2'-O-methylguanosine(2922) in 27S pre-rRNA + S-adenosyl-L-homocysteine + H(+) => guanosine(2922) in 27S pre-rRNA + S-adenosyl-L-methionine
2'-o-methylguanosine(2922) in 27s pre-rrna + s-adenosyl-l-homocysteine + h(+) => guanosine(2922) in 27s pre-rrna + s-adenosyl-l-methionine