(2E,11Z,14Z,17Z,20Z)-hexacosapentaenoyl-CoA + NADPH + H(+) <=> (11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + NADP(+)
(2e,11z,14z,17z,20z)-hexacosapentaenoyl-coa + nadph + h(+) <=> (11z,14z,17z,20z)-hexacosatetraenoyl-coa + nadp(+)