U6 snRNA 2'-O-ribose methyltransferase activity
u6 snrna 2'-o-ribose methyltransferase activity
Catalysis of the reaction: S-adenosyl-L-methionine + U6 snRNA = S-adenosyl-L-homocysteine + U6 containing a 3'-terminal 2'-O-methylnucleotide + H+.