berberine + 2 NADPH + H(+) => (R)-canadine + 2 NADP(+)
berberine + 2 nadph + h(+) => (r)-canadine + 2 nadp(+)
berberine + 2 NADPH + H(+) => (R)-canadine + 2 NADP(+)
berberine + 2 nadph + h(+) => (r)-canadine + 2 nadp(+)