palmatine + S-adenosyl-L-homocysteine + H(+) => columbamine + S-adenosyl-L-methionine
palmatine + s-adenosyl-l-homocysteine + h(+) => columbamine + s-adenosyl-l-methionine
palmatine + S-adenosyl-L-homocysteine + H(+) => columbamine + S-adenosyl-L-methionine
palmatine + s-adenosyl-l-homocysteine + h(+) => columbamine + s-adenosyl-l-methionine