18-hydroxycortisol + 2 reduced [adrenodoxin] + O2 + 2 H(+) <=> 18-oxocortisol + 2 oxidized [adrenodoxin] + 2 H2O
18-hydroxycortisol + 2 reduced [adrenodoxin] + o2 + 2 h(+) <=> 18-oxocortisol + 2 oxidized [adrenodoxin] + 2 h2o