4 (R)-2-hydroxy-3-methylbutanoate + 4 L-leucine + 4 S-adenosyl-L-methionine + 8 ATP => bassianolide + 8 AMP + 4 S-adenosyl-L-homocysteine + 8 diphosphate + 8 H(+)
4 (r)-2-hydroxy-3-methylbutanoate + 4 l-leucine + 4 s-adenosyl-l-methionine + 8 atp => bassianolide + 8 amp + 4 s-adenosyl-l-homocysteine + 8 diphosphate + 8 h(+)