(-)-tabersonine + reduced [NADPH--hemoprotein reductase] + O2 => 16-hydroxytabersonine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
(-)-tabersonine + reduced [nadph--hemoprotein reductase] + o2 => 16-hydroxytabersonine + oxidized [nadph--hemoprotein reductase] + h2o + h(+)