N(6)-biotinyl-L-lysyl-[protein] + n Na(+)(out) + CO2 => N(6)-carboxybiotinyl-L-lysyl-[protein] + n Na(+)(in) + H(+)
n(6)-biotinyl-l-lysyl-[protein] + n na(+)(out) + co2 => n(6)-carboxybiotinyl-l-lysyl-[protein] + n na(+)(in) + h(+)