name: CMP-N-acetyl-beta-neuraminate(out) + AMP(in) => CMP-N-acetyl-beta-neuraminate(in) + AMP(out)


name: pentanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) => (2E)-pentenoyl-CoA + reduced [electron-transfer flavoprotein]


name: HMGB1 binds LTP (Saccharomyces cerevisiae)


name: Exocytosis of azurophil granule lumen proteins (Bos taurus)


name: a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + a 1-O-alkyl-sn-glycero-3-phosphocholine => a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine


name: 4 monapinone E + O2 = 2 dinapinone E + 2 H2O


name: LPS binding to CD14 co-receptor (Gallus gallus)


name: Phosphorylation of pPTK2 by SRC (Gallus gallus)


name: TFIIS-mediated recovery of HIV-1 elongation from arrest (Homo sapiens)


name: [LarE protein]-L-cysteine + pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide + ATP <=> pyridinium-3,5-bisthiocarboxylate mononucleotide + [LarE protein]-dehydroalanine + AMP + diphosphate + H(+)


name: USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN (Homo sapiens)


name: a plastoquinone + 15-cis-phytoene = 15,9'-di-cis-phytofluene + a plastoquinol


name: all-trans-retinal + reduced [NADPH--hemoprotein reductase] + O2 => all-trans-retinoate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)


name: tetradecanoyl-[ACP] + L-lysyl-[protein] => N(6)-tetradecanoyl-L-lysyl-[protein] + holo-[ACP] + H(+)


name: a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate => an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP + H(+)


name: NR1H2,3 binds the ARL4C gene (Homo sapiens)


name: Activation of Ca2+ activated Potassium channels with  Intermediate conductance (Rattus norvegicus)


name: 6-deoxotyphasterol + reduced [NADPH--hemoprotein reductase] + O2 = 6alpha-hydroxytyphasterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP (Homo sapiens)


name: 2',3'-cGAMP + H2O => 5'-O-phosphonoguanyl-(2'->5')-adenosine + H(+)


name: The phagophore extends from the PIP3-enriched structure (Saccharomyces cerevisiae)


name: 9,9'-di-cis-zeta-carotene + a quinone <=> 7,9,9'-tri-cis-neurosporene + a quinol


name: TNKS and TNKS2 PARylate PTEN (Canis familiaris)


name: proton-dependent oligopeptide secondary active transmembrane transporter activity


name: a 1-O-alkyl-2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + 3'-phosphoadenylyl sulfate = a 1-O-alkyl-2-acyl-3-(beta-D-3-sulfogalactosyl)-sn-glycerol + adenosine 3',5'-bisphosphate + H(+)


name: CFTR transports Cl- from cytosol to extracellular region (Homo sapiens)


name: IFNG dimer binds IFNG inhibitors (Canis familiaris)


name: Dissociation of  transcript with 5'-GMP from GT (Schizosaccharomyces pombe)


name: AdoSeMet is converted to AdeSeHCys by MetTrans(1) (Homo sapiens)


name: a beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose => an alpha-D-Man-(1->6)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)


name: Galactosylation of Pre-NOTCH (Homo sapiens)


name: SHANK proteins bind GKAPs (Homo sapiens)


name: PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Homo sapiens)


name: LCAT + discoidal HDL <=> LCAT:discoidal HDL complex (Rattus norvegicus)


name: corticotropin-releasing hormone receptor binding


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Caenorhabditis elegans)


name: Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin (Homo sapiens)


name: NADPH oxidase 2 (NOX2) complex binds RAC1 (Bos taurus)


name: DTOR is positively regulated by DRheb-GTP (Drosophila melanogaster)


name: Rheb in the MTORC1 complex hydrolyses GTP (Gallus gallus)


name: 6-deoxyerythronolide B + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) <=> erythronolide B + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: p-S26-ANXA2 binds integrin alpha5:beta1 at the plasma membrane (Homo sapiens)


name: 9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + NADPH + O2 + H(+) <=> methyl 2-[(3S)-9,10-dihydroxy-7-methoxy-1-oxo-1H,3H,4H-naphtho[2,3-c]pyran-3-yl]acetate + NADP(+) + H2O


name: MDBH (membrane-associated dopamine beta-monooxygenase)


name: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Dictyostelium discoideum)


name: a 2'-deoxyguanosine in DNA + NAD(+) = an N(2)-(ADP-L-ribosyl)-2'-deoxyguanosine in DNA + nicotinamide + H(+)


name: SPHK1 phosphorylates sphingoid (Dictyostelium discoideum)


name: GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol (Homo sapiens)


name: glyoxal + GTP = N(2)-(1-hydroxy-2-oxoethyl)-GTP


name: SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine (Bos taurus)


name: broad specificity oxidative DNA demethylase activity


name: L-methionyl(44)-[F-actin] + NADPH + O2 + H(+) => L-methionyl(44)-(R)-S-oxide-[F-actin] + NADP(+) + H2O


name: SeMet is converted to AdoSeMet by MAT (Rattus norvegicus)


name: NFE2 gene expression is stimulated by RUNX1:CBFB (Homo sapiens)


name: SORD oxidizes D-sorbitol to Fru (Rattus norvegicus)


name: orotidine 5'-phosphate + diphosphate => orotate + 5-phospho-alpha-D-ribose 1-diphosphate


name: (3R)-hydroxy-(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA = (2E,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + H2O


name: a D-alpha-amino acid => an L-alpha-amino acid


name: IkB is ubiquitinated and degraded (Danio rerio)


name: IL26:IL20RA:JAK1 binds IL10RB:TYK2 (Gallus gallus)


name: L-tyrosine + L-arginine = N-amidino-L-tyrosine + L-ornithine


name: 3-phenylpyruvate + H(+) => 2-phenylacetaldehyde + CO2


name: 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ (Sus scrofa)


name: prostaglandin G1 + AH2 <=> prostaglandin H1 + A + H2O


name: a globoside MSGG + CMP-N-acetyl-beta-neuraminate => a globoside DSGG + CMP + H(+)


name: a 1,N(2)-etheno-2'-deoxyguanosine in single-stranded DNA + 2-oxoglutarate + O2 + H2O <=> a 2'-deoxyguanosine in single-stranded DNA + glyoxal + succinate + CO2


name: beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-D-glucosamine + GDP + H(+) => beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine + GDP-beta-L-fucose


name: negative regulation of nonadec-1-ene biosynthetic process


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + formate + ATP => 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + ADP + phosphate


name: CBP and p300 binds NF-kB complex (Canis familiaris)


name: cAMP response element binding protein binding


name: cAMP response element binding protein binding activity


name: CYPs hydroxylate DHA to 14(R)-HDHA (Caenorhabditis elegans)


name: cholestanol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = (25R)-26-hydroxycholestanol + 2 oxidized [adrenodoxin] + H2O


name: B4GAT1:LARGE transfers initial GlcA to matriglycan chain (Homo sapiens)


name: CYP46A1 24-hydroxylates CHOL (Canis familiaris)


name: (3E)-3,4-didehydrorhodopin + AH2 => rhodopin + A


name: plastoquinone-9 + 15-cis-phytoene => 15,9'-di-cis-phytofluene + plastoquinol-9


name: 1'-carboxy-chondrochloren B + FAD + 2 H(+) <=> chondrochloren B + FADH2 + CO2


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Bos taurus)


name: a 3-(acyloxy)acyl derivative of bacterial toxin + H2O <=> a 3-hydroxyacyl derivative of bacterial toxin + a fatty acid + H(+)


name: L-methionyl-L-phenylalanyl-L-methionine(out) + H(+)(out) <=> L-methionyl-L-phenylalanyl-L-methionine(in) + H(+)(in)


name: oxalate + ATP + CoA = oxalyl-CoA + AMP + diphosphate


name: Interaction of Tie2 and Shp2 (Rattus norvegicus)


name: an N(5)-acyl-L-ornithine ester + H2O = an N(5)-acyl-L-ornithine + an alcohol + H(+)


name: epidermal growth factor receptor signaling pathway involved in heart process


name: STING binds TRIM32 or TRIM56  (Sus scrofa)


name: Abortive initiation after formation of the first phosphodiester bond (Saccharomyces cerevisiae)


name: SLC26A4 exports I- to follicular lumen (Drosophila melanogaster)


name: 1-tetradecanoyl-3-(9Z-octadecenoyl)-glycerol + CoA => 1-tetradecanoylglycerol + (9Z)-octadecenoyl-CoA


name: ARC binds DNM2 and SH3GL3 (Homo sapiens)


name: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides


name: PP2A dephosphorylates KSR1 (Homo sapiens)


name: L-glutamate(in) + 2 H(+)(in) = L-glutamate(out) + 2 H(+)(out)


name: SHC1 dissociates from integrin alphaIIb beta3 (Rattus norvegicus)


name: ATP hydrolysis by HSP90 (Rattus norvegicus)


name: Kinesin-3 is a dimer (Rattus norvegicus)


name: PRC2 trimethylates histone H3 at lysine-27 (Homo sapiens)


name: Cu(2+)(out) + L-ascorbate(in) <=> Cu(+)(out) + monodehydro-L-ascorbate radical(in) + H(+)


name: an acyl phosphate + H2O = a carboxylate + phosphate + H(+)


name: TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)


name: dermatan + n 3'-phosphoadenylyl sulfate => dermatan 4'-sulfate + n adenosine 3',5'-bisphosphate + n H(+)


name: (2E,6E)-farnesyl diphosphate => (+)-amorpha-4,11-diene + diphosphate


name: Gi activation by P2Y purinoceptor 12 (Sus scrofa)


name: SLCO1B1 transports T3,T4 from extracellular region to cytosol (Rattus norvegicus)


name: THOP1 cleaves oligopeptide fragment (8-16aa) (Sus scrofa)


name: 2,3-dihydroxybenzoate + H(+) = catechol + CO2


name: IRS1 recruits GRB2 to active LTK (Rattus norvegicus)


name: Transport of MHC heterotrimer to ER exit site (Danio rerio)


name: glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH (Mus musculus)


name: omega-hydroxy-beta-dihydromenaquinone-9 + 3'-phosphoadenylyl sulfate => omega-sulfo-beta-dihydromenaquinone-9 + adenosine 3',5'-bisphosphate + H(+)


name: CTLH E3 ligase ubiquitinates PKM-1 (Homo sapiens)


name: PDCL binds G-protein beta and TRiC/CCT (Rattus norvegicus)


name: inhibition of smoothened signaling pathway in ventral spinal cord patterning


name: PRKCZ autophosphorylates downstream of estrogen stimulation (Homo sapiens)


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Homo sapiens)


name: (2R)-2-hydroxy-4-(methylsulfanyl)butanoate + NADP(+) => 4-methylsulfanyl-2-oxobutanoate + NADPH + H(+)


name: p-S92,203-BRF1 binds 14-3-3 (Rattus norvegicus)


name: Formation of MSH2:MSH3 Complex (Schizosaccharomyces pombe)


name: propanoate(out) + dehydroepiandrosterone 3-sulfate(in) <=> propanoate(in) + dehydroepiandrosterone 3-sulfate(out)


name: Formation of 4Fe-4S cluster on ISCA1:ISCA2 (Sus scrofa)


name: GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Bos taurus)


name: Interaction of Tie2 with Ang1 (Xenopus tropicalis)


name: short-chain fatty acid transporter activity


name: SMDT1 assists in assembling MCU, MCUB, MICU1, MICU2 (or MICU3) yielding the MCU complex (Homo sapiens)


name: C3a receptor binds anaphylatoxin C3a (Bos taurus)


name: isovitexin + UDP-alpha-D-glucose <=> isovitexin 2''-O-beta-D-glucoside + UDP + H(+)


name: MYO9B inactivates RHOA (Rattus norvegicus)


name: CYP3A43 6b-hydroxylates TEST (Homo sapiens)


name: p-VAV family:PIP3 binds RAC1:GDP (Homo sapiens)


name: an N-hydroxyarylamine + acetyl-CoA <=> an N-acetoxyarylamine + CoA


name: L-homoseryl-tRNA(Lys) + H2O <=> tRNA(Lys) + L-homoserine + H(+)


name: Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Rattus norvegicus)


name: TBK1, IKBKE binds Met1-polyUb within the TNFR1 complex (Homo sapiens)


name: Hydrolysis of Ran:GTP to Ran:GDP (Homo sapiens)


name: tBID binds to inactive BAX protein (Bos taurus)


name: alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ (Rattus norvegicus)


name: L-glutamate gamma-semialdehyde dehydrogenase activity


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Rattus norvegicus)


name: TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Canis familiaris)


name: a ganglioside GD1b (d18:1(4E)) + H2O = a ganglioside GM1 (d18:1(4E)) + N-acetylneuraminate


name: activation of extrinsic apoptotic signaling pathway via death domain receptors


name: PGM2:Mg2+ isomerises R1P to R5P (Dictyostelium discoideum)


name: PG is hydrolyzed to 1-acyl LPG by PLA2[1] (Homo sapiens)


name: Arresten binds integrin alpha1beta1 (Sus scrofa)


name: protodeoxyviolaceinate + NADPH + O2 + H(+) => protoviolaceinate + NADP(+) + H2O


name: bilirubin uridine diphosphoglucuronyltransferase activity


name: Translocation of YAP1:ZO-2 (TJP2) to the nucleus (Mus musculus)


name: POLZ elongates POLI-incorporated dNMP (Homo sapiens)


name: CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Rattus norvegicus)


name: DNA polymerase alpha:primase binds at the origin (Plasmodium falciparum)


name: AMPK is dephosphorylated (Drosophila melanogaster)


name: Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) (Danio rerio)


name: ubiquinone-8 + NADH + H(+) <=> ubiquinol-8 + NAD(+)


name: UDP-alpha-D-apiose + apigenin 7-O-beta-D-glucoside <=> 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone + UDP + H(+)


name: Coagulation factor XI activated | Platelet poor plasma | Coagulation


name: (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + NADPH + H(+) <=> (3R)-hydroxy-(9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + NADP(+)


name: TBC1D3 associates with RAB5 (Caenorhabditis elegans)


name: ALDH1B1 tetramer oxidises CH3CHO to CH3COOH (Schizosaccharomyces pombe)


name: 3-chlorocatechol + O2 = (2E,4Z)-2-chloromuconate + 2 H(+)


name: (1R,4S)-1-hydroxylimonen-2-one + NADPH + O2 => (3S)-3-isopropenyl-6-oxoheptanoate + NADP(+) + H2O


name: holo-[peptidyl-carrier protein] + L-tryptophan + ATP => L-tryptophyl-[peptidyl-carrier protein] + AMP + diphosphate


name: RGS proteins bind GNB5 and CCT/TRiC (Gallus gallus)


name: TP53BP1 recruits DCLRE1C to ATM (Gallus gallus)


name: a 1,2-saturated fatty acid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a 2-hydroxy fatty acid + 2 Fe(III)-[cytochrome b5] + H2O


name: HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Xenopus tropicalis)


name: ARL2:GTP bind PDE6D on KRAS4B (Homo sapiens)


name: hexadecanoyl-[ACP] + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) => (6Z)-hexadecenoyl-[ACP] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O


name: Pellino ubiquitinates hp-IRAK1 (Mus musculus)


name: tetradecane + reduced [NADPH--hemoprotein reductase] + O2 => 7-tetradecanol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Sus scrofa)


name: cyathatriol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => cyathadiol + reduced [NADPH--hemoprotein reductase] + O2


name: 2 3-(7-chloroindol-3-yl)-2-iminopropanoate + H2O2 = 7-chloroindole-3-pyruvate imine dimer + 2 H2O


name: Phosphorylated LEPR Binds STAT5 (Homo sapiens)


name: acetyl-CoA biosynthetic process from pantothenate


name: 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA <=> vanillin + acetyl-CoA


name: AQP1 tetramer transports CO2 from extracellular region to cytosol (Gallus gallus)


name: malonate(in) + phosphate(out) + H(+)(out) => malonate(out) + phosphate(in) + H(+)(in)


name: SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol (Canis familiaris)


name: 4',7,8-trihydroxyflavone + S-adenosyl-L-methionine <=> 7,8-dihydroxy-4'-methoxyflavone + S-adenosyl-L-homocysteine + H(+)


name: 1-dodecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-dodecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: (3S)-3-[2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-4-methylidenecyclohexan-1-one + reduced [NADPH--hemoprotein reductase] + O2 <=> 5-dehydro-6-demethoxyfumagillol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: isoterpinolene + diphosphate => (2E)-geranyl diphosphate


name: raffinose transmembrane transporter activity


name: all-trans-retinyl hexadecanoate + H2O = all-trans-retinol + hexadecanoate + H(+)


name: PYGB b dimer:AMP complex => PGYB dimer, b form + 2 AMP (Homo sapiens)


name: Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)


name: 5'-deoxyadenosine + H2O + H(+) <=> 5'-deoxyinosine + NH4(+)


name: PGLYRP2 binds bacterial peptidoglycan (Mus musculus)


name: RPS6KA1-dependent phosphorylation of MITF-M (Mus musculus)


name: N(6)-methyladenosine(2030) in 23S rRNA + S-adenosyl-L-homocysteine + H(+) => adenosine(2030) in 23S rRNA + S-adenosyl-L-methionine


name: Displacement of MUTYH glycosylase by APEX1 at the AP site (Plasmodium falciparum)


name: CRLF1:IL27 translocates to the extracellular region (Canis familiaris)


name: 1-deoxy-11-oxopentalenate + NADPH + O2 + H(+) <=> pentalenolactone D + NADP(+) + H2O


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Danio rerio)


name: kanamycin A + ATP => kanamycin 3'-phosphate + ADP + H(+)


name: exophillate + UDP-alpha-D-galactose <=> phaeomoniecin D + UDP + H(+)


name: PTK6 phosphorylates ARHGAP35 (Bos taurus)


name: (2E)-octadecenoyl-[ACP] + NADPH + H(+) <=> octadecanoyl-[ACP] + NADP(+)


name: 3-hydroxy-2-methylpropanoyl-CoA + H2O <=> 3-hydroxy-2-methylpropanoate + CoA + H(+)


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Mus musculus)


name: Potassium voltage-gated channels close in reponse to PKA (Bos taurus)


name: (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate <=> (5S,6S)-epoxy-(18S)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O


name: (2E,6E,10E)-geranylgeranyl diphosphate => (+)-kolavenyl diphosphate


name: ZIP6 and ZIP14 mediate zinc influx into cells (Bos taurus)


name: 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + H2O = octadecanoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: 4-(phosphooxy)-L-threonine + ADP + H(+) => 4-hydroxy-L-threonine + ATP


name: 2-methylpropanoyl-CoA + malonyl-[ACP] + H(+) <=> 4-methyl-3-oxopentanoyl-[ACP] + CO2 + CoA


name: CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (Schizosaccharomyces pombe)


name: N(6)-(D-erythrulosyl)-L-lysyl-[protein] + ATP => N(6)-(3-O-phospho-D-erythrulosyl)-L-lysyl-[protein] + ADP + H(+)


name: 1-dodecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-dodecanoyl-sn-glycerol 3-phosphate + choline + H(+)


name: D-galactonate(in) + H(+)(in) => D-galactonate(out) + H(+)(out)


name: SPOP:CUL3:RBX1 binds to CD274 (Bos taurus)


name: CES1 trimer.CES2 hydrolyse COCN to BEG (Xenopus tropicalis)


name: Follistatin (FST) binds Activin (Homo sapiens)


name: diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP(+) = diethyl 2-methyl-3-oxosuccinate + NADPH + H(+)


name: Alpha1-Microglobulin binds heme (Homo sapiens)


name: SHP2 binds to the active receptor (Rattus norvegicus)


name: RHOT1 binds effectors at the mitochondrial outer membrane (Bos taurus)


name: TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) (Rattus norvegicus)


name: Internal Methylation of mRNA (Drosophila melanogaster)


name: Egress of internalized antigen into cytosol from early endosome (Homo sapiens)


name: Association of procollagen type XVII (Gallus gallus)


name: FECH binds Fe2+ to PRIN9 to form heme (Rattus norvegicus)


name: Phosphorylation of cPLA2 by ERK-2 (Xenopus tropicalis)


name: 3-methylbutan-2-one + NH4(+) + NADPH + H(+) => 3-methyl-2-aminobutane + NADP(+) + H2O


name: Transfer of SUMO1 from E1 to UBE2I (UBC9) (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate + H2O => (-)-longiborneol + diphosphate


name: EHMT1:EHMT2 dimethylates TP53 (Mus musculus)


name: (2E)-butenoyl-CoA + L-lysyl-[protein] <=> N(6)-(2E)-butenoyl-L-lysyl-[protein] + CoA + H(+)


name: activation of inositol-requiring transmembrane kinase/endonuclease signal transduction


name: GSTK1 dimer transfers GS from GSH to CDNB (Rattus norvegicus)


name: 14-3-3 proteins bind AKT-phosphorylated FOXO4 (Drosophila melanogaster)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O <=> hydropyrenol + diphosphate


name: KAT2B,EP300 acetylate FOXO3 under oxidative stress (Danio rerio)


name: p-S407-STAT6 is phosphorylated at Tyr641 (Mus musculus)


name: GDP + S-adenosyl-L-methionine => N(7)-methyl-GDP + S-adenosyl-L-homocysteine


name: SLC35A1 exchanges CMP-Neu5Ac for CMP (Canis familiaris)


name: (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Plasmodium falciparum)


name: Activation of linoleic acid to linoleoyl-CoA (Mus musculus)


name: MET gene transcription is stimulated by MECP2 (Homo sapiens)


name: 1D-myo-inositol 2,5-bisphosphate + phosphate => 1D-myo-inositol 2,4,5-triphosphate + H2O


name: Phosphorylated MOB1A proteins associate with LATS proteins (Xenopus tropicalis)


name: 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoate + H(+) => 5,7-dihydroxy-4-methylphthalide + H2O


name: USP48 cleaves polyubiquitin (Gallus gallus)


name: (23Z,26Z,29Z,32Z)-octatriacontatetraenoyl-CoA + NADP(+) => (2E,23Z,26Z,29Z,32Z)-octatriacontapentaenoyl-CoA + NADPH + H(+)


name: D-arabinose + NAD(+) => D-arabinono-1,5-lactone + NADH + H(+)


name: C-terminal L-cysteinyl-[HypE protein] + carbamoyl phosphate + ATP + H2O = C-terminal S-carboxamide-L-cysteinyl-[HypE protein] + AMP + phosphate + diphosphate + H(+)


name: 8-hydroxy-(11S,12S)-epoxy-(5Z,9E,14Z)-eicosatrienoate + H2O = (8,11R,12S)-trihydroxy-(5Z,9E,14Z)-eicosatrienoate


name: Dephosphorylation of Gab1 by SHP2 (Xenopus tropicalis)


name: phosphoenolpyruvate + GDP + CO2 => oxaloacetate + GTP


name: L-aspartate + NADP(+) <=> iminosuccinate + NADPH + H(+)


name: SUMOylation of NCOA2 with SUMO1 (Homo sapiens)


name: Formation of CSL-NICD coactivator complex (Homo sapiens)


name: a bacteriochlorophyllide d + S-adenosyl-L-methionine + H2O = a 7(1)-hydroxybacteriochlorophyllide d + 5'-deoxyadenosine + L-methionine + H(+)


name: GTP + ATP => pppA(2'-5')pG + diphosphate


name: RHOT2 binds effectors at the mitochondrial outer membrane (Homo sapiens)


name: (2E)-glutaconyl-CoA + H2O2 => glutaryl-CoA + O2


name: Activation of voltage gated Potassium channels (Bos taurus)


name: Auto ubiquitination of the TRAF6 within the complex viral dsRNA:TLR3:TICAM1:TRAF6 (Gallus gallus)


name: SPRTN binds monoUb:K164-PCNA associated with POLH (Canis familiaris)


name: ursodeoxycholate + NAD(+) => 7-oxolithocholate + NADH + H(+)


name: SFTPs translocate from extracellular region to clathrin-coated vesicle (Canis familiaris)


name: Release of CSK from SRC (Rattus norvegicus)


name: S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 (Saccharomyces cerevisiae)


name: BAMBI interferes with the interaction of type I receptor with type II receptor (Sus scrofa)


name: Phosphorylation (Ser5) of RNA pol II CTD (Dictyostelium discoideum)


name: adenosine(1832) in 18S rRNA + S-adenosyl-L-methionine <=> N(6)-methyladenosine(1832) in 18S rRNA + S-adenosyl-L-homocysteine + H(+)


name: protein O-linked glycosylation via hydroxyproline


name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS (Drosophila melanogaster)


name: dihydro-6-demethylsterigmatocystin + S-adenosyl-L-methionine = dihydrosterigmatocystin + S-adenosyl-L-homocysteine + H(+)


name: oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor


name: dCMP + 2 phosphate + 2 H(+) => dCTP + 2 H2O


name: Recruitment of PI3K to plasma membrane (Rattus norvegicus)


name: FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Plasmodium falciparum)


name: Dissociation of p-Y427-SHC1 from insulin receptor (Bos taurus)


name: SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane (Danio rerio)


name: AFG3L2 degrades mitochondrial matrix proteins (Bos taurus)


name: SRC phosphorylates SPRY2 on Y55 and Y227 (Rattus norvegicus)


name: a flavonol 3-O-beta-D-glucoside + UDP-beta-L-rhamnose = a flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] + UDP + H(+)


name: tetrahydroanabasine + acetyl-CoA <=> ammodendrine + CoA


name: a ganglioside GM1 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GalNAc-GM1 (d18:1(4E)) + UDP + H(+)


name: cytidine(49) in tRNA precursor + S-adenosyl-L-methionine => 5-methylcytidine(49) in tRNA precursor + S-adenosyl-L-homocysteine + H(+)


name: NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 (Sus scrofa)


name: "nitric oxide reductase [NAD(P)(+), nitrous oxide-forming]"


name: 3-nitrotoluene + NADH + O2 => 4-methylcatechol + nitrite + NAD(+)


name: 12-epi-fischerindole U + chloride + 2-oxoglutarate + O2 + H(+) <=> 12-epi-fischerindole G + succinate + CO2 + H2O


name: an acyl-CoA + a 1,2-diacyl-sn-glycerol <=> a triacyl-sn-glycerol + CoA


name: glutathionylspermidine + ADP + phosphate + H(+) => spermidine + glutathione + ATP


name: Activation of SHP2 through the binding to phospho-Gab1 (Homo sapiens)


name: (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP


name: 2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 (Mus musculus)


name: PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O (Bos taurus)


name: POLRMT and POLG bind the mitochondrial L strand replication origin (OriL) (Gallus gallus)


name: Initial activation of proMMP2 by MMP1, 7 (Sus scrofa)


name: L-methionine + H(+) = 3-(methylsulfanyl)propanamine + CO2


name: Phosphorylation of SHP2 by SFKs (Bos taurus)


name: DHAP is converted to 1-acyl GO3P by GNPAT (Mus musculus)


name: 2',3'-cyclophospho-AMP + H2O = adenosine 2'-phosphate + H(+)


name: 4-amino-L-phenylalanyl-[peptidyl-carrier protein] + AMP + diphosphate => 4-amino-L-phenylalanine + holo-[peptidyl-carrier protein] + ATP


name: 4-(2-aminophenyl)-2,4-dioxobutanoate + L-leucine => 4-methyl-2-oxopentanoate + L-kynurenine


name: 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 NAD(+) = 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 8 NADH + 8 H(+)


name: pyruvate transmembrane transport in mitochondria


name: catechol + chloride + CO2 + NAD(+) => 2-chlorobenzoate + NADH + O2 + H(+)


name: Decreased Sympathetic Neurotensin Activity


name: ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Drosophila melanogaster)


name: an N,N'-diacetylchitobiosyl-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose => a beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)


name: an aromatic (S)-hydroxynitrile <=> an aromatic aldehyde + hydrogen cyanide


name: alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate


name: Nascent MT-CO1 binds to MITRAC, Mg2+, PE, CL (Mus musculus)


name: phosphonoacetate + H2O <=> acetate + phosphate + H(+)


name: TXLNA (IL14) binds syntaxin3 (Canis familiaris)


name: Formation of the 19S regulatory particle base precursor (Schizosaccharomyces pombe)


name: (8Z,11Z,14Z)-eicosatrienoate + O2 <=> (12S)-hydroperoxy-(8Z,10E,14Z)-eicosatrienoate


name: N-terminal L-methionyl-L-valyl-[protein] + acetyl-CoA <=> N-terminal N(alpha)-acetyl-L-methionyl-L-valyl-[protein] + CoA + H(+)


name: 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + (9Z)-hexadecenoyl-CoA = 1-hexadecanoyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: a 2-hydroxy-3-methyl fatty acyl-CoA => a 2-methyl-branched fatty aldehyde + formyl-CoA


name: complex III (ubiquinone to cytochrome c)


name: WNT:FZD complex promotes G-protein nucleotide exchange (Caenorhabditis elegans)


name: MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF (Danio rerio)


name: TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Drosophila melanogaster)


name: TBP and TFIIA bind TATA box on  ESR1:estrogen bound TFF1 gene promoter (Gallus gallus)


name: malonate + Na(+)(in) + H(+) => acetate + Na(+)(out) + CO2


name: acetate + ATP + H(+) => acetyl-AMP + diphosphate


name: S-octanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+) => octanoyl-CoA + H2O


name: Active FLT3 phosphorylates CDKN1B (Mus musculus)


name: F2R:ARRB1 binds MAPKs, SRC-1 (Rattus norvegicus)


name: methanesulfonate + FMNH2 + O2 = FMN + sulfite + formaldehyde + H2O + 2 H(+)


name: (2E)-butenoyl-[ACP] + NADPH + H(+) = butanoyl-[ACP] + NADP(+)


name: MDM2 homodimers auto-ubiquitinate (Mus musculus)


name: RHOQ translocates to the Golgi-associated vesicle membranes (Homo sapiens)


name: Src activation following P2Y purinoceptor activation (Bos taurus)


name: (1R,2R)-1,2-dihydrobenzene-1,2-diol + NADP(+) <=> catechol + NADPH + H(+)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine(in) <=> a 1,2-diacyl-sn-glycero-3-phosphocholine(out)


name: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Canis familiaris)


name: UBP43 binds IFNAR2 and prevents JAK1 interaction (Homo sapiens)


name: RAB:GTP recruits GBF1 to the Golgi membrane (Canis familiaris)


name: NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Bos taurus)


name: (3R)-1,2-didehydro-3-hydroxy-2,3-dihydrotabersonine + AH2 => (3R)-3-hydroxy-2,3-dihydrotabersonine + A


name: a ganglioside GT1b + CMP-N-acetyl-beta-neuraminate => a ganglioside GQ1b + CMP + H(+)


name: Constitutively active MAPK1 mutants are not dephosphorylated by DUSPs (Homo sapiens)


name: Ligation of DNA and formation of Holliday structures following repair synthesis (Canis familiaris)


name: ALOXE3 isomerises 12R-HpETE to HXA3 (Dictyostelium discoideum)


name: Recruitment of POLB to the AP site (Dictyostelium discoideum)


name: RND1 binds GTP (Saccharomyces cerevisiae)


name: (2R)-hydroxyoctanoate + FAD + H(+) <=> 2-oxooctanoate + FADH2


name: PANK2 phosphorylates PanK (Mus musculus)


name: vomilenine + NADPH + H(+) => (20S)-19,20-dihydrovomilenine + NADP(+)


name: CD320-mediated TCN2:RCbl uptake and delivery to lysosome (Mus musculus)


name: (R)-nicotine + A + H2O => (R)-6-hydroxynicotine + AH2


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Mus musculus)


name: IMP + L-aspartate + GTP => N(6)-(1,2-dicarboxyethyl)-AMP + GDP + phosphate + 2 H(+)


name: 3-O-(beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-alpha-L-Fuc)-L-seryl-[EGF-like domain protein] + UDP + H(+) => 3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP-alpha-D-galactose


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + octadecanoyl-CoA = 1-O-hexadecyl-2-acetyl-3-octadecanoyl-sn-glycerol + CoA


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Homo sapiens)


name: GAB1 phosphorylation by EGFR kinase (Bos taurus)


name: B4GALNT1 dimer transfers GalNAc to gangliosides (Danio rerio)


name: RHOT1 hydrolyzes GTP (Schizosaccharomyces pombe)


name: Caspase-9 binds DCC:DIP13alpha complex (Canis familiaris)


name: CHEK1 is recruited to resected DNA DSBs (Canis familiaris)


name: 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z)-eicosatrienoate + NAD(+) => 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z,13E)-eicosatetraenoate + NADH + H(+)


name: N(1)-methylpseudouridine(1191) in yeast 18S rRNA + S-adenosyl-L-methionine = N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine(1191) in yeast 18S rRNA + S-methyl-5'-thioadenosine + H(+)


name: Internalization of gap junction plaques (Canis familiaris)


name: NEDD8:AcM-UBE2F binds CRL5 E3 ubiquitin ligase complex (Homo sapiens)


name: PDE12 cleaves 2'-5' oligoadenylates  (Canis familiaris)


name: Trimerization of TRAIL:TRAIL receptor complex (Rattus norvegicus)


name: a globoside NORint + UDP-alpha-D-galactose => a globoside NOR2 + UDP + H(+)


name: SMDT1 assists in assembling MCU, MCUB, MICU1, MICU2 (or MICU3) yielding the MCU complex (Canis familiaris)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 (Dictyostelium discoideum)


name: PAK1 binds RAC1:GTP (Dictyostelium discoideum)


name: Sulfate is exported to the cytosol in exchange for dicarboxylate (Gallus gallus)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H2O = a 1-acyl-sn-glycero-3-phospho-L-serine + a fatty acid + H(+)


name: Gamma-Secretase Mediated ErbB4 Signaling Pathway


name: NGEF exchanges GTP for GDP on RHOA (Rattus norvegicus)


name: pyruvate + NH4(+) + NADH + H(+) => L-alanine + NAD(+) + H2O


name: IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 (Bos taurus)


name: Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane (Sus scrofa)


name: activation of nickel superoxide dismutase activity


name: ADM:CALCRL:RAMP2:G-alpha(s):GDP:G-beta:G-gamma exchanges GDP for GTP (Homo sapiens)


name: (R)-amygdalin + H2O <=> (R)-prunasin + D-glucose


name: Increased Central Nervous System Dopamine Activity


name: CHOL translocates from lysosome membrane to ER membrane (Dictyostelium discoideum)


name: ADRM1 binds 26S proteasome (Caenorhabditis elegans)


name: PRMT1,PRMT6 methylate arginine-4 of histone H4 (Canis familiaris)


name: Fe(III)-enterobactin + 3 H2O + H(+) => Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine] + 2 N-(2,3-dihydroxybenzoyl)-L-serine


name: urate(out) + Na(+)(in) => urate(in) + Na(+)(out)


name: tetradecanoate + ATP + H(+) = tetradecanoyl-AMP + diphosphate


name: RHOT1 hydrolyzes GTP (Caenorhabditis elegans)


name: (S)-1-pyrroline-5-carboxylate + NADPH + 2 H(+) => L-proline + NADP(+)


name: SIRT5 deacetylates Cytochrome C (Danio rerio)


name: HNF1B binds the WNT9B gene (Homo sapiens)


name: histone lactyltransferase (CoA-dependent) activity


name: Interleukin-5 receptor alpha subunit binds Interleukin-5 (Mus musculus)


name: PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane (Caenorhabditis elegans)


name: Glucagon binds to Glucagon receptor (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) = 1D-myo-inositol 1,2-cyclic phosphate + a 1,2-diacyl-sn-glycerol


name: (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + succinate + CO2 => N(6),N(6),N(6)-trimethyl-L-lysine + 2-oxoglutarate + O2


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerone 3-phosphate + hexadecanoate => 1-hexadecanoylglycerone 3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoate


name: Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 (Caenorhabditis elegans)


name: D-ribulose 5-phosphate => aldehydo-D-ribose 5-phosphate


name: 4-methylsulfanyl-2-oxobutanoate + L-kynurenine = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-methionine


name: USP8 deubiquitinates FZD to potentiate WNT signaling (Mus musculus)


name: (3R)-hydroxy-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA => (2E,17Z,20Z,23Z,26Z)-dotriacontapentaenoyl-CoA + H2O


name: FKRP dimer transfers RboP to matriglycan chain (Danio rerio)


name: trans-4-hydroxy-L-proline + a quinone = (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + a quinol + H(+)


name: Nephrin dimer:KIRREL binds FYN (Rattus norvegicus)


name: (E)-sinapoyl-CoA + NADPH + H(+) => (E)-sinapaldehyde + NADP(+) + CoA


name: thiophene-2-carbonyl-CoA + AH2 + O2 = 5-hydroxythiophene-2-carbonyl-CoA + A + H2O + H(+)


name: Allergen dependent IgE bound FCERI aggregation (Canis familiaris)


name: 2 oxidized [4Fe-4S]-[ferredoxin] + an aldehyde + H2O = 2 reduced [4Fe-4S]-[ferredoxin] + a carboxylate + 3 H(+)


name: N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP (Danio rerio)


name: C-terminal Hh fragments are bound by lectins (Canis familiaris)


name: FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2)) (Bos taurus)


name: L-seryl-[low-density-lipoprotein receptor] + ATP <=> O-phospho-L-seryl-[low-density-lipoprotein receptor] + ADP + H(+)


name: ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Xenopus tropicalis)


name: N-terminal L-alanyl-[ribosomal protein bS18] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-alanyl-[ribosomal protein bS18] + CoA + H(+)


name: "[ribosomal protein bS18]-alanine N-acetyltransferase"


name: HIPK2 phosphorylates TP53 (Homo sapiens)


name: SPNS2,MFSD2B transport S1P from cytosol to extracellular region (Sus scrofa)


name: (E)-caffeate + pyruvate + H(+) => (E)-caffeoylpyruvate + H2O


name: Phosphorylated Cdc6 is exported from the nucleus (Mus musculus)


name: choline <=> trimethylamine + acetaldehyde


name: down regulation of EGFR family signaling pathway


name: psilocybin + 2 S-adenosyl-L-homocysteine + 2 H(+) => norbaeocystin + 2 S-adenosyl-L-methionine


name: Fibrillin microfibril assembly (Danio rerio)


name: CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments (Drosophila melanogaster)


name: Release of docked serotonin loaded synaptic vesicle (Caenorhabditis elegans)


name: TPST1,2 transfer SO4(2-) from PAPS to PODXL2 (Rattus norvegicus)


name: Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Dictyostelium discoideum)


name: perillic acid-CoA ligase (AMP-forming) activity


name: Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Sus scrofa)


name: siamenoside I + UDP-alpha-D-glucose = mogroside V + UDP + H(+)


name: TFRC dimer binds 2xholoTF (Homo sapiens)


name: 3-(all-trans-hexaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine <=> 2-methoxy-6-(all-trans-hexaprenyl)phenol + S-adenosyl-L-homocysteine + H(+)


name: 7-epizingiberene + diphosphate => (2E,6E)-farnesyl diphosphate


name: RIPK3 binds p-S9-PRKN (Rattus norvegicus)


name: di-trans,octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine = di-trans,octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1->4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP + H(+)


name: sitosterol + reduced [NADPH--hemoprotein reductase] + O2 = (22S)-22-hydroxysitosterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: non-membrane spanning protein tyrosine phosphatase activity


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Rattus norvegicus)


name: an (omega-1)-hydroxy fatty acid + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => an (omega-1)-ethyl fatty acid + reduced [NADPH--hemoprotein reductase] + O2


name: ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Canis familiaris)


name: histone H3K4 deacetylase activity, hydrolytic mechanism


name: 1-(9Z-octadecenoyl)-2-acyl-sn-3-glycerol + a sphingomyelin => a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine


name: mycophenolate + D-glucuronate + H(+) => mycophenolic acid O-acyl-beta-D-glucuronide + H2O


name: 3-oxohexadecanoyl-CoA + CoA => tetradecanoyl-CoA + acetyl-CoA


name: (11R)-dihydroartemisinic aldehyde + NADP(+) => (+)-artemisinic aldehyde + NADPH + H(+)


name: ZEB1 recruits SETD8 to CDH1 gene promoter (Xenopus tropicalis)


name: Production of AA by iPLA2 upon FCGR activation (Rattus norvegicus)


name: deacetylcephalosporin C + acetate + H(+) => cephalosporin C + H2O


name: POU5F1 (OCT4), STAT3 bind the SALL4 promoter (Homo sapiens)


name: N(alpha)-acetyl-L-methionyl-L-alanyl-L-serine + H2O => L-alanyl-L-serine + N-acetyl-L-methionine


name: NOSTRIN mediated translocation of eNOS from plasma membrane (Bos taurus)


name: CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 (Homo sapiens)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Saccharomyces cerevisiae)


name: GAL3ST1 transfers sulfate to GalCer,LacCer (Danio rerio)


name: dodecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 5-hydroxydodecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: COMT transfers Met to DA to form 3MT (Xenopus tropicalis)


name: pyruvate family amino acid catabolic process


name: p-Y420-FYN is phosphorylated on S21 (Xenopus tropicalis)


name: L-histidine + 2-oxoglutarate = 3-(imidazol-5-yl)pyruvate + L-glutamate


name: Insulin degradation (Xenopus tropicalis)


name: Interaction and oligomerization of MALT1 to Bcl10 (Sus scrofa)


name: Activation of JAK kinases (Xenopus tropicalis)


name: Active G alpha (i)–i1/i2/i3 binds RGS proteins (Rattus norvegicus)


name: GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Sus scrofa)


name: 2-amino-4-hydroxypteridine + O2 = 2-amino-4,7-dihydroxypteridine + chemical entity


name: L-lysyl(37)-[histone H3] + 3 S-adenosyl-L-methionine => N(6),N(6),N(6)-trimethyl-L-lysyl(37)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)


name: plastid PEP RNA polymerase core enzyme binding


name: sn-glycerol 3-phosphate + an acyl-CoA = a 2-acyl-sn-glycerol 3-phosphate + CoA


name: De novo formation of eIF2:GTP (Danio rerio)


name: nocamycin E + S-adenosyl-L-methionine = nocamycin I + S-adenosyl-L-homocysteine


name: (16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA + CO2 + CoA


name: all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity


name: SUMOylation of TOP2A with SUMO1 (Bos taurus)


name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) (Xenopus tropicalis)


name: L-alanyl-L-aspartate + H2O <=> L-aspartate + L-alanine


name: Translocation of STAT1 dimer to nucleus (Homo sapiens)


name: 11-beta-hydroxysteroid dehydrogenase (NADP+) activity


name: GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Dictyostelium discoideum)


name: N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => an N-(2,3-dihydroxyhexacosanoyl)-(4R)-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O


name: oxPL binds LBP (Dictyostelium discoideum)


name: 1,3-beta-D-glucan:p-Y15-CLEC7A:SYK phosphorylates PLCG (Homo sapiens)


name: Phosphorylated Cdc6 is exported from the nucleus (Danio rerio)


name: a cytidine in 25S rRNA + S-adenosyl-L-methionine <=> a 5-methylcytidine in 25S rRNA + S-adenosyl-L-homocysteine + H(+)


name: Transport of MHC II:Ii complex to plasma membrane (Canis familiaris)


name: inhibition of cell wall biogenesis, MAPKKK cascade


name: Nitrite ion and HNO2 form a conjugated acid-base pair (Homo sapiens)


name: CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Canis familiaris)


name: (2E)-pentadecenoyl-CoA + FADH2 => pentadecanoyl-CoA + FAD + H(+)


name: SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Xenopus tropicalis)


name: (S)-cheilanthifoline + reduced [NADPH--hemoprotein reductase] + O2 => (S)-stylopine + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: activation of antifungal peptide biosynthetic process


name: SHP2 dephosphorylates Tyr 992 on EGFR (Canis familiaris)


name: Fibronectin degradation by MMP14 (Xenopus tropicalis)


name: PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates (Caenorhabditis elegans)


name: L-lysyl-[protein] + O2 + H2O = (S)-2-amino-6-oxohexanoyl-[protein] + H2O2 + NH4(+)


name: ATP-dependent H3-H4 histone complex chaperone activity


name: ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) (Rattus norvegicus)


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Drosophila melanogaster)


name: Activated NTRK3 binds SRC (Rattus norvegicus)


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Mus musculus)


name: PREX2 binds PTEN and inhibits it (Canis familiaris)


name: LHPP:Mg2+ dimer hydrolyses PPi (Mus musculus)


name: SCF-beta-TrCP ubiquitinylates IkB (Bos taurus)


name: PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170) (Rattus norvegicus)


name: catalytic activity, acting on a glycoprotein


name: Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)


name: MLCL is acylated to CL by LCLAT1 (ER) (Xenopus tropicalis)


name: IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 binds STAT3 (Bos taurus)


name: (2E,6E)-farnesyl diphosphate + 2 H2O => 7-epi-ent-eudesmane-5,11-diol + diphosphate


name: IP6 transports from the cytosol to the nucleus (Drosophila melanogaster)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Caenorhabditis elegans)


name: (S)-malate + CoA + H(+) => (S)-malyl-CoA + H2O


name: tRNA(Lys) + L-serine => L-seryl-tRNA(Lys) + H2O


name: CRTAM binds to NECL2 (Rattus norvegicus)


name: Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Sus scrofa)


name: ERK1/2-activated AP1 complex binds KDM6B promoter (Homo sapiens)


name: 3-oxopropanoate + NH4(+) => (Z)-3-aminoacrylate + H2O + H(+)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-guanosine) in mRNA + S-adenosyl-L-homocysteine + H(+)


name: 4-methylumbelliferone sulfate(out) + ADP + phosphate + H(+) => 4-methylumbelliferone sulfate(in) + ATP + H2O


name: (2E,6E)-farnesyl diphosphate + H2O <=> (2Z,6E)-hedycaryol + diphosphate


name: Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Bos taurus)


name: GST dimers cleave AZA to 6MP (Dictyostelium discoideum)


name: NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Xenopus tropicalis)


name: ARL3:GTP binds the UNC119B complex (Bos taurus)


name: KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Rattus norvegicus)


name: (3R)-hydroxytetracosanoyl-CoA + NAD(+) = 3-oxotetracosanoyl-CoA + NADH + H(+)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H2O <=> 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycerol + phosphate


name: melibiose + H2O = D-galactose + D-glucose


name: Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Sus scrofa)


name: P-type potassium:proton transporter activity


name: p-STAT1 binds p-STAT3 (Rattus norvegicus)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenosine) in mRNA + S-adenosyl-L-methionine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(N(6),2'-O-dimethyladenosine) in mRNA + S-adenosyl-L-homocysteine + H(+)


name: crizotinib-resistant ALK mutants don't bind crizotinib (Homo sapiens)


name: negative regulation of SREBP-mediated signaling pathway in presence of oxygen


name: PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Danio rerio)


name: FPRL2 receptor binds a wide range of ligands (Rattus norvegicus)


name: calciol + reduced [NADPH--hemoprotein reductase] + O2 => calcidiol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: dodecanamide + H2O = dodecanoate + NH4(+)


name: BRD7 promotes EP300-mediated acetylation of TP53 (Homo sapiens)


name: Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Drosophila melanogaster)


name: 20-hydroxy-11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + reduced [NADPH--hemoprotein reductase] + O2


name: LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 (Sus scrofa)


name: tetX HC:LC binds target cell-surface gangliosides (Homo sapiens)


name: SGT1:HSP90 binds inactive NLRP3 (Xenopus tropicalis)


name: 5-(3,3-dimethylguanidino)-2-oxopentanoate + glycine => N(omega),N(omega)-dimethyl-L-arginine + glyoxylate


name: epoxyqueuosine(34) in tRNA + AH2 <=> queuosine(34) in tRNA + A + H2O


name: Homer1,2,3 binds mGluR1a,5 (Xenopus tropicalis)


name: LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Mus musculus)


name: sn-glycerol 3-phosphate + FAD + H(+) = dihydroxyacetone phosphate + FADH2


name: 1-O-hexadecyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine <=> 1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine


name: L-ascorbate 6-phosphate + H2O => 3-dehydro-L-gulonate 6-phosphate


name: a 2-(all-trans-polyprenyl)phenol + NADPH + O2 + H(+) => a 3-(all-trans-polyprenyl)benzene-1,2-diol + NADP(+) + H2O


name: AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Bos taurus)


name: Antizyme OAZ binds to Ornithine decarboxylase (Caenorhabditis elegans)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR1 (Mus musculus)


name: lipid A + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) <=> lipid A 4'-(2-aminoethyl diphosphate) + a 1,2-diacyl-sn-glycerol


name: H2O2 + NAD(+) => 1,2-dihydro-beta-NAD + O2 + H(+)


name: RHOA GAPs stimulate RHOA GTPase activity (Drosophila melanogaster)


name: PTEN mRNA translation is inhibited by miR-137 (Homo sapiens)


name: Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Rattus norvegicus)


name: Regeneration of eEF1A:GTP by eEF1B activity (Rattus norvegicus)


name: 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine => N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: Trimethylation of CD274 gene promoter by EZH2 (Xenopus tropicalis)


name: Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Bos taurus)


name: 1-O-tetracosyl (9Z)-octadecenoate + CoA => tetracosan-1-ol + (9Z)-octadecenoyl-CoA


name: Phosphorylation of PLC-gamma1 (Xenopus tropicalis)


name: 6 Fe(III)-[cytochrome c] + NH4(+) + 2 H2O <=> 6 Fe(II)-[cytochrome c] + nitrite + 8 H(+)


name: ent-copalyl diphosphate => ent-cassa-12,15-diene + diphosphate


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 binds GAB1 (Sus scrofa)


name: Fibronectin degradation by CTSG (Bos taurus)


name: O-methyl-L-tyrosine + anthranilate + S-adenosyl-L-methionine + 2 ATP = (-)-4'-methoxycyclopeptine + 2 AMP + S-adenosyl-L-homocysteine + 2 diphosphate + 2 H(+)


name: (R)-adrenaline + S-adenosyl-L-homocysteine + H(+) => (R)-noradrenaline + S-adenosyl-L-methionine


name: PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane (Saccharomyces cerevisiae)


name: Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Drosophila melanogaster)


name: nicotianamine + 3 S-methyl-5'-thioadenosine + 3 H(+) => 3 S-adenosyl-L-methionine


name: xanthine + H2O + NAD+ => urate + NADH + H+ (Gallus gallus)


name: N(6)-methyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-homocysteine + H(+)


name: 5alpha-cholestan-3-one + NADP(+) <=> cholest-4-en-3-one + NADPH + H(+)


name: bHEXA,bHEXS hydrolyze GM2A:SM2 (Homo sapiens)


name: orotate:monoatomic anion antiporter activity


name: a tRNA precursor + 2 CTP => a tRNA with a 3' CC end + 2 diphosphate


name: 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 => 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: menaquinone-7 + NADH + H(+) = menaquinol-7 + NAD(+)


name: (9Z)-hexadecenoate + ATP + CoA <=> (9Z)-hexadecenoyl-CoA + AMP + diphosphate


name: MARK3 phosphorylates MITF-M on S173 (Mus musculus)


name: NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Drosophila melanogaster)


name: Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment (Homo sapiens)


name: chondroitin sulfate proteoglycan binding


name: (R)-noradrenaline + S-adenosyl-L-methionine => (R)-adrenaline + S-adenosyl-L-homocysteine + H(+)


name: 5-HEDH dehydrogenates 5(S)-Hp-18(R)-HEPE to 18(R)-RvE2 (Homo sapiens)


name: PNPLA4 hydrolyzes TAG (Xenopus tropicalis)


name: Resumption of elongation after recovery from pausing (Sus scrofa)


name: 3-oxosphinganine + NADPH + H(+) => sphinganine + NADP(+)


name: 2-methyloctadecanoate + CoA + H(+) => 2-methyloctadecanoyl-CoA + H2O


name: GRK2 sequesters activated Gq (Sus scrofa)


name: VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane (Xenopus tropicalis)


name: glutaryl-CoA + oxidized [electron-transfer flavoprotein] + H(+) <=> (2E)-glutaconyl-CoA + reduced [electron-transfer flavoprotein]


name: d-4,5 unsaturated beta-glucuronyl hydrolase activity


name: N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]


name: Interleukin-1 receptor type 1: Interleukin 1 binds Interleukin-1 receptor accessory protein, membrane associated isoform (Rattus norvegicus)


name: PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 (Saccharomyces cerevisiae)


name: Expression U2 small nuclear ribonucleoprotein A' (Homo sapiens)


name: Collagen type XII degradation by MMP12 (Xenopus tropicalis)


name: PI3K phosphorylates PIP2 to PIP3 (Bos taurus)


name: vascular endothelial growth factor receptor 2 binding


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycerol + UDP-alpha-D-galactose = 1-(9Z-octadecenoyl)-2-hexadecanoyl-3-beta-D-galactosyl-sn-glycerol + UDP + H(+)


name: orotate(in) + 2 H(+)(in) => orotate(out) + 2 H(+)(out)


name: Reduction of desmosterol to cholesterol (Xenopus tropicalis)


name: heme b + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = biliverdin IXalpha + CO + Fe(2+) + 3 oxidized [NADPH--hemoprotein reductase] + 3 H2O + H(+)


name: CORIN(802-1042) hydrolyses NPPA to form NPPA(124-151) (Rattus norvegicus)


name: PC is exchanged with PI by PITPNB (Dictyostelium discoideum)


name: a 1-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine => a 1-acyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycerol


name: HSPG2 (perlecan) is cleaved by BMP1, TLL1, TLL2, Cathepsin L1 (Caenorhabditis elegans)


name: FAD-dependent histone H3K9me/H3K9me2 demethylase activity


name: Cleavage of mRNA at the 3'-end (Sus scrofa)


name: 1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + S-adenosyl-L-homocysteine + H(+) => 1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine


name: Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA (Gallus gallus)


name: SMAC (DIABLO) binds XIAP (Rattus norvegicus)


name: Association of procollagen type XXII (Sus scrofa)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 (Sus scrofa)


name: FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX (Caenorhabditis elegans)


name: CREB1 binds IL-10 promoter (Homo sapiens)


name: S100A8:S100A9:AA:Ca(2+) binds NOX2 complex (Rattus norvegicus)


name: 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA => (9Z,12Z)-octadecadienoyl-CoA + a 1-acyl-sn-glycero-3-phosphocholine


name: Translocation of caspase-3 to the nucleus (Mus musculus)


name: dTDP-beta-L-4-epi-vancosamine + devancoaminyl-vancomycin <=> chloroorienticin B + dTDP + H(+)


name: Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End (Homo sapiens)


name: FPR is a receptor for formyl peptides (Canis familiaris)


name: (9Z)-octadecenamide + H2O = (9Z)-octadecenoate + NH4(+)


name: 5-N(alpha)-glycyl-dTMP in DNA + AH2 + S-adenosyl-L-methionine <=> 5-C(alpha)-glycyl-dTMP in DNA + 5'-deoxyadenosine + L-methionine + A + H(+)


name: Recruitment of XPA and release of CAK  (Bos taurus)


name: L-methionyl-[protein] + a quinone + H2O = L-methionyl-(S)-S-oxide-[protein] + a quinol


name: TBC RabGAPs accelerate GTP hydrolysis by RAB35 (Mus musculus)


name: Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) (Schizosaccharomyces pombe)


name: H2O2 diffuses from the mitochondrial matrix to the cytosol (Homo sapiens)


name: ARL1 recruits TGN Golgin homodimers (Mus musculus)


name: L-cysteinyl-[protein] + NAD(+) = S-(ADP-D-ribosyl)-L-cysteinyl-[protein] + nicotinamide + H(+)


name: ALD3A1 oxidises 4HPCP to CXPA (Caenorhabditis elegans)


name: (6S)-NADHX + ADP <=> AMP + phosphate + NADH + H(+)


name: eIF3 and eIF1A bind to the 40S subunit (Bos taurus)


name: Caspase-7 translocates to the nucleus (Gallus gallus)


name: Recruitment of dystrophin, dystrobrevin and syntrophin proteins to the DGC (Sus scrofa)


name: blood platelet-activating factor acetyltransferase activity


name: Extension of pseudopodia by myosin-X in a PI3K dependent manner (Rattus norvegicus)


name: AKR1B15 reduces EST17b to E1 (Bos taurus)


name: alpha-D-ribose 1-methylphosphonate 5-triphosphate + H2O => alpha-D-ribose 1-methylphosphonate 5-phosphate + diphosphate + H(+)


name: CYP4F3 20-hydroxylates LTB4 (Homo sapiens)


name: L-fuculose + ATP => L-fuculose 1-phosphate + ADP + H(+)


name: MacA:MacB:TolC transports azithromycin from the cytosol to the periplasm (Homo sapiens)


name: Li(+)(out) + 2 hydrogencarbonate(out) + chloride(in) => Li(+)(in) + 2 hydrogencarbonate(in) + chloride(out)


name: Transfer of Ub from E2 to substrate and release of E2 (Rattus norvegicus)


name: AMOT proteins bind YAP1 (Canis familiaris)


name: Defective GLB1 does not hydrolyse a glycosaminoglycan (Homo sapiens)


name: (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O <=> 2-oxopent-4-enoate + formate + H(+)


name: butanoyl-CoA + hydrogencarbonate + ATP = (2R)-ethylmalonyl-CoA + ADP + phosphate + H(+)


name: AGO1,2:small RNA complexes interact with chromatin (Schizosaccharomyces pombe)


name: CYP51A1 demethylates LNSOL (Saccharomyces cerevisiae)


name: EGR2 and SREBF2 dimer bind SCD5 gene (Homo sapiens)


name: 3-demethylubiquinol-10 + S-adenosyl-L-methionine <=> ubiquinol-10 + S-adenosyl-L-homocysteine + H(+)


name: Phosphorylation of IRF-3/IRF7 and their release from the activated TLR3 complex  (Homo sapiens)


name: Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) (Drosophila melanogaster)


name: (2E,6E)-farnesyl diphosphate => (+)-thujopsene + diphosphate


name: (2E,6E)-farnesol + phosphate => (2E,6E)-farnesyl phosphate + H2O


name: LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 (Drosophila melanogaster)


name: positive regulation of MAP kinase activity


name: Addition of galactose to Core 6 glycoprotein (Rattus norvegicus)


name: SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix (Sus scrofa)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) <=> (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Arachidonate is oxidised to 12S-HpETE by ALOX12/15 (Homo sapiens)


name: MGMT binds alkylated DNA containing 6-O-methylguanine (Homo sapiens)


name: all-trans-4,4'-diaponeurosporene + 3 FADH2 => 15-cis-4,4'-diapophytoene + 3 FAD + 3 H(+)


name: all-trans-3-hydroxyretinol + 2 oxidized [adrenodoxin] + H2O => all-trans-retinol + 2 reduced [adrenodoxin] + O2 + 2 H(+)


name: cholesterol + reduced [NADPH--hemoprotein reductase] + O2 = (24S)-hydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Expression of MINK1/TNIK is positively regulated by ROS (Homo sapiens)


name: MICAL1 produces NADP+, H2O2 (Dictyostelium discoideum)


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 (Mus musculus)


name: 1-O-(1Z)-alkenyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + CoA => a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA


name: GCH1 reduces GTP to dihydroneopterin triphosphate (Dictyostelium discoideum)


name: 20S,23-dihydroxycholecalciferol + 2 reduced [adrenodoxin] + O2 + 2 H(+) => 20S,23,25-trihydroxycholecalciferol + 2 oxidized [adrenodoxin] + H2O


name: L-tryptophan + S-adenosyl-L-methionine => 2-methyl-L-tryptophan + S-adenosyl-L-homocysteine + H(+)


name: positive regulation of calcium-dependent ATPase activity


name: Formation of hydroxyallysine by LOX (Xenopus tropicalis)


name: USP7 deubiquitinates MDM2 (Homo sapiens)


name: EP3 receptor can bind PGE2 (Gallus gallus)


name: 2 reduced [4Fe-4S]-[ferredoxin] + glycine + 3 H(+) => aminoacetaldehyde + 2 oxidized [4Fe-4S]-[ferredoxin] + H2O


name: Monoubiquitination of FancD2 (Gallus gallus)


name: 10-hydroxydecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => decanoate + reduced [NADPH--hemoprotein reductase] + O2


name: biotinyl-5'-AMP + L-lysyl-[protein] = N(6)-biotinyl-L-lysyl-[protein] + AMP + 2 H(+)


name: (R)-N-tert-butylpiperazine-2-carboxamide + H2O => tert-butylamine + (R)-piperazine-2-carboxylate


name: SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine (Drosophila melanogaster)


name: cytosine + H2O + H(+) <=> uracil + NH4(+)


name: abieta-7,13-dien-18-al + H2O => abieta-7,13-dien-18,18-diol


name: PPA1 hydrolyzes pyrophosphate to orthophosphate (Drosophila melanogaster)


name: 3-oxopropanoate + NADH + H(+) => 3-hydroxypropanoate + NAD(+)


name: scyllo-inosose + NADPH + H(+) => scyllo-inositol + NADP(+)


name: myricetin 3-O-[(6-O-(E)-4-coumaroyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside] + CoA + H(+) => myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] + (E)-4-coumaroyl-CoA


name: PIAS4 SUMOylates PARP1 with SUMO2,3 (Mus musculus)


name: ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Sus scrofa)


name: heptyl sulfate + 2-oxoglutarate + O2 => heptanal + sulfate + succinate + CO2 + H(+)


name: 3-oxooctanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyoctanoyl-[ACP] + NADP(+)


name: GAB1 binds phosphatidylinositol-3,4,5-trisphosphate (Xenopus tropicalis)


name: GP1b-IX-V:13-3-3-zeta complexes with p85 PI3K (Bos taurus)


name: p-Y705-STAT3,p-Y641-STAT6 dissociate (Bos taurus)


name: 5-methylcytidine(48) in tRNA + S-adenosyl-L-homocysteine + H(+) => cytidine(48) in tRNA + S-adenosyl-L-methionine


name: TRPA1 tetramer binds TRPA1 antagonists (Dictyostelium discoideum)


name: (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) <=> a (5Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: (sulfur carrier)-H + L-cysteine => (sulfur carrier)-SH + L-alanine


name: Spherical HDL binds membrane-associated free cholesterol and phospholipids (Bos taurus)


name: DCP1-DCP2 complex decaps mRNA (Saccharomyces cerevisiae)


name: STAB2:ligand is endocytosed (Mus musculus)


name: L-Glutamine transport into neurons (Drosophila melanogaster)


name: (E)-caffeate + ATP + H(+) <=> (E)-caffeoyl-AMP + diphosphate


name: heptadecane + oxidized [NADPH--hemoprotein reductase] + CO2 + H2O + H(+) => octadecanal + reduced [NADPH--hemoprotein reductase] + O2


name: 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + ATP + CoA = 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate


name: S100A7 or S100A7A binds Zn2+ (Xenopus tropicalis)


name: D-serine + O2 + H2O <=> 3-hydroxypyruvate + H2O2 + NH4(+)


name: NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD (Danio rerio)


name: Addition of the first glucose to the N-glycan precursor by ALG6 (Mus musculus)


name: apo--[retinol-binding protein] + an all-trans-retinyl ester + a 2-acyl-sn-glycero-3-phosphocholine => all-trans-retinol--[retinol-binding protein] + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: jasmonate + S-adenosyl-L-methionine = methyl (-)-jasmonate + S-adenosyl-L-homocysteine


name: sphinganine + NADP(+) = 3-oxosphinganine + NADPH + H(+)


name: PCK2 phosphorylates OA to yield PEP (Danio rerio)


name: (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside(in) + ATP + H2O = (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside(out) + ADP + phosphate + H(+)


name: MCM4, MCM6 and MCM7 form a heterotrimer (Saccharomyces cerevisiae)


name: wogonin 7-O-beta-D-glucuronate + H2O <=> wogonin + D-glucuronate + H(+)


name: structural constituent of postsynaptic specialization


name: SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol (Danio rerio)


name: Activation of ISG15 by UBA7 E1 ligase (Sus scrofa)


name: Phosphorylation of PLC-gamma by p-BTK/p-SYK (Bos taurus)


name: GRB2-1:SOS1 binds p-Y427-SHC1 (Mus musculus)


name: MECP2 binds MOBP gene promoter (Homo sapiens)


name: BTRC binds p-S344, 347 NFE2L2 (Caenorhabditis elegans)


name: Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Mus musculus)


name: FRS2 is phosphorylated by active TrkA receptor (Xenopus tropicalis)


name: D-arginine + A + H2O = 5-guanidino-2-oxopentanoate + AH2 + NH4(+)


name: ACSL3,4 ligate CoA to AA to form AA-CoA (Danio rerio)


name: kanamycin A + ITP = 4'-inosinylylkanamycin A + diphosphate


name: eicosanoyl-CoA + O2 = (2E)-eicosenoyl-CoA + H2O2


name: 3-hydroxy-3-methylglutaryl CoA cleaving enzyme


name: Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Canis familiaris)


name: (3R,4S,5R)-3,4,5,6-tetrahydroxy-2-oxohexanoate => D-glyceraldehyde + 3-hydroxypyruvate


name: CFTR binds components of the ERAD machinery for ubiquitination and degradation (Sus scrofa)


name: OPN (osteopontin) degradation by MMP3, MMP7 (Danio rerio)


name: guanosine(34) in tRNA(Tyr) + queuine <=> queuosine(34) in tRNA(Tyr) + guanine


name: glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] (Xenopus tropicalis)


name: ACE2(18-805):Zn2+ hydrolyzes AGT(25-32) (Angiotensin-(1-8)) to AGT(25-31) (Angiotensin-(1-7)) (Mus musculus)


name: NAD(+) + NADPH + H(+)(in) => NADH + NADP(+) + H(+)(out)


name: RHOA binds effectors at the plasma membrane (Mus musculus)


name: FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP (Sus scrofa)


name: Co-precorrin-5A + H2O => Co-precorrin-5B + acetaldehyde + H(+)


name: Increased Cerebellum Nerve Growth Factor Activity


name: MSH2:MSH3 binds insertion/deletion loop of 2 bases or more (Mus musculus)


name: B4GALNT1 dimer transfers GalNAc to gangliosides (Xenopus tropicalis)


name: Fe(III)-di(C-5-deoxy-beta-D-glucosyl)-enterobactin + H2O <=> Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2} + H(+)


name: IFNAR2:JAK1:STAT2 binds type 1 interferon analogs (Homo sapiens)


name: N(6)-methyl-dAMP + diphosphate + H(+) => N(6)-methyl-dATP + H2O


name: Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Canis familiaris)


name: 2-cis-(+)-abscisate + H2O2 + H(+) => 2-cis-(+)-abscisic aldehyde + O2 + H2O


name: Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA (Mus musculus)


name: peptidyl-prolyl cis-trans isomerase activity


name: putrescine + O2 + H2O => 4-aminobutanal + H2O2 + NH4(+)


name: 5''-phosphoribostamycin + diphosphate => neamine + 5-phospho-alpha-D-ribose 1-diphosphate


name: negative regulation of lysine biosynthetic process via aminoadipic acid


name: sphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (4R)-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O


name: Phosphorylated heterodimers of ERBB2 KD mutants recruit GRB2:SOS1 through SHC1 (Homo sapiens)


name: bromide + 4-hydroxybenzoate + NADPH + O2 + 2 H(+) => 3-bromo-4-hydroxybenzoate + NADP(+) + 2 H2O


name: TRAF3:NIK binds TRAF2:cIAP1/2 (Xenopus tropicalis)


name: Transphosphorylation of JAK1 (Homo sapiens)


name: p85 regulatory unit of PI3K binds p-6Y-SYK (Gallus gallus)


name: 2,2',3-trihydroxydiphenyl ether + O2 + H(+) = 2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoate


name: MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs (Bos taurus)


name: (R)-glycerate + CO2 + NADP(+) => 2-hydroxy-3-oxosuccinate + NADPH + 2 H(+)


name: L-tryptophan(in) + Na(+)(in) <=> L-tryptophan(out) + Na(+)(out)


name: GTSE1 translocates to the nucleus (Rattus norvegicus)


name: GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a (Caenorhabditis elegans)


name: Activated MAPKs phosphorylate BRAF (Canis familiaris)


name: UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Homo sapiens)


name: (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate = 12-oxo-(5Z,8Z,10E,14Z)-eicosatetraenoate + H2O


name: 2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-D-ribose 5-phosphate


name: testosterone + reduced [NADPH--hemoprotein reductase] + O2 => 16beta,17beta-dihydroxyandrost-4-en-3-one + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: decan-1-ol + reduced [NADPH--hemoprotein reductase] + O2 <=> 1,3-decanediol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: negative regulation of hydrogen sulfide biosynthetic process


name: PLK1 binds phosphorylated condensin II complex (Plasmodium falciparum)


name: FMN(in) + adenosine 3',5'-bisphosphate(out) = FMN(out) + adenosine 3',5'-bisphosphate(in)


name: 4-terpineol + diphosphate => (2E)-geranyl diphosphate + H2O


name: CHD1L is recruited to GG-NER site (Sus scrofa)


name: a 1-O-alkyl-sn-glycero-3-phosphate + H2O <=> a 1-O-alkyl-sn-glycerol + phosphate


name: Phosphorylated MOB1A proteins associate with LATS proteins (Sus scrofa)


name: sphinga-(4E,8E)-dienine + hexadecanoyl-CoA = N-hexadecanoylsphinga-(4E,8E)-dienine + CoA + H(+)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[16] (Drosophila melanogaster)


name: PKA phosphorylates DARPP-32 on Thr34 (Xenopus tropicalis)


name: 2,3-didehydroadipoyl-CoA + acetyl-CoA = 3-oxo-5,6-didehydrosuberyl-CoA + CoA


name: Interaction of Tie2 with Ang1 (Mus musculus)


name: 1-O-alkyl-3-acylglycerol + a monoacyl-sn-glycero-3-phosphocholine => 1-O-alkylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: ppDVL binds DAAM1 (Drosophila melanogaster)


name: PTPN1 (PTP1B) dephosphorylates tyrosine-24 of ANXA2 (Annexin-2) (Drosophila melanogaster)


name: soppiline C + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+) => soppiline B + 3 reduced [NADPH--hemoprotein reductase] + 3 O2


name: NaDC1 co-transports dicarboxylic acids and a sodium ion (Canis familiaris)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleoside)-ribonucleotide in mRNA + S-adenosyl-L-methionine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleoside)-(2'-O-methyl-ribonucleotide) in mRNA + S-adenosyl-L-homocysteine + H(+)


name: (4,5-dihydro-5-oxofuran-2-yl)-acetate + H2O = 3-oxoadipate + H(+)


name: 5-diphospho-1D-myo-inositol 1,3,4,6-tetrakisphosphate + H2O => 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate + H(+)


name: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sphinganine + H2O => sphinganine + (5Z,8Z,11Z,14Z)-eicosatetraenoate


name: SEMA4D interacts with Plexin-B1:ErbB2 (Mus musculus)


name: Activated FGFR4:p-FRS binds GRB2:SOS1 (Rattus norvegicus)


name: Active FLT3:GRB2 binds SOS1 (Bos taurus)


name: WTS binds to SAV (Drosophila melanogaster)


name: AKR1C3 reduces atRAL to atROL (Caenorhabditis elegans)


name: atRAL is reduced to atROL (Canis familiaris)


name: Activated JNKs phosphorylate c-JUN (Drosophila melanogaster)


name: c-FOS activation by phospho ERK1/2 (Bos taurus)


name: 12-deshydroxyl okaramine E + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = 3-desmethyl okaramine B + 2 oxidized [NADPH--hemoprotein reductase] + 2 H2O + 2 H(+)


name: RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Rattus norvegicus)


name: 1-deoxypentalenate + reduced 2[4Fe-4S]-[ferredoxin] + O2 + 2 H(+) = pentalenate + oxidized 2[4Fe-4S]-[ferredoxin] + H2O


name: L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine + H(+)


name: "peptide chain release factor N(5)-glutamine methyltransferase"


name: 4-O-(beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranosyl)-(2S,4S)-4-hydroxyproline + H2O <=> 4-O-(beta-L-arabinofuranosyl)-(2S,4S)-4-hydroxyproline + beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose


name: Release of GNB5:RGS dimers from CCT/TRiC (Caenorhabditis elegans)


name: Nuclear PHD1,3 hydroxylates proline residues on HIF1A (Gallus gallus)


name: PIAS3 SUMOylates RELA with SUMO3 (Gallus gallus)


name: pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity


name: [(1->4)-beta-D-mannuronosyl](n) + GDP-alpha-D-mannuronate <=> [(1->4)-beta-D-mannuronosyl](n+1) + GDP + H(+)


name: 2'-deamino-2'-hydroxyparomamine + UDP-alpha-D-kanosamine = kanamycin X + UDP + H(+)


name: Aryl Hydrocarbon Receptor Agonists [MoA]


name: PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Sus scrofa)


name: nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA (Homo sapiens)


name: Hh-Np traffics to the plasma membrane (Mus musculus)


name: SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Xenopus tropicalis)


name: (13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA + malonyl-CoA + H(+) => 3-oxo-(15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + CO2 + CoA


name: Phosphorylation of MEF2 proteins by p38 (Drosophila melanogaster)


name: (2E,6E)-farnesyl diphosphate <=> (E)-beta-farnesene + diphosphate


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Danio rerio)


name: adenosine(N)/adenosine(N+1) in rRNA + 4 S-adenosyl-L-methionine = N(6)-dimethyladenosine(N)/N(6)-dimethyladenosine(N+1) in rRNA + 4 S-adenosyl-L-homocysteine + 4 H(+)


name: (3S)-3-hydroxydodecanoyl-CoA + NAD(+) = 3-oxododecanoyl-CoA + NADH + H(+)


name: Luteinizing hormone is a heterodimer (Mus musculus)


name: p62 binds ubiquitinated mitochondrial substrates (Xenopus tropicalis)


name: aryl-aldehyde dehydrogenase (NADP+) activity


name: PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus (Mus musculus)


name: mannosyl-alpha-1->6-inositol phospho-N-tetracosanoylsphinganine + GDP + H(+) => N-tetracosanoylsphinganine-(1D-myo-inositol) + GDP-alpha-D-mannose


name: p-S446-IRF5 dimer translocates to the nucleus (Danio rerio)


name: MITF-M-dependent CDKN1A expression (Homo sapiens)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleoside) in mRNA + S-adenosyl-L-homocysteine + H(+)


name: retinal + O2 + H2O => retinoate + H2O2 + H(+)


name: Active LTK receptor phosphorylates SHC1 (Homo sapiens)


name: 4-prenylphlorisovalerophenone + dimethylallyl diphosphate => deoxyhumulone + diphosphate


name: SCD5 desaturates ST-CoA to OLE-CoA (Caenorhabditis elegans)


name: PP2A-B56 dephosphorylates centromeric cohesin (Xenopus tropicalis)


name: 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one (Xenopus tropicalis)


name: CHUK, IKBKB phosphorylate RIPK1 at S25 (Homo sapiens)


name: Defective LARGE does not transfer Xyl from UDP-Xyl to GlcA (Homo sapiens)


name: Collagen type II degradation by MMP15 (Canis familiaris)


name: L-galactonate + NADP(+) <=> aldehydo-D-galacturonate + NADPH + H(+)


name: ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Drosophila melanogaster)


name: (S)-cystathionine ketimine + NADPH + 2 H(+) => (3R,5S)-2,3,5,6,7-pentahydro-1,4-thiazepine-3,5-dicarboxylate + NADP(+)


name: Cargo Recognition And Sorting (Caenorhabditis elegans)


name: ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 (Rattus norvegicus)


name: MIR181C microRNA binds 3'UTR of NOTCH4 mRNA (Homo sapiens)


name: a 2-amino-4-hydroxypteridine + H2O + H(+) => a 2,4-dihydroxypteridine + NH4(+)


name: superoxide dismutase copper chaperone activity


name: SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol (Mus musculus)


name: RNA polymerase II CTD heptapeptide repeat S5 kinase activity


name: Formation of the SET1B complex (Xenopus tropicalis)


name: glyoxylate + L-methionine = 4-methylsulfanyl-2-oxobutanoate + glycine


name: 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus (Rattus norvegicus)


name: PPM1A protein phosphatase binds phosphorylated SMAD2/3 (Sus scrofa)


name: 14-3-3 proteins bind AKT-phosphorylated FOXO3 (Xenopus tropicalis)


name: octadecanoate + L-phenylalanine => N-octadecanoyl-L-phenylalanine + H2O


name: CD274 ubiquitination by SPOP:CUL3:RBX1 complex (Caenorhabditis elegans)


name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators (Danio rerio)


name: MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG (Rattus norvegicus)


name: MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Rattus norvegicus)


name: thiamine diphosphate(in) => thiamine diphosphate(out)


name: Dephosphorylation of Gab1 by SHP2 (Homo sapiens)


name: IgG binds the surface of the amastigote form of Leishmania (Homo sapiens)


name: trans-Golgi Network Coat Activation (Mus musculus)


name: ATXN3 family cleave Ub chains (Mus musculus)


name: 3-nitrobenzaldehyde + H2O2 => 3-nitrobenzyl alcohol + O2


name: Phosphorylation of GAB2 by SFKs (Xenopus tropicalis)


name: bis-D-fructose 2',1:2,1'-dianhydride + H2O <=> inulobiose


name: thiamine triphosphate phosphatase activity


name: N-(8'-oxogeranyl)-L-glutamate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+) => N-(8'-hydroxygeranyl)-L-glutamate + reduced [NADPH--hemoprotein reductase] + O2


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> terpentedienyl diphosphate


name: p-PRKRA dimer binds PKR (Canis familiaris)


name: PTEN undergoes monoubiquitination (Drosophila melanogaster)


name: NFKB1:RELA translocates from the cytosol to the nucleus (Drosophila melanogaster)


name: GSK3B phosphorylates p-S73 MITF-M at residue S69 (Drosophila melanogaster)


name: L-proline + L-tryptophan + 2 ATP = brevianamide F + 2 AMP + 2 diphosphate + 2 H(+)


name: FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Xenopus tropicalis)


name: PIAS1,4 SUMOylate CASP8AP2 with SUMO1 (Homo sapiens)


name: DMGDH:FAD oxidatively demethylates DMGLY to SARC (Bos taurus)


name: beta-D-glucosyl-N-(9Z-octadecenoyl)-sphing-4E-enine + cholesterol => N-(9Z-octadecenoyl)-sphing-4-enine + cholesteryl 3-beta-D-glucoside


name: L-alanyl-L-aspartate(out) + ATP + H2O = L-alanyl-L-aspartate(in) + ADP + phosphate + H(+)


name: ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans (Mus musculus)


name: ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Homo sapiens)


name: activation of protein amino acid phosphorylation


name: protochlorophyllide a + 2 oxidized [2Fe-2S]-[ferredoxin] => 3,8-divinyl protochlorophyllide a + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+)


name: New CENPA-containing nucleosomes are deposited at the centromere (Bos taurus)


name: (2R)-2-hydroperoxydodecanoate + H(+) = undecanal + CO2 + H2O


name: apo-[aryl-carrier protein] + CoA => holo-[aryl-carrier protein] + adenosine 3',5'-bisphosphate + H(+)


name: sulfate + ATP + H(+) = adenosine 5'-phosphosulfate + diphosphate


name: CYP2E1 monooxygenates APAP to NAPQI (Dictyostelium discoideum)


name: phosphorelay response regulator activity


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane (Bos taurus)


name: (Z)-desulfoglucotropeolin + 3'-phosphoadenylyl sulfate = (Z)-glucotropeolin + adenosine 3',5'-bisphosphate + H(+)


name: kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin (Bos taurus)


name: p-S407,Y641-STAT6 is dimerized (Xenopus tropicalis)


name: LNK binds to p-KIT and inhibit downstream signaling (Homo sapiens)


name: glycyl-L-glutamine(out) + H(+)(out) = glycyl-L-glutamine(in) + H(+)(in)


name: prostaglandin E2(in) + a dicarboxylate(out) => prostaglandin E2(out) + a dicarboxylate(in)


name: SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Drosophila melanogaster)


name: eIF3 and eIF1A bind to the 40S subunit (Sus scrofa)


name: gamma-L-glutamyl-L-alaninol + H2O <=> L-alaninol + L-glutamate


name: platelet-derived growth factor receptor binding


name: negative regulation of cAMP-mediated signaling


name: DCN (decorin) degradation by MMP2, MMP3, MMP7 (Homo sapiens)


name: HDAC3 containing complexes deacetylate histone (Mus musculus)


name: p-PKR dimer phosphorylates SNCA (Sus scrofa)


name: hancockiamide D + (E)-cinnamate + ATP = hancockiamide A + AMP + diphosphate


name: N-ethylglycine + O2 + H2O <=> ethylamine + glyoxylate + H2O2


name: Sec is reduced to H2Se by PXLP-K259-SCLY dimer (Rattus norvegicus)


name: XPO1:BACH1:Hemes are transported out of the nucleus (Canis familiaris)


name: SREBP1A,1C binds the SCD gene (Homo sapiens)


name: AMPK is dephosphorylated (Gallus gallus)


name: 2-MAG and DAG are transacylated to TAG by PNPLA2/3 (Xenopus tropicalis)


name: Endocytosis of TRAM (TICAM2) (Canis familiaris)


name: scutellarein 7-methyl ether + S-adenosyl-L-methionine <=> cirsimaritin + S-adenosyl-L-homocysteine + H(+)


name: L-erythro-7,8-dihydrobiopterin + NADP(+) => L-sepiapterin + NADPH + H(+)


name: regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolic process


name: N-formylmethanofuran + 5,6,7,8-tetrahydromethanopterin + H(+) = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + methanofuran


name: (3R)-hydroxy-(23Z,26Z,29Z,32Z)-octatriacontatetraenoyl-CoA => (2E,23Z,26Z,29Z,32Z)-octatriacontapentaenoyl-CoA + H2O


name: DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP (Canis familiaris)


name: activation of Mn, Fe superoxide dismutase


name: labda-7,13(16),14-triene + diphosphate => (13E)-labda-7,13-dien-15-yl diphosphate


name: Tropoelastin forms aggregate globules (Mus musculus)


name: [(1->2)-beta-D-glucosyl](n+1) + UDP + H(+) => [(1->2)-beta-D-glucosyl](n) + UDP-alpha-D-glucose


name: L-threonyl-[myosin heavy-chain] + ATP <=> O-phospho-L-threonyl-[myosin heavy-chain] + ADP + H(+)


name: a 3-O-{alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-alpha-D-GalNAc}-L-threonyl-[protein] + CMP + H(+) => 3-O-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-alpha-D-GalNAc]-L-Thr-[protein] + CMP-N-acetyl-beta-neuraminate


name: (2-aminobenzyl)malonyl-CoA + O2 + H(+) => (E)-2-aminocinnamoyl-CoA + H2O2 + CO2


name: chlorophyllide a + H2O + H(+) = 8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d + methanol + CO2


name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Homo sapiens)


name: Proteasome-mediated degradation of PolyUb-FBXL7 (Sus scrofa)


name: CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments (Caenorhabditis elegans)


name: FAR1 reduces PalmCoA to HXOL (Canis familiaris)


name: 2-hydroxy-3-oxosuccinate + NADPH + 2 H(+) => (R)-glycerate + CO2 + NADP(+)


name: Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) (Homo sapiens)


name: (12S)-hydroperoxy-(14R,15S)-epoxy-(5Z,8Z,10E)-eicosatrienoate => (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2


name: N(6)-dimethylallyladenosine(37) in tRNA + (sulfur carrier)-SH + AH2 + S-adenosyl-L-methionine => 2-thio-N(6)-dimethylallyladenosine(37) in tRNA + (sulfur carrier)-H + 5'-deoxyadenosine + L-methionine + A + H(+)


name: RHOC translocates to the endoplasmic reticulum membrane (Schizosaccharomyces pombe)


name: IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 binds PI3K regulatory subunits (Homo sapiens)


name: EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch (Canis familiaris)


name: O-atom dealkylation of dextromethorphan (Caenorhabditis elegans)


name: 2,6,10,14-tetramethylpentadecanoate + CoA + H(+) => pristanoyl-CoA + H2O


name: LTN1 K48 polyubiquitinates the nascent peptide in NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide (Danio rerio)


name: a (2E,4Z)-dienoyl-CoA + NADPH + H(+) => a 4,5-saturated-(2E)-enoyl-CoA + NADP(+)


name: ETA is phosphorylated to PETA by CHK/ETNK (Schizosaccharomyces pombe)


name: (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + GDP-alpha-D-mannose => (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-3-phospho-glycerate + GDP + H(+)


name: AVPR1A,2 bind AVPR antagonists (Canis familiaris)


name: 3,3-dimethylbutan-2-one + hydrogen cyanide = (2S)-2-hydroxy-2-methyl-3,3-dimethylbutanenitrile


name: L-tryptophan + NAD(+) + H2O <=> indole-3-pyruvate + NH4(+) + NADH + H(+)


name: Joining of adjacent Okazaki fragments (Mus musculus)


name: UDP-alpha-D-galacturonate(in) + UMP(out) <=> UDP-alpha-D-galacturonate(out) + UMP(in)


name: propanoyl-CoA + L-lysyl-[protein] = N(6)-propanoyl-L-lysyl-[protein] + CoA + H(+)


name: putrebactin + 2 AMP + 2 diphosphate + 2 H(+) => 2 N-(3-carboxypropanoyl)-N-hydroxyputrescine + 2 ATP


name: HDACs deacetylate p-STAT3 dimers (Rattus norvegicus)


name: ME1 tetramerizes (Drosophila melanogaster)


name: SGCG,SGCZ and SGCA, SGCE bind SGCB:SGCD (Bos taurus)


name: glycochenodeoxycholate + 3'-phosphoadenylyl sulfate => glycochenodeoxycholate 7-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one (Dictyostelium discoideum)


name: KIT gene expression is stimulated by TFAP2A,(TFAP2B) homodimers  (Homo sapiens)


name: a ubiquinol => 2 e(-) + a ubiquinone + 2 H(+)


name: L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-alpha-D-glucosaminyl)-L-threonyl-[protein] + UDP + H(+)


name: sphinganine 1-phosphate = hexadecanal + phosphoethanolamine


name: ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA (Sus scrofa)


name: SLC9B1/C2 exchange Na+ for H+ (Gallus gallus)


name: campesine G + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+) => campesine D + reduced [NADPH--hemoprotein reductase] + O2


name: ER calcium channels open in response to activated PKA (Canis familiaris)


name: ITCH polyubiquitinates TP73 (Bos taurus)


name: low-affinity tryptophan transmembrane transporter activity


name: [(1'E)-3'-hydroxy-3',7'-dimethylocta-1',6'-dien-1'-yl]-quinolinone B + diphosphate => yaequinolone E + dimethylallyl diphosphate + H2O


name: 3-oxochol-4-en-22-oyl-CoA + AMP + diphosphate => 3-oxochol-4-en-22-oate + ATP + CoA


name: N-acetyl-L-leucine + CoA + H(+) => L-leucine + acetyl-CoA


name: NOTCH3 coactivator complex binds HES1 gene promoter (Homo sapiens)


name: Gi activation by P2Y purinoceptor 12 (Homo sapiens)


name: TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex (Bos taurus)


name: calcitriol + UDP-alpha-D-glucuronate = calcitriol 25-O-(beta-D-glucuronide) + UDP + H(+)


name: TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane (Homo sapiens)


name: 5,10-methylenetetrahydromethanopterin + oxidized coenzyme F420-(gamma-L-Glu)(n) + 2 H(+) <=> 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420-(gamma-L-Glu)(n)


name: (S)-3-hydroxybutanoate(out) + H(+)(out) = (S)-3-hydroxybutanoate(in) + H(+)(in)


name: (R)-nicotine + A + H2O = (R)-6-hydroxynicotine + AH2


name: L-asparagine transmembrane transporter activity


name: arsenite + 3 glutathione + H(+) => arsenic triglutathione + 3 H2O


name: Translocation of active Cdc25C to the nucleus (Bos taurus)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Xenopus tropicalis)


name: 8,9-EET is hydrolysed to 8.9-DHET by EPHX2 (Bos taurus)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O = (1S,4E,8E,12E)-2,2,5,9,13-pentamethylcyclopentadeca-4,8,12-trien-1-ol + diphosphate


name: dGMP + chloride + 2-oxoglutarate + O2 + H(+) <=> 2'-Cl-dGMP + succinate + CO2 + H2O


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Xenopus tropicalis)


name: 3-hydroxybenzoate + AH2 + O2 = 2,3-dihydroxybenzoate + A + H2O


name: DHI and DHICA polymerize forming eumelanin (Bos taurus)


name: Chondroitin polymerase complex transfers GlcA to CS chain (Mus musculus)


name: N-glycoloylneuraminate 9-phosphate + H2O = N-glycoloylneuraminate + phosphate


name: L-tryptophyl-[protein] + (2E,6E)-farnesyl diphosphate => (2S,3R)-3-farnesyl-2,3-dihydro-2,N(alpha)-cyclo-L-tryptophyl-[protein] + diphosphate


name: Activated JAK1 binds RAF1 (Rattus norvegicus)


name: Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Danio rerio)


name: D-ribono-1,4-lactone + NADH + H(+) => D-ribose + NAD(+)


name: 4-guanidinobutanamide + H2O = 4-guanidinobutanoate + NH4(+)


name: PAK2 phosphorylates myosin regulatory light chain (MRLC) (Sus scrofa)


name: L-prolyl-tRNA(Pro) + AMP + diphosphate => tRNA(Pro) + L-proline + ATP


name: LIG1 binds APEX1 and PCNA at SSB (Caenorhabditis elegans)


name: Phosphorylation of AKT1 on serine-473 in response to reactive oxygen species (Danio rerio)


name: (S,S)-2-(9Z-octadecenoyl)-sn-glycero-1-phospho-(2'-(9Z-octadecenoyl)-1'-sn-glycerol) + H2O = (S,S)-2-(9Z-octadecenoyl)-sn-glycero-1-phospho-(1'-sn-glycerol) + (9Z)-octadecenoate + H(+)


name: DPP4(39-766) hydrolyzes Glucagon-like Peptide-1 (GLP-1) (Canis familiaris)


name: octanal + 2 Fe(II)-[cytochrome c] + 2 H(+) => octan-1-ol + 2 Fe(III)-[cytochrome c]


name: 6-phospho-N-acetyl-beta-D-muramate-(1->4)-N-acetyl-D-glucosamine + H2O <=> N-acetyl-D-muramate 6-phosphate + N-acetyl-D-glucosamine


name: (S)-2-hydroxyoctadecanoate + NAD(+) = 2-oxooctadecanoate + NADH + H(+)


name: L-cysteine + L-arginine <=> N-amidino-L-cysteine + L-ornithine


name: Endocytosis of Ca impermeable AMPA receptors (Drosophila melanogaster)


name: a ribonucleoside 5'-diphosphate + ADP => a ribonucleoside 5'-triphosphate + AMP


name: [protein]-C-terminal O-(ADP-D-ribosyl)-glycine + nicotinamide => [protein]-C-terminal glycine + NAD(+)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CTP + H(+) = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate


name: Interaction of IRF9 with p-STAT2:p-STAT1 (Rattus norvegicus)


name: SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix (Canis familiaris)


name: GGPS1 hexamer transfers IPPP to DMAPP (Drosophila melanogaster)


name: hexadecane-1,16-diol + O2 => hydroxyhexadecanal + H2O2


name: p-Y693-STAT4 dimer translocates to the nucleus (Bos taurus)


name: candesartan + UDP-alpha-D-glucuronate = candesartan-2-N-beta-D-glucuronide + UDP


name: 5,6,7,8-tetrahydropteridine + NAD(+) => 6,7-dihydropteridine + NADH + H(+)


name: BIL dissociates from GSTA1, FABP1 (Canis familiaris)


name: MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG (Saccharomyces cerevisiae)


name: adenosine(645) in 25S rRNA + S-adenosyl-L-methionine = N(1)-methyladenosine(645) in 25S rRNA + S-adenosyl-L-homocysteine + H(+)


name: biliverdin IXalpha(in) + ATP + H2O = biliverdin IXalpha(out) + ADP + phosphate + H(+)


name: 1-phenylethanol + NAD(+) <=> acetophenone + NADH + H(+)


name: D-galactose + O2 = D-galacto-hexodialdose + H2O2


name: Phosphorylated ERF translocates to the cytosol (Danio rerio)


name: NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Rattus norvegicus)


name: 1,6-anhydro-N-acetyl-beta-muramate + ATP + H2O = N-acetyl-D-muramate 6-phosphate + ADP + H(+)


name: a 1-acylglycerone 3-phosphate + hexadecan-1-ol <=> 1-O-hexadecylglycerone 3-phosphate + a fatty acid + H(+)


name: L-aspartate 4-semialdehyde + agmatine + NADPH + H(+) => N(1)-[(S)-3-amino-3-carboxypropyl]agmatine + NADP(+) + H2O


name: Formation of the CTF18 complex (Gallus gallus)


name: (R)-noradrenaline + S-adenosyl-L-methionine => (R)-normetanephrine + S-adenosyl-L-homocysteine + H(+)


name: Collagen type I binds integrin alpha11beta1 (Mus musculus)


name: p-Y705,S727-STAT3 dimerizes (Caenorhabditis elegans)


name: Formation of the Spliceosomal B complex (Rattus norvegicus)


name: D-glucosamine + ADP <=> D-glucosamine 6-phosphate + AMP + H(+)


name: alpha-secretase cleaves the p75NTR extracellular domain (Mus musculus)


name: chlorophyll a + 2 H(+) <=> pheophytin a + Mg(2+)


name: GNLY binds the bacterial cell surface in the phagosome (Gallus gallus)


name: PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Saccharomyces cerevisiae)


name: 16beta,17beta-estriol + UDP-alpha-D-glucuronate => 16beta,17beta-estriol 3-O-(beta-D-glucuronate) + UDP + H(+)


name: PDPK1 phosphorylates AKT at T308 (Homo sapiens)


name: 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)-cholecalciferol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) <=> 1alpha,25-dihydroxy-2beta-(1,3-dihydroxypropoxy)-cholecalciferol + 2 Fe(III)-[cytochrome b5] + H2O


name: Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Homo sapiens)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate <=> 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + CDP-choline = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: 2-heptyl-3-hydroxy-4(1H)-quinolone + O2 => N-octanoylanthranilate + CO + H(+)


name: 3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide a <=> 3-deacetyl-3-vinylbacteriochlorophyllide a + H2O


name: PFKFKB dimer phosphorylates Fru(6)P (Bos taurus)


name: 2-methoxy-5-methyl-6-all-trans-decaprenyl-1,4-benzoquinone + NADH + O2 => 3-demethylubiquinone-10 + NAD(+) + H2O


name: 4 Na(+)(in) + ATP + H2O => 4 Na(+)(out) + ADP + phosphate + H(+)


name: DGAT2 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex (Homo sapiens)


name: COQ4 decarboxylates MHDB (Dictyostelium discoideum)


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A (E. coli) + holo-[ACP] => alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(dodecanoyl)-lipid IVA (E. coli) + tetradecanoyl-[ACP]


name: Glycosylated alpha-DAG1 localizes to Golgi (Mus musculus)


name: PTPN3 dephosphorylates EPS15 (Gallus gallus)


name: ML-236C carboxylate + H2O => 3alpha-hydroxy-3,5-dihydro-ML-236C carboxylate


name: CYP4V2 omega-hydroxylates DHA to HDoHE (Rattus norvegicus)


name: Complement factor I complex formation (Homo sapiens)


name: Activation of proMMP8 (Canis familiaris)


name: ZNF598 K63 polyubiquitinates RPS10 (eS10) and RPS20 (uS10) of the 40S ribosomal subunit (Saccharomyces cerevisiae)


name: Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: an N-acylsphing-4-enine + D-galactose => a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O


name: butan-2-one + NADP(+) = but-3-en-2-one + NADPH + H(+)


name: SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Canis familiaris)


name: 5-methylaminomethyl-S-(2E)-geranyl-thiouridine(34) in tRNA + selenophosphate + H(+) <=> 5-methylaminomethyl-2-(Se-phospho)selenouridine(34) in tRNA + (2E)-thiogeraniol


name: proton-transporting ATP synthase activity, rotational mechanism


name: MLH1:PMS2 makes single strand incision near 1-2 base mismatch (Canis familiaris)


name: Decreased Calcium-sensing Receptor Sensitivity


name: PTGFR binds PTGFR agonists (Rattus norvegicus)


name: a quinone + succinate = fumarate + a quinol


name: Collagen type I degradation by MMP1,2,8,13, PRSS2 (Bos taurus)


name: UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin (Gallus gallus)


name: a neolactoside nLc4Cer(d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + CMP + H(+)


name: The SHC1:SHIP1 complex is stabilized by GRB2 (Canis familiaris)


name: indole-3-pyruvate + S-adenosyl-L-methionine => (R)-3-(indol-3-yl)-2-oxobutanoate + S-adenosyl-L-homocysteine + H(+)


name: p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Homo sapiens)


name: Active FLT3 binds to ABL2 (Mus musculus)


name: D-ribulose 5-phosphate + L-tryptophan <=> (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + hydroxyacetone + formaldehyde + phosphate + H2O + H(+)


name: 1-decanoylglycerol + (9Z)-octadecenoyl-CoA = 1-decanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: L-glutamate + ATP + NADPH + H(+) <=> L-glutamate 5-semialdehyde + ADP + phosphate + NADP(+)


name: L-rhamnono-1,4-lactone + NADPH + H(+) => L-rhamnofuranose + NADP(+)


name: an N-acylsphing-4-enine + ATP = an N-acylsphing-4-enine 1-phosphate + ADP + H(+)


name: Activated FGFR3:pFRS binds GRB2:SOS1 (Canis familiaris)


name: Salvage - Sepiapterin is reduced to q-BH2 (Sus scrofa)


name: AKT1 E17K mutant phosphorylates CHUK (IKKalpha) (Homo sapiens)


name: Interleukin-1 family are secreted (Homo sapiens)


name: 5-hydroxyxanthotoxin + S-adenosyl-L-methionine <=> isopimpinellin + S-adenosyl-L-homocysteine


name: Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)


name: chlorate(in) + 2 Na(+)(in) => chlorate(out) + 2 Na(+)(out)


name: 2-hydroxy-2-methylbutanenitrile + NADP(+) + H2O => 2-methylbutyronitrile + NADPH + O2 + H(+)


name: Activation of alpha-linolenic acid to alpha-linolenoyl-CoA (Sus scrofa)


name: (R)-pantoate + NAD(+) => 2-dehydropantoate + NADH + H(+)


name: NR3C1 binds NR3C1 agonists (Mus musculus)


name: (9Z)-octadecenoate + ATP + CoA <=> (9Z)-octadecenoyl-CoA + AMP + diphosphate


name: (R)-pantothenate(out) + Na(+)(out) => (R)-pantothenate(in) + Na(+)(in)


name: (Z)-4-methylsulfanylbutyl-N-(sulfonatooxy)methanimidothioate <=> 5-(methylsulfanyl)pentanenitrile + sulfur + sulfate + H(+)


name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid (Homo sapiens)


name: 2,6-dichlorohydroquinone + FADH2 + O2 = 2-chloro-6-hydroxy-1,4-benzoquinone + FAD + chloride + H2O + 2 H(+)


name: 5-hydroxymethyluracil + succinate + CO2 => thymine + 2-oxoglutarate + O2


name: 11,12-EET is hydrolysed to 11,12-DHET by EPHX2 (Sus scrofa)


name: GMPS dimer transforms 6TXMP to 6TGMP (Rattus norvegicus)


name: 3,6,7,9-tetrahydroxy-3-methyl-2,3-dihydro-1H-naphtho[2,1-b]pyran-1-one + NADPH + O2 + H(+) => 2,3,4,7,9-pentahydroxy-6-methyl-1H-phenalen-1-one + NADP(+) + 2 H2O


name: 3,3-dimethylbutan-2-one + hydrogen cyanide <=> (2S)-2-hydroxy-2-methyl-3,3-dimethylbutanenitrile


name: L-quinate + (E)-caffeoyl-CoA = chlorogenate + CoA


name: CD28 homodimer binds B7-1 homodimer (Gallus gallus)


name: "lytic cellulose monooxygenase (C1-hydroxylating)"


name: SIRT5 deacetylates Cytochrome C (Rattus norvegicus)


name: UGTs glucuronate APAP to APAP-GlcA (Rattus norvegicus)


name: glycocholate(out) + glutarate(in) = glycocholate(in) + glutarate(out)


name: a 1,N(2)-etheno-2'-deoxyguanosine in single-stranded DNA + 2-oxoglutarate + O2 + H2O => a 2'-deoxyguanosine in single-stranded DNA + glyoxal + succinate + CO2


name: Hh-Npp binds CDON and PTCH (Mus musculus)


name: dehydroepiandrosterone 3-sulfate + H2O <=> 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)


name: ciliary neurotrophic factor receptor activity


name: Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) (Homo sapiens)


name: sartorypyrone D + acetyl-CoA = sartorypyrone A + CoA


name: HNP1-4 are stored in primary neutrophil granules (Mus musculus)


name: nonan-1-ol + hexadecanoyl-CoA = nonyl hexadecanoate + CoA


name: hexan-1-ol + octanoyl-CoA <=> hexyl octanoate + CoA


name: ATM phosphorylates TTC5 (Rattus norvegicus)


name: GAPDH tetramers reduce 1,3BPG to GA3P (Sus scrofa)


name: Caspase-mediated cleavage of TJP1 (Canis familiaris)


name: SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Gallus gallus)


name: PDE6 hydrolyses cGMP to GMP (Rattus norvegicus)


name: 3,8-divinyl protochlorophyllide a + 5'-deoxyadenosine + L-methionine + 2 H(+) => Mg-13(1)-oxoprotoporphyrin 13-monomethyl ester + S-adenosyl-L-methionine


name: (25R)-3beta-hydroxy-5-cholesten-26-al + 2 oxidized [adrenodoxin] + 2 H2O => (25R)-cholest-5-ene-3beta,26-diol + 2 reduced [adrenodoxin] + O2 + 2 H(+)


name: PA is converted to CDP-DAG by CDS1 (Caenorhabditis elegans)


name: anserine + H2O = N(pros)-methyl-L-histidine + beta-alanine


name: I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol (Danio rerio)


name: an N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine => an N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+)