esculetin + S-adenosyl-L-methionine => scopoletin + S-adenosyl-L-homocysteine + H(+)
esculetin + s-adenosyl-l-methionine => scopoletin + s-adenosyl-l-homocysteine + h(+)
esculetin + S-adenosyl-L-methionine => scopoletin + S-adenosyl-L-homocysteine + H(+)
esculetin + s-adenosyl-l-methionine => scopoletin + s-adenosyl-l-homocysteine + h(+)