methotrexate(in) + ATP + H2O <=> methotrexate(out) + ADP + phosphate + H(+)
methotrexate(in) + atp + h2o <=> methotrexate(out) + adp + phosphate + h(+)
methotrexate(in) + ATP + H2O <=> methotrexate(out) + ADP + phosphate + H(+)
methotrexate(in) + atp + h2o <=> methotrexate(out) + adp + phosphate + h(+)