(+)-costunolide + reduced [NADPH--hemoprotein reductase] + O2 = parthenolide + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
(+)-costunolide + reduced [nadph--hemoprotein reductase] + o2 = parthenolide + oxidized [nadph--hemoprotein reductase] + h2o + h(+)
(+)-costunolide + reduced [NADPH--hemoprotein reductase] + O2 = parthenolide + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
(+)-costunolide + reduced [nadph--hemoprotein reductase] + o2 = parthenolide + oxidized [nadph--hemoprotein reductase] + h2o + h(+)