acetoacetyl-CoA + acetyl-CoA + H2O <=> (3S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+)
acetoacetyl-coa + acetyl-coa + h2o <=> (3s)-3-hydroxy-3-methylglutaryl-coa + coa + h(+)
acetoacetyl-CoA + acetyl-CoA + H2O <=> (3S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+)
acetoacetyl-coa + acetyl-coa + h2o <=> (3s)-3-hydroxy-3-methylglutaryl-coa + coa + h(+)