(22S)-22-hydroxysitosterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => sitosterol + reduced [NADPH--hemoprotein reductase] + O2
(22s)-22-hydroxysitosterol + oxidized [nadph--hemoprotein reductase] + h2o + h(+) => sitosterol + reduced [nadph--hemoprotein reductase] + o2