4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine => isowyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine + H(+)
4-demethylwyosine(37) in trna(phe) + s-adenosyl-l-methionine => isowyosine(37) in trna(phe) + s-adenosyl-l-homocysteine + h(+)
4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine => isowyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine + H(+)
4-demethylwyosine(37) in trna(phe) + s-adenosyl-l-methionine => isowyosine(37) in trna(phe) + s-adenosyl-l-homocysteine + h(+)