12-beta-hydroxysteroid dehydrogenase (NADP+) activity
12-beta-hydroxysteroid dehydrogenase (nadp+) activity
Catalysis of the reaction: 3-alpha,7-alpha,12-beta-trihydroxy-5-beta-cholanate + NADP+ = 3-alpha,7-alpha-dihydroxy-12-oxo-5-beta-cholanate + H+ + NADPH.