a (2E,4Z)-dienoyl-CoA + NADPH + H(+) <=> a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)
a (2e,4z)-dienoyl-coa + nadph + h(+) <=> a 4,5-saturated-(3e)-enoyl-coa + nadp(+)
a (2E,4Z)-dienoyl-CoA + NADPH + H(+) <=> a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)
a (2e,4z)-dienoyl-coa + nadph + h(+) <=> a 4,5-saturated-(3e)-enoyl-coa + nadp(+)