4-methylamino-4-dedimethylamino-anhydrotetracycline + S-adenosyl-L-homocysteine + H(+) => 4-amino-4-dedimethylamino-anhydrotetracycline + S-adenosyl-L-methionine
4-methylamino-4-dedimethylamino-anhydrotetracycline + s-adenosyl-l-homocysteine + h(+) => 4-amino-4-dedimethylamino-anhydrotetracycline + s-adenosyl-l-methionine