(3S)-hydroxy-3-methylglutaryl-[ACP] = 4-carboxy-3-methylbut-(2E)-enoyl-[ACP] + H2O
(3s)-hydroxy-3-methylglutaryl-[acp] = 4-carboxy-3-methylbut-(2e)-enoyl-[acp] + h2o
(3S)-hydroxy-3-methylglutaryl-[ACP] = 4-carboxy-3-methylbut-(2E)-enoyl-[ACP] + H2O
(3s)-hydroxy-3-methylglutaryl-[acp] = 4-carboxy-3-methylbut-(2e)-enoyl-[acp] + h2o