(S)-2,3-epoxysqualene + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => squalene + reduced [NADPH--hemoprotein reductase] + O2
(s)-2,3-epoxysqualene + oxidized [nadph--hemoprotein reductase] + h2o + h(+) => squalene + reduced [nadph--hemoprotein reductase] + o2