quinine + reduced [NADPH--hemoprotein reductase] + O2 <=> 3-hydroxyquinine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
quinine + reduced [nadph--hemoprotein reductase] + o2 <=> 3-hydroxyquinine + oxidized [nadph--hemoprotein reductase] + h2o + h(+)