(S)-nicotine + A + H2O => (S)-6-hydroxynicotine + AH2
(s)-nicotine + a + h2o => (s)-6-hydroxynicotine + ah2
(S)-nicotine + A + H2O => (S)-6-hydroxynicotine + AH2
(s)-nicotine + a + h2o => (s)-6-hydroxynicotine + ah2