(R)-canadine + 2 NADP(+) <=> berberine + 2 NADPH + H(+)
(r)-canadine + 2 nadp(+) <=> berberine + 2 nadph + h(+)
(R)-canadine + 2 NADP(+) <=> berberine + 2 NADPH + H(+)
(r)-canadine + 2 nadp(+) <=> berberine + 2 nadph + h(+)