small RNA 3'-end 2'-O-methylnucleotide + S-adenosyl-L-homocysteine + H(+) => small RNA 3'-end nucleotide + S-adenosyl-L-methionine
small rna 3'-end 2'-o-methylnucleotide + s-adenosyl-l-homocysteine + h(+) => small rna 3'-end nucleotide + s-adenosyl-l-methionine