adenosine(22) in tRNA + S-adenosyl-L-methionine <=> N(1)-methyladenosine(22) in tRNA + S-adenosyl-L-homocysteine + H(+)
adenosine(22) in trna + s-adenosyl-l-methionine <=> n(1)-methyladenosine(22) in trna + s-adenosyl-l-homocysteine + h(+)