inositol-1,4,5-trisphosphate 3-kinase activity
inositol-1,4,5-trisphosphate 3-kinase activity
Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + H+.