eicosanoate + holo-[(phenol)carboxyphthiodiolenone synthase] + ATP <=> icosanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate
eicosanoate + holo-[(phenol)carboxyphthiodiolenone synthase] + atp <=> icosanoyl-[(phenol)carboxyphthiodiolenone synthase] + amp + diphosphate