4-O-demethylbarbatate + reduced [NADPH--hemoprotein reductase] + O2 = proatranorin II + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
4-o-demethylbarbatate + reduced [nadph--hemoprotein reductase] + o2 = proatranorin ii + oxidized [nadph--hemoprotein reductase] + h2o + h(+)