carotenal + (3R)-hydroxy-beta-ionone


name: FOXA1 and GATA3 bind TFF genes (Homo sapiens)


name: taurocholate + L-alanine = L-alanocholate + taurine


name: CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Homo sapiens)


name: protein serine pyrophosphorylase activity


name: 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + O-phospho-L-seryl-[protein] = O-diphospho-L-seryl-[protein] + 1D-myo-inositol hexakisphosphate


name: CMP-5'-(3-aminopropyl)phosphonate + CO2 => CMP-5'-(3-amino-3-carboxypropyl)phosphonate + H(+)


name: CDO binds promyogenic cadherins (Sus scrofa)


name: HSP90 binds eNOS:Caveolin-1:CaM complex (Gallus gallus)


name: N(1)-acetylspermidine + H2O => spermidine + acetate


name: HS2ST1 trimer sulfates IdoA at C2 in heparan sulfate (Danio rerio)


name: sym-homospermidine + acetyl-CoA <=> N(1)-acetyl-sym-homospermidine + CoA + H(+)


name: NUDT16 hydrolyses dIDP to dIMP (Sus scrofa)


name: a 3-oxo-Delta(4)-steroid + A => a 3-oxo-Delta(1,4)-steroid + AH2


name: 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates (Bos taurus)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + 2 H2O => 3-beta-D-galactosyl-sn-glycerol + 2 a fatty acid + 2 H(+)


name: p-S26-ANXA2 binds integrin alpha5:beta1 at the plasma membrane (Drosophila melanogaster)


name: TRPC1 translocates calcium from the extracellular region to the cytosol (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Plasmodium falciparum)


name: OTUD3 deubiquitinates PTEN (Dictyostelium discoideum)


name: thyroid hormone transmembrane transporter activity


name: POLZ extends translesion synthesis (Schizosaccharomyces pombe)


name: Formation of the SET1A complex (Homo sapiens)


name: MAD2 associates with the Mad1 kinetochore complex (Sus scrofa)


name: Interaction of GRB2:SOS complex with p-SHC1 (Drosophila melanogaster)


name: a 2-acyl-sn-glycero-3-phospho-L-serine + H2O <=> a 2-acyl-sn-glycerol 3-phosphate + L-serine + H(+)


name: thiocyanate + S-adenosyl-L-methionine = methyl thiocyanate + S-adenosyl-L-homocysteine


name: HINT1, SIN3A and HDAC1 bind MITF-M at the BCL2 promoter (Mus musculus)


name: (2E)-geranyl diphosphate = alpha-thujene + diphosphate


name: PPP1R3C binds to glycogen:GYG1:GYS1 (Caenorhabditis elegans)


name: ME1 tetramer decarboxylates MAL to PYR (Caenorhabditis elegans)


name: tricetin + S-adenosyl-L-methionine = 3'-O-methyltricetin + S-adenosyl-L-homocysteine + H(+)


name: aphidicolan-16beta-ol + diphosphate => 9alpha-copalyl diphosphate + H2O


name: Gamma-secretase cleaves APP(672-770) to APP(672-711) and APP(672-713) (Homo sapiens)


name: PETA and CTP are condensed to CDP-ETA by PCY2 (Homo sapiens)


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> phomopsene + diphosphate


name: (2R)-3-phospho-glyceroyl phosphate + GDP => (2R)-3-phosphoglycerate + GTP


name: Benzene is hydroxylated to phenol (Caenorhabditis elegans)


name: stimulation of phospholipase A2 activity


name: a (2R)-2-hydroperoxy fatty acid + H(+) <=> a fatty aldehyde + CO2 + H2O


name: ISGylation of PKR (Drosophila melanogaster)


name: RUNX3 binds SMAD3 and SMAD4 (Canis familiaris)


name: UDP-alpha-D-galacturonate(out) + UMP(in) => UDP-alpha-D-galacturonate(in) + UMP(out)


name: SALMs 1-3 bind to PSD-95 family members (Mus musculus)


name: ITGA4:ITGB1 binds natalizumab (Danio rerio)


name: p-Y701-STAT1 dimer translocates from the cytosol to the nucleus (Drosophila melanogaster)


name: D-serine + A + H2O <=> 3-hydroxypyruvate + AH2 + NH4(+)


name: HDACs deacetylate p-STAT3 dimers (Sus scrofa)


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Drosophila melanogaster)


name: Formation of hydroxyallysine by LOX (Rattus norvegicus)


name: MLKL binds PDCD6IP and SDCBP (Mus musculus)


name: RHOD:GTP translocates to the endosome membrane (Gallus gallus)


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP(+) => 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H(+)


name: EGFR phosphorylates EPS15 (Mus musculus)


name: (R)-malyl-CoA + succinate => (R)-malate + succinyl-CoA


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Homo sapiens)


name: Dephosphorylation of inactive SRC by PTPB1 (Drosophila melanogaster)


name: 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine => 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate


name: proMMP9 binds TIMP1 (Drosophila melanogaster)


name: acetone + hydrogencarbonate + 2 ATP + 3 H2O = acetoacetate + 2 AMP + 4 phosphate + 4 H(+)


name: Formation of the Spliceosomal Pre-B complex (Homo sapiens)


name: HMG CoA => acetoacetic acid + acetyl CoA (Mus musculus)


name: (R)-5-phosphomevalonate + ATP <=> isopentenyl phosphate + ADP + phosphate + CO2


name: Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans (Xenopus tropicalis)


name: 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Dictyostelium discoideum)


name: Conversion of Glycerol to Glycerol-3-phosphate (Homo sapiens)


name: TRIP11:IFT20 dissociates (Caenorhabditis elegans)


name: gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6 (Gallus gallus)


name: Activation of linoleic acid to linoleoyl-CoA (Sus scrofa)


name: an alpha-D-GalNAc-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + H2O <=> an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + N-acetyl-D-galactosamine


name: alpha-D-galactose + ATP => alpha-D-galactose 1-phosphate + ADP + H(+)


name: (9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CoA => (9Z)-hexadecenoyl-CoA + sn-glycerol 3-phosphocholine


name: Receptor CXC1 binds to the ligands lymphotactin and cytokine SCM-1 beta (Mus musculus)


name: NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Gallus gallus)


name: diglucosyl diacylglycerol synthase activity


name: 5-aminopentanoate + 2-oxoglutarate = 5-oxopentanoate + L-glutamate


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + glycerol + H(+) => 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + H2O


name: ORC1 translocates to the nucleus (Xenopus tropicalis)


name: APP translocates from plasma membrane to endosome lumen (Homo sapiens)


name: CDH1 associates with CTNND1 (Gallus gallus)


name: a glycyl-glycyl-[protein] + H2O = N-terminal glycyl-[protein] + [protein]-C-terminal glycine


name: TRAPPC complexes exchange GTP for GDP on RAB1 (Mus musculus)


name: a 1-O-alkyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + CoA


name: a neolactoside nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose <=> a neolactoside III(3)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+)


name: MHC class II antigen processing (Rattus norvegicus)


name: Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Drosophila melanogaster)


name: 3-hydroxypropanoyl-CoA = acryloyl-CoA + H2O


name: Caspase-8 processing within TLR4 complex (Canis familiaris)


name: Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Homo sapiens)


name: Endocytosis of TLR4:LY96:LPS:CD14 (Bos taurus)


name: ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Canis familiaris)


name: Caspase-mediated cleavage of Etk (Drosophila melanogaster)


name: ESR1 binds to TFF1 gene promoter (Drosophila melanogaster)


name: L-methionyl(44)-[F-actin] + NADPH + O2 + H(+) <=> L-methionyl(44)-(R)-S-oxide-[F-actin] + NADP(+) + H2O


name: [L-4-(L-arginin-2-N-yl)aspartate](n+1) + ADP + phosphate + H(+) => [L-4-(L-arginin-2-N-yl)aspartate](n)-L-aspartate + L-arginine + ATP


name: Inactive G alpha (z) reassociates with G beta:gamma (Homo sapiens)


name: protein-N(PI)-phosphohistidine-galactosamine phosphotransferase system transporter activity


name: a neolactoside IV(4)-beta-GalNAc-IV(3)-alpha-NeuGc-nLc4Cer(d18:1(4E)) + UDP + H(+) => a neolactoside IV(3)-alpha-NeuGc-nLc4Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine


name: I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol (Bos taurus)


name: "Linked to the hydrolysis of diphosphate"


name: FGFR2c mutants bind an expanded range of ligands (Homo sapiens)


name: a menaquinol + 2 H(+)(out) => H2 + a menaquinone + 2 H(+)(in)


name: Recruitment of SOS to plasma membrane (Homo sapiens)


name: Basigin binds Matrix metalloproteinase-1 (Bos taurus)


name: episterol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 5-dehydroepisterol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: streptomycin + ATP <=> 3''-O-adenylylstreptomycin + diphosphate


name: [alpha-D-GalNAc-(1->4)]4-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP-alpha-D-glucose = [alpha-D-GalNAc-(1->4)]2-[beta-D-Glc-(1->3)]-[alpha-D-GalNAc-(1->4)]2-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP + H(+)


name: PRKN binds p-S-Ub:MOM proteins (Homo sapiens)


name: CLCN4/5/6 exchange Cl- for H+ (Danio rerio)


name: castasterone + reduced [NADPH--hemoprotein reductase] + O2 <=> brassinolide + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Expression of Acyl-CoA Desaturase (Stearoyl CoA Desaturase, SCD) (Homo sapiens)


name: FGR binds and phosphorylates LRP8 (Mus musculus)


name: 4-phenylbutan-2-amine + NAD(+) + H2O => 4-phenylbutan-2-one + NH4(+) + NADH + H(+)


name: Cholesterol is hydroxylated to 25-hydroxycholesterol (Caenorhabditis elegans)


name: 'de novo' pyridoxal 5'-phosphate biosynthetic process


name: 2 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + O2 => 2 tellimagrandin II + 2 H2O + 2 H(+)


name: tyramine + O2 + H2O => (4-hydroxyphenyl)acetaldehyde + H2O2 + NH4(+)


name: holo-[peptidyl-carrier protein] + glycine + ATP <=> glycyl-[peptidyl-carrier protein] + AMP + diphosphate


name: cyclohexanone + H2O2 + NH4(+) => cyclohexylamine + O2 + H2O


name: TST transfers sulfur from S2O3(2-) to HCN to form HSCN (Dictyostelium discoideum)


name: 6-amino-6-deoxyfutalosine + H2O = dehypoxanthine futalosine + adenine


name: Expression of globin genes under control of the beta globin control region (Homo sapiens)


name: USP13 deubiquitinates BECN1,USP10 (Homo sapiens)


name: Exocytosis of ficolin-rich granule membrane proteins (Dictyostelium discoideum)


name: RAN:GTP recruits nuclear envelope (NE) membranes (Drosophila melanogaster)


name: protein-DNA covalent cross-linking activity


name: RHOG GAPs stimulate RHOG GTPase activity (Sus scrofa)


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus (Bos taurus)


name: Formation of the MLL4 complex (Canis familiaris)


name: minus-end-directed microtubule motor activity


name: cAMP hydrolysis by Cam-PDE 1 (Gallus gallus)


name: Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Sus scrofa)


name: CMP-N-acetyl-9-O-acetyl-beta-neuraminate + CoA => CMP-N-acetyl-beta-neuraminate + acetyl-CoA


name: pseudotropine + NADP(+) => tropinone + NADPH + H(+)


name: acetylcholine receptor regulator activity


name: all-trans-4,4'-diapolycopen-4-al + A + H2O => all-trans-4,4'-diapolycopen-4-oate + AH2 + H(+)


name: 5alpha-androstane-3beta,17beta-diol + reduced [NADPH--hemoprotein reductase] + O2 = 5alpha-androstane-3beta,6alpha,17beta-triol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: octacosanoyl-CoA + malonyl-CoA + H(+) => 3-oxo-triacontanoyl-CoA + CO2 + CoA


name: CDC42 GAPs stimulate CDC42 GTPase activity (Bos taurus)


name: Movement of clathrin coated vesicles into early endosome (Mus musculus)


name: 1-octadecanoyl-sn-glycero-3-phosphocholine + H2O = octadecanoate + sn-glycerol 3-phosphocholine + H(+)


name: IGFBP4 binds IGF forming IGF:IGFBP4 (Homo sapiens)


name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Bos taurus)


name: thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Bos taurus)


name: (Z)-non-6-enal + NADPH + H(+) => (Z)-non-6-en-1-ol + NADP(+)


name: a 4-carboxy-3-alkylbut-(2E)-enoyl-[ACP] + H(+) => a 3-alkylbut-(2E)-enoyl-[ACP] + CO2


name: OTUD3 deubiquitinates PTEN (Caenorhabditis elegans)


name: MBD2 binds methylcytosine in chromatin (Sus scrofa)


name: STAT92E is phosphorylated by phosphorylated HOP (Drosophila melanogaster)


name: RCHY1 binds alanine-tailed nascent peptide and Ub:UBE2D2 (Xenopus tropicalis)


name: Interaction of SOS with GRB2 bound to FADK1 (Gallus gallus)


name: SEC31:SEC13 and v-SNARE recruitment (Sus scrofa)


name: N-acyl-1-deoxysphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => N-acyl-1-deoxysphing-14Z-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: L-2-amino-4-chloropent-4-enoate => L-propargylglycine + chloride + H(+)


name: 4alpha-carboxy-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O => 4alpha-formyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + H(+)


name: SOCS-1 and SOCS-3 binds to p-JAK2 (Sus scrofa)


name: an alpha-D-mannosyl-(1<->6)-1D-myo-inositol-1-phospho-N-(2-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) = an alpha-D-mannosyl-6-(1D-myo-inositol phospho)-(1<->6)-1D-myo-inositol-1-phospho-N-(2-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base + a 1,2-diacyl-sn-glycerol


name: RUNX1 binds the CLDN5 (Claudin-5) gene promoter (Homo sapiens)


name: taurine(in) + ADP + phosphate + H(+) => taurine(out) + ATP + H2O


name: neoechinulin A + dimethylallyl diphosphate <=> isoechinulin A + diphosphate


name: soyasapogenol B 3-O-beta-D-glucuronate + UDP-alpha-D-galactose = soyasaponin III + UDP + H(+)


name: "soyasapogenol B glucuronide galactosyltransferase"


name: Transhomodimerization of Nectins (Xenopus tropicalis)


name: PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal (Homo sapiens)


name: PGAM dimers isomerise 2PG to 3PG (Homo sapiens)


name: SYK is a substrate for JAK1 (Bos taurus)


name: DDO oxidizes D-Asp to OA (Dictyostelium discoideum)


name: 3-phosphonopyruvate + acetyl-CoA + H2O = (R)-2-(phosphonomethyl)malate + CoA + H(+)


name: alpha,alpha-trehalose + a ribonucleoside 5'-diphosphate + H(+) => an NDP-alpha-D-glucose + D-glucose


name: NEDD4 binds ERBB4jmAcyt1s80 dimer (Rattus norvegicus)


name: tRNA(Glu) + L-glutamate + ATP => L-glutamyl-tRNA(Gln) + AMP + diphosphate


name: Activated FGFR4 mutants phosphorylate PLCG1 (Homo sapiens)


name: 3-(2,3-dihydroxyphenyl)propanoate + O2 <=> (2Z,4E)-2-hydroxy-6-oxonona-2,4-dienedioate + H(+)


name: CaMKK binds activated calmodulin in the nucleus (Homo sapiens)


name: Neurotensin receptors can bind neurotensins (Mus musculus)


name: FUK phosphorylates beta-Fuc to Fuc1P (Mus musculus)


name: PDSS1,2 ligates FPP to IPPP (Plasmodium falciparum)


name: an N-(1-deoxy-beta-D-fructopyranos-1-yl)amine + O2 + H2O <=> an aliphatic amine + 2-dehydro-D-glucose + H2O2


name: glycerol dibiphytanyl glycerol tetraether glycerophospholipid + 4 5'-deoxyadenosine + 4 L-methionine + 2 A + 4 H(+) => 2 archaetidylglycerol + 2 AH2 + 4 S-adenosyl-L-methionine


name: 1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate


name: 1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine + 1,2-diheptanoyl-sn-glycero-3-phosphocholine <=> 1-heptanoyl-2-hexanoyl-sn-glycero-3-phosphoethanolamine + 1-hexanoyl-2-heptanoyl-sn-glycero-3-phosphocholine


name: Increased Spinal Cord Nerve Growth Factor Activity


name: chenodeoxycholate + UDP-alpha-D-glucuronate = chenodeoxycholoyl-24-O-(beta-D-glucuronate) + UDP


name: AFG3L2 binds mitochondrial matrix proteins (Rattus norvegicus)


name: N(2)-(4-aminobutanoyl)-L-lysine + H2O <=> 4-aminobutanoate + L-lysine


name: TFAP2C homodimer binds MYC and KDM5B (Mus musculus)


name: 2 L-citrulline + 2 nitric oxide + 3 NAD(+) + 4 H2O => 2 L-arginine + 3 NADH + 4 O2 + H(+)


name: glycosphingolipid ceramide deacylase activity


name: L-glutamate + ATP + H(+) = L-glutamyl-5'-AMP + diphosphate


name: PNPLA6 hydrolyzes LysoPtdCho (Caenorhabditis elegans)


name: Activated TP receptor binds G-proten Gq (Homo sapiens)


name: (1S,4S)-dihydrocarvone + NADH + H(+) => (1S,2R,4S)-neodihydrocarveol + NAD(+)


name: (4Z,15Z)-bilirubin IXalpha + UDP-alpha-D-glucuronate = (4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside + UDP


name: Decreased Sensory-Somatic Nervous System Epinephrine Activity


name: a 1,2-diacyl-sn-glycerol + H2O <=> a 1-acyl-sn-glycerol + a fatty acid + H(+)


name: Cathepsin G hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) (Xenopus tropicalis)


name: cAMP dissociates PKA, promoting GLI processing (Saccharomyces cerevisiae)


name: RUNX1 binds the SOCS3 gene (Homo sapiens)


name: 1,2,3-trihydroxybenzene + O2 = (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + 2 H(+)


name: octadecanoate + ATP + H(+) => octadecanoyl-AMP + diphosphate


name: 3,5-di-O-caffeoyl quinate + L-quinate => 2 chlorogenate


name: Interaction of ABL with ROBO1:SLIT2 (Mus musculus)


name: PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin (Bos taurus)


name: acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ (Homo sapiens)


name: NCOA1 binds ESR1:estrogen:TGFA gene (Canis familiaris)


name: Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA (Canis familiaris)


name: rhaponticin + malonyl-CoA => 6-O-malonyl-rhaponticin + CoA


name: kojibiose + phosphate => beta-D-glucose 1-phosphate + D-glucose


name: Generation of CLIP from lip10 (Canis familiaris)


name: 1-octadecanoyl-2-hexanoyl-sn-glycero-3-phosphocholine + H2O => hexanoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: ubiquinone-8 + formate(out) + 2 H(+)(in) => ubiquinol-8 + CO2(out) + H(+)(out)


name: glycyl-L-glutamate(out) + 2 H(+)(out) => glycyl-L-glutamate(in) + 2 H(+)(in)


name: (d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Caenorhabditis elegans)


name: 1,2,3-trioctanoylglycerol + H2O => dioctanoylglycerol + octanoate + H(+)


name: G protein-coupled adenosine receptor activity


name: SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Plasmodium falciparum)


name: 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Drosophila melanogaster)


name: a 1-acylglycerone 3-phosphate + NADPH + H(+) = a 1-acyl-sn-glycero-3-phosphate + NADP(+)


name: sabinene hydrate + diphosphate => (2E)-geranyl diphosphate + H2O


name: (E)-sinapaldehyde + NADP(+) + CoA <=> (E)-sinapoyl-CoA + NADPH + H(+)


name: ZnT8 transports zinc into the Golgi apparatus (Caenorhabditis elegans)


name: Aquaporins passively transport water into cells (Homo sapiens)


name: TNF-alpha inhibitors bind to soluble TNF trimer (Sus scrofa)


name: SALM2 associate with AMPA and NMDA receptors (Danio rerio)


name: AP1G2 binds HGS and CHMP2A (Drosophila melanogaster)


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Caenorhabditis elegans)


name: MAPK4,6 translocate to the cytoplasm (Homo sapiens)


name: Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex (Rattus norvegicus)


name: PE is hydrolyzed to 1-acyl LPE by PLA2[3] (Sus scrofa)


name: sn-glycerol 3-phosphate + octadecanoyl-CoA => 1-octadecanoyl-sn-glycero-3-phosphate + CoA


name: Hydrolysis of GTP and dissociation of 28S and 39S subunits (Caenorhabditis elegans)


name: 24-methylidenelophenol + 6 Fe(II)-[cytochrome b5] + 3 O2 + 5 H(+) <=> 4alpha-carboxy-ergosta-7,24(24(1))-dien-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: K63polyUb-cIAP1,2 ubiquitinates TRAF3 (Canis familiaris)


name: BACH1 binds MAFK (Drosophila melanogaster)


name: (2E,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + NADPH + H(+) => (15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + NADP(+)


name: SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Mus musculus)


name: FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: NEDD4L binds phosphorylated linker region of SMAD2/3 (Sus scrofa)


name: FGFR1c binds to Klotho-bound FGF23 (Danio rerio)


name: CD274 N-linked glycosylation in ER (Sus scrofa)


name: MBTPS1 (S1P) cleaves ATF6B (ATF6-beta) (Mus musculus)


name: L-alanyl-L-threonine(out) + ATP + H2O = L-alanyl-L-threonine(in) + ADP + phosphate + H(+)


name: PRDX5 reduces peroxynitrite to nitrite using TXN (Homo sapiens)


name: AMP(out) + NAD(+)(in) => AMP(in) + NAD(+)(out)


name: PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Drosophila melanogaster)


name: D-allose 6-phosphate = D-allulose 6-phosphate


name: NICD3 traffics to the nucleus (Homo sapiens)


name: 1,2-didecanoylglycerol + H2O <=> decanoylglycerol + decanoate + H(+)


name: (2S)-2-hydroxy-2-(2-methoxyphenyl)acetonitrile => 2-methoxybenzaldehyde + hydrogen cyanide


name: Increased Muscular System Endorphin Activity


name: butan-1-ol + NADP(+) = butanal + NADPH + H(+)


name: an alditol + NAD(+) => an aldose + NADH + H(+)


name: The RNA exosome in RNA exosome:NEXT:ZC3H18:CBCA:m7GpppN-RNA hydrolyzes RNA (Sus scrofa)


name: 9-cis-10'-apo-beta-carotenal + 2 O2 <=> (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal + (11R)-carlactone


name: L-tryptophan + O2 + H(+) = 3-indoleglycolaldehyde + NH4(+) + CO2


name: Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex (Homo sapiens)


name: (2E)-geraniol + NAD(+) = (2E)-geranial + NADH + H(+)


name: GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 2 phosphate + 3 H(+)


name: preaustinoid A1 + 2-oxoglutarate + O2 => berkeleyone B + succinate + CO2 + H2O


name: Cargo-carrying vesicles bud from the TGN (Sus scrofa)


name: a 1-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1-acyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycerol


name: SARS-CoV-2 nsp3 deISGylates ISGylated IFIH1 (Homo sapiens)


name: negative regulation of apolipoprotein binding


name: alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose <=> beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + UDP + H(+)


name: AMPK phosphorylates Raptor in the mTORC1 complex (Dictyostelium discoideum)


name: RNA Polymerase II Promoter Opening: First Transition (Bos taurus)


name: XPO1-dependent export of p-S69,S73 MITF-M (Rattus norvegicus)


name: anthranilate + L-phenylalanine + S-adenosyl-L-methionine + 2 ATP = cyclopeptine + 2 AMP + S-adenosyl-L-homocysteine + 2 diphosphate + 2 H(+)


name: Myosin phosphatase dephosphorylates PLK1 (Drosophila melanogaster)


name: 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 1-O-methyl-(8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatrienoate


name: (R)-reticuline + S-adenosyl-L-methionine <=> (R)-tembetarine + S-adenosyl-L-homocysteine + H(+)


name: IL37(?-218) translocates from the cytosol to the nucleus (Homo sapiens)


name: Formation of the CE:GMP intermediate complex (Dictyostelium discoideum)


name: Nitric oxide diffuses into the phagosome (Homo sapiens)


name: 2-hydroxyhexacosanoyl-CoA + sphinganine = N-(2-hydroxyhexacosanoyl)-sphinganine + CoA + H(+)


name: guanosine(1516) in 16S rRNA + S-adenosyl-L-methionine => N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine + H(+)


name: SENP1,2,5 proteolytically process SUMO1 (Mus musculus)


name: IMP + L-aspartate + GTP <=> N(6)-(1,2-dicarboxyethyl)-AMP + GDP + phosphate + 2 H(+)


name: 3,4-dinitrotoluene + NADH + O2 => 4-methyl-6-nitrocatechol + nitrite + NAD(+)


name: RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Schizosaccharomyces pombe)


name: 3-oxo-dotriacontanoyl-CoA + CO2 + CoA => triacontanoyl-CoA + malonyl-CoA + H(+)


name: 2 GTP + H(+) => P(1),P(4)-bis(5'-guanosyl) tetraphosphate + diphosphate


name: Crk's SH3 domain engages C3G (Homo sapiens)


name: 3-(4-hydroxyphenyl)pyruvate + dimethylallyl diphosphate = 3-dimethylallyl-4-hydroxyphenylpyruvate + diphosphate


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-alpha-D-glucose <=> alpha-D-glucosyl di-trans,octa-cis-undecaprenyl diphosphate + UMP


name: Active ARF recruits coatomer (Drosophila melanogaster)


name: ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) (Gallus gallus)


name: ursodeoxycholate + reduced [NADPH--hemoprotein reductase] + O2 = beta-muricholate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: STAB1 (FEEL-1) binds ligands (Rattus norvegicus)


name: (2R,3S)-3-isopropylmalate => 2-isopropylmaleate + H2O


name: sophoraflavanone B + reduced [NADPH--hemoprotein reductase] + O2 <=> leachianone G + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: USP4 deubiquitinate TRAF2,TRAF6 (Sus scrofa)


name: diacetylchitobiose-6'-phosphate + H2O = N'-monoacetylchitobiose-6'-phosphate + acetate


name: 2 sulochrin + O2 + 2 H(+) = 2 (2S)-bisdechlorogeodin + 2 H2O


name: MMP14 (MT1-MMP) binds TIMP2 (Danio rerio)


name: itaconate + succinyl-CoA => itaconyl-CoA + succinate


name: L-lysine + NADP(+) <=> L-1-piperideine-6-carboxylate + NH4(+) + NADPH + 2 H(+)


name: MDM2 ubiquitinates DYRK2 (Gallus gallus)


name: RP2:ARL3:GDP:UNC119B dissociates (Danio rerio)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Rattus norvegicus)


name: a cytidine in RNA + acetyl-CoA + ATP + H2O <=> an N(4)-acetylcytidine in RNA + ADP + phosphate + CoA + H(+)


name: dialurate + 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + H(+) => FMNH2 + O2


name: CDP-DAG is converted to PI by CDIPT (Dictyostelium discoideum)


name: HRH2 binds hist (Caenorhabditis elegans)


name: anditomin + succinate + CO2 + H2O => andilesin C + 2-oxoglutarate + O2


name: SEMA4D interacts with Plexin-B1:Met (Sus scrofa)


name: gamma-L-glutamylputrescine + O2 + H2O => 4-(gamma-L-glutamylamino)butanal + H2O2 + NH4(+)


name: GSDMD (1-275) binds bacterial cardiolipin (Gallus gallus)


name: hydrogencarbonate + acetyl-CoA + ATP <=> malonyl-CoA + ADP + phosphate + H(+)


name: 2-(prostaglandin G2)-sn-glycero-3-phosphoethanolamine => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 2 O2


name: SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- (Caenorhabditis elegans)


name: biotin + L-lysyl-[protein] + ATP <=> N(6)-biotinyl-L-lysyl-[protein] + AMP + diphosphate + H(+)


name: hexadecane-1,16-diol + O2 = hydroxyhexadecanal + H2O2


name: Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin (Drosophila melanogaster)


name: (11Z,14Z)-eicosadienoate + O2 = (15S)-hydroperoxy-(11Z,13E)-eicosadienoate


name: The NEXT complex binds ZC3H4:WDR82:CBCA:m7GpppN-RNA (Caenorhabditis elegans)


name: Ub,pS335,S338,T NFE2L2 is degraded (Sus scrofa)


name: diglucosyl-enterobactin + H2O => N-(2,3-dihydroxybenzoyl)-L-seryl-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2 + H(+)


name: p130Cas and C3G bind PDGFR bound Crk (Homo sapiens)


name: (3S)-citramalate + succinyl-CoA => (3S)-citramalyl-CoA + succinate


name: 3-oxo-(13Z,16Z,19Z)-docosatrienoyl-CoA + CO2 + CoA => (11Z,14Z,17Z)-eicosatrienoyl-CoA + malonyl-CoA + H(+)


name: an S-substituted L-cysteine + H2O <=> a thiol + pyruvate + NH4(+)


name: ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) (Xenopus tropicalis)


name: HINT1, SIN3A and HDAC1 bind MITF-M at the BCL2 promoter (Homo sapiens)


name: ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene (Homo sapiens)


name: Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Drosophila melanogaster)


name: Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)


name: 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Drosophila melanogaster)


name: (9Z)-octadecenoate(out) + ATP(in) + CoA(in) + H(+)(out) => (9Z)-octadecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: 2 flaviolin + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + H(+) = 3,8'-biflaviolin + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O


name: GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Caenorhabditis elegans)


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + 2 glutathione = (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + glutathione disulfide + H2O


name: a 1,2-diacylglycerol + H2O = a monoacylglycerol + a fatty acid + H(+)


name: 5-carboxymethoxyuridine(34) in tRNA + S-adenosyl-L-methionine = 5-methoxycarbonylmethoxyuridine(34) in tRNA + S-adenosyl-L-homocysteine


name: 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate 9-phosphate + H2O = 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate + phosphate


name: PPTN11 dephosphorylates SPRY2 (Mus musculus)


name: GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol (Homo sapiens)


name: IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Xenopus tropicalis)


name: p-S407,Y641-STAT6 is dimerized (Dictyostelium discoideum)


name: Receptor CCR7 binds CCL19 and 21 ligands (Canis familiaris)


name: RPA binds to the Flap (Schizosaccharomyces pombe)


name: 1-(9Z-octadecenoyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate


name: 4-coumaroyl-CoA + malonyl-CoA + H(+) => (4-coumaroyl)acetyl-CoA + CO2 + CoA


name: SUMOylation of TDG with SUMO1 (Schizosaccharomyces pombe)


name: (S)-2-hydroxyglutarate(in) + 3 Na(+)(in) => (S)-2-hydroxyglutarate(out) + 3 Na(+)(out)


name: HLCS biotinylates ACACA:Mn2+ (Homo sapiens)


name: Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Canis familiaris)


name: Release of SMAC (DIABLO) from mitochondria (Mus musculus)


name: positive regulation of lipoprotein lipase activity


name: Activation of Ca2+ activated Potassium channels with large conductance (Homo sapiens)


name: undecanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) => trans-2-undecenoyl-CoA + reduced [electron-transfer flavoprotein]


name: SLC25A32 transports THF from mitochondrial matrix to cytosol (Xenopus tropicalis)


name: glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate (Rattus norvegicus)


name: creatinine(in) + H(+)(out) <=> creatinine(out) + H(+)(in)


name: PRLR binds SCF beta-TrCP complex (Rattus norvegicus)


name: 11cROL translocates from Muller cells to cone photoreceptor cells (Sus scrofa)


name: 3,4-dihydroxybenzoate + NADPH + O2 + 2 H(+) = benzene-1,2,4-triol + CO2 + NADP(+) + H2O


name: RHAG transports CO2 from extracellular region to cytosol (Rattus norvegicus)


name: didehydrocampesine A + 2 H2O + H(+) => L-tryptophanal + L-valinal


name: Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Rattus norvegicus)


name: pyridoxal 5'-phosphate + H2O <=> pyridoxal + phosphate


name: Translocation of active Cdc25C to the nucleus (Mus musculus)


name: CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADP(+) + H2O = CDP-4-dehydro-6-deoxy-alpha-D-glucose + NADPH + H(+)


name: 4-hydroxy-6-(pyridin-3-yl)-2H-pyran-2-one + (2E,6E)-farnesyl diphosphate <=> 4-hydroxy-3-[(2E,6E)-farnesyl]-6-(pyridin-3-yl)-2H-pyran-2-one + diphosphate


name: NQO1 interaction with ODC (Rattus norvegicus)


name: Auto-ubiquitination of TRAF3 (Gallus gallus)


name: (3R)-3-hydroxydodecanoyl-CoA + NAD(+) <=> 3-oxododecanoyl-CoA + NADH + H(+)


name: 4-methylumbelliferone beta-D-glucuronate(out) + ADP + phosphate + H(+) => 4-methylumbelliferone beta-D-glucuronate(in) + ATP + H2O


name: 2-hydroxy-17beta-estradiol + UDP-alpha-D-glucuronate => 2-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronate) + UDP + H(+)


name: misfolded CFTR is degraded by the 26S proteasome (Mus musculus)


name: a 2'-deoxyguanosine in DNA + methylglyoxal <=> an N(2)-(1-hydroxy-2-oxopropyl)-2'-deoxyguanosine in DNA


name: homoserine transmembrane transporter activity


name: The Interleukin 1 receptor complex binds Tollip (Canis familiaris)


name: PHGDH tetramer dehydrogenates 3PG (Xenopus tropicalis)


name: N-terminal L-glutamyl-[protein] + N-acetyl-L-methionine => N-terminal N(alpha)-acetyl-L-methionyl-L-glutamyl-[protein] + H2O


name: estrone + reduced [NADPH--hemoprotein reductase] + O2 <=> 6alpha-hydroxyestrone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: MYSM1 deubiquitinates Histone H2A (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + UDP + H(+)


name: Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Canis familiaris)


name: (7S)-O-acetylsalutaridinol = thebaine + acetate + H(+)


name: Unknown kinase phosphorylates CLEC1B dimer:PDPN (Homo sapiens)


name: asperterpenoid A + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = asperterpenoid B + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 3 H(+)


name: DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs (Rattus norvegicus)


name: Inactive G alpha (i) reassociates with G beta:gamma (Bos taurus)


name: SPHK1 phosphorylates sphingoid (Saccharomyces cerevisiae)


name: (7Z,10Z,13Z)-hexadecatrienoyl-CoA + 1,2-dihexanoylglycerol = 1,2-dihexanoyl-3-(7Z,10Z,13Z-hexadecatrienoyl)-glycerol + CoA


name: 5-hydroxymethyl-dUMP in DNA + ATP = 5-phosphomethyl-dUMP in DNA + ADP + H(+)


name: aminoacyl-tRNA synthetase auxiliary protein activity


name: positive regulation of tatiopterin biosynthetic process


name: ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Homo sapiens)


name: DDHD1,2 hydrolyse PA (Xenopus tropicalis)


name: negative regulation of androgen receptor activity


name: a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine + H(+)


name: (S)-2,3,4,5-tetrahydrodipicolinate + NAD(+) + H2O => (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NADH + H(+)


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + hydrogencarbonate + ATP => 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + phosphate + 2 H(+)


name: AKR1B1 reduces Glc to D-sorbitol (Drosophila melanogaster)


name: low affinity sodium:dicarboxylate cotransporter activity


name: ADORA2B:Ade-Rib binds heterometric G-protein Gs (Homo sapiens)


name: gibberellin A12 + succinate + CO2 + H(+) => gibberellin A12 aldehyde + 2-oxoglutarate + O2


name: BTRC binds p-S344, 347 NFE2L2 (Canis familiaris)


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Caenorhabditis elegans)


name: Degradation of multiubiquitinated Cdh1 (Sus scrofa)


name: beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + GDP-alpha-D-mannose <=> beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: yersinopine + NADP(+) + H2O => (2S)-2-amino-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + pyruvate + NADPH + H(+)


name: N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 2-oxoglutarate + 2 O2 = L-lysyl(36)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2


name: 3-oxo-(11Z)-eicosenoyl-CoA + CO2 + CoA => (9Z)-octadecenoyl-CoA + malonyl-CoA + H(+)


name: ERBB4 forms heterodimers with ERBB3 (Danio rerio)


name: L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+) => tRNA(Phe) + L-phenylalanine + ATP


name: inhibition of nuclear mRNA catabolic process, deadenylation-dependent decay


name: PSMD5 and PSMD2 bind PSMC2:PSMC1 (Bos taurus)


name: 4alpha-methyl-5alpha-cholest-7-en-3-one + NADPH + H(+) => 4alpha-methyl-5alpha-cholest-7-en-3beta-ol + NADP(+)


name: 1,2,3-tri-(10Z)-heptadecenoylglycerol + 9-hydroxy-octadecanoate => 2,3-di-(10Z-heptadecenoyl)-sn-glycerol + 9-(10Z-heptadecenoyloxy)-octadecanoate


name: carnosine(out) + n H(+)(out) <=> carnosine(in) + n H(+)(in)


name: GTSE1 translocates to the nucleus (Gallus gallus)


name: Translocation of tetracosapentaenoyl-CoA to peroxisomes (Canis familiaris)


name: N(tele)-(N(7)-methylguanosine 5'-phospho)-L-histidyl-[protein] + a 5'-end diphospho-(purine-ribonucleoside) in mRNA + H(+) => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + L-histidyl-[protein]


name: 3-D-glucuronosyl-N(2),6-disulfo-beta-D-glucosamine + H2O = N(2),6-disulfo-D-glucosamine + D-glucuronate


name: CYP1A2 S-demethylates 6MMP (Danio rerio)


name: 8-methylthiopropyl glucosinolate S-oxygenase activity


name: daidzein 7-O-beta-D-glucoside + H2O = daidzein + beta-D-glucose + H(+)


name: Oxidative damage to the AP site (Drosophila melanogaster)


name: RAB9 GEFs exchange GTP for GDP on RAB9 (Mus musculus)


name: [glutaredoxin]-dithiol + arsenate + glutathione + H(+) <=> glutathionyl-S-S-[glutaredoxin] + arsenite + H2O


name: GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) (Canis familiaris)


name: 11-cis-retinol + hexadecanoyl-CoA <=> 11-cis-retinyl hexadecanoate + CoA


name: PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Rattus norvegicus)


name: maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) (Homo sapiens)


name: mTORC1 phosphorylates AKT1S1 (Xenopus tropicalis)


name: Translocation of ERBB4s80 to the nucleus (Canis familiaris)


name: N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B1) + H2O => N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2,3) + beta-D-mannose


name: 16S rRNA (guanine(1516)-N(2))-methyltransferase activity


name: 3-oxochol-4-en-22-oyl-CoA + acetyl-CoA <=> 3,22-dioxochol-4-en-24-oyl-CoA + CoA


name: DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) (Dictyostelium discoideum)


name: aspulvinone E + O2 => (2Z)-2-[(3,4-dioxocyclohexa-1,5-dien-1-yl)methylidene]-4-(4-hydroxyphenyl)-5-oxo-2,5-dihydrofuran-3-olate + H2O


name: an L-alpha-amino acid(in) + L-kynurenine(out) <=> an L-alpha-amino acid(out) + L-kynurenine(in)


name: (R)-prunasin + H2O <=> mandelonitrile + D-glucose


name: HTRA2 binds NDUFA13 (GRIM-19) (Homo sapiens)


name: MYC gene expression is enhanced by E2F1, STAT3, and CEBPB and repressed by CEBPA (Homo sapiens)


name: GLUT1 tetramer binds 4xATP (Canis familiaris)


name: 2 naphthalene-1,2,4,8-tetrol + O2 = 2 3,5-dihydroxy-1,4-naphthoquinone + 2 H2O + 2 H(+)


name: Coumarin is 7-hydroxylated by CYP2A6 (Dictyostelium discoideum)


name: PI3K-containing complexes phosphorylate PIP2 to PIP3 (Bos taurus)


name: 1,2-dihexadecanoyl-sn-glycerol + a sphingomyelin => 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine


name: NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Bos taurus)


name: 2-hydroxyethylphosphonate + CTP = cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + diphosphate


name: a 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + CDP-ethanolamine <=> a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: Active calmodulin binds CAMK2 (Rattus norvegicus)


name: fluoroacetyl-CoA + H2O <=> fluoroacetate + CoA + H(+)


name: HLCS biotinylates 6x(PCCA:PCCB) (Mus musculus)


name: PTK6 phosphorylates ARHGAP35 (Sus scrofa)


name: SUMOylation of TFAP2C with SUMO1 (Caenorhabditis elegans)


name: ADBRK1,2 phosphorylate AVPR2 (Homo sapiens)


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Rattus norvegicus)


name: 2xLTBR binds LTBR:lymphotoxin,TNFSF14 trimer (Sus scrofa)


name: 3beta-hydroxy-chol-5-ene-24-oyl-CoA + A = 3beta-hydroxy-chol-5,22-dien-24-oyl-CoA + AH2


name: Association of procollagen type XIX (Homo sapiens)


name: Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Mus musculus)


name: SFTPD binds with itself to form SFTPD 12mer (Plasmodium falciparum)


name: p-T,Y MAPK dimers translocate to nucleus (Homo sapiens)


name: p130 (RBL2) associates with MuvB to form DREAM complex (Caenorhabditis elegans)


name: N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-glucose = beta-D-glucosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + UDP + H(+)


name: MFSD2A transports LPC from extracellular region to plasma membrane (Bos taurus)


name: syringetin + S-adenosyl-L-homocysteine + H(+) => laricitrin + S-adenosyl-L-methionine


name: Interaction of beta-2-microglobulin (B2M) chain with  class I HC (Bos taurus)


name: cIAP1,2:TRAF2:TRAF3:NIK complex binds TNFR2 trimer (Bos taurus)


name: ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) (Drosophila melanogaster)


name: chaperone cofactor-dependent protein refolding


name: The acetyl group from acetyl-CoA is transferred to NAT1 (Bos taurus)


name: RAS proteins are depalmitoylated (Canis familiaris)


name: GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Canis familiaris)


name: PP2A dephosphorylates p-RHO to RHO (Sus scrofa)


name: VTN binds collagens I, IV and VI (Homo sapiens)


name: acetyl-CoA transmembrane transporter activity


name: [hyaluronan](n) = n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine + H2O


name: 13-(9Z-octadecenoyloxy)-octadecanoate + H2O = 13-hydroxy-octadecanoate + (9Z)-octadecenoate + H(+)


name: EPCAM binds itself to form homotypic cell adhesion (Sus scrofa)


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Danio rerio)


name: TFAP2A:TFAP2B binds the GBX2 gene (Homo sapiens)


name: PI3P is dephosphorylated to PI by MTMR2:SBF1 (Drosophila melanogaster)


name: HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Bos taurus)


name: BCDX2 complex stabilizes RAD51 filament (Sus scrofa)


name: 4 monapinone E + O2 <=> 2 dinapinone E + 2 H2O


name: 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Mus musculus)


name: L-cysteinyl-[SCAN] + S-nitroso-L-cysteinyl-[protein] => S-nitroso-L-cysteinyl-[SCAN] + L-cysteinyl-[protein]