(S)-nicotine + reduced [NADPH--hemoprotein reductase] + O2 <=> (S)-nornicotine + formaldehyde + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
(s)-nicotine + reduced [nadph--hemoprotein reductase] + o2 <=> (s)-nornicotine + formaldehyde + oxidized [nadph--hemoprotein reductase] + h2o + h(+)
(S)-nicotine + reduced [NADPH--hemoprotein reductase] + O2 <=> (S)-nornicotine + formaldehyde + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
(s)-nicotine + reduced [nadph--hemoprotein reductase] + o2 <=> (s)-nornicotine + formaldehyde + oxidized [nadph--hemoprotein reductase] + h2o + h(+)