(S)-cis-N-methylcanadine + reduced [NADPH--hemoprotein reductase] + O2 = (S)-1-hydroxy-N-methylcanadine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
(s)-cis-n-methylcanadine + reduced [nadph--hemoprotein reductase] + o2 = (s)-1-hydroxy-n-methylcanadine + oxidized [nadph--hemoprotein reductase] + h2o + h(+)