guanosine(2445) in 23S rRNA + S-adenosyl-L-methionine <=> N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine + H(+)
guanosine(2445) in 23s rrna + s-adenosyl-l-methionine <=> n(2)-methylguanosine(2445) in 23s rrna + s-adenosyl-l-homocysteine + h(+)