{"type": "biolink:BiologicalProcess", "ic": "67.722653756574275", "identifiers": [{"i": "GO:0099402", "l": "plant organ development", "d": ["Development of a plant organ, a multi-tissue plant structure that forms a functional unit."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0046940", "l": "nucleoside monophosphate phosphorylation", "d": ["The process of introducing one or more phosphate groups into a nucleoside monophosphate to produce a polyphosphorylated nucleoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015941", "l": "pantothenate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070953", "l": "regulation of neutrophil mediated killing of fungus", "d": ["Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a fungal cell, the directed killing of a fungal cell by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090391", "l": "granum assembly", "d": ["A process that is carried out at the cellular level which results in the assembly of a granum. A granum is a distinct stack of lamellae seen within chloroplasts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905717", "l": "positive regulation of cornification", "d": ["Any process that activates or increases the frequency, rate or extent of cornification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905182", "l": "positive regulation of urease activity", "d": ["Any process that activates or increases the frequency, rate or extent of urease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.712091546727706", "identifiers": [{"i": "GO:0072741", "l": "protein localization to cell division site", "d": ["A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900676", "l": "negative regulation of F-9775B biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of F-9775B biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007464", "l": "R3/R4 cell fate commitment", "d": ["The process in which the R3/R4 photoreceptors commit to their cell fate. R3 and R4 are paired photoreceptors which contribute the outer rhabdomeres."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000033", "l": "regulation of seed dormancy process", "d": ["Any process that modulates the frequency, rate or extent of seed dormancy process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000017", "l": "alpha-glucoside transport", "d": ["The directed movement of alpha-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019676", "l": "ammonia assimilation cycle", "d": ["The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0050933", "l": "early stripe melanocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an early stripe melanocyte (ESM). In zebrafish, ESMs develop during the first phase (2-3 weeks of development) of the larva to adult transition (2-4 weeks of development)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001800", "l": "negative regulation of type IIb hypersensitivity", "d": ["Any process that stops, prevents, or reduces the rate of type IIb hypersensitivity, a type of inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010273", "l": "detoxification of copper ion", "d": ["Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000748", "l": "positive regulation of defecation rhythm", "d": ["Any process that activates or increases the frequency, rate or extent of defecation rhythm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051658", "l": "maintenance of nucleus location", "d": ["Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000951", "l": "regulation of xyloglucan catabolic process", "d": ["Any process that modulates the frequency, rate or extent of xyloglucan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033311", "l": "chlorophyll a biosynthetic process via phytyl diphosphate", "d": ["The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate phytyl diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014005", "l": "microglia development", "d": ["The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019409", "l": "aerobic respiration, using ammonia as electron donor", "d": ["The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen; enzymatic reactions convert ammonia to hydrazine, and hydrazine to nitrite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0006611", "l": "protein export from nucleus", "d": ["The directed movement of a protein from the nucleus into the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0034196", "l": "acylglycerol transport", "d": ["The directed movement of an acylglycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An acylglycerol is any mono-, di- or triester of glycerol with (one or more) fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060892", "l": "limb basal epidermal cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an limb basal epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.316418070386277", "identifiers": [{"i": "GO:0003007", "l": "heart morphogenesis", "d": ["The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.07248459375942", "identifiers": [{"i": "GO:0002507", "l": "tolerance induction", "d": ["A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0010227", "l": "floral organ abscission", "d": ["The controlled shedding of floral organs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904566", "l": "cellular response to 1-oleoyl-sn-glycerol 3-phosphate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900709", "l": "positive regulation of tensidol A biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of tensidol A biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0150137", "l": "interleukin-37 production", "d": ["The appearance of interleukin-37 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0007315", "l": "pole plasm assembly", "d": ["Establishment of the specialized cytoplasm found at the poles of the egg. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042431", "l": "indole metabolic process", "d": ["The chemical reactions and pathways involving indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000919", "l": "cell plate assembly", "d": ["The process of assembly, maturation, and growth of the cell plate to the cell periphery in cells that divide by cell plate formation; often involves deposition of cell wall material in and around the phragmoplast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.636556273423189", "identifiers": [{"i": "GO:0050879", "l": "multicellular organismal movement", "d": ["Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051919", "l": "positive regulation of fibrinolysis", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0070459", "l": "prolactin secretion", "d": ["The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901962", "l": "S-adenosyl-L-methionine transmembrane transport", "d": ["The directed movement of S-adenosyl-L-methionine across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048206", "l": "vesicle targeting, cis-Golgi to rough endoplasmic reticulum", "d": ["The process in which vesicles are directed to specific destination membranes during transport from the cis-Golgi to the rough ER."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0001547", "l": "antral ovarian follicle growth", "d": ["Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0052150", "l": "modulation by symbiont of host apoptotic process", "d": ["Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001195", "l": "negative regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009624", "l": "response to nematode", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0090399", "l": "replicative senescence", "d": ["A cell aging process associated with the dismantling of a cell as a response to telomere shortening and/or cellular aging."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0009173", "l": "pyrimidine ribonucleoside monophosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110125", "l": "negative regulation of myotube cell migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010257", "l": "NADH dehydrogenase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an NADH dehydrogenase complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090402", "l": "oncogene-induced cell senescence", "d": ["A cellular senescence process associated with the dismantling of a cell as a response to oncogenic stress, such as the activation of the Ras oncogenic family."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019126", "l": "peptidyl-serine racemization", "d": ["The racemization of peptidyl-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021973", "l": "corticospinal neuron axon decussation", "d": ["The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed to cross the midline to the contralateral side."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902659", "l": "regulation of glucose mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of glucose mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900522", "l": "negative regulation of response to amylopectin", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to amylopectin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090272", "l": "negative regulation of fibroblast growth factor production", "d": ["Any process that decreases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0043501", "l": "skeletal muscle adaptation", "d": ["Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903014", "l": "cellular response to differentiation-inducing factor 1", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018261", "l": "peptidyl-lysine guanylylation", "d": ["The guanylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-guanosine)-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070945", "l": "neutrophil-mediated killing of gram-negative bacterium", "d": ["The directed killing of a gram-negative bacterium by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905786", "l": "positive regulation of anaphase-promoting complex-dependent catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900143", "l": "positive regulation of oligodendrocyte apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of oligodendrocyte apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071356", "l": "cellular response to tumor necrosis factor", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0071599", "l": "otic vesicle development", "d": ["The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051089", "l": "constitutive protein ectodomain proteolysis", "d": ["The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs constantly, regardless of environmental conditions or demands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904658", "l": "positive regulation of sensory perception of sweet taste", "d": ["Any process that activates or increases the frequency, rate or extent of sensory perception of sweet taste."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006683", "l": "galactosylceramide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000638", "l": "regulation of SREBP signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the SREBP signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003320", "l": "heart rudiment involution", "d": ["The inward folding of myocardial tissue derived from the right half of the heart rudiment that will form the future ventral part of the heart tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032873", "l": "negative regulation of stress-activated MAPK cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900877", "l": "nonadec-1-ene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nonadec-1-ene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000088", "l": "negative regulation of mesonephric glomerulus development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerulus development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016063", "l": "rhodopsin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099008", "l": "viral entry via permeabilization of inner membrane", "d": ["The entry of a non-enveloped virus into the cytoplasm of a host prokaryotic cell, following fusion with the outer membrane, via permeabilization of the plasma (inner) membrane. In the case of some double stranded RNA viruses of prokaryotes this occurs via interaction of a membrane-interacting component of the capsid, leading to depolarization an permeabilization of the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048211", "l": "Golgi vesicle docking", "d": ["The initial attachment of a Golgi transport vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the Golgi vesicle and the target membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098838", "l": "folate transmembrane transport", "d": ["The process in which a folic acid, or one of its derivatives (dihydrofolate, tetrahydrofolate, methylene-tetrahydrofolate or methyl-tetrahydrofolate) is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006537", "l": "glutamate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0002011", "l": "morphogenesis of an epithelial sheet", "d": ["The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001171", "l": "positive regulation of ATP biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052787", "l": "alpha-linked polysaccharide catabolism to maltopentaose", "d": ["The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltopentaose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061366", "l": "behavioral response to chemical pain", "d": ["Any process that results in a change in the behaviour of an organism as a result of a chemical pain stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046032", "l": "ADP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5'-diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016543", "l": "male courtship behavior, orientation prior to leg tapping and wing vibration", "d": ["The process during courtship, where the male orients towards a potential partner. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904757", "l": "positive regulation of gut granule assembly", "d": ["Any process that activates or increases the frequency, rate or extent of gut granule assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035321", "l": "maintenance of imaginal disc-derived wing hair orientation", "d": ["Ensuring that hairs in the imaginal disc-derived wing continue to point distally during development, following the initial establishment of wing hair polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070417", "l": "cellular response to cold", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003202", "l": "endocardial cushion to mesenchymal transition involved in cardiac skeleton development", "d": ["A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will give rise to the cardiac skeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0048515", "l": "spermatid differentiation", "d": ["The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060052", "l": "neurofilament cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising neurofilaments and their associated proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2001115", "l": "methanopterin-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a methanopterin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085014", "l": "dormancy entry of symbiont in host", "d": ["Entry into a dormant state of the symbiont within the host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0150106", "l": "regulation of protein localization to cell-cell junction", "d": ["Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904582", "l": "positive regulation of intracellular mRNA localization", "d": ["Any process that activates or increases the frequency, rate or extent of intracellular mRNA localization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.731957435863137", "identifiers": [{"i": "GO:0019637", "l": "organophosphate metabolic process", "d": ["The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0032411", "l": "positive regulation of transporter activity", "d": ["Any process that activates or increases the activity of a transporter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0009799", "l": "specification of symmetry", "d": ["The establishment of an organism's body plan or part of an organism such that a similar arrangement in form and relationship of parts around a common axis, or around each side of a plane is created."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010692", "l": "regulation of alkaline phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032673", "l": "regulation of interleukin-4 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-4 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015973", "l": "guanosine pentaphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002599", "l": "negative regulation of antigen processing and presentation of lipid antigen via MHC class Ib", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035192", "l": "nuclear cortical migration", "d": ["The symmetric outward movement of the syncytial nuclei from their positions in the ellipsoid toward the periphery of the embryo, during mitotic cycles 8 and 9. This movement results in the placement of nuclei in a uniform monolayer at the cortex of the developing embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903780", "l": "negative regulation of cardiac conduction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062171", "l": "lutein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lutein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0050686", "l": "negative regulation of mRNA processing", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905620", "l": "negative regulation of alpha-(1->3)-fucosyltransferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:1902117", "l": "positive regulation of organelle assembly", "d": ["Any process that activates or increases the frequency, rate or extent of organelle assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075069", "l": "adhesion of symbiont infection cushion to host", "d": ["The attachment of an infection cushion of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002850", "l": "negative regulation of peripheral T cell tolerance induction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral T cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042617", "l": "paclitaxel biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of paclitaxel, a tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010615", "l": "positive regulation of cardiac muscle adaptation", "d": ["Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000368", "l": "positive regulation of acrosomal vesicle exocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903133", "l": "negative regulation of tube lumen cavitation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tube lumen cavitation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900133", "l": "regulation of renin secretion into blood stream", "d": ["Any process that modulates the frequency, rate or extent of renin secretion into blood stream."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990961", "l": "xenobiotic detoxification by transmembrane export across the plasma membrane", "d": ["A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1905349", "l": "ciliary transition zone assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0051664", "l": "nuclear pore localization", "d": ["Any process in which nuclear pores are transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903405", "l": "protein localization to nuclear body", "d": ["A process in which a protein is transported to, or maintained in, a location within a nuclear body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021911", "l": "retinoic acid metabolic process in spinal cord anterior-posterior patterning", "d": ["The chemical reactions and pathways involving the synthesis and degradation of retionic acid that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904434", "l": "positive regulation of ferrous iron binding", "d": ["Any process that activates or increases the frequency, rate or extent of ferrous iron binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905842", "l": "cellular response to oxidopamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010247", "l": "detection of phosphate ion", "d": ["The series of events in which a phosphate ion stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000385", "l": "positive regulation of ectoderm development", "d": ["Any process that activates or increases the frequency, rate or extent of ectoderm development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006559", "l": "L-phenylalanine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:1903975", "l": "regulation of glial cell migration", "d": ["Any process that modulates the frequency, rate or extent of glial cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034428", "l": "nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3'", "d": ["The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900505", "l": "positive regulation of cellulosome assembly", "d": ["Any process that activates or increases the frequency, rate or extent of cellulosome assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0018315", "l": "molybdenum incorporation into molybdenum-molybdopterin complex", "d": ["The incorporation of molybdenum into a molybdenum-molybdopterin complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0016335", "l": "morphogenesis of larval imaginal disc epithelium", "d": ["The process in which the anatomical structures of a larval imaginal disc epithelium are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1902682", "l": "protein localization to pericentric heterochromatin", "d": ["A process in which a protein is transported to, or maintained in the pericentric heterochromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903552", "l": "negative regulation of extracellular exosome assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045223", "l": "regulation of CD4 production", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032643", "l": "regulation of connective tissue growth factor production", "d": ["Any process that modulates the frequency, rate, or extent of connective tissue growth factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030719", "l": "P granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of polar granules, cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060136", "l": "embryonic process involved in female pregnancy", "d": ["A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900766", "l": "emericellin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of emericellin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015937", "l": "coenzyme A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035630", "l": "bone mineralization involved in bone maturation", "d": ["The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905432", "l": "regulation of retrograde trans-synaptic signaling by neuropeptide", "d": ["Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009616", "l": "RNAi-mediated antiviral immune response", "d": ["A post-transcriptional gene silencing pathway mediated by the action of regulatory RNAs that protects against foreign organism invasion by restricting viral replication and dissemination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0061756", "l": "leukocyte adhesion to vascular endothelial cell", "d": ["The attachment of a leukocyte to vascular endothelial cell via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062177", "l": "radial spoke assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the radial spoke, a protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0060995", "l": "cell-cell signaling involved in kidney development", "d": ["Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033339", "l": "pectoral fin development", "d": ["The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051110", "l": "peptidyl-histidine uridylylation, to form peptidyl-1'-(phospho-5'-uridine)-L-histidine", "d": ["The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.000891501185137", "identifiers": [{"i": "GO:0001932", "l": "regulation of protein phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018364", "l": "peptidyl-glutamine methylation", "d": ["The addition of a methyl group to a glutamine residue in a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098768", "l": "meiotic prometaphase I", "d": ["The meiotic cell cycle phase in eukaryotes between meiotic prophase I and meiotic metaphase I. During meiotic prometaphase I, the nuclear envelope breaks down and one kinetochore forms per chromosome. Chromosomes attach to spindle microtubules and begin to move towards the metaphase plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902276", "l": "regulation of pancreatic amylase secretion", "d": ["Any process that modulates the frequency, rate or extent of pancreatic amylase secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060982", "l": "coronary artery morphogenesis", "d": ["The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009095", "l": "aromatic amino acid family biosynthetic process, prephenate pathway", "d": ["The chemical reactions and pathways resulting in the formation of phenylalanine and tyrosine from other compounds, including chorismate, via the intermediate prephenate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0042267", "l": "natural killer cell mediated cytotoxicity", "d": ["The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043640", "l": "benzoate catabolic process via hydroxylation", "d": ["The chemical reactions and pathways resulting in the breakdown of benzoate, by its hydroxylation to cis-1,2-dihydroxybenzoate followed by dehydrogenation to catechol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904708", "l": "regulation of granulosa cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of granulosa cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031564", "l": "transcription antitermination", "d": ["A positive regulation of gene expression mechanism that allows RNA polymerase to continue transcription beyond a termination site, thus allowing expression of downstream genes under specific conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.465174152298118", "identifiers": [{"i": "GO:0002065", "l": "columnar/cuboidal epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.701260003289605", "identifiers": [{"i": "GO:0071887", "l": "leukocyte apoptotic process", "d": ["Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:1904304", "l": "regulation of gastro-intestinal system smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042560", "l": "pteridine-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001034", "l": "positive regulation of double-strand break repair via nonhomologous end joining", "d": ["Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062233", "l": "F2-isoprostane catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of F2-isoprostane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045838", "l": "positive regulation of membrane potential", "d": ["Any process that activates or increases the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060730", "l": "regulation of intestinal epithelial structure maintenance", "d": ["Any process that modulates the rate, frequency, or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002537", "l": "nitric oxide production involved in inflammatory response", "d": ["The synthesis or release of nitric oxide following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0001655", "l": "urogenital system development", "d": ["The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061299", "l": "retina vasculature morphogenesis in camera-type eye", "d": ["The process in which the vasculature of the retina is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033486", "l": "delphinidin 3-O-glucoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of delphinidin 3-O-glucoside, a basic, water-soluble anthocyanin responsible for blue coloration of flowers and fruits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0042730", "l": "fibrinolysis", "d": ["A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904327", "l": "protein localization to cytosolic proteasome complex", "d": ["A process in which a protein is transported to, or maintained in, a location within a cytosolic proteasome complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0009303", "l": "rRNA transcription", "d": ["The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010759", "l": "positive regulation of macrophage chemotaxis", "d": ["Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904285", "l": "regulation of protein-pyridoxal-5-phosphate linkage", "d": ["Any process that modulates the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046205", "l": "nor-spermidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.819490397197882", "identifiers": [{"i": "GO:0031401", "l": "positive regulation of protein modification process", "d": ["Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:0072593", "l": "reactive oxygen species metabolic process", "d": ["The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016559", "l": "peroxisome fission", "d": ["The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061159", "l": "establishment of bipolar cell polarity involved in cell morphogenesis", "d": ["The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. Bipolar organization is the organization that is a mirror image along an axis from a plane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001155", "l": "negative regulation of glycolytic fermentation to ethanol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to ethanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903186", "l": "regulation of vitellogenesis", "d": ["Any process that modulates the frequency, rate or extent of vitellogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009233", "l": "menaquinone metabolic process", "d": ["The chemical reactions and pathways involving any of the menaquinones, quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904584", "l": "cellular response to polyamine macromolecule", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0034109", "l": "homotypic cell-cell adhesion", "d": ["The attachment of a cell to a second cell of the identical type via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042320", "l": "regulation of circadian sleep/wake cycle, REM sleep", "d": ["Any process that modulates the frequency, rate or extent of rapid eye movement (REM) sleep."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0033194", "l": "response to hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051904", "l": "pigment granule transport", "d": ["The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098629", "l": "trans-Golgi network membrane organization", "d": ["A process which results in the assembly, arrangement of constituent parts, or disassembly of a trans-Golgi network membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904524", "l": "negative regulation of DNA amplification", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA amplification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036271", "l": "response to methylphenidate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylphenidate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0071170", "l": "site-specific DNA replication termination", "d": ["A DNA replication termination process that takes place at a specific termination site."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032124", "l": "macronucleus organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the macronucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019467", "l": "ornithine catabolic process, by decarboxylation", "d": ["The chemical reactions and pathways resulting in the breakdown of ornithine by decarboxylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0006687", "l": "glycosphingolipid metabolic process", "d": ["The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:1902807", "l": "negative regulation of cell cycle G1/S phase transition", "d": ["Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0009438", "l": "methylglyoxal metabolic process", "d": ["The chemical reactions and pathways involving methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038001", "l": "paracrine signaling", "d": ["The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. The signaling cell and the receiving cell are usually in the vicinity of each other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006202", "l": "GMP catabolic process to guanine", "d": ["The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including guanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045345", "l": "positive regulation of MHC class I biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:1902975", "l": "mitotic DNA replication initiation", "d": ["Any DNA replication initiation involved in mitotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0061157", "l": "mRNA destabilization", "d": ["Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905625", "l": "negative regulation of L-methionine import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-methionine import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030982", "l": "adventurous gliding motility", "d": ["A process involved in the controlled movement of a bacterial cell powered by the rearward secretion of carbohydrate slime."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061221", "l": "mesonephric mesenchyme morphogenesis", "d": ["The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070807", "l": "positive regulation of phialide development", "d": ["Any process that activates or increases the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051459", "l": "regulation of corticotropin secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071371", "l": "cellular response to gonadotropin stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0034411", "l": "cell wall (1->3)-beta-D-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051057", "l": "positive regulation of small GTPase mediated signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039668", "l": "viral entry into host cell via pilus basal pore", "d": ["The uptake of a virus or viral genetic material into a host cell which occurs through retraction of the virion-bound pilus, followed by entry of the viral genome into the host cell through the pilus basal pore. Filamentous bacteriophages absorb to the tip of the F-pili and can enter the bacterial cell in this way."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0033333", "l": "fin development", "d": ["The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902769", "l": "regulation of choline O-acetyltransferase activity", "d": ["Any process that modulates the frequency, rate or extent of choline O-acetyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009450", "l": "gamma-aminobutyric acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033525", "l": "sinapate ester biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ester derivates of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.685364931984026", "identifiers": [{"i": "GO:0003010", "l": "voluntary skeletal muscle contraction", "d": ["A process in which force is generated within voluntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the voluntary skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and it is under voluntary control. Voluntary skeletal muscle is skeletal muscle that is under conscious control."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0006269", "l": "DNA replication, synthesis of RNA primer", "d": ["The synthesis of a short RNA polymer, usually 4-15 nucleotides long, using one strand of unwound DNA as a template; the RNA then serves as a primer from which DNA polymerases extend synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0048682", "l": "sprouting of injured axon", "d": ["The process involved in sprouting of an injured axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901877", "l": "negative regulation of calcium ion binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048832", "l": "specification of plant organ number", "d": ["The regionalization process that modulates the quantity of a particular type of plant organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0007274", "l": "neuromuscular synaptic transmission", "d": ["The process of synaptic transmission from a neuron to a muscle, across a synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900214", "l": "regulation of apoptotic process involved in metanephric collecting duct development", "d": ["Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902954", "l": "regulation of early endosome to recycling endosome transport", "d": ["Any process that modulates the frequency, rate or extent of early endosome to recycling endosome transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040032", "l": "post-embryonic body morphogenesis", "d": ["The process in which the anatomical structures of the post-embryonic soma are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0055075", "l": "potassium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140990", "l": "primary piRNA processing", "d": ["The process involved in converting precursor piRNAs into non-overlapping, contiguous primary piRNAs (approximately 24-30-nt piRNAs with a preference for a 5' uridine (U) via the endonucleolytic activity of cytosolic PIWI. This may include pre-piRNA maturation of 3' ends by trimming and 2'-O-methylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:1901160", "l": "primary amino compound metabolic process", "d": ["The chemical reactions and pathways involving primary amino compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905758", "l": "positive regulation of primary cell septum biogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of primary cell septum biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902981", "l": "synthesis of RNA primer involved in mitotic DNA replication", "d": ["Any synthesis of RNA primer involved in mitotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051915", "l": "induction of synaptic plasticity by chemical substance", "d": ["The process in which a chemical substance activates synaptic plasticity, the ability of synapses to change as circumstances require."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060329", "l": "cytoplasmic actin-based contraction involved in rearward cell motility", "d": ["The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the rear of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:2001242", "l": "regulation of intrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140969", "l": "determination of lung left/right asymmetry", "d": ["Determination of the asymmetric location of the lungs with respect to the left and right halves of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060889", "l": "limb basal epidermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal basal cell. A epidermal basal cell cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into more specialized cell of the limb epidermis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0080188", "l": "gene silencing by RNA-directed DNA methylation", "d": ["A small RNA-based gene silencing process in which small interfering RNAs (siRNAs) guide DNA methylation to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription. In general this process consists of three phases: biogenesis of siRNAs, scaffold RNA production, and the formation of the guiding complex that recruits de novo DNA methyltransferases to the target loci. Transposable elements are silenced by this mechanism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032964", "l": "collagen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001937", "l": "negative regulation of endothelial cell proliferation", "d": ["Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0080050", "l": "regulation of seed development", "d": ["Any process that modulates the frequency, rate or extent of seed development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "51.930068411490673", "identifiers": [{"i": "GO:0043207", "l": "response to external biotic stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071316", "l": "cellular response to nicotine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.468544520863134", "identifiers": [{"i": "GO:0048857", "l": "neural nucleus development", "d": ["The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034184", "l": "positive regulation of maintenance of mitotic sister chromatid cohesion", "d": ["Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904807", "l": "negative regulation of protein oxidation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein oxidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007430", "l": "terminal branching, open tracheal system", "d": ["Formation of terminal branches in the open tracheal system. These are long cytoplasmic extensions that form fine tubules that transport oxygen directly to the tissues. An example of the process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001869", "l": "negative regulation of complement activation, lectin pathway", "d": ["Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0060206", "l": "estrous cycle phase", "d": ["The progression of physiological phases, occurring in the endometrium during the estrous cycle that recur at regular intervals during the reproductive years. The estrous cycle is an ovulation cycle where the endometrium is resorbed if pregnancy does not occur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042994", "l": "cytoplasmic sequestering of transcription factor", "d": ["The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0040014", "l": "regulation of multicellular organism growth", "d": ["Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097359", "l": "UDP-glucosylation", "d": ["The covalent attachment of a UDP-glucose residue to a substrate molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072389", "l": "flavin adenine dinucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043610", "l": "regulation of carbohydrate utilization", "d": ["Any process that modulates the frequency, rate or extent of carbohydrate utilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042351", "l": "'de novo' GDP-L-fucose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033331", "l": "ent-kaurene metabolic process", "d": ["The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051485", "l": "terpenoid biosynthetic process, mevalonate-dependent", "d": ["The chemical reactions and pathways resulting in the formation of terpenoids via isopentenyl diphosphate, synthesized by the mevalonate pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-dependent terpenoid biosynthesis, acetate, in the form of acetyl-CoA, is converted to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071452", "l": "cellular response to singlet oxygen", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070802", "l": "regulation of metula development", "d": ["Any process that modulates the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075506", "l": "entry of viral genome into host nucleus through nuclear pore complex via importin", "d": ["Viral penetration into the host nucleus where the viral genome passes through the nuclear pore complex (NPC) using the cellular importin transport machinery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.905555711669919", "identifiers": [{"i": "GO:0045834", "l": "positive regulation of lipid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904836", "l": "facioacoustic ganglion morphogenesis", "d": ["The developmental process by which an acoustico-facial VII-VIII ganglion complex is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071724", "l": "response to diacyl bacterial lipopeptide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.466824939696082", "identifiers": [{"i": "GO:0007281", "l": "germ cell development", "d": ["The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905373", "l": "ceramide phosphoethanolamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ceramide phosphoethanolamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090298", "l": "negative regulation of mitochondrial DNA replication", "d": ["Any process that decreases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0030810", "l": "positive regulation of nucleotide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051040", "l": "regulation of calcium-independent cell-cell adhesion", "d": ["Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0050995", "l": "negative regulation of lipid catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030995", "l": "cell septum edging catabolic process", "d": ["The chemical reactions and pathways resulting in the dissolution of the septum edging during cell separation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019248", "l": "D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde", "d": ["The chemical reactions and pathways resulting in the formation of D-lactate from methylglyoxal, via the intermediate (R)-lactaldehyde."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060659", "l": "nipple sheath formation", "d": ["The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. This process begins with a circular ingrowth of the epidermis around the region of the mammary sprout. It ends before the region begins to elevate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903249", "l": "negative regulation of citrulline biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of citrulline biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000317", "l": "negative regulation of T-helper 17 type immune response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 type immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901418", "l": "positive regulation of response to ethanol", "d": ["Any process that activates or increases the frequency, rate or extent of response to ethanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034659", "l": "isopropylmalate transport", "d": ["The directed movement of isopropylmalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032832", "l": "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response", "d": ["Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006651", "l": "diacylglycerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018180", "l": "protein desulfurization", "d": ["The removal of a sulfur group from a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904965", "l": "regulation of vitamin E biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of vitamin E biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032601", "l": "connective tissue growth factor production", "d": ["The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904858", "l": "negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0006516", "l": "glycoprotein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0150104", "l": "transport across blood-brain barrier", "d": ["The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0019072", "l": "viral genome packaging", "d": ["The encapsulation of the viral genome within the capsid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035470", "l": "positive regulation of vascular wound healing", "d": ["Any process that increases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033562", "l": "co-transcriptional gene silencing by RNA interference machinery", "d": ["A process in which the RNAi machinery mediates the degradation of nascent transcripts in association with chromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0061844", "l": "antimicrobial humoral immune response mediated by antimicrobial peptide", "d": ["An immune response against microbes mediated by anti-microbial peptides in body fluid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000394", "l": "positive regulation of lamellipodium morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of lamellipodium morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990280", "l": "RNA localization to chromatin", "d": ["A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090167", "l": "Golgi distribution to daughter cells", "d": ["Any process in which disassembled Golgi vesicles are localized into daughter cells upon cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0070784", "l": "regulation of growth of unicellular organism as a thread of attached cells", "d": ["Any process that modulates the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0051784", "l": "negative regulation of nuclear division", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902821", "l": "1-undecene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 1-undecene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010387", "l": "COP9 signalosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a COP9 signalosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0070585", "l": "protein localization to mitochondrion", "d": ["A process in which a protein is transported to, or maintained in, a location within the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0180012", "l": "co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway", "d": ["Any process involved in transcription termination-coupled  3' processing of RNA polymerase II RNA transcripts by 3' end cleavage  and addition of a poly(A) tail. This pathway is required for the maturation of primary protein-encoding transcripts into functional RNAs that can be exported from the nucleus and translated in the cytoplasm, but is also required for polyadenylation-dependent decay."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903165", "l": "response to polycyclic arene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018962", "l": "3-phenylpropionate metabolic process", "d": ["The chemical reactions and pathways involving 3-phenylpropionate, the anion of phenylpropanoic acid. It is produced from putrefaction of proteins in soil or breakdown of several constituents of plants, such as lignin, various oils and resins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901917", "l": "regulation of exoribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of exoribonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0055034", "l": "Bolwig's organ development", "d": ["The process whose specific outcome is the progression of the Bolwig's organ over time, from its formation to the mature structure. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:2000769", "l": "regulation of establishment or maintenance of cell polarity regulating cell shape", "d": ["Any process that modulates the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0006925", "l": "inflammatory cell apoptotic process", "d": ["Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072452", "l": "response to G2 transition size control checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of G2/M transition size control checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009729", "l": "detection of brassinosteroid stimulus", "d": ["The series of events in which a brassinosteroid stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0060512", "l": "prostate gland morphogenesis", "d": ["The process in which the anatomical structures of a prostate gland are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.768275768238951", "identifiers": [{"i": "GO:0006790", "l": "sulfur compound metabolic process", "d": ["The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905604", "l": "negative regulation of blood-brain barrier permeability", "d": ["Any process that decreases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019926", "l": "peptidyl-tryptophan oxidation to tryptophyl quinone", "d": ["The oxidation of peptidyl-tryptophan to form tryptophan-6,7-dione, otherwise known as tryptophyl quinone, which is further modified by cross-linking to either tryptophan or cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000937", "l": "negative regulation of cellotriose catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044720", "l": "negative regulation of imaginal disc-derived wing size", "d": ["Any process that reduces the size of an imaginal disc-derived wing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000271", "l": "positive regulation of fibroblast apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032805", "l": "positive regulation of low-density lipoprotein particle receptor catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0050769", "l": "positive regulation of neurogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036165", "l": "invasive growth in response to heat", "d": ["The growth of colonies in filamentous chains of cells as a result of an increase in temperature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "47.623717844629169", "identifiers": [{"i": "GO:0010467", "l": "gene expression", "d": ["The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, translation and maturation for protein-coding genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042841", "l": "D-glucuronate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-glucuronate, the D-enantiomer of glucuronate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901059", "l": "p-hydroxyphenyl lignin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of p-hydroxyphenyl lignin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009779", "l": "noncyclic photosynthetic phosphorylation", "d": ["A photosynthetic phosphorylation process in which ATP synthesis is linked to the transport of electrons from water to NADP+ with the production of NADPH and dioxygen (O2). Involves photosystem I and photosystem II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0055003", "l": "cardiac myofibril assembly", "d": ["The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905495", "l": "positive regulation of G-quadruplex DNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002257", "l": "negative regulation of kinin cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the kinin cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021541", "l": "ammon gyrus development", "d": ["The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. The ammon gyrus, often subdivided into the CA1 and CA3 regions, is one of the two interlocking gyri of the hippocampus that is rich in large pyramidal neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902389", "l": "ceramide 1-phosphate transport", "d": ["The directed movement of a ceramide 1-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.46572637595327", "identifiers": [{"i": "GO:0044237", "l": "cellular metabolic process", "d": ["The chemical reactions and pathways by which individual cells transform chemical substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000788", "l": "negative regulation of venous endothelial cell fate commitment", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of venous endothelial cell fate commitment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000661", "l": "positive regulation of interleukin-1-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-1-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0021955", "l": "central nervous system neuron axonogenesis", "d": ["Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900652", "l": "regulation of demethylkotanin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of demethylkotanin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903195", "l": "regulation of L-dopa biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of L-dopa biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0086091", "l": "regulation of heart rate by cardiac conduction", "d": ["A cardiac conduction process that modulates the frequency or rate of heart contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018882", "l": "(+)-camphor metabolic process", "d": ["The chemical reactions and pathways involving (+)-camphor, a bicyclic monoterpene ketone which is one of the major components in the leaves of common sage. Camphor exists in two enantiomers, but the (+)-isomer is more widely distributed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033504", "l": "floor plate development", "d": ["The progression of the floor plate over time from its initial formation until its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0014841", "l": "skeletal muscle satellite cell proliferation", "d": ["The multiplication or reproduction of satellite cells, resulting in the expansion of the cell population. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140374", "l": "antiviral innate immune response", "d": ["A defense response against viruses mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038004", "l": "epidermal growth factor receptor ligand maturation", "d": ["Any process leading to the attainment of the full functional capacity of a ligand for an epidermal growth factor receptor. The ligand is functional when it can bind to and activate an epidermal growth factor receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000089", "l": "mitotic metaphase", "d": ["The cell cycle phase, following prophase, during which chromosomes become aligned on the equatorial plate of the cell as part of a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032903", "l": "regulation of nerve growth factor production", "d": ["Any process that modulates the frequency, rate, or extent of production of nerve growth factor (NGF)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002207", "l": "gene conversion of immunoglobulin genes involved in immune response", "d": ["The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion following the induction of and contributing to an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.569439710577498", "identifiers": [{"i": "GO:0043244", "l": "regulation of protein-containing complex disassembly", "d": ["Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0086049", "l": "membrane repolarization during AV node cell action potential", "d": ["The process in which ions are transported across a membrane such that the AV node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019491", "l": "ectoine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0042572", "l": "retinol metabolic process", "d": ["The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1903051", "l": "negative regulation of proteolysis involved in protein catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.725591100956891", "identifiers": [{"i": "GO:0016571", "l": "histone methylation", "d": ["The modification of histones by addition of methyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001276", "l": "regulation of leucine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of leucine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070781", "l": "response to biotin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903384", "l": "negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0042219", "l": "cellular modified amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0075015", "l": "formation of infection structure", "d": ["The formation of a symbiont structure that serves to infect its host organism. It includes physiological, developmental, and morphological changes of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033480", "l": "UDP-D-galacturonate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000357", "l": "negative regulation of kidney smooth muscle cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of kidney smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000583", "l": "regulation of platelet-derived growth factor receptor-alpha signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900792", "l": "shamixanthone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of shamixanthone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0046635", "l": "positive regulation of alpha-beta T cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of alpha-beta T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903808", "l": "L-tyrosine import across plasma membrane", "d": ["The directed movement of L-tyrosine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990535", "l": "neuron projection maintenance", "d": ["The organization process that preserves a neuron projection in a stable functional or structural state. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060585", "l": "positive regulation of prostaglandin-endoperoxide synthase activity", "d": ["Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032232", "l": "negative regulation of actin filament bundle assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140722", "l": "mycophenolic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mycophenolic acid (MPA). MPA is the first isolated antibiotic natural product in the world obtained from a culture of Penicillium brevicompactum in 1893."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021748", "l": "dorsal cochlear nucleus development", "d": ["The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141009", "l": "piRNA-mediated retrotransposon silencing by mRNA destabilization", "d": ["A retrotransposon silencing mechanism in which mRNAs transcribed from transposons are targeted for degradation by a piRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045613", "l": "regulation of plasmatocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of plasmatocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901442", "l": "regulation of response to furfural", "d": ["Any process that modulates the frequency, rate or extent of response to furfural."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.505763639973935", "identifiers": [{"i": "GO:0002449", "l": "lymphocyte mediated immunity", "d": ["Any process involved in the carrying out of an immune response by a lymphocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900896", "l": "regulation of heptadecane biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of heptadecane biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044618", "l": "modulation of relaxation of uterine smooth muscle in another organism", "d": ["The process in which an organism effects a change in the relaxation of smooth muscle in the uterus of a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150140", "l": "regulation of CD86 production", "d": ["Any process that modulates the frequency, rate or extent of CD86 biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021524", "l": "visceral motor neuron differentiation", "d": ["The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of visceral motor neurons. Visceral motor neurons innervate glandular targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070234", "l": "positive regulation of T cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032905", "l": "transforming growth factor beta1 production", "d": ["The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:1901989", "l": "positive regulation of cell cycle phase transition", "d": ["Any process that activates or increases the frequency, rate or extent of cell cycle phase transition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904101", "l": "response to acadesine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0043087", "l": "regulation of GTPase activity", "d": ["Any process that modulates the rate of GTP hydrolysis by a GTPase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002243", "l": "detection of parasitic plant", "d": ["The series of events in which a stimulus from a parasitic plant is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002553", "l": "histamine secretion by mast cell", "d": ["The regulated release of histamine by a mast cell or group of mast cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015764", "l": "N-acetylglucosamine transport", "d": ["The directed movement of N-acetylglucosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036098", "l": "male germ-line stem cell population maintenance", "d": ["The process by which an organism or tissue maintains a population of male germ-line stem cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902980", "l": "synthesis of RNA primer involved in premeiotic DNA replication", "d": ["Any synthesis of RNA primer involved in meiotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045728", "l": "respiratory burst after phagocytosis", "d": ["A phase of elevated metabolic activity, during which oxygen consumption increases, that occurs in neutrophils, monocytes, and macrophages shortly after phagocytosing material. An enhanced uptake of oxygen leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, which play a part in microbiocidal activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060478", "l": "acrosomal vesicle exocytosis", "d": ["The calcium ion regulated exocytosis which results in fusion of the acrosomal vesicle with the plasma membrane of the sperm as part of the acrosome reaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900113", "l": "negative regulation of histone H3-K9 trimethylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 trimethylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904782", "l": "negative regulation of NMDA glutamate receptor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of NMDA glutamate receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009715", "l": "chalcone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chalcone, phenyl steryl ketone or its hydroxylated derivatives."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032382", "l": "positive regulation of intracellular sterol transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of sterols within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901581", "l": "negative regulation of telomeric RNA transcription from RNA pol II promoter", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046741", "l": "transport of virus in host, tissue to tissue", "d": ["The transport of a virus between tissues in a multicellular organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060476", "l": "protein localization involved in acrosome reaction", "d": ["The actin-based process in which a protein is transported to, or maintained in, a specific location in the sperm as part of the acrosome reaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901903", "l": "tyrocidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tyrocidine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0044347", "l": "cell wall polysaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cell wall polysaccharides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032539", "l": "negative regulation of host-seeking behavior", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of any behavior associated with finding a host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0110020", "l": "regulation of actomyosin structure organization", "d": ["Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1903260", "l": "protein localization to mating projection tip", "d": ["A process in which a protein is transported to, or maintained in, a location within a mating projection tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061147", "l": "endocardial endothelium development", "d": ["The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021878", "l": "forebrain astrocyte fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into an astrocyte that resides in the forebrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021501", "l": "prechordal plate formation", "d": ["The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032728", "l": "positive regulation of interferon-beta production", "d": ["Any process that activates or increases the frequency, rate, or extent of interferon-beta production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018015", "l": "N-terminal peptidyl-phenylalanine methylation", "d": ["The methylation of the N-terminal phenylalanine of proteins to form the derivative N-methyl-L-phenylalanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000448", "l": "positive regulation of macrophage migration inhibitory factor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061163", "l": "endoplasmic reticulum polarization", "d": ["The endoplasmic reticulum organization process that results in the structure of the endoplasmic reticulum being oriented in the cell. Endoplasmic reticulum polarization serves as a mechanism to compartmentalize cellular activities and to establish cell polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000636", "l": "positive regulation of primary miRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of primary microRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903833", "l": "positive regulation of cellular response to amino acid starvation", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to amino acid starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905918", "l": "regulation of CoA-transferase activity", "d": ["Any process that modulates the frequency, rate or extent of CoA-transferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0050961", "l": "detection of temperature stimulus involved in sensory perception", "d": ["The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061304", "l": "retinal blood vessel morphogenesis", "d": ["The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110091", "l": "negative regulation of hippocampal neuron apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900822", "l": "regulation of ergot alkaloid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of ergot alkaloid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0048364", "l": "root development", "d": ["The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010188", "l": "response to microbial phytotoxin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a microbial phytotoxin stimulus. A microbial phytotoxin is a chemical substance produced by microbes which is toxic to plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070884", "l": "regulation of calcineurin-NFAT signaling cascade", "d": ["Any process that modulates the frequency, rate or extent of the calcineurin-NFAT signaling cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090120", "l": "lysosome to ER cholesterol transport", "d": ["The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, from the lysosome to the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044149", "l": "positive regulation of formation of structure involved in a symbiotic process", "d": ["Any process that activates or increases the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0010154", "l": "fruit development", "d": ["The process whose specific outcome is the progression of the fruit over time, from its formation to the mature structure. The fruit is a reproductive body of a seed plant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.207992593949683", "identifiers": [{"i": "GO:0016445", "l": "somatic diversification of immunoglobulins", "d": ["The somatic process that results in the generation of sequence diversity of immunoglobulins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0097152", "l": "mesenchymal cell apoptotic process", "d": ["Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900206", "l": "regulation of pronephric nephron tubule development", "d": ["Any process that modulates the frequency, rate or extent of pronephric nephron tubule development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0001658", "l": "branching involved in ureteric bud morphogenesis", "d": ["The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904811", "l": "positive regulation of dense core granule transport", "d": ["Any process that activates or increases the frequency, rate or extent of dense core granule transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0048071", "l": "sex-specific pigmentation", "d": ["Establishment of a pattern of pigment in one sex that is not observed in the other sex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009436", "l": "glyoxylate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glyoxylate, the anion of glyoxylic acid, HOC-COOH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090453", "l": "aspartate transmembrane import into vacuole", "d": ["The directed movement of aspartate into the vacuole across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046690", "l": "response to tellurium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006488", "l": "dolichol-linked oligosaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dolichol-linked oligosaccharide, usually by a stepwise addition of glycosyl chains to endoplasmic reticulum membrane-bound dolichol-P."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036343", "l": "psychomotor behavior", "d": ["The specific behavior of an organism that combines cognitive functions and physical movement. For example, driving a car, throwing a ball, or playing a musical instrument."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0006639", "l": "acylglycerol metabolic process", "d": ["The chemical reactions and pathways involving acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:2000924", "l": "regulation of cellodextrin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellodextrin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900480", "l": "regulation of diacylglycerol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of diacylglycerol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.783030043623796", "identifiers": [{"i": "GO:1902115", "l": "regulation of organelle assembly", "d": ["Any process that modulates the frequency, rate or extent of organelle assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903558", "l": "3-cyano-L-alanine metabolic process", "d": ["The chemical reactions and pathways involving 3-cyano-L-alanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0010053", "l": "root epidermal cell differentiation", "d": ["The process in which a relatively unspecialized cell in the root epidermis acquires the specialized features of a trichoblast or atrichoblast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.26589554577329", "identifiers": [{"i": "GO:0009314", "l": "response to radiation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.062476272212777", "identifiers": [{"i": "GO:0031400", "l": "negative regulation of protein modification process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0045187", "l": "regulation of circadian sleep/wake cycle, sleep", "d": ["Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "16.116700956589671", "identifiers": [{"i": "GO:0009987", "l": "cellular process", "d": ["Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090297", "l": "positive regulation of mitochondrial DNA replication", "d": ["Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021856", "l": "hypothalamic tangential migration using cell-axon interactions", "d": ["The movement of a hypothalamic neuronal precursor tangentially through the forebrain using an interaction of the migrating cells with axons of other neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045574", "l": "sterigmatocystin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0009156", "l": "ribonucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000989", "l": "negative regulation of hemicellulose catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hemicellulose catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009627", "l": "systemic acquired resistance", "d": ["The salicylic acid mediated response to a pathogen which confers broad spectrum resistance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071680", "l": "response to indole-3-methanol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090648", "l": "response to environmental enrichment", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the provision of a combination of complex inanimate and social stimulations in the organism's housing environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048340", "l": "paraxial mesoderm morphogenesis", "d": ["The process in which the anatomical structures of the paraxial mesoderm are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0060026", "l": "convergent extension", "d": ["The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903894", "l": "regulation of IRE1-mediated unfolded protein response", "d": ["Any process that modulates the frequency, rate or extent of the IRE1-mediated unfolded protein response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030393", "l": "fructoselysine metabolic process", "d": ["The chemical reactions and pathways involving fructoselysine, a fructose molecule containing a lysine group in place of a hydroxyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990540", "l": "mitochondrial manganese ion transmembrane transport", "d": ["The process in which a manganese ion is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036358", "l": "lipoteichoic acid D-alanylation", "d": ["The formation of a D-alanyl ester of lipoteichoic acid by transfer of D-Ala onto a membrane-associated lipoteichoic acid (LTA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043319", "l": "positive regulation of cytotoxic T cell degranulation", "d": ["Any process that activates or increases the frequency, rate or extent of cytotoxic T cell degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:0072207", "l": "metanephric epithelium development", "d": ["The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072712", "l": "response to thiabendazole", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002898", "l": "regulation of central B cell deletion", "d": ["Any process that modulates the frequency, rate, or extent of central B cell deletion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045672", "l": "positive regulation of osteoclast differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of osteoclast differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0044472", "l": "envenomation resulting in modulation of calcium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a calcium channel in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045748", "l": "positive regulation of R8 cell spacing in compound eye", "d": ["Any process that activates or enforces the correct R8 cell spacing in a compound eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090140", "l": "regulation of mitochondrial fission", "d": ["Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905686", "l": "positive regulation of plasma membrane repair", "d": ["Any process that activates or increases the frequency, rate or extent of plasma membrane repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060751", "l": "branch elongation involved in mammary gland duct branching", "d": ["The developmental growth process in which a branch of a mammary gland duct elongates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070484", "l": "dehydro-D-arabinono-1,4-lactone metabolic process", "d": ["The chemical reactions and pathways involving dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:1904748", "l": "regulation of apoptotic process involved in development", "d": ["Any process that modulates the frequency, rate or extent of apoptotic process involved in development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052098", "l": "formation by host of specialized structure for nutrient acquisition from symbiont", "d": ["The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0030193", "l": "regulation of blood coagulation", "d": ["Any process that modulates the frequency, rate or extent of blood coagulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.780700721499244", "identifiers": [{"i": "GO:0035150", "l": "regulation of tube size", "d": ["Ensuring that a tube is of the correct length and diameter. Tube size must be maintained not only during tube formation, but also throughout development and in some physiological processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038105", "l": "sequestering of TGFbeta from receptor via TGFbeta binding", "d": ["Binding to a transforming growth factor-beta (TGFbeta) protein in the extracellular region, and inhibiting TGFbeta signaling by preventing TGFbeta from binding to its cell surface receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:1902576", "l": "negative regulation of nuclear cell cycle DNA replication", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nuclear cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902552", "l": "negative regulation of catalase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of catalase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0009218", "l": "pyrimidine ribonucleotide metabolic process", "d": ["The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901164", "l": "negative regulation of trophoblast cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003147", "l": "neural crest cell migration involved in heart formation", "d": ["The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905352", "l": "ciliary necklace assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a ciliary necklace."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018989", "l": "apolysis", "d": ["The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901285", "l": "5,6,7,8-tetrahydromethanopterin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydromethanopterin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010749", "l": "regulation of nitric oxide mediated signal transduction", "d": ["Any process that modulates the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904726", "l": "regulation of replicative senescence", "d": ["Any process that modulates the frequency, rate or extent of replicative senescence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018204", "l": "peptidyl-leucine modification", "d": ["The modification of peptidyl-leucine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061357", "l": "positive regulation of Wnt protein secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905708", "l": "regulation of cell morphogenesis involved in conjugation with cellular fusion", "d": ["Any process that modulates the location, frequency, rate or extent of cell morphogenesis involved in conjugation with cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033604", "l": "negative regulation of catecholamine secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033629", "l": "negative regulation of cell adhesion mediated by integrin", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of cell adhesion mediated by integrin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070317", "l": "negative regulation of G0 to G1 transition", "d": ["A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0022028", "l": "tangential migration from the subventricular zone to the olfactory bulb", "d": ["The migration of cells in the telencephalon from the subventricular zone to the olfactory bulb in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905875", "l": "negative regulation of postsynaptic density organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic density organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0046174", "l": "polyol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905940", "l": "negative regulation of gonad development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gonad development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071234", "l": "cellular response to phenylalanine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031915", "l": "positive regulation of synaptic plasticity", "d": ["A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036274", "l": "response to lapatinib", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0106007", "l": "microtubule anchoring at cell cortex of cell tip", "d": ["Any process in which a microtubule is maintained in a specific location at the cell tip by attachment to the cell cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.362525179576039", "identifiers": [{"i": "GO:0031507", "l": "heterochromatin formation", "d": ["An epigenetic gene silencing mechanism in which chromatin is compacted into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042001", "l": "hermaphrodite somatic sex determination", "d": ["The determination of sex and sexual phenotypes in a hermaphroditic organism's soma. An example of this is found in Caenorhabditis elegans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "50.694337943625953", "identifiers": [{"i": "GO:0043436", "l": "oxoacid metabolic process", "d": ["The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901729", "l": "monensin A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of monensin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061976", "l": "temporomandibular joint articular cartilage development", "d": ["The process whose specific outcome is the progression of temporomandibular joint articular cartilage over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003199", "l": "endocardial cushion to mesenchymal transition involved in heart valve formation", "d": ["A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of a cardiac valve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140067", "l": "peptidyl-lysine butyrylation", "d": ["The butyrylation of a lysine residue in a protein. Butyryl is the univalent radical C3H7COO- derived from butyric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.604754761056498", "identifiers": [{"i": "GO:0010608", "l": "post-transcriptional regulation of gene expression", "d": ["Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0019685", "l": "photosynthesis, dark reaction", "d": ["A complex cycle of enzyme-mediated reactions which catalyzes the reduction of carbon dioxide to sugar. As well as carbon dioxide the cycle requires reducing power in the form of reduced nicotinamide adenine dinucleotide phosphate (NADP) and chemical energy in the form of adenosine triphosphate (ATP). The reduced NADP (NADPH) and ATP are produced by the 'light' reactions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:1904498", "l": "protein localization to mitotic actomyosin contractile ring", "d": ["Any protein localization to actomyosin contractile ring that is involved in mitotic cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901898", "l": "negative regulation of relaxation of cardiac muscle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of cardiac muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048561", "l": "establishment of animal organ orientation", "d": ["The process that determines the orientation of an animal organ or tissue with reference to an axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1900193", "l": "regulation of oocyte maturation", "d": ["Any process that modulates the frequency, rate or extent of oocyte maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900574", "l": "emodin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of emodin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007277", "l": "pole cell development", "d": ["The process whose specific outcome is the progression of the pole cell over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090173", "l": "regulation of synaptonemal complex assembly", "d": ["Any process that modulates the frequency, rate or extent of synaptonemal complex assembly. Synaptonemal complex assembly is the cell cycle process in which the synaptonemal complex, a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination, is formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002296", "l": "T-helper 1 cell lineage commitment", "d": ["The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090093", "l": "regulation of fungal-type cell wall beta-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of fungal-type cell wall beta-glucan biosynthesis, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0055116", "l": "entry into reproductive diapause", "d": ["The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090204", "l": "protein localization to nuclear pore", "d": ["A process in which a protein is transported to, or maintained in, a nuclear pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900124", "l": "negative regulation of nodal receptor complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nodal receptor complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:0030851", "l": "granulocyte differentiation", "d": ["The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060380", "l": "regulation of single-stranded telomeric DNA binding", "d": ["Any process that modulates the frequency, rate or extent of binding to single-stranded telomeric DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071981", "l": "exit from diapause", "d": ["The dormancy process that results in exit from diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.437453848678771", "identifiers": [{"i": "GO:0031424", "l": "keratinization", "d": ["The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0008333", "l": "endosome to lysosome transport", "d": ["The directed movement of substances from endosomes to lysosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000971", "l": "tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate", "d": ["A tRNA exon ligation process in which the splice junction phosphate is derived from the 2',3' cyclic phosphate at the 3'-end of the 5'-exon. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in wheat, Chlamydomonas, and vertebrate species including humans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0048635", "l": "negative regulation of muscle organ development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0052562", "l": "suppression by symbiont of host immune response", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2000589", "l": "regulation of metanephric mesenchymal cell migration", "d": ["Any process that modulates the frequency, rate or extent of metanephric mesenchymal cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900284", "l": "positive regulation of cellobiose catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellobiose catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902822", "l": "regulation of late endosome to lysosome transport", "d": ["Any process that modulates the frequency, rate or extent of late endosome to lysosome transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042894", "l": "fosmidomycin transport", "d": ["The directed movement of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070149", "l": "mitochondrial glutamyl-tRNA aminoacylation", "d": ["The process of coupling glutamate to glutamyl-tRNA in a mitochondrion, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006421", "l": "asparaginyl-tRNA aminoacylation", "d": ["The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an asparagine-accetping tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098932", "l": "disruption by virus of host cell wall peptidoglycan during virus entry", "d": ["A process carried out by a virus that breaks down peptidoglycans in the cell wall of its host during viral entry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002488", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class Ib molecule in the ER. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902888", "l": "protein localization to astral microtubule", "d": ["A process in which a protein is transported to, or maintained in, a location within an astral microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001782", "l": "B cell homeostasis", "d": ["The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014737", "l": "positive regulation of muscle atrophy", "d": ["Any process that activates or increases the frequency, rate or extent of muscle atrophy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900934", "l": "positive regulation of nonadec-1-ene metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of nonadec-1-ene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:2000895", "l": "hemicellulose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a hemicellulose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.378002841413903", "identifiers": [{"i": "GO:0042325", "l": "regulation of phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0032413", "l": "negative regulation of ion transmembrane transporter activity", "d": ["Any process that stops or reduces the activity of an ion transporter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046787", "l": "viral DNA repair", "d": ["The process of restoring viral DNA after damage or errors in replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051104", "l": "DNA-dependent DNA replication DNA ligation", "d": ["The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA-dependent DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061367", "l": "behavioral response to acetic acid induced pain", "d": ["Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046308", "l": "Z-phenylacetaldoxime catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:1902337", "l": "regulation of apoptotic process involved in morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0000050", "l": "urea cycle", "d": ["The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031337", "l": "positive regulation of sulfur amino acid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002656", "l": "negative regulation of tolerance induction to nonself antigen", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to nonself antigen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060649", "l": "mammary gland bud elongation", "d": ["The process in which the mammary gland bud grows along its axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010938", "l": "cytoplasmic microtubule depolymerization", "d": ["The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0046633", "l": "alpha-beta T cell proliferation", "d": ["The expansion of an alpha-beta T cell population by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010836", "l": "negative regulation of protein ADP-ribosylation", "d": ["Any process that decreases the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002874", "l": "regulation of chronic inflammatory response to antigenic stimulus", "d": ["Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039006", "l": "pronephric nephron tubule formation", "d": ["The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000713", "l": "meiotic heteroduplex formation", "d": ["During meiosis, the formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000230", "l": "negative regulation of pancreatic stellate cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic stellate cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.585103934178449", "identifiers": [{"i": "GO:0060096", "l": "serotonin secretion, neurotransmission", "d": ["The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050691", "l": "regulation of defense response to virus by host", "d": ["Any host process that modulates the frequency, rate, or extent of the antiviral response of a host cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0043502", "l": "regulation of muscle adaptation", "d": ["Any process that modulates the frequency, rate or extent of muscle adaptation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.444551060876734", "identifiers": [{"i": "GO:0019048", "l": "modulation by virus of host process", "d": ["The process in which a virus effects a change in the structure or processes of its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034517", "l": "ribophagy", "d": ["The selective autophagy process in which cells degrade mature ribosomes under conditions of starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035151", "l": "regulation of tube size, open tracheal system", "d": ["Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060656", "l": "regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling", "d": ["Any process that modulates the rate, frequency, or extent of branching of the mammary gland cord as a result of a signal being created by a mammary fat precursor cell and its subsequent reception and interpretation by a mammary cord epithelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021670", "l": "lateral ventricle development", "d": ["The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.569439710577498", "identifiers": [{"i": "GO:0007131", "l": "reciprocal meiotic recombination", "d": ["The cell cycle process in which double strand breaks are formed and repaired through a single or double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0039637", "l": "catabolism by virus of host DNA", "d": ["The breakdown of host DNA, deoxyribonucleic acid, by a virus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061510", "l": "asymmetric protein localization to new mitotic spindle pole body", "d": ["Any process in which a protein is transported to, or maintained to the new mitotic spindle pole body resulting in its being distributed asymmetrically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009127", "l": "purine nucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904541", "l": "fungal-type cell wall disassembly involved in conjugation with cellular fusion", "d": ["Any fungal-type cell wall disassembly that is involved in conjugation with cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0098708", "l": "glucose import across plasma membrane", "d": ["The directed movement of glucose from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905960", "l": "response to differentiation-inducing factor 2", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022020", "l": "medial ganglionic eminence cell proliferation", "d": ["The multiplication or reproduction of medial ganglionic eminence cells, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021567", "l": "rhombomere 1 development", "d": ["The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002844", "l": "negative regulation of tolerance induction to tumor cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000520", "l": "regulation of immunological synapse formation", "d": ["Any process that modulates the frequency, rate or extent of immunological synapse formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140533", "l": "suppression of host RNAi-mediated antiviral immune response", "d": ["Any process in which a symbiont stops, prevents, or reduces the rate or extent of the host's RNAi-mediated antiviral immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035746", "l": "granzyme A production", "d": ["The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905640", "l": "response to acetaldehyde", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060767", "l": "epithelial cell proliferation involved in prostate gland development", "d": ["The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034260", "l": "negative regulation of GTPase activity", "d": ["Any process that stops or reduces the rate of GTP hydrolysis by a GTPase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904196", "l": "negative regulation of granulosa cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905655", "l": "negative regulation of artery smooth muscle contraction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of artery smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046043", "l": "TDP metabolic process", "d": ["The chemical reactions and pathways involving TDP, ribosylthymine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902472", "l": "regulation of mitotic cytokinesis, division site positioning", "d": ["Any process that modulates the frequency, rate or extent of mitotic cytokinesis, division site positioning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0006383", "l": "transcription by RNA polymerase III", "d": ["The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0035019", "l": "somatic stem cell population maintenance", "d": ["Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002869", "l": "positive regulation of B cell deletion", "d": ["Any process that activates or increases the frequency, rate, or extent of B cell deletion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0000052", "l": "citrulline metabolic process", "d": ["The chemical reactions and pathways involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000870", "l": "regulation of progesterone secretion", "d": ["Any process that modulates the frequency, rate or extent of progesterone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901694", "l": "positive regulation of compound eye retinal cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.35073291073661", "identifiers": [{"i": "GO:0051247", "l": "positive regulation of protein metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0106118", "l": "regulation of sterol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of a sterol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903920", "l": "positive regulation of actin filament severing", "d": ["Any process that activates or increases the frequency, rate or extent of actin filament severing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046340", "l": "diacylglycerol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000882", "l": "negative regulation of starch catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of starch catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000396", "l": "negative regulation of ubiquitin-dependent endocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin-dependent endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021635", "l": "trigeminal nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0032374", "l": "regulation of cholesterol transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007561", "l": "imaginal disc eversion", "d": ["The eversion (turning inside out) of imaginal discs from their peripodial sacs, resulting in movement of the epithelium to the outside of the larval epidermis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0001580", "l": "detection of chemical stimulus involved in sensory perception of bitter taste", "d": ["The series of events required for a bitter taste stimulus to be received and converted to a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001295", "l": "malonyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000536", "l": "negative regulation of entry of bacterium into host cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of entry of bacterium into host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901850", "l": "7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolic process", "d": ["The chemical reactions and pathways involving 7,8-didemethyl-8-hydroxy-5-deazariboflavin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900111", "l": "positive regulation of histone H3-K9 dimethylation", "d": ["Any process that activates or increases the frequency, rate or extent of histone H3-K9 dimethylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072027", "l": "connecting tubule development", "d": ["The process whose specific outcome is the progression of the connecting tubule over time, from its formation to the mature structure. The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900237", "l": "positive regulation of induction of conjugation with cellular fusion", "d": ["Any process that activates or increases the frequency, rate or extent of induction of conjugation with cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014707", "l": "branchiomeric skeletal muscle development", "d": ["The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0010191", "l": "mucilage metabolic process", "d": ["The chemical reactions and pathways involving mucilage, a gelatinous substance secreted by plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021634", "l": "optic nerve formation", "d": ["The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035707", "l": "T-helper 2 cell chemotaxis", "d": ["The directed movement of a T-helper 2 cell in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0097087", "l": "interleukin-17A production", "d": ["The appearance of interleukin-17A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061282", "l": "specification of mesonephric nephron tubule identity", "d": ["The process in which the tubules arranged along the proximal/distal axis of the mesonephric nephron acquire their identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901624", "l": "negative regulation of lymphocyte chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071770", "l": "DIM/DIP cell wall layer assembly", "d": ["The aggregation, arrangement and bonding together of a set of components, including (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate and diphthioceranate, to form the DIM/DIP layer of the Actinobacterium-type cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002946", "l": "tRNA C5-cytosine methylation", "d": ["The process whereby a cytosine in a tRNA is methylated at position 5 of the cytosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060844", "l": "arterial endothelial cell fate commitment", "d": ["The commitment of a cell to an arterial endothelial cell fate and its capacity to differentiate into an arterial endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060587", "l": "regulation of lipoprotein lipid oxidation", "d": ["Any process that modulates the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0038009", "l": "regulation of signal transduction by receptor internalization", "d": ["Any process that modulates the frequency, rate or extent of signal transduction by the movement of a signaling receptor from the plasma membrane to the inside of the cell. Receptor internalization can have a positive or negative effect on a signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:0001754", "l": "eye photoreceptor cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904617", "l": "negative regulation of actin binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of actin binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0006878", "l": "intracellular copper ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of copper ions within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900894", "l": "negative regulation of tridecane metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tridecane metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007290", "l": "spermatid nucleus elongation", "d": ["The change in shape of the spermatid nucleus from a spherical structure to an elongated organelle, during the latter part of spermatid differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.651613913496419", "identifiers": [{"i": "GO:0016101", "l": "diterpenoid metabolic process", "d": ["The chemical reactions and pathways involving diterpenoid compounds, terpenoids with four isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090359", "l": "negative regulation of abscisic acid biosynthetic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046069", "l": "cGMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cyclic GMP, guanosine 3',5'-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903368", "l": "regulation of foraging behavior", "d": ["Any process that modulates the frequency, rate or extent of foraging behavior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120332", "l": "host-mediated regulation of oral microbiota composition", "d": ["The biological process involved in maintaining the steady-state number of cells within a population of free-living cells, such as the bacteria, in the mouth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901284", "l": "5,6,7,8-tetrahydromethanopterin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydromethanopterin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:2001135", "l": "regulation of endocytic recycling", "d": ["Any process that modulates the frequency, rate or extent of endocytic recycling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0140405", "l": "spindle pole body-led chromosome movement during mitotic interphase", "d": ["A microtubule-based process in which chromosomes migrate as a result of rapid spindle pole body (SPB) and centrosome oscillations during mitotic interphase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035224", "l": "genital disc anterior/posterior pattern formation", "d": ["The establishment, maintenance and elaboration of the anterior/posterior axis of the genital disc. An anterior and posterior compartment form in each of the three genital disc primoridia (the female genital disc primordium, the male genital disc primordium and the anal primordium)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003172", "l": "sinoatrial valve development", "d": ["The progression of the sinoatrial valve over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046047", "l": "TTP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of TTP, ribosylthymine triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0048882", "l": "lateral line development", "d": ["The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0010325", "l": "raffinose family oligosaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of raffinose family oligosaccharides (RFOs, such as raffinose, stachyose, verbascose and other molecules with a higher degree of galactosyl polymerization)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0042447", "l": "hormone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009238", "l": "enterobactin metabolic process", "d": ["The chemical reactions and pathways involving enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0045576", "l": "mast cell activation", "d": ["The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0039667", "l": "viral entry into host cell via pilus retraction", "d": ["The uptake of a virus or viral genetic material into a host cell which occurs through retraction of a virion-bound pilus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055016", "l": "hypochord development", "d": ["The process whose specific outcome is the progression of the hypochord over time, from its formation to the mature structure. The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010520", "l": "regulation of reciprocal meiotic recombination", "d": ["Any process that modulates the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0019348", "l": "dolichol metabolic process", "d": ["The chemical reactions and pathways involving dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018867", "l": "alpha-pinene metabolic process", "d": ["The chemical reactions and pathways involving alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. It is a major component in tea-tree oils, and gives off a piney smelling odor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060141", "l": "positive regulation of syncytium formation by virus", "d": ["The process in which a virus increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000068", "l": "regulation of defense response to insect", "d": ["Any process that modulates the frequency, rate or extent of defense response to insect."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120221", "l": "maintenance of ciliary planar beating movement pattern", "d": ["Any process involved in maintaining the planar beating pattern of ciliary movement pattern. Connection between the outer doublets and the central pair via the radial spokes constrains ciliary movement to the planar beating pattern. Cilia that lack this connection, such as those in the embryonic node or Kupfer's vesicle, display radial movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:0048438", "l": "floral whorl development", "d": ["The process whose specific outcome is the progression of a floral whorl over time, from its formation to the mature structure. A floral whorl is a circular arrangement of parts of a flower arising from a stem of a plant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048209", "l": "regulation of vesicle targeting, to, from or within Golgi", "d": ["Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090333", "l": "regulation of stomatal closure", "d": ["Any process that modulates the rate, frequency, or extent of stomatal closure. Stomatal closure is the process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032049", "l": "cardiolipin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060327", "l": "cytoplasmic actin-based contraction involved in cell motility", "d": ["The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell from one place to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:1902513", "l": "regulation of organelle transport along microtubule", "d": ["Any process that modulates the frequency, rate or extent of organelle transport along microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060620", "l": "regulation of cholesterol import", "d": ["Any process that modulates the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902320", "l": "nuclear DNA replication DNA duplex unwinding", "d": ["Any DNA duplex unwinding that is involved in nuclear cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032818", "l": "negative regulation of natural killer cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010037", "l": "response to carbon dioxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902648", "l": "positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002513", "l": "tolerance induction to self antigen", "d": ["Tolerance induction directed at self antigens."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0008334", "l": "histone mRNA metabolic process", "d": ["The chemical reactions and pathways involving an mRNA encoding a histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:2001244", "l": "positive regulation of intrinsic apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044722", "l": "renal phosphate excretion", "d": ["The elimination of phosphate ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062142", "l": "L-beta-ethynylserine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-beta-ethynylserine. L-beta-ethynylserine is an antibiotic produced by Streptomyces bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045492", "l": "xylan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of xylan, a polymer containing a beta-1,4-linked D-xylose backbone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000521", "l": "negative regulation of immunological synapse formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of immunological synapse formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0015908", "l": "fatty acid transport", "d": ["The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901289", "l": "succinyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of succinyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902745", "l": "positive regulation of lamellipodium organization", "d": ["Any process that activates or increases the frequency, rate or extent of lamellipodium organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010879", "l": "cholesterol transport involved in cholesterol storage", "d": ["The directed movement of cholesterol into cells that is part of their accumulation and maintenance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070982", "l": "L-asparagine metabolic process", "d": ["The chemical reactions and pathways involving L-asparagine, (2S)-2-amino-3-carbamoylpropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035475", "l": "angioblast cell migration involved in selective angioblast sprouting", "d": ["The directional migration of angioblast cells as part of selective angioblast sprouting, which results in angioblast segregation into arterial and venous populations."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001014", "l": "snoRNA transcription by RNA polymerase III", "d": ["The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase III, originating at a type 2 RNA polymerase III promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0007469", "l": "antennal development", "d": ["The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0001504", "l": "neurotransmitter uptake", "d": ["The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0021535", "l": "cell migration in hindbrain", "d": ["The orderly movement of a cell that will reside in the hindbrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007035", "l": "vacuolar acidification", "d": ["Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098880", "l": "maintenance of postsynaptic specialization structure", "d": ["A process which maintains the organization and the arrangement of proteins in the presynaptic specialization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0001952", "l": "regulation of cell-matrix adhesion", "d": ["Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0071709", "l": "membrane assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006428", "l": "isoleucyl-tRNA aminoacylation", "d": ["The process of coupling isoleucine to isoleucyl-tRNA, catalyzed by isoleucyl-tRNA synthetase. The isoleucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a isoleucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048928", "l": "posterior lateral line ganglion neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048459", "l": "floral whorl structural organization", "d": ["The process that contributes to the act of creating the structural organization of the floral whorl. This process pertains to the physical shaping of a rudimentary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097019", "l": "neurotransmitter receptor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of neurotransmitter receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0042068", "l": "regulation of pteridine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pteridine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010956", "l": "negative regulation of calcidiol 1-monooxygenase activity", "d": ["Any process that decreases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0046461", "l": "neutral lipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of neutral lipids, lipids only soluble in solvents of very low polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006015", "l": "5-phosphoribose 1-diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1905779", "l": "positive regulation of exonuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of exonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0140115", "l": "export across plasma membrane", "d": ["The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061225", "l": "mesonephric extraglomerular mesangial cell proliferation involved in mesonephros development", "d": ["The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016038", "l": "absorption of visible light", "d": ["The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902643", "l": "positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034252", "l": "negative regulation of amide catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "37.036401214372951", "identifiers": [{"i": "GO:0051234", "l": "establishment of localization", "d": ["Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0048286", "l": "lung alveolus development", "d": ["The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901735", "l": "(R)-mevalonic acid metabolic process", "d": ["The chemical reactions and pathways involving (R)-mevalonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0034182", "l": "regulation of maintenance of mitotic sister chromatid cohesion", "d": ["Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007497", "l": "posterior midgut development", "d": ["The process whose specific outcome is the progression of the posterior midgut over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048888", "l": "neuromast mantle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0050864", "l": "regulation of B cell activation", "d": ["Any process that modulates the frequency, rate or extent of B cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0002836", "l": "positive regulation of response to tumor cell", "d": ["Any process that activates or increases the frequency, rate, or extent of a response to tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009128", "l": "purine nucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071317", "l": "cellular response to isoquinoline alkaloid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0045991", "l": "carbon catabolite activation of transcription", "d": ["A transcription regulation process in which the presence of one carbon source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0006701", "l": "progesterone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0003207", "l": "cardiac chamber formation", "d": ["The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003175", "l": "tricuspid valve development", "d": ["The progression of the tricuspid valve over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034143", "l": "regulation of toll-like receptor 4 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070672", "l": "response to interleukin-15", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061561", "l": "trigeminal ganglion formation", "d": ["The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990546", "l": "mitochondrial tricarboxylic acid transmembrane transport", "d": ["The process in which a tricarboxylic acid is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034491", "l": "neutral amino acid transmembrane import into vacuole", "d": ["The directed movement of neutral amino acids into the vacuole across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051484", "l": "isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway that contributes to terpenoid biosynthesis. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0021513", "l": "spinal cord dorsal/ventral patterning", "d": ["The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032597", "l": "B cell receptor transport into membrane raft", "d": ["The directed movement of a B cell receptor into a membrane raft."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901953", "l": "positive regulation of anterograde dense core granule transport", "d": ["Any process that activates or increases the frequency, rate or extent of anterograde dense core granule transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1905245", "l": "regulation of aspartic-type peptidase activity", "d": ["Any process that modulates the frequency, rate or extent of aspartic-type peptidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060657", "l": "regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling", "d": ["Any process that modulates the rate, frequency, or extent of mammary gland cord elongation as a result of a signal being created by a mesenchymal cell that is a precursor to the mammary fat and its subsequent reception and interpretation by an mammary cord epithelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002678", "l": "positive regulation of chronic inflammatory response", "d": ["Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905382", "l": "positive regulation of snRNA transcription by RNA polymerase II", "d": ["Any process that activates or increases the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.568031979160473", "identifiers": [{"i": "GO:0023057", "l": "negative regulation of signaling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032285", "l": "non-myelinated axon ensheathment", "d": ["The process in which a non-myelinating glial cell membrane closes around an axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0070527", "l": "platelet aggregation", "d": ["The adhesion of one platelet to one or more other platelets via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.706877558974412", "identifiers": [{"i": "GO:0060485", "l": "mesenchyme development", "d": ["The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901851", "l": "7,8-didemethyl-8-hydroxy-5-deazariboflavin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 7,8-didemethyl-8-hydroxy-5-deazariboflavin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.303328383464915", "identifiers": [{"i": "GO:0006939", "l": "smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000345", "l": "regulation of hepatocyte proliferation", "d": ["Any process that modulates the frequency, rate or extent of hepatocyte proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905605", "l": "positive regulation of blood-brain barrier permeability", "d": ["Any process that increases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902134", "l": "(+)-secoisolariciresinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (+)-secoisolariciresinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140216", "l": "negative regulation of D-aspartate import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905850", "l": "positive regulation of forward locomotion", "d": ["Any process that activates or increases the frequency, rate or extent of forward locomotion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006689", "l": "ganglioside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070458", "l": "cellular detoxification of nitrogen compound", "d": ["Any cellular process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0060964", "l": "regulation of miRNA-mediated gene silencing", "d": ["A process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032658", "l": "regulation of interleukin-15 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-15 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1900108", "l": "negative regulation of nodal signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nodal signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000529", "l": "positive regulation of myeloid dendritic cell chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904102", "l": "cellular response to acadesine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061722", "l": "sulphoglycolysis", "d": ["The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and pyruvate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070135", "l": "beta-1,2-oligomannoside metabolic process", "d": ["The chemical reactions and pathways involving beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033861", "l": "negative regulation of NAD(P)H oxidase activity", "d": ["Any process that stops or reduces the activity of the enzyme NAD(P)H oxidase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905687", "l": "regulation of diacylglycerol kinase activity", "d": ["Any process that modulates the frequency, rate or extent of diacylglycerol kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097012", "l": "response to granulocyte macrophage colony-stimulating factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.384166970983159", "identifiers": [{"i": "GO:0071704", "l": "organic substance metabolic process", "d": ["The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034156", "l": "negative regulation of toll-like receptor 7 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 7 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904934", "l": "negative regulation of cell proliferation in midbrain", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002415", "l": "immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor", "d": ["The process of transporting polymeric IgA and polymeric IgM immunoglobulin, via transcytosis mediated by the polymeric immunoglobulin receptor (pIgR), from the basolateral surface to apical surface of an epithelial cell. At the apical surface the immunoglobulin binding portion of the pIgRis cleaved and remains bound to the transported immunoglobulin as secretory component (SC). The same process is used for the transport and excretion of IgA immune complexes to the luminal surface of the mucosa."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035146", "l": "tube fusion", "d": ["The joining of specific branches of a tubular system to form a continuous network."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0043666", "l": "regulation of phosphoprotein phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of phosphoprotein phosphatase activity, the catalysis of the hydrolysis of phosphate from a phosphoprotein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0042748", "l": "circadian sleep/wake cycle, non-REM sleep", "d": ["All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900887", "l": "regulation of pentadecane biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of pentadecane biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903847", "l": "regulation of aorta morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of aorta morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000980", "l": "regulation of inner ear receptor cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of inner ear receptor cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075218", "l": "zoospore encystment on host", "d": ["The physiological, developmental and morphological changes that occur in a symbiont zoospore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060391", "l": "positive regulation of SMAD protein signal transduction", "d": ["Any process that increases the rate, frequency or extent of SMAD protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900968", "l": "regulation of sarcinapterin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of sarcinapterin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044733", "l": "envenomation resulting in modulation of acid-sensing ion channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an acid-sensing ion channel (ASIC) in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071583", "l": "negative regulation of zinc ion transmembrane transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0009838", "l": "abscission", "d": ["The controlled shedding of a body part."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036510", "l": "trimming of terminal mannose on C branch", "d": ["The removal of an alpha-1,2-linked mannose from the C-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900756", "l": "protein processing in phagocytic vesicle", "d": ["Protein processing that takes place in the phagosome. Most protein processing in the phagosome represents protein degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033156", "l": "oligogalacturonide transport", "d": ["The directed movement of oligogalacturonides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0043077", "l": "initiation of acetate catabolic process", "d": ["The activation of the chemical reactions and pathways resulting in the breakdown of acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098005", "l": "viral head-tail joining", "d": ["Process by which virus heads and tails are attached to each other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0120063", "l": "stomach smooth muscle contraction", "d": ["A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs throughout the length of the stomach."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0070988", "l": "demethylation", "d": ["The process of removing one or more methyl groups from a molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036520", "l": "astrocyte-dopaminergic neuron signaling", "d": ["Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0098659", "l": "inorganic cation import across plasma membrane", "d": ["The directed movement of inorganic cations from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032257", "l": "maintenance of dense core granule location", "d": ["Any process in which a dense core granule is maintained in a specific location within a cell and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060540", "l": "diaphragm morphogenesis", "d": ["The process in which the anatomical structures of the diaphragm are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0043697", "l": "cell dedifferentiation", "d": ["The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009645", "l": "response to low light intensity stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900691", "l": "positive regulation of gliotoxin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of gliotoxin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901686", "l": "glutathione derivative catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glutathione derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001807", "l": "regulation of type IV hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of type IV hypersensitivity, a type of inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901660", "l": "calcium ion export", "d": ["The directed movement of calcium ion out of a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044476", "l": "envenomation resulting in negative regulation of low voltage-gated calcium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a low voltage-gated calcium channel in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0032637", "l": "interleukin-8 production", "d": ["The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046401", "l": "lipopolysaccharide core region metabolic process", "d": ["The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues. The structure of this core oligosaccharide appears to be similar in closely related bacterial strains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900815", "l": "monodictyphenone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monodictyphenone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "51.096199538420983", "identifiers": [{"i": "GO:0006936", "l": "muscle contraction", "d": ["A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0015864", "l": "pyrimidine nucleoside transport", "d": ["The directed movement of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.505763639973935", "identifiers": [{"i": "GO:0046907", "l": "intracellular transport", "d": ["The directed movement of substances within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:1903524", "l": "positive regulation of blood circulation", "d": ["Any process that activates or increases the frequency, rate or extent of blood circulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021812", "l": "neuronal-glial interaction involved in cerebral cortex radial glia guided migration", "d": ["The changes in adhesion between neuronal cells and glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075183", "l": "infection cushion formation", "d": ["The process in which an organized mass of hyphae is formed and numerous infective hyphae develop from the hyphae mass."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075502", "l": "endosome membrane permeabilization involved in viral entry into host cell", "d": ["Induction of endosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus through the endosomal pathway, and results in delivery of the virus contents into the host cell cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.825956045430587", "identifiers": [{"i": "GO:0099500", "l": "vesicle fusion to plasma membrane", "d": ["Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0072047", "l": "proximal/distal pattern formation involved in nephron development", "d": ["The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0001553", "l": "luteinization", "d": ["The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905747", "l": "negative regulation of saliva secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of saliva secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903213", "l": "protein localization to subtelomeric heterochromatin", "d": ["A process in which a protein is transported to, or maintained in, a location within a subtelomeric heterochromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1900719", "l": "regulation of uterine smooth muscle relaxation", "d": ["Any process that modulates the frequency, rate or extent of uterine smooth muscle relaxation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071218", "l": "cellular response to misfolded protein", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0046718", "l": "viral entry into host cell", "d": ["The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.777964009505382", "identifiers": [{"i": "GO:0006112", "l": "energy reserve metabolic process", "d": ["The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019631", "l": "quinate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of quinate, the anion of quinic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.282684029872676", "identifiers": [{"i": "GO:0007059", "l": "chromosome segregation", "d": ["The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000231", "l": "positive regulation of pancreatic stellate cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of pancreatic stellate cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098943", "l": "neurotransmitter receptor transport, postsynaptic endosome to lysosome", "d": ["The directed movement of neurotransmitter receptor from the postsynaptic endosome in tranpsort vesicles to the lysosome for degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007518", "l": "myoblast fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0097722", "l": "sperm motility", "d": ["Any process involved in the controlled movement of a sperm cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060367", "l": "sagittal suture morphogenesis", "d": ["The process in which the sagittal suture is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1901579", "l": "positive regulation of alkane biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of alkane biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0090494", "l": "dopamine uptake", "d": ["The directed movement of dopamine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010733", "l": "positive regulation of protein glutathionylation", "d": ["Any process that increases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0070129", "l": "regulation of mitochondrial translation", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099123", "l": "somato-dendritic dopamine secretion", "d": ["The regulated release of dopamine from the somatodendritic compartment (cell body or dendrites) of a neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045344", "l": "negative regulation of MHC class I biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051136", "l": "regulation of NK T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of natural killer T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2001225", "l": "regulation of chloride transport", "d": ["Any process that modulates the frequency, rate or extent of chloride transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090016", "l": "regulation of leaflet formation", "d": ["Any process that modulates the frequency, rate or extent of leaflet formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034727", "l": "piecemeal microautophagy of the nucleus", "d": ["Degradation of a cell nucleus by lysosomal microautophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070478", "l": "nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay", "d": ["The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006246", "l": "dTDP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dTDP, deoxyribosylthymine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904061", "l": "positive regulation of locomotor rhythm", "d": ["Any process that activates or increases the frequency, rate or extent of locomotor rhythm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035876", "l": "maintenance of meiotic sister chromatid cohesion, arms", "d": ["The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000760", "l": "adaptation to pheromone regulating conjugation with mutual genetic exchange", "d": ["In organisms that undergo conjugation without cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0045948", "l": "positive regulation of translational initiation", "d": ["Any process that activates or increases the frequency, rate or extent of translational initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903840", "l": "response to arsenite(3-)", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1903909", "l": "regulation of receptor clustering", "d": ["Any process that modulates the frequency, rate or extent of receptor clustering."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000729", "l": "positive regulation of mesenchymal cell proliferation involved in ureter development", "d": ["Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035153", "l": "epithelial cell type specification, open tracheal system", "d": ["Allocation of epithelial cells within each migrating branch in an open tracheal system to distinct tracheal cell fates. During the migration phase each branch forms a well-defined number of cell types (including fusion cells, terminal cells and branch cells) at precise positions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0021806", "l": "initiation of movement involved in cerebral cortex radial glia guided migration", "d": ["The initial stages of cell motility involved in the glial-mediated movement of cells in the developing cerebral cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0051905", "l": "establishment of pigment granule localization", "d": ["The directed movement of a pigment granule to a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021969", "l": "corticospinal neuron axon guidance through the cerebral peduncle", "d": ["The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the internal capsule through the cerebral peduncle in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0110110", "l": "positive regulation of animal organ morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0021781", "l": "glial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001150", "l": "positive regulation of dipeptide transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of dipeptide transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045069", "l": "regulation of viral genome replication", "d": ["Any process that modulates the frequency, rate or extent of viral genome replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0002344", "l": "B cell affinity maturation", "d": ["The process in which B cells produce antibodies with increased antigen affinity. This is accomplished by somatic hypermutation and selection for B cells which produce higher affinity antibodies to antigen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035541", "l": "negative regulation of SNARE complex disassembly", "d": ["Any process that decreases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:1904951", "l": "positive regulation of establishment of protein localization", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of protein localization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905683", "l": "peroxisome disassembly", "d": ["The disaggregation of a peroxisome into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0060374", "l": "mast cell differentiation", "d": ["The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061036", "l": "positive regulation of cartilage development", "d": ["Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900152", "l": "negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034444", "l": "regulation of plasma lipoprotein oxidation", "d": ["Any process that modulates the frequency, rate or extent of lipoprotein oxidation, occurring in the blood plasma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902174", "l": "positive regulation of keratinocyte apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of keratinocyte apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904006", "l": "negative regulation of phospholipase D activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase D activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060161", "l": "positive regulation of dopamine receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the dopamine receptor protein signaling pathway. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044505", "l": "positive regulation of G protein-coupled receptor activity in another organism", "d": ["A process that activates or increases the frequency, rate or extent of the activity of a G protein-coupled receptor in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0003181", "l": "atrioventricular valve morphogenesis", "d": ["The process in which the structure of the atrioventricular valve is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0006641", "l": "triglyceride metabolic process", "d": ["The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008057", "l": "eye pigment granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045887", "l": "positive regulation of synaptic assembly at neuromuscular junction", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic assembly at neuromuscular junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901399", "l": "negative regulation of transforming growth factor beta3 activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta3 activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070673", "l": "response to interleukin-18", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900885", "l": "negative regulation of tridecane biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tridecane biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072316", "l": "alpha-glucan catabolic process involved in ascospore release from ascus", "d": ["The chemical reactions and pathways resulting in the breakdown of alpha-glucans in the ascus wall that contributes to the release of ascospores from the ascus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009997", "l": "negative regulation of cardioblast cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from specifying into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046182", "l": "L-idonate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0009273", "l": "peptidoglycan-based cell wall biogenesis", "d": ["The chemical reactions and pathways resulting in the formation of the peptidoglycan-based cell wall. An example of this process is found in Escherichia coli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903055", "l": "positive regulation of extracellular matrix organization", "d": ["Any process that activates or increases the frequency, rate or extent of extracellular matrix organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901598", "l": "(-)-pinoresinol metabolic process", "d": ["The chemical reactions and pathways involving (-)-pinoresinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901130", "l": "gentamycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of gentamycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060979", "l": "vasculogenesis involved in coronary vascular morphogenesis", "d": ["The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140196", "l": "positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process", "d": ["Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044494", "l": "envenomation resulting in positive regulation of voltage-gated sodium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation or increase in the activity of the activity of a voltage-gated sodium channel in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0061774", "l": "cohesin unloading", "d": ["Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098963", "l": "dendritic transport of messenger ribonucleoprotein complex", "d": ["The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010839", "l": "negative regulation of keratinocyte proliferation", "d": ["Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015013", "l": "heparan sulfate proteoglycan biosynthetic process, linkage to polypeptide", "d": ["The polymerization of one or more heparan sulfate chains via a xylose link onto serine residues in the core protein of a proteoglycan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018952", "l": "parathion metabolic process", "d": ["The chemical reactions and pathways involving parathion, a highly toxic organophosphate compound formerly used as a broad spectrum insecticide, acaricide, fumigant and nematocide. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009217", "l": "purine deoxyribonucleoside triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901750", "l": "leukotriene D4 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of leukotriene D4."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.585103934178449", "identifiers": [{"i": "GO:0031128", "l": "developmental induction", "d": ["A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0007000", "l": "nucleolus organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021731", "l": "trigeminal motor nucleus development", "d": ["The process whose specific outcome is the progression of the trigeminal motor nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035714", "l": "cellular response to nitrogen dioxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061391", "l": "negative regulation of direction of cell growth", "d": ["Any process that decreases the direction of cell growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0071425", "l": "hematopoietic stem cell proliferation", "d": ["The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043612", "l": "isoprene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isoprene, C5H8."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.066601674840506", "identifiers": [{"i": "GO:0051051", "l": "negative regulation of transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.415093686714229", "identifiers": [{"i": "GO:0120178", "l": "steroid hormone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.65725529370583", "identifiers": [{"i": "GO:0006518", "l": "peptide metabolic process", "d": ["The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016204", "l": "determination of muscle attachment site", "d": ["The process that mediates the transfer of information from the cells of a muscle to those of its intended target, thereby identifying the target site."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002364", "l": "NK T cell lineage commitment", "d": ["The process in which a pro-T cell becomes committed to becoming an NK T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046430", "l": "non-phosphorylated glucose metabolic process", "d": ["The chemical reactions and pathways involving non-phosphorylated forms of glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902520", "l": "response to doxorubicin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903905", "l": "positive regulation of establishment of T cell polarity", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071610", "l": "chemokine (C-C motif) ligand 1 production", "d": ["The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901295", "l": "regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment", "d": ["Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039525", "l": "modulation by virus of host chromatin organization", "d": ["Any process in which a virus effects a change in the organization of chromatin in the host."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046197", "l": "orcinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0009826", "l": "unidimensional cell growth", "d": ["The process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.905555711669919", "identifiers": [{"i": "GO:1903829", "l": "positive regulation of protein localization", "d": ["Any process that activates or increases the frequency, rate or extent of a protein localization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010419", "l": "rhamnogalacturonan II side chain metabolic process", "d": ["The chemical reactions and pathways involving the side chains of pectic rhamnogalacturonan II. A number of structurally distinct di- and oligosaccharides can be attached to the C-3 and C-2 of the backbone, respectively."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0007132", "l": "meiotic metaphase I", "d": ["The cell cycle phase, following prophase I, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.188826368221726", "identifiers": [{"i": "GO:0071692", "l": "protein localization to extracellular region", "d": ["Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0055068", "l": "cobalt ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of cobalt ions within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060313", "l": "negative regulation of blood vessel remodeling", "d": ["Any process that decreases the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.465174152298118", "identifiers": [{"i": "GO:0031670", "l": "cellular response to nutrient", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062139", "l": "camera-type eye photoreceptor cell development", "d": ["The process whose specific outcome is the progression of a light-responsive receptor in a camera-type eye over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902006", "l": "negative regulation of proline biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of proline biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035644", "l": "phosphoanandamide dephosphorylation", "d": ["The process of removing one or more phosphate groups from a phosphorylated anandamide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0031397", "l": "negative regulation of protein ubiquitination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002895", "l": "regulation of central B cell tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of central B cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900789", "l": "pseurotin A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pseurotin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901716", "l": "negative regulation of gamma-aminobutyric acid catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.675373588411375", "identifiers": [{"i": "GO:0008300", "l": "isoprenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051036", "l": "regulation of endosome size", "d": ["Any process that modulates the volume of an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031383", "l": "regulation of mating projection assembly", "d": ["Any process that modulates the frequency, rate, or extent of mating projection formation by unicellular fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033595", "l": "response to genistein", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0018199", "l": "peptidyl-glutamine modification", "d": ["The modification of peptidyl-glutamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904313", "l": "response to methamphetamine hydrochloride", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006686", "l": "sphingomyelin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045163", "l": "clustering of voltage-gated potassium channels", "d": ["The process in which voltage-gated potassium channels become localized together in high densities. In animals, voltage-gated potassium (Kv) channels are clustered beneath the myelin sheath in regions immediately adjacent to paranodes, called juxtaparanodes, and along the inner mesaxon within the internode."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072181", "l": "mesonephric duct formation", "d": ["The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046193", "l": "anaerobic phenol-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0019674", "l": "NAD metabolic process", "d": ["The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1905066", "l": "regulation of canonical Wnt signaling pathway involved in heart development", "d": ["Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000916", "l": "negative regulation of glucuronoxylan catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoxylan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0002805", "l": "regulation of antimicrobial peptide biosynthetic process", "d": ["Any process that modulates the frequency, rate, or extent of antimicrobial peptide biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:0050975", "l": "sensory perception of touch", "d": ["The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030712", "l": "negative regulation of border follicle cell delamination", "d": ["Any process that decreases the frequency, rate or extent of border cell delamination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0034222", "l": "regulation of cell wall chitin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin in a cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044211", "l": "CTP salvage", "d": ["Any process which produces cytidine 5'-triphosphate (CTP) from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150191", "l": "positive regulation of interleukin-32 production", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-32 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000217", "l": "regulation of invasive growth in response to glucose limitation", "d": ["Any process that modulates the frequency, rate or extent of invasive growth in response to glucose limitation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098925", "l": "retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission", "d": ["Modulation of synaptic transmission by cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0010824", "l": "regulation of centrosome duplication", "d": ["Any process that modulates the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900951", "l": "negative regulation of 18-methylnonadec-1-ene biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.522719511813271", "identifiers": [{"i": "GO:0009581", "l": "detection of external stimulus", "d": ["The series of events in which an external stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003122", "l": "norepinephrine-mediated vasodilation", "d": ["A vasodilation process resulting from secretion of norepinephrine into the bloodstream or released by nerve endings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0002566", "l": "somatic diversification of immune receptors via somatic mutation", "d": ["The process in which immune receptor genes are diversified through somatic mutation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0000967", "l": "rRNA 5'-end processing", "d": ["Any process involved in forming the mature 5' end of an rRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1902570", "l": "protein localization to nucleolus", "d": ["A process in which a protein is transported to, or maintained in, a location within a nucleolus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.955962462590662", "identifiers": [{"i": "GO:0021700", "l": "developmental maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0090169", "l": "regulation of spindle assembly", "d": ["Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903443", "l": "cellular response to lipoic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044738", "l": "negative regulation of acid-sensing ion channel in another organism", "d": ["Any process in which an organism negatively regulates the activity of a voltage-gated sodium channel in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022027", "l": "interkinetic nuclear migration", "d": ["The movement of the nucleus of the ventricular zone cell between the apical and the basal zone surfaces. Mitosis occurs when the nucleus is near the apical surface, that is, the lumen of the ventricle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0052038", "l": "modulation by symbiont of host intracellular transport", "d": ["Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052710", "l": "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0031145", "l": "anaphase-promoting complex-dependent catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072193", "l": "ureter smooth muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006123", "l": "mitochondrial electron transport, cytochrome c to oxygen", "d": ["The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035072", "l": "ecdysone-mediated induction of salivary gland cell autophagic cell death", "d": ["Any process induced by ecdysone that directly activates salivary gland programmed cell death during salivary gland histolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098508", "l": "endothelial to hematopoietic transition", "d": ["The generation of hematopoietic stem cells from hemogenic endothelial cells by a process that includes tight-junction dissolution and loss of cell polarity followed by delamination from the endothelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900379", "l": "regulation of asperthecin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of asperthecin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903343", "l": "positive regulation of meiotic DNA double-strand break formation", "d": ["Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1900567", "l": "chanoclavine-I aldehyde metabolic process", "d": ["The chemical reactions and pathways involving chanoclavine-I aldehyde."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032689", "l": "negative regulation of type II interferon production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.572744119402742", "identifiers": [{"i": "GO:0050804", "l": "modulation of chemical synaptic transmission", "d": ["Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000787", "l": "regulation of venous endothelial cell fate commitment", "d": ["Any process that modulates the frequency, rate or extent of venous endothelial cell fate commitment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090548", "l": "response to nitrate starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nitrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002592", "l": "regulation of antigen processing and presentation via MHC class Ib", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0047496", "l": "vesicle transport along microtubule", "d": ["The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060036", "l": "notochord cell vacuolation", "d": ["The assembly and arrangement of a vacuole within a cell of the notochord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901438", "l": "negative regulation of toluene metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of toluene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:0019395", "l": "fatty acid oxidation", "d": ["The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0003231", "l": "cardiac ventricle development", "d": ["The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033490", "l": "cholesterol biosynthetic process via lathosterol", "d": ["The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003035", "l": "detection of increased carbon dioxide by carotid body chemoreceptor signaling", "d": ["The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in a carotid body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006860", "l": "extracellular amino acid transport", "d": ["The directed extracellular movement of amino acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:2000257", "l": "regulation of protein activation cascade", "d": ["Any process that modulates the frequency, rate or extent of protein activation cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000224", "l": "regulation of testosterone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of testosterone biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072256", "l": "metanephric glomerular mesangial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular mesangial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0052314", "l": "phytoalexin metabolic process", "d": ["The chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901813", "l": "astaxanthin metabolic process", "d": ["The chemical reactions and pathways involving astaxanthin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010399", "l": "rhamnogalacturonan I backbone metabolic process", "d": ["The chemical reactions and pathways involving the alternating alpha-(1->2)-linked rhamnose and alpha-(1->2)-linked B-galacturonic acid residues of the rhamnogalacturonan I backbone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010732", "l": "regulation of protein glutathionylation", "d": ["Any process that modulates the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.586422797268227", "identifiers": [{"i": "GO:0009908", "l": "flower development", "d": ["The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902196", "l": "isovaleryl-CoA(4-) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of isovaleryl-CoA(4-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021585", "l": "pons structural organization", "d": ["The process that contributes to the act of creating the structural organization of the pons. This process pertains to the physical shaping of a rudimentary structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002855", "l": "regulation of natural killer cell mediated immune response to tumor cell", "d": ["Any process that modulates the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0060602", "l": "branch elongation of an epithelium", "d": ["The growth process in which a branch increases in length from its base to its tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033689", "l": "negative regulation of osteoblast proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002451", "l": "peripheral B cell tolerance induction", "d": ["Tolerance induction of mature B cells in the peripheral lymphoid tissues: the blood, lymph nodes, spleen, and mucosal-associated lymphoid tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003330", "l": "regulation of extracellular matrix constituent secretion", "d": ["Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035990", "l": "tendon cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905271", "l": "regulation of proton-transporting ATP synthase activity, rotational mechanism", "d": ["Any process that modulates the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060959", "l": "cardiac neuron development", "d": ["The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048537", "l": "mucosa-associated lymphoid tissue development", "d": ["The process whose specific outcome is the progression of mucosal-associated lymphoid tissue over time, from its formation to the mature structure. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901101", "l": "gramicidin S metabolic process", "d": ["The chemical reactions and pathways involving gramicidin S."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:1902475", "l": "L-alpha-amino acid transmembrane transport", "d": ["The directed movement of L-alpha-amino acid across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014740", "l": "negative regulation of muscle hyperplasia", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hyperplasia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900992", "l": "(-)-secologanin metabolic process", "d": ["The chemical reactions and pathways involving (-)-secologanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0046637", "l": "regulation of alpha-beta T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of alpha-beta T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009139", "l": "pyrimidine nucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904069", "l": "ascaroside metabolic process", "d": ["The chemical reactions and pathways involving ascaroside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0045066", "l": "regulatory T cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires specialized features of a regulatory T cell. Regulatory T cells control or suppress immune responses through a variety of mechanisms and subsets include the CD4+CD25+ cell type as well as certain CD8+ cell types."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021677", "l": "rhombomere 8 formation", "d": ["The process that gives rise to rhombomere 8. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036514", "l": "dopaminergic neuron axon guidance", "d": ["The chemotaxis process that directs the migration of an axon growth cone of a dopaminergic neuron to a specific target site in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0032330", "l": "regulation of chondrocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of chondrocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009800", "l": "cinnamic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990976", "l": "protein transport along microtubule to mitotic spindle pole body", "d": ["The directed movement of a protein along a microtubule to the mitotic spindle pole body, mediated by motor proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0046457", "l": "prostanoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of prostanoids, any compound based on or derived from the prostanoate structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901253", "l": "negative regulation of intracellular transport of viral material", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intracellular transport of viral material."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0050981", "l": "detection of electrical stimulus", "d": ["The series of events by which an electrical stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0043523", "l": "regulation of neuron apoptotic process", "d": ["Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1905097", "l": "regulation of guanyl-nucleotide exchange factor activity", "d": ["Any process that modulates the frequency, rate or extent of guanyl-nucleotide exchange factor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021824", "l": "cerebral cortex tangential migration using cell-axon interactions", "d": ["The movement of cerebral cortex neuronal precursors tangentially through the cortex using interaction of the migrating cells with axons of other neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018984", "l": "naphthalenesulfonate metabolic process", "d": ["The chemical reactions and pathways involving naphthalenesulfonate, sulfonated derivatives of naphthalene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.394761313416218", "identifiers": [{"i": "GO:0031324", "l": "negative regulation of cellular metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000451", "l": "positive regulation of CD8-positive, alpha-beta T cell extravasation", "d": ["Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001146", "l": "positive regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048214", "l": "regulation of Golgi vesicle fusion to target membrane", "d": ["Any process that modulates the frequency, rate or extent of Golgi vesicle fusion to target membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904447", "l": "folate import across plasma membrane", "d": ["The directed movement of folic acid from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0031155", "l": "regulation of reproductive fruiting body development", "d": ["Any process that modulates the frequency, rate or extent of reproductive fruiting body development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0099551", "l": "trans-synaptic signaling by neuropeptide, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002918", "l": "negative regulation of peripheral B cell anergy", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell anergy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009594", "l": "detection of nutrient", "d": ["The series of events in which a nutrient stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1901073", "l": "glucosamine-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucosamine-containing compounds (glucosamines)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1904672", "l": "regulation of somatic stem cell population maintenance", "d": ["Any process that modulates the frequency, rate or extent of somatic stem cell population maintenance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061379", "l": "inferior colliculus development", "d": ["The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0072148", "l": "epithelial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into an epithelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001094", "l": "xylotriose transport", "d": ["The directed movement of a xylotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046119", "l": "7-methylguanosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036268", "l": "swimming", "d": ["Self-propelled movement of an organism from one location to another through water, often by means of active fin movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.537648571937247", "identifiers": [{"i": "GO:0006325", "l": "chromatin organization", "d": ["The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141029", "l": "disruption by symbiont of host focal adhesion", "d": ["The process by which a symbiont disupts host focal adhesion in its host."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061260", "l": "mesonephric mesangial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the mesonephros as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901433", "l": "positive regulation of response to cycloalkane", "d": ["Any process that activates or increases the frequency, rate or extent of response to cycloalkane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001153", "l": "positive regulation of renal water transport", "d": ["Any process that activates or increases the frequency, rate or extent of renal water transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039722", "l": "suppression by virus of host toll-like receptor signaling pathway", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of toll-like receptor (TLR) signaling in the host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0048745", "l": "smooth muscle tissue development", "d": ["The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032978", "l": "protein insertion into membrane from inner side", "d": ["The process in which a protein is incorporated into a lipid bilayer, e.g., the prokaryotic, mitochondrial, or chloroplast inner membrane, from the inner side."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.69776122844717", "identifiers": [{"i": "GO:0071824", "l": "protein-DNA complex organization", "d": ["Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046126", "l": "pyrimidine deoxyribonucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905653", "l": "positive regulation of artery morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of artery morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048496", "l": "maintenance of animal organ identity", "d": ["The process in which the identity of an animal organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901741", "l": "positive regulation of myoblast fusion", "d": ["Any process that activates or increases the frequency, rate or extent of myoblast fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042983", "l": "amyloid precursor protein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097624", "l": "UDP-galactose transmembrane import into Golgi lumen", "d": ["The directed movement of UDP-galactose into the Golgi lumen across the Golgi membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140874", "l": "paraherquonin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of paraherquonin, a meroterpenoid with a unique, highly congested hexacyclic molecular architecture."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904363", "l": "negative regulation of calcitonin secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcitonin secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0060411", "l": "cardiac septum morphogenesis", "d": ["The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0071270", "l": "1-butanol metabolic process", "d": ["The chemical reactions and pathways involving 1-butanol, an alkyl primary alcohol with the formula C4H10O."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045071", "l": "negative regulation of viral genome replication", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061950", "l": "negative regulation of premature acrosome loss", "d": ["Any process that stops, prevents or reduces the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001133", "l": "methane biosynthetic process from methanethiol", "d": ["The chemical reactions and pathways resulting in the formation of a methane from a methanethiol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034333", "l": "adherens junction assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0001706", "l": "endoderm formation", "d": ["The formation of the endoderm during gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.644186068201407", "identifiers": [{"i": "GO:0045937", "l": "positive regulation of phosphate metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039004", "l": "specification of pronephric proximal tubule identity", "d": ["The process in which the proximal tubule of the pronephric nephron acquires its identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150020", "l": "basal dendrite arborization", "d": ["The process in which the anatomical structures of a dendritic tree are generated on the basal neuron side and organized into dendritic branches."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160024", "l": "Leydig cell proliferation", "d": ["The multiplication or reproduction of Leydig cells, resulting in the expansion of a cell population. Leydig cells are interstitial cells located adjacent to the seminiferous tubules in the testis which produce testosterone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070785", "l": "negative regulation of growth of unicellular organism as a thread of attached cells", "d": ["Any process that decreases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035945", "l": "mitochondrial ncRNA surveillance", "d": ["The set of processes involved in identifying and degrading defective or aberrant non-coding RNA transcripts (ncRNAs) within the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034118", "l": "regulation of erythrocyte aggregation", "d": ["Any process that modulates the frequency, rate, or extent of erythrocyte aggregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071784", "l": "endoplasmic reticulum cisternal network assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0150077", "l": "regulation of neuroinflammatory response", "d": ["Any process that modulates the frequency, rate or extent of neuroinflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.029717311382392", "identifiers": [{"i": "GO:0040012", "l": "regulation of locomotion", "d": ["Any process that modulates the frequency, rate or extent of locomotion of a cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0097006", "l": "regulation of plasma lipoprotein particle levels", "d": ["Any process involved in the maintenance of internal levels of plasma lipoprotein particles within an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048651", "l": "polyphenic determination, influence by environmental factors", "d": ["The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0120029", "l": "proton export across plasma membrane", "d": ["The directed movement of hydrogen ions (protons) from inside a cell, across the plasma membrane and into the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140334", "l": "lipopolysaccharide localization to cell outer membrane", "d": ["A process in which a lipopolysaccharide is transported to the cell outer membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0030593", "l": "neutrophil chemotaxis", "d": ["The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051079", "l": "meiosis I nuclear membrane disassembly", "d": ["The controlled breakdown of the nuclear membranes during the first division of meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990349", "l": "gap junction-mediated intercellular transport", "d": ["The movement of substances between cells via gap junctions. A gap junction is a fine cytoplasmic channel, found in animal cells, that connects the cytoplasm of one cell to that of an adjacent cell, allowing ions and other molecules to pass freely between the two cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0120113", "l": "cytoplasm to vacuole transport by the NVT pathway", "d": ["A pathway targeting soluble cytosolic proteins to the vacuole lumen. It uses a selective autophagy receptor protein Nbr1, which is an ortholog of mammalian NBR1, and is remotely related to S. cerevisiae Cvt pathway receptor protein Atg19. Similar to the Cvt pathway, the cargos transported by this pathway are hydrolases, which presumably contribute to the hydrolytic activities in the vacuole lumen. Different from the Cvt pathway, this pathway does not require the macroautophagy machinery, but instead relies on the ESCRT machinery for cargo sequestration. This pathway is observed in the fission yeast S. pombe."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070488", "l": "neutrophil aggregation", "d": ["The adhesion of one neutrophil to one or more other neutrophils via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.473342453951815", "identifiers": [{"i": "GO:0006906", "l": "vesicle fusion", "d": ["Fusion of the membrane of a transport vesicle with its target membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901777", "l": "mitomycin C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mitomycin C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033465", "l": "cis-zeatin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1901402", "l": "negative regulation of tetrapyrrole metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0060457", "l": "negative regulation of digestive system process", "d": ["Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904827", "l": "negative regulation of hydrogen sulfide biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen sulfide biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110117", "l": "positive regulation of compound eye photoreceptor cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901693", "l": "negative regulation of compound eye retinal cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050862", "l": "positive regulation of T cell receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044479", "l": "envenomation resulting in modulation of mast cell degranulation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of blood mast cell degranulation in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010607", "l": "negative regulation of cytoplasmic mRNA processing body assembly", "d": ["Any process that decreases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903872", "l": "regulation of DNA recombinase mediator complex assembly", "d": ["Any process that modulates the frequency, rate or extent of DNA recombinase mediator complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051885", "l": "positive regulation of timing of anagen", "d": ["Any process that activates or increases the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900979", "l": "positive regulation of tatiopterin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of tatiopterin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902810", "l": "negative regulation of skeletal muscle fiber differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106042", "l": "negative regulation of GABA-A receptor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of GABA-A receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000476", "l": "positive regulation of opioid receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of opioid receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120277", "l": "positive regulation of cerebral blood circulation", "d": ["Any process that activates or increases the frequency, rate or extent of cerebral blood circulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021968", "l": "corticospinal neuron axon guidance through the internal capsule", "d": ["The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral cortex through the internal capsule in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901329", "l": "regulation of odontoblast differentiation", "d": ["Any process that modulates the frequency, rate or extent of odontoblast differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0106047", "l": "polyamine deacetylation", "d": ["The modification of acetylpolyamine by the removal of acetyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902080", "l": "regulation of calcium ion import into sarcoplasmic reticulum", "d": ["Any process that modulates the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0086026", "l": "atrial cardiac muscle cell to AV node cell signaling", "d": ["Any process that mediates the transfer of information from an atrial cardiomyocyte to an AV node cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052168", "l": "modulation by symbiont of defense-related host calcium-dependent protein kinase pathway", "d": ["Any process in which an organism modulates the frequency, rate or extent of the host calcium-dependent protein kinase signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0099566", "l": "regulation of postsynaptic cytosolic calcium ion concentration", "d": ["Any process that regulates the concentration of calcium in the postsynaptic cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045649", "l": "regulation of macrophage differentiation", "d": ["Any process that modulates the frequency, rate or extent of macrophage differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902385", "l": "glycyrrhetinate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycyrrhetinate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039015", "l": "cell proliferation involved in pronephros development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019051", "l": "induction by virus of host apoptotic process", "d": ["Any viral process that activates or increases the frequency, rate or extent of cell death by apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072269", "l": "metanephric long descending thin limb development", "d": ["The process whose specific outcome is the progression of the metanephric long descending thin limb over time, from its formation to the mature structure. The metanephric long descending thin limb is the descending thin limb of a long nephron in the metanephros that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900166", "l": "regulation of glial cell-derived neurotrophic factor production", "d": ["Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0048268", "l": "clathrin coat assembly", "d": ["The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070244", "l": "negative regulation of thymocyte apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032789", "l": "unsaturated monocarboxylic acid metabolic process", "d": ["The chemical reactions and pathways involving unsaturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and one or more unsaturated C-C bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071908", "l": "determination of intestine left/right asymmetry", "d": ["Determination of the asymmetric location of the intestine loops with respect to the left and right halves of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097102", "l": "endothelial tip cell fate specification", "d": ["The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904605", "l": "positive regulation of advanced glycation end-product receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of advanced glycation end-product receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0098927", "l": "vesicle-mediated transport between endosomal compartments", "d": ["A cellular transport process in which transported substances are moved in membrane-bounded vesicles between endosomal compartments, e.g, between early endosome and sorting endosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007119", "l": "budding cell isotropic bud growth", "d": ["Unlocalized bud growth such that the entire surface of the bud expands evenly, in a cell that reproduces by budding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.990900157612501", "identifiers": [{"i": "GO:0007620", "l": "copulation", "d": ["The act of sexual union between male and female, involving the transfer of sperm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060784", "l": "regulation of cell proliferation involved in tissue homeostasis", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.012343759826372", "identifiers": [{"i": "GO:0050982", "l": "detection of mechanical stimulus", "d": ["The series of events by which a mechanical stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0071632", "l": "optomotor response", "d": ["Eye, head or whole body movements that help to compensate movements of the environment in order to stabilize its image on the retina. In the case of whole body movements, these motor actions may also stabilize a locomotor course in response to some disturbance. Examples include: the optokinetic reflex, which allows human eyes to follow objects in motion while the head remains stationary reflex; the optomotor responses of flying insects and swimming fish."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007418", "l": "ventral midline development", "d": ["The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0072523", "l": "purine-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0001751", "l": "compound eye photoreceptor cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010335", "l": "response to non-ionic osmotic stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0048899", "l": "anterior lateral line development", "d": ["The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033866", "l": "nucleoside bisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002264", "l": "endothelial cell activation involved in immune response", "d": ["A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002361", "l": "CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048081", "l": "positive regulation of cuticle pigmentation", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098705", "l": "copper ion import across plasma membrane", "d": ["The directed movement of copper ions from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046386", "l": "deoxyribose phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001132", "l": "methane biosynthetic process from 3-(methylthio)propionic acid", "d": ["The chemical reactions and pathways resulting in the formation of a methane from a 3-(methylthio)propionic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080173", "l": "male-female gamete recognition during double fertilization forming a zygote and endosperm", "d": ["The initial contact step made between the male gamete and the female gamete during double fertilization forming a zygote and endosperm. An example can be found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901949", "l": "5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097051", "l": "establishment of protein localization to endoplasmic reticulum membrane", "d": ["The directed movement of a protein to a specific location in the endoplasmic reticulum membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0099120", "l": "socially cooperative development", "d": ["The process whose specific outcome is the progression of a non-reproductive fruiting body over time, from its formation to the mature structure. A non-reproductive fruiting body is a colonial multicellular structure consisting of co-operating unicellular organisms, some of which are spores. An example of such a process is found in Dictyostelium discoideum and Myxococcus xanthus colonies."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060768", "l": "regulation of epithelial cell proliferation involved in prostate gland development", "d": ["Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0046137", "l": "negative regulation of vitamin metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061880", "l": "regulation of anterograde axonal transport of mitochondrion", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019399", "l": "cyclohexanol oxidation", "d": ["The cyclohexanol metabolic process in which cyclohexanol is converted to adipate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0072490", "l": "toluene-containing compound metabolic process", "d": ["The chemical reactions and pathways involving toluene, methylbenzene (formula C7H8), or any of its derivatives."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018275", "l": "N-terminal peptidyl-cysteine acetylation", "d": ["The acetylation of the N-terminal cysteine of proteins to form the derivative N-acetyl-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.187744340883789", "identifiers": [{"i": "GO:0065003", "l": "protein-containing complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000901", "l": "cyclodextrin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a cyclodextrin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000456", "l": "negative regulation of T-helper 17 cell extravasation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:0010469", "l": "regulation of signaling receptor activity", "d": ["Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048801", "l": "antennal joint morphogenesis", "d": ["The process in which the anatomical structures of the antennal joint are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0001842", "l": "neural fold formation", "d": ["The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090691", "l": "formation of plant organ boundary", "d": ["The regionalization process that specifies plant organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.254170199969643", "identifiers": [{"i": "GO:0140013", "l": "meiotic nuclear division", "d": ["One of the two nuclear divisions that occur as part of the meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.37286743346295", "identifiers": [{"i": "GO:0032504", "l": "multicellular organism reproduction", "d": ["The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002657", "l": "positive regulation of tolerance induction to nonself antigen", "d": ["Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000406", "l": "positive regulation of T cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of T cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048386", "l": "positive regulation of retinoic acid receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of retinoic acid receptor signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0042819", "l": "vitamin B6 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140576", "l": "ascorbate homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of ascorbate at the level of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904538", "l": "regulation of glycolytic process through fructose-6-phosphate", "d": ["Any process that modulates the frequency, rate or extent of glycolytic process through fructose-6-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:0071675", "l": "regulation of mononuclear cell migration", "d": ["Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900266", "l": "negative regulation of substance P receptor binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of substance P receptor binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007144", "l": "female meiosis I", "d": ["The cell cycle process in which the first meiotic division occurs in the female germline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905151", "l": "negative regulation of voltage-gated sodium channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated sodium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0080175", "l": "phragmoplast microtubule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in phragmoplast, a plant cell specific structure that forms during late cytokinesis. Phragmoplast serves as a scaffold for cell plate assembly and subsequent formation of a new cell wall separating the two daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1905568", "l": "regulation of ferrichrome biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of ferrichrome biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.140992638571788", "identifiers": [{"i": "GO:0009891", "l": "positive regulation of biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050988", "l": "N-terminal peptidyl-methionine carboxylation", "d": ["The carboxylation of the N-terminal methionine of proteins to form the derivative N-carboxy-L-methionine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0032988", "l": "protein-RNA complex disassembly", "d": ["The disaggregation of a protein-RNA complex into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:1904888", "l": "cranial skeletal system development", "d": ["The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904504", "l": "positive regulation of lipophagy", "d": ["Any process that activates or increases the frequency, rate or extent of lipophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090279", "l": "regulation of calcium ion import", "d": ["Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035039", "l": "male pronucleus assembly", "d": ["The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000169", "l": "regulation of peptidyl-cysteine S-nitrosylation", "d": ["Any process that modulates the frequency, rate or extent of peptidyl-cysteine S-nitrosylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.527781272052167", "identifiers": [{"i": "GO:0009066", "l": "aspartate family amino acid metabolic process", "d": ["The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904589", "l": "regulation of protein import", "d": ["Any process that modulates the frequency, rate or extent of protein import."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097395", "l": "response to interleukin-32", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:2000431", "l": "regulation of cytokinesis, actomyosin contractile ring assembly", "d": ["Any process that modulates the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071255", "l": "Cvt vesicle assembly", "d": ["A vesicle organization process that takes place as part of the Cvt pathway, and results in the formation of a double membrane-bounded cytosolic structure that sequesters precursor aminopeptidase I (prAPI)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042941", "l": "D-alanine transport", "d": ["The directed movement of D-alanine, the D-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0160062", "l": "cutin-based cuticle development", "d": ["The process whose specific outcome is the progression of the cutin-based cuticle over time, from its formation to the mature structure. Cutin-based cuticle is an extracellular structure composed of a covalently linked macromolecular scaffold of cutin and a variety of organic solvent-soluble lipids that are collectively termed waxes. Such structures are found on the external face of polysaccharide cell walls in land plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905704", "l": "positive regulation of inhibitory synapse assembly", "d": ["Any process that activates or increases the frequency, rate or extent of inhibitory synapse assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110059", "l": "negative regulation of blood vessel endothelial cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006435", "l": "threonyl-tRNA aminoacylation", "d": ["The process of coupling threonine to threonyl-tRNA, catalyzed by threonyl-tRNA synthetase. The threonyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a threonine-accetping tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150090", "l": "multiple spine synapse organization, single dendrite", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and a single dendrite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903537", "l": "meiotic cell cycle process involved in oocyte maturation", "d": ["Any meiotic cell cycle process that is involved in oocyte maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0034391", "l": "regulation of smooth muscle cell apoptotic process", "d": ["Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.959969695995824", "identifiers": [{"i": "GO:0002250", "l": "adaptive immune response", "d": ["An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.783030043623796", "identifiers": [{"i": "GO:0001704", "l": "formation of primary germ layer", "d": ["The formation of the ectoderm, mesoderm and endoderm during gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0016082", "l": "synaptic vesicle priming", "d": ["A process that converts synaptic vesicles to a state of competence for calcium triggered fusion with the active zone membrane by bringing the two membranes into very close proximity. Priming typically (but not always) occurs after docking (Jahn and Fasshauer, 2012). Primed vesicles are also capable of spontaneously fusing with the active zone membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036178", "l": "filamentous growth of a population of unicellular organisms in response to neutral pH", "d": ["The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a neutral pH (pH close to 7) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061965", "l": "positive regulation of entry into reproductive diapause", "d": ["Any process that activates or increases the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0061045", "l": "negative regulation of wound healing", "d": ["Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006039", "l": "cell wall chitin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072043", "l": "regulation of pre-tubular aggregate formation by cell-cell signaling", "d": ["Any process that mediates the transfer of information from one cell to another that modulates the rate, frequency, or extent of pre-tubular aggregate formation. Pre-tubular aggregate formation is the cell adhesion process in which mesenchymal cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019745", "l": "pentacyclic triterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006021", "l": "inositol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007547", "l": "germ-line processes downstream of sex determination signal", "d": ["The events determining the germ-line sexual phenotype after the initial transmission of that phenotype to germ-line-specific information pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060407", "l": "negative regulation of penile erection", "d": ["Any process that stops, prevents, or reduces the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034135", "l": "regulation of toll-like receptor 2 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 2 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0045443", "l": "juvenile hormone secretion", "d": ["The regulated release of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035700", "l": "astrocyte chemotaxis", "d": ["The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042538", "l": "hyperosmotic salinity response", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035908", "l": "ventral aorta development", "d": ["The progression of the ventral aorta over time, from its initial formation to the mature structure. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044147", "l": "negative regulation of formation of structure involved in a symbiotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030725", "l": "germline ring canal formation", "d": ["Assembly of the cytoplasmic bridges between developing spermatogonial or oogonial cysts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046346", "l": "mannosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061098", "l": "positive regulation of protein tyrosine kinase activity", "d": ["Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062175", "l": "brexanolone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of brexanolone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0030500", "l": "regulation of bone mineralization", "d": ["Any process that modulates the frequency, rate or extent of bone mineralization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.470455508855807", "identifiers": [{"i": "GO:0007292", "l": "female gamete generation", "d": ["Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0015074", "l": "DNA integration", "d": ["The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140730", "l": "amphiregulin production", "d": ["The appearance of amphiregulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored precursor protein that can engage in juxtacrine signaling on adjacent cells. Alternatively, after proteolytic processing by cell membrane proteases, mainly TACE/ADAM17, AREG is secreted and behaves as an autocrine or paracrine factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061932", "l": "negative regulation of erythrocyte enucleation", "d": ["Any process that decreases the frequency, rate or extent of erythrocyte enucleation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106090", "l": "positive regulation of cell adhesion involved in sprouting angiogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032375", "l": "negative regulation of cholesterol transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032544", "l": "plastid translation", "d": ["The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000467", "l": "positive regulation of glycogen (starch) synthase activity", "d": ["Any process that activates or increases the frequency, rate or extent of glycogen (starch) synthase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0032508", "l": "DNA duplex unwinding", "d": ["The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002317", "l": "plasma cell differentiation", "d": ["The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061781", "l": "mitotic cohesin unloading", "d": ["Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA as part of the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.905555711669919", "identifiers": [{"i": "GO:0051608", "l": "histamine transport", "d": ["The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.781437354835234", "identifiers": [{"i": "GO:0045087", "l": "innate immune response", "d": ["Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043490", "l": "malate-aspartate shuttle", "d": ["The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0042331", "l": "phototaxis", "d": ["The directed movement of a motile cell or organism in response to light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901709", "l": "(+)-larreatricin metabolic process", "d": ["The chemical reactions and pathways involving (+)-larreatricin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010574", "l": "regulation of vascular endothelial growth factor production", "d": ["Any process that modulates the frequency, rate, or extent of production of vascular endothelial growth factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160070", "l": "intracellular borate homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of tetrahydroxoborate within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990895", "l": "regulation of protein localization to cell cortex of cell tip", "d": ["Any process that modulates the frequency, rate or extent of protein localization to cell cortex of cell tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0010374", "l": "stomatal complex development", "d": ["The process whose specific outcome is the progression of the stomatal complex over time from its formation to the mature structure. The stomatal complex is the stomatal guard cells and their associated epidermal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036060", "l": "slit diaphragm assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a slit diaphragm, specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0015712", "l": "hexose phosphate transport", "d": ["The directed movement of hexose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140380", "l": "psilocybin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of psilocybin, a psychotropic tryptamine-derived natural product."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140329", "l": "lysophospholipid translocation", "d": ["The movement of a lysophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060267", "l": "positive regulation of respiratory burst", "d": ["Any process that increases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902183", "l": "regulation of shoot apical meristem development", "d": ["Any process that modulates the frequency, rate or extent of shoot apical meristem development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044477", "l": "envenomation resulting in negative regulation of platelet aggregation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of platelet aggregation in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000059", "l": "negative regulation of ubiquitin-dependent protein catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-dependent protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009372", "l": "quorum sensing", "d": ["The cell-cell signaling process in which single-celled organisms carry out coordinated responses by monitoring their own population density, and often also that of other microbes, by producing small, diffusible, signal molecules, detecting the concentration of these molecules, and triggering a signal transduction pathway when a certain threshold is reached. Quorum sensing can occur amongst microbial communities in the environment or within host organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:0044501", "l": "modulation of signal transduction in another organism", "d": ["The process in which an organism effects a change in a signal transduction process - a cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell - in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044030", "l": "regulation of DNA methylation", "d": ["Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.378002841413903", "identifiers": [{"i": "GO:0035592", "l": "establishment of protein localization to extracellular region", "d": ["The directed movement of a protein to a specific location within the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900904", "l": "positive regulation of hexadecanal biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of hexadecanal biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0017038", "l": "protein import", "d": ["The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046117", "l": "queuosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904893", "l": "negative regulation of receptor signaling pathway via STAT", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of receptor signaling via STAT."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010031", "l": "circumnutation", "d": ["The organismal movement by which the tip of a plant organ follows a spiral pattern as a consequence of growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903063", "l": "negative regulation of reverse cholesterol transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of reverse cholesterol transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902066", "l": "regulation of cell wall pectin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cell wall pectin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002903", "l": "negative regulation of B cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0030808", "l": "regulation of nucleotide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0097272", "l": "ammonium homeostasis", "d": ["Any biological process involved in the maintenance of an internal steady state of ammonium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009204", "l": "deoxyribonucleoside triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.777964009505382", "identifiers": [{"i": "GO:0072078", "l": "nephron tubule morphogenesis", "d": ["The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090122", "l": "cholesterol ester hydrolysis involved in cholesterol transport", "d": ["The cholesterol metabolic process in which cholesterol esters are hydrolyzed into free fatty acids and cholesterol in the lysosome that contributes to intracellular cholesterol transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002552", "l": "serotonin secretion by mast cell", "d": ["The regulated release of serotonin by a mast cell or group of mast cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904050", "l": "positive regulation of spontaneous neurotransmitter secretion", "d": ["Any process that activates or increases the frequency, rate or extent of spontaneous neurotransmitter secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.675373588411375", "identifiers": [{"i": "GO:0050916", "l": "sensory perception of sweet taste", "d": ["The series of events required to receive a sweet taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048402", "l": "intermediate mesoderm structural organization", "d": ["The process that contributes to the act of creating the structural organization of the intermediate mesoderm. This process pertains to the physical shaping of a rudimentary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0071577", "l": "zinc ion transmembrane transport", "d": ["A process in which a zinc II ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009688", "l": "abscisic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060559", "l": "positive regulation of calcidiol 1-monooxygenase activity", "d": ["Any process that increases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0003382", "l": "epithelial cell morphogenesis", "d": ["The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046762", "l": "viral budding from endoplasmic reticulum membrane", "d": ["A viral budding that starts with formation of a membrane curvature in the host ER membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902000", "l": "homogentisate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of homogentisate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098968", "l": "neurotransmitter receptor transport postsynaptic membrane to endosome", "d": ["Vesicle-mediated transport of a neurotransmitter receptor complex from the postsynaptic membrane to the postsynaptic early endosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001549", "l": "cumulus cell differentiation", "d": ["The process in which a subpopulation of granulosa cells surrounding the oocyte acquires the specialized features of an ovarian cumulus cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042185", "l": "m-xylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of m-xylene, 1,3-dimethylbenzene, a colorless, liquid aromatic hydrocarbon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072137", "l": "condensed mesenchymal cell proliferation", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a condensed mesenchymal cell population. A condensed mesenchymal cell population is a population of adherent mesenchymal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0002450", "l": "B cell antigen processing and presentation", "d": ["The process in which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905458", "l": "positive regulation of lymphoid progenitor cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042532", "l": "negative regulation of tyrosine phosphorylation of STAT protein", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000981", "l": "negative regulation of inner ear receptor cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of inner ear receptor cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:1902358", "l": "sulfate transmembrane transport", "d": ["The directed movement of sulfate across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030813", "l": "positive regulation of nucleotide catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051939", "l": "gamma-aminobutyric acid import", "d": ["The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900519", "l": "negative regulation of response to pullulan", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to pullulan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014844", "l": "myoblast proliferation involved in skeletal muscle regeneration", "d": ["The multiplication or reproduction of myoblasts, resulting in the expansion of the cell population. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048742", "l": "regulation of skeletal muscle fiber development", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018184", "l": "protein polyamination", "d": ["The modification of a protein amino acid by polyamination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006346", "l": "DNA methylation-dependent heterochromatin formation", "d": ["Repression of transcription by methylation of DNA, leading to the formation of heterochromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032649", "l": "regulation of type II interferon production", "d": ["Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006009", "l": "glucose 1-phosphate phosphorylation", "d": ["The process of introducing a phosphate group into glucose 1-phosphate to produce glucose bisphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.995966292894806", "identifiers": [{"i": "GO:0051668", "l": "localization within membrane", "d": ["Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120057", "l": "regulation of small intestinal transit", "d": ["Any process that modulates the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031159", "l": "positive regulation of aggregate size involved in sorocarp development", "d": ["Any process that increases the size of the aggregate formed during sorocarp formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021861", "l": "forebrain radial glial cell differentiation", "d": ["The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009759", "l": "indole glucosinolate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000541", "l": "positive regulation of protein geranylgeranylation", "d": ["Any process that activates or increases the frequency, rate or extent of protein geranylgeranylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.426153789046865", "identifiers": [{"i": "GO:0007635", "l": "chemosensory behavior", "d": ["Behavior that is dependent upon the sensation of chemicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0072530", "l": "purine-containing compound transmembrane transport", "d": ["The process in which a purine-containing compound is transported across a membrane. A purine-containing compound is any compound that contains purine or a formal derivative thereof."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140965", "l": "secondary piRNA processing", "d": ["A process leading to the generation of a functional secondary piRNA, involving a self-perpetuating piRNA loop, often called the ping-pong cycle, in which piRNAs are amplified by pairing with complementary transcripts (for example the transposable element mRNA target). In Drosophila, the processing involves the piwi proteins aubergine and Argonaute 3 and in mice, the piwi proteins Piwil2 and Piwil4."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034058", "l": "endosomal vesicle fusion", "d": ["The homotypic fusion of endocytic vesicles to form or add to an early endosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060300", "l": "regulation of cytokine activity", "d": ["Any process that modulates the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0044691", "l": "tooth eruption", "d": ["The tooth development process in which the teeth enter the mouth and become visible."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018155", "l": "peptide cross-linking via sn-(2S,6R)-lanthionine", "d": ["The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of sn-(2S,6R)-lanthionine (meso-lanthione)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042852", "l": "L-alanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000097", "l": "sulfur amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060368", "l": "regulation of Fc receptor mediated stimulatory signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway.."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120329", "l": "protein localization to centriolar satellite", "d": ["A process in which a protein is transported to, or maintained in, a location within a centriolar satellite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051291", "l": "protein heterooligomerization", "d": ["The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035499", "l": "carnosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the dipeptide beta-alanyl-L-histidine (carnosine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052696", "l": "flavonoid glucuronidation", "d": ["The modification of a flavonoid by the conjugation of glucuronic acid. The resultant flavonoid glucuronosides are often much more water-soluble than the precursor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0010998", "l": "regulation of translational initiation by eIF2 alpha phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044616", "l": "modulation of relaxation of muscle in another organism", "d": ["The process in which an organism effects a change in the relaxation of muscle in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010663", "l": "positive regulation of striated muscle cell apoptotic process", "d": ["Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:2000142", "l": "regulation of DNA-templated transcription initiation", "d": ["Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031138", "l": "negative regulation of conjugation with cellular fusion", "d": ["Any process that decreases the rate or frequency of conjugation with cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0019666", "l": "nitrogenous compound fermentation", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of a nitrogen-containing compound, yielding energy in the form of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902436", "l": "negative regulation of male mating behavior", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of male mating behavior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0043060", "l": "meiotic metaphase I plate congression", "d": ["The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019450", "l": "L-cysteine catabolic process to pyruvate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including pyruvate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046325", "l": "negative regulation of glucose import", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0018143", "l": "nucleic acid-protein covalent cross-linking", "d": ["The formation of a covalent cross-link between a nucleic acid and a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0043545", "l": "molybdopterin cofactor metabolic process", "d": ["The chemical reactions and pathways involving the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099559", "l": "maintenance of alignment of postsynaptic density and presynaptic active zone", "d": ["The process by which alignment between postsynaptic density and presynaptic active zone is maintained."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071471", "l": "cellular response to non-ionic osmotic stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0140415", "l": "effector-mediated modulation of host defenses by symbiont", "d": ["A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905944", "l": "positive regulation of formation of growth cone in injured axon", "d": ["Any process that activates or increases the frequency, rate or extent of formation of growth cone in injured axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000152", "l": "regulation of ubiquitin-specific protease activity", "d": ["Any process that modulates the frequency, rate or extent of regulation of ubiquitin-specific protease activity (deubiquitinase) activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000321", "l": "positive regulation of T-helper 17 cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 17 cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046319", "l": "positive regulation of glucosylceramide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0043709", "l": "cell adhesion involved in single-species biofilm formation", "d": ["The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048905", "l": "anterior lateral line neuromast mantle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0015880", "l": "coenzyme A transport", "d": ["The directed movement of coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050821", "l": "protein stabilization", "d": ["Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904911", "l": "negative regulation of establishment of RNA localization to telomere", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of RNA localization to telomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048295", "l": "positive regulation of isotype switching to IgE isotypes", "d": ["Any process that activates or increases the frequency, rate or extent of isotype switching to IgE isotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035001", "l": "dorsal trunk growth, open tracheal system", "d": ["Growth of epithelial tubes that originate from pits in an open tracheal system and grow towards each other to meet and form a continuous open tube called the dorsal trunk. The dorsal trunk extends from the anterior spiracle to the posterior spiracle of the larva and forms the main airway of the insect tracheal system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902027", "l": "positive regulation of cartilage condensation", "d": ["Any process that activates or increases the frequency, rate or extent of cartilage condensation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030963", "l": "peptidyl-lysine dihydroxylation to 4,5-dihydroxy-L-lysine", "d": ["The dihydroxylation of peptidyl-lysine to peptidyl-4,5-dihydroxy-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042126", "l": "nitrate metabolic process", "d": ["The chemical reactions and pathways involving nitrates, inorganic or organic salts and esters of nitric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061767", "l": "negative regulation of lung blood pressure", "d": ["The process that decreases the force with which blood travels through the lungs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0015714", "l": "phosphoenolpyruvate transport", "d": ["The directed movement of phosphoenolpyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.240853996207278", "identifiers": [{"i": "GO:2000146", "l": "negative regulation of cell motility", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001091", "l": "nigerotriose transport", "d": ["The directed movement of a nigerotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1901970", "l": "positive regulation of mitotic sister chromatid separation", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid separation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901848", "l": "nicotinate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nicotinate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070398", "l": "wall teichoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072057", "l": "inner stripe development", "d": ["The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032636", "l": "interleukin-7 production", "d": ["The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006789", "l": "bilirubin conjugation", "d": ["The chemical reactions and pathways resulting in the formation of bilirubin monoglucuronide or bilirubin diglucuronide, water-soluble derivatives of bilirubin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007378", "l": "amnioserosa formation", "d": ["Formation of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. This occurs by the transformation of a narrow strip of cells at the dorsal midline of the blastoderm from columnar to squamous cells, accompanied by a lateral shift."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.871888620241165", "identifiers": [{"i": "GO:0030029", "l": "actin filament-based process", "d": ["Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097275", "l": "intracellular ammonium homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of ammonium within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1904600", "l": "mating projection actin fusion focus assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an actin fusion focus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.250759876326711", "identifiers": [{"i": "GO:0070293", "l": "renal absorption", "d": ["A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.108294271008795", "identifiers": [{"i": "GO:0098739", "l": "import across plasma membrane", "d": ["The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080177", "l": "plastoglobule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plastoglobule. Plastoglobule is a lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046968", "l": "peptide antigen transport", "d": ["The directed movement of a peptide antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.120403206680479", "identifiers": [{"i": "GO:0016310", "l": "phosphorylation", "d": ["The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0043696", "l": "dedifferentiation", "d": ["The process in which a specialized structure (cell, tissue or organ) loses structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these structures can revert back to the features of their ancestors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904192", "l": "regulation of cholangiocyte apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of cholangiocyte apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.871876592857262", "identifiers": [{"i": "GO:0031341", "l": "regulation of cell killing", "d": ["Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900272", "l": "negative regulation of long-term synaptic potentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of long-term synaptic potentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903713", "l": "asparagine transmembrane transport", "d": ["The directed movement of asparagine across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902953", "l": "positive regulation of ER to Golgi vesicle-mediated transport", "d": ["Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035998", "l": "7,8-dihydroneopterin 3'-triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 7,8-dihydroneopterin 3'-triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904227", "l": "negative regulation of glycogen synthase activity, transferring glucose-1-phosphate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0048308", "l": "organelle inheritance", "d": ["The partitioning of organelles between daughter cells at cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010635", "l": "regulation of mitochondrial fusion", "d": ["Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0009437", "l": "carnitine metabolic process", "d": ["The chemical reactions and pathways involving carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002273", "l": "plasmacytoid dendritic cell differentiation", "d": ["The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902222", "l": "erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of erythrose 4-phosphate/phosphoenolpyruvate family amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000414", "l": "negative regulation of fibronectin-dependent thymocyte migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fibronectin-dependent thymocyte migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0031620", "l": "regulation of fever generation", "d": ["Any process that modulates the rate or extent of fever generation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046786", "l": "viral replication complex formation and maintenance", "d": ["The process of organizing and assembling viral replication proteins in preparation for viral replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903602", "l": "thermospermine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of thermospermine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0046677", "l": "response to antibiotic", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0051262", "l": "protein tetramerization", "d": ["The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061155", "l": "pulmonary artery endothelial tube morphogenesis", "d": ["The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061555", "l": "ganglion structural organization", "d": ["The process that contributes to creating the structural organization of a ganglion. This process pertains to the physical shaping of a rudimentary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060794", "l": "leaflet morphogenesis", "d": ["The process in which the anatomical structures of the leaflet are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903432", "l": "regulation of TORC1 signaling", "d": ["Any process that modulates the frequency, rate or extent of TORC1 signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.523519163150823", "identifiers": [{"i": "GO:0030003", "l": "intracellular monoatomic cation homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of monoatomic cations within a cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.184249897008741", "identifiers": [{"i": "GO:0019220", "l": "regulation of phosphate metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903583", "l": "positive regulation of basophil degranulation", "d": ["Any process that activates or increases the frequency, rate or extent of basophil degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0042754", "l": "negative regulation of circadian rhythm", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048761", "l": "collenchyma cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a collenchyma cell. This is a plant cell in which the primary cell walls are unevenly thickened, with most thickening occurring at the cell corners. Cells are living and able to grow, they are elongated, and lignin and secondary walls absent. Collenchyma cells make up collenchyma tissue which acts as a supporting tissue in growing shoots, leaves and petioles. This tissue is often arranged in cortical ribs, as seen prominently in celery and rhubarb petioles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061584", "l": "orexin secretion", "d": ["The controlled release of orexin from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902322", "l": "regulation of methyl-branched fatty acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of methyl-branched fatty acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901516", "l": "aspyridone A metabolic process", "d": ["The chemical reactions and pathways involving aspyridone A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000229", "l": "regulation of pancreatic stellate cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of pancreatic stellate cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900397", "l": "regulation of pyrimidine nucleotide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of pyrimidine nucleotide biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904881", "l": "cellular response to hydrogen sulfide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0031056", "l": "regulation of histone modification", "d": ["Any process that modulates the frequency, rate or extent of the covalent alteration of a histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902087", "l": "dimethylsulfoniopropionate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of S,S-dimethyl-beta-propiothetin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1990942", "l": "mitotic metaphase chromosome recapture", "d": ["A mechanism to recapture 'lost' chromosomes (chromosomes which have become detached from the spindle) during metaphase of mitotic chromosome segregation. Chromosomes with unattached kinetochores are migrated along (non polar) spindle microtubules to the mitotic spindle pole body by a combination of microtubule depolymerisation and 'kinetochore sliding' (migration of the chromosome along the microtubule). The chromosome subsequently migrates along the polar spindle microtubule to the metaphase plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0006986", "l": "response to unfolded protein", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061475", "l": "cytosolic valyl-tRNA aminoacylation", "d": ["The process of coupling valine to valyl-tRNA in the cytosol, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0043268", "l": "positive regulation of potassium ion transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046046", "l": "TTP metabolic process", "d": ["The chemical reactions and pathways involving TTP, ribosylthymine triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.911912019781781", "identifiers": [{"i": "GO:0065009", "l": "regulation of molecular function", "d": ["Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072108", "l": "positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "d": ["Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002074", "l": "extraocular skeletal muscle development", "d": ["The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0009856", "l": "pollination", "d": ["The cascade of biological processes occurring in plants beginning when the pollen lands on the female reproductive organs of a plant and continuing up to, but not including, fertilization, as defined by sperm-egg cell fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045883", "l": "positive regulation of sulfur utilization", "d": ["Any process that activates or increases the frequency, rate or extent of sulfur utilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000743", "l": "nuclear migration involved in conjugation with cellular fusion", "d": ["The microtubule-based movement of nuclei towards one another as a prelude to karyogamy in organisms undergoing conjugation with cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.777124918050973", "identifiers": [{"i": "GO:0008544", "l": "epidermis development", "d": ["The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061890", "l": "positive regulation of astrocyte activation", "d": ["Any process that increases the frequency, rate or extent of astrocyte activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000951", "l": "methionine catabolic process to 3-methylthiopropanol", "d": ["The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanol is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903077", "l": "negative regulation of protein localization to plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048446", "l": "petal morphogenesis", "d": ["The process in which the anatomical structures of the petal are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031022", "l": "nuclear migration along microfilament", "d": ["The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902365", "l": "positive regulation of protein localization to spindle pole body", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990215", "l": "negative regulation by symbiont of host intracellular transport", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of intracellular transport in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061563", "l": "trigeminal ganglion structural organization", "d": ["The process that contributes to creating the structural organization of the trigeminal ganglion This process pertains to the physical shaping of a rudimentary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120073", "l": "negative regulation of pyloric antrum smooth muscle contraction", "d": ["Any process that decreases the frequency, rate or extent of any pyloric antrum smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.938395503300136", "identifiers": [{"i": "GO:0098813", "l": "nuclear chromosome segregation", "d": ["The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2000043", "l": "regulation of cardiac cell fate specification", "d": ["Any process that modulates the frequency, rate or extent of cardiac cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0060232", "l": "delamination", "d": ["The process of negative regulation of cell adhesion that results in a cell or sheet of cells splitting off from an existing epithelial sheet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001302", "l": "lipoxin A4 metabolic process", "d": ["The chemical reactions and pathways involving lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904730", "l": "negative regulation of intestinal lipid absorption", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intestinal lipid absorption."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903007", "l": "positive regulation of Lys63-specific deubiquitinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of Lys63-specific deubiquitinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080114", "l": "positive regulation of glycine hydroxymethyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of glycine hydroxymethyltransferase activity, the catalysis of the reaction 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1990950", "l": "metaphase/anaphase transition of meiosis II", "d": ["The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036415", "l": "regulation of tRNA stability", "d": ["Any process that modulates the propensity of transfer RNA (tRNA) molecules to degradation. Includes processes that both stabilize and destabilize tRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033198", "l": "response to ATP", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1901806", "l": "beta-glucoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-glucoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062166", "l": "negative regulation of pseudohyphal septin ring assembly", "d": ["Any process that decreases the rate, frequency or extent of pseudohyphal septin ring assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903413", "l": "cellular response to bile acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901472", "l": "regulation of Golgi calcium ion export", "d": ["Any process that modulates the frequency, rate or extent of Golgi calcium ion export."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046154", "l": "rhodopsin metabolic process", "d": ["The chemical reactions and pathways involving rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090260", "l": "negative regulation of retinal ganglion cell axon guidance", "d": ["Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044399", "l": "multi-species biofilm formation", "d": ["A process in which planktonically growing microorganisms of different species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007396", "l": "suture of dorsal opening", "d": ["Closure of the dorsal hole. Filopodia extending from each leading edge interdigitate at the dorsal midline and appear to prime the formation of adherens junctions between the two rows of leading edge cells. Newly formed septate junctions are also used to seal the dorsal hole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030204", "l": "chondroitin sulfate metabolic process", "d": ["The chemical reactions and pathways involving chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. They usually occur linked to a protein to form proteoglycans. Two subgroups exist, one in which the sulfate is on the 4-position (chondroitin sulfate A) and the second in which it is in the 6-position (chondroitin sulfate C). They often are polydisperse and often differ in the degree of sulfation from tissue to tissue. The chains of repeating disaccharide are covalently linked to the side chains of serine residues in the polypeptide backbone of a protein by a glycosidic attachment through the trisaccharide unit galactosyl-galactosyl-xylosyl. Chondroitin sulfate B is more usually known as dermatan sulfate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0097352", "l": "autophagosome maturation", "d": ["Removal of PI3P and Atg8/LC3 after the closure of the phagophore and before the fusion with the endosome/lysosome (e.g. mammals and insects) or vacuole (yeast), and that very likely destabilizes other Atg proteins and thus enables their efficient dissociation and recycling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.685364931984026", "identifiers": [{"i": "GO:0043632", "l": "modification-dependent macromolecule catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903258", "l": "sorbose import across plasma membrane", "d": ["The process in which sorbose is transported from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061100", "l": "lung neuroendocrine cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019429", "l": "fluorene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:2000191", "l": "regulation of fatty acid transport", "d": ["Any process that modulates the frequency, rate or extent of fatty acid transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060985", "l": "epicardium-derived cardiac vascular smooth muscle cell fate commitment", "d": ["The commitment of an epicardial cell to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901122", "l": "bacitracin A metabolic process", "d": ["The chemical reactions and pathways involving bacitracin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0048680", "l": "positive regulation of axon regeneration", "d": ["Any process that activates, maintains or increases the rate of axon regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021787", "l": "chemorepulsion of branchiomotor neuron axon in neural tube", "d": ["The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019329", "l": "ammonia oxidation", "d": ["The chemical reactions and pathways by which ammonia or ammonium is converted to molecular nitrogen or another nitrogen compound, with accompanying loss of electrons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.071082486141265", "identifiers": [{"i": "GO:0007034", "l": "vacuolar transport", "d": ["The directed movement of substances into, out of or within a vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0052029", "l": "disruption of host signal transduction pathway", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.892466024748572", "identifiers": [{"i": "GO:0061532", "l": "primary amine secretion, neurotransmission", "d": ["The regulated release of a primary amine by a cell, in which the primary amine acts as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0023022", "l": "termination of T cell signal transduction", "d": ["The signaling process in which T cell signal transduction is brought to an end rather than being reversibly modulated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001778", "l": "plasma membrane repair", "d": ["The resealing of a cell plasma membrane after cellular wounding due to, for instance, mechanical stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021614", "l": "glossopharyngeal nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006729", "l": "tetrahydrobiopterin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070238", "l": "activated T cell autonomous cell death", "d": ["A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen via the accumulation of pro-apoptotic gene products and decrease in anti-apoptotic gene products."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0048886", "l": "neuromast hair cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072535", "l": "tumor necrosis factor (ligand) superfamily member 11 production", "d": ["The appearance of tumor necrosis factor superfamily member 11 (TNFSF11; RANKL) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000236", "l": "negative regulation of tRNA processing", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900929", "l": "regulation of L-tyrosine import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of L-tyrosine import into the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903271", "l": "negative regulation of cytoplasmic translational elongation through polyproline stretches", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010094", "l": "specification of carpel identity", "d": ["The process in which a floral organ primordium acquires the carpel identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007078", "l": "lamin depolymerization", "d": ["The cell cycle process in which lamin is depolymerized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0150200", "l": "regulation of transport across blood-brain barrier", "d": ["Any process that modulates the frequency, rate or extent of transport across the blood-brain barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0021550", "l": "medulla oblongata development", "d": ["The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061191", "l": "positive regulation of vacuole fusion, non-autophagic", "d": ["Any process that increases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044631", "l": "positive regulation of complement activation, lectin pathway in another organism", "d": ["Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway, in a different organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000151", "l": "negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.316418070386277", "identifiers": [{"i": "GO:0007051", "l": "spindle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014735", "l": "regulation of muscle atrophy", "d": ["Any process that modulates the frequency, rate or extent of muscle atrophy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904249", "l": "negative regulation of age-related resistance", "d": ["Any process that stops, prevents or reduces the extent of age-related resistance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035383", "l": "thioester metabolic process", "d": ["The chemical reactions and pathways involving a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061080", "l": "right horn of sinus venosus development", "d": ["The progression of the right horn of the sinus venosus from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009098", "l": "leucine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160007", "l": "glutathione import into mitochondrion", "d": ["The process in which glutathione is transported from the cytosol into the mitochondrial matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097251", "l": "leukotriene B4 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0003263", "l": "cardioblast proliferation", "d": ["The multiplication or reproduction of cardioblasts, resulting in the expansion of the population in the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035494", "l": "SNARE complex disassembly", "d": ["The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904560", "l": "response to diphenidol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0051353", "l": "positive regulation of oxidoreductase activity", "d": ["Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0001541", "l": "ovarian follicle development", "d": ["The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:1903523", "l": "negative regulation of blood circulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003220", "l": "left ventricular cardiac muscle tissue morphogenesis", "d": ["The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070758", "l": "regulation of interleukin-35-mediated signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of an interleukin-35-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001177", "l": "negative regulation of mediator complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mediator complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900484", "l": "negative regulation of protein targeting to vacuolar membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090441", "l": "trehalose biosynthesis in response to heat stress", "d": ["The chemical reactions and pathways resulting in the formation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000970", "l": "tRNA exon ligation utilizing GTP as source of linkage phosphate", "d": ["A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous GTP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in the yeast Saccharomyces cerevisiae where the ligation reaction also produces a 2'-phosphate at the splice junction which is subsequently removed as part of the ligation process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070352", "l": "positive regulation of white fat cell proliferation", "d": ["Any process that activates or increases the rate or extent of white fat cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033357", "l": "L-arabinose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-arabinose, arabino-pentose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019570", "l": "L-arabinose catabolic process to 2-oxoglutarate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including 2-oxoglutarate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901377", "l": "organic heteropentacyclic compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of organic heteropentacyclic compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140009", "l": "L-aspartate import across plasma membrane", "d": ["The directed movement of L-aspartate from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905527", "l": "negative regulation of Golgi lumen acidification", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Golgi lumen acidification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901825", "l": "zeaxanthin metabolic process", "d": ["The chemical reactions and pathways involving zeaxanthin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019253", "l": "reductive pentose-phosphate cycle", "d": ["The fixation of carbon dioxide (CO2) as glucose in the chloroplasts of C3 plants; uses ATP and NADPH formed in the light reactions of photosynthesis; carbon dioxide reacts with ribulose 1,5-bisphosphate (catalyzed by the function of ribulose-bisphosphate carboxylase) to yield two molecules of 3-phosphoglycerate; these are then phosphorylated by ATP to 1,3-bisphosphateglyceraldehyde which, in turn, is then reduced by NADPH to glyceraldehyde 3-phosphate. The glyceraldehyde 3-phosphate is converted to fructose 5-phosphate and ribulose 5-phosphate by aldolase and other enzymes; the ribulose 5-phosphate is phosphorylated by ATP to ribulose 1,5-bisphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060025", "l": "regulation of synaptic activity", "d": ["Any process that modulates the frequency, rate or extent of synaptic activity, the controlled release of neurotransmitters into the synaptic cleft and their subsequent detection by a postsynaptic cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990273", "l": "snRNA capping", "d": ["The addition of a methylphosphate cap at the 5'-end of 7SK snRNA (7SK RNA). Capping 7SK RNA stabilizes it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010185", "l": "regulation of cellular defense response", "d": ["Any process that modulates the frequency, rate or extent of cellular defense response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903287", "l": "negative regulation of potassium ion import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion import across the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002574", "l": "thrombocyte differentiation", "d": ["The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010447", "l": "response to acidic pH", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0035932", "l": "aldosterone secretion", "d": ["The regulated release of aldosterone into the circulatory system. Aldosterone is a pregnane-based steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019322", "l": "pentose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044845", "l": "chain elongation of O-linked mannose residue", "d": ["Extension of the O-linked mannose residue of a mannoprotein by the stepwise addition of further mannose molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001143", "l": "N-methylnicotinate transport", "d": ["The directed movement of a N-methylnicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034769", "l": "basement membrane disassembly", "d": ["The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090516", "l": "L-serine transmembrane import into vacuole", "d": ["The directed movement of L-serine into the vacuole across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039536", "l": "negative regulation of RIG-I signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the RIG-I signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.426153789046865", "identifiers": [{"i": "GO:0006835", "l": "dicarboxylic acid transport", "d": ["The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901182", "l": "regulation of camalexin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of camalexin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046372", "l": "D-arabinose metabolic process", "d": ["The chemical reactions and pathways involving D-arabinose, the D-enantiomer of arabino-pentose. D-arabinose occurs in plant glycosides and is a constituent of arabinonucleosides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902210", "l": "positive regulation of bacterial-type flagellum assembly", "d": ["Any process that activates or increases the frequency, rate or extent of bacterial-type flagellum assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0007006", "l": "mitochondrial membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060829", "l": "negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation", "d": ["Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin in the anterior end of the neural plate. This regulation sets up a Wnt signaling gradient along the anterior/posterior axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901261", "l": "regulation of sorocarp spore cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of sorocarp spore cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905085", "l": "regulation of bioluminescence", "d": ["Any process that modulates the frequency, rate or extent of bioluminescence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035165", "l": "embryonic crystal cell differentiation", "d": ["The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0051382", "l": "kinetochore assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097092", "l": "polyacyltrehalose metabolic process", "d": ["The chemical reactions and pathways involving polyacyltrehalose, a pentaacylated, trehalose-based glycolipid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000994", "l": "regulation of mannan catabolic process", "d": ["Any process that modulates the frequency, rate or extent of mannan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010238", "l": "response to proline", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990114", "l": "RNA polymerase II core complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase II core complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043608", "l": "formamide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of formamide, the simplest amide, HCONH2, derived from formic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.605795807496975", "identifiers": [{"i": "GO:0051174", "l": "regulation of phosphorus metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0043113", "l": "receptor clustering", "d": ["The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006036", "l": "cuticle chitin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "44.754891186854344", "identifiers": [{"i": "GO:0048869", "l": "cellular developmental process", "d": ["A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0031280", "l": "negative regulation of cyclase activity", "d": ["Any process that stops or reduces the activity of a cyclase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072169", "l": "specification of posterior mesonephric tubule identity", "d": ["The process in which the tubules of the posterior mesonephros acquire their identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1990770", "l": "small intestine smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050888", "l": "determination of stimulus location", "d": ["The determination of where on the body surface, within the body or in the environment a stimulus originates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097114", "l": "NMDA glutamate receptor clustering", "d": ["The receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045060", "l": "negative thymic T cell selection", "d": ["The process of elimination of immature T cells in the thymus which react strongly with self-antigens."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051609", "l": "inhibition of neurotransmitter uptake", "d": ["Any process that prevents the activation of the directed movement of a neurotransmitter into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0035510", "l": "DNA dealkylation", "d": ["The removal of an alkyl group from one or more nucleotides within an DNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033352", "l": "UDP-D-apiose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-D-apiose, uridinediphosphoapicose, a substance composed of apiose in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045468", "l": "regulation of R8 cell spacing in compound eye", "d": ["Any process that ensures that the R8 cells are selected in a precise progressive pattern so that they are evenly spaced throughout the eye disc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014835", "l": "myoblast differentiation involved in skeletal muscle regeneration", "d": ["The process in which a relatively unspecialized satellite cell acquires specialized features of a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030887", "l": "positive regulation of myeloid dendritic cell activation", "d": ["Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046502", "l": "uroporphyrinogen III metabolic process", "d": ["The chemical reactions and pathways involving uroporphyrinogen III, a precursor for synthesis of vitamin B12, chlorophyll, and heme in organisms that produce these compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021684", "l": "cerebellar granular layer formation", "d": ["The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0008205", "l": "ecdysone metabolic process", "d": ["The chemical reactions and pathways involving ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects. It is the inactive prohormone of the moulting hormone ecdysterone and may have intrinsic hormonal activity at other stages of insect development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905561", "l": "positive regulation of kinetochore assembly", "d": ["Any process that activates or increases the frequency, rate or extent of kinetochore assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1900262", "l": "regulation of DNA-directed DNA polymerase activity", "d": ["Any process that modulates the frequency, rate or extent of DNA-directed DNA polymerase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.139845358389962", "identifiers": [{"i": "GO:0007163", "l": "establishment or maintenance of cell polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072682", "l": "eosinophil extravasation", "d": ["The migration of an eosinophil from the blood vessels into the surrounding tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031622", "l": "positive regulation of fever generation", "d": ["Any process that activates or increases the frequency, rate, or extent of fever generation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019376", "l": "galactolipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110052", "l": "toxic metabolite repair", "d": ["A cellular process that, through single- or multi-step enzymatic reactions, repairs toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903913", "l": "regulation of fusion of virus membrane with host plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of fusion of virus membrane with host plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903126", "l": "negative regulation of centriole-centriole cohesion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of centriole-centriole cohesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905639", "l": "positive regulation of mitochondrial mRNA catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of mitochondrial mRNA catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002258", "l": "positive regulation of kinin cascade", "d": ["Any process that activates or increases the frequency, rate, or extent of the kinin cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0090493", "l": "catecholamine uptake", "d": ["The directed movement of catecholamine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019567", "l": "arabinose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of arabinose, arabino-pentose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0016124", "l": "xanthophyll catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of xanthophylls, oxygen-containing carotenoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0051028", "l": "mRNA transport", "d": ["The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900367", "l": "positive regulation of defense response to insect", "d": ["Any process that activates or increases the frequency, rate or extent of defense response to insect."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070580", "l": "base J metabolic process", "d": ["The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The base is synthesized in a two-step pathway. Initially, a thymidine residue in DNA is hydroxylated by a thymidine hydroxylase (TH) to form the intermediate hydroxymethyluracil, which is then glucosylated to form base J."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:1901378", "l": "organic heteropentacyclic compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of organic heteropentacyclic compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097314", "l": "apoptosome assembly", "d": ["The aggregation, arrangement and bonding together of the apoptosome, a multisubunit protein complex involved in the signaling phase of the apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905141", "l": "negative regulation of apical ectodermal ridge formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070849", "l": "response to epidermal growth factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000841", "l": "negative regulation of dehydroepiandrosterone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dehydroepiandrosterone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903441", "l": "protein localization to ciliary membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within a ciliary membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001039", "l": "negative regulation of cellular response to drug", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to drug."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048914", "l": "myelination of anterior lateral line nerve axons", "d": ["The formation of compact myelin sheaths around the axons of the anterior lateral line nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002307", "l": "CD8-positive, alpha-beta regulatory T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta regulatory T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0075261", "l": "positive regulation of spore-bearing organ development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:1901861", "l": "regulation of muscle tissue development", "d": ["Any process that modulates the frequency, rate or extent of muscle tissue development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0016109", "l": "tetraterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0009061", "l": "anaerobic respiration", "d": ["The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902491", "l": "negative regulation of sperm capacitation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.626320336431576", "identifiers": [{"i": "GO:0015980", "l": "energy derivation by oxidation of organic compounds", "d": ["The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071641", "l": "negative regulation of macrophage inflammatory protein 1 alpha production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.235375449259656", "identifiers": [{"i": "GO:0034249", "l": "negative regulation of amide metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0051283", "l": "negative regulation of sequestering of calcium ion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031117", "l": "positive regulation of microtubule depolymerization", "d": ["Any process that activates or increases the frequency, rate or extent of microtubule depolymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071374", "l": "cellular response to parathyroid hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.516572991137522", "identifiers": [{"i": "GO:0002460", "l": "adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "d": ["An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002934", "l": "desmosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009126", "l": "purine nucleoside monophosphate metabolic process", "d": ["The chemical reactions and pathways involving purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "37.195788947340048", "identifiers": [{"i": "GO:0072175", "l": "epithelial tube formation", "d": ["The developmental process pertaining to the initial formation of an epithelial tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990831", "l": "cellular response to carcinoembryonic antigen", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carcinoembryonic antigen stimulus. The carcinoembryonic antigens represent a family of glycoproteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006618", "l": "SRP-dependent cotranslational protein targeting to membrane, signal sequence processing", "d": ["The removal of the signal peptide from a nascent protein during cotranslational membrane targeting."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046681", "l": "response to carbamate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031223", "l": "auditory behavior", "d": ["The behavior of an organism in response to a sound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048290", "l": "isotype switching to IgA isotypes", "d": ["The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:2000696", "l": "regulation of epithelial cell differentiation involved in kidney development", "d": ["Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015728", "l": "mevalonate transport", "d": ["The directed movement of mevalonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031999", "l": "negative regulation of fatty acid beta-oxidation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043537", "l": "negative regulation of blood vessel endothelial cell migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0001773", "l": "myeloid dendritic cell activation", "d": ["The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0002182", "l": "cytoplasmic translational elongation", "d": ["The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150158", "l": "positive regulation of interleukin-34 production", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-34 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046072", "l": "dTDP metabolic process", "d": ["The chemical reactions and pathways involving dTDP, deoxyribosylthymine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901507", "l": "negative regulation of acylglycerol transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of acylglycerol transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000412", "l": "histone peptidyl-prolyl isomerization", "d": ["The modification of a histone by cis-trans isomerization of a proline residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0007392", "l": "initiation of dorsal closure", "d": ["Events that occur at the start of dorsal closure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045719", "l": "negative regulation of glycogen biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019431", "l": "acetyl-CoA biosynthetic process from ethanol", "d": ["The chemical reactions and pathways resulting in the formation of acetyl-CoA from ethanol via acetaldehyde."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031949", "l": "regulation of glucocorticoid catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072228", "l": "metanephric prebend segment development", "d": ["The process whose specific outcome is the progression of the metanephric prebend segment over time, from its formation to the mature structure. The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0008617", "l": "guanosine metabolic process", "d": ["The chemical reactions and pathways involving guanine, guanine riboside, a nucleoside with a wide species distribution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035993", "l": "deltoid tuberosity development", "d": ["The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.675373588411375", "identifiers": [{"i": "GO:0097035", "l": "regulation of membrane lipid distribution", "d": ["Any process that modulates the proportions or spatial arrangement of lipids in a cellular membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000219", "l": "positive regulation of invasive growth in response to glucose limitation", "d": ["Any process that activates or increases the frequency, rate or extent of invasive growth in response to glucose limitation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021710", "l": "cerebellar stellate cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072056", "l": "pyramid development", "d": ["The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002314", "l": "germinal center B cell differentiation", "d": ["The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904867", "l": "protein localization to Cajal body", "d": ["A process in which a protein is transported to, or maintained in, a location within a Cajal body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0003070", "l": "regulation of systemic arterial blood pressure by neurotransmitter", "d": ["The regulation of blood pressure mediated by a neurotransmitter. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106164", "l": "positive regulation of exonucleolytic catabolism of deadenylated mRNA", "d": ["Any process that activates or increases the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072245", "l": "metanephric glomerular parietal epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072231", "l": "metanephric proximal convoluted tubule segment 1 development", "d": ["The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048073", "l": "regulation of eye pigmentation", "d": ["Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904957", "l": "negative regulation of midbrain dopaminergic neuron differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of midbrain dopaminergic neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046528", "l": "imaginal disc fusion", "d": ["The process following disc eversion whereby imaginal discs fuse with adjacent disc derivatives to form a continuous adult epidermis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009932", "l": "cell tip growth", "d": ["Growth that occurs specifically at the tip of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0055063", "l": "sulfate ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007406", "l": "negative regulation of neuroblast proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:1990173", "l": "protein localization to nucleoplasm", "d": ["A process in which a protein is transported to, or maintained in, a location within the nucleoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021849", "l": "neuroblast division in subventricular zone", "d": ["The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000811", "l": "negative regulation of anoikis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anoikis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000139", "l": "regulation of octopamine signaling pathway involved in response to food", "d": ["Any process that modulates the frequency, rate or extent of octopamine signaling pathway involved in response to food."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032210", "l": "regulation of telomere maintenance via telomerase", "d": ["Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046946", "l": "hydroxylysine metabolic process", "d": ["The chemical reactions and pathways involving hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid. Hydroxylysine is found in collagen and commonly has galactose and then glucose added sequentially by glycosyltransferases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901057", "l": "trimethylenediamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of trimethylenediamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002907", "l": "positive regulation of mature B cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate, or extent of mature B cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990959", "l": "eosinophil homeostasis", "d": ["The process of regulating the proliferation and elimination of eosinophils such that the total number of eosinophils within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060924", "l": "atrial cardiac muscle cell fate commitment", "d": ["The commitment of cells to atrial cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036147", "l": "rumination", "d": ["A digestive process in which food, usually grass or hay, is swallowed into a multi-compartmented stomach, regurgitated, chewed again, and swallowed again."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.878931644881824", "identifiers": [{"i": "GO:0019953", "l": "sexual reproduction", "d": ["A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160049", "l": "negative regulation of cGAS/STING signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cGAS/STING signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048300", "l": "negative regulation of isotype switching to IgD isotypes", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgD isotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901091", "l": "negative regulation of protein tetramerization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein tetramerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1905934", "l": "negative regulation of cell fate determination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0002295", "l": "T-helper cell lineage commitment", "d": ["The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper cell, a CD4-positive, alpha-beta T cell specialized to promote various immunological processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080003", "l": "thalianol metabolic process", "d": ["The chemical reactions and pathways involving the triterpene thalianol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0036446", "l": "myofibroblast differentiation", "d": ["The process in which an undifferentiated cell acquires the features of a myofibroblast cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0009709", "l": "terpenoid indole alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002814", "l": "negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0090697", "l": "post-embryonic plant organ morphogenesis", "d": ["Morphogenesis, during the post-embryonic phase, of a plant tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010443", "l": "meristemoid mother cell division", "d": ["The asymmetric cell division by which a meristemoid mother cells (MMC) give rise to a meristemoid and another cell. The other cell may itself become a MMC or may generate an epidermal cell. Any cell that undergoes this type of division is a MMC."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050784", "l": "cocaine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:1901379", "l": "regulation of potassium ion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1905874", "l": "regulation of postsynaptic density organization", "d": ["Any process that modulates the frequency, rate or extent of postsynaptic density organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120237", "l": "terminal acetylenic compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097086", "l": "amniotic stem cell differentiation", "d": ["The process whereby a relatively unspecialized cell acquires specialized features of an amniotic stem cell. An amniotic stem cell is a mesenchymal stem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue types such as skin, cartilage, cardiac tissue, nerves, muscle, and bone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904987", "l": "regulation of endothelial cell activation", "d": ["Any process that modulates the frequency, rate or extent of endothelial cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060744", "l": "mammary gland branching involved in thelarche", "d": ["The process in which the branching structure of the mammary gland duct is generated and organized during the period of sexual maturity in mammals. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090460", "l": "intracellular threonine homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of threonine within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048889", "l": "neuromast support cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:1902116", "l": "negative regulation of organelle assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000432", "l": "negative regulation of cytokinesis, actomyosin contractile ring assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.919132381084083", "identifiers": [{"i": "GO:0016192", "l": "vesicle-mediated transport", "d": ["A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030167", "l": "proteoglycan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905787", "l": "regulation of detection of mechanical stimulus involved in sensory perception of touch", "d": ["Any process that modulates the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.470950656012619", "identifiers": [{"i": "GO:0006475", "l": "internal protein amino acid acetylation", "d": ["The addition of an acetyl group to a non-terminal amino acid in a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0051259", "l": "protein complex oligomerization", "d": ["The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904266", "l": "regulation of Schwann cell chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of Schwann cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0062169", "l": "regulation of plus-end directed microtubule sliding", "d": ["Any process that mediates the frequency, rate, or extent of plus-end directed microtubule sliding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050943", "l": "negative regulation of iridophore differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of iridophore differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140982", "l": "detoxification of aluminum ion", "d": ["Any process that reduce or remove the toxicity of aluminum ions. These can include transport of the aluminum away from sensitive areas,  sequesteration, or chemical modification to an inert form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000451", "l": "rRNA 2'-O-methylation", "d": ["The addition of a methyl group to the 2'-oxygen atom of a nucleotide residue in an rRNA molecule during ribosome biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902326", "l": "positive regulation of chlorophyll biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of chlorophyll biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904910", "l": "regulation of establishment of RNA localization to telomere", "d": ["Any process that modulates the frequency, rate or extent of establishment of RNA localization to telomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0060911", "l": "cardiac cell fate commitment", "d": ["The commitment of cells to specific cardiac cell fates and their capacity to differentiate into cardiac cells. Cardiac cells are cells that comprise the organ which pumps blood through the circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060454", "l": "positive regulation of gastric acid secretion", "d": ["Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032023", "l": "trypsinogen activation", "d": ["The proteolytic processing of trypsinogen to the active form, trypsin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902037", "l": "negative regulation of hematopoietic stem cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039686", "l": "bidirectional double-stranded viral DNA replication", "d": ["A viral DNA replication process where replication occurs in both directions from the starting point. This creates two replication forks, moving in opposite directions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0052129", "l": "negative energy taxis", "d": ["The directed movement of a motile cell or organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0030952", "l": "establishment or maintenance of cytoskeleton polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099074", "l": "mitochondrion to lysosome transport", "d": ["Transport from the mitochondrion to the lysosome, mediated by mitochondrion-derived vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018911", "l": "1,2,4-trichlorobenzene metabolic process", "d": ["The chemical reactions and pathways involving 1,2,4-trichlorobenzene, a derivative of benzene with chlorine atoms attached to positions 1, 2 and 4 of the ring. It is a colorless liquid used as a solvent in chemical manufacturing, in dyes and intermediates, dielectric fluid, synthetic transformer oils, lubricants, heat-transfer medium and insecticides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0080021", "l": "response to benzoic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902439", "l": "cellular response to vanadate(3-)", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002858", "l": "regulation of natural killer cell mediated cytotoxicity directed against tumor cell target", "d": ["Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000174", "l": "regulation of pro-T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of pro-T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:1902882", "l": "regulation of response to oxidative stress", "d": ["Any process that modulates the frequency, rate or extent of response to oxidative stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019516", "l": "lactate oxidation", "d": ["The chemical reactions and pathways resulting in the conversion of lactate to other compounds, such as pyruvate, with concomitant loss of electrons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071294", "l": "cellular response to zinc ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001828", "l": "inner cell mass cellular morphogenesis", "d": ["The morphogenesis of cells in the inner cell mass."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904406", "l": "negative regulation of nitric oxide metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nitric oxide metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046281", "l": "cinnamic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cinnamic acid, 3-phenyl-2-propenoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901448", "l": "regulation of response to butan-1-ol", "d": ["Any process that modulates the frequency, rate or extent of response to butan-1-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0033151", "l": "V(D)J recombination", "d": ["The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0034104", "l": "negative regulation of tissue remodeling", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048381", "l": "lateral mesoderm structural organization", "d": ["The process that contributes to the act of creating the structural organization of the lateral mesoderm. This process pertains to the physical shaping of a rudimentary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009744", "l": "response to sucrose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "37.119340334016989", "identifiers": [{"i": "GO:0006810", "l": "transport", "d": ["The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002680", "l": "pro-T cell lineage commitment", "d": ["The process in which a lymphoid progenitor cell becomes committed to becoming a pro-T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051084", "l": "'de novo' post-translational protein folding", "d": ["The process of assisting in the correct noncovalent folding of newly formed polypeptides or folding intermediates of polypeptides that have exited the ribosome and/or have been stabilized and transferred by other chaperone proteins. This process could involve several cycles of ATP hydrolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072063", "l": "short descending thin limb development", "d": ["The process whose specific outcome is the progression of the short descending thin limb over time, from its formation to the mature structure. The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903670", "l": "regulation of sprouting angiogenesis", "d": ["Any process that modulates the frequency, rate or extent of sprouting angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048140", "l": "male germ-line cyst encapsulation", "d": ["Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the male gonad."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1904380", "l": "endoplasmic reticulum mannose trimming", "d": ["Any protein alpha-1,2-demannosylation that takes place in the endoplasmic reticulum quality control compartment (ERQC)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045605", "l": "negative regulation of epidermal cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070473", "l": "negative regulation of uterine smooth muscle contraction", "d": ["Any process that decreases the frequency, rate or extent of uterine smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072656", "l": "maintenance of protein location in mitochondrion", "d": ["Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0001783", "l": "B cell apoptotic process", "d": ["Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042200", "l": "cyanuric acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cyanuric acid, a potential degradation product of triazine herbicides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901143", "l": "insulin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of insulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006314", "l": "intron homing", "d": ["Lateral transfer of an intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044721", "l": "protein import into peroxisome matrix, substrate release", "d": ["The process by which the cargo protein is released into the peroxisomal matrix, following translocation across the membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.51677448868422", "identifiers": [{"i": "GO:1903522", "l": "regulation of blood circulation", "d": ["Any process that modulates the frequency, rate or extent of blood circulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905167", "l": "positive regulation of lysosomal protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of lysosomal protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000509", "l": "negative regulation of dendritic cell chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090102", "l": "cochlea development", "d": ["The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0032185", "l": "septin cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising septin complexes and their associated proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015899", "l": "aminotriazole transport", "d": ["The directed movement of aminotriazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminotriazole is an effective weed killer that also possesses some antithyroid activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0060428", "l": "lung epithelium development", "d": ["The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106081", "l": "maltose import across plasma membrane", "d": ["The directed movement of maltose from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901349", "l": "glucosinolate transport", "d": ["The directed movement of a glucosinolate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0034313", "l": "diol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061956", "l": "penetration of cumulus oophorus", "d": ["The infiltration by sperm of the cumulus oophorus to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900139", "l": "negative regulation of arachidonic acid secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of arachidonic acid secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000023", "l": "regulation of lateral root development", "d": ["Any process that modulates the frequency, rate or extent of lateral root development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014062", "l": "regulation of serotonin secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of serotonin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903839", "l": "positive regulation of mRNA 3'-UTR binding", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA 3'-UTR binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900745", "l": "positive regulation of p38MAPK cascade", "d": ["Any process that activates or increases the frequency, rate or extent of p38MAPK cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033372", "l": "establishment of protease localization to mast cell secretory granule", "d": ["The directed movement of a protease to a location within a secretory granule in a mast cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034316", "l": "negative regulation of Arp2/3 complex-mediated actin nucleation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "31.825613719575237", "identifiers": [{"i": "GO:0003008", "l": "system process", "d": ["A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140242", "l": "translation at postsynapse", "d": ["Translation that occurs at the postsynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0097376", "l": "interneuron axon guidance", "d": ["The process in which the migration of an axon growth cone of an interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. An interneuron is any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region, as contrasted with projection neurons which have axons projecting to other brain regions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035919", "l": "negative regulation of low voltage-gated calcium channel activity in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a low voltage-gated calcium channel in another organism. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106253", "l": "positive regulation of DNA strand resection involved in replication fork processing", "d": ["Any process that activates or increases the frequency, rate or extent of DNA strand resection involved in replication fork processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021928", "l": "basket cell precursor proliferation", "d": ["The multiplication or reproduction of neuroblasts that will give rise to basket cells. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900523", "l": "positive regulation of response to amylopectin", "d": ["Any process that activates or increases the frequency, rate or extent of response to amylopectin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071419", "l": "cellular response to amphetamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000070", "l": "regulation of response to water deprivation", "d": ["Any process that modulates the frequency, rate or extent of response to water deprivation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032743", "l": "positive regulation of interleukin-2 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-2 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015963", "l": "diadenosine triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072629", "l": "interleukin-28B production", "d": ["The appearance of interleukin-28B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051044", "l": "positive regulation of membrane protein ectodomain proteolysis", "d": ["Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0036092", "l": "phosphatidylinositol-3-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050889", "l": "determination of stimulus intensity", "d": ["The determination of the perceived strength of a sensory stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000367", "l": "regulation of acrosomal vesicle exocytosis", "d": ["Any process that modulates the frequency, rate or extent of acrosomal vesicle exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019121", "l": "peptidoglycan-protein cross-linking via N6-mureinyl-L-lysine", "d": ["The process of linking a protein to peptidoglycan via the epsilon amino group of lysine to the diaminopimelic acid of the peptidoglycan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046925", "l": "peptide cross-linking via 2-(S-L-cysteinyl)-D-phenylalanine", "d": ["The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-D-phenylalanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903788", "l": "positive regulation of glutathione biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of glutathione biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901062", "l": "guaiacyl lignin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of guaiacyl lignin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1905215", "l": "negative regulation of RNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014066", "l": "regulation of phosphatidylinositol 3-kinase signaling", "d": ["Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000452", "l": "regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation", "d": ["Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034140", "l": "negative regulation of toll-like receptor 3 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 3 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021645", "l": "vagus nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0050966", "l": "detection of mechanical stimulus involved in sensory perception of pain", "d": ["The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000741", "l": "positive regulation of mesenchymal stem cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905649", "l": "negative regulation of shell calcification", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of shell calcification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000886", "l": "glucuronoxylan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a glucuronoxylan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000011", "l": "regulation of adaxial/abaxial pattern formation", "d": ["Any process that modulates the frequency, rate or extent of adaxial/abaxial pattern formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904627", "l": "response to phorbol 13-acetate 12-myristate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.356257019993834", "identifiers": [{"i": "GO:2000026", "l": "regulation of multicellular organismal development", "d": ["Any process that modulates the frequency, rate or extent of multicellular organismal development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010213", "l": "non-photoreactive DNA repair", "d": ["A DNA repair process that is involved in repairing UV-induced DNA damage under non-photoreactivating conditions. The mechanism by which this repair process operates has not yet been completely elucidated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003145", "l": "embryonic heart tube formation via epithelial folding", "d": ["The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010271", "l": "regulation of chlorophyll catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of chlorophyll."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.118840318467207", "identifiers": [{"i": "GO:0003006", "l": "developmental process involved in reproduction", "d": ["A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900489", "l": "positive regulation of [2Fe-2S] cluster assembly", "d": ["Any process that activates or increases the frequency, rate or extent of [2Fe-2S] cluster assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000786", "l": "positive regulation of autophagosome assembly", "d": ["Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106218", "l": "galactosaminogalactan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactosaminogalactan. GAG is a heteropolysaccharide composed of alpha-1,4 linked galactose, N-acetyl galactosamine (GalNAc) and galactosamine (GalN)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060926", "l": "cardiac pacemaker cell development", "d": ["The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045646", "l": "regulation of erythrocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of erythrocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0035176", "l": "social behavior", "d": ["Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0045112", "l": "integrin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of integrins, a large family of transmembrane proteins that act as receptors for cell-adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904840", "l": "positive regulation of male germ-line stem cell asymmetric division", "d": ["Any process that activates or increases the frequency, rate or extent of male germ-line stem cell asymmetric division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000270", "l": "negative regulation of fibroblast apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0097009", "l": "energy homeostasis", "d": ["Any process involved in the balance between food intake (energy input) and energy expenditure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0032616", "l": "interleukin-13 production", "d": ["The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905643", "l": "positive regulation of DNA methylation", "d": ["Any process that activates or increases the frequency, rate or extent of DNA methylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902272", "l": "regulation of (R)-carnitine transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of (R)-carnitine transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019858", "l": "cytosine metabolic process", "d": ["The chemical reactions and pathways involving cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097703", "l": "cellular response to pulsatile fluid shear stress", "d": ["Any response to pulsatile fluid shear stress that occurs at the level of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.594043123901756", "identifiers": [{"i": "GO:0030111", "l": "regulation of Wnt signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0000463", "l": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018228", "l": "peptidyl-S-geranylgeranyl-L-cysteine biosynthetic process from peptidyl-cysteine", "d": ["The modification of peptidyl-cysteine to form peptidyl-S-geranylgeranylcysteine; formation of S-geranylgeranyl-L-cysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CAAX motif and methyl esterification of the geranylgeranylated cysteine; methyl esterification but not cleavage occurs for the CXC motif. For the type II geranylgeranyltransferase the residue may be found at the first and final positions in the sequence motif C-X-C* or at the final position in the sequence motif C-C*. These motifs are necessary but not sufficient for modification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062112", "l": "fatty acid primary amide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a fatty acid primary amide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060672", "l": "epithelial cell morphogenesis involved in placental branching", "d": ["The change in form (cell shape and size) that occurs when a trophoblast cell elongates to contribute to the branching of the placenta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021970", "l": "corticospinal neuron axon guidance through the basilar pons", "d": ["The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral peduncle through the basilar pons in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070194", "l": "synaptonemal complex disassembly", "d": ["The controlled breakdown of a synaptonemal complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030592", "l": "DNA ADP-ribosylation", "d": ["The covalent attachment of an ADP-ribosyl group to a residue in double-stranded DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0006140", "l": "regulation of nucleotide metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120075", "l": "positive regulation of endocardial cushion cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of endocardial cushion cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018400", "l": "peptidyl-proline hydroxylation to 3-hydroxy-L-proline", "d": ["The modification of peptidyl-proline to form 3-hydroxy-L-proline; catalyzed by procollagen-proline 3-dioxygenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060684", "l": "epithelial-mesenchymal cell signaling", "d": ["Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904256", "l": "positive regulation of iron ion transmembrane transporter activity", "d": ["Any process that activates or increases the frequency, rate or extent of an iron transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120071", "l": "regulation of pyloric antrum smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of any pyloric antrum smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042149", "l": "cellular response to glucose starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901423", "l": "response to benzene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzene stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0002360", "l": "T cell lineage commitment", "d": ["The process in which a lymphoid progenitor cell becomes committed to becoming any type of T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0042438", "l": "melanin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036316", "l": "SREBP-SCAP complex retention in endoplasmic reticulum", "d": ["Any process in which the SREBP-SCAP complex is maintained in the endoplasmic reticulum and prevented from moving elsewhere. The SREBP-SCAP complex is formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP). In the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed. In the presence of sterols, the complex binds ER-resident proteins such as INSIG, which retain the complex in the ER."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0062109", "l": "regulation of DNA recombinase disassembly", "d": ["Any process that modulates the rate, frequency or extent of DNA recombinase disassembly, the disaggregation of a DNA recombinase complex into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0015916", "l": "fatty-acyl-CoA transport", "d": ["The directed movement of fatty acyl coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acyl coenzyme A is an acyl group linked to 3'-phosphoadenosine-(5')diphospho(4')pantatheine (coenzyme A)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903640", "l": "negative regulation of gastrin-induced gastric acid secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gastrin-induced gastric acid secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.760368348201226", "identifiers": [{"i": "GO:0072359", "l": "circulatory system development", "d": ["The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075307", "l": "positive regulation of conidium formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052697", "l": "xenobiotic glucuronidation", "d": ["The modification of a xenobiotic substance by the conjugation of glucuronic acid. The resultant glucuronosides are often much more water-soluble than the xenobiotic precursor, enabling efficient excretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0050917", "l": "sensory perception of umami taste", "d": ["The series of events required to receive an umami taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates. This is a neurological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010862", "l": "positive regulation of pathway-restricted SMAD protein phosphorylation", "d": ["Any process that increases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900844", "l": "negative regulation of monodictyphenone biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of monodictyphenone biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0090235", "l": "regulation of metaphase plate congression", "d": ["Any process that modulates the rate, frequency, or extent of metaphase plate congression, the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0032074", "l": "negative regulation of nuclease activity", "d": ["Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0089722", "l": "phosphoenolpyruvate transmembrane transport", "d": ["The directed movement of phosphoenolpytuvate across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038019", "l": "Wnt receptor recycling", "d": ["The process that results in the return of a Wnt receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive a Wnt signal. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.805366613539277", "identifiers": [{"i": "GO:0014046", "l": "dopamine secretion", "d": ["The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0016242", "l": "negative regulation of macroautophagy", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032016", "l": "negative regulation of Ran protein signal transduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Ran protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046600", "l": "negative regulation of centriole replication", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of centriole replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061266", "l": "mesonephric interstitial fibroblast differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the mesonephros as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061303", "l": "cornea development in camera-type eye", "d": ["The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0002714", "l": "positive regulation of B cell mediated immunity", "d": ["Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007521", "l": "muscle cell fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into a muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071688", "l": "striated muscle myosin thick filament assembly", "d": ["The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in striated muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110080", "l": "positive regulation of placenta blood vessel development", "d": ["Any process that activates or increases the frequency, rate or extent of placenta blood vessel development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000958", "l": "negative regulation of cyclodextrin catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cyclodextrin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032949", "l": "regulation of alpha-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of alpha-glucans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0003097", "l": "renal water transport", "d": ["The directed movement of water (H2O) by the renal system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904862", "l": "inhibitory synapse assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an inhibitory synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:1904018", "l": "positive regulation of vasculature development", "d": ["Any process that activates or increases the frequency, rate or extent of vasculature development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003064", "l": "regulation of heart rate by hormone", "d": ["The process in which the hormones modulates the rate of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106394", "l": "negative regulation of palmitic acid catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a palmitic acid catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904275", "l": "tricellular tight junction disassembly", "d": ["The disaggregation of a tricellular tight junction into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903003", "l": "positive regulation of protein deubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein deubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.871876592857262", "identifiers": [{"i": "GO:0007552", "l": "metamorphosis", "d": ["A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033658", "l": "modification by symbiont of host chloroplast thylakoid", "d": ["The process in which an organism effects a change in the structure or function of the host cell chloroplast thylakoid. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044512", "l": "envenomation resulting in modulation of glucagon-like peptide receptor 1 activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of glucagon-like peptide receptor 1 activity in of the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072314", "l": "glomerular epithelial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905840", "l": "positive regulation of telomeric D-loop disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of telomeric D-loop disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045829", "l": "negative regulation of isotype switching", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0046374", "l": "teichoic acid metabolic process", "d": ["The chemical reactions and pathways involving teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150064", "l": "vertebrate eye-specific patterning", "d": ["Early postnatal vertebrate developmental process, during which axons of retinal ganglion cells (RGCs), transmitting overlapping inputs from both eyes, segregate into distinct eye-specific non-overlapping regions in the dorsal lateral geniculate nucleus (dLGN) of the thalamus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:1905132", "l": "regulation of meiotic chromosome separation", "d": ["Any process that modulates the frequency, rate or extent of meiotic chromosome separation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901571", "l": "fatty acid derivative transport", "d": ["The directed movement of a fatty acid derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000374", "l": "regulation of oxygen metabolic process", "d": ["Any process that modulates the frequency, rate or extent of oxygen metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901849", "l": "nicotinate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotinate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0060795", "l": "cell fate commitment involved in formation of primary germ layer", "d": ["The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014865", "l": "detection of activity", "d": ["The series of events in which an activity stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021631", "l": "optic nerve morphogenesis", "d": ["The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0051170", "l": "import into nucleus", "d": ["The directed movement of substances into the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904245", "l": "regulation of polynucleotide adenylyltransferase activity", "d": ["Any process that modulates the frequency, rate or extent of polynucleotide adenylyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071239", "l": "cellular response to streptomycin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902236", "l": "negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007356", "l": "thorax and anterior abdomen determination", "d": ["Specification of the central (trunk) regions of the embryo by the gap genes; exemplified in insects by the actions of the Kruppel gene product."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0090177", "l": "establishment of planar polarity involved in neural tube closure", "d": ["Coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0022010", "l": "central nervous system myelination", "d": ["The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030253", "l": "protein secretion by the type I secretion system", "d": ["The process in which proteins are secreted into the extracellular milieu via the type I secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002492", "l": "peptide antigen assembly with MHC class Ib protein complex", "d": ["The binding of a peptide antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003173", "l": "ventriculo bulbo valve development", "d": ["The progression of the ventriculo bulbo valve over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048550", "l": "negative regulation of pinocytosis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0044576", "l": "pentose catabolic process to ethanol", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbons, where one of the resulting products is ethanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905834", "l": "response to pyrimidine ribonucleotide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900615", "l": "emericellamide A metabolic process", "d": ["The chemical reactions and pathways involving emericellamide A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904370", "l": "regulation of protein localization to actin cortical patch", "d": ["Any process that modulates the frequency, rate or extent of protein localization to actin cortical patch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901318", "l": "negative regulation of flagellated sperm motility", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0048368", "l": "lateral mesoderm development", "d": ["The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900210", "l": "positive regulation of cardiolipin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cardiolipin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000777", "l": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia", "d": ["Any positive regulation of proteasomal ubiquitin-dependent protein catabolic process that is involved in a cellular response to hypoxia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904100", "l": "positive regulation of protein O-linked glycosylation", "d": ["Any process that activates or increases the frequency, rate or extent of protein O-linked glycosylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070217", "l": "transcription factor TFIIIB complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a transcription factor TFIIIB complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001101", "l": "maltopentaose transport", "d": ["The directed movement of a maltopentaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1901889", "l": "negative regulation of cell junction assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0043452", "l": "cellular alkyne metabolic process", "d": ["The chemical reactions and pathways involving an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2, as carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.232064878529073", "identifiers": [{"i": "GO:0009081", "l": "branched-chain amino acid metabolic process", "d": ["The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "46.024622519302952", "identifiers": [{"i": "GO:0019222", "l": "regulation of metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0062035", "l": "sensory perception of cold stimulus", "d": ["The series of events required for an organism to receive a cold temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018982", "l": "vanillin metabolic process", "d": ["The chemical reactions and pathways involving vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods and can be obtained as a by-product of the pulp and paper industry by the oxidative breakdown of lignin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070715", "l": "sodium-dependent organic cation transport", "d": ["The directed, sodium-dependent, movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071787", "l": "endoplasmic reticulum tubular network formation", "d": ["The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0040003", "l": "chitin-based cuticle development", "d": ["Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0016487", "l": "farnesol metabolic process", "d": ["The chemical reactions and pathways involving the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002672", "l": "positive regulation of B cell anergy", "d": ["Any process that activates or increases the frequency, rate, or extent of B cell anergy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018000", "l": "N-terminal peptidyl-tyrosine acetylation", "d": ["The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900748", "l": "positive regulation of vascular endothelial growth factor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036145", "l": "dendritic cell homeostasis", "d": ["The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006226", "l": "dUMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dUMP, deoxyuridine monophosphate (2'-deoxyuridine 5'-phosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048132", "l": "female germ-line stem cell asymmetric division", "d": ["The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018227", "l": "peptidyl-S-12-hydroxyfarnesyl-L-cysteine biosynthetic process from peptidyl-cysteine", "d": ["The modification of peptidyl-cysteine to form S-12-hydroxyfarnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002309", "l": "T cell proliferation involved in immune response", "d": ["The expansion of a T cell population by cell division as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1990183", "l": "lymphatic vascular process in circulatory system", "d": ["A circulatory process that occurs at the level of the lymphatic vasculature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901685", "l": "glutathione derivative metabolic process", "d": ["The chemical reactions and pathways involving glutathione derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900977", "l": "regulation of tatiopterin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of tatiopterin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0032377", "l": "regulation of intracellular lipid transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021740", "l": "principal sensory nucleus of trigeminal nerve development", "d": ["The process whose specific outcome is the progression of the pontine nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021925", "l": "cerebellar Purkinje cell precursor proliferation", "d": ["The multiplication or reproduction of neuroblasts that will give rise to Purkinje cells. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0003197", "l": "endocardial cushion development", "d": ["The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905522", "l": "negative regulation of macrophage migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002796", "l": "positive regulation of antimicrobial peptide secretion", "d": ["Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048021", "l": "regulation of melanin biosynthetic process", "d": ["Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071314", "l": "cellular response to cocaine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0072491", "l": "toluene-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of toluene, methylbenzene (formula C7H8), or any of its derivatives."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0035684", "l": "helper T cell extravasation", "d": ["The migration of a helper T cell from the blood vessels into the surrounding tissue. A helper T-cell is an effector T cell that provides help in the form of secreted cytokines to other immune cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0086055", "l": "Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling", "d": ["The process that mediates signaling interactions between a Purkinje myocyte and a ventricular cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039638", "l": "lipopolysaccharide-mediated virion attachment to host cell", "d": ["The process by which a virion attaches to a host cell by binding to a lipopolysaccharide (LPS) on the host cell surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1905879", "l": "regulation of oogenesis", "d": ["Any process that modulates the frequency, rate or extent of oogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033684", "l": "regulation of luteinizing hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901946", "l": "miltiradiene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of miltiradiene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0009737", "l": "response to abscisic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0046470", "l": "phosphatidylcholine metabolic process", "d": ["The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061425", "l": "positive regulation of ethanol catabolic process by positive regulation of transcription from RNA polymerase II promoter", "d": ["Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of an ethanol catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070358", "l": "actin polymerization-dependent cell motility", "d": ["A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140298", "l": "endocytic iron import into cell", "d": ["Uptake of iron into a cell via binding to an extracellular receptor, which is internalized by endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042275", "l": "error-free postreplication DNA repair", "d": ["The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA via processes such as template switching, which does not remove the replication-blocking lesions but does not increase the endogenous mutation rate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002256", "l": "regulation of kinin cascade", "d": ["Any process that modulates the frequency, rate, or extent of the kinin cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:1903351", "l": "cellular response to dopamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050968", "l": "detection of chemical stimulus involved in sensory perception of pain", "d": ["The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072298", "l": "regulation of metanephric glomerulus development", "d": ["Any process that modulates the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0042078", "l": "germ-line stem cell division", "d": ["The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099585", "l": "release of sequestered calcium ion into presynaptic cytosol", "d": ["The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the presynaptic cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0009620", "l": "response to fungus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045006", "l": "DNA deamination", "d": ["The removal of an amino group from a nucleotide base in DNA. An example is the deamination of cytosine to produce uracil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:1990869", "l": "cellular response to chemokine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060007", "l": "linear vestibuloocular reflex", "d": ["A vestibular reflex by which a response to a linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the otolith and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000253", "l": "positive regulation of feeding behavior", "d": ["Any process that activates or increases the frequency, rate or extent of feeding behavior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0034969", "l": "histone arginine methylation", "d": ["The modification of a histone by addition of a methyl group to an arginine residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044074", "l": "negative regulation by symbiont of host translation", "d": ["The process in which a symbiont organism stops, prevents, or reduces the frequency, rate or extent of translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072581", "l": "protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine", "d": ["The modification of an N6-(lysyl)-L-lysine residue in a protein, producing protein-N6-(beta-lysyl)-L-lysine ((2S)-2-amino-6-([(2S)-2,6-diaminohexanoyl]amino)hexanoic acid). This modification is observed in, and is probably unique to, translation elongation factor P (EF-P)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046684", "l": "response to pyrethroid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrethroid stimulus. Pyrethroids are a group of growth regulators, analogous to insect juvenile hormones, that interfere with the development of insect larvae and are used in the control of insects that are harmful in the adult stage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0007380", "l": "specification of segmental identity, head", "d": ["The specification of the characteristic structures of the head segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030398", "l": "peroxisomal membrane disassembly", "d": ["The controlled breakdown of the membranes of cargo-carrying vesicles formed during peroxisome degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071693", "l": "protein transport within extracellular region", "d": ["The directed movement of proteins in the extracellular region, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044524", "l": "protein sulfhydration", "d": ["The modification of a protein amino acid by the addition of sulfur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120161", "l": "regulation of cold-induced thermogenesis", "d": ["Any process that modulates the frequency, rate or extent of cold-induced thermogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010076", "l": "maintenance of floral meristem identity", "d": ["The process in which an organism retains a population of floral meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039634", "l": "killing by virus of host cell during superinfection exclusion", "d": ["The viral-killing of a host cell by a pre-existing virus in response to a subsequent infection of the host cell by second virus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034147", "l": "regulation of toll-like receptor 5 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 5 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0007448", "l": "anterior/posterior pattern specification, imaginal disc", "d": ["The establishment, maintenance and elaboration of the anterior/posterior axis of the imaginal disc. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that rapidly develop into adult appendages during metamorphosis from larval to adult form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033369", "l": "establishment of protein localization to mast cell secretory granule", "d": ["The directed movement of a protein to a location within a secretory granule in a mast cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905938", "l": "positive regulation of germ cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of germ cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001682", "l": "tRNA 5'-leader removal", "d": ["Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009693", "l": "ethylene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902347", "l": "response to strigolactone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070903", "l": "mitochondrial tRNA thio-modification", "d": ["The addition a sulfur atom to a nucleotide in a mitochondrial tRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044357", "l": "regulation of rRNA stability", "d": ["Any process that modulates the propensity of rRNA molecules to degradation. Includes processes that both stabilize and destabilize rRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060568", "l": "regulation of peptide hormone processing", "d": ["Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903232", "l": "melanosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010145", "l": "fructan metabolic process", "d": ["The chemical reactions and pathways involving fructan, a polysaccharide consisting of fructose residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002405", "l": "antigen sampling by dendritic cells in mucosal-associated lymphoid tissue", "d": ["The process of antigen sampling carried out by dendritic cells in the mucosal-associated lymphoid tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0006903", "l": "vesicle targeting", "d": ["The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:2000181", "l": "negative regulation of blood vessel morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903980", "l": "positive regulation of microglial cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of microglial cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990355", "l": "L-methionine salvage from methionine sulphoxide", "d": ["The generation of L-methionine from methionine sulphoxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071211", "l": "protein targeting to vacuole involved in autophagy", "d": ["The process of directing proteins towards the vacuole using signals contained within the protein, occurring as part of autophagy, the process in which cells digest parts of their own cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0051145", "l": "smooth muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044592", "l": "response to pullulan", "d": ["A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of pullulan stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902340", "l": "negative regulation of chromosome condensation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090361", "l": "regulation of platelet-derived growth factor production", "d": ["Any process that modulates the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.327400668044291", "identifiers": [{"i": "GO:0002832", "l": "negative regulation of response to biotic stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060382", "l": "regulation of DNA strand elongation", "d": ["Any process that modulates the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003311", "l": "pancreatic D cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046275", "l": "flavonoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of flavonoids, a group of phenolic derivatives containing a flavan skeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0000741", "l": "karyogamy", "d": ["The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902804", "l": "negative regulation of synaptic vesicle transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072105", "l": "ureteric peristalsis", "d": ["A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903238", "l": "positive regulation of leukocyte tethering or rolling", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte tethering or rolling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018021", "l": "peptidyl-histidine methylation", "d": ["The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine) or peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097616", "l": "positive regulation by host of symbiont type IV pilus-dependent motility", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032705", "l": "negative regulation of interleukin-21 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-21 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902219", "l": "negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042396", "l": "phosphagen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.672305786814945", "identifiers": [{"i": "GO:0019915", "l": "lipid storage", "d": ["The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035938", "l": "estradiol secretion", "d": ["The regulated release of estradiol into the circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043963", "l": "modulation by symbiont of host adenylate cyclase-mediated signal transduction", "d": ["Any process in which the symbiont modulates the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036050", "l": "peptidyl-lysine succinylation", "d": ["The modification of a peptidyl-lysine residue by the addition of a succinyl group (CO-CH2-CH2-CO) to form N6-succinyl-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060116", "l": "vestibular receptor cell morphogenesis", "d": ["Any process that alters the size or shape of a vestibular receptor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003368", "l": "cell-matrix adhesion involved in mesendodermal cell migration", "d": ["The binding of a cell to the extracellular matrix that contributes to the directed movement of a mesendodermal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000593", "l": "negative regulation of metanephric DCT cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of metanephric DCT cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903449", "l": "androst-4-ene-3,17-dione biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of androst-4-ene-3,17-dione."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900513", "l": "negative regulation of starch utilization system complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of starch utilization system complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901272", "l": "2-dehydro-3-deoxy-D-gluconic acid metabolic process", "d": ["The chemical reactions and pathways involving 2-dehydro-3-deoxy-D-gluconic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0036100", "l": "leukotriene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010725", "l": "regulation of primitive erythrocyte differentiation", "d": ["Any process that modulates the rate, frequency, or extent of primitive erythrocyte differentiation. Primitive erythrocyte differentiation occurs as part of the process of primitive hemopoiesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901074", "l": "regulation of engulfment of apoptotic cell", "d": ["Any process that modulates the frequency, rate or extent of engulfment of apoptotic cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007541", "l": "sex determination, primary response to X:A ratio", "d": ["The developmental process in which an organism interprets its X to autosomal chromosomal complement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0036180", "l": "filamentous growth of a population of unicellular organisms in response to biotic stimulus", "d": ["The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002047", "l": "phenazine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a phenazine antibiotic, a polycyclic pyrazine with two nitrogen atoms in the ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010947", "l": "negative regulation of meiotic joint molecule formation", "d": ["Any process that decreases the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070651", "l": "nonfunctional rRNA decay", "d": ["An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021715", "l": "inferior olivary nucleus formation", "d": ["The process that gives rise to the inferior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0019326", "l": "nitrotoluene metabolic process", "d": ["The chemical reactions and pathways involving nitrotoluene, any methylbenzene molecule with NO2 group(s) attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901840", "l": "negative regulation of RNA polymerase I regulatory region sequence-specific DNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050949", "l": "negative regulation of late stripe melanocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of late stripe melanocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018213", "l": "peptidyl-valine modification", "d": ["The modification of peptidyl-valine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.009127879491089", "identifiers": [{"i": "GO:0022603", "l": "regulation of anatomical structure morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903282", "l": "regulation of glutathione peroxidase activity", "d": ["Any process that modulates the frequency, rate or extent of glutathione peroxidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046469", "l": "platelet activating factor metabolic process", "d": ["The chemical reactions and pathways involving platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0010984", "l": "regulation of lipoprotein particle clearance", "d": ["Any process that modulates the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060377", "l": "negative regulation of mast cell differentiation", "d": ["Any process that decreases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.356779217613806", "identifiers": [{"i": "GO:0051251", "l": "positive regulation of lymphocyte activation", "d": ["Any process that activates or increases the frequency, rate or extent of lymphocyte activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900738", "l": "positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0016103", "l": "diterpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diterpenoid compounds, terpenoids with four isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019472", "l": "4-hydroxyproline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048625", "l": "myoblast fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001989", "l": "positive regulation of the force of heart contraction involved in baroreceptor response to decreased systemic arterial blood pressure", "d": ["Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as part of the baroreceptor response to decreased blood pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901906", "l": "diadenosine pentaphosphate metabolic process", "d": ["The chemical reactions and pathways involving diadenosine pentaphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018019", "l": "N-terminal peptidyl-glutamine methylation", "d": ["The methylation of a glutamine residue in proteins to form the peptidyl-N5-methyl-L-glutamine derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0042843", "l": "D-xylose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-xylose, a naturally occurring plant polysaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0014833", "l": "skeletal muscle satellite stem cell asymmetric division", "d": ["The asymmetric division of a skeletal muscle satellite stem cell to produce two daughter cells, one of which is destined to differentiate and the other to be a quiescent cell that restocks the satellite cell pool."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0031016", "l": "pancreas development", "d": ["The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.082891735641667", "identifiers": [{"i": "GO:0000819", "l": "sister chromatid segregation", "d": ["The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0006104", "l": "succinyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving succinyl-CoA, a compound composed of the monovalent acyl group 3-carboxypropanoyl, derived from succinic acid by loss of one OH group, linked to coenzyme A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0032890", "l": "regulation of organic acid transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000510", "l": "positive regulation of dendritic cell chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0070166", "l": "enamel mineralization", "d": ["The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901296", "l": "negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018929", "l": "methyl fluoride metabolic process", "d": ["The chemical reactions and pathways involving methyl fluoride, fluorine-substituted methane, a gaseous halogenated hydrocarbon that has been investigated as an inhibitor of methanotrophy and nitrification in soils."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044180", "l": "filamentous growth of a unicellular organism", "d": ["The process in which a unicellular organism grows in a threadlike, filamentous shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990064", "l": "ground tissue pattern formation", "d": ["The regionalization process that gives rise to the patterning of the ground tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042790", "l": "nucleolar large rRNA transcription by RNA polymerase I", "d": ["The synthesis of the large ribosomal RNA (rRNA) transcript which encodes several rRNAs, e.g. in mammals 28S, 18S and 5.8S, from a nuclear DNA template transcribed by RNA polymerase I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035621", "l": "ER to Golgi ceramide transport", "d": ["The directed movement of a ceramide from the endoplasmic reticulum (ER) to the Golgi. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032385", "l": "positive regulation of intracellular cholesterol transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0043114", "l": "regulation of vascular permeability", "d": ["Any process that modulates the extent to which blood vessels can be pervaded by fluid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035622", "l": "intrahepatic bile duct development", "d": ["The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0046379", "l": "extracellular polysaccharide metabolic process", "d": ["The chemical reactions and pathways involving polysaccharides used in extracellular structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0110100", "l": "spindle pole body separation", "d": ["The release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that is severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar spindle to assemble."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990461", "l": "detoxification of iron ion", "d": ["Any process that reduces or removes the toxicity of iron ion. These include transport of iron away from sensitive areas and to compartments or complexes whose purpose is sequestration of iron ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042935", "l": "achromobactin transport", "d": ["The directed movement of achromobactin, a citrate siderophore, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904540", "l": "positive regulation of glycolytic process through fructose-6-phosphate", "d": ["Any process that activates or increases the frequency, rate or extent of glycolytic process through fructose-6-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0010952", "l": "positive regulation of peptidase activity", "d": ["Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030583", "l": "myxococcal fruiting body development", "d": ["The process whose specific outcome is the progression of the myxococcal fruiting body over time, from its formation to the mature structure. The process begins when myxococci respond to a lack of nutrients in the environment and ends when the myxococcal fruiting body is a mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120313", "l": "regulation of oocyte karyosome formation", "d": ["Any process that modulates the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0030654", "l": "beta-lactam antibiotic biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046066", "l": "dGDP metabolic process", "d": ["The chemical reactions and pathways involving dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990091", "l": "sodium-dependent self proteolysis", "d": ["The sodium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051696", "l": "pointed-end actin filament uncapping", "d": ["The removal of capping protein from the pointed (or minus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009440", "l": "cyanate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cyanate, NCO-, the anion of cyanic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141023", "l": "disruption by symbiont of host cell-cell adhesion", "d": ["The process by which a symbiont disupts cell-cell adhesion in its host."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0006541", "l": "glutamine metabolic process", "d": ["The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000103", "l": "positive regulation of mammary stem cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of mammary stem cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.134834654920184", "identifiers": [{"i": "GO:0001818", "l": "negative regulation of cytokine production", "d": ["Any process that stops, prevents, or reduces the rate of production of a cytokine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000818", "l": "negative regulation of myoblast proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015014", "l": "heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polysaccharide chain component of heparan sulfate proteoglycan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905457", "l": "negative regulation of lymphoid progenitor cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000819", "l": "regulation of nucleotide-excision repair", "d": ["Any process that modulates the frequency, rate or extent of nucleotide-excision repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001544", "l": "initiation of primordial ovarian follicle growth", "d": ["Increase in size of primordial follicles including proliferation and shape changes of granulosa and/or theca cells until oocyte is surrounded by one layer of cuboidal shaped granulosa cells (primary follicle)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048933", "l": "afferent axon development in posterior lateral line nerve", "d": ["The process whose specific outcome is the progression of an afferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the posterior lateral line nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043335", "l": "protein unfolding", "d": ["The process of assisting in the disassembly of non-covalent linkages in a protein or protein aggregate, often where the proteins are in a non-functional or denatured state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072013", "l": "glomus development", "d": ["The progression of the glomus over time from its initial formation until its mature state. The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031364", "l": "N-terminal protein amino acid deamination, from side chain", "d": ["The removal of an amino group from the side chain of an N-terminal asparagine or glutamine residue of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046726", "l": "positive regulation by virus of viral protein levels in host cell", "d": ["Any process where the infecting virus increases the levels of viral proteins in a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0018131", "l": "oxazole or thiazole biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.871876592857262", "identifiers": [{"i": "GO:1901659", "l": "glycosyl compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycosyl compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010022", "l": "meristem determinacy", "d": ["The process in which a meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060710", "l": "chorio-allantoic fusion", "d": ["The cell-cell adhesion process in which the cells of the chorion fuse to the cells of the allantois."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007502", "l": "digestive tract mesoderm development", "d": ["The process whose specific outcome is the progression of the digestive tract mesoderm over time, from its formation to the mature structure. The digestive tract mesoderm is portion of the middle layer of the three primary germ layers of the embryo which will go on to form part of the digestive tract of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061567", "l": "dCMP phosphorylation", "d": ["The process of introducing a phosphate group into dCMP, deoxycytidine monophosphate, to produce dCDP. Addition of two phosphate groups produces dCTP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0072525", "l": "pyridine-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.426153789046865", "identifiers": [{"i": "GO:0022403", "l": "cell cycle phase", "d": ["One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060778", "l": "primary leaflet morphogenesis", "d": ["The process in which the primary leaflet attains its shape. A primary leaflet is a leaflet that develops directly from the rachis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904352", "l": "positive regulation of protein catabolic process in the vacuole", "d": ["Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0090316", "l": "positive regulation of intracellular protein transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0044495", "l": "modulation of blood pressure in another organism", "d": ["A process by which one organism modulates the force with which blood travels through the circulatory system of another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075507", "l": "entry of viral genome into host nucleus via docking of viral capsid to the nuclear pore complex and injection of viral genome", "d": ["Viral penetration into the host nucleus where the where a viral capsid docks on the cytoplasmic side of the nuclear pore complex (NPC) and ejects the viral genome through the pore into the nucleoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018029", "l": "peptidyl-lysine palmitoylation", "d": ["The palmitoylation of peptidyl-lysine to form peptidyl-N6-palmitoyl-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0080164", "l": "regulation of nitric oxide metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046290", "l": "isoflavonoid phytoalexin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0072087", "l": "renal vesicle development", "d": ["The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.261443428098588", "identifiers": [{"i": "GO:0048532", "l": "anatomical structure arrangement", "d": ["The process that gives rise to the configuration of the constituent parts of an anatomical structure. This process pertains to the physical shaping of a rudimentary structure. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0048520", "l": "positive regulation of behavior", "d": ["Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0086009", "l": "membrane repolarization", "d": ["The process in which ions are transported across a membrane such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071223", "l": "cellular response to lipoteichoic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061344", "l": "regulation of cell adhesion involved in heart morphogenesis", "d": ["Any process that modulates the extent of cell adhesion contributing to the shaping of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141041", "l": "disruption of extracellular matrix of another organism", "d": ["The chemical reactions and pathways performed by an organism resulting in the breakdown of the extracellular matrix of another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021714", "l": "inferior olivary nucleus morphogenesis", "d": ["The process in which the anatomical structure of the inferior olivary nucleus is generated and organized. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0050768", "l": "negative regulation of neurogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160054", "l": "microfibril assembly", "d": ["The aggregation, arrangement and bonding together of microfibril."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030726", "l": "male germline ring canal formation", "d": ["Formation of the intercellular bridges that connect the germ-line cells of a male cyst."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072757", "l": "cellular response to camptothecin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061610", "l": "glycerol to glycerone phosphate metabolic process", "d": ["The chemical reactions and pathways in which glycerol, 1,2,3-propanetriol, is converted to glycerone phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097698", "l": "telomere maintenance via base-excision repair", "d": ["A telomere maintenance process that occurs by base-excision repair of telomeric DNA in response to DNA damage. Telomeric sequences are particularly susceptible to oxidative DNA damage, due to their G-rich nature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060283", "l": "negative regulation of oocyte development", "d": ["Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:2001243", "l": "negative regulation of intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030200", "l": "heparan sulfate proteoglycan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4) linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902179", "l": "verruculogen metabolic process", "d": ["The chemical reactions and pathways involving verruculogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075223", "l": "regulation of sporangium germination", "d": ["Any process that modulates the frequency, rate or extent of sporangium germination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001178", "l": "positive regulation of mediator complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of mediator complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060891", "l": "limb granular cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal granular cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905014", "l": "positive regulation of 'de novo' NAD biosynthetic process from tryptophan", "d": ["Any process that activates or increases the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0033077", "l": "T cell differentiation in thymus", "d": ["The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061969", "l": "maintenance of left sidedness", "d": ["The organization process that preserves the left sidedness in an organism's body plan or part of an organism with respect to the left and right halves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051514", "l": "negative regulation of monopolar cell growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010077", "l": "maintenance of inflorescence meristem identity", "d": ["The process in which an organism retains a population of inflorescence meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035680", "l": "posterior lateral line neuromast hair cell morphogenesis", "d": ["The change in form (cell shape and size) that occurs when a posterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098795", "l": "global gene silencing by mRNA cleavage", "d": ["A posttranscriptional gene silencing pathway that involves the cleavage of mRNAs in a non-gene-specific manner."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990019", "l": "protein storage vacuole organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a protein storage vacuole, a storage vacuole that contains a lytic vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0045064", "l": "T-helper 2 cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires specialized features of a T-helper 2 (Th2) cell. A Th2 cell is a CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000993", "l": "positive regulation of galactomannan catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of galactomannan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.618854952666041", "identifiers": [{"i": "GO:0045058", "l": "T cell selection", "d": ["The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090437", "l": "socket cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a socket cell, a shoot epidermal cell that surrounds a trichome and provides its support."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901202", "l": "negative regulation of extracellular matrix assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.295828638494967", "identifiers": [{"i": "GO:0006821", "l": "chloride transport", "d": ["The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904403", "l": "cellular response to nocodazole", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002877", "l": "regulation of acute inflammatory response to non-antigenic stimulus", "d": ["Any process that modulates the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:0034204", "l": "lipid translocation", "d": ["The translocation, or flipping, of lipid molecules from one monolayer of a membrane bilayer to the opposite monolayer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.442476542024195", "identifiers": [{"i": "GO:0050890", "l": "cognition", "d": ["The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141034", "l": "perturbation by symbiont of host actin cytoskeleton via inhibition of actin polymerization", "d": ["The process in which an organism effects a change that disrupts the host actin cytoskeleton by inhibiting host actin from polymerizing. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0006273", "l": "lagging strand elongation", "d": ["The process in which an existing DNA strand is extended in a net 3' to 5' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002459", "l": "adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains", "d": ["An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001282", "l": "negative regulation of muscle cell chemotaxis toward tendon cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a muscle cell towards a tendon cell in response to an external stimulus. For example, when the muscle cell arrives at the target tendon cell, migration is arrested so that attachments can be made between the cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071990", "l": "maintenance of protein location to spindle pole body", "d": ["Any process in which a protein is maintained in a specific location at the spindle pole body, and is prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030727", "l": "germarium-derived female germ-line cyst formation", "d": ["Formation, in a germarium, of a group of interconnected cells derived from a single female gonial founder cell (a cystoblast). The germarium is the most anterior portion of an insect ovariole. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900058", "l": "regulation of sulfate assimilation", "d": ["Any process that modulates the frequency, rate or extent of sulfate assimilation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905515", "l": "non-motile cilium assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009137", "l": "purine nucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032694", "l": "negative regulation of interleukin-11 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-11 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900933", "l": "negative regulation of nonadec-1-ene metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903601", "l": "thermospermine metabolic process", "d": ["The chemical reactions and pathways involving thermospermine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903283", "l": "negative regulation of glutathione peroxidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glutathione peroxidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0090276", "l": "regulation of peptide hormone secretion", "d": ["Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "50.636682489717096", "identifiers": [{"i": "GO:0022402", "l": "cell cycle process", "d": ["The cellular process that ensures successive accurate and complete genome replication and chromosome segregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021736", "l": "globose nucleus development", "d": ["The process whose specific outcome is the progression of the globose nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019929", "l": "peptide cross-linking via 4-(S-L-cysteinyl)-L-glutamic acid", "d": ["The cross-linking of a cysteine residue to a glutamic acid residue to form 4-(S-L-cysteinyl)-L-glutamic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904225", "l": "positive regulation of glucuronosyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of glucuronosyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0010769", "l": "regulation of cell morphogenesis involved in differentiation", "d": ["Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060484", "l": "lung-associated mesenchyme development", "d": ["The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048757", "l": "pigment granule maturation", "d": ["Steps required to form a membrane-bounded organelle into a pigment granule containing pigment. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061865", "l": "polarized secretion of basement membrane proteins in epithelium", "d": ["The basement membrane constituent secretion in which there is a restriction or targeting of basement membrane proteins for controlled release on the basal side of polarized epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046186", "l": "acetaldehyde biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903930", "l": "regulation of pyrimidine-containing compound salvage", "d": ["Any process that modulates the frequency, rate or extent of pyrimidine-containing compound salvage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0062042", "l": "regulation of cardiac epithelial to mesenchymal transition", "d": ["Any process that modulates the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903193", "l": "sesquarterpene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sesquarterpene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0062086", "l": "regulation of vein smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of vein smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0001119", "l": "protein-DNA-RNA complex remodeling", "d": ["The acquisition, loss, or modification of macromolecules within a protein-DNA-RNA complex, resulting in the alteration of an existing complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045769", "l": "negative regulation of asymmetric cell division", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070861", "l": "regulation of protein exit from endoplasmic reticulum", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902243", "l": "copal-8-ol diphosphate(3-) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of copal-8-ol diphosphate(3-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0017156", "l": "calcium-ion regulated exocytosis", "d": ["The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017197", "l": "N-terminal peptidyl-proline acetylation", "d": ["The acetylation of the N-terminal proline of proteins to form the derivative N-acetyl-L-proline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904995", "l": "negative regulation of leukocyte adhesion to vascular endothelial cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043654", "l": "recognition of apoptotic cell", "d": ["The process in which a cell interprets signals (in the form of specific proteins and lipids) on the surface of a dying cell which it will engulf and remove by phagocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000807", "l": "regulation of synaptic vesicle clustering", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle clustering."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001815", "l": "positive regulation of antibody-dependent cellular cytotoxicity", "d": ["Any process that activates or increases the frequency, rate or extent of antibody-dependent cellular cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042450", "l": "arginine biosynthetic process via ornithine", "d": ["The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010780", "l": "meiotic DNA double-strand break formation involved in reciprocal meiotic recombination", "d": ["The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0007039", "l": "protein catabolic process in the vacuole", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0045777", "l": "positive regulation of blood pressure", "d": ["Any process in which the force of blood traveling through the circulatory system is increased."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905238", "l": "cellular response to cyclosporin A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010933", "l": "positive regulation of macrophage tolerance induction", "d": ["Any process that increases the frequency, rate, or extent of B cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0072074", "l": "kidney mesenchyme development", "d": ["The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990227", "l": "paranodal junction maintenance", "d": ["The maintenance of a paranodal junction, a highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. A paranodal junction flanks the node of Ranvier in myelinated nerve, electrically isolates the myelinated from unmyelinated nerve segments, and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000735", "l": "positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation", "d": ["Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010074", "l": "maintenance of meristem identity", "d": ["The process in which an organism retains a population of meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0032055", "l": "negative regulation of translation in response to stress", "d": ["Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035293", "l": "chitin-based larval cuticle pattern formation", "d": ["The process that gives rise to the patterns of cell differentiation in the chitin-based larval cuticle. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0110004", "l": "positive regulation of tRNA methylation", "d": ["Any process that activates or increases the frequency, rate or extent of tRNA methylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070202", "l": "regulation of establishment of protein localization to chromosome", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1904601", "l": "protein transport to mating projection actin fusion focus", "d": ["A process in which a protein is transported to a location within an actin fusion focus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0051964", "l": "negative regulation of synapse assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0018991", "l": "egg-laying behavior", "d": ["A reproductive behavior that results in the deposition of eggs (either fertilized or not) upon a surface or into a medium such as water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080157", "l": "regulation of plant-type cell wall organization or biogenesis", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving plant-type cell wall organization or biogenesis. Plant-type cell wall organization or biogenesis is a process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046175", "l": "aldonic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903848", "l": "negative regulation of aorta morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:1902645", "l": "tertiary alcohol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tertiary alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070962", "l": "positive regulation of neutrophil mediated killing of bacterium", "d": ["Any process that increases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045778", "l": "positive regulation of ossification", "d": ["Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903769", "l": "negative regulation of cell proliferation in bone marrow", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in bone marrow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019493", "l": "arginine catabolic process to proline", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0043316", "l": "cytotoxic T cell degranulation", "d": ["The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905291", "l": "positive regulation of CAMKK-AMPK signaling cascade", "d": ["Any process that activates or increases the frequency, rate or extent of CAMKK-AMPK signaling cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071989", "l": "establishment of protein localization to spindle pole body", "d": ["The directed movement of a protein to a specific location at the spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.879406879579491", "identifiers": [{"i": "GO:0009069", "l": "serine family amino acid metabolic process", "d": ["The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905278", "l": "positive regulation of epithelial tube formation", "d": ["Any process that activates or increases the frequency, rate or extent of epithelial tube formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048456", "l": "stamen structural organization", "d": ["The process that contributes to the act of creating the structural organization of the stamen. This process pertains to the physical shaping of a rudimentary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061094", "l": "regulation of turning behavior involved in mating", "d": ["Any process that modulates the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001105", "l": "maltoheptaose transport", "d": ["The directed movement of a maltoheptaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000183", "l": "negative regulation of progesterone biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of progesterone biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.807308174533304", "identifiers": [{"i": "GO:0009611", "l": "response to wounding", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0018973", "l": "trinitrotoluene metabolic process", "d": ["The chemical reactions and pathways involving trinitrotoluene, a methylated benzene molecule with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0010160", "l": "formation of animal organ boundary", "d": ["The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0006995", "l": "cellular response to nitrogen starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0090085", "l": "regulation of protein deubiquitination", "d": ["Any process that modulates the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0009292", "l": "horizontal gene transfer", "d": ["The introduction of genetic information into a cell to create a genetically different individual, without production of new individuals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:2001026", "l": "regulation of endothelial cell chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072444", "l": "response to mitotic DNA replication checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of mitotic DNA replication checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.381173084437549", "identifiers": [{"i": "GO:0015718", "l": "monocarboxylic acid transport", "d": ["The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0180018", "l": "cytoplasmic polyadenylation-dependent RNA catabolic process", "d": ["The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0045575", "l": "basophil activation", "d": ["The change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061197", "l": "fungiform papilla morphogenesis", "d": ["The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "37.009961361876016", "identifiers": [{"i": "GO:0035239", "l": "tube morphogenesis", "d": ["The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048399", "l": "regulation of intermediate mesodermal cell fate specification", "d": ["Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000138", "l": "positive regulation of cell proliferation involved in heart morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903748", "l": "negative regulation of establishment of protein localization to mitochondrion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006187", "l": "dGTP biosynthetic process from dGDP", "d": ["The chemical reactions and pathways resulting in the formation of dGTP, deoxyguanosine triphosphate (2'-deoxyguanosine 5'-triphosphate) from other compounds, including gGDP, deoxyguanosine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0071600", "l": "otic vesicle morphogenesis", "d": ["The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904126", "l": "convergent extension involved in notochord morphogenesis", "d": ["Any convergent extension that is involved in notochord morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.669997983625713", "identifiers": [{"i": "GO:0006310", "l": "DNA recombination", "d": ["Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075268", "l": "regulation of aecium development", "d": ["Any process that modulates the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903926", "l": "cellular response to bisphenol A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.258924354957735", "identifiers": [{"i": "GO:0019724", "l": "B cell mediated immunity", "d": ["Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0007044", "l": "cell-substrate junction assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0007030", "l": "Golgi organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010151", "l": "chloroplast elongation", "d": ["Expansion of the chloroplast that usually precedes division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901933", "l": "bicyclogermacrene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of bicyclogermacrene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043321", "l": "regulation of natural killer cell degranulation", "d": ["Any process that modulates the frequency, rate, or extent of natural killer cell degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0010657", "l": "muscle cell apoptotic process", "d": ["A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003290", "l": "atrial septum secundum morphogenesis", "d": ["The process in which anatomical structure of an atrial septum secundum is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061720", "l": "6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde", "d": ["The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfolactaldehyde (SLA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080086", "l": "stamen filament development", "d": ["The process whose specific outcome is the progression of the filament over time, from its formation to the mature structure. Filament is the stalk of a stamen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042342", "l": "cyanogenic glycoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031293", "l": "membrane protein intracellular domain proteolysis", "d": ["The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0043038", "l": "amino acid activation", "d": ["The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051770", "l": "positive regulation of nitric-oxide synthase biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0043267", "l": "negative regulation of potassium ion transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014868", "l": "cross bridge cycling involved in regulation of the velocity of shortening in skeletal muscle contraction", "d": ["A process in which cross bridges are broken and reformed during filament sliding as part of the regulation of the velocity of shortening in skeletal muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0018105", "l": "peptidyl-serine phosphorylation", "d": ["The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090308", "l": "regulation of DNA methylation-dependent heterochromatin formation", "d": ["Any process that modulates the rate, frequency, or extent of DNA methylation-dependent heterochromatin formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043710", "l": "cell adhesion involved in multi-species biofilm formation", "d": ["The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm composed of microorganisms of different species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060544", "l": "regulation of necroptotic process", "d": ["Any process that modulates the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070108", "l": "negative regulation of interleukin-27-mediated signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of an interleukin-27-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904482", "l": "cellular response to tetrahydrofolate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044725", "l": "epigenetic programming in the zygotic pronuclei", "d": ["The global programming of epigenetic modifications in the zygote following fertilization. The paternal genome undergoes active DNA demethylation before the first cell division, while the adjacent maternal genome is protected from this process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900971", "l": "regulation of sarcinapterin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of sarcinapterin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000640", "l": "positive regulation of SREBP signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905610", "l": "regulation of mRNA cap binding", "d": ["Any process that modulates the frequency, rate or extent of mRNA cap binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003020", "l": "detection of reduced oxygen by chemoreceptor signaling", "d": ["The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901979", "l": "regulation of inward rectifier potassium channel activity", "d": ["Any process that modulates the frequency, rate or extent of inward rectifier potassium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.287337192553075", "identifiers": [{"i": "GO:0048584", "l": "positive regulation of response to stimulus", "d": ["Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0001993", "l": "regulation of systemic arterial blood pressure by norepinephrine-epinephrine", "d": ["The process in which the secretion of norepinephrine or epinephrine into the bloodstream modulates the force with which blood passes through the circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051366", "l": "protein decanoylation", "d": ["The modification of a protein amino acid by formation of an ester or amide with decanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071579", "l": "regulation of zinc ion transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000150", "l": "regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018313", "l": "peptide cross-linking via L-alanyl-5-imidazolinone glycine", "d": ["The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, an alanine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901923", "l": "negative regulation of sclerotium development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sclerotium development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106165", "l": "negative regulation of exonucleolytic catabolism of deadenylated mRNA", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072263", "l": "metanephric intraglomerular mesangial cell proliferation", "d": ["The multiplication or reproduction of intraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048084", "l": "positive regulation of adult chitin-containing cuticle pigmentation", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007375", "l": "anterior midgut invagination", "d": ["Internalization of the anterior midgut into the interior of the embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015938", "l": "coenzyme A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006798", "l": "polyphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a polyphosphate, the anion or salt of polyphosphoric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019732", "l": "antifungal humoral response", "d": ["An immune response against a fungus mediated through a body fluid. An example of this process is the antifungal humoral response in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098923", "l": "retrograde trans-synaptic signaling by soluble gas", "d": ["Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an soluble gas ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071455", "l": "cellular response to hyperoxia", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090410", "l": "malonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of malonate, the propanedioate ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045217", "l": "cell-cell junction maintenance", "d": ["The maintenance of junctions between cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903058", "l": "positive regulation of melanosome organization", "d": ["Any process that activates or increases the frequency, rate or extent of melanosome organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0009639", "l": "response to red or far red light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990603", "l": "dark adaptation", "d": ["The process by which the rods of the retina gradually become fully responsive to dim light when no longer exposed to bright light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0050924", "l": "positive regulation of negative chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901168", "l": "3-chlorocatechol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-chlorocatechol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990548", "l": "mitochondrial FAD transmembrane transport", "d": ["The process in which FAD is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071171", "l": "site-specific DNA replication termination at RTS1 barrier", "d": ["A DNA replication termination process that takes place at the RTS1 termination site in the mating type locus, in a specific direction required for subsequent imprinting and mating-type switching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900494", "l": "regulation of butyryl-CoA biosynthetic process from acetyl-CoA", "d": ["Any process that modulates the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0020035", "l": "adhesion of symbiont to microvasculature", "d": ["The adherence of symbiont-infected erythrocytes to microvascular endothelium via symbiont proteins embedded in the membrane of the erythrocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035646", "l": "endosome to melanosome transport", "d": ["The directed movement of substances from endosomes to the melanosome, a specialised lysosome-related organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019635", "l": "2-aminoethylphosphonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-aminoethylphosphonate, also known as ciliatine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031953", "l": "negative regulation of protein autophosphorylation", "d": ["Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0010923", "l": "negative regulation of phosphatase activity", "d": ["Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000398", "l": "regulation of thymocyte aggregation", "d": ["Any process that modulates the frequency, rate or extent of thymocyte aggregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018240", "l": "protein S-linked glycosylation via cysteine", "d": ["The glycosylation of protein via the sulfur atom of peptidyl-cysteine, forming S-glycosyl-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046476", "l": "glycosylceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061764", "l": "late endosome to lysosome transport via multivesicular body sorting pathway", "d": ["The directed movement of substances from late endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0007398", "l": "ectoderm development", "d": ["The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000354", "l": "regulation of ovarian follicle development", "d": ["Any process that modulates the frequency, rate or extent of ovarian follicle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901594", "l": "response to capsazepine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019574", "l": "sucrose catabolic process via 3'-ketosucrose", "d": ["The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds via the conversion of sucrose to 3'-ketosucrose. 3'-ketosucrose is hydrolyzed to 3-ketoglucose and fructose, and the 3-ketoglucose is then be converted to glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0009658", "l": "chloroplast organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000331", "l": "regulation of terminal button organization", "d": ["Any process that modulates the frequency, rate or extent of terminal button organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060679", "l": "trifid subdivision of terminal units involved in ureteric bud branching", "d": ["The process in which a ureteric bud splits into three units at its end."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903132", "l": "regulation of tube lumen cavitation", "d": ["Any process that modulates the frequency, rate or extent of tube lumen cavitation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006244", "l": "pyrimidine nucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0072110", "l": "glomerular mesangial cell proliferation", "d": ["The multiplication or reproduction of glomerular mesangial cells, resulting in the expansion of the population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140471", "l": "positive regulation of transepithelial migration of symbiont in host", "d": ["Any process that activates or increases the frequency, rate or extent of transepithelial migration of symbiont in host."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900553", "l": "asperfuranone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of asperfuranone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903477", "l": "mitotic contractile ring actin filament bundle assembly", "d": ["Any actin filament bundle assembly that is involved in mitotic actomyosin contractile ring assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021563", "l": "glossopharyngeal nerve development", "d": ["Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071395", "l": "cellular response to jasmonic acid stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0002583", "l": "regulation of antigen processing and presentation of peptide antigen", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048615", "l": "embryonic anterior midgut (ectodermal) morphogenesis", "d": ["The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the embryonic phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904392", "l": "cellular response to ciliary neurotrophic factor", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0018076", "l": "N-terminal peptidyl-lysine acetylation", "d": ["The acetylation of the N-terminal lysine of proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0046131", "l": "pyrimidine ribonucleoside metabolic process", "d": ["The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902060", "l": "positive regulation of sporocarp development involved in sexual reproduction", "d": ["Any process that activates or increases the frequency, rate or extent of sporocarp development involved in sexual reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903669", "l": "positive regulation of chemorepellent activity", "d": ["Any process that activates or increases the frequency, rate or extent of chemorepellent activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042184", "l": "xylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014053", "l": "negative regulation of gamma-aminobutyric acid secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061087", "l": "positive regulation of histone H3-K27 methylation", "d": ["Any process that increases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0051963", "l": "regulation of synapse assembly", "d": ["Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905563", "l": "negative regulation of vascular endothelial cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090384", "l": "phagosome-lysosome docking", "d": ["The initial attachment of a phagosome membrane to a lysosome membrane. Docking requires only that the proteins come close enough to interact and adhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "37.185243588938022", "identifiers": [{"i": "GO:0016331", "l": "morphogenesis of embryonic epithelium", "d": ["The process in which the anatomical structures of embryonic epithelia are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0044843", "l": "cell cycle G1/S phase transition", "d": ["The cell cycle process by which a cell in G1 phase commits to S phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0019694", "l": "alkanesulfonate metabolic process", "d": ["The chemical reactions and pathways involving alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035074", "l": "pupation", "d": ["The act of becoming a pupa, a resting stage in the life cycle of organisms with complete metamorphosis. This event marks the end of the prepupal period and the beginning of the pupal period."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0009649", "l": "entrainment of circadian clock", "d": ["The synchronization of a circadian rhythm to environmental time cues such as light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010930", "l": "negative regulation of auxin mediated signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033075", "l": "isoquinoline alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0071993", "l": "phytochelatin transport", "d": ["The directed movement of a phytochelatin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0120305", "l": "regulation of pigmentation", "d": ["Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0035268", "l": "protein mannosylation", "d": ["The addition of a mannose residue to a protein acceptor molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045975", "l": "positive regulation of translation, ncRNA-mediated", "d": ["Any process, mediated by small non-coding RNAs, that activates or increases the rate that mRNAs are effectively translated into protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:0097530", "l": "granulocyte migration", "d": ["The movement of a granulocyte within or between different tissues and organs of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000126", "l": "negative regulation of octopamine or tyramine signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine or tyramine signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901069", "l": "guanosine-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of guanosine-containing compounds (guanosines)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0061536", "l": "glycine secretion", "d": ["The controlled release of glycine by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046792", "l": "suppression by virus of host cell cycle arrest", "d": ["Viral interference in host cell processes that lead cell cycle arrest, allowing cell division to occur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097296", "l": "activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway", "d": ["Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990863", "l": "acinar cell proliferation", "d": ["The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071404", "l": "cellular response to low-density lipoprotein particle stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035874", "l": "cellular response to copper ion starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of copper ions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903304", "l": "positive regulation of pyruvate kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of pyruvate kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900023", "l": "positive regulation of D-erythro-sphingosine kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of D-erythro-sphingosine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0000912", "l": "assembly of actomyosin apparatus involved in cytokinesis", "d": ["The assembly and arrangement of an apparatus composed of actin, myosin, and associated proteins that will function in cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035345", "l": "regulation of hypoxanthine transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.651613913496419", "identifiers": [{"i": "GO:0099173", "l": "postsynapse organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:1903083", "l": "protein localization to condensed chromosome", "d": ["A process in which a protein is transported to, or maintained in, a location within a condensed chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0008589", "l": "regulation of smoothened signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of smoothened signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0052024", "l": "positive regulation by symbiont of hormone or growth regulator levels in host", "d": ["The increase by an organism of the levels of hormones or growth regulators in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903257", "l": "selenoneine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of selenoneine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0006749", "l": "glutathione metabolic process", "d": ["The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045451", "l": "pole plasm oskar mRNA localization", "d": ["Any process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.082891735641667", "identifiers": [{"i": "GO:0044703", "l": "multi-organism reproductive process", "d": ["A biological process that directly contributes to the process of producing new individuals, involving another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090294", "l": "nitrogen catabolite activation of transcription", "d": ["A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019314", "l": "D-allose metabolic process", "d": ["The chemical reactions and pathways involving D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072259", "l": "metanephric interstitial fibroblast development", "d": ["The process whose specific outcome is the progression of a metanephric interstitial fibroblast over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0052111", "l": "modification by symbiont of host structure", "d": ["The process in which an organism effects a change in an anatomical part or cellular component of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000539", "l": "regulation of protein geranylgeranylation", "d": ["Any process that modulates the frequency, rate or extent of protein geranylgeranylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006771", "l": "riboflavin metabolic process", "d": ["The chemical reactions and pathways involving riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.261443428098588", "identifiers": [{"i": "GO:0048645", "l": "animal organ formation", "d": ["The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903703", "l": "enterocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an enterocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042875", "l": "D-galactonate transmembrane transport", "d": ["The process in which D-galactonate, the D-enantiomer of galactonate, is transported across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0052779", "l": "amino disaccharide metabolic process", "d": ["The chemical reactions and pathways involving any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.967242924124768", "identifiers": [{"i": "GO:0001568", "l": "blood vessel development", "d": ["The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002329", "l": "pre-B cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000563", "l": "positive regulation of CD4-positive, alpha-beta T cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055091", "l": "phospholipid homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990486", "l": "anaerobic fatty acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a fatty acid in the absence of oxygen. A fatty acid is any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043012", "l": "regulation of fusion of sperm to egg plasma membrane", "d": ["Any process that modulates the binding and fusion of a sperm to the oocyte plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018389", "l": "N-terminal peptidyl-valine deamination", "d": ["The deamination of the N-terminal valine residue of a protein to form isobutyrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0006206", "l": "pyrimidine nucleobase metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034378", "l": "chylomicron assembly", "d": ["The non-covalent aggregation and arrangement of proteins and lipids in the intestine to form a chylomicron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902925", "l": "poly(hydroxyalkanoate) biosynthetic process from fatty acid", "d": ["The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from fatty acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046215", "l": "siderophore catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.781964347917338", "identifiers": [{"i": "GO:0061326", "l": "renal tubule development", "d": ["The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904472", "l": "positive regulation of endothelin production", "d": ["Any process that activates or increases the frequency, rate or extent of endothelin production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051292", "l": "nuclear pore complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a nuclear pore complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0048640", "l": "negative regulation of developmental growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032573", "l": "response to phylloquinone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021790", "l": "chemorepulsion of branchiomotor neuron axon in branchial arch mesenchyme", "d": ["The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010441", "l": "guard cell development", "d": ["The process whose specific outcome is the progression of the guard cell over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035358", "l": "regulation of peroxisome proliferator activated receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051850", "l": "acquisition of nutrients from symbiont", "d": ["The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042664", "l": "negative regulation of endodermal cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from specifying into an endoderm cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006035", "l": "cuticle chitin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071608", "l": "macrophage inflammatory protein-1 alpha production", "d": ["The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904899", "l": "positive regulation of hepatic stellate cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of hepatic stellate cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000016", "l": "negative regulation of determination of dorsal identity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of determination of dorsal identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042429", "l": "serotonin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1990504", "l": "dense core granule exocytosis", "d": ["The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense core granule by fusion of the granule with the plasma membrane of a cell in response to increased cytosolic calcium levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1903727", "l": "positive regulation of phospholipid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of phospholipid metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "40.922875402013759", "identifiers": [{"i": "GO:0051716", "l": "cellular response to stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0009730", "l": "detection of carbohydrate stimulus", "d": ["The series of events in which a carbohydrate stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070154", "l": "mitochondrial lysyl-tRNA aminoacylation", "d": ["The process of coupling lysine to lysyl-tRNA in a mitochondrion, catalyzed by lysyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:1903319", "l": "positive regulation of protein maturation", "d": ["Any process that activates or increases the frequency, rate or extent of protein maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010971", "l": "positive regulation of G2/M transition of mitotic cell cycle", "d": ["Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043055", "l": "maintenance of dauer", "d": ["Maintenance of a nematode during the facultative diapause of the dauer (enduring) larval stage of nematode development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060243", "l": "negative regulation of cell growth involved in contact inhibition", "d": ["The negative regulation of cell growth in response to increased cell density."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032831", "l": "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0051596", "l": "methylglyoxal catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018138", "l": "peptide cross-linking via L-serine thiazolecarboxylic acid", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031442", "l": "positive regulation of mRNA 3'-end processing", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0140278", "l": "mitotic division septum assembly", "d": ["The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following mitotic cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006145", "l": "purine nucleobase catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0034644", "l": "cellular response to UV", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031017", "l": "exocrine pancreas development", "d": ["The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072315", "l": "metanephric glomerular epithelial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061340", "l": "establishment or maintenance of monopolar cell polarity regulating cell shape", "d": ["Any cellular process that results in the specification, formation or maintenance of a monopolar intracellular organization or cell growth patterns that regulate the shape of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015863", "l": "xanthosine transport", "d": ["The directed movement of xanthosine, xanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033603", "l": "positive regulation of dopamine secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045963", "l": "negative regulation of dopamine metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018907", "l": "dimethyl sulfoxide metabolic process", "d": ["The chemical reactions and pathways involving dimethyl sulfoxide, DMSO (C2H6OS), an alkyl sulfoxide that is practically odorless in its purified form. As a highly polar organic liquid, it is a powerful solvent. Its biological activities include the ability to penetrate plant and animal tissues and to preserve living cells during freezing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042549", "l": "photosystem II stabilization", "d": ["The stabilization of the photosystem II protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0033206", "l": "meiotic cytokinesis", "d": ["A cell cycle process that results in the division of the cytoplasm of a cell after meiosis, resulting in the separation of the original cell into two daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048054", "l": "R2/R5 cell differentiation", "d": ["The process in which relatively unspecialized cells acquire the specialized features of R2 and R5 photoreceptors. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0007349", "l": "cellularization", "d": ["The separation of a multi-nucleate cell or syncytium into individual cells. An example of this is found in Drosophila melanogaster embryo development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043032", "l": "positive regulation of macrophage activation", "d": ["Any process that stimulates, induces or increases the rate of macrophage activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062032", "l": "cichorine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cichorine, a secondary metabolite found in some species of fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032804", "l": "negative regulation of low-density lipoprotein particle receptor catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905572", "l": "ganglioside GM1 transport to membrane", "d": ["The directed movement of ganglioside GM1 to membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0019350", "l": "teichoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0002778", "l": "antibacterial peptide production", "d": ["The synthesis or release of an antibacterial peptide during an immune response, resulting in an increase in intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072211", "l": "metanephric pyramids development", "d": ["The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071868", "l": "cellular response to monoamine stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003180", "l": "aortic valve morphogenesis", "d": ["The process in which the structure of the aortic valve is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060088", "l": "auditory receptor cell stereocilium organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.807308174533304", "identifiers": [{"i": "GO:0051640", "l": "organelle localization", "d": ["Any process in which an organelle is transported to, and/or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097036", "l": "regulation of plasma membrane sterol distribution", "d": ["Any process that modulates the proportions or spatial arrangement of sterols in the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018280", "l": "protein S-linked glycosylation", "d": ["A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a sulfur atom of a peptidyl-amino-acid such as cysteine or methionine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035027", "l": "leading edge cell fate commitment", "d": ["The commitment of cells to leading edge cell fate and their capacity to differentiate into leading edge cells. Leading edge cells are found at the front of a migrating epithelial sheet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019415", "l": "acetate biosynthetic process from carbon monoxide", "d": ["The chemical reactions and pathways resulting in the formation of acetate from other compounds, including carbon monoxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900923", "l": "regulation of glycine import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of glycine import into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0021683", "l": "cerebellar granular layer morphogenesis", "d": ["The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.379321704503681", "identifiers": [{"i": "GO:0141060", "l": "disruption of anatomical structure in another organism", "d": ["The disruption of the an anatomical structure of another organism, leading to damage or temporary subversion of that structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002357", "l": "defense response to tumor cell", "d": ["Reactions triggered in response to the presence of a tumor cell that act to protect the cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060472", "l": "positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration", "d": ["Any process that activates or increases the frequency, rate or extent of cortical granule exocytosis by directing movement of calcium ions (Ca2+) into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045487", "l": "gibberellin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060591", "l": "chondroblast differentiation", "d": ["The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060061", "l": "Spemann organizer formation", "d": ["Formation of the specialized region on the dorsalmost side of the embryo that acts as the main signaling center establishing the vertebrate body plan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0000289", "l": "nuclear-transcribed mRNA poly(A) tail shortening", "d": ["Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904780", "l": "negative regulation of protein localization to centrosome", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to centrosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000709", "l": "meiotic joint molecule formation", "d": ["The conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. These joint molecules contain Holliday junctions on either side of heteroduplex DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000752", "l": "regulation of glucosylceramide catabolic process", "d": ["Any process that modulates the frequency, rate or extent of glucosylceramide catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160019", "l": "negative regulation of platelet rolling", "d": ["Any process that decreases the rate, frequency, or extent of platelet rolling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0006716", "l": "juvenile hormone metabolic process", "d": ["The chemical reactions and pathways involving juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0014009", "l": "glial cell proliferation", "d": ["The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.403899653192809", "identifiers": [{"i": "GO:0051276", "l": "chromosome organization", "d": ["A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018182", "l": "protein-heme linkage via 3'-L-histidine", "d": ["The covalent linkage of heme and a protein via 3'-L-histidine (otherwise known as pi-heme-histidine, pros-heme-histidine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0090151", "l": "establishment of protein localization to mitochondrial membrane", "d": ["The directed movement of a protein to a specific location in the mitochondrial membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990580", "l": "regulation of cytoplasmic translational termination", "d": ["Any process that modulates the frequency, rate or extent of cytoplasmic translational termination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990549", "l": "mitochondrial NAD transmembrane transport", "d": ["The process in which NAD is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032629", "l": "interleukin-25 production", "d": ["The appearance of interleukin-25 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071299", "l": "cellular response to vitamin A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905803", "l": "negative regulation of cellular response to manganese ion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to manganese ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036159", "l": "inner dynein arm assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0036388", "l": "pre-replicative complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the pre-replicative complex, a protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030645", "l": "glucose catabolic process to butyrate", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glucose, with the production of acetic acid, butyric acid, carbon dioxide (CO2), and dihydrogen; effected by some saccharolytic species of Clostridium, e.g. C. butyricum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0033687", "l": "osteoblast proliferation", "d": ["The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035896", "l": "positive regulation of mast cell degranulation in another organism", "d": ["Any process in which an organism increases the frequency, rate or extent of blood mast cell degranulation in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1990776", "l": "response to angiotensin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904107", "l": "protein localization to microvillus membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within a microvillus membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110022", "l": "regulation of cardiac muscle myoblast proliferation", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090532", "l": "L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate", "d": ["The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate UDP-alpha-D-glucuronate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018070", "l": "peptidyl-serine phosphopantetheinylation", "d": ["The phosphopantetheinylation of peptidyl-serine to form peptidyl-O-phosphopantetheine-L-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060643", "l": "epithelial cell differentiation involved in mammary gland bud morphogenesis", "d": ["The process in which a cell of the mammary placode becomes a cell of the mammary gland bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0086067", "l": "AV node cell to bundle of His cell communication", "d": ["The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035018", "l": "adult chitin-based cuticle pattern formation", "d": ["The process that gives rise to the patterns of cell differentiation that will arise in the chitin-based adult cuticle. An example of this process is adult chitin-based cuticle pattern formation in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045224", "l": "positive regulation of CD4 production", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031496", "l": "positive regulation of mating type switching", "d": ["Any process that activates or increases the frequency, rate or extent of mating type switching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010524", "l": "positive regulation of calcium ion transport into cytosol", "d": ["Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048713", "l": "regulation of oligodendrocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071318", "l": "cellular response to ATP", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051542", "l": "elastin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of elastin, a fibrous glycoprotein found in elastic tissues such as the walls of arteries."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904507", "l": "positive regulation of telomere maintenance in response to DNA damage", "d": ["Any process that activates or increases the frequency, rate or extent of telomere maintenance in response to DNA damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903549", "l": "positive regulation of growth hormone activity", "d": ["Any process that activates or increases the frequency, rate or extent of growth hormone activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032596", "l": "protein transport into membrane raft", "d": ["The directed movement of a protein into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046518", "l": "octamethylcyclotetrasiloxane metabolic process", "d": ["The chemical reactions and pathways involving octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032224", "l": "positive regulation of synaptic transmission, cholinergic", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001265", "l": "positive regulation of C-C chemokine binding", "d": ["Any process that activates or increases the frequency, rate or extent of C-C chemokine binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021592", "l": "fourth ventricle development", "d": ["The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000753", "l": "positive regulation of glucosylceramide catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of glucosylceramide catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010364", "l": "regulation of ethylene biosynthetic process", "d": ["Any process that modulates the frequency, rate, or extent of an ethylene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0016121", "l": "carotene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carotenes, hydrocarbon carotenoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090106", "l": "pancreatic E cell fate commitment", "d": ["The commitment of a cell to a pancreatic E cell fate and its capacity to differentiate into a pancreatic E cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010783", "l": "proboscis morphogenesis, eye-antennal disc-derived", "d": ["The process in which the anatomical structures of the proboscis that are derived from the eye-antennal disc are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046074", "l": "dTMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dTMP, deoxyribosylthymine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905439", "l": "response to chondroitin 6'-sulfate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051725", "l": "protein de-ADP-ribosylation", "d": ["The process of removing one or more ADP-ribose residues from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0043111", "l": "replication fork arrest", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0043940", "l": "regulation of sexual sporulation resulting in formation of a cellular spore", "d": ["Any process that modulates the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010289", "l": "homogalacturonan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the pectidic homogalacturonan, characterized by a backbone of (1->4)-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0090100", "l": "positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway", "d": ["Any process that increases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0106104", "l": "regulation of glutamate receptor clustering", "d": ["Any process that modulates the frequency, rate or extent of glutamate receptor clustering."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0018965", "l": "s-triazine compound metabolic process", "d": ["The chemical reactions and pathways involving any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033020", "l": "cyclopentanol metabolic process", "d": ["The chemical reactions and pathways involving cyclopentanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061233", "l": "mesonephric glomerular basement membrane development", "d": ["The process whose specific outcome is the progression of the mesonephric glomerular basement membrane over time, from its formation to the mature structure. The mesonephric glomerular basement membrane is the basal laminal portion of the mesonephric glomerulus which performs the actual filtration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0042177", "l": "negative regulation of protein catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0098711", "l": "iron ion import across plasma membrane", "d": ["The directed movement of iron ions from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070172", "l": "positive regulation of tooth mineralization", "d": ["Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901320", "l": "negative regulation of heart induction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of heart induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902497", "l": "iron-sulfur cluster transmembrane transport", "d": ["A process in which an iron-sulfur cluster is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901820", "l": "alpha-zeacarotene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alpha-zeacarotene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902350", "l": "cellular response to chloroquine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901416", "l": "regulation of response to ethanol", "d": ["Any process that modulates the frequency, rate or extent of response to ethanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0150201", "l": "positive regulation of transport across blood-brain barrier", "d": ["Any process that activates or increases the frequency, rate or extent of transport across blood-brain barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903147", "l": "negative regulation of autophagy of mitochondrion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradation by autophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905415", "l": "positive regulation of dense core granule exocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of dense core granule exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0051928", "l": "positive regulation of calcium ion transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061930", "l": "regulation of erythrocyte enucleation", "d": ["Any process that modulates the frequency, rate or extent of erythrocyte enucleation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010620", "l": "negative regulation of transcription by transcription factor catabolism", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045690", "l": "positive regulation of antipodal cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of antipodal cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904030", "l": "negative regulation of cyclin-dependent protein kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cyclin-dependent protein kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0002793", "l": "positive regulation of peptide secretion", "d": ["Any process that activates or increases the frequency, rate, or extent of peptide secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002930", "l": "trabecular meshwork development", "d": ["The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.58067244181575", "identifiers": [{"i": "GO:0002443", "l": "leukocyte mediated immunity", "d": ["Any process involved in the carrying out of an immune response by a leukocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061944", "l": "negative regulation of protein K48-linked ubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of K48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904775", "l": "positive regulation of ubiquinone biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ubiquinone biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035149", "l": "lumen formation, open tracheal system", "d": ["Creation of the central hole of a tube in an open tracheal system through which gases flow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0052703", "l": "cellular modified histidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016546", "l": "male courtship behavior, proboscis-mediated licking", "d": ["The process during courtship where the male fly licks the genitalia of a stationary female fly with his proboscis. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061881", "l": "positive regulation of anterograde axonal transport of mitochondrion", "d": ["Any process that activates or increasesthe frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0031382", "l": "mating projection formation", "d": ["The aggregation, arrangement and bonding together of a set of components to form a cell projection in response to mating pheromone. This process is observed in unicellular fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062075", "l": "pollen aperture formation", "d": ["The cellular component assembly process of forming pollen apertures, areas where exine is reduced or absent, in the pollen cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0035931", "l": "mineralocorticoid secretion", "d": ["The regulated release of any mineralocorticoid into the circulatory system. Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014034", "l": "neural crest cell fate commitment", "d": ["The process in which a cell becomes committed to become a neural crest cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019476", "l": "D-lysine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003210", "l": "cardiac atrium formation", "d": ["The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014049", "l": "positive regulation of glutamate secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905812", "l": "regulation of motor neuron axon guidance", "d": ["Any process that modulates the frequency, rate or extent of motor neuron axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901829", "l": "zeaxanthin bis(beta-D-glucoside) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of zeaxanthin bis(beta-D-glucoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1905772", "l": "positive regulation of mesodermal cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1903798", "l": "regulation of miRNA processing", "d": ["Any process that modulates the frequency, rate or extent of microRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018865", "l": "acrylonitrile metabolic process", "d": ["The chemical reactions and pathways involving acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904324", "l": "negative regulation of inhibitory G protein-coupled receptor phosphorylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905325", "l": "regulation of meiosis I spindle assembly checkpoint", "d": ["Any process that modulates the frequency, rate or extent of the meiosis I spindle assembly checkpoint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003109", "l": "positive regulation of the force of heart contraction by circulating norepinephrine", "d": ["The process in which the secretion of norepinephrine into the bloodstream modulates the force of heart muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015940", "l": "pantothenate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061736", "l": "engulfment of target by autophagosome", "d": ["The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033477", "l": "S-methylmethionine metabolic process", "d": ["The chemical reactions and pathways involving S-methyl-methionine (SMM). SMM can be converted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090324", "l": "negative regulation of oxidative phosphorylation", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0052055", "l": "modulation by symbiont of host molecular function", "d": ["The process in which an organism effects a change in the function of a host protein via a direct interaction. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018241", "l": "protein O-linked glycosylation via hydroxylysine", "d": ["The glycosylation of protein via the O5 atom of peptidyl-hydroxylysine, forming O5-glycosyl-L-hydroxylysine; the most common form is galactosyl hydroxylysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062095", "l": "endoplasmic reticulum-peroxisome tethering", "d": ["The attachment of an endoplasmic reticulum membrane to a peroxisome via molecular tethers that physically bridge the two membranes and attach them to each other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900228", "l": "regulation of single-species biofilm formation in or on host organism", "d": ["Any process that modulates the frequency, rate or extent of single-species biofilm formation in or on host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071631", "l": "mating pheromone secretion involved in positive regulation of conjugation with cellular fusion", "d": ["The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that positively regulates a conjugation process that results in the union of cellular and genetic information from compatible mating types."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009444", "l": "pyruvate oxidation", "d": ["The chemical reactions and pathways resulting in the conversion of pyruvate to acetylphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140116", "l": "fluoride export across plasma membrane", "d": ["The directed movement of fluoride ions from inside of a cell, across the plasma membrane and into the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045671", "l": "negative regulation of osteoclast differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070795", "l": "positive regulation of conidiophore development", "d": ["Any process that activates or increases the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904872", "l": "regulation of telomerase RNA localization to Cajal body", "d": ["Any process that modulates the frequency, rate or extent of telomerase RNA localization to Cajal body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001170", "l": "negative regulation of ATP biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0014888", "l": "striated muscle adaptation", "d": ["Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:1903076", "l": "regulation of protein localization to plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of protein localization to plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0008090", "l": "retrograde axonal transport", "d": ["The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902330", "l": "synthesis of RNA primer involved in bacterial-type DNA replication", "d": ["Any synthesis of RNA primer that is involved in bacterial-type DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901179", "l": "spheroidene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of spheroidene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001714", "l": "endodermal cell fate specification", "d": ["The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an endoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.440173563602954", "identifiers": [{"i": "GO:0006837", "l": "serotonin transport", "d": ["The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0016102", "l": "diterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of diterpenoid compounds, terpenoids with four isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001995", "l": "norepinephrine-epinephrine catabolic process in blood stream", "d": ["The chemical reactions and pathways resulting in the breakdown of norepinephrine or epinephrine in the bloodstream."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0071453", "l": "cellular response to oxygen levels", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.794851102982726", "identifiers": [{"i": "GO:0009307", "l": "DNA restriction-modification system", "d": ["A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903998", "l": "regulation of eating behavior", "d": ["Any process that modulates the frequency, rate or extent of eating behavior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035320", "l": "imaginal disc-derived wing hair site selection", "d": ["Determination of the site in the cell of an imaginal disc-derived wing at which a prehair initiates outgrowth. Restriction of prehair initiation to the distalmost part of a cell is essential to ensure that each wing epithelial cell produces one adult hair that points distally."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003108", "l": "negative regulation of the force of heart contraction by chemical signal", "d": ["Any process which decreases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060338", "l": "regulation of type I interferon-mediated signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of a type I interferon-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000782", "l": "regulation of establishment of cell polarity regulating cell shape", "d": ["Any process that modulates the frequency, rate or extent of establishment of cell polarity regulating cell shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900458", "l": "negative regulation of brassinosteroid mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of brassinosteroid mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035912", "l": "dorsal aorta morphogenesis", "d": ["The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once."]}]}
{"type": "biolink:BiologicalProcess", "ic": "27.312504283229774", "identifiers": [{"i": "GO:0032501", "l": "multicellular organismal process", "d": ["Any biological process, occurring at the level of a multicellular organism, pertinent to its function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033004", "l": "negative regulation of mast cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035132", "l": "post-embryonic medial fin morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070537", "l": "histone H2A K63-linked deubiquitination", "d": ["A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a lysine residue in histone H2A or the variant H2AX."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0030317", "l": "flagellated sperm motility", "d": ["The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.470950656012619", "identifiers": [{"i": "GO:0030435", "l": "sporulation resulting in formation of a cellular spore", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990963", "l": "establishment of blood-retinal barrier", "d": ["Establishment of the barrier between the blood and the retina. The blood-retinal barrier is located at two levels, forming an outer barrier in the retinal pigment epithelium and an inner barrier in the endothelial membrane of the retinal vessels. Both these membranes have tight junctions of the 'nonleaky' type."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034265", "l": "isopentenyl adenine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the cytokinin 6-isopentenyladenine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060394", "l": "negative regulation of pathway-restricted SMAD protein phosphorylation", "d": ["Any process that decreases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001125", "l": "negative regulation of translational frameshifting", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of translational frameshifting."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0051583", "l": "dopamine uptake involved in synaptic transmission", "d": ["The directed movement of dopamine into a presynaptic neuron or glial cell. In this context, dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905080", "l": "negative regulation of cerebellar neuron development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cerebellar neuron development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.327400668044291", "identifiers": [{"i": "GO:0070828", "l": "heterochromatin organization", "d": ["Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002651", "l": "positive regulation of tolerance induction to self antigen", "d": ["Any process that activates or increases the frequency, rate, or extent of tolerance induction to self antigen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061680", "l": "Entner-Doudoroff pathway through gluconate to D-glyceraldehyde", "d": ["The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.535509353118186", "identifiers": [{"i": "GO:1905039", "l": "carboxylic acid transmembrane transport", "d": ["The process in which carboxylic acid is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904443", "l": "positive regulation of thyroid gland epithelial cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of thyroid gland epithelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904287", "l": "positive regulation of protein-pyridoxal-5-phosphate linkage", "d": ["Any process that activates or increases the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046856", "l": "phosphatidylinositol dephosphorylation", "d": ["The process of removing one or more phosphate groups from a phosphatidylinositol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:0016108", "l": "tetraterpenoid metabolic process", "d": ["The chemical reactions and pathways involving tetraterpenoid compounds, terpenoids with eight isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045317", "l": "equator specification", "d": ["The formation and development of the equator that forms the boundary between the photoreceptors in the dorsal sector of the eye and those in the ventral sector, dividing the eye into dorsal and ventral halves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1904424", "l": "regulation of GTP binding", "d": ["Any process that modulates the frequency, rate or extent of GTP binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.033057138195133", "identifiers": [{"i": "GO:0061540", "l": "octopamine secretion, neurotransmission", "d": ["The controlled release of octopamine by a cell, in which the octopamine acts as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000424", "l": "micromitophagy", "d": ["Degradation of a mitochondrion by lysosomal microautophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072441", "l": "response to meiotic DNA replication checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of meiotic DNA replication checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0031122", "l": "cytoplasmic microtubule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002503", "l": "peptide antigen assembly with MHC class II protein complex", "d": ["The binding of a peptide to the antigen binding groove of an MHC class II protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035208", "l": "positive regulation of hemocyte proliferation", "d": ["Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000962", "l": "positive regulation of mitochondrial RNA catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0018201", "l": "peptidyl-glycine modification", "d": ["The modification of peptidyl-glycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0000749", "l": "response to pheromone triggering conjugation with cellular fusion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that positively regulates the process of conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032083", "l": "negative regulation of type IV site-specific deoxyribonuclease activity", "d": ["Any process that stops or reduces the rate of type IV restriction endodeoxyribonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009097", "l": "isoleucine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001206", "l": "positive regulation of osteoclast development", "d": ["Any process that activates or increases the frequency, rate or extent of osteoclast development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035201", "l": "leg disc anterior/posterior lineage restriction", "d": ["Formation and/or maintenance of a lineage boundary between anterior and posterior compartments of the leg disc that cells cannot cross, thus separating the populations of cells in each compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048074", "l": "negative regulation of eye pigmentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006587", "l": "serotonin biosynthetic process from tryptophan", "d": ["The chemical reactions and pathways resulting in the formation from tryptophan of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.843307841253292", "identifiers": [{"i": "GO:0002285", "l": "lymphocyte activation involved in immune response", "d": ["A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902614", "l": "positive regulation of anti-Mullerian hormone signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of anti-Mullerian hormone signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061010", "l": "gallbladder development", "d": ["The progression of the gallbladder over time, from its initial formation to the mature structure. The gallbladder is a cavitated organ that stores bile."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0010026", "l": "trichome differentiation", "d": ["The process in which a relatively unspecialized epidermal cell acquires the specialized features of a trichome cell. An example of this process is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0032946", "l": "positive regulation of mononuclear cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051874", "l": "sphinganine-1-phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900331", "l": "negative regulation of methane biosynthetic process from trimethylamine", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from trimethylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002029", "l": "desensitization of G protein-coupled receptor signaling pathway", "d": ["The process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway after prolonged stimulation with an agonist of the pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043031", "l": "negative regulation of macrophage activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905017", "l": "positive regulation of isoleucine-tRNA ligase activity", "d": ["Any process that activates or increases the frequency, rate or extent of isoleucine-tRNA ligase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051776", "l": "detection of redox state", "d": ["The series of events in which a chemical stimulus indicating redox state is received and converted into a molecular signal. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032786", "l": "positive regulation of DNA-templated transcription, elongation", "d": ["Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0021903", "l": "rostrocaudal neural tube patterning", "d": ["The process in which the neural tube is divided into specific regions along the rostrocaudal axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033122", "l": "negative regulation of purine nucleotide catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010901", "l": "regulation of very-low-density lipoprotein particle remodeling", "d": ["Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030854", "l": "positive regulation of granulocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of granulocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061277", "l": "mesonephric nephron tubule formation", "d": ["The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900194", "l": "negative regulation of oocyte maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071639", "l": "positive regulation of monocyte chemotactic protein-1 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of monocyte chemotactic protein-1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061411", "l": "positive regulation of transcription from RNA polymerase II promoter in response to cold", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070680", "l": "asparaginyl-tRNAAsn biosynthesis via transamidation", "d": ["A tRNA aminoacylation process in which asparaginyl-tRNAAsn is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating aspartyl-tRNA synthetase generates the misacylated L-aspartyl-tRNAAsn species, and in the second step it is amidated to the correctly charged L-asparaginyl-tRNAAsn by the heterotrimeric aspartyl-tRNAAsn amidotransferase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036153", "l": "triglyceride acyl-chain remodeling", "d": ["Remodeling the acyl chains of triacylglycerol, through sequential deacylation and re-acylation reactions, to generate triacylglycerol containing different types of fatty acid acyl chains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032572", "l": "response to menaquinone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1902363", "l": "regulation of protein localization to spindle pole body", "d": ["Any process that modulates the frequency, rate or extent of protein localization to spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019876", "l": "nylon catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904711", "l": "regulation of Wnt-Frizzled-LRP5/6 complex assembly", "d": ["Any process that modulates the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0042590", "l": "antigen processing and presentation of exogenous peptide antigen via MHC class I", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1903044", "l": "protein localization to membrane raft", "d": ["A process in which a protein is transported to, or maintained in, a location within a membrane raft."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000291", "l": "regulation of myoblast proliferation", "d": ["Any process that modulates the frequency, rate or extent of myoblast proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:2000051", "l": "negative regulation of non-canonical Wnt signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044639", "l": "envenomation resulting in modulation of complement activation, lectin pathway in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the lectin pathway in the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071461", "l": "cellular response to redox state", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.741834732726957", "identifiers": [{"i": "GO:0006399", "l": "tRNA metabolic process", "d": ["The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060939", "l": "epicardium-derived cardiac fibroblast cell development", "d": ["The process whose specific outcome is the progression of an epicardial-derived cardiac fibroblast over time, from its formation to the mature state. A epicardial-derived cardiac fibroblast is a connective tissue cell of the heart that arises from the epicardium and secretes an extracellular matrix rich in collagen and other macromolecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0072423", "l": "response to DNA damage checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of DNA damage checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045004", "l": "DNA replication proofreading", "d": ["Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.853579598310013", "identifiers": [{"i": "GO:0045597", "l": "positive regulation of cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014858", "l": "positive regulation of skeletal muscle cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033498", "l": "galactose catabolic process via D-galactonate", "d": ["The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate D-galactonate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035739", "l": "CD4-positive, alpha-beta T cell proliferation", "d": ["The expansion of a CD4-positive, alpha-beta T cell population by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905346", "l": "protein localization to cleavage furrow rim", "d": ["A process in which a protein is transported to, or maintained in, a location within a cleavage furrow rim."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0018283", "l": "iron incorporation into metallo-sulfur cluster", "d": ["The incorporation of iron into a metallo-sulfur cluster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099576", "l": "regulation of protein catabolic process at postsynapse, modulating synaptic transmission", "d": ["Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903179", "l": "regulation of dopamine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of dopamine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002372", "l": "myeloid dendritic cell cytokine production", "d": ["Any process that contributes to cytokine production by a myeloid dendritic cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903142", "l": "positive regulation of establishment of endothelial barrier", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of endothelial barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021835", "l": "chemoattraction involved in embryonic olfactory bulb interneuron precursor migration", "d": ["The creation and reception of signals that result in the migration of interneuron precursors up a concentration gradient towards the olfactory bulb."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0003071", "l": "renal system process involved in regulation of systemic arterial blood pressure", "d": ["Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030581", "l": "symbiont intracellular protein transport in host", "d": ["The directed movement of a symbiont's proteins within a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033700", "l": "phospholipid efflux", "d": ["The directed movement of a phospholipid out of a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0034412", "l": "ascospore wall beta-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902948", "l": "negative regulation of tau-protein kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tau-protein kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0001115", "l": "protein-DNA-RNA complex organization", "d": ["Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA-RNA complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075053", "l": "penetration peg formation", "d": ["The assembly by the symbiont of a peg-like structure for the purpose of penetration into its host organism, which penetrates through the host cuticle and epidermal cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0001941", "l": "postsynaptic membrane organization", "d": ["A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097315", "l": "response to N-acetyl-D-glucosamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048075", "l": "positive regulation of eye pigmentation", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071596", "l": "ubiquitin-dependent protein catabolic process via the N-end rule pathway", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the N-end rule pathway. In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0045466", "l": "R7 cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of the R7 photoreceptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046944", "l": "protein carbamoylation", "d": ["The addition of a carbamoyl group to a protein amino acid. A carbamoyl group is the acyl group -CO-NH2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002549", "l": "negative regulation of plasma kallikrein-kinin cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the plasma kallikrein-kinin cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000801", "l": "negative regulation of endocardial cushion to mesenchymal transition involved in heart valve formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140469", "l": "GCN2-mediated signaling", "d": ["A series of reactions in which a signal is passed on to downstream proteins within the cell via GCN2 (also known as EIF2AK4), an intracellular protein kinase that is activated by stress signals, such as amino acid starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043417", "l": "negative regulation of skeletal muscle tissue regeneration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0060761", "l": "negative regulation of response to cytokine stimulus", "d": ["Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019919", "l": "peptidyl-arginine methylation, to asymmetrical-dimethyl arginine", "d": ["The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0039682", "l": "rolling circle viral DNA replication", "d": ["A process of unidirectional viral DNA replication that takes place on a circular DNA to rapidly produce numerous copies of the viral genome. Involves creating a nick in one strand of the circular DNA molecule at the origin of replication. DNA is then synthesized by DNA polymerase. Using the non-nicked strand as a template, replication proceeds around the circular DNA molecule, displacing the nicked strand as single-stranded DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903760", "l": "regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization", "d": ["Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902356", "l": "oxaloacetate(2-) transmembrane transport", "d": ["The directed movement of oxaloacetate(2-) across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901622", "l": "positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning", "d": ["Any process that activates or increases the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009732", "l": "detection of hexose stimulus", "d": ["The series of events in which a stimulus from a hexose is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072759", "l": "cellular response to topoisomerase inhibitor", "d": ["Any process that results in a change in state or activity of a (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048007", "l": "antigen processing and presentation, exogenous lipid antigen via MHC class Ib", "d": ["The process in which an antigen-presenting cell expresses lipid antigen of exogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072753", "l": "cellular response to glutathione", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000223", "l": "regulation of BMP signaling pathway involved in heart jogging", "d": ["Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in heart jogging."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048215", "l": "positive regulation of Golgi vesicle fusion to target membrane", "d": ["Any process that activates or increases the frequency, rate or extent of Golgi vesicle fusion to target membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:1902315", "l": "nuclear cell cycle DNA replication initiation", "d": ["Any DNA replication initiation that is involved in nuclear cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033025", "l": "regulation of mast cell apoptotic process", "d": ["Any process that modulates the frequency, rate, or extent of mast cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006682", "l": "galactosylceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000935", "l": "positive regulation of cellotriose metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellotriose metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903849", "l": "positive regulation of aorta morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of aorta morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0071266", "l": "'de novo' L-methionine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid, from simpler components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044345", "l": "stromal-epithelial cell signaling involved in prostate gland development", "d": ["The process of transferring information from a stromal cell to an epithelial cell where it is received and interpreted, as part of prostate gland development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018013", "l": "N-terminal peptidyl-glycine methylation", "d": ["The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035285", "l": "appendage segmentation", "d": ["Division of an appendage, an organ or part that is attached to the main body of an organism, into a series of semi-repetitive parts or segments. Most arthropod appendages, such as the legs and antennae, are visibly segmented."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905626", "l": "positive regulation of L-methionine import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of L-methionine import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019086", "l": "late viral transcription", "d": ["The transcription of the final group of viral genes of the viral life cycle, following middle transcription, or where middle transcription doesn't occur, following early transcription. Involves the transcription of genes encoding structural proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000376", "l": "RNA splicing, via transesterification reactions with guanosine as nucleophile", "d": ["Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0009832", "l": "plant-type cell wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellulose and pectin-containing cell wall. An example of this is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072036", "l": "mesenchymal to epithelial transition involved in renal vesicle formation", "d": ["A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075290", "l": "regulation of aplanospore formation", "d": ["Any process that modulates the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018417", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide", "d": ["The incorporation of iron into a 3Fe-2S cluster by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904291", "l": "positive regulation of mitotic DNA damage checkpoint", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic DNA damage checkpoint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033527", "l": "tetrapyrrole biosynthetic process from glycine and succinyl-CoA", "d": ["The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including glycine and succinyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.120403206680479", "identifiers": [{"i": "GO:0006304", "l": "DNA modification", "d": ["The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070329", "l": "tRNA seleno-modification", "d": ["The substitution of a selenium atom for a sulfur atom in a ribonucleotide in a tRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021942", "l": "radial glia guided migration of Purkinje cell", "d": ["The migration of postmitotic a Purkinje cell along radial glial cells from the ventricular zone to the Purkinje cell layer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006761", "l": "dihydrofolate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dihydrofolate, the dihydroxylated derivative of folate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0061055", "l": "myotome development", "d": ["The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098749", "l": "cerebellar neuron development", "d": ["The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046357", "l": "galactarate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of galactarate, the anion of galactaric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900394", "l": "regulation of kojic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of kojic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902130", "l": "(+)-lariciresinol metabolic process", "d": ["The chemical reactions and pathways involving (+)-lariciresinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0086004", "l": "regulation of cardiac muscle cell contraction", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle cell contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.958453806446542", "identifiers": [{"i": "GO:0044068", "l": "modulation by symbiont of host cellular process", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of a cellular process, any process that is carried out at the cellular level, but not necessarily restricted to a single cell, in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.232392044945293", "identifiers": [{"i": "GO:0051932", "l": "synaptic transmission, GABAergic", "d": ["The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043061", "l": "meiotic metaphase II plate congression", "d": ["The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019462", "l": "glutamine catabolic process to fumarate, using glutaminase", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with conversion of glutamine into glutamate catalyzed by the enzyme glutaminase (EC:3.5.1.2)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.470455508855807", "identifiers": [{"i": "GO:0071626", "l": "mastication", "d": ["The process of biting and mashing food with the teeth prior to swallowing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0031214", "l": "biomineral tissue development", "d": ["Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090077", "l": "foam cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002300", "l": "CD8-positive, alpha-beta intraepithelial T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0034377", "l": "plasma lipoprotein particle assembly", "d": ["The non-covalent aggregation and arrangement of proteins and lipids to form a plasma lipoprotein particle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002419", "l": "T cell mediated cytotoxicity directed against tumor cell target", "d": ["The directed killing of a tumor cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098874", "l": "spike train", "d": ["A series of sequential, propagated action potentials occurring in a single cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001134", "l": "methane biosynthetic process from carbon monoxide", "d": ["The chemical reactions and pathways resulting in the formation of a methane from a carbon monoxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0015827", "l": "tryptophan transport", "d": ["The directed movement of tryptophan, 2-amino-3-(1H-indol-3-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0031294", "l": "lymphocyte costimulation", "d": ["The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009401", "l": "phosphoenolpyruvate-dependent sugar phosphotransferase system", "d": ["The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070394", "l": "lipoteichoic acid metabolic process", "d": ["The chemical reactions and pathways involving lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070075", "l": "tear secretion", "d": ["The regulated release of the aqueous layer of the tear film from the lacrimal glands. Tears are the liquid product of a process of lacrimation to clean and lubricate the eyes. Tear fluid contains water, mucin, lipids, lysozyme, lactoferrin, lipocalin, lacritin, immunoglobulins, glucose, urea, sodium, and potassium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001720", "l": "conversion of lysyl-tRNA to pyrrolysyl-tRNA", "d": ["The modification process that results in the conversion of lysine, carried by a specialized lysine-accepting tRNA (possessing a CUA anticodon), to pyrrolysine (a lysine with an amide linkage to a (4R,5R)-4-substituted pyrroline-5-carboxylate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002615", "l": "positive regulation of monocyte antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061300", "l": "cerebellum vasculature development", "d": ["The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061060", "l": "negative regulation of peptidoglycan recognition protein signaling pathway", "d": ["Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904042", "l": "negative regulation of cystathionine beta-synthase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cystathionine beta-synthase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902483", "l": "cytotoxic T cell pyroptotic process", "d": ["Any pyroptotic process in a cytotoxic T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901112", "l": "actinorhodin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of actinorhodin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030997", "l": "regulation of centriole-centriole cohesion", "d": ["Any process that modulates the extent to which the two centrioles within a centrosome remain tightly paired; may be mediated by the assembly and disassembly of a proteinaceous linker."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070555", "l": "response to interleukin-1", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901273", "l": "2-dehydro-3-deoxy-D-gluconic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-dehydro-3-deoxy-D-gluconic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061218", "l": "negative regulation of mesonephros development", "d": ["Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045813", "l": "positive regulation of Wnt signaling pathway, calcium modulating pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072701", "l": "cellular response to bismuth", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905907", "l": "negative regulation of amyloid fibril formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amyloid fibril formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902111", "l": "response to diethyl maleate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0015693", "l": "magnesium ion transport", "d": ["The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0060700", "l": "regulation of ribonuclease activity", "d": ["Any process that modulates the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003133", "l": "endodermal-mesodermal cell signaling", "d": ["Any process that mediates the transfer of information from endodermal cells to mesodermal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0070314", "l": "G1 to G0 transition", "d": ["A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901671", "l": "positive regulation of superoxide dismutase activity", "d": ["Any process that activates or increases the frequency, rate or extent of superoxide dismutase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0035269", "l": "protein O-linked mannosylation", "d": ["The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl residue of a protein acceptor molecule, to form an O-linked protein-sugar linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061090", "l": "positive regulation of sequestering of zinc ion", "d": ["Any process that increases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1901441", "l": "poly(hydroxyalkanoate) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010743", "l": "regulation of macrophage derived foam cell differentiation", "d": ["Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.240853996207278", "identifiers": [{"i": "GO:1903828", "l": "negative regulation of protein localization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904178", "l": "negative regulation of adipose tissue development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0009261", "l": "ribonucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904952", "l": "hydroxycinnamic acid transport", "d": ["The directed movement of a hydroxycinnamic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0009106", "l": "lipoate metabolic process", "d": ["The chemical reactions and pathways involving lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904559", "l": "cellular response to dextromethorphan", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044313", "l": "protein K6-linked deubiquitination", "d": ["A protein deubiquitination process in which a K6-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is removed from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0019519", "l": "pentitol metabolic process", "d": ["The chemical reactions and pathways involving pentitols, any alditol with a chain of five carbon atoms in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0071901", "l": "negative regulation of protein serine/threonine kinase activity", "d": ["Any process that decreases the rate, frequency, or extent of protein serine/threonine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046544", "l": "development of secondary male sexual characteristics", "d": ["The process whose specific outcome is the progression of the secondary male sexual characteristics over time, from their formation to the mature structures. In male humans, these include growth of axillary, chest, and pubic hair, voice changes, and testicular/penile enlargement. Development occurs in response to sex hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006204", "l": "IMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of IMP, inosine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902418", "l": "(+)-abscisic acid D-glucopyranosyl ester transmembrane transport", "d": ["The process in which (+)-abscisic acid D-glucopyranosyl este is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010014", "l": "meristem initiation", "d": ["Initiation of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1901017", "l": "negative regulation of potassium ion transmembrane transporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032690", "l": "negative regulation of interleukin-1 alpha production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 alpha production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.392336866599784", "identifiers": [{"i": "GO:0051128", "l": "regulation of cellular component organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0060495", "l": "cell-cell signaling involved in lung development", "d": ["Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010336", "l": "gibberellic acid homeostasis", "d": ["Any biological process involved in the maintenance of an internal steady state of gibberellic acid; may involve transport, biosynthesis, catabolism or conjugation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061738", "l": "late endosomal microautophagy", "d": ["The autophagy process by which cytosolic proteins targeted for degradation are tagged with a chaperone and are directly transferred into and degraded in a late endosomal compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0051307", "l": "meiotic chromosome separation", "d": ["The process in which chromosomes are physically detached from each other during meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000397", "l": "positive regulation of ubiquitin-dependent endocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0018996", "l": "molting cycle, collagen and cuticulin-based cuticle", "d": ["The periodic shedding of part or all of a collagen and cuticulin-based cuticle, which is then replaced by a new collagen and cuticulin-based cuticle. An example of this is found in the Nematode worm, Caenorhabditis elegans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0038011", "l": "negative regulation of signal transduction by receptor internalization", "d": ["Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048818", "l": "positive regulation of hair follicle maturation", "d": ["Any process that activates or increases the frequency, rate or extent of hair follicle maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003162", "l": "atrioventricular node development", "d": ["The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042262", "l": "DNA protection", "d": ["Any process in which DNA is protected from damage by, for example, oxidative stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.724915096716916", "identifiers": [{"i": "GO:0006412", "l": "translation", "d": ["The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0019563", "l": "glycerol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039527", "l": "disruption by virus of host TRAF-mediated signal transduction", "d": ["Any process in which a virus interferes with TRAF-mediated signal transduction in the host."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0039520", "l": "induction by virus of host autophagy", "d": ["Any process in which a virus activates or increases the frequency, rate or extent of autophagy in the host."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902877", "l": "positive regulation of embryonic pattern specification", "d": ["Any process that activates or increases the frequency, rate or extent of embryonic pattern specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900667", "l": "regulation of endocrocin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of endocrocin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009666", "l": "plastid outer membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the outer membrane of a plastid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000560", "l": "positive regulation of CD24 production", "d": ["Any process that activates or increases the frequency, rate or extent of CD24 biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902689", "l": "negative regulation of NAD metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of NAD metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072743", "l": "cellular response to erythromycin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043310", "l": "negative regulation of eosinophil degranulation", "d": ["Any process that stops, prevents, or reduces the rate of eosinophil degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140256", "l": "negative regulation of cellular response to phosphate starvation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to phosphate starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904075", "l": "positive regulation of trophectodermal cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901096", "l": "regulation of autophagosome maturation", "d": ["Any process that modulates the frequency, rate or extent of autophagosome maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000557", "l": "regulation of immunoglobulin production in mucosal tissue", "d": ["Any process that modulates the frequency, rate or extent of immunoglobulin production in mucosal tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0060675", "l": "ureteric bud morphogenesis", "d": ["The process in which the ureteric bud is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0015771", "l": "trehalose transport", "d": ["The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Trehalose is a disaccharide isomeric with sucrose and obtained from certain lichens and fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035846", "l": "oviduct epithelium development", "d": ["The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042821", "l": "pyridoxal biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036360", "l": "sorocarp stalk morphogenesis", "d": ["The process in which the sorocarp stalk is generated and organized. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032680", "l": "regulation of tumor necrosis factor production", "d": ["Any process that modulates the frequency, rate or extent of tumor necrosis factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0061517", "l": "macrophage proliferation", "d": ["The expansion of a macrophage population by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901299", "l": "negative regulation of hydrogen peroxide-mediated programmed cell death", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030254", "l": "protein secretion by the type III secretion system", "d": ["The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0039696", "l": "RNA-templated viral transcription", "d": ["A transcription process that uses viral RNA as a template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901838", "l": "positive regulation of transcription of nucleolar large rRNA by RNA polymerase I", "d": ["Any process that activates or increases the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905116", "l": "positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore", "d": ["Any process that activates or increases the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0006220", "l": "pyrimidine nucleotide metabolic process", "d": ["The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000389", "l": "mRNA 3'-splice site recognition", "d": ["Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002397", "l": "MHC class I protein complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an MHC class I protein complex. Class I here refers to classical class I molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051037", "l": "regulation of transcription involved in meiotic cell cycle", "d": ["Any process that modulates the frequency, rate or extent of transcription as part of a meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901493", "l": "response to decalin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decalin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.459517078698049", "identifiers": [{"i": "GO:0050886", "l": "endocrine process", "d": ["The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006542", "l": "glutamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glutamine, 2-amino-4-carbamoylbutanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043686", "l": "co-translational protein modification", "d": ["The process of covalently altering one or more amino acids in a protein after translation has begun but before the protein has been released from the ribosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903805", "l": "L-valine import across plasma membrane", "d": ["The directed movement of L-valine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0060236", "l": "regulation of mitotic spindle organization", "d": ["Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0099050", "l": "vesicle scission", "d": ["The membrane scission process that is the final step in the formation of a vesicle, leading to separation from its parent membrane. Vesicle scission involves the constriction of a neck-forming protein complex, consisting e.g. of dynamin, around the budded membrane, leading to vesicle closure during its separation from the parent membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030300", "l": "regulation of intestinal cholesterol absorption", "d": ["Any process that modulates the frequency, rate or extent of absorption of cholesterol into the blood, and the exclusion of other sterols from absorption."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904279", "l": "regulation of transcription by RNA polymerase V", "d": ["Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase V."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.837016147763222", "identifiers": [{"i": "GO:0071695", "l": "anatomical structure maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061271", "l": "mesenchymal to epithelial transition involved in mesonephric renal vesicle formation", "d": ["A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007156", "l": "homophilic cell adhesion via plasma membrane adhesion molecules", "d": ["The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150068", "l": "positive regulation of tubulin deacetylase activity", "d": ["Any process that activates or increases the frequency, rate or extent of tubulin deacetylase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036305", "l": "ameloblast differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0098977", "l": "inhibitory chemical synaptic transmission", "d": ["Synaptic transmission that results in an inhibitory postsynaptic potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0019605", "l": "butyrate metabolic process", "d": ["The chemical reactions and pathways involving any butyrate, the anions of butyric acid (butanoic acid), a saturated, unbranched aliphatic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038012", "l": "negative regulation of Wnt signaling pathway by Wnt receptor internalization", "d": ["Any process in which internalization of a Wnt receptor stops, prevents, or reduces the frequency, rate or extent of Wnt signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062162", "l": "positive regulation of pyocyanine biosynthetic process", "d": ["Any process that increases the frequency, rate or extent of a pyocyanine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071348", "l": "cellular response to interleukin-11", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071982", "l": "maintenance of diapause", "d": ["The dormancy process that results an organism remaining in diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006846", "l": "acetate transport", "d": ["The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070153", "l": "mitochondrial leucyl-tRNA aminoacylation", "d": ["The process of coupling leucine to leucyl-tRNA in a mitochondrion, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140459", "l": "response to Gram-positive bacterium", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-positive bacterium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031666", "l": "positive regulation of lipopolysaccharide-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000032", "l": "regulation of secondary shoot formation", "d": ["Any process that modulates the frequency, rate or extent of secondary shoot formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046707", "l": "IDP metabolic process", "d": ["The chemical reactions and pathways involving IDP, inosine 5'-diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060906", "l": "negative regulation of regulatory ncRNA-mediated heterochromatin formation", "d": ["Any process that decreases the frequency, rate or extent of non-coding RNA-mediated heterochromatin formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002400", "l": "tolerance induction in nasopharyngeal-associated lymphoid tissue", "d": ["Tolerance induction taking place in the nasopharyngeal-associated lymphoid tissue (NALT)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:1905393", "l": "plant organ formation", "d": ["The process that gives rise to the plant organ. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905388", "l": "cellular response to beta-carotene", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071543", "l": "diphosphoinositol polyphosphate metabolic process", "d": ["The chemical reactions and pathways involving a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046078", "l": "dUMP metabolic process", "d": ["The chemical reactions and pathways involving dUMP, deoxyuridine (5'-)monophosphate (2'-deoxyuridine 5'-phosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.594043123901756", "identifiers": [{"i": "GO:0046541", "l": "saliva secretion", "d": ["The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051218", "l": "tungsten incorporation via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide)", "d": ["The incorporation of tungsten into a protein via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.920089577627991", "identifiers": [{"i": "GO:0090567", "l": "reproductive shoot system development", "d": ["The process whose specific outcome is the progression of a reproductive shoot system over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070610", "l": "regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019877", "l": "diaminopimelate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0032642", "l": "regulation of chemokine production", "d": ["Any process that modulates the frequency, rate, or extent of chemokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903009", "l": "proteasome complex disassembly", "d": ["The disaggregation of a proteasome complex into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0072131", "l": "kidney mesenchyme morphogenesis", "d": ["The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901200", "l": "negative regulation of calcium ion transport into cytosol involved in cellular response to salt stress", "d": ["Any negative regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0045023", "l": "G0 to G1 transition", "d": ["The mitotic cell cycle phase transition whose occurrence commits the cell from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033633", "l": "negative regulation of cell-cell adhesion mediated by integrin", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019545", "l": "arginine catabolic process to succinate", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including succinate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0042428", "l": "serotonin metabolic process", "d": ["The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:1903649", "l": "regulation of cytoplasmic transport", "d": ["Any process that modulates the frequency, rate or extent of cytoplasmic transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051466", "l": "positive regulation of corticotropin-releasing hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045968", "l": "negative regulation of juvenile hormone biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075032", "l": "negative regulation of formation of symbiont germ tube hook structure for appressorium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont germ tube hook structure formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.444551060876734", "identifiers": [{"i": "GO:0051048", "l": "negative regulation of secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0050873", "l": "brown fat cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0018210", "l": "peptidyl-threonine modification", "d": ["The modification of peptidyl-threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904874", "l": "positive regulation of telomerase RNA localization to Cajal body", "d": ["Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0050976", "l": "detection of mechanical stimulus involved in sensory perception of touch", "d": ["The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051674", "l": "localization of cell", "d": ["Any process in which a cell is transported to, and/or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0046146", "l": "tetrahydrobiopterin metabolic process", "d": ["The chemical reactions and pathways involving tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902393", "l": "negative regulation of exodeoxyribonuclease activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of exodeoxyribonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0051553", "l": "flavone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901597", "l": "response to carbendazim", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0010818", "l": "T cell chemotaxis", "d": ["The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1903888", "l": "regulation of plant epidermal cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of plant epidermal cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0003030", "l": "detection of hydrogen ion", "d": ["The series of events in which a hydrogen ion stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051463", "l": "negative regulation of cortisol secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of cortisol from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140434", "l": "positive regulation of protein localization to meiotic spindle pole body", "d": ["Any process that increases the frequency, rate or extent of protein localization to a meiotic spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019466", "l": "ornithine catabolic process via proline", "d": ["The chemical reactions and pathways resulting in the breakdown of ornithine, via the intermediate proline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002346", "l": "B cell positive selection", "d": ["Any process in which B cells are selected to survive based on signaling through the B cell antigen receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1903146", "l": "regulation of autophagy of mitochondrion", "d": ["Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905110", "l": "negative regulation of pulmonary blood vessel remodeling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pulmonary blood vessel remodeling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0021577", "l": "hindbrain structural organization", "d": ["The process that contributes to the act of creating the structural organization of the hindbrain. This process pertains to the physical shaping of a rudimentary structure. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002860", "l": "positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target", "d": ["Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090643", "l": "inflorescence phyllotactic patterning", "d": ["The radial pattern formation process that results in the formation of flowers around a central axis in an inflorescence meristem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072288", "l": "metanephric proximal tubule morphogenesis", "d": ["The process in which the anatomical structures of a metanephric proximal tubule are generated and organized. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010446", "l": "response to alkaline pH", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045849", "l": "negative regulation of nurse cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of nurse cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021557", "l": "oculomotor nerve development", "d": ["The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905026", "l": "positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097439", "l": "acquisition of desiccation tolerance", "d": ["The process in which tolerance to severe drying is acquired, before entering into a dry, either dormant or quiescent state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905319", "l": "mesenchymal stem cell migration", "d": ["The orderly movement of a mesenchymal stem cell from one site to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.414603710654305", "identifiers": [{"i": "GO:0061337", "l": "cardiac conduction", "d": ["Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901867", "l": "ecgonine methyl ester metabolic process", "d": ["The chemical reactions and pathways involving ecgonine methyl ester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903577", "l": "cellular response to L-arginine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010548", "l": "regulation of thylakoid membrane disassembly", "d": ["Any process that modulates the frequency, rate or extent of thylakoid membrane disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0006851", "l": "mitochondrial calcium ion transmembrane transport", "d": ["The process in which a calcium ion (Ca2+) is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903892", "l": "negative regulation of ATF6-mediated unfolded protein response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the ATF6-mediated unfolded protein response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0075343", "l": "modulation by symbiont of abscisic acid levels in host", "d": ["The alteration by an organism of the levels of abscisic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002301", "l": "CD4-positive, alpha-beta intraepithelial T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a CD4-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034760", "l": "negative regulation of iron ion transmembrane transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002624", "l": "positive regulation of B cell antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0008056", "l": "ocellus development", "d": ["The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043150", "l": "DNA synthesis involved in double-strand break repair via homologous recombination", "d": ["The synthesis of DNA that contributes to the process of double-strand break repair via homologous recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0030245", "l": "cellulose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043556", "l": "regulation of translation in response to oxidative stress", "d": ["Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904373", "l": "response to kainic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090210", "l": "regulation of establishment of blood-brain barrier", "d": ["Any process that modulates the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010593", "l": "negative regulation of lamellipodium assembly", "d": ["Any process that decreases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010353", "l": "response to trehalose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042838", "l": "D-glucarate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-glucarate, the D-enantiomer of glucarate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0031346", "l": "positive regulation of cell projection organization", "d": ["Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045213", "l": "neurotransmitter receptor metabolic process", "d": ["The chemical reactions and pathways involving neurotransmitter receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072197", "l": "ureter morphogenesis", "d": ["The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901007", "l": "(S)-scoulerine metabolic process", "d": ["The chemical reactions and pathways involving (S)-scoulerine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905790", "l": "regulation of mechanosensory behavior", "d": ["Any process that modulates the frequency, rate or extent of mechanosensory behavior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051352", "l": "negative regulation of ligase activity", "d": ["Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0046274", "l": "lignin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lignins, a class of polymers of phenylpropanoid units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001799", "l": "regulation of type IIb hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of type IIb hypersensitivity, a type of inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0046385", "l": "deoxyribose phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904366", "l": "negative regulation of chemokinesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chemokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.692830315749546", "identifiers": [{"i": "GO:0051338", "l": "regulation of transferase activity", "d": ["Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0001867", "l": "complement activation, lectin pathway", "d": ["Any process involved in the activation of any of the steps of the lectin pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021746", "l": "solitary nucleus development", "d": ["The process whose specific outcome is the progression of the solitary nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046356", "l": "acetyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032461", "l": "positive regulation of protein oligomerization", "d": ["Any process that activates or increases the frequency, rate or extent of protein oligomerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.888270688603868", "identifiers": [{"i": "GO:0008654", "l": "phospholipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051788", "l": "response to misfolded protein", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036506", "l": "maintenance of unfolded protein", "d": ["Maintaining a protein in an unfolded, soluble state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070220", "l": "aerobic sulfur oxidation", "d": ["A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase, and requires the presence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060637", "l": "positive regulation of lactation by mesenchymal-epithelial cell signaling", "d": ["The process that increases the rate, frequency, or extent of lactation as a result of the secretion of a signal from the mammary fat and its reception by a mammary epithelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0044856", "l": "plasma membrane raft localization", "d": ["Any process in which plasma membrane rafts are transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:2000756", "l": "regulation of peptidyl-lysine acetylation", "d": ["Any process that modulates the frequency, rate or extent of peptidyl-lysine acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051888", "l": "positive regulation of timing of exogen", "d": ["Any process that activates or increases the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.116918913335823", "identifiers": [{"i": "GO:0001659", "l": "temperature homeostasis", "d": ["A homeostatic process in which an organism modulates its internal body temperature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905921", "l": "regulation of acetylcholine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110137", "l": "regulation of imaginal disc-derived leg joint morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis, the process in which the anatomical structure of the imaginal disc-derived leg joint is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905297", "l": "positive regulation of neural crest cell fate specification", "d": ["Any process that activates or increases the frequency, rate or extent of neural crest cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901630", "l": "negative regulation of presynaptic membrane organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic membrane organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0060872", "l": "semicircular canal development", "d": ["The progression of the semicircular canal from its initial formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900350", "l": "positive regulation of methane biosynthetic process from methylamine", "d": ["Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010569", "l": "regulation of double-strand break repair via homologous recombination", "d": ["Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046221", "l": "pyridine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051891", "l": "positive regulation of cardioblast differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021553", "l": "olfactory nerve development", "d": ["The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "44.429316796539624", "identifiers": [{"i": "GO:0032940", "l": "secretion by cell", "d": ["The controlled release of a substance by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002203", "l": "proteolysis by cytosolic proteases associated with antigen processing and presentation", "d": ["The hydrolysis of a peptide bond or bonds within a protein by cytosolic resident proteases during antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0032634", "l": "interleukin-5 production", "d": ["The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003183", "l": "mitral valve morphogenesis", "d": ["The process in which the structure of the mitral valve is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097290", "l": "alpha-ribazole biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061278", "l": "epithelial cell migration involved in mesonephric nephron tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1905841", "l": "response to oxidopamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050861", "l": "positive regulation of B cell receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090364", "l": "regulation of proteasome assembly", "d": ["Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active proteasome complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901425", "l": "response to formic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.470455508855807", "identifiers": [{"i": "GO:0018958", "l": "phenol-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010078", "l": "maintenance of root meristem identity", "d": ["The process in which an organism retains a population of root meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905316", "l": "superior endocardial cushion morphogenesis", "d": ["The developmental process by which a superior endocardial cushion is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902254", "l": "negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0051222", "l": "positive regulation of protein transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090144", "l": "mitochondrial nucleoid organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid. The mitochondrial nucleoid is the region of a mitochondrion to which the DNA is confined."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010968", "l": "regulation of microtubule nucleation", "d": ["Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.235181147905195", "identifiers": [{"i": "GO:0008033", "l": "tRNA processing", "d": ["The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046586", "l": "regulation of calcium-dependent cell-cell adhesion", "d": ["Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902201", "l": "negative regulation of bacterial-type flagellum-dependent cell motility", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum-dependent cell motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1904978", "l": "regulation of endosome organization", "d": ["Any process that modulates the frequency, rate or extent of endosome organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905180", "l": "positive regulation of cardiac muscle tissue regeneration", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac muscle tissue regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0006549", "l": "isoleucine metabolic process", "d": ["The chemical reactions and pathways involving isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0030242", "l": "autophagy of peroxisome", "d": ["The process in which peroxisomes are delivered to a type of vacuole and degraded in response to changing nutrient conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0033673", "l": "negative regulation of kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0080091", "l": "regulation of raffinose metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving raffinose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.417489417432485", "identifiers": [{"i": "GO:0006479", "l": "protein methylation", "d": ["The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0106057", "l": "negative regulation of calcineurin-mediated signaling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcineurin-mediated signalling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110082", "l": "regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly", "d": ["Any process that modulates the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003212", "l": "cardiac left atrium morphogenesis", "d": ["The process in which the left cardiac atrium is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009731", "l": "detection of sucrose stimulus", "d": ["The series of events in which a sucrose stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070126", "l": "mitochondrial translational termination", "d": ["The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902854", "l": "positive regulation of nuclear migration during mitotic telophase", "d": ["Any process that activates or increases the frequency, rate or extent of nuclear migration during mitotic telophase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0051132", "l": "NK T cell activation", "d": ["The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901358", "l": "beta-D-galactofuranose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-D-galactofuranose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061622", "l": "glycolytic process through glucose-1-phosphate", "d": ["The chemical reactions and pathways through a glucose-1-phosphate intermediate that result in the catabolism of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003248", "l": "heart capillary growth", "d": ["The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0060976", "l": "coronary vasculature development", "d": ["The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045720", "l": "negative regulation of integrin biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000256", "l": "positive regulation of male germ cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of male germ cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0030647", "l": "aminoglycoside antibiotic metabolic process", "d": ["The chemical reactions and pathways involving an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904141", "l": "positive regulation of microglial cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of microglial cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0072583", "l": "clathrin-dependent endocytosis", "d": ["An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904215", "l": "regulation of protein import into chloroplast stroma", "d": ["Any process that modulates the frequency, rate or extent of protein import into chloroplast stroma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061934", "l": "regulation of adenine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of an adenine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901646", "l": "negative regulation of synoviocyte proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synoviocyte proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000184", "l": "positive regulation of progesterone biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042630", "l": "behavioral response to water deprivation", "d": ["Any process that results in a change in the behavior of an organism as a result of deprivation of water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0086014", "l": "atrial cardiac muscle cell action potential", "d": ["An action potential that occurs in an atrial cardiac muscle cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990936", "l": "vascular associated smooth muscle cell dedifferentiation", "d": ["The process in which a vascular smooth muscle cell (a non-striated, elongated, spindle-shaped cell found lining the blood vessels) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901447", "l": "positive regulation of response to propan-1-ol", "d": ["Any process that activates or increases the frequency, rate or extent of response to propan-1-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0031650", "l": "regulation of heat generation", "d": ["Any process that modulates the rate or extent of heat generation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0003206", "l": "cardiac chamber morphogenesis", "d": ["The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900221", "l": "regulation of amyloid-beta clearance", "d": ["Any process that modulates the frequency, rate or extent of amyloid-beta clearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903361", "l": "protein localization to basolateral plasma membrane", "d": ["Any process in which a protein is transported to, or maintained in, basolateral regions of the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002389", "l": "tolerance induction in Peyer's patch", "d": ["Tolerance induction taking place in the Peyer's patches."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034037", "l": "purine ribonucleoside bisphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010079", "l": "maintenance of vegetative meristem identity", "d": ["The process in which an organism retains a population of vegetative meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904630", "l": "cellular response to diterpene", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0002716", "l": "negative regulation of natural killer cell mediated immunity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035782", "l": "mature natural killer cell chemotaxis", "d": ["The directed movement of a mature natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). A mature natural killer cell is a natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class and other stress related molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072381", "l": "positive regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation", "d": ["Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072344", "l": "rescue of stalled ribosome", "d": ["A process of translational elongation that takes place when a ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032917", "l": "polyamine acetylation", "d": ["The modification of polyamines by addition of acetyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0019482", "l": "beta-alanine metabolic process", "d": ["The chemical reactions and pathways involving beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0052386", "l": "cell wall thickening", "d": ["A type of cell wall modification in which the cell wall is reinforced and made thicker."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050944", "l": "negative regulation of xanthophore differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of xanthophore differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097742", "l": "de novo centriole assembly", "d": ["Centriole assembly in which a centriole arises de novo, rather than by replication from an existing centriole. This process may occur via different mechanisms. Examples include the deuterosome pathway in multicilated epithelial animal cells and formation of centrioles during parthenogenesis in some insects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:0071852", "l": "fungal-type cell wall organization or biogenesis", "d": ["A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a fungal-type cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0031647", "l": "regulation of protein stability", "d": ["Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0060603", "l": "mammary gland duct morphogenesis", "d": ["The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010775", "l": "meiotic strand invasion involved in meiotic gene conversion", "d": ["The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051502", "l": "diterpene phytoalexin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of diterpene phytoalexins, terpenoids with 20 carbons produced by plants in response to environmental stresses."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0061804", "l": "mitotic spindle formation (spindle phase one)", "d": ["The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010961", "l": "intracellular magnesium ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of magnesium ions within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061170", "l": "negative regulation of hair follicle placode formation", "d": ["Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901827", "l": "zeaxanthin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of zeaxanthin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060971", "l": "embryonic heart tube left/right pattern formation", "d": ["The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.907222185088557", "identifiers": [{"i": "GO:0007017", "l": "microtubule-based process", "d": ["Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046204", "l": "nor-spermidine metabolic process", "d": ["The chemical reactions and pathways involving nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0018202", "l": "peptidyl-histidine modification", "d": ["The modification of peptidyl-histidine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:1903789", "l": "regulation of amino acid transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of amino acid transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0061028", "l": "establishment of endothelial barrier", "d": ["The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006287", "l": "base-excision repair, gap-filling", "d": ["Repair of the damaged strand by the combined action of an apurinic endouclease that degrades a few bases on the damaged strand and a polymerase that synthesizes a 'patch' in the 5' to 3' direction, using the undamaged strand as a template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903427", "l": "negative regulation of reactive oxygen species biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0051167", "l": "xylulose 5-phosphate metabolic process", "d": ["The chemical reactions and pathways involving xylulose 5-phosphate, a derivative of the ketopentose xylulose phosphorylated at the 5 carbon; it is an intermediate in the pentose phosphate pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007478", "l": "leg disc morphogenesis", "d": ["The process in which the anatomical structures derived from the leg disc are generated and organized. This includes the transformation of a leg imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the leg, coxa and ventral thoracic pleura."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905621", "l": "positive regulation of alpha-(1->3)-fucosyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071351", "l": "cellular response to interleukin-18", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007543", "l": "sex determination, somatic-gonadal interaction", "d": ["The process that mediates the interactions between somatic cells and gonadal cells that ultimately results in the specification of sexual status of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000276", "l": "negative regulation of oxidative phosphorylation uncoupler activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of oxidative phosphorylation uncoupler activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904401", "l": "cellular response to Thyroid stimulating hormone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1901856", "l": "negative regulation of cellular respiration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular respiration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000928", "l": "negative regulation of cellodextrin catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015009", "l": "corrin metabolic process", "d": ["The chemical reactions and pathways involving corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042705", "l": "ocellus photoreceptor cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a photoreceptor cell found in the ocellus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900045", "l": "negative regulation of protein K63-linked ubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked ubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0014023", "l": "neural rod formation", "d": ["The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090006", "l": "regulation of linear element assembly", "d": ["Any process that modulates the rate, frequency or extent of linear element assembly. Linear element assembly is the cell cycle process in which a proteinaceous scaffold, related to the synaptonemal complex, is assembled in association with S. pombe chromosomes during meiotic prophase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043143", "l": "regulation of translation by machinery localization", "d": ["Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097601", "l": "retina blood vessel maintenance", "d": ["A retina homeostatic process preventing the degeneration of a retina blood vessel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0033033", "l": "negative regulation of myeloid cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030965", "l": "plasma membrane electron transport, NADH to quinone", "d": ["The transfer of electrons from NADH to the quinone pool that occurs during oxidative phosphorylation and results in the generation of a proton gradient, mediated by the enzyme known as NADH-quinone oxidoreductase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002052", "l": "positive regulation of neuroblast proliferation", "d": ["Any process that activates or increases the rate of neuroblast proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035776", "l": "pronephric proximal tubule development", "d": ["The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032327", "l": "W-molybdopterin cofactor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901938", "l": "(-)-exo-alpha-bergamotene metabolic process", "d": ["The chemical reactions and pathways involving (-)-exo-alpha-bergamotene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120012", "l": "intermembrane sphingolipid transfer", "d": ["The transport of sphingolipids between membranes in which a sphingolipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032647", "l": "regulation of interferon-alpha production", "d": ["Any process that modulates the frequency, rate, or extent of interferon-alpha production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061874", "l": "positive regulation of hepatic stellate cell contraction", "d": ["Any process that activates or increases the frequency, rate or extent of hepatic stellate cell contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.34809373133632", "identifiers": [{"i": "GO:0016042", "l": "lipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032057", "l": "negative regulation of translational initiation in response to stress", "d": ["Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009244", "l": "lipopolysaccharide core region biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032063", "l": "negative regulation of translational initiation in response to osmotic stress", "d": ["Any process that stops, prevents or reduces the rate of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:1905476", "l": "negative regulation of protein localization to membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0051155", "l": "positive regulation of striated muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090071", "l": "negative regulation of ribosome biogenesis", "d": ["Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904912", "l": "positive regulation of establishment of RNA localization to telomere", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of RNA localization to telomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0009403", "l": "toxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904685", "l": "positive regulation of metalloendopeptidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903494", "l": "response to dehydroepiandrosterone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042353", "l": "fucose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fucose (6-deoxygalactose)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071494", "l": "cellular response to UV-C", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032882", "l": "regulation of chitin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0061217", "l": "regulation of mesonephros development", "d": ["Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905931", "l": "negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905194", "l": "positive regulation of chloroplast fission", "d": ["Any process that activates or increases the frequency, rate or extent of chloroplast fission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0016105", "l": "triterpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of triterpenoid compounds, terpenoids with six isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0018117", "l": "protein adenylylation", "d": ["The addition of an adenylyl group (adenosine 5'-monophosphate; AMP) to a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003329", "l": "pancreatic PP cell fate commitment", "d": ["The commitment of a cell to a pancreatic PP cell fate and its capacity to differentiate into a pancreatic PP cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1902473", "l": "regulation of protein localization to synapse", "d": ["Any process that modulates the frequency, rate or extent of protein localization to synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0014076", "l": "response to fluoxetine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0070664", "l": "negative regulation of leukocyte proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902783", "l": "cellular response to decane", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0052167", "l": "modulation by symbiont of host innate immune response", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000708", "l": "meiotic strand invasion", "d": ["The cell cycle process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This occurs during meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0039531", "l": "regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of a cytoplasmic pattern recognition receptor signaling pathway in response to a virus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0044321", "l": "response to leptin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism]."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006167", "l": "AMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0044785", "l": "metaphase/anaphase transition of meiotic cell cycle", "d": ["The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010763", "l": "positive regulation of fibroblast migration", "d": ["Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0000079", "l": "regulation of cyclin-dependent protein serine/threonine kinase activity", "d": ["Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0046496", "l": "nicotinamide nucleotide metabolic process", "d": ["The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinamide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032735", "l": "positive regulation of interleukin-12 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-12 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900662", "l": "negative regulation of emericellamide A biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide A biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0010712", "l": "regulation of collagen metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0050849", "l": "negative regulation of calcium-mediated signaling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009777", "l": "photosynthetic phosphorylation", "d": ["Any metabolic process in which photosynthetic organisms use light energy to convert ADP to ATP without the concomitant reduction of dioxygen (O2) to water that occurs in phosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018894", "l": "dibenzo-p-dioxin metabolic process", "d": ["The chemical reactions and pathways involving dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds. Dibenzo-p-dioxins are generated as by-products in the manufacturing of herbicides, insecticides, fungicides, paper pulp bleaching, and in incineration, and can accumulate in milk and throughout the food chain, creating significant health concern."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045062", "l": "extrathymic T cell selection", "d": ["The process of T cell selection that occurs in extrathymic locations, often resulting T cells of distinct specificities from those selected in the thymus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031551", "l": "regulation of brain-derived neurotrophic factor-activated receptor activity", "d": ["Any process that modulates the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097174", "l": "1,6-anhydro-N-acetyl-beta-muramic acid metabolic process", "d": ["The chemical reactions and pathways involving 1,6-anhydro-N-acetyl-beta-muramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902274", "l": "positive regulation of (R)-carnitine transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of (R)-carnitine transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010840", "l": "regulation of circadian sleep/wake cycle, wakefulness", "d": ["Any process that modulates the rate, frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905519", "l": "negative regulation of presynaptic active zone assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic active zone assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905689", "l": "positive regulation of diacylglycerol kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of diacylglycerol kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000492", "l": "box C/D snoRNP assembly", "d": ["The aggregation, arrangement and bonding together of proteins and a box C/D snoRNA to form a box C/D small nucleolar ribonucleoprotein (snoRNP) complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044619", "l": "positive regulation of relaxation of uterine smooth muscle in another organism", "d": ["The process in which an organism increases the extent of relaxation of smooth muscle in the uterus of a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046136", "l": "positive regulation of vitamin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051489", "l": "regulation of filopodium assembly", "d": ["Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006233", "l": "dTDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900735", "l": "positive regulation of flocculation", "d": ["Any process that activates or increases the frequency, rate or extent of flocculation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098887", "l": "neurotransmitter receptor transport, endosome to postsynaptic membrane", "d": ["The directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150102", "l": "negative regulation of monocyte activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of monocyte activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033497", "l": "sinapate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021845", "l": "neurotransmitter-mediated guidance of interneurons involved in substrate-independent cerebral cortex tangential migration", "d": ["The response of migrating interneurons to neurotransmitters that alter electrical activity in cells in calcium dependent manner."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150033", "l": "negative regulation of protein localization to lysosome", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.192299713551584", "identifiers": [{"i": "GO:0050954", "l": "sensory perception of mechanical stimulus", "d": ["The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019505", "l": "resorcinol metabolic process", "d": ["The chemical reactions and pathways involving resorcinol (C6H4(OH)2), a benzene derivative with many applications, including dyes, explosives, resins and as an antiseptic."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061734", "l": "parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization", "d": ["A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin-family molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061115", "l": "lung proximal/distal axis specification", "d": ["The establishment, maintenance and elaboration of the proximal/distal axis of the lung. The proximal/distal axis of the lung is defined by a line that runs from the trachea to the alveoli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014908", "l": "myotube differentiation involved in skeletal muscle regeneration", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0015977", "l": "carbon fixation", "d": ["A metabolic process in which carbon (usually derived from carbon dioxide) is incorporated into organic compounds (usually carbohydrates)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0036162", "l": "oxytocin production", "d": ["The appearance of oxytocin, a cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG, due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Oxytocin is the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary, and together with the neuropeptide vasopressin, is believed to influence social cognition and behavior. It also acts as a neurotransmitter in the brain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042243", "l": "asexual spore wall assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an asexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in Bacterial and Fungal species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032628", "l": "interleukin-24 production", "d": ["The appearance of interleukin-24 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035624", "l": "receptor transactivation", "d": ["The process in which a receptor is activated by another receptor. Receptor transactivation can occur through different mechanisms and includes cross-talk between signaling pathways where one receptor activates a receptor for a different ligand, and also activation of subunits within a receptor oligomer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0062173", "l": "brexanolone metabolic process", "d": ["The chemical reactions and pathways by which living organisms transform brexanolone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900470", "l": "positive regulation of phosphatidylserine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylserine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046343", "l": "streptomycin metabolic process", "d": ["The chemical reactions and pathways involving streptomycin, a commonly used antibiotic in cell culture media. It acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075283", "l": "sporulation resulting in formation of a multicellular or syncytial spore", "d": ["The process whose specific outcome is the progression of a multicellular or syncytial spore via septations over time, from its initiation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033615", "l": "mitochondrial proton-transporting ATP synthase complex assembly", "d": ["The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the mitochondrial inner membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140423", "l": "effector-mediated suppression of host pattern-triggered immunity signaling", "d": ["A process mediated by a molecule secreted by a symbiont that results in the suppression of a pattern-triggered immunity PTI signaling pathway. PTI signaling pathways are found in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000561", "l": "regulation of CD4-positive, alpha-beta T cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.151924274517057", "identifiers": [{"i": "GO:0002520", "l": "immune system development", "d": ["The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022009", "l": "central nervous system vasculogenesis", "d": ["The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002843", "l": "regulation of tolerance induction to tumor cell", "d": ["Any process that modulates the frequency, rate, or extent of tolerance induction to tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010358", "l": "leaf shaping", "d": ["The developmental process that pertains to the organization of a leaf in three-dimensional space once the structure has initially formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0008407", "l": "chaeta morphogenesis", "d": ["The process in which the anatomical structures of the chaeta are generated and organized. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006880", "l": "intracellular sequestering of iron ion", "d": ["The process of binding or confining iron ions in an intracellular area such that they are separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904033", "l": "negative regulation of t-SNARE clustering", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of t-SNARE clustering."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070179", "l": "D-serine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. D-serine is often formed by racemization of L-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901886", "l": "2-hydroxybenzoyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-hydroxybenzoyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051245", "l": "negative regulation of cellular defense response", "d": ["Any process that stops, prevents, or reduces the rate of the cellular defense response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032619", "l": "interleukin-16 production", "d": ["The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072293", "l": "specification of metanephric nephron tubule identity", "d": ["The process in which the tubules arranged along the proximal/distal axis of the metanephric nephron acquire their identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021565", "l": "accessory nerve development", "d": ["The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0008208", "l": "C21-steroid hormone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070911", "l": "global genome nucleotide-excision repair", "d": ["The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000496", "l": "negative regulation of cell proliferation involved in compound eye morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.468544520863134", "identifiers": [{"i": "GO:0051273", "l": "beta-glucan metabolic process", "d": ["The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099002", "l": "viral genome ejection through host cell envelope, short tail mechanism", "d": ["Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a short tail ejection system consisting a central tube, the connector which attaches the tail to the phage capsid and releases inner core proteins. Upon binding to the host cell surface, the phage displays a tube-like extension of its short tail that penetrates both host membranes. This tail extension comes from the release of viral core proteins with channel forming properties."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0032869", "l": "cellular response to insulin stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080169", "l": "cellular response to boron-containing substance deprivation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of boron obtained from boron-containing substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060770", "l": "negative regulation of epithelial cell proliferation involved in prostate gland development", "d": ["Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007529", "l": "establishment of synaptic specificity at neuromuscular junction", "d": ["The biological process in which a synapse between a motor neuron and a muscle is initially formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904155", "l": "DN2 thymocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a DN2 thymocyte. A DN2 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25-."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903167", "l": "regulation of pyrroline-5-carboxylate reductase activity", "d": ["Any process that modulates the frequency, rate or extent of pyrroline-5-carboxylate reductase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903907", "l": "negative regulation of plasma membrane raft polarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane raft polarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0033555", "l": "multicellular organismal response to stress", "d": ["Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903596", "l": "regulation of gap junction assembly", "d": ["Any process that modulates the frequency, rate or extent of gap junction assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019308", "l": "dTDP-mannose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.866234286307446", "identifiers": [{"i": "GO:0050909", "l": "sensory perception of taste", "d": ["The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052837", "l": "thiazole biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902814", "l": "positive regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry", "d": ["Any process that activates or increases the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044849", "l": "estrous cycle", "d": ["A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035313", "l": "wound healing, spreading of epidermal cells", "d": ["The migration of an epidermal cell along or through a wound gap that contributes to the reestablishment of a continuous epidermis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905504", "l": "negative regulation of motile cilium assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160028", "l": "negative regulation of pyroptosis", "d": ["Any process that decreases the frequency, rate or extent of pyroptosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0036176", "l": "response to neutral pH", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:2000846", "l": "regulation of corticosteroid hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of corticosteroid hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003148", "l": "outflow tract septum morphogenesis", "d": ["The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0033280", "l": "response to vitamin D", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019536", "l": "vibriobactin metabolic process", "d": ["The chemical reactions and pathways involving vibriobactin, the major siderophore produced by Vibrio cholerae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015903", "l": "fluconazole transport", "d": ["The directed movement of fluconazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0039687", "l": "viral DNA strand displacement replication", "d": ["A viral DNA replication process where only one strand is replicated at once, and which releases a single stranded DNA (ssDNA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901525", "l": "negative regulation of mitophagy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031035", "l": "myosin filament disassembly", "d": ["The disassembly of a filament composed of myosin molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904639", "l": "cellular response to resveratrol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0031033", "l": "myosin filament organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901751", "l": "leukotriene A4 metabolic process", "d": ["The chemical reactions and pathways involving leukotriene A4."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060194", "l": "regulation of antisense RNA transcription", "d": ["Any process that modulates the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150023", "l": "apical dendrite arborization", "d": ["The process in which the anatomical structures of a dendritic tree are generated on the apical neuron side and organized into dendritic branches."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032712", "l": "negative regulation of interleukin-3 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-3 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904824", "l": "anaphase-promoting complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an anaphase-promoting complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0045292", "l": "mRNA cis splicing, via spliceosome", "d": ["The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006463", "l": "steroid hormone receptor complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a steroid hormone receptor complex, an intracellular receptor that binds steroid hormones. The complex is often a dimer, and forms after the steroid has bound the receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0000821", "l": "regulation of arginine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903873", "l": "negative regulation of DNA recombinase mediator complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA recombinase mediator complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010992", "l": "ubiquitin recycling", "d": ["Any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell by recycling ubiquitin from proteasome-bound ubiquitinated intermediates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905815", "l": "regulation of dorsal/ventral axon guidance", "d": ["Any process that modulates the frequency, rate or extent of dorsal/ventral axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042663", "l": "regulation of endodermal cell fate specification", "d": ["Any process that mediates the specification of a cell into an endoderm cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034354", "l": "'de novo' NAD biosynthetic process from tryptophan", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071931", "l": "positive regulation of transcription involved in G1/S transition of mitotic cell cycle", "d": ["Any process that activates or increases transcription as part of the G1/S transition of the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071476", "l": "cellular hypotonic response", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019612", "l": "4-toluenecarboxylate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045209", "l": "MAPK phosphatase export from nucleus, leptomycin B sensitive", "d": ["Leptomycin B-sensitive movement of a MAPK phosphatase from the nucleus to the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905848", "l": "positive regulation of cellular response to oxidopamine", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to oxidopamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0014812", "l": "muscle cell migration", "d": ["The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001836", "l": "release of cytochrome c from mitochondria", "d": ["The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070836", "l": "caveola assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a caveola. A caveola is a plasma membrane raft that forms a small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0001742", "l": "oenocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an oenocyte. Oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.117553355927669", "identifiers": [{"i": "GO:0008610", "l": "lipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003385", "l": "cell-cell signaling involved in amphid sensory organ development", "d": ["Any process that mediates the transfer of information from one cell to another and contributes to the progression of an amphid sensory organ over time, from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902800", "l": "positive regulation of phosphodiesterase I activity", "d": ["Any process that activates or increases the frequency, rate or extent of phosphodiesterase I activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001886", "l": "endothelial cell morphogenesis", "d": ["The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903324", "l": "negative regulation of snoRNA metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051979", "l": "alginic acid acetylation", "d": ["The addition of O-acetyl ester groups to alginic acid, a linear polymer of D-mannuronate and L-guluronate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006236", "l": "cytidine salvage", "d": ["Any process that generates cytidine, cytosine riboside, from derivatives of it without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150066", "l": "negative regulation of deacetylase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of deacetylase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0110002", "l": "regulation of tRNA methylation", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA methylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0090605", "l": "submerged biofilm formation", "d": ["A process in which planktonically growing microorganisms aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018943", "l": "organotin metabolic process", "d": ["The chemical reactions and pathways involving organotin, an organic compound containing a tin atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0140058", "l": "neuron projection arborization", "d": ["The process in which the anatomical structures of a neuron projection are generated and organized into branches. A neuron projection is any process extending from a neural cell, such as axons or dendrites."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046208", "l": "spermine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062055", "l": "photosynthetic state transition", "d": ["A regulation of the phtosynthetic light reaction in which the light harvesting antenna complexes transition between photosystems."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000926", "l": "positive regulation of cellodextrin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellodextrin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006212", "l": "uracil catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060938", "l": "epicardium-derived cardiac fibroblast cell differentiation", "d": ["The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990478", "l": "response to ultrasound", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultrasonic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035481", "l": "positive regulation of Notch signaling pathway involved in heart induction", "d": ["Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900082", "l": "negative regulation of arginine catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of arginine catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903396", "l": "negative regulation of secondary cell septum biogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell septum biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0010002", "l": "cardioblast differentiation", "d": ["The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035781", "l": "CD86 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CD86, a CD marker that occurs on antigen presenting cells that provides co-stimulatory signals necessary for T cell activation and survival."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060459", "l": "left lung development", "d": ["The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903185", "l": "L-dopa biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-dopa."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070156", "l": "mitochondrial phenylalanyl-tRNA aminoacylation", "d": ["The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038176", "l": "positive regulation of SREBP signaling pathway in response to decreased oxygen levels", "d": ["Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway in response to a decrease in oxygen levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002425", "l": "tolerance induction in urogenital tract", "d": ["Tolerance induction taking place in the urogenital tract."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902842", "l": "negative regulation of netrin-activated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of netrin-activated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901422", "l": "response to butan-1-ol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butan-1-ol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905088", "l": "positive regulation of synaptonemal complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of synaptonemal complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0098900", "l": "regulation of action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003087", "l": "positive regulation of the force of heart contraction by neuronal epinephrine", "d": ["The process in which the release of epinephrine from nerve endings modulates the force of heart muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016346", "l": "male meiotic chromosome movement towards spindle pole", "d": ["The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during male meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0042749", "l": "regulation of circadian sleep/wake cycle", "d": ["Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903818", "l": "positive regulation of voltage-gated potassium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070060", "l": "'de novo' actin filament nucleation", "d": ["The actin nucleation process in which actin monomers combine in the absence of any existing actin filaments; elongation of the actin oligomer formed by nucleation leads to the formation of an unbranched filament."]}]}
{"type": "biolink:BiologicalProcess", "ic": "15.433078976890707", "identifiers": [{"i": "GO:0008150", "l": "biological_process", "d": ["A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.", "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046926", "l": "peptide cross-linking via 2-(S-L-cysteinyl)-D-allo-threonine", "d": ["The post-translational cross-linking of a cysteine residue to an L-threonine residue to form 2-(S-L-cysteinyl)-D-allo-threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061453", "l": "interstitial cell of Cajal differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0051319", "l": "G2 phase", "d": ["The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044865", "l": "negative regulation by virus of host cell division", "d": ["Any process where an infecting virus stops, prevents, or reduces the frequency, rate or extent of its host's cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010807", "l": "regulation of synaptic vesicle priming", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0097688", "l": "glutamate receptor clustering", "d": ["The neurotransmitter-gated ion channel clustering process in which glutamate receptors are localized to distinct domains in the cell membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.685364931984026", "identifiers": [{"i": "GO:0051304", "l": "chromosome separation", "d": ["The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0000429", "l": "carbon catabolite regulation of transcription from RNA polymerase II promoter", "d": ["A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090603", "l": "sieve element differentiation", "d": ["The process whereby a relatively unspecialized cell acquires specialized features of a sieve element."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002866", "l": "positive regulation of acute inflammatory response to antigenic stimulus", "d": ["Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015890", "l": "nicotinamide mononucleotide transport", "d": ["The directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of D-ribose. It is a constituent of NAD and NADP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902194", "l": "2-methylbut-2-enoyl-CoA(4-) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 2-methylbut-2-enoyl-CoA(4-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.967140482697559", "identifiers": [{"i": "GO:0030258", "l": "lipid modification", "d": ["The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000759", "l": "regulation of N-terminal peptidyl-lysine acetylation", "d": ["Any process that modulates the frequency, rate or extent of N-terminal peptidyl-lysine acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0086050", "l": "membrane repolarization during bundle of His cell action potential", "d": ["The process in which ions are transported across a membrane such that the bundle of His cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061194", "l": "taste bud morphogenesis", "d": ["The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061130", "l": "pancreatic bud formation", "d": ["The morphogenetic process in which the foregut region specified to become the pancreas forms a bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010613", "l": "positive regulation of cardiac muscle hypertrophy", "d": ["Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014039", "l": "negative regulation of Schwann cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051688", "l": "maintenance of plastid location", "d": ["Any process in which a plastid is maintained in a specific location within a cell and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042920", "l": "3-hydroxyphenylpropionic acid transmembrane transport", "d": ["The directed movement of 3-hydroxyphenylpropionic acid across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0071385", "l": "cellular response to glucocorticoid stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902992", "l": "negative regulation of amyloid precursor protein catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amyloid precursor protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043252", "l": "sodium-independent organic anion transport", "d": ["The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0090351", "l": "seedling development", "d": ["The process whose specific outcome is the progression of the seedling over time, beginning with seed germination and ending when the first adult leaves emerge."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903285", "l": "positive regulation of hydrogen peroxide catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of hydrogen peroxide catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097503", "l": "sialylation", "d": ["The covalent attachment of sialic acid to a substrate molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010102", "l": "lateral root morphogenesis", "d": ["The process in which the anatomical structures of a lateral root are generated and organized. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.939870552020253", "identifiers": [{"i": "GO:0072594", "l": "establishment of protein localization to organelle", "d": ["The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904606", "l": "fat cell apoptotic process", "d": ["Any apoptotic process in a fat cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045848", "l": "positive regulation of nitrogen utilization", "d": ["Any process that activates or increases the frequency, rate or extent of nitrogen utilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905092", "l": "response to diosgenin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:1901642", "l": "nucleoside transmembrane transport", "d": ["The directed movement of nucleoside across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0048749", "l": "compound eye development", "d": ["The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009962", "l": "regulation of flavonoid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900892", "l": "positive regulation of pentadecane metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of pentadecane metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021933", "l": "radial glia guided migration of cerebellar granule cell", "d": ["The inward migration of postmitotic granule cells along a radial glial cell from the external granule layer to the internal granule cell layer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032871", "l": "regulation of karyogamy", "d": ["Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0018126", "l": "protein hydroxylation", "d": ["The addition of a hydroxy group to a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060686", "l": "negative regulation of prostatic bud formation", "d": ["Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904293", "l": "negative regulation of ERAD pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ERAD pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021542", "l": "dentate gyrus development", "d": ["The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071979", "l": "cytoskeleton-mediated cell swimming", "d": ["Cell motility in which contractile cytoskeletal elements alter cell shape, resulting in the smooth movement of a cell through a liquid medium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902069", "l": "negative regulation of sphingolipid mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sphingolipid signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0002514", "l": "B cell tolerance induction", "d": ["A process involving any mechanism for tolerance induction in B cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000024", "l": "maltose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0071894", "l": "histone H2B conserved C-terminal lysine ubiquitination", "d": ["A histone ubiquitination process in which a ubiquitin monomer is added to a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, and K120 in mammals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035845", "l": "photoreceptor cell outer segment organization", "d": ["A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014886", "l": "transition between slow and fast fiber", "d": ["The process of conversion of slow-contracting muscle fibers to a faster character. This may involve increasing of contractile rate, fast myosin gene induction, increase in glycolytic metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046338", "l": "phosphatidylethanolamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0032076", "l": "negative regulation of deoxyribonuclease activity", "d": ["Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075271", "l": "zygosporangium development", "d": ["The process in which a fruiting body called zygosporangium is formed. A zygosporangium is a thick-walled structure in which spores are produced, and is characteristic of the Zygomycetes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0055117", "l": "regulation of cardiac muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034078", "l": "butanediol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0036166", "l": "phenotypic switching", "d": ["A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:1901019", "l": "regulation of calcium ion transmembrane transporter activity", "d": ["Any process that modulates the frequency, rate or extent of calcium ion transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900997", "l": "benzene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of benzene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900587", "l": "arugosin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of arugosin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045036", "l": "protein targeting to chloroplast", "d": ["The process of directing proteins towards the chloroplast, usually using signals contained within the protein. Imported proteins are synthesized as cytosolic precursors containing N-terminal uptake-targeting sequences that direct each protein to its correct subcompartment and are subsequently cleaved."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000025", "l": "maltose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090128", "l": "regulation of synapse maturation", "d": ["Any process that modulates the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085015", "l": "dormancy maintenance of symbiont in host", "d": ["Any process in which a dormant state is maintained by the symbiont within the host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2001122", "l": "maltoheptaose metabolic process", "d": ["The chemical reactions and pathways involving a maltoheptaose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000240", "l": "diplotene", "d": ["The cell cycle phase which follows pachytene during prophase I of meiosis, during which the homologous chromosomes begin to separate and the synaptonemal complex dissolves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046630", "l": "gamma-delta T cell proliferation", "d": ["The expansion of a gamma-delta T cell population by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051470", "l": "ectoine transport", "d": ["The directed movement of ectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid) is a tetrahydropyrimidine commonly synthesized by halophilic bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034488", "l": "basic amino acid transmembrane export from vacuole", "d": ["The directed movement of basic amino acids out of the vacuole, across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000718", "l": "nucleotide-excision repair, DNA damage removal", "d": ["The removal of the oligonucleotide that contains the DNA damage. The oligonucleotide is formed by dual incisions that flank the site of DNA damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070657", "l": "neuromast regeneration", "d": ["The regrowth of a neuromast following its loss or destruction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034478", "l": "phosphatidylglycerol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphatidylglycerols, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902240", "l": "positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator", "d": ["Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0035213", "l": "clypeo-labral disc development", "d": ["The process whose specific outcome is the progression of the clypeo-labral disc over time, from its formation to the metamorphosis to form adult structures. The clypeo-labral disc develops into the labrum, anterior cibarial plate, fish trap bristles, epistomal sclerite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0051154", "l": "negative regulation of striated muscle cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:0031163", "l": "metallo-sulfur cluster assembly", "d": ["The incorporation of a metal and exogenous sulfur into a metallo-sulfur cluster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0043450", "l": "alkene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036445", "l": "neuronal stem cell division", "d": ["The self-renewing division of a neuronal stem cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036255", "l": "response to methylamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0010087", "l": "phloem or xylem histogenesis", "d": ["The process whose specific outcome is the progression of phloem and/or xylem over time, from formation to the mature structure. An example of this process is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0055006", "l": "cardiac cell development", "d": ["The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010241", "l": "ent-kaurene oxidation to kaurenoic acid", "d": ["The three successive oxidations of the 4-methyl group of ent-kaurene to form ent-kaur-16-en-19-oate, kaurenoic acid. This process may be carried out entirely by the enzyme ent-kaurene oxidase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900212", "l": "negative regulation of mesenchymal cell apoptotic process involved in metanephros development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060075", "l": "regulation of resting membrane potential", "d": ["Any process that modulates the establishment or extent of a resting potential, the electrical charge across the plasma membrane, with the interior of the cell negative with respect to the exterior. The resting potential is the membrane potential of a cell that is not stimulated to be depolarized or hyperpolarized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009143", "l": "nucleoside triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033468", "l": "CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060304", "l": "regulation of phosphatidylinositol dephosphorylation", "d": ["Any process that modulates the frequency, rate or extent of the chemical reaction involving the removal of one or more phosphate groups from a phosphatidylinositol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903380", "l": "positive regulation of mitotic chromosome condensation", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001012", "l": "mesenchymal cell differentiation involved in renal system development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018388", "l": "N-terminal peptidyl-valine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-valine", "d": ["The condensation of pyruvate through the 2-oxo group with the N-terminal valine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-valine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001312", "l": "lysobisphosphatidic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0090678", "l": "cell dedifferentiation involved in phenotypic switching", "d": ["A cell dedifferentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904692", "l": "positive regulation of type B pancreatic cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903618", "l": "regulation of transdifferentiation", "d": ["Any process that modulates the frequency, rate or extent of transdifferentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033600", "l": "negative regulation of mammary gland epithelial cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of mammary gland epithelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900337", "l": "negative regulation of methane biosynthetic process from carbon monoxide", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from carbon monoxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032298", "l": "positive regulation of DNA-templated DNA replication initiation", "d": ["Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000101", "l": "regulation of mammary stem cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of mammary stem cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003251", "l": "positive regulation of cell proliferation involved in heart valve morphogenesis", "d": ["Any process that increases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046680", "l": "response to DDT", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a DDT stimulus. DDT, dichlorodiphenyltrichloroethane, is a chlorinated hydrocarbon pesticide moderately toxic to humans and other animals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000390", "l": "negative regulation of neutrophil extravasation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901276", "l": "tartrate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tartrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046225", "l": "bacteriocin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036285", "l": "SAGA complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a SAGA complex, a SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904933", "l": "regulation of cell proliferation in midbrain", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation in midbrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072146", "l": "DCT cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a distal convoluted tubule cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900027", "l": "regulation of ruffle assembly", "d": ["Any process that modulates the frequency, rate or extent of ruffle assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002351", "l": "serotonin production involved in inflammatory response", "d": ["The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030418", "l": "nicotianamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0032252", "l": "secretory granule localization", "d": ["Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.725591100956891", "identifiers": [{"i": "GO:0045017", "l": "glycerolipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycerolipids, any lipid with a glycerol backbone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0051481", "l": "negative regulation of cytosolic calcium ion concentration", "d": ["Any process that decreases the concentration of calcium ions in the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043282", "l": "pharyngeal muscle development", "d": ["The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035778", "l": "pronephric nephron tubule epithelial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051599", "l": "response to hydrostatic pressure", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.586422797268227", "identifiers": [{"i": "GO:0042476", "l": "odontogenesis", "d": ["The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018403", "l": "protein-dermatan sulfate linkage via dermatan 4-sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine", "d": ["Dermatan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061692", "l": "cellular detoxification of hydrogen peroxide", "d": ["Any process that reduces or removes the toxicity of hydrogen peroxide in a cell. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010555", "l": "response to mannitol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0015867", "l": "ATP transport", "d": ["The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0016486", "l": "peptide hormone processing", "d": ["The generation of a mature peptide hormone by posttranslational processing of a prohormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060352", "l": "cell adhesion molecule production", "d": ["The appearance of a cell adhesion molecule due to biosynthesis or secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.367604042548066", "identifiers": [{"i": "GO:0006508", "l": "proteolysis", "d": ["The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0031112", "l": "positive regulation of microtubule polymerization or depolymerization", "d": ["Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007393", "l": "dorsal closure, leading edge cell fate determination", "d": ["The cell fate determination process in which a cell within the dorsal ectoderm becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009995", "l": "soluble molecule recognition", "d": ["The recognition of soluble molecules in the environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072276", "l": "metanephric glomerulus vasculature morphogenesis", "d": ["The process in which the anatomical structures of the metanephric glomerulus vasculature are generated and organized. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098958", "l": "retrograde axonal transport of mitochondrion", "d": ["The directed movement of mitochondria along microtubules in axons towards the cell body and away from the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060398", "l": "regulation of growth hormone receptor signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0051511", "l": "negative regulation of unidimensional cell growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905930", "l": "regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching", "d": ["Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0062126", "l": "fatty acid primary amide metabolic process", "d": ["The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform primary fatty amides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0050844", "l": "peptidyl-selenocysteine modification", "d": ["The modification of peptidyl-selenocysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003174", "l": "mitral valve development", "d": ["The progression of the mitral valve over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905210", "l": "regulation of fibroblast chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of fibroblast chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036016", "l": "cellular response to interleukin-3", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.618854952666041", "identifiers": [{"i": "GO:0055082", "l": "intracellular chemical homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of a chemical within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060937", "l": "cardiac fibroblast cell fate commitment", "d": ["The commitment of cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0150115", "l": "cell-substrate junction organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-substrate junction. A cell-substrate junction is a specialized region of connection between a cell and the extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090314", "l": "positive regulation of protein targeting to membrane", "d": ["Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002188", "l": "translation reinitiation", "d": ["A gene-specific translational control mechanism where the small ribosomal subunit remains attached to the mRNA following termination of translation, then resumes scanning on the same mRNA molecule and initiates again at a downstream start site. Reinitiation depends on de novo recruitment of the ternary complex that is required to recognize the next AUG codon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090211", "l": "positive regulation of establishment of blood-brain barrier", "d": ["Any process that increases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001111", "l": "RNA polymerase II promoter clearance", "d": ["A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase II, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042190", "l": "vanillin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903546", "l": "protein localization to photoreceptor outer segment", "d": ["A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902910", "l": "positive regulation of melanosome transport", "d": ["Any process that activates or increases the frequency, rate or extent of melanosome transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1900107", "l": "regulation of nodal signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of nodal signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0048467", "l": "gynoecium development", "d": ["The process whose specific outcome is the progression of the gynoecium over time, from its formation to the mature structure. The gynoecium is the collective name for the carpels of a flower."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009902", "l": "chloroplast relocation", "d": ["The process in which chloroplasts in photosynthetic cells migrate toward illuminated sites to optimize photosynthesis and move away from excessively illuminated areas to protect the photosynthetic machinery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048526", "l": "imaginal disc-derived wing expansion", "d": ["The process of expanding or inflating the folded imaginal disc-derived pupal wing, and the adhering of the dorsal and ventral surfaces, to form the mature adult wing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042466", "l": "chemokinesis", "d": ["A response by a motile cell to a soluble chemical that involves an increase or decrease in speed (positive or negative orthokinesis) or of frequency of movement or a change in the frequency or magnitude of turning behavior (klinokinesis)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0065002", "l": "intracellular protein transmembrane transport", "d": ["The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0097064", "l": "ncRNA export from nucleus", "d": ["The directed movement of a non-coding RNA transcript (ncRNA) from the nucleus to the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061616", "l": "glycolytic process from fructose through fructose-6-phosphate", "d": ["The glycolytic process through fructose-6-phosphate in which fructose is catabolized into pyruvate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903569", "l": "positive regulation of protein localization to ciliary membrane", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035346", "l": "positive regulation of hypoxanthine transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0007476", "l": "imaginal disc-derived wing morphogenesis", "d": ["The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021811", "l": "growth factor signaling initiating cell movement involved in cerebral cortex radial glia guided migration", "d": ["Signaling between growth factors and their receptors that results in the start of cell movement, where this process is involved in glial-mediated radial migration in the cerebral cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1904478", "l": "regulation of intestinal absorption", "d": ["Any process that modulates the frequency, rate or extent of intestinal absorption."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021588", "l": "cerebellum formation", "d": ["The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1990947", "l": "exit from meiosis", "d": ["Any process involved in the progression from anaphase/telophase of meiosis II to the creation of end products of meiosis, in which ploidy is reduced by half."]}]}
{"type": "biolink:BiologicalProcess", "ic": "48.433639991482821", "identifiers": [{"i": "GO:0001505", "l": "regulation of neurotransmitter levels", "d": ["Any process that modulates levels of neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990672", "l": "medial-Golgi-derived vesicle fusion with Golgi trans cisterna membrane", "d": ["The joining of the lipid bilayer membrane around a medial-Golgi-derived vesicle to the lipid bilayer membrane around the Golgi trans cisterna. Vesicles are involved in anterograde transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110014", "l": "negative regulation of aggregation involved in sorocarp development", "d": ["Any process that decreases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.06379513530257", "identifiers": [{"i": "GO:0071988", "l": "protein localization to spindle pole body", "d": ["A process in which a protein is transported to, or maintained at, the spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0050927", "l": "positive regulation of positive chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061454", "l": "release of sequestered calcium ion into cytosol by Golgi", "d": ["The directed movement of calcium ions (Ca2+) out of the Golgi apparatus into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002370", "l": "natural killer cell cytokine production", "d": ["Any process that contributes to cytokine production by a natural killer cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006058", "l": "mannoprotein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a mannoprotein, a protein that contains covalently bound mannose residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010322", "l": "regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071969", "l": "fungal-type cell wall (1->3)-beta-D-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905306", "l": "positive regulation of cardiac myofibril assembly", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072118", "l": "pronephros structural organization", "d": ["The process that contributes to the act of creating the structural organization of the pronephros. This process pertains to the physical shaping of a rudimentary structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0033628", "l": "regulation of cell adhesion mediated by integrin", "d": ["Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990277", "l": "parasexual reproduction with cellular fusion", "d": ["A type of reproduction in which new individuals are produced from two individuals, with the fusion of two somatic cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1901064", "l": "syringal lignin metabolic process", "d": ["The chemical reactions and pathways involving syringal lignin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060765", "l": "regulation of androgen receptor signaling pathway", "d": ["Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0014874", "l": "response to stimulus involved in regulation of muscle adaptation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0071451", "l": "cellular response to superoxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140779", "l": "XCL1 production", "d": ["The appearance of XCL1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014853", "l": "regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction", "d": ["Any process, involved in skeletal muscle contraction, that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP). Excitatory postsynaptic potential (EPSP) is a temporay increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045864", "l": "positive regulation of pteridine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pteridine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090334", "l": "regulation of cell wall (1->3)-beta-D-glucan biosynthetic process", "d": ["Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043441", "l": "acetoacetic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.646043506621545", "identifiers": [{"i": "GO:0002683", "l": "negative regulation of immune system process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018966", "l": "styrene metabolic process", "d": ["The chemical reactions and pathways involving styrene, an aromatic hydrocarbon liquid soluble in ether and alcohol. When heated, exposed to light or added to a peroxide catalyst, it undergoes polymerization to form polystyrene, a versatile material used in the manufacture of plastics, synthetic rubber, thermal insulation, and packaging. Styrene is a classified mutagen and a suspected carcinogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006239", "l": "dCMP salvage", "d": ["Any process that generates dCMP, deoxycytidine monophosphate from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003312", "l": "pancreatic PP cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071279", "l": "cellular response to cobalt ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903902", "l": "positive regulation of viral life cycle", "d": ["Any process that activates or increases the frequency, rate or extent of viral life cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0009220", "l": "pyrimidine ribonucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032911", "l": "negative regulation of transforming growth factor beta1 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0050832", "l": "defense response to fungus", "d": ["Reactions triggered in response to the presence of a fungus that act to protect the cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034642", "l": "mitochondrion migration along actin filament", "d": ["The directed movement of a mitochondrion along a microfilament, mediated by motor proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.722653756574275", "identifiers": [{"i": "GO:0021675", "l": "nerve development", "d": ["The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0120192", "l": "tight junction assembly", "d": ["A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002881", "l": "negative regulation of chronic inflammatory response to non-antigenic stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071325", "l": "cellular response to mannitol stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046712", "l": "GDP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of GDP, guanosine 5'-diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060058", "l": "positive regulation of apoptotic process involved in mammary gland involution", "d": ["Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process of mammary epithelial cells during mammary gland involution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900891", "l": "negative regulation of pentadecane metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0002888", "l": "positive regulation of myeloid leukocyte mediated immunity", "d": ["Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045929", "l": "positive regulation of juvenile hormone metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0010570", "l": "regulation of filamentous growth", "d": ["Any process that modulates the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150018", "l": "basal dendrite development", "d": ["The process whose specific outcome is the progression of a basal dendrite over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.920281330257616", "identifiers": [{"i": "GO:0042060", "l": "wound healing", "d": ["The series of events that restore integrity to a damaged tissue, following an injury."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046199", "l": "cresol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901005", "l": "ubiquinone-6 catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ubiquinone-6."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106089", "l": "negative regulation of cell adhesion involved in sprouting angiogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905569", "l": "negative regulation of ferrichrome biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ferrichrome biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021934", "l": "hindbrain tangential cell migration", "d": ["The migration of a cell in the hindbrain in which cells move orthogonal to the direction of radial migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044860", "l": "protein localization to plasma membrane raft", "d": ["A process in which a protein is transported to, or maintained in, a location within a plasma membrane raft."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046533", "l": "negative regulation of photoreceptor cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904329", "l": "negative regulation of myofibroblast contraction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905308", "l": "cellular response to miconazole", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904231", "l": "positive regulation of succinate dehydrogenase activity", "d": ["Any process that activates or increases the frequency, rate or extent of succinate dehydrogenase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904528", "l": "positive regulation of microtubule binding", "d": ["Any process that activates or increases the frequency, rate or extent of microtubule binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021523", "l": "somatic motor neuron differentiation", "d": ["The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001502", "l": "cartilage condensation", "d": ["The condensation of mesenchymal cells that have been committed to differentiate into chondrocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062097", "l": "chemosynthesis", "d": ["The cellular metabolic process in which organic chemical compounds are synthesized from carbon-containing molecules and nutrients using energy obtained from the oxidation of inorganic compounds or methane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032753", "l": "positive regulation of interleukin-4 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-4 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044485", "l": "envenomation resulting in fibrinogenolysis in another organism", "d": ["The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinogenolysis, a process that degrades fibrinogen at a variety of Arg-Lys bonds, thus impairing fibrinogen clotting in the bloodstream of the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035131", "l": "post-embryonic pelvic fin morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048941", "l": "posterior lateral line nerve glial cell development", "d": ["The process aimed at the progression of a glial cell in the posterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0050955", "l": "thermoception", "d": ["The series of events required for an organism to receive a temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. Thermoception in larger animals is mainly done in the skin; mammals have at least two types of sensor, for detecting heat (temperatures above body temperature) and cold (temperatures below body temperature)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0030989", "l": "dynein-driven meiotic oscillatory nuclear movement", "d": ["Oscillatory movement of the nucleus involved in meiosis I. This oscillatory movement is led by an astral microtubule array emanating from the spindle pole body, and driven by the microtubule motor cytoplasmic dynein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904297", "l": "positive regulation of osmolarity-sensing cation channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of osmolarity-sensing cation channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:0044359", "l": "modulation of molecular function in another organism", "d": ["The process in which an organism effects a change in the function of proteins in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.576969997299727", "identifiers": [{"i": "GO:0006767", "l": "water-soluble vitamin metabolic process", "d": ["The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021508", "l": "floor plate formation", "d": ["The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019231", "l": "perception of static position", "d": ["The perception of the orientation of different parts of the body with respect to one another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075270", "l": "negative regulation of aecium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007539", "l": "primary sex determination, soma", "d": ["The transmission of information about sexual status from the initial, general, determination to signals specific to the soma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000542", "l": "negative regulation of gastrulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045606", "l": "positive regulation of epidermal cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060628", "l": "regulation of ER to Golgi vesicle-mediated transport", "d": ["Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043931", "l": "ossification involved in bone maturation", "d": ["The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051000", "l": "positive regulation of nitric-oxide synthase activity", "d": ["Any process that activates or increases the activity of the enzyme nitric-oxide synthase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035975", "l": "carbamoyl phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030311", "l": "poly-N-acetyllactosamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0006677", "l": "glycosylceramide metabolic process", "d": ["The chemical reactions and pathways involving glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0030653", "l": "beta-lactam antibiotic metabolic process", "d": ["The chemical reactions and pathways involving a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044808", "l": "oncostatin M production", "d": ["The appearance of oncostatin M due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0042461", "l": "photoreceptor cell development", "d": ["Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002132", "l": "wobble position uridine ribose methylation", "d": ["The process in which the ribose of uridine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.403899653192809", "identifiers": [{"i": "GO:0072690", "l": "single-celled organism vegetative growth phase", "d": ["A phase of population growth during which single celled organisms reproduce by budding, fission, or other asexual methods."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000299", "l": "negative regulation of Rho-dependent protein serine/threonine kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0010431", "l": "seed maturation", "d": ["A process in seed development that occurs after embryogenesis by which a quiescent state is established in a seed. Seed maturation is characterized by storage compound accumulation, acquisition of desiccation tolerance, growth arrest and the entry into a dormancy period of variable length that is broken upon germination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140917", "l": "zinc ion import into mitochondrion", "d": ["The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048695", "l": "negative regulation of collateral sprouting of injured axon", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an injured axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002414", "l": "immunoglobulin transcytosis in epithelial cells", "d": ["The process of transporting immunoglobulin, via transcytosis, from one side of an epithelial cell to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.858070317788027", "identifiers": [{"i": "GO:1901374", "l": "acetate ester transport", "d": ["The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072133", "l": "metanephric mesenchyme morphogenesis", "d": ["The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071581", "l": "regulation of zinc ion transmembrane import", "d": ["Any process that modulates the frequency, rate or extent of zinc ion import."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046114", "l": "guanosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of guanine, guanine riboside, a nucleoside with a wide species distribution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0031060", "l": "regulation of histone methylation", "d": ["Any process that modulates the frequency, rate or extent of the covalent addition of methyl groups to histones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150117", "l": "positive regulation of cell-substrate junction organization", "d": ["Any process that activates or increases the frequency, rate or extent of cell-substrate junction organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:1902099", "l": "regulation of metaphase/anaphase transition of cell cycle", "d": ["Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035053", "l": "dorsal vessel heart proper cell fate commitment", "d": ["The commitment of dorsal vessel cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031651", "l": "negative regulation of heat generation", "d": ["Any process that stops, prevents, or reduces the rate or extent of heat generation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044814", "l": "glycolytic fermentation via PFL pathway", "d": ["The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, followed by pyruvate:formate lyase (PFL) activity. This pathway is found in facultative anaerobes such as E. coli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009047", "l": "dosage compensation by hyperactivation of X chromosome", "d": ["Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060888", "l": "limb epidermis stratification", "d": ["The pattern specification process that results in the subdivision of the epidermis of the limb in space to define a volume in which specific patterns of basal cell, spinous cell and granular cells will differentiate giving rise to the layers of the limb epidermis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0071697", "l": "ectodermal placode morphogenesis", "d": ["The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902525", "l": "regulation of protein monoubiquitination", "d": ["Any process that modulates the frequency, rate or extent of protein monoubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048867", "l": "stem cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a stem cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002436", "l": "immune complex clearance by monocytes and macrophages", "d": ["The process of immune complex clearance by monocytes or macrophages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033526", "l": "tetrapyrrole biosynthetic process from glutamate", "d": ["The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including L-glutamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051391", "l": "tRNA acetylation", "d": ["The modification of tRNA structure by addition of an acetyl group to tRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0055078", "l": "sodium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002480", "l": "antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002496", "l": "proteolysis associated with antigen processing and presentation", "d": ["The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015799", "l": "propanediol transport", "d": ["The directed movement of propanediol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0051385", "l": "response to mineralocorticoid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070104", "l": "negative regulation of interleukin-6-mediated signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of an interleukin-6-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904873", "l": "negative regulation of telomerase RNA localization to Cajal body", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA localization to Cajal body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000408", "l": "negative regulation of T cell extravasation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T cell extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990451", "l": "cellular stress response to acidic pH", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in the homeostasis of organismal or cellular pH (with pH < 7). pH is a measure of the acidity or basicity of an aqueous solution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036530", "l": "protein deglycation, methylglyoxal removal", "d": ["The removal of methylglyoxal from a glycated protein, to form lactate and a deglycated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072082", "l": "specification of proximal tubule identity", "d": ["The process in which the proximal tubule of the kidney nephron acquires its identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075280", "l": "regulation of uredinium development", "d": ["Any process that modulates the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097714", "l": "response to viscosity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0046348", "l": "amino sugar catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any amino sugar, sugars containing an amino group in place of a hydroxyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044821", "l": "meiotic telomere tethering at nuclear periphery", "d": ["The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904323", "l": "regulation of inhibitory G protein-coupled receptor phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:0070091", "l": "glucagon secretion", "d": ["The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060739", "l": "mesenchymal-epithelial cell signaling involved in prostate gland development", "d": ["Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010205", "l": "photoinhibition", "d": ["The mechanism by which high light intensity inhibits photosynthesis through inactivation of the D1 protein of photosystem II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032194", "l": "ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate", "d": ["The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 3,4-dihydroxy-5-polyprenylbenzoate and 3-methoxy-4-hydroxy-5-polyprenylbenzoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1904092", "l": "regulation of autophagic cell death", "d": ["Any process that modulates the frequency, rate or extent of autophagic cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0051955", "l": "regulation of amino acid transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030947", "l": "regulation of vascular endothelial growth factor receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019668", "l": "anaerobic catabolism of pairs of amino acids", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids; in these reactions, one amino acid is oxidised (acts as an electron donor) and a different amino acid is reduced (acts as an electron acceptor); oxidation of the electron-donating amino acid yields energy in the form of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001200", "l": "positive regulation of dendritic cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060164", "l": "regulation of timing of neuron differentiation", "d": ["The process controlling the activation and/or rate at which a relatively unspecialized cell acquires features of a neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0001767", "l": "establishment of lymphocyte polarity", "d": ["The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0001951", "l": "intestinal D-glucose absorption", "d": ["Uptake of D-glucose into the blood by absorption from the small intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902553", "l": "positive regulation of catalase activity", "d": ["Any process that activates or increases the frequency, rate or extent of catalase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.977148804244202", "identifiers": [{"i": "GO:0030217", "l": "T cell differentiation", "d": ["The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0030326", "l": "embryonic limb morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0043586", "l": "tongue development", "d": ["The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003298", "l": "physiological muscle hypertrophy", "d": ["The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097043", "l": "histone H3-K56 acetylation", "d": ["The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 56 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901822", "l": "delta-carotene metabolic process", "d": ["The chemical reactions and pathways involving delta-carotene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000746", "l": "regulation of defecation rhythm", "d": ["Any process that modulates the frequency, rate or extent of defecation rhythm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061308", "l": "cardiac neural crest cell development involved in heart development", "d": ["The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900156", "l": "positive regulation of bone trabecula formation", "d": ["Any process that activates or increases the frequency, rate or extent of bone trabecula formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902391", "l": "positive regulation of N-terminal peptidyl-serine acetylation", "d": ["Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-serine acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035356", "l": "intracellular triglyceride homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of triglyceride within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0046222", "l": "aflatoxin metabolic process", "d": ["The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.06379513530257", "identifiers": [{"i": "GO:0046365", "l": "monosaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1990497", "l": "regulation of cytoplasmic translation in response to stress", "d": ["Modulation of the frequency, rate or extent of cytoplasmic translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036167", "l": "phenotypic switching in response to host", "d": ["A reversible switch of a cell from one phenotype to another that occurs upon infection of a host or host cell. For example, Candida albicans switches from a unicellular form to an invasive multicellular filamentous form upon infection of host tissue. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.000891501185137", "identifiers": [{"i": "GO:0052200", "l": "response to host defenses", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990547", "l": "mitochondrial phosphate ion transmembrane transport", "d": ["The process in which a phosphate ion is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090616", "l": "mitochondrial mRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of an mRNA molecule that derives from the mitochondrial genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098583", "l": "learned vocalization behavior", "d": ["A vocalization behavior that is the result of learning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018247", "l": "protein-phosphoribosyl dephospho-coenzyme A linkage", "d": ["The linkage of phosphoribosyl dephospho-coenzyme A to protein via peptidyl-serine, to form O-(phosphoribosyl dephospho-coenzyme A)-L-serine; it is uncertain whether the phosphoribosyl glycosidic attachment to the dephospho-coenzyme A is alpha or beta, and through the 2' or the 3' position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0042363", "l": "fat-soluble vitamin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060777", "l": "compound leaf morphogenesis", "d": ["The leaf morphogenesis process that results in the shaping of a compound leaf. A compound leaf is a leaf having two or more distinct leaflets that are evident as such from early in development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060781", "l": "mesenchymal cell proliferation involved in prostate gland development", "d": ["The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075029", "l": "formation of appressorium germ tube hook structure", "d": ["The development of a swollen tip at the growing end of a symbiont spore which usually flattens against the host cell surface prior to appressorium formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0071480", "l": "cellular response to gamma radiation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0015805", "l": "S-adenosyl-L-methionine transport", "d": ["The directed movement of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019488", "l": "ribitol catabolic process to xylulose 5-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of ribitol to form xylulose 5-phosphate. Ribitol is initially converted to D-ribulose, which is phosphorylated to form ribulose 5-phosphate, which is then converted into xylulose 5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901492", "l": "positive regulation of lymphangiogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of lymphangiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0001542", "l": "ovulation from ovarian follicle", "d": ["The process leading to the rupture of the follicle, releasing the centrally located oocyte into the oviduct. An example of this is found in Mus musculus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000350", "l": "positive regulation of CD40 signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of signaling via the CD40 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030388", "l": "fructose 1,6-bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071377", "l": "cellular response to glucagon stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.366262559334615", "identifiers": [{"i": "GO:0002833", "l": "positive regulation of response to biotic stimulus", "d": ["Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061707", "l": "extracellular exosome macropinocytosis", "d": ["The single-organism macropinocytosis process that results in the uptake of an extracellular exosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0018231", "l": "peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine", "d": ["The modification of peptidyl-cysteine to form peptidyl-S-diacylglycerol-L-cysteine; the oleate and palmitate actually represent mixtures of saturated (generally at 3') and unsaturated (generally at 2') fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000238", "l": "zygotene", "d": ["The cell cycle phase which follows leptotene during prophase I of meiosis, and during which each chromosome pairs with its homolog; the two become aligned and crossing over may occur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046036", "l": "CTP metabolic process", "d": ["The chemical reactions and pathways involving CTP, cytidine triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903614", "l": "negative regulation of protein tyrosine phosphatase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein tyrosine phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055020", "l": "positive regulation of cardiac muscle fiber development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0099624", "l": "atrial cardiac muscle cell membrane repolarization", "d": ["The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0000729", "l": "DNA double-strand break processing", "d": ["The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072513", "l": "positive regulation of secondary heart field cardioblast proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001240", "l": "negative regulation of extrinsic apoptotic signaling pathway in absence of ligand", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042489", "l": "negative regulation of odontogenesis of dentin-containing tooth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0032908", "l": "regulation of transforming growth factor beta1 production", "d": ["Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0051580", "l": "regulation of neurotransmitter uptake", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042675", "l": "compound eye cone cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a compound eye cone cell, a cone-shaped cell, that focuses light in a compound eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.314153691348963", "identifiers": [{"i": "GO:0051252", "l": "regulation of RNA metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904309", "l": "response to cordycepin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035729", "l": "cellular response to hepatocyte growth factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903568", "l": "negative regulation of protein localization to ciliary membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002572", "l": "pro-T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021621", "l": "hypoglossal nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the hypoglossal nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0120064", "l": "stomach pylorus smooth muscle contraction", "d": ["A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the most distal part of the stomach."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046305", "l": "alkanesulfonate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.717289085529984", "identifiers": [{"i": "GO:0000902", "l": "cell morphogenesis", "d": ["The developmental process in which the size or shape of a cell is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090163", "l": "establishment of epithelial cell planar polarity", "d": ["The specification and formation of the polarity of an epithelial cell along the plane of the epithelial tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0180015", "l": "nucleoside import across plasma membrane", "d": ["The directed movement of nucleoside from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048643", "l": "positive regulation of skeletal muscle tissue development", "d": ["Any process that activates, maintains or increases the rate of skeletal muscle tissue development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070346", "l": "positive regulation of fat cell proliferation", "d": ["Any process that activates or increases the rate or extent of fat cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009752", "l": "detection of salicylic acid stimulus", "d": ["The series of events in which a salicylic acid stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072708", "l": "response to sorbitol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032540", "l": "positive regulation of host-seeking behavior", "d": ["Any process that activates or increases the frequency, rate or extent of any behavior associated with finding a host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035507", "l": "regulation of myosin-light-chain-phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of myosin-light-chain-phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2000425", "l": "regulation of apoptotic cell clearance", "d": ["Any process that modulates the frequency, rate or extent of apoptotic cell clearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141059", "l": "disruption of host antimicrobial peptide activity", "d": ["Any process in which a symbiont interferes with a host antimicrobial peptide, for example by cleavage or degredation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0009555", "l": "pollen development", "d": ["The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042667", "l": "auditory receptor cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0007160", "l": "cell-matrix adhesion", "d": ["The binding of a cell to the extracellular matrix via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046223", "l": "aflatoxin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0016115", "l": "terpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015970", "l": "guanosine tetraphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0016078", "l": "tRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048349", "l": "regulation of paraxial mesodermal cell fate specification", "d": ["Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048826", "l": "cotyledon morphogenesis", "d": ["The process in which the anatomical structures of the cotyledon are generated and organized. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019416", "l": "polythionate oxidation", "d": ["The chemical reactions and pathways resulting in the conversion of thiosulfate to tetrathionate, using cytochrome c as an electron acceptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.651716354923636", "identifiers": [{"i": "GO:0050920", "l": "regulation of chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901763", "l": "oxytetracycline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of oxytetracycline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902298", "l": "cell cycle DNA replication maintenance of fidelity", "d": ["Any maintenance of fidelity that is involved in cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.50708964941672", "identifiers": [{"i": "GO:0015698", "l": "inorganic anion transport", "d": ["The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901449", "l": "negative regulation of response to butan-1-ol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to butan-1-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905191", "l": "positive regulation of metaphase/anaphase transition of meiosis II", "d": ["Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904653", "l": "regulation of lung alveolus development", "d": ["Any process that modulates the frequency, rate or extent of lung alveolus development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019436", "l": "sophorosyloxydocosanoate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0042775", "l": "mitochondrial ATP synthesis coupled electron transport", "d": ["The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane or chloroplast thylakoid membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904354", "l": "negative regulation of telomere capping", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomere capping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071870", "l": "cellular response to catecholamine stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097202", "l": "activation of cysteine-type endopeptidase activity", "d": ["Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990577", "l": "C-terminal protein demethylation", "d": ["The removal of a methyl group from the C-terminal amino acid of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042785", "l": "evasion of host immune response via modulation of host cytokine network", "d": ["Any mechanism of active immune avoidance which works by regulating host cytokine networks, e.g. by secreting proteins that mimic cytokine receptors that act to sequester host cytokines and inhibit action. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098694", "l": "regulation of synaptic vesicle budding from presynaptic endocytic zone membrane", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle budding from presynaptic endocytic zone membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000386", "l": "positive regulation of ovarian follicle development", "d": ["Any process that activates or increases the frequency, rate or extent of ovarian follicle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072255", "l": "metanephric glomerular mesangial cell development", "d": ["The process whose specific outcome is the progression of a glomerular mesangial cell in the metanephros over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031427", "l": "response to methotrexate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060250", "l": "germ-line stem-cell niche homeostasis", "d": ["A homeostatic process involved in the maintenance of an internal steady state within the germ-line stem-cell niche. This includes control of cellular proliferation and death and control of metabolic function that allows the niche to continue to function. A gem-line stem-cell niche is an anatomical structure that regulates how germ-line stem-cells are used and saves them from depletion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001757", "l": "somite specification", "d": ["The process in which individual somites establish identity during embryogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003186", "l": "tricuspid valve morphogenesis", "d": ["The process in which the structure of the tricuspid valve is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010667", "l": "negative regulation of cardiac muscle cell apoptotic process", "d": ["Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0023058", "l": "adaptation of signaling pathway", "d": ["The regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019332", "l": "aerobic respiration, using nitrite as electron donor", "d": ["The oxidation of nitrite (NO2) to nitrate (NO3), using oxygen (O2) as the electron acceptor. Nitrite oxidation is the final step in nitrification, the oxidation of ammonia to nitrate, and nitrite oxidoreductase (NOR) is the key enzyme complex that catalyzes the conversion of nitrite to nitrate in nitrite oxidizing species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032618", "l": "interleukin-15 production", "d": ["The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044869", "l": "negative regulation by host of viral exo-alpha-sialidase activity", "d": ["The process in which a host organism decreases viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062096", "l": "kinetochore disassembly", "d": ["The disaggregation of a kinetochore into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019672", "l": "ethanol-acetate fermentation to butyrate and caproate", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of ethanol and acetate to butyrate and caproate, yielding energy in the form of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048618", "l": "post-embryonic foregut morphogenesis", "d": ["The process in which the anatomical structures of the foregut are generated and organized, during the post-embryonic phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900805", "l": "brevianamide F biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of brevianamide F. Brevianamide F is the biosynthetic precursor of a large family of biologically active prenylated tryptophan-proline 2,5-diketopiperazines that are produced by some fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0015947", "l": "methane metabolic process", "d": ["The chemical reactions and pathways involving methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001278", "l": "positive regulation of leucine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of leucine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061252", "l": "mesonephric glomerular epithelial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0140420", "l": "heme import into cell", "d": ["The directed movement of a heme from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075324", "l": "negative regulation of oomycete sporangium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003364", "l": "lamellipodium assembly involved in mesendodermal cell migration", "d": ["Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self-propelled movement of a mesendodermal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0060438", "l": "trachea development", "d": ["The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903296", "l": "positive regulation of glutamate secretion, neurotransmission", "d": ["Any process that activates or increases the frequency, rate or extent of glutamate secretion, where glutamate acts as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010375", "l": "stomatal complex patterning", "d": ["The regionalization process of establishing the non-random spatial arrangement of stomatal complex on the surface of a leaf. The stomatal complex is the stomatal guard cells and their associated epidermal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018008", "l": "N-terminal peptidyl-glycine N-myristoylation", "d": ["The myristoylation of the N-terminal glycine of proteins to form the derivative N-myristoyl-glycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098597", "l": "observational learning", "d": ["Learning that occurs through observing the behavior of others."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072157", "l": "epithelial cell migration involved in distal tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to distal tubule morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901434", "l": "regulation of toluene catabolic process", "d": ["Any process that modulates the frequency, rate or extent of toluene catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900004", "l": "negative regulation of serine-type endopeptidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of serine-type endopeptidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000730", "l": "regulation of termination of RNA polymerase I transcription", "d": ["Any process that modulates the frequency, rate or extent of termination of RNA polymerase I transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000296", "l": "spermine transport", "d": ["The directed movement of spermine, N,N-bis(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to spermidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0060740", "l": "prostate gland epithelium morphogenesis", "d": ["The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904191", "l": "positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in meiotic nuclear division", "d": ["Any positive regulation of cyclin-dependent protein serine/threonine kinase activity that is involved in meiotic nuclear division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035002", "l": "liquid clearance, open tracheal system", "d": ["The clearance of liquid from the epithelial tubes of an open tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900281", "l": "positive regulation of CD4-positive, alpha-beta T cell costimulation", "d": ["Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001212", "l": "regulation of vasculogenesis", "d": ["Any process that modulates the frequency, rate or extent of vasculogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002394", "l": "tolerance induction in gut-associated lymphoid tissue", "d": ["Tolerance induction taking place in the gut-associated lymphoid tissue (GALT)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006102", "l": "isocitrate metabolic process", "d": ["The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0048507", "l": "meristem development", "d": ["The process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990550", "l": "mitochondrial alpha-ketoglutarate transmembrane transport", "d": ["The process in which alpha-ketoglutarate is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006574", "l": "valine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of valine, 2-amino-3-methylbutanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045326", "l": "protein-DNA covalent cross-linking via the 3'-end to peptidyl-tyrosine", "d": ["The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-3'-DNA)-L-tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060237", "l": "regulation of fungal-type cell wall organization", "d": ["Any process that modulates the rate, frequency or extent of the formation, arrangement of constituent parts, or disassembly of the fungal-type cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905150", "l": "regulation of voltage-gated sodium channel activity", "d": ["Any process that modulates the frequency, rate or extent of voltage-gated sodium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097230", "l": "cell motility in response to potassium ion", "d": ["Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a potassium ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009963", "l": "positive regulation of flavonoid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006782", "l": "protoporphyrinogen IX biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0021544", "l": "subpallium development", "d": ["The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030394", "l": "fructoseglycine metabolic process", "d": ["The chemical reactions and pathways involving fructoseglycine, a fructose molecule containing a glycine group in place of a hydroxyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021805", "l": "cell movement involved in somal translocation", "d": ["The movement of a cell body from the ventricular zone to the pial surface with a concomitant shortening of the process that extends to the pial surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900321", "l": "regulation of maltotetraose transport", "d": ["Any process that modulates the frequency, rate or extent of maltotetraose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048804", "l": "imaginal disc-derived female genitalia morphogenesis", "d": ["The process in which the anatomical structures of female genitalia are generated and organized from the genital disc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904808", "l": "positive regulation of protein oxidation", "d": ["Any process that activates or increases the frequency, rate or extent of protein oxidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0002662", "l": "negative regulation of B cell tolerance induction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900767", "l": "fonsecin metabolic process", "d": ["The chemical reactions and pathways involving fonsecin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0150147", "l": "cell-cell junction disassembly", "d": ["The disaggregation of a cell-cell junction into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006210", "l": "thymine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039703", "l": "RNA replication", "d": ["The cellular metabolic process in which a cell duplicates one or more molecules of RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010649", "l": "regulation of cell communication by electrical coupling", "d": ["Any process that modulates the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905173", "l": "eukaryotic translation initiation factor 2B complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2B complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "44.103294000707528", "identifiers": [{"i": "GO:0002376", "l": "immune system process", "d": ["Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000091", "l": "mitotic anaphase A", "d": ["The cell cycle phase during which the kinetochore microtubules shorten as chromosomes move toward the spindle poles as part of mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000953", "l": "branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanoate, 2-methylbutanoate, or 2-methylpropanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0043408", "l": "regulation of MAPK cascade", "d": ["Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098921", "l": "retrograde trans-synaptic signaling by endocannabinoid", "d": ["Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an endocannabinoid ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.527781272052167", "identifiers": [{"i": "GO:0051567", "l": "histone H3-K9 methylation", "d": ["The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072706", "l": "response to sodium dodecyl sulfate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060671", "l": "epithelial cell differentiation involved in embryonic placenta development", "d": ["The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990253", "l": "cellular response to leucine starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034240", "l": "negative regulation of macrophage fusion", "d": ["Any process that stops, prevents, or decreases the frequency, rate or extent of macrophage fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900015", "l": "regulation of cytokine production involved in inflammatory response", "d": ["Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1990169", "l": "stress response to copper ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a copper ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051281", "l": "positive regulation of release of sequestered calcium ion into cytosol", "d": ["Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018012", "l": "N-terminal peptidyl-alanine trimethylation", "d": ["The trimethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N,N,N-trimethyl-L-alanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002593", "l": "negative regulation of antigen processing and presentation via MHC class Ib", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072121", "l": "head kidney maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the head kidney to attain its fully functional state. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0042053", "l": "regulation of dopamine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002382", "l": "regulation of tissue kallikrein-kinin cascade", "d": ["Any process that modulates the frequency, rate, or extent of the tissue kallikrein-kinin cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:2000514", "l": "regulation of CD4-positive, alpha-beta T cell activation", "d": ["Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.155424086811493", "identifiers": [{"i": "GO:0075259", "l": "spore-bearing structure development", "d": ["The process whose specific outcome is the progression of a spore-bearing structure over time, from its formation to the mature structure. A spore-bearing structure is an anatomical structure that produces new spores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0015675", "l": "nickel cation transport", "d": ["The directed movement of nickel (Ni) cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046040", "l": "IMP metabolic process", "d": ["The chemical reactions and pathways involving IMP, inosine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990054", "l": "response to temozolomide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temozolomide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035817", "l": "renal sodium ion absorption involved in negative regulation of renal sodium excretion", "d": ["Any process where sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron, which contributes to decreasing the amount of sodium that is excreted in urine per unit time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075137", "l": "response to host redox environment", "d": ["Any process that results in a change in state or activity of the symbiont organism or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the redox environment in host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043134", "l": "regulation of hindgut contraction", "d": ["Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033506", "l": "glucosinolate biosynthetic process from homomethionine", "d": ["The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including homomethionine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052373", "l": "suppression of symbiont entry into host", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent to which it enters into a second organism, where the two organisms are in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031171", "l": "ferricrocin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904344", "l": "regulation of gastric mucosal blood circulation", "d": ["Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019548", "l": "arginine catabolic process to spermine", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including spermine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009227", "l": "nucleotide-sugar catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019991", "l": "septate junction assembly", "d": ["The assembly of a septate junction, an intercellular junction found in invertebrate epithelia that is characterized by a ladder like appearance in electron micrographs and thought to provide structural strength and to provide a barrier to diffusion of solutes through the intercellular space."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903643", "l": "positive regulation of recombination hotspot binding", "d": ["Any process that activates or increases the frequency, rate or extent of recombination hotspot binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0060536", "l": "cartilage morphogenesis", "d": ["The process in which the anatomical structures of cartilage are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072034", "l": "renal vesicle induction", "d": ["Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the renal vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021789", "l": "branchiomotor neuron axon guidance in branchial arch mesenchyme", "d": ["The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043059", "l": "regulation of forward locomotion", "d": ["Any process that modulates the speed, mechanical force, or rhythm of the anterior movement of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902697", "l": "valine catabolic process to isobutanol", "d": ["The chemical reactions and pathways resulting in the breakdown of valine to isobutanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0055093", "l": "response to hyperoxia", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901032", "l": "negative regulation of response to reactive oxygen species", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030841", "l": "positive regulation of intermediate filament polymerization", "d": ["Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006723", "l": "cuticle hydrocarbon biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hydrocarbons that make up the cuticle, the outer layer of some animals and plants, which acts to prevent water loss."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900679", "l": "negative regulation of ferricrocin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ferricrocin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061971", "l": "replacement bone morphogenesis", "d": ["The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090358", "l": "positive regulation of tryptophan metabolic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905833", "l": "negative regulation of microtubule nucleation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035126", "l": "post-embryonic genitalia morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the genitalia are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000165", "l": "regulation of planar cell polarity pathway involved in pericardium morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0009083", "l": "branched-chain amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070185", "l": "mitochondrial valyl-tRNA aminoacylation", "d": ["The process of coupling valine to valyl-tRNA in a mitochondrion, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043103", "l": "hypoxanthine salvage", "d": ["Any process that generates hypoxanthine, 6-hydroxy purine, from derivatives of it without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901712", "l": "positive regulation of homoserine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of homoserine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009090", "l": "homoserine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of homoserine, alpha-amino-gamma-hydroxybutyric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033618", "l": "plasma membrane respiratory chain complex IV assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075229", "l": "negative regulation of encysted zoospore germination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of encysted zoospore germination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045033", "l": "peroxisome inheritance", "d": ["The acquisition of peroxisomes by daughter cells from the mother cell after replication. In Saccharomyces cerevisiae, the number of peroxisomes cells is fairly constant; a subset of the organelles are targeted and segregated to the bud in a highly ordered, vectorial process. Efficient segregation of peroxisomes from mother to bud is dependent on the actin cytoskeleton, and active movement of peroxisomes along actin filaments is driven by the class V myosin motor protein, Myo2p."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010101", "l": "post-embryonic root morphogenesis", "d": ["The process in which the anatomical structures of the post-embryonic root are generated and organized. The post-embryonic root is the root formed after the embryonic phase has been completed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0043550", "l": "regulation of lipid kinase activity", "d": ["Any process that modulates the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110024", "l": "positive regulation of cardiac muscle myoblast proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0042744", "l": "hydrogen peroxide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904160", "l": "protein localization to chloroplast starch grain", "d": ["A process in which a protein is transported to, or maintained in, a location within a chloroplast starch grain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006616", "l": "SRP-dependent cotranslational protein targeting to membrane, translocation", "d": ["The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. The growing chain is never exposed to the cytosol and does not fold until it reaches the ER lumen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0044787", "l": "bacterial-type DNA replication", "d": ["The DNA-dependent DNA replication, exemplified by prokaryotes, that occurs as part of the cell cycle. Prokaryotic DNA replication is bi-directional and originates at a single origin of replication on the circular genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046704", "l": "CDP metabolic process", "d": ["The chemical reactions and pathways involving CDP, cytidine (5'-)diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071335", "l": "hair follicle cell proliferation", "d": ["The multiplication or reproduction of hair follicle cells, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:1905331", "l": "negative regulation of morphogenesis of an epithelium", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060931", "l": "sinoatrial node cell development", "d": ["The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0030422", "l": "siRNA processing", "d": ["A process leading to the generation of a functional small interfering RNA (siRNA). Includes the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides. May also include amplification of the siRNA by RNA-directed RNA polymerase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903617", "l": "positive regulation of mitotic cytokinesis, division site positioning", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis, division site positioning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903797", "l": "positive regulation of inorganic anion transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of inorganic anion transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006589", "l": "octopamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021547", "l": "midbrain-hindbrain boundary initiation", "d": ["The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905324", "l": "telomere-telomerase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a telomere-telomerase complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071233", "l": "cellular response to leucine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009589", "l": "detection of UV", "d": ["The series of events in which an ultraviolet radiation (UV light) stimulus is received and converted into a molecular signal. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010142", "l": "farnesyl diphosphate biosynthetic process, mevalonate pathway", "d": ["The pathway that converts acetate, in the form of acetyl-CoA, to farnesyl diphosphate (FPP) through a series of mevalonate intermediates. Farnesyl diphosphate is an important substrate for other essential pathways, such as biosynthesis of sterols."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.468223660644441", "identifiers": [{"i": "GO:0014051", "l": "gamma-aminobutyric acid secretion", "d": ["The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1990505", "l": "mitotic DNA replication maintenance of fidelity", "d": ["Any maintenance of fidelity that is involved in mitotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071672", "l": "negative regulation of smooth muscle cell chemotaxis", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097248", "l": "maintenance of protein location in cell cortex of cell tip", "d": ["A process in which a protein or protein complex is maintained in a specific location in the cell cortex of a cell tip, and is prevented from moving elsewhere. The cell cortex of a cell tip is the region directly beneath the plasma membrane at either end of the longest axis of a cylindrical or elongated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0003157", "l": "endocardium development", "d": ["The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0042430", "l": "indole-containing compound metabolic process", "d": ["The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045782", "l": "positive regulation of cell budding", "d": ["Any process that activates or increases the frequency, rate or extent of cell budding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099110", "l": "microtubule polymerization based protein transport to cell tip cortex", "d": ["The transport of a protein to the cortex of the cell tip, driven by polymerization of a microtubule to which the protein is attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0015920", "l": "lipopolysaccharide transport", "d": ["The directed movement of lipopolysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904379", "l": "protein localization to cytosolic proteasome complex involved in ERAD pathway", "d": ["Any protein localization to cytosolic proteasome complex that is involved in ERAD pathway. Following their retrotranslocation out of the endoplasmic reticulum, protein substrates must be shuttled to the cytosolic proteasome for degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900352", "l": "negative regulation of methanofuran biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0003017", "l": "lymph circulation", "d": ["The flow of lymph through the body of an animal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900333", "l": "regulation of methane biosynthetic process from 3-(methylthio)propionic acid", "d": ["Any process that modulates the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030494", "l": "bacteriochlorophyll biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002373", "l": "plasmacytoid dendritic cell cytokine production", "d": ["Any process that contributes to cytokine production by a plasmacytoid dendritic cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140734", "l": "ammonium excretion", "d": ["The elimination of ammonium ions from an excretory cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061480", "l": "response to asparaginase", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an asparaginase stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0031055", "l": "chromatin remodeling at centromere", "d": ["Dynamic structural changes in centromeric DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007639", "l": "homeostasis of number of meristem cells", "d": ["Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the meristem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901252", "l": "regulation of intracellular transport of viral material", "d": ["Any process that modulates the frequency, rate or extent of egress of virus within host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160018", "l": "positive regulation of platelet rolling", "d": ["Any process that increases the rate, frequency, or extent of platelet rolling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070535", "l": "histone H2A K63-linked ubiquitination", "d": ["A histone ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a lysine residue in histone H2A or the variant H2AX."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043290", "l": "apocarotenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019860", "l": "uracil metabolic process", "d": ["The chemical reactions and pathways involving uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1904889", "l": "regulation of excitatory synapse assembly", "d": ["Any process that modulates the frequency, rate or extent of excitatory synapse assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901175", "l": "lycopene metabolic process", "d": ["The chemical reactions and pathways involving lycopene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016360", "l": "sensory organ precursor cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a sensory organ precursor cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1904037", "l": "positive regulation of epithelial cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061942", "l": "negative regulation of c-di-GMP signaling", "d": ["Any process that decreases the rate, frequency or extent of c-di-GMP signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007458", "l": "progression of morphogenetic furrow involved in compound eye morphogenesis", "d": ["The morphogenetic furrow is a dorsoventral indentation which sweeps anteriorly across the eye disc. Ommatidia begin to form along the furrow, resulting in a graded series of ommatidial development across the anterior/posterior axis of the disc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905459", "l": "regulation of vascular associated smooth muscle cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0046813", "l": "receptor-mediated virion attachment to host cell", "d": ["The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061872", "l": "hepatic stellate cell contraction", "d": ["The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a hepatic stellate cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0036168", "l": "filamentous growth of a population of unicellular organisms in response to heat", "d": ["The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to an increase in temperature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046067", "l": "dGDP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903882", "l": "negative regulation of interleukin-17-mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010697", "l": "negative regulation of mitotic spindle pole body separation", "d": ["Any process that decreases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071044", "l": "histone mRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090181", "l": "regulation of cholesterol metabolic process", "d": ["Any process that modulates the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046597", "l": "negative regulation of viral entry into host cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the entry of viral entry into a host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042333", "l": "chemotaxis to oxidizable substrate", "d": ["The directed movement of a motile cell or organism in response to the presence of an oxidizable substrate, for example, fructose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019485", "l": "beta-alanine catabolic process to L-alanine", "d": ["The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including L-alanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002464", "l": "peripheral tolerance induction to nonself antigen", "d": ["Tolerance induction to nonself antigens in the periphery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000040", "l": "regulation of planar cell polarity pathway involved in axis elongation", "d": ["Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in axis elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902084", "l": "fumagillin metabolic process", "d": ["The chemical reactions and pathways involving fumagillin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035310", "l": "notum cell fate specification", "d": ["The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a notum cell, if left in its normal environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061847", "l": "response to cholecystokinin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.927964040871231", "identifiers": [{"i": "GO:0062014", "l": "negative regulation of small molecule metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901595", "l": "response to hesperadin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.282738951573606", "identifiers": [{"i": "GO:0060560", "l": "developmental growth involved in morphogenesis", "d": ["The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035701", "l": "hematopoietic stem cell migration", "d": ["The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.783030043623796", "identifiers": [{"i": "GO:0048545", "l": "response to steroid hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0140056", "l": "organelle localization by membrane tethering", "d": ["The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120207", "l": "endocytosis, site selection", "d": ["The process of selecting and or marking the position where endocytosis will occur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001149", "l": "negative regulation of dipeptide transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003294", "l": "atrial ventricular junction remodeling", "d": ["The reorganization or renovation of heart tissue that contributes to the maturation of the connection between an atrium and a ventricle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072707", "l": "cellular response to sodium dodecyl sulfate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900916", "l": "positive regulation of octadecene biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of octadecene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018868", "l": "2-aminobenzenesulfonate metabolic process", "d": ["The chemical reactions and pathways involving 2-aminobenzenesulfonate, aniline-o-sulfonic acid, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0097154", "l": "GABAergic neuron differentiation", "d": ["The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000065", "l": "negative regulation of cortisol biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cortisol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002101", "l": "tRNA wobble cytosine modification", "d": ["The process in which a cytosine in position 34 of a tRNA is post-transcriptionally modified."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045476", "l": "nurse cell apoptotic process", "d": ["Any apoptotic process in a nurse cell. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.468544520863134", "identifiers": [{"i": "GO:0006775", "l": "fat-soluble vitamin metabolic process", "d": ["The chemical reactions and pathways involving of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901161", "l": "primary amino compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of primary amino compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106233", "l": "glycosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a glycosome, a membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043561", "l": "regulation of translational initiation in response to osmotic stress", "d": ["Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030491", "l": "heteroduplex formation", "d": ["The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903071", "l": "positive regulation of ER-associated ubiquitin-dependent protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006738", "l": "nicotinamide riboside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046159", "l": "ocellus pigment catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0090628", "l": "plant epidermal cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a plant epidermal cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032916", "l": "positive regulation of transforming growth factor beta3 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:1904103", "l": "regulation of convergent extension involved in gastrulation", "d": ["Any process that modulates the frequency, rate or extent of convergent extension involved in gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036171", "l": "filamentous growth of a population of unicellular organisms in response to chemical stimulus", "d": ["The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a chemical stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032525", "l": "somite rostral/caudal axis specification", "d": ["The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010104", "l": "regulation of ethylene-activated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of ethylene (ethene) signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060967", "l": "negative regulation of gene silencing by regulatory ncRNA", "d": ["Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048849", "l": "neurohypophysis formation", "d": ["The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036516", "l": "chemoattraction of dopaminergic neuron axon", "d": ["The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:2000177", "l": "regulation of neural precursor cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of neural precursor cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0032274", "l": "gonadotropin secretion", "d": ["The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070830", "l": "bicellular tight junction assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060155", "l": "platelet dense granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet dense granule. A platelet dense granule is an electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120059", "l": "negative regulation of small intestinal transit", "d": ["Any process that decreases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901106", "l": "tetracenomycin C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tetracenomycin C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051624", "l": "inhibition of norepinephrine uptake", "d": ["Any process that prevents the activation of the directed movement of norepinephrine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021619", "l": "hypoglossal nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.411753859901495", "identifiers": [{"i": "GO:0034330", "l": "cell junction organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0000002", "l": "mitochondrial genome maintenance", "d": ["The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.824513090543306", "identifiers": [{"i": "GO:0021537", "l": "telencephalon development", "d": ["The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045855", "l": "negative regulation of pole plasm oskar mRNA localization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003293", "l": "heart valve cell differentiation", "d": ["The process in which an endocardial cushion cell give rise to a cell that is part of a heart valve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0042206", "l": "halogenated hydrocarbon catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of halogenated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with halogen atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0070783", "l": "growth of unicellular organism as a thread of attached cells", "d": ["A filamentous growth process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium such as an agar plate, exhibited by unicellular fungi under certain growth conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901552", "l": "positive regulation of endothelial cell development", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial cell development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009625", "l": "response to insect", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002206", "l": "gene conversion of immunoglobulin genes", "d": ["The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032603", "l": "fractalkine production", "d": ["The appearance of fractalkine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097615", "l": "modulation by host of symbiont type IV pilus-dependent motility", "d": ["The process in which an organism effects a change in the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903278", "l": "positive regulation of sodium ion export across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of sodium ion export across the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.781964347917338", "identifiers": [{"i": "GO:0007005", "l": "mitochondrion organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0070198", "l": "protein localization to chromosome, telomeric region", "d": ["Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0034032", "l": "purine nucleoside bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043932", "l": "ossification involved in bone remodeling", "d": ["The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002127", "l": "tRNA wobble base cytosine methylation", "d": ["The process in which the base of cytosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the C5 position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060763", "l": "mammary duct terminal end bud growth", "d": ["The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904937", "l": "sensory neuron migration", "d": ["The orderly movement of a sensory neuron from one site to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036103", "l": "Kdo2-lipid A metabolic process", "d": ["The chemical reactions and pathways involving Kdo2-lipid A, a lipopolysaccharide (LPS) component."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904712", "l": "positive regulation of Wnt-Frizzled-LRP5/6 complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061356", "l": "regulation of Wnt protein secretion", "d": ["Any process that modulates the frequency, rate or extent of the controlled release of a Wnt protein from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000476", "l": "maturation of 4.5S rRNA", "d": ["Any process involved in the maturation of a precursor 4.5S ribosomal RNA (rRNA) molecule into a mature 4.5S rRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000437", "l": "carbon catabolite repression of transcription from RNA polymerase II promoter", "d": ["A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043145", "l": "sno(s)RNA 3'-end cleavage", "d": ["The endonucleolytic cleavage of snoRNA 3' ends, which is required for mature snoRNAs to be functional."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018876", "l": "benzonitrile metabolic process", "d": ["The chemical reactions and pathways involving benzonitrile. Benzonitrile is used as a solvent and chemical intermediate in the pharmaceutical, dyestuffs and rubber industries. It is highly toxic and harmful in contact with skin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.465174152298118", "identifiers": [{"i": "GO:0033363", "l": "secretory granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060065", "l": "uterus development", "d": ["The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0015994", "l": "chlorophyll metabolic process", "d": ["The chemical reactions and pathways involving chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904903", "l": "ESCRT III complex disassembly", "d": ["The disaggregation of an ESCRT III complex into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000512", "l": "lncRNA-mediated post-transcriptional gene silencing", "d": ["A post-transcriptional gene silencing pathway in which regulatory long noncoding RNAs (lncRNAs) elicit silencing of specific target genes, often miRNAs or mRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032688", "l": "negative regulation of interferon-beta production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901119", "l": "tobramycin metabolic process", "d": ["The chemical reactions and pathways involving tobramycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0030682", "l": "mitigation of host defenses by symbiont", "d": ["A process by which an organism avoids or tolerates the effects of its host organism's defense response. The host defense response is mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0090185", "l": "negative regulation of kidney development", "d": ["Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0043967", "l": "histone H4 acetylation", "d": ["The modification of histone H4 by the addition of an acetyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003399", "l": "cytoneme morphogenesis", "d": ["The process in which the anatomical structures of a cytoneme are shaped. A cytoneme is a long, thin and polarized actin-based cytoplasmic extension that projects from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902558", "l": "5'-adenylyl sulfate transmembrane transport", "d": ["The process in which 5'-adenylyl sulfate is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032772", "l": "negative regulation of tyrosinase activity", "d": ["Any process that stops or reduces the activity of a tyrosinase enzyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050938", "l": "regulation of xanthophore differentiation", "d": ["Any process that modulates the frequency, rate or extent of xanthophore differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901774", "l": "lincomycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lincomycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903782", "l": "regulation of sodium ion import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of sodium ion import across the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019267", "l": "asparagine biosynthetic process from cysteine", "d": ["The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0034085", "l": "establishment of sister chromatid cohesion", "d": ["The process in which the sister chromatids of a replicated chromosome become associated with each other during S phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150062", "l": "complement-mediated synapse pruning", "d": ["Synaptic pruning mediated by complement system signalling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034761", "l": "positive regulation of iron ion transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006297", "l": "nucleotide-excision repair, DNA gap filling", "d": ["Repair of the gap in the DNA helix by DNA polymerase and DNA ligase after the portion of the strand containing the lesion has been removed by pyrimidine-dimer repair enzymes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.116918913335823", "identifiers": [{"i": "GO:0043500", "l": "muscle adaptation", "d": ["A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0021603", "l": "cranial nerve formation", "d": ["The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904045", "l": "cellular response to aldosterone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903431", "l": "positive regulation of cell maturation", "d": ["Any process that activates or increases the frequency, rate or extent of cell maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052472", "l": "modulation by host of symbiont transcription", "d": ["Any process in which an organism modulates the frequency, rate or extent of its symbiont's transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0033143", "l": "regulation of intracellular steroid hormone receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.98780181426379", "identifiers": [{"i": "GO:0051146", "l": "striated muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1905216", "l": "positive regulation of RNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of RNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905234", "l": "cellular response to codeine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902406", "l": "mitotic actomyosin contractile ring maintenance", "d": ["Any actomyosin contractile ring maintenance that is involved in mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075300", "l": "negative regulation of zygospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0006547", "l": "histidine metabolic process", "d": ["The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070536", "l": "protein K63-linked deubiquitination", "d": ["A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061275", "l": "mesonephric proximal tubule development", "d": ["The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014716", "l": "skeletal muscle satellite stem cell asymmetric division involved in skeletal muscle regeneration", "d": ["Skeletal muscle satellite cell asymmetric division that occurs during a process in which damaged muscle tissue is being rebuilt."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902351", "l": "response to imidacloprid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an imidacloprid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904157", "l": "DN4 thymocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a DN4 thymocyte. A DN4 thymocyte is a CD4-,CD8- thymocyte that is also CD44-,CD25-."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090223", "l": "chromatin-templated microtubule nucleation", "d": ["The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from chromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0015011", "l": "nickel-tetrapyrrole coenzyme metabolic process", "d": ["The chemical reactions and pathways involving an enzyme cofactor consisting of a tetrapyrrole structure containing nickel, such as the F-430 cofactor found in methyl-coenzyme M reductase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0035418", "l": "protein localization to synapse", "d": ["Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072145", "l": "proximal convoluted tubule segment 1 cell development", "d": ["The process whose specific outcome is the progression of an S1 cell in the kidney over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060399", "l": "positive regulation of growth hormone receptor signaling pathway", "d": ["Any process that increases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000488", "l": "positive regulation of brassinosteroid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of brassinosteroid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990743", "l": "protein sialylation", "d": ["A protein modification process that results in the addition of a sialic acid unit to the end of an oligosaccharide chain in a glycoprotein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048388", "l": "endosomal lumen acidification", "d": ["Any process that reduces the pH of the endosomal lumen, measured by the concentration of the hydrogen ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140462", "l": "pericentric heterochromatin organization", "d": ["The organization of chromatin into heterochromatin at the pericentric region of a chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140429", "l": "positive regulation of mitotic sister chromatid biorientation", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid biorientation, the mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0080052", "l": "response to histidine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990213", "l": "negative regulation by symbiont of salicylic acid levels in host", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of salicylic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0071421", "l": "manganese ion transmembrane transport", "d": ["A process in which a manganese ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901558", "l": "response to metformin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metformin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902214", "l": "regulation of interleukin-4-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of interleukin-4-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.310554257082671", "identifiers": [{"i": "GO:1901615", "l": "organic hydroxy compound metabolic process", "d": ["The chemical reactions and pathways involving organic hydroxy compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032755", "l": "positive regulation of interleukin-6 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-6 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.444551060876734", "identifiers": [{"i": "GO:0016567", "l": "protein ubiquitination", "d": ["The process in which one or more ubiquitin groups are added to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904909", "l": "positive regulation of maintenance of mitotic sister chromatid cohesion, telomeric", "d": ["Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0007618", "l": "mating", "d": ["The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033373", "l": "maintenance of protease location in mast cell secretory granule", "d": ["A process in which a protease is maintained in a secretory granule in a mast cell and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0043173", "l": "nucleotide salvage", "d": ["Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety, from derivatives of it without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903377", "l": "negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001984", "l": "artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure", "d": ["An increase in the internal diameter of an artery, triggered by vasomotor suppression, during the chemoreceptor response to decreased blood pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.77580605496118", "identifiers": [{"i": "GO:0010876", "l": "lipid localization", "d": ["Any process in which a lipid is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901795", "l": "3-(3-hydroxyphenyl)propanoate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 3-(3-hydroxyphenyl)propanoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061613", "l": "glycolytic process from glycerol", "d": ["The glycolytic process in which glycerol is catabolized to pyruvate generating ATP and NADH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0007637", "l": "proboscis extension reflex", "d": ["The extension, through direct muscle actions, of the proboscis (the trunk-like extension of the mouthparts on the adult external head) in response to a nutritional stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.06379513530257", "identifiers": [{"i": "GO:0002775", "l": "antimicrobial peptide production", "d": ["The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0010560", "l": "positive regulation of glycoprotein biosynthetic process", "d": ["Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070107", "l": "regulation of interleukin-27-mediated signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of an interleukin-27-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048760", "l": "plant parenchymal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a parenchymal cell. Parenchymal cells are the most abundant and versatile cells in plants. They have very few distinguishing characteristics and botanists classify them as any cell type that cannot be assigned to any other structural or functional class. They can redifferentiate and dedifferentiate and are involved in storage, basic metabolism and other processes. The cells are polyhedral, typically with thin, non-lignified cellulose cell walls and nucleate living protoplasm. They vary in size, form, and wall structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009248", "l": "K antigen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0019634", "l": "organic phosphonate metabolic process", "d": ["The chemical reactions and pathways involving phosphonates, any organic compounds containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Metabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000587", "l": "negative regulation of platelet-derived growth factor receptor-beta signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902665", "l": "response to isobutanol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isobutanol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0001840", "l": "neural plate development", "d": ["The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902252", "l": "positive regulation of erythrocyte apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000417", "l": "negative regulation of eosinophil migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060719", "l": "chorionic trophoblast cell development", "d": ["The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097101", "l": "blood vessel endothelial cell fate specification", "d": ["The process involved in the specification of identity of a blood vessel endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. A blood vessel endothelial cell is an endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070504", "l": "selenium-containing prosthetic group biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0099612", "l": "protein localization to axon", "d": ["A process in which a protein is transported to or maintained in a location within an axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009934", "l": "regulation of meristem structural organization", "d": ["Any process that modulates the frequency, rate or extent of meristem organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903276", "l": "regulation of sodium ion export across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of sodium ion export across the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003037", "l": "detection of pH by carotid body chemoreceptor signaling", "d": ["The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in a carotid body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016058", "l": "maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling", "d": ["Maintenance of the excited state of a photoreceptor cell to produce a steady-state current as a result of signals generated by rhodopsin activation by a photon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045057", "l": "cisternal progression", "d": ["The process that results in the physical movement of a new cis-Golgi stack from the cis-position, nearest the endoplasmic reticulum (ER), to the trans position, farthest from the ER, successively becoming first a medial-Golgi cisterna and then a trans-Golgi cisterna."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018428", "l": "copper incorporation into copper-sulfur cluster", "d": ["The incorporation of copper into a copper-sulfur cluster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002352", "l": "B cell negative selection", "d": ["Any process leading to negative selection in B cells. Mechanisms of negative selection include anergy and deletion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051012", "l": "microtubule sliding", "d": ["The movement of one microtubule along another microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048047", "l": "mating behavior, sex discrimination", "d": ["The behavior of individuals for the purpose of discriminating between the sexes, for the purpose of finding a suitable mating partner."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904704", "l": "positive regulation of protein localization to adherens junction", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018402", "l": "protein-chondroitin sulfate linkage via chondroitin sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine", "d": ["Chondroitin sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901811", "l": "beta-carotene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of beta-carotene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.675373588411375", "identifiers": [{"i": "GO:1902969", "l": "mitotic DNA replication", "d": ["Any nuclear DNA replication that is involved in a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021509", "l": "roof plate formation", "d": ["The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044077", "l": "modulation by symbiont of host receptor-mediated endocytosis", "d": ["The process in which a symbiont organism modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903595", "l": "positive regulation of histamine secretion by mast cell", "d": ["Any process that activates or increases the frequency, rate or extent of histamine secretion by mast cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900317", "l": "positive regulation of maltopentaose transport", "d": ["Any process that activates or increases the frequency, rate or extent of maltopentaose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0034505", "l": "tooth mineralization", "d": ["The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001166", "l": "regulation of histone H2B ubiquitination", "d": ["Any process that modulates the frequency, rate or extent of histone H2B ubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1903430", "l": "negative regulation of cell maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000384", "l": "negative regulation of ectoderm development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071573", "l": "shelterin complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a shelterin complex. A shelterin complex is a nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901919", "l": "positive regulation of exoribonuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of exoribonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098906", "l": "regulation of Purkinje myocyte action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:1901334", "l": "lactone metabolic process", "d": ["The chemical reactions and pathways involving lactone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034131", "l": "regulation of toll-like receptor 1 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 1 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0021697", "l": "cerebellar cortex formation", "d": ["The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014738", "l": "regulation of muscle hyperplasia", "d": ["Any process that modulates the frequency, rate or extent of muscle hyperplasia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001695", "l": "histamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014067", "l": "negative regulation of phosphatidylinositol 3-kinase signaling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045579", "l": "positive regulation of B cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of B cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110054", "l": "regulation of actin filament annealing", "d": ["Any process that modulates the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033625", "l": "positive regulation of integrin activation", "d": ["Any process that activates or increases the frequency, rate, or extent of integrin activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000607", "l": "negative regulation of cell proliferation involved in mesonephros development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in mesonephros development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006438", "l": "valyl-tRNA aminoacylation", "d": ["The process of coupling valine to valyl-tRNA, catalyzed by valyl-tRNA synthetase. The valyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a valine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070148", "l": "mitochondrial glutaminyl-tRNA aminoacylation", "d": ["The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903367", "l": "positive regulation of fear response", "d": ["Any process that activates or increases the frequency, rate or extent of fear response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0021510", "l": "spinal cord development", "d": ["The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048574", "l": "long-day photoperiodism, flowering", "d": ["A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light that exceeds the critical day length. The critical day length varies between species. Although the term is long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 minus the critical day length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.693546388589041", "identifiers": [{"i": "GO:0048609", "l": "multicellular organismal reproductive process", "d": ["The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:1903338", "l": "regulation of cell wall organization or biogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell wall organization or biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0009235", "l": "cobalamin metabolic process", "d": ["The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010616", "l": "negative regulation of cardiac muscle adaptation", "d": ["Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0016045", "l": "detection of bacterium", "d": ["The series of events in which a stimulus from a bacterium is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070105", "l": "positive regulation of interleukin-6-mediated signaling pathway", "d": ["Any process that increases the rate, frequency or extent of an interleukin-6-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0005997", "l": "xylulose metabolic process", "d": ["The chemical reactions and pathways involving xylulose, the ketopentose threo-2-pentulose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002128", "l": "tRNA nucleoside ribose methylation", "d": ["The process that results in the modification of the sugar of a nucleoside in tRNA at the 2'O position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0044145", "l": "modulation of formation of structure involved in a symbiotic process", "d": ["Any process that modulates the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032667", "l": "regulation of interleukin-23 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-23 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900799", "l": "cordyol C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cordyol C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090473", "l": "lys-arg specific dibasic protein processing", "d": ["Any protein processing achieved by the cleavage of a peptide bond after a lysine-arginine amino acid residue combination within a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044623", "l": "positive regulation of cell migration in another organism", "d": ["Any process that activates or increases the frequency, rate or extent of cell migration in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0100009", "l": "regulation of fever generation by prostaglandin secretion", "d": ["Any prostaglandin secretion process that regulates fever generation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010936", "l": "negative regulation of macrophage cytokine production", "d": ["Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043923", "l": "positive regulation by host of viral transcription", "d": ["Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043315", "l": "positive regulation of neutrophil degranulation", "d": ["Any process that activates or increases the frequency, rate or extent of neutrophil degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072052", "l": "juxtaglomerulus cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the kidney as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072136", "l": "metanephric mesenchymal cell proliferation involved in metanephros development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a metanephric mesenchymal cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.284222931418633", "identifiers": [{"i": "GO:0055086", "l": "nucleobase-containing small molecule metabolic process", "d": ["The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042354", "l": "L-fucose metabolic process", "d": ["The chemical reactions and pathways involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in fucans, a class of polysaccharides in seaweeds, especially Fucus species, and in the cell wall matrix of higher plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904556", "l": "L-tryptophan transmembrane transport", "d": ["The directed movement of L-tryptophan across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901967", "l": "negative regulation of cellular response to iron ion starvation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to iron ion starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034095", "l": "negative regulation of maintenance of meiotic sister chromatid cohesion", "d": ["Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905130", "l": "carcinine import across plasma membrane", "d": ["The directed movement of carcinine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0046887", "l": "positive regulation of hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048354", "l": "mucilage biosynthetic process involved in seed coat development", "d": ["The chemical reactions and pathways resulting in the formation of mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904003", "l": "negative regulation of sebum secreting cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sebum secreting cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072680", "l": "extracellular matrix-dependent thymocyte migration", "d": ["The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on extracellular matrix components including fibronectin, collagen and laminin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0150195", "l": "transport across blood-cerebrospinal fluid barrier", "d": ["The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-cerebrospinal fluid barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:1904238", "l": "pericyte cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a pericyte cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990637", "l": "response to prolactin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus. The anterior pituitary hormone prolactin has a number of roles including being essential for lactation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903691", "l": "positive regulation of wound healing, spreading of epidermal cells", "d": ["Any process that activates or increases the frequency, rate or extent of wound healing, spreading of epidermal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032293", "l": "non-myelinated axon ensheathment in central nervous system", "d": ["The process in which a non-myelinating glial cell membrane encircles an axon in the central nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035441", "l": "cell migration involved in vasculogenesis", "d": ["The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0021626", "l": "central nervous system maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048566", "l": "embryonic digestive tract development", "d": ["The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030921", "l": "peptidyl-tyrosine dehydrogenation to form (Z)-2,3-didehydrotyrosine", "d": ["The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(Z)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902604", "l": "p-aminobenzoyl-glutamate transmembrane transport", "d": ["The directed movement of N-(4-aminobenzoyl)-L-glutamate across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150089", "l": "multiple spine synapse organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and one or more dendritic spines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0035006", "l": "melanization defense response", "d": ["The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099089", "l": "establishment of endoplasmic reticulum localization to postsynapse", "d": ["The directed movement of endoplasmic reticulum into a postsynaptic compartment such as a dendritic spine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:1990395", "l": "meiotic spindle pole body organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the meiotic spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902663", "l": "negative regulation of peptidyl-L-cysteine S-palmitoylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900902", "l": "regulation of hexadecanal biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of hexadecanal biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.062476272212777", "identifiers": [{"i": "GO:0006022", "l": "aminoglycan metabolic process", "d": ["The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099605", "l": "regulation of action potential firing rate", "d": ["Any process that regulates the frequency of action potentials in a spike train."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072272", "l": "proximal/distal pattern formation involved in metanephric nephron development", "d": ["The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the metanephros. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035799", "l": "ureter maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043104", "l": "positive regulation of GTP cyclohydrolase I activity", "d": ["Any process that activates or increases the activity of the enzyme GTP cyclohydrolase I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009751", "l": "response to salicylic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072225", "l": "metanephric late distal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the metanephric late distal convoluted tubule over time, from its formation to the mature structure. The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085016", "l": "dormancy exit of symbiont in host", "d": ["Exit from dormant state, also known as resuscitation, of the symbiont within the host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0042938", "l": "dipeptide transport", "d": ["The directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009207", "l": "purine ribonucleoside triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021706", "l": "locus ceruleus maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034213", "l": "quinolinate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006041", "l": "glucosamine metabolic process", "d": ["The chemical reactions and pathways involving glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021671", "l": "rhombomere 7 morphogenesis", "d": ["The process in which the anatomical structure of rhombomere 7 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140588", "l": "chromatin looping", "d": ["A chromatin organization process that starts with the loading of an extrusion motor (by an SMC family complex) onto the chromatin, followed by chromatin extrusion that stops at loop anchoring sites on the chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061034", "l": "olfactory bulb mitral cell layer development", "d": ["The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002034", "l": "maintenance of blood vessel diameter homeostasis by renin-angiotensin", "d": ["The process in which the diameter of a blood vessel is changed due to activity of the renin-angiotensin system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141006", "l": "piRNA-mediated retrotransposon silencing by heterochromatin formation", "d": ["A retrotransposon silencing mechanism in which a piRNA triggers heterochromatin assembly. Heterochromatin is a chromatin conformation that is refractory to transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901194", "l": "negative regulation of formation of translation preinitiation complex", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation preinitiation complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0002652", "l": "regulation of tolerance induction dependent upon immune response", "d": ["Any process that modulates the frequency, rate, or extent of tolerance induction dependent upon immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.191040882595608", "identifiers": [{"i": "GO:0009889", "l": "regulation of biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001015", "l": "snoRNA transcription by RNA polymerase II", "d": ["The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002633", "l": "positive regulation of granuloma formation", "d": ["Any process that activates or increases the frequency, rate, or extent of granuloma formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140213", "l": "negative regulation of long-chain fatty acid import into cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of long-chain fatty acid import into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905793", "l": "protein localization to pericentriolar material", "d": ["A process in which a protein is transported to, or maintained in, a location within a pericentriolar material."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048041", "l": "focal adhesion assembly", "d": ["The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060748", "l": "tertiary branching involved in mammary gland duct morphogenesis", "d": ["The branching process in which the mammary gland ducts form tertiary branches off of the secondary branches as part of diestrus and pregnancy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000969", "l": "tRNA exon ligation utilizing ATP as source of linkage phosphate", "d": ["A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous ATP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in vertebrate species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052023", "l": "modulation by symbiont of salicylic acid levels in host", "d": ["The alteration by an organism of the levels of salicylic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903448", "l": "geraniol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of geraniol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990432", "l": "siRNA 3'-end processing", "d": ["The process of forming the mature 3' end of a siRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0000916", "l": "actomyosin contractile ring contraction", "d": ["The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035858", "l": "eosinophil fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into an eosinophil cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010095", "l": "specification of petal identity", "d": ["The process in which a floral organ primordium acquires petal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006423", "l": "cysteinyl-tRNA aminoacylation", "d": ["The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904213", "l": "negative regulation of iodide transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of iodide transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.651613913496419", "identifiers": [{"i": "GO:0001101", "l": "response to acid chemical", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0072025", "l": "distal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090557", "l": "establishment of endothelial intestinal barrier", "d": ["The establishment of a barrier between endothelial cell layers of the intestine to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045615", "l": "positive regulation of plasmatocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of plasmatocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.685364931984026", "identifiers": [{"i": "GO:0003044", "l": "regulation of systemic arterial blood pressure mediated by a chemical signal", "d": ["The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0034587", "l": "piRNA processing", "d": ["A process leading to the generation of a functional piRNA. piRNAs (Piwi-associated RNAs) are a class of 24- to 30-nucleotide RNAs derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072214", "l": "metanephric cortex development", "d": ["The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902812", "l": "regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry", "d": ["Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0140243", "l": "regulation of translation at synapse", "d": ["Any process that regulates translation occurring at the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0032220", "l": "plasma membrane fusion involved in cytogamy", "d": ["The joining of two or more lipid bilayer membranes that surround cells, that contributes to cytogamy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905418", "l": "positive regulation of amoeboid sperm motility", "d": ["Any process that activates or increases the frequency, rate or extent of amoeboid sperm motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035187", "l": "hatching behavior", "d": ["The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070222", "l": "sulfide oxidation, using sulfide dehydrogenase", "d": ["A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide dehydrogenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000009", "l": "negative regulation of protein localization to cell surface", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to the cell surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905309", "l": "positive regulation of cohesin loading", "d": ["Any process that activates or increases the frequency, rate or extent of cohesin loading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035020", "l": "regulation of Rac protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of Rac protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904906", "l": "positive regulation of endothelial cell-matrix adhesion via fibronectin", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018160", "l": "peptidyl-pyrromethane cofactor linkage", "d": ["The covalent binding of a pyrromethane (dipyrrin) cofactor to protein via the sulfur atom of cysteine forming dipyrrolylmethanemethyl-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090345", "l": "cellular organohalogen metabolic process", "d": ["The chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070716", "l": "mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication", "d": ["A mismatch repair process that corrects errors introduced that ensures the accuracy of DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0000086", "l": "G2/M transition of mitotic cell cycle", "d": ["The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901536", "l": "negative regulation of DNA demethylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA demethylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.777964009505382", "identifiers": [{"i": "GO:0072163", "l": "mesonephric epithelium development", "d": ["The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903933", "l": "negative regulation of DNA primase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA primase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010496", "l": "intercellular transport", "d": ["The movement of substances between cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034633", "l": "retinol transport", "d": ["The directed movement of retinol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901872", "l": "ecgonone methyl ester biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ecgonone methyl ester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001207", "l": "regulation of transcription elongation by RNA polymerase I", "d": ["Any process that modulates the frequency, rate or extent of transcription elongation from RNA polymerase I promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036197", "l": "zymosterol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140435", "l": "negative regulation of protein localization to meiotic spindle pole body", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a meiotic spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900362", "l": "positive regulation of pentasaccharide transport", "d": ["Any process that activates or increases the frequency, rate or extent of pentasaccharide transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0061626", "l": "pharyngeal arch artery morphogenesis", "d": ["The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019492", "l": "proline salvage", "d": ["Any process which produces the amino acid proline from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072499", "l": "photoreceptor cell axon guidance", "d": ["The chemotaxis process that directs the migration of a photoreceptor cell axon growth cone to its target in the optic lobe in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003021", "l": "detection of increased carbon dioxide by chemoreceptor signaling", "d": ["The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990864", "l": "response to growth hormone-releasing hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone-releasing hormone stimulus. Growth hormone-releasing hormone regulates the release of growth hormone, as well as some pancreatic proteins, and possibly other proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070426", "l": "positive regulation of nucleotide-binding oligomerization domain containing signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035901", "l": "cellular response to isolation stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045742", "l": "positive regulation of epidermal growth factor receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0018249", "l": "protein dehydration", "d": ["The removal of a water group from a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043097", "l": "pyrimidine nucleoside salvage", "d": ["Any process that generates a pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose, from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035833", "l": "berbamunine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of berbamunine, an isoquinoline alkaloid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0044488", "l": "modulation of voltage-gated sodium channel activity in another organism", "d": ["Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905162", "l": "regulation of phagosome maturation", "d": ["Any process that modulates the frequency, rate or extent of phagosome maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905274", "l": "regulation of modification of postsynaptic actin cytoskeleton", "d": ["Any process that modulates the frequency, rate or extent of modification of postsynaptic actin cytoskeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000745", "l": "nuclear migration involved in conjugation with mutual genetic exchange", "d": ["The net movement of nuclei towards one another, leading to the bilateral transfer of genetic material in organisms undergoing conjugation without cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120197", "l": "mucociliary clearance", "d": ["The respiratory system process driven by motile cilia on epithelial cells of the respiratory tract by which mucus and associated inhaled particles and pathogens trapped within it are moved out of the airways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0007553", "l": "regulation of ecdysteroid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019095", "l": "pole plasm mitochondrial rRNA localization", "d": ["Any process in which mitochondrial ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046725", "l": "negative regulation by virus of viral protein levels in host cell", "d": ["Any process where the infecting virus reduces the levels of viral proteins in a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010363", "l": "regulation of plant-type hypersensitive response", "d": ["Any endogenous process that modulates the frequency, rate or extent of the plant hypersensitive response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071545", "l": "inositol phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901387", "l": "positive regulation of voltage-gated calcium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039708", "l": "nuclear capsid assembly", "d": ["The assembly of a virus capsid that occurs in the nucleus. The assembly of large icosahedral shells for herpesviridae and adenoviridae requires structural proteins that act as chaperones for assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045737", "l": "positive regulation of cyclin-dependent protein serine/threonine kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of CDK activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070981", "l": "L-asparagine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001019", "l": "positive regulation of retrograde axon cargo transport", "d": ["Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901945", "l": "miltiradiene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of miltiradiene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009224", "l": "CMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CMP, cytidine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048056", "l": "R3/R4 cell differentiation", "d": ["The process in which relatively unspecialized cells acquire the specialized features of R3 and R4 photoreceptors. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110010", "l": "basolateral protein secretion", "d": ["The controlled release of proteins from a cell at the sides which interface adjacent cells and near the base."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019547", "l": "arginine catabolic process to ornithine", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070483", "l": "detection of hypoxia", "d": ["The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900057", "l": "positive regulation of leaf senescence", "d": ["Any process that activates or increases the frequency, rate or extent of leaf senescence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009193", "l": "pyrimidine ribonucleoside diphosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905866", "l": "positive regulation of Atg1/ULK1 kinase complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of Atg1/ULK1 kinase complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042070", "l": "maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification", "d": ["Maintenance of the oocyte nucleus in a particular position within the cell during the establishment and maintenance of the axes of the oocyte. An example of this process is found In Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0015770", "l": "sucrose transport", "d": ["The directed movement of sucrose into, out of or within a cell, or between cells by means of some agent such as a transporter or pore. Sucrose is the disaccharide fructofuranosyl-glucopyranoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010734", "l": "negative regulation of protein glutathionylation", "d": ["Any process that decreases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:2000379", "l": "positive regulation of reactive oxygen species metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075004", "l": "adhesion of symbiont spore to host", "d": ["The attachment of a spore of the symbiont to its host via adhesion molecules, general stickiness etc. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0030101", "l": "natural killer cell activation", "d": ["The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018081", "l": "peptide cross-linking via lanthionine or 3-methyl-lanthionine", "d": ["The synthesis of (2R,6R)-lanthionine, sn-(2S,6R)-lanthionine or (2S,3S,6R)-3-methyl-lanthionine, forming an intra-polypeptide cross-link between peptidyl-cysteine, and peptidyl-serine or peptidyl-threonine; dehydration of the serine or threonine residue to the alpha,beta-unsaturated amino acid is the first step; a bond then forms between the ethylene (ethene) group thus formed and the sulfur atom of a cysteine, with the inversion of the configuration of the alpha carbon of the serine or threonine occurring during the process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902164", "l": "positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "d": ["Any process that activates or increases the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0052548", "l": "regulation of endopeptidase activity", "d": ["Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000735", "l": "removal of nonhomologous ends", "d": ["The removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046869", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide", "d": ["The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001003", "l": "regulation of pectin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of pectin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901742", "l": "2-deoxystreptamine metabolic process", "d": ["The chemical reactions and pathways involving 2-deoxystreptamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043132", "l": "NAD transport", "d": ["The directed movement of nicotinamide adenine dinucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; transport may be of either the oxidized form, NAD, or the reduced form, NADH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901490", "l": "regulation of lymphangiogenesis", "d": ["Any process that modulates the frequency, rate or extent of lymphangiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046220", "l": "pyridine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903423", "l": "positive regulation of synaptic vesicle recycling", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle recycling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055047", "l": "generative cell mitosis", "d": ["The process in which the generative cell divides by mitosis to form two haploid cells. These will subsequently differentiate into sperm cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0007638", "l": "mechanosensory behavior", "d": ["Behavior that is dependent upon the sensation of a mechanical stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0032371", "l": "regulation of sterol transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000722", "l": "regulation of cardiac vascular smooth muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.693529410615042", "identifiers": [{"i": "GO:0010035", "l": "response to inorganic substance", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "50.005659893067133", "identifiers": [{"i": "GO:0036211", "l": "protein modification process", "d": ["The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000053", "l": "regulation of Wnt signaling pathway involved in dorsal/ventral axis specification", "d": ["Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051587", "l": "inhibition of dopamine uptake involved in synaptic transmission", "d": ["Any process that prevents the activation of the directed movement of dopamine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140532", "l": "negative regulation of osmosensory signaling MAPK cascade", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling MAPK cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903608", "l": "protein localization to cytoplasmic stress granule", "d": ["A process in which a protein is transported to, or maintained in, a location within a cytoplasmic stress granule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036052", "l": "protein localization to uropod", "d": ["A process in which a protein is transported to, or maintained in, a uropod. A uropod is a membrane projection with related cytoskeletal components at the trailing edge of a migrating cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021661", "l": "rhombomere 4 morphogenesis", "d": ["The process in which the anatomical structure of rhombomere 4 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075039", "l": "establishment of turgor in appressorium", "d": ["The process in which hydrostatic pressure is increased within the symbiont appressorium to breach the cuticle of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0150105", "l": "protein localization to cell-cell junction", "d": ["A process in which a protein is transported to, or maintained, in a location within a cell-cell junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010422", "l": "regulation of brassinosteroid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045754", "l": "positive regulation of acetate catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021755", "l": "eurydendroid cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature eurydendroid cell. Differentiation includes the processes involved in commitment of a neuroblast to a eurydendroid cell fate. A eurydendroid cell is an efferent neuron found in the cerebellar cortex of teleosts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903576", "l": "response to L-arginine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006507", "l": "GPI anchor release", "d": ["The GPI anchor metabolic process that results in enzymatic cleavage of the anchor, releasing an anchored protein from the membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1901185", "l": "negative regulation of ERBB signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ERBB signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048076", "l": "regulation of compound eye pigmentation", "d": ["Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the compound eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0050435", "l": "amyloid-beta metabolic process", "d": ["The chemical reactions and pathways involving amyloid-beta, a glycoprotein associated with Alzheimer's disease, and its precursor, amyloid precursor protein (APP)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0021854", "l": "hypothalamus development", "d": ["The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000400", "l": "positive regulation of thymocyte aggregation", "d": ["Any process that activates or increases the frequency, rate or extent of thymocyte aggregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010043", "l": "response to zinc ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018235", "l": "peptidyl-lysine carboxylation", "d": ["The modification of peptidyl-lysine to form peptidyl-N6-carboxy-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061178", "l": "regulation of insulin secretion involved in cellular response to glucose stimulus", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.155424086811493", "identifiers": [{"i": "GO:1905392", "l": "plant organ morphogenesis", "d": ["The developmental process by which a plant organ is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033538", "l": "ajugose biosynthetic process using galactan:galactan galactosyltransferase", "d": ["The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactan:galactan galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of one raffinose-family oligosaccharide to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0051757", "l": "meiotic sister chromatid separation", "d": ["The process in which sister chromatids are physically detached from each other during meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0044273", "l": "sulfur compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900768", "l": "fonsecin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fonsecin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033381", "l": "establishment of granzyme B localization to T cell secretory granule", "d": ["The directed movement of the protease granzyme B to a location within a secretory granule in a T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090474", "l": "arg-arg specific dibasic protein processing", "d": ["Any protein processing achieved by the cleavage of a peptide bond after two consecutive arginine amino acid residues within a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904631", "l": "response to glucoside", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0048670", "l": "regulation of collateral sprouting", "d": ["Any process that modulates the frequency, rate or extent of collateral sprouting."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061585", "l": "orexin secretion, neurotransmission", "d": ["The controlled release of orexin from a cell in which orexin acts as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002160", "l": "desmosome maintenance", "d": ["The maintenance of a desmosome. A desmosome is a patch-like intercellular junctions found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an interspace of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900036", "l": "positive regulation of cellular response to heat", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to heat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0039678", "l": "viral genome ejection through host cell envelope", "d": ["Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm. Caudovirales carry an ejection apparatus that can be long and contractile, long and noncontractile, or short, and is able to penetrate the host cell envelope to deliver the viral genome into the host cell cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010827", "l": "regulation of glucose transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009721", "l": "detection of auxin stimulus", "d": ["The series of events in which an auxin stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0006026", "l": "aminoglycan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0110088", "l": "hippocampal neuron apoptotic process", "d": ["Any apoptotic process that occurs in a hippocampal neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032819", "l": "positive regulation of natural killer cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.850028330009977", "identifiers": [{"i": "GO:0048565", "l": "digestive tract development", "d": ["The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097080", "l": "plasma membrane selenite transport", "d": ["The directed movement of inorganic selenite (HSeO3-1 at physiological pH) across a plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060772", "l": "leaf phyllotactic patterning", "d": ["The radial pattern formation process that results in the formation of leaf primordia around the center of a shoot apical meristem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0043519", "l": "regulation of myosin II filament organization", "d": ["Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071907", "l": "determination of digestive tract left/right asymmetry", "d": ["Determination of the asymmetric location of various parts of the digestive tract with respect to the left and right halves of the organism. The digestive tract is the anatomical structure through which food passes and is processed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0048483", "l": "autonomic nervous system development", "d": ["The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060123", "l": "regulation of growth hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035848", "l": "oviduct morphogenesis", "d": ["The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070932", "l": "histone H3 deacetylation", "d": ["The modification of histone H3 by the removal of one or more acetyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900311", "l": "positive regulation of maltoheptaose metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of maltoheptaose metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019339", "l": "parathion catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of parathion, a highly toxic organophosphate compound. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901789", "l": "benzoyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of benzoyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904737", "l": "positive regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase", "d": ["Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032017", "l": "positive regulation of Ran protein signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of Ran protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0021549", "l": "cerebellum development", "d": ["The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1990571", "l": "meiotic centromere clustering", "d": ["The process by which centromeres/kinetochores attach to and migrate along microtubules to become localized to clusters at the spindle pole body during a meiotic prometaphase I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900744", "l": "regulation of p38MAPK cascade", "d": ["Any process that modulates the frequency, rate or extent of p38MAPK cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905273", "l": "positive regulation of proton-transporting ATP synthase activity, rotational mechanism", "d": ["Any process that activates or increases the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036138", "l": "peptidyl-histidine hydroxylation", "d": ["The hydroxylation of peptidyl-histidine to form peptidyl-hydroxyhistidine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003326", "l": "pancreatic A cell fate commitment", "d": ["The commitment of a cell to a pancreatic A cell and its capacity to differentiate into a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.095705093080383", "identifiers": [{"i": "GO:0003016", "l": "respiratory system process", "d": ["A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001281", "l": "regulation of muscle cell chemotaxis toward tendon cell", "d": ["Any process that modulates the frequency, rate or extent of muscle cell chemotaxis toward tendon cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.370574996118883", "identifiers": [{"i": "GO:0034762", "l": "regulation of transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1901465", "l": "positive regulation of tetrapyrrole biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0032465", "l": "regulation of cytokinesis", "d": ["Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033341", "l": "regulation of collagen binding", "d": ["Any process that modulates the frequency, rate or extent of collagen binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0140250", "l": "regulation protein catabolic process at synapse", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060791", "l": "sebaceous gland placode formation", "d": ["The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.685364931984026", "identifiers": [{"i": "GO:0034976", "l": "response to endoplasmic reticulum stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903235", "l": "positive regulation of calcium ion-dependent exocytosis of neurotransmitter", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090199", "l": "regulation of release of cytochrome c from mitochondria", "d": ["Any process that modulates the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990570", "l": "GDP-mannose transmembrane transport", "d": ["The process in which GDP-mannose is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050836", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0033875", "l": "ribonucleoside bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0050936", "l": "xanthophore differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a xanthophore cell. Xanthophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or xanthosomes. This makes them yellow to orange in appearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002247", "l": "clearance of damaged tissue involved in inflammatory response wound healing", "d": ["The series of events leading to removal of necrotic debris that contribute to an inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0006584", "l": "catecholamine metabolic process", "d": ["The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0035162", "l": "embryonic hemopoiesis", "d": ["The stages of blood cell formation that take place within the embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035922", "l": "foramen ovale closure", "d": ["The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009398", "l": "FMN biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of FMN, the oxidized form of flavin mononucleotide (riboflavin 5'-(dihydrogen phosphate)), which acts as a coenzyme for a number of oxidative enzymes including NADH dehydrogenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901316", "l": "positive regulation of histone H2A K63-linked ubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of histone H2A K63-linked ubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903027", "l": "regulation of opsonization", "d": ["Any process that modulates the frequency, rate or extent of opsonization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900694", "l": "positive regulation of (+)-kotanin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of (+)-kotanin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903121", "l": "regulation of TRAIL-activated apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060890", "l": "limb spinous cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal spinous cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060819", "l": "inactivation of X chromosome by genomic imprinting", "d": ["Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by genomic imprinting."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900613", "l": "F-9775B catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of F-9775B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0035988", "l": "chondrocyte proliferation", "d": ["The multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0001933", "l": "negative regulation of protein phosphorylation", "d": ["Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.019725967809748", "identifiers": [{"i": "GO:0032103", "l": "positive regulation of response to external stimulus", "d": ["Any process that activates, maintains or increases the rate of a response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:2000300", "l": "regulation of synaptic vesicle exocytosis", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904142", "l": "negative regulation of carotenoid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of carotenoid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0045185", "l": "maintenance of protein location", "d": ["Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002522", "l": "leukocyte migration involved in immune response", "d": ["The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036228", "l": "protein localization to nuclear inner membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within the nuclear inner membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150092", "l": "regulation of synaptic scaling", "d": ["A process that modulates synaptic scaling. Synaptic scaling is a form of synaptic plasticity, which entails uniform adjustments in the strength of all synapses on a cell in response to prolonged changes in the electrical activity of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060570", "l": "negative regulation of peptide hormone processing", "d": ["Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046150", "l": "melanin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001304", "l": "lipoxin B4 metabolic process", "d": ["The chemical reactions and pathways involving lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034551", "l": "mitochondrial respiratory chain complex III assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex (also known as ubiquinol-cytochrome c reductase), in the mitochondrial inner membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032384", "l": "negative regulation of intracellular cholesterol transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051483", "l": "terpenoid biosynthetic process, mevalonate-independent", "d": ["The chemical reactions and pathways resulting in the formation of terpenoids, independent of mevalonate. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-independent biosynthesis, it is produced from pyruvate and glyceraldehyde 3-phosphate via intermediates including 1-deoxy-D-xylulose 5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0046629", "l": "gamma-delta T cell activation", "d": ["The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061977", "l": "hip joint articular cartilage development", "d": ["The process whose specific outcome is the progression of hip joint articular cartilage over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007382", "l": "specification of segmental identity, maxillary segment", "d": ["The specification of the characteristic structures of the maxillary segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904664", "l": "negative regulation of N-terminal peptidyl-methionine acetylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-methionine acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903281", "l": "positive regulation of calcium:sodium antiporter activity", "d": ["Any process that activates or increases the frequency, rate or extent of calcium:sodium antiporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046451", "l": "diaminopimelate metabolic process", "d": ["The chemical reactions and pathways involving diaminopimelate, the anion of the dicarboxylic acid 2,6-diaminoheptanedioic acid. It is an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072252", "l": "metanephric juxtaglomerulus cell development", "d": ["The process whose specific outcome is the progression of a metanephric juxtaglomerulus cell over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036017", "l": "response to erythropoietin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus. Erythropoietin is a glycoprotein hormone that controls erythropoiesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007441", "l": "anterior midgut (ectodermal) morphogenesis", "d": ["The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902250", "l": "regulation of erythrocyte apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006580", "l": "ethanolamine metabolic process", "d": ["The chemical reactions and pathways involving ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990536", "l": "phosphoenolpyruvate transmembrane import into Golgi lumen", "d": ["The directed movement of phosphoenolpyruvate into the Golgi lumen across the Golgi membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0000748", "l": "conjugation with mutual genetic exchange", "d": ["A conjugation process that results in the mutual exchange and union of only genetic information between compatible mating types. Conjugation without cellular fusion requires direct cellular contact between the organisms without plasma membrane fusion. The organisms involved in conjugation without cellular fusion separate after nuclear exchange."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090701", "l": "specification of plant organ identity", "d": ["The regionalization process in which the identity of a plant organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032607", "l": "interferon-alpha production", "d": ["The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072067", "l": "early distal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the early distal convoluted tubule over time, from its formation to the mature structure. The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:1902047", "l": "polyamine transmembrane transport", "d": ["The process in which a polyamine macromolecule is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007304", "l": "chorion-containing eggshell formation", "d": ["The construction of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048450", "l": "floral organ structural organization", "d": ["The process that contributes to the act of creating the structural organization of floral organs. This process pertains to the physical shaping of a rudimentary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.879406879579491", "identifiers": [{"i": "GO:0015772", "l": "oligosaccharide transport", "d": ["The directed movement of oligosaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligosaccharides are molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903336", "l": "negative regulation of vacuolar transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062108", "l": "negative regulation of protein localization to non-growing cell tip", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a non-growing cell tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0010659", "l": "cardiac muscle cell apoptotic process", "d": ["A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090062", "l": "regulation of trehalose metabolic process", "d": ["Any process that modulates the frequency, rate or extent of trehalose metabolism, the chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000842", "l": "positive regulation of dehydroepiandrosterone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of dehydroepiandrosterone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000549", "l": "positive regulation of dendritic cell dendrite assembly", "d": ["Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106111", "l": "regulation of mitotic cohesin ssDNA (lagging strand) loading", "d": ["Any process that modulates the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090518", "l": "L-arginine transmembrane import into vacuole", "d": ["The directed movement of L-arginine into the vacuole across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046093", "l": "deoxycytidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.003741351937961", "identifiers": [{"i": "GO:0034440", "l": "lipid oxidation", "d": ["The removal of one or more electrons from a lipid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045957", "l": "negative regulation of complement activation, alternative pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900185", "l": "positive regulation of xanthone-containing compound biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of xanthone-containing compound biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0062002", "l": "regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity", "d": ["Any process that modulates the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0042823", "l": "pyridoxal phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0011000", "l": "replication fork arrest at mating type locus", "d": ["A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the mating type locus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006648", "l": "dihydrosphingosine-1-P pathway", "d": ["A phosphatidylethanolamine biosynthetic process that proceeds via the enzymatic action of dihydrosphingosine phosphate lyase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902059", "l": "negative regulation of sporocarp development involved in sexual reproduction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sporocarp development involved in sexual reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061229", "l": "mesonephric juxtaglomerulus cell development", "d": ["The process whose specific outcome is the progression of a mesonephric juxtaglomerulus cell over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.290269238295835", "identifiers": [{"i": "GO:0014032", "l": "neural crest cell development", "d": ["The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901198", "l": "positive regulation of calcium ion transport into cytosol involved in cellular response to calcium ion", "d": ["Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to calcium ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048587", "l": "regulation of short-day photoperiodism, flowering", "d": ["Any process that modulates the frequency, rate or extent of short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.569439710577498", "identifiers": [{"i": "GO:0030447", "l": "filamentous growth", "d": ["The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045969", "l": "positive regulation of juvenile hormone biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904183", "l": "negative regulation of pyruvate dehydrogenase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate dehydrogenase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010837", "l": "regulation of keratinocyte proliferation", "d": ["Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.305865553172417", "identifiers": [{"i": "GO:0031326", "l": "regulation of cellular biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009158", "l": "ribonucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031388", "l": "organic acid phosphorylation", "d": ["The process of introducing one or more phosphate groups into an organic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0003032", "l": "detection of oxygen", "d": ["The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048935", "l": "peripheral nervous system neuron development", "d": ["The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0015948", "l": "methanogenesis", "d": ["The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106280", "l": "positive regulation of UDP-N-acetylglucosamine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900020", "l": "positive regulation of protein kinase C activity", "d": ["Any process that activates or increases the frequency, rate or extent of protein kinase C activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0034059", "l": "response to anoxia", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035382", "l": "sterol transmembrane transport", "d": ["The process in which a sterol is transported across a membrane. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905534", "l": "positive regulation of leucine import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of leucine import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030502", "l": "negative regulation of bone mineralization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900897", "l": "negative regulation of heptadecane biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072391", "l": "phenol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phenol, a compound that consists of a benzene ring with one attached hydroxyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070170", "l": "regulation of tooth mineralization", "d": ["Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.664775500092716", "identifiers": [{"i": "GO:0006699", "l": "bile acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035479", "l": "angioblast cell migration from lateral mesoderm to midline", "d": ["The directed movement of angioblasts from the lateral mesoderm to the midline which occurs as part of the formation of the early midline vasculature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.23035275591424", "identifiers": [{"i": "GO:0006909", "l": "phagocytosis", "d": ["A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099158", "l": "regulation of recycling endosome localization within postsynapse", "d": ["Any process that modulates the frequency, rate or extent of transport or maintenance of location of a postsynaptic recycling endosome within the postsynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071911", "l": "synchronous neurotransmitter secretion", "d": ["Release of neurotransmitter at the synapse that lasts for just a few milliseconds after action potential invasion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000984", "l": "negative regulation of ATP citrate synthase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ATP citrate synthase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904671", "l": "negative regulation of cell differentiation involved in stem cell population maintenance", "d": ["Any negative regulation of cell differentiation that is involved in stem cell population maintenance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019227", "l": "neuronal action potential propagation", "d": ["The propagation of an action potential along an axon, away from the soma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097552", "l": "mitochondrial double-strand break repair via homologous recombination", "d": ["The repair of a double-strand break in mitochondrial DNA in which the broken DNA molecule is repaired using homologous sequences."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097287", "l": "7-cyano-7-deazaguanine metabolic process", "d": ["The chemical reactions and pathways involving the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905512", "l": "regulation of short-term synaptic potentiation", "d": ["Any process that modulates the frequency, rate or extent of short-term synaptic potentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904715", "l": "negative regulation of chaperone-mediated autophagy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated autophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032277", "l": "negative regulation of gonadotropin secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070575", "l": "peptide mating pheromone maturation involved in regulation of pheromone-induced unidirectional conjugation", "d": ["The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of pheromone-induced unidirectional conjugation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.652527572959436", "identifiers": [{"i": "GO:0043603", "l": "amide metabolic process", "d": ["The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033217", "l": "regulation of transcription from RNA polymerase II promoter in response to iron ion starvation", "d": ["Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032738", "l": "positive regulation of interleukin-15 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-15 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0009297", "l": "pilus assembly", "d": ["The assembly from its constituent parts of a pilus, a short filamentous structure of bacterial cell, flagella-like in structure and generally present in many copies. Pili are variously involved in transfer of nucleic acids, adherence to surfaces, and formation of pellicles. Is required for bacterial conjugation, or can play a role in adherence to surfaces (when it is called a fimbrium), and in the formation of pellicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.884204812668166", "identifiers": [{"i": "GO:0070085", "l": "glycosylation", "d": ["The covalent attachment and further modification of carbohydrate residues to a substrate molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0051225", "l": "spindle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000294", "l": "nuclear-transcribed mRNA catabolic process, RNase MRP-dependent", "d": ["A minor MRP-dependent nuclear-transcribed mRNA degradation pathway that begins with an endonucleolytic cleavage to generate unprotected ends."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050677", "l": "positive regulation of urothelial cell proliferation", "d": ["Any process that activates or increases the rate or extent of urothelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0061091", "l": "regulation of phospholipid translocation", "d": ["Any process that modulates the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0035787", "l": "cell migration involved in kidney development", "d": ["The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018162", "l": "peptide cross-linking via S-(2-aminovinyl)-3-methyl-D-cysteine", "d": ["The formation of a cross-link between peptidyl-cysteine and peptidyl-threonine via the formation of S-(2-aminovinyl)-3-methyl-D-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0080145", "l": "intracellular cysteine homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of cysteine within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070255", "l": "regulation of mucus secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.789865030533292", "identifiers": [{"i": "GO:0007271", "l": "synaptic transmission, cholinergic", "d": ["The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001009", "l": "regulation of plant-type cell wall cellulose biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0031054", "l": "pre-miRNA processing", "d": ["A process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046985", "l": "positive regulation of hemoglobin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060909", "l": "regulation of DNA replication initiation involved in plasmid copy number maintenance", "d": ["Any process that modulates the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140646", "l": "negative regulation of pre-B cell receptor expression", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the process leading up to expression of the pre-B cell receptor on the surface of pre-B cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098673", "l": "inhibition of host DNA replication by virus", "d": ["Any process by which a virus inhibits DNA replication in its host cell. Some bacteriophages are known to do this, possibly as a way of increasing the pool of nucleotides available for virus replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "28.638793768052317", "identifiers": [{"i": "GO:0007275", "l": "multicellular organism development", "d": ["The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072219", "l": "metanephric cortical collecting duct development", "d": ["The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010582", "l": "floral meristem determinacy", "d": ["The process in which a floral meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006680", "l": "glucosylceramide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021737", "l": "emboliform nucleus development", "d": ["The process whose specific outcome is the progression of the emboliform nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080051", "l": "cutin transport", "d": ["The directed movement of cutin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cutin, which consists of C16-18 fatty acids, is the major component of the cuticle that covers the plant surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046251", "l": "limonene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "46.068626929436171", "identifiers": [{"i": "GO:0006139", "l": "nucleobase-containing compound metabolic process", "d": ["Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018964", "l": "propylene metabolic process", "d": ["The chemical reactions and pathways involving propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining. It is used mainly in the preparation of alkylates for gasoline and in the production of polypropylene, acrylonitrile, propylene oxide and a number of other industrial chemicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061682", "l": "seminal vesicle morphogenesis", "d": ["The process in which the anatomical structures of a seminal vesicle are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021921", "l": "regulation of cell proliferation in dorsal spinal cord", "d": ["The process that modulates the frequency, rate or extent of cell proliferation in the dorsal spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903174", "l": "fatty alcohol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fatty alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098672", "l": "inhibition of host CRISPR-cas system by virus", "d": ["A process by which a virus inhibits the CRISPR-cas system of its host."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000370", "l": "positive regulation of clathrin-dependent endocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0042491", "l": "inner ear auditory receptor cell differentiation", "d": ["The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000878", "l": "positive regulation of oligopeptide transport", "d": ["Any process that activates or increases the frequency, rate or extent of oligopeptide transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900636", "l": "heptadecane biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heptadecane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009178", "l": "pyrimidine deoxyribonucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035436", "l": "triose phosphate transmembrane transport", "d": ["The process in which triose phosphate (glyceraldehyde 3-phosphate) is transported across a membrane. Glyceraldehyde 3-phosphate is any organic three carbon compound phosphate ester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001289", "l": "lipid X metabolic process", "d": ["The chemical reactions and pathways involving lipid X, 2,3-diacylglucosamine 1-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0016090", "l": "prenol metabolic process", "d": ["The chemical reactions and pathways involving prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045708", "l": "regulation of larval salivary gland boundary specification", "d": ["Any process that modulates the frequency, rate or extent of salivary gland determination in a larval organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000267", "l": "negative regulation of blood coagulation, intrinsic pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, intrinsic pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006053", "l": "N-acetylmannosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:2000468", "l": "regulation of peroxidase activity", "d": ["Any process that modulates the frequency, rate or extent of peroxidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0035435", "l": "phosphate ion transmembrane transport", "d": ["The process in which a phosphate is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903387", "l": "positive regulation of homophilic cell adhesion", "d": ["Any process that activates or increases the frequency, rate or extent of homophilic cell adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.9148261867131", "identifiers": [{"i": "GO:0003073", "l": "regulation of systemic arterial blood pressure", "d": ["The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901070", "l": "guanosine-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of guanosine-containing compounds (guanosines)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1905292", "l": "regulation of neural crest cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of neural crest cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0006027", "l": "glycosaminoglycan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000089", "l": "positive regulation of mesonephric glomerulus development", "d": ["Any process that activates or increases the frequency, rate or extent of mesonephric glomerulus development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045700", "l": "regulation of spermatid nuclear differentiation", "d": ["Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0051754", "l": "meiotic sister chromatid cohesion, centromeric", "d": ["The cell cycle process in which centromeres of sister chromatids are joined during meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006045", "l": "N-acetylglucosamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0001839", "l": "neural plate morphogenesis", "d": ["The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990654", "l": "sebum secreting cell proliferation", "d": ["The multiplication or reproduction of sebocytes by cell division, resulting in the expansion of their population. A sebocyte is an epithelial cell that makes up the sebaceous glands, and secrete sebum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060949", "l": "cardiac vascular smooth muscle cell fate commitment", "d": ["The commitment of cells to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0036342", "l": "post-anal tail morphogenesis", "d": ["The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071725", "l": "response to triacyl bacterial lipopeptide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097304", "l": "lipoprotein biosynthetic process via signal peptide cleavage", "d": ["The chemical reactions and pathways by which signal peptide cleavage leads to formation of a water-soluble protein-lipid complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903925", "l": "response to bisphenol A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903026", "l": "negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905243", "l": "cellular response to 3,3',5-triiodo-L-thyronine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061735", "l": "DNM1L-mediated stimulation of mitophagy in response to mitochondrial depolarization", "d": ["A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a DNM1L-family molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0033627", "l": "cell adhesion mediated by integrin", "d": ["The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072728", "l": "response to Gentian violet", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044850", "l": "menstrual cycle", "d": ["A type of ovulation cycle where the endometrium is shed if pregnancy does not occur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901596", "l": "response to reversine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:1901570", "l": "fatty acid derivative biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fatty acid derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904865", "l": "positive regulation of beta-catenin-TCF complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of beta-catenin-TCF complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0060918", "l": "auxin transport", "d": ["The directed movement of auxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Auxins are a group of plant hormones that regulates aspects of plant growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002037", "l": "negative regulation of L-glutamate import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamate import into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009803", "l": "cinnamic acid metabolic process", "d": ["The chemical reactions and pathways involving cinnamic acid, 3-phenyl-2-propenoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0160015", "l": "platelet rolling", "d": ["Transient adhesive interactions between platelets and endothelial cells lining blood vessels. Carbohydrates on circulating platelets bind selectins or other molecules on the vessel wall causing the platelets to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between surface molecules of platelets and endothelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002019", "l": "regulation of renal output by angiotensin", "d": ["The process in which angiotensin directly modulates the rate of urine output by the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032727", "l": "positive regulation of interferon-alpha production", "d": ["Any process that activates or increases the frequency, rate, or extent of interferon-alpha production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0110025", "l": "DNA strand resection involved in replication fork processing", "d": ["The 5' to 3' exonucleolytic resection of DNA at the site of a stalled replication fork that contributes to replication fork processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036448", "l": "cellular response to glucose-phosphate stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of glucose-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0045921", "l": "positive regulation of exocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904536", "l": "regulation of mitotic telomere tethering at nuclear periphery", "d": ["Any process that modulates the frequency, rate or extent of mitotic telomere tethering at nuclear periphery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901537", "l": "positive regulation of DNA demethylation", "d": ["Any process that activates or increases the frequency, rate or extent of DNA demethylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0070303", "l": "negative regulation of stress-activated protein kinase signaling cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0006590", "l": "thyroid hormone generation", "d": ["The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090052", "l": "regulation of pericentric heterochromatin formation", "d": ["Any process that modulates the frequency, rate or extent of heterochromatin formation at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905784", "l": "regulation of anaphase-promoting complex-dependent catabolic process", "d": ["Any process that modulates the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1990918", "l": "double-strand break repair involved in meiotic recombination", "d": ["The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix that contributes to reciprocal meiotic recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006256", "l": "UDP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of UDP, uridine (5'-)diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014875", "l": "detection of muscle activity involved in regulation of muscle adaptation", "d": ["The series of events by which a muscle activity stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070805", "l": "regulation of phialide development", "d": ["Any process that modulates the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080148", "l": "negative regulation of response to water deprivation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a response to water deprivation. Response to water deprivation is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905765", "l": "negative regulation of protection from non-homologous end joining at telomere", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protection from non-homologous end joining at telomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035443", "l": "tripeptide transmembrane transport", "d": ["The directed movement of a tripeptide across a membrane by means of some agent such as a transporter or pore. A tripeptide is a compound containing three amino acids linked together by peptide bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905529", "l": "regulation of uracil import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of uracil import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006668", "l": "sphinganine-1-phosphate metabolic process", "d": ["The chemical reactions and pathways involving sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051618", "l": "positive regulation of histamine uptake", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of histamine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0046959", "l": "habituation", "d": ["A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000634", "l": "regulation of primary miRNA processing", "d": ["Any process that modulates the frequency, rate or extent of primary microRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0045666", "l": "positive regulation of neuron differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036256", "l": "cellular response to methylamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060160", "l": "negative regulation of dopamine receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of dopamine receptor protein signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061212", "l": "mesonephric juxtaglomerular apparatus development", "d": ["The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0008209", "l": "androgen metabolic process", "d": ["The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905808", "l": "positive regulation of synapse pruning", "d": ["Any process that activates or increases the frequency, rate or extent of synapse pruning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900019", "l": "regulation of protein kinase C activity", "d": ["Any process that modulates the frequency, rate or extent of protein kinase C activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018289", "l": "molybdenum incorporation into metallo-sulfur cluster", "d": ["The incorporation of molybdenum into a metallo-sulfur cluster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034183", "l": "negative regulation of maintenance of mitotic sister chromatid cohesion", "d": ["Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070926", "l": "regulation of ATP:ADP antiporter activity", "d": ["Any process that modulates the activity of an ATP:ADP antiporter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1903409", "l": "reactive oxygen species biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018124", "l": "peptide cross-linking via 5'-(N6-L-lysine)-L-topaquinone", "d": ["The cross-linking of the epsilon-amino group of a peptidyl-lysine with peptidyl-topaquinone, a modified tyrosine residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905941", "l": "positive regulation of gonad development", "d": ["Any process that activates or increases the frequency, rate or extent of gonad development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090262", "l": "regulation of transcription-coupled nucleotide-excision repair", "d": ["Any process that modulates the frequency, rate, or extent of the nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052323", "l": "negative regulation of phytoalexin biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1904512", "l": "regulation of initiation of premeiotic DNA replication", "d": ["Any process that modulates the frequency, rate or extent of initiation of premeiotic DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062110", "l": "negative regulation of DNA recombinase disassembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombinase complex disassembly, the disaggregation of a DNA recombinase complex into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048077", "l": "negative regulation of compound eye pigmentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the compound eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900723", "l": "negative regulation of protein adenylylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein adenylylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032721", "l": "negative regulation of lymphotoxin A production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphotoxin A production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903011", "l": "negative regulation of bone development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bone development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902097", "l": "positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium", "d": ["Any positive regulation of transcription from RNA polymerase II promoter that is involved in defense response to Gram-negative bacterium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000056", "l": "ribosomal small subunit export from nucleus", "d": ["The directed movement of a ribosomal small subunit from the nucleus into the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042905", "l": "9-cis-retinoic acid metabolic process", "d": ["The chemical reactions and pathways involving 9-cis-retinoic acid, a metabolically active vitamin A derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901034", "l": "regulation of L-glutamine import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of L-glutamine import into cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021704", "l": "locus ceruleus morphogenesis", "d": ["The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904252", "l": "negative regulation of bile acid metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0008359", "l": "regulation of bicoid mRNA localization", "d": ["Any process that modulates the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060941", "l": "epicardium-derived cardiac fibroblast cell fate commitment", "d": ["The commitment of an epicardial cell to a cardiac fibroblast cell fate and its capacity to differentiate into a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0018282", "l": "metal incorporation into metallo-sulfur cluster", "d": ["The formation of a cluster of several metal atoms, including iron, nickel, molybdenum, vanadium, or copper, with one or more bridging (mu-bond) sulfur atoms; amino acids residues in proteins that may ligate the metal sulfur cluster are cysteine, histidine, aspartate, glutamate, serine and cysteine persulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051865", "l": "protein autoubiquitination", "d": ["The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010918", "l": "positive regulation of mitochondrial membrane potential", "d": ["Any process that activates or increases the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033227", "l": "dsRNA transport", "d": ["The directed movement of dsRNA, double-stranded ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009853", "l": "photorespiration", "d": ["A light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved. The substrate is glycolate formed in large quantities in chloroplasts from 2-phosphoglycolate generated from ribulose 1,5-bisphosphate by the action of ribulose-bisphosphate carboxylase; the glycolate enters the peroxisomes where it is converted by glycolate oxidase to glyoxylate which undergoes transamination to glycine. This then passes into the mitochondria where it is decarboxylated forming one molecule of serine for every two molecules of glycine. This pathway also exists in photosynthetic bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018963", "l": "phthalate metabolic process", "d": ["The chemical reactions and pathways involving phthalate, the anion of phthalic acid. Phthalic acid diesters are used industrially in the production of a variety of household and consumer goods including plastic polymers, lubricating oils, and carriers for perfumes in cosmetics, while phthalic acid itself is used industrially as a plasticizer. Terephthalate is used in the synthesis of polyethylene terephthalate (polyethene terephthlate, abbreviated PET or PETE), a plastic polymer with many commercial uses."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044581", "l": "butyryl-CoA catabolic process to butyrate", "d": ["The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butyrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052785", "l": "cellulose catabolism by endo-processive cellulases", "d": ["The breakdown into simpler components of cellulose. Catabolism is initiated by endohydrolytic attacks on the cellulose chain, and the resulting pieces are further degraded by cellulase enzymes to produce smaller and smaller fragments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0044650", "l": "adhesion of symbiont to host cell", "d": ["The attachment of a symbiont to a host cell via adhesion molecules, general stickiness etc., either directly or indirectly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120215", "l": "positive regulation of histidine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of histidine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:1901678", "l": "iron coordination entity transport", "d": ["The directed movement of an iron coordination entity into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0021583", "l": "pons morphogenesis", "d": ["The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0106056", "l": "regulation of calcineurin-mediated signaling", "d": ["Any process that modulates the frequency, rate or extent of calcineurin-mediated signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018900", "l": "dichloromethane metabolic process", "d": ["The chemical reactions and pathways involving dichloromethane, a dichlorinated derivative of methane. It is a colorless organic liquid with a sweet, chloroform-like odor, often used as a paint remover."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0051592", "l": "response to calcium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990299", "l": "Bub1-Bub3 complex localization to kinetochore", "d": ["A cellular protein complex localization that acts on a Bub1-Bub3 complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0019755", "l": "one-carbon compound transport", "d": ["The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000802", "l": "positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation", "d": ["Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120324", "l": "procyclogenesis", "d": ["The morphological, biochemical and genetic changes that induce the differentiation of bloodstream form trypomastigotes into procyclic trypomastigotes in some of the Trypanosomatidae species such as Trypanosoma brucei. This process occurs inside the midgut of the tsetse fly vectors in T. brucei."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046506", "l": "sulfolipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sulfolipid, a compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904999", "l": "positive regulation of leukocyte adhesion to arterial endothelial cell", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900227", "l": "positive regulation of NLRP3 inflammasome complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of NLRP3 inflammasome complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0090175", "l": "regulation of establishment of planar polarity", "d": ["Any process that modulates the rate, frequency or extent of the establishment of planar polarity, the coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045705", "l": "negative regulation of salivary gland boundary specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0030049", "l": "muscle filament sliding", "d": ["The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.815303035410999", "identifiers": [{"i": "GO:0000280", "l": "nuclear division", "d": ["The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015760", "l": "glucose-6-phosphate transport", "d": ["The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.907960664560427", "identifiers": [{"i": "GO:0034660", "l": "ncRNA metabolic process", "d": ["The chemical reactions and pathways involving non-coding RNA transcripts (ncRNAs)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0071574", "l": "protein localization to medial cortex", "d": ["A process in which a protein is transported to, or maintained in, the medial cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0042475", "l": "odontogenesis of dentin-containing tooth", "d": ["The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007279", "l": "pole cell formation", "d": ["Formation of a small group of cells (pole cells) at the posterior pole of the insect blastula. They are the first cells to cellularize after the arrival of nuclei at the end of the syncytial blastula stage and are the precursors to the insect germ cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010758", "l": "regulation of macrophage chemotaxis", "d": ["Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098911", "l": "regulation of ventricular cardiac muscle cell action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045609", "l": "positive regulation of inner ear auditory receptor cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060140", "l": "modulation by virus of syncytium formation via plasma membrane fusion", "d": ["The formation in a cell that has been targeted by a virus of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.155424086811493", "identifiers": [{"i": "GO:0071216", "l": "cellular response to biotic stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000492", "l": "regulation of interleukin-18-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of interleukin-18-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900720", "l": "negative regulation of uterine smooth muscle relaxation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of uterine smooth muscle relaxation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903960", "l": "negative regulation of anion transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anion transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046249", "l": "alpha-pinene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035046", "l": "pronuclear migration", "d": ["The directed movement of the male and female pronuclei towards each other prior to their fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046214", "l": "enterobactin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019495", "l": "proline catabolic process to 2-oxoglutarate", "d": ["The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including 2-oxoglutarate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018901", "l": "2,4-dichlorophenoxyacetic acid metabolic process", "d": ["The chemical reactions and pathways involving 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000650", "l": "negative regulation of sodium ion transmembrane transporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0061525", "l": "hindgut development", "d": ["The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000734", "l": "negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045628", "l": "regulation of T-helper 2 cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of T-helper 2 cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099185", "l": "postsynaptic intermediate filament cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprised of intermediate filament and their associated proteins in the postsynaptic cytoskeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035340", "l": "inosine transport", "d": ["The directed movement of the purine ribonucleoside inosine, also known as hypoxanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0007297", "l": "follicle cell of egg chamber migration", "d": ["The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905139", "l": "apical ectodermal ridge formation", "d": ["The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901524", "l": "regulation of mitophagy", "d": ["Any process that modulates the frequency, rate or extent of macromitophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046448", "l": "tropane alkaloid metabolic process", "d": ["The chemical reactions and pathways involving tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038056", "l": "negative regulation of BMP signaling pathway by negative regulation of BMP secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway by stopping, preventing or reducing the frequency, rate or extent of secretion of a member of the BMP family of proteins from the signaling cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0098528", "l": "skeletal muscle fiber differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019452", "l": "L-cysteine catabolic process to taurine", "d": ["The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including taurine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0098810", "l": "neurotransmitter reuptake", "d": ["The directed movement of neurotransmitter molecules from the extrasynaptic space into the presynaptic cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061408", "l": "positive regulation of transcription from RNA polymerase II promoter in response to heat stress", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042619", "l": "poly-hydroxybutyrate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0031998", "l": "regulation of fatty acid beta-oxidation", "d": ["Any process that modulates the frequency, rate or extent of fatty acid bbeta-oxidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048497", "l": "maintenance of floral organ identity", "d": ["The process in which the identity of a floral organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051160", "l": "L-xylitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0090354", "l": "regulation of auxin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0014014", "l": "negative regulation of gliogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006120", "l": "mitochondrial electron transport, NADH to ubiquinone", "d": ["The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.661622235043069", "identifiers": [{"i": "GO:0051336", "l": "regulation of hydrolase activity", "d": ["Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0036213", "l": "contractile ring contraction", "d": ["The process of an actomyosin ring getting smaller in diameter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000915", "l": "regulation of glucuronoxylan catabolic process", "d": ["Any process that modulates the frequency, rate or extent of glucuronoxylan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903345", "l": "negative regulation of protein polyglycylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein polyglycylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0030834", "l": "regulation of actin filament depolymerization", "d": ["Any process that modulates the frequency, rate or extent of the disassembly of actin filaments by the removal of actin monomers from a filament."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903929", "l": "primary palate development", "d": ["The process whose specific outcome is the progression of a primary palate over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046438", "l": "D-cysteine metabolic process", "d": ["The chemical reactions and pathways involving D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.180129424388433", "identifiers": [{"i": "GO:0044255", "l": "cellular lipid metabolic process", "d": ["The chemical reactions and pathways involving lipids, as carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042680", "l": "compound eye cone cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007412", "l": "axon target recognition", "d": ["The process in which an axon recognizes and binds to a set of cells with which it may form stable connections."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140357", "l": "heme export from vacuole to cytoplasm", "d": ["The directed movement of heme from inside the vacuole across the vacuolar membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010189", "l": "vitamin E biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0007019", "l": "microtubule depolymerization", "d": ["The removal of tubulin heterodimers from one or both ends of a microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0048582", "l": "positive regulation of post-embryonic development", "d": ["Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030209", "l": "dermatan sulfate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051775", "l": "response to redox state", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072671", "l": "mitochondria-associated ubiquitin-dependent protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of proteins transported from mitochondria and targeted to cytoplasmic proteasomes for degradation as a response to oxidative stress conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035081", "l": "induction of programmed cell death by hormones", "d": ["Any process induced by hormones that directly activates any of the steps required for programmed cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042948", "l": "salicin transport", "d": ["The directed movement of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018084", "l": "peptidyl-lactic acid biosynthetic process from peptidyl-serine", "d": ["The modification of N-terminal peptidyl-serine to lactic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0140253", "l": "cell-cell fusion", "d": ["A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018137", "l": "peptide cross-linking via glycine thiazolecarboxylic acid", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl glycine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060446", "l": "branching involved in open tracheal system development", "d": ["The process in which the anatomical structures of branches in the open tracheal system are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042340", "l": "keratan sulfate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034994", "l": "microtubule organizing center attachment site organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center attachment site. A microtubule organizing center attachment site is a region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009052", "l": "pentose-phosphate shunt, non-oxidative branch", "d": ["The branch of the pentose-phosphate shunt which does not involve oxidation reactions. It comprises a series of sugar phosphate interconversions, starting with ribulose 5-P and producing fructose 6-P and glyceraldehyde 3-P."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071249", "l": "cellular response to nitrate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0034620", "l": "cellular response to unfolded protein", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002569", "l": "somatic diversification of immune receptors by N region addition", "d": ["The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin and T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the immune receptor gene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035533", "l": "positive regulation of chemokine (C-C motif) ligand 6 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.193892402340154", "identifiers": [{"i": "GO:0045892", "l": "negative regulation of DNA-templated transcription", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007175", "l": "negative regulation of epidermal growth factor-activated receptor activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042904", "l": "9-cis-retinoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 9-cis-retinoic acid, a metabolically active vitamin A derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098778", "l": "curli subunit secretion coupled to curli assembly", "d": ["The secretion of soluble curli subunits through the outer membrane, coupled to nucleation of curli fiber formation at the membrane surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0014910", "l": "regulation of smooth muscle cell migration", "d": ["Any process that modulates the frequency, rate or extent of smooth muscle cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003194", "l": "sinoatrial valve formation", "d": ["The developmental process pertaining to the initial formation of the sinoatrial valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0016479", "l": "negative regulation of transcription by RNA polymerase I", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0006278", "l": "RNA-templated DNA biosynthetic process", "d": ["A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:1905207", "l": "regulation of cardiocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of cardiocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000209", "l": "regulation of anoikis", "d": ["Any process that modulates the frequency, rate or extent of anoikis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903536", "l": "positive regulation of lactose biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of lactose biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0006768", "l": "biotin metabolic process", "d": ["The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901894", "l": "regulation of ATPase-coupled calcium transmembrane transporter activity", "d": ["Any process that modulates the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031221", "l": "arabinan metabolic process", "d": ["The chemical reactions and pathways involving arabinan, a polysaccharide composed of arabinose residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048785", "l": "hatching gland development", "d": ["The process whose specific outcome is the progression of the hatching gland over time, from its formation to the mature structure. The cells of the hatching gland contain enzymes responsible for solubilization of the egg chorion, facilitating the hatching process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905454", "l": "negative regulation of myeloid progenitor cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900829", "l": "D-tyrosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903719", "l": "regulation of I-kappaB phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of I-kappaB phosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0045776", "l": "negative regulation of blood pressure", "d": ["Any process in which the force of blood traveling through the circulatory system is decreased."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021981", "l": "subpallium radially oriented migration", "d": ["The migration of cells in the developing subpallium in which cells move from the ventricular and/or subventricular zone toward the surface of the brain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002159", "l": "desmosome assembly", "d": ["A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000098", "l": "sulfur amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0055023", "l": "positive regulation of cardiac muscle tissue growth", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904465", "l": "negative regulation of matrix metallopeptidase secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of matrix metallopeptidase secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0033028", "l": "myeloid cell apoptotic process", "d": ["Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075287", "l": "positive regulation of sporangiospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044499", "l": "envenomation resulting in positive regulation of blood pressure in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant increase of the force with which blood travels through the circulatory system of the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000277", "l": "positive regulation of oxidative phosphorylation uncoupler activity", "d": ["Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation uncoupler activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002143", "l": "tRNA wobble position uridine thiolation", "d": ["The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043483", "l": "anthocyanin biosynthetic process involved in anthocyanin accumulation in response to UV light", "d": ["The chemical reactions and pathways resulting in the formation of the pigment anthocyanin, contributing to anthocyanin accumulation in a tissue in response to a UV light stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007359", "l": "posterior abdomen determination", "d": ["The regionalization process in which the posterior (abdominal) regions of the embryo are specified by the gap genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905609", "l": "positive regulation of smooth muscle cell-matrix adhesion", "d": ["Any process that activates or increases the frequency, rate or extent of smooth muscle cell-matrix adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010878", "l": "cholesterol storage", "d": ["The accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1900429", "l": "negative regulation of filamentous growth of a population of unicellular organisms", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072688", "l": "SHREC complex localization", "d": ["Any process in which a SHREC complex is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002561", "l": "basophil degranulation", "d": ["The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044574", "l": "starch utilization system complex assembly", "d": ["The aggregation, arrangement and bonding together of the starch utilization system complex, a complex of cell envelope-associated proteins that degrades glycan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.777964009505382", "identifiers": [{"i": "GO:1905330", "l": "regulation of morphogenesis of an epithelium", "d": ["Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035221", "l": "genital disc pattern formation", "d": ["The process that gives rise to the patterns of cell differentiation that will arise in the genital imaginal disc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018268", "l": "GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036289", "l": "peptidyl-serine autophosphorylation", "d": ["The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine residue on an identical protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905069", "l": "allantois development", "d": ["The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900293", "l": "positive regulation of galactotriose transport", "d": ["Any process that activates or increases the frequency, rate or extent of galactotriose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901163", "l": "regulation of trophoblast cell migration", "d": ["Any process that modulates the frequency, rate or extent of trophoblast cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009091", "l": "homoserine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of homoserine, alpha-amino-gamma-hydroxybutyric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046256", "l": "2,4,6-trinitrotoluene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0010958", "l": "regulation of amino acid import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of amino acid import into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904648", "l": "cellular response to rotenone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052103", "l": "induction by symbiont of host induced systemic resistance", "d": ["Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902498", "l": "regulation of protein autoubiquitination", "d": ["Any process that modulates the frequency, rate or extent of protein autoubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046682", "l": "response to cyclodiene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclodiene stimulus. A cyclodiene is any organic insecticide (as dieldrin or chlordane) with a chlorinated methylene group forming a bridge across a 6-membered carbon ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1904029", "l": "regulation of cyclin-dependent protein kinase activity", "d": ["Any process that modulates the frequency, rate or extent of cyclin-dependent protein kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097172", "l": "N-acetylmuramic acid metabolic process", "d": ["The chemical reactions and pathways involving N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0097639", "l": "L-lysine import across plasma membrane", "d": ["The directed movement of L-lysine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018187", "l": "molybdenum incorporation via L-cysteinyl molybdopterin guanine dinucleotide", "d": ["The incorporation of molybdenum into a protein by L-cysteinyl molybdopterin guanine dinucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0045763", "l": "negative regulation of cellular amino acid metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0018277", "l": "protein deamination", "d": ["The removal of an amino group from a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019551", "l": "glutamate catabolic process to 2-oxoglutarate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including 2-oxoglutarate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075242", "l": "negative regulation of zoospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905395", "l": "response to flavonoid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009386", "l": "translational attenuation", "d": ["Translational attenuation is a regulatory mechanism analogous to ribosome-mediated transcriptional attenuation. The system requires the presence of a short ORF, called a leader peptide, encoded in the mRNA upstream of the ribosome-binding site and start codon of the gene whose translation is to be regulated. Certain conditions, such as presence of the antibiotic tetracycline in bacteria or amino acid starvation, may cause slowing or stalling of the ribosome translating the leader peptide. The stalled ribosome masks a region of the mRNA and affects which of two alternative mRNA folded structures will form, therefore controlling whether or not a ribosome will bind and initiate translation of the downstream gene. Translational attenuation is analogous to ribosome-mediated transcriptional attenuation, in which mRNA remodeling caused by ribosome stalling regulates transcriptional termination rather than translational initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905912", "l": "regulation of calcium ion export across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0000466", "l": "maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044469", "l": "envenomation resulting in positive regulation of blood coagulation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of blood coagulation in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903525", "l": "regulation of membrane tubulation", "d": ["Any process that modulates the frequency, rate or extent of membrane tubulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015720", "l": "allantoin transport", "d": ["The directed movement of allantoin, (2,5-dioxo-4-imidazolidinyl)urea, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0002568", "l": "somatic diversification of T cell receptor genes", "d": ["The somatic process that results in the generation of sequence diversity of T cell receptor genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097270", "l": "dishabituation", "d": ["The temporary recovery of response to a stimulus when a novel stimulus is added."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0060306", "l": "regulation of membrane repolarization", "d": ["Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071307", "l": "cellular response to vitamin K", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061102", "l": "stomach neuroendocrine cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045227", "l": "capsule polysaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006033", "l": "chitin localization", "d": ["A process in which chitin is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0045577", "l": "regulation of B cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of B cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062052", "l": "starch granule initiation", "d": ["The sequence of events that initiates (or primes) the synthesis of semi-crystalline starch granules within photosynthetic chloroplasts or non-photosynthetic amyloplasts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000429", "l": "negative regulation of neutrophil aggregation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil aggregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903772", "l": "regulation of viral budding via host ESCRT complex", "d": ["Any process that modulates the frequency, rate or extent of viral budding via host ESCRT complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019569", "l": "L-arabinose catabolic process to xylulose 5-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including xylulose 5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031585", "l": "regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity", "d": ["Any process that modulates the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0043695", "l": "detection of pheromone", "d": ["The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990108", "l": "protein linear deubiquitination", "d": ["A protein deubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is removed from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097308", "l": "cellular response to farnesol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051610", "l": "serotonin uptake", "d": ["The directed movement of serotonin into a cell, typically presynaptic neurons or glial cells. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0050684", "l": "regulation of mRNA processing", "d": ["Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061360", "l": "optic chiasma development", "d": ["The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061766", "l": "positive regulation of lung blood pressure", "d": ["The process that increases the force with which blood travels through the lungs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046286", "l": "flavonoid phytoalexin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070598", "l": "cell wall (1->3)-alpha-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-glucosidic bonds, found in the walls of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080189", "l": "primary growth", "d": ["Growth of a plant structure from the time of its initiation by an apical meristem until its expansion is completed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009221", "l": "pyrimidine deoxyribonucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0052325", "l": "cell wall pectin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106016", "l": "positive regulation of inflammatory response to wounding", "d": ["Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046952", "l": "ketone body catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902845", "l": "negative regulation of mitotic spindle elongation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007073", "l": "positive regulation of transcription involved in exit from mitosis, from RNA polymerase I promoter", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase I promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050929", "l": "induction of negative chemotaxis", "d": ["Any process that initiates the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046453", "l": "dipyrrin metabolic process", "d": ["The chemical reactions and pathways involving dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060933", "l": "His-Purkinje system cell development", "d": ["The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051965", "l": "positive regulation of synapse assembly", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000266", "l": "regulation of blood coagulation, intrinsic pathway", "d": ["Any process that modulates the frequency, rate or extent of blood coagulation, intrinsic pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0019852", "l": "L-ascorbic acid metabolic process", "d": ["The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.666259479937736", "identifiers": [{"i": "GO:0034470", "l": "ncRNA processing", "d": ["Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046092", "l": "deoxycytidine metabolic process", "d": ["The chemical reactions and pathways involving deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.193892402340154", "identifiers": [{"i": "GO:0014020", "l": "primary neural tube formation", "d": ["The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0043457", "l": "regulation of cellular respiration", "d": ["Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0030639", "l": "polyketide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034379", "l": "very-low-density lipoprotein particle assembly", "d": ["The non-covalent aggregation and arrangement of proteins and lipids in the liver to form a very-low-density lipoprotein particle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098039", "l": "replicative DNA transposition", "d": ["Process of transposition in which the existing element is replicated and one of the copies is excised and integrated at a new target site. Also referred to as copy-and-paste transposition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043508", "l": "negative regulation of JUN kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0106011", "l": "regulation of protein localization to medial cortex", "d": ["Any process that regulates the localization of a protein to the medial cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072658", "l": "maintenance of protein location in membrane", "d": ["Any process in which a protein is maintained in a specific location in a membrane, and is prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0014857", "l": "regulation of skeletal muscle cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032471", "l": "negative regulation of endoplasmic reticulum calcium ion concentration", "d": ["Any process that decreases the concentration of calcium ions in the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905608", "l": "positive regulation of presynapse assembly", "d": ["Any process that activates or increases the frequency, rate or extent of presynapse assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905328", "l": "plant septum development", "d": ["The process whose specific outcome is the progression of a septum over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002627", "l": "positive regulation of T cell antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052005", "l": "suppression by symbiont of host ethylene-mediated defense response", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031384", "l": "regulation of initiation of mating projection growth", "d": ["Any process that modulates the frequency, rate, or extent of the start of mating projection formation by unicellular fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901209", "l": "positive regulation of heart looping", "d": ["Any process that activates or increases the frequency, rate or extent of heart looping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046287", "l": "isoflavonoid metabolic process", "d": ["The chemical reactions and pathways involving isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids, containing a flavan skeleton. They are differentiated from flavonoids by the point of attachment of the aromatic ring group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061789", "l": "dense core granule priming", "d": ["A process that converts unprimed dense core granules (DCVs) to a pool of primed vesicles that are capable of fusing with the plasma membrane (fusion-competent) and thereby releasing their contents. Priming typically occurs after docking."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0050748", "l": "negative regulation of lipoprotein metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042728", "l": "flavin-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.116918913335823", "identifiers": [{"i": "GO:0000377", "l": "RNA splicing, via transesterification reactions with bulged adenosine as nucleophile", "d": ["Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048714", "l": "positive regulation of oligodendrocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006649", "l": "phospholipid transfer to membrane", "d": ["The transfer of a phospholipid from its site of synthesis to the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035983", "l": "response to trichostatin A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002730", "l": "regulation of dendritic cell cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032889", "l": "regulation of vacuole fusion, non-autophagic", "d": ["Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904831", "l": "positive regulation of aortic smooth muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006794", "l": "phosphorus utilization", "d": ["A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary phosphorus source and then activates genes to scavenge the last traces of the primary phosphorus source and to transport and metabolize alternative phosphorus sources. The utilization process begins when the cell or organism detects phosphorus levels, includes the phosphorus-containing substances, and ends when phosphorus is incorporated into the cell or organism's metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045497", "l": "female analia development", "d": ["The process whose specific outcome is the progression of the analia of the female over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070898", "l": "RNA polymerase III preinitiation complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase III promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045694", "l": "regulation of embryo sac egg cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of embryo sac egg cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071960", "l": "maintenance of mitotic sister chromatid cohesion, centromeric", "d": ["The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006107", "l": "oxaloacetate metabolic process", "d": ["The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044832", "l": "induction by virus of host cytokine production", "d": ["The process in which a virus increases the frequency, rate or extent of cytokine production in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019447", "l": "D-cysteine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061112", "l": "negative regulation of bud outgrowth involved in lung branching", "d": ["Any process that decreases the rate, frequency, or extent of bud outgrowth involved in lung branching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0002902", "l": "regulation of B cell apoptotic process", "d": ["Any process that modulates the frequency, rate, or extent of B cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006253", "l": "dCTP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dCTP, deoxycytidine triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018978", "l": "anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process", "d": ["The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated, broad spectrum, contact insecticide, in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901704", "l": "L-glutamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-glutamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048692", "l": "negative regulation of axon extension involved in regeneration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905124", "l": "negative regulation of glucosylceramidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucosylceramidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904394", "l": "negative regulation of skeletal muscle acetylcholine-gated channel clustering", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018287", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide", "d": ["The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0036115", "l": "fatty-acyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048251", "l": "elastic fiber assembly", "d": ["Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902119", "l": "regulation of meiotic spindle elongation", "d": ["Any process that modulates the frequency, rate or extent of meiotic spindle elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1905268", "l": "negative regulation of chromatin organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904539", "l": "negative regulation of glycolytic process through fructose-6-phosphate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glycolytic process through fructose-6-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048672", "l": "positive regulation of collateral sprouting", "d": ["Any process that activates or increases the frequency, rate or extent of collateral sprouting."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.232064878529073", "identifiers": [{"i": "GO:0022029", "l": "telencephalon cell migration", "d": ["The orderly movement of a cell from one site to another at least one of which is located in the telencephalon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905888", "l": "negative regulation of cellular response to very-low-density lipoprotein particle stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000625", "l": "regulation of miRNA catabolic process", "d": ["Any process that modulates the frequency, rate or extent of miRNA catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048750", "l": "compound eye corneal lens morphogenesis", "d": ["The process in which the anatomical structures of the compound eye corneal lens are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021662", "l": "rhombomere 4 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 4. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0002653", "l": "negative regulation of tolerance induction dependent upon immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction dependent upon immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.443919496911477", "identifiers": [{"i": "GO:0051235", "l": "maintenance of location", "d": ["Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000586", "l": "regulation of platelet-derived growth factor receptor-beta signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000613", "l": "negative regulation of thyroid-stimulating hormone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of thyroid-stimulating hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060185", "l": "outer ear unfolding", "d": ["The opening and spreading out of the outer ear."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018267", "l": "GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-cysteine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a cysteinyl-peptide bond in the carboxy-terminal region of a membrane-associated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0120187", "l": "positive regulation of protein localization to chromatin", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to chromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033762", "l": "response to glucagon", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000859", "l": "negative regulation of aldosterone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aldosterone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035780", "l": "CD80 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CD80, a CD marker that occurs on antigen presenting cells such as activated B cells and monocytes that provides a co-stimulatory signal necessary for T cell activation and survival."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:2000515", "l": "negative regulation of CD4-positive, alpha-beta T cell activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090024", "l": "negative regulation of neutrophil chemotaxis", "d": ["Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120060", "l": "regulation of gastric emptying", "d": ["Any process that modulates the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061911", "l": "amphisome-lysosome fusion", "d": ["The process in which amphisomes fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the amphisome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019917", "l": "peptidyl-D-alanine racemization via peptidyl-L-serine", "d": ["The dehydration of peptidyl-serine, followed by hydrogenation to produce peptidyl-D-alanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.749738076122242", "identifiers": [{"i": "GO:0098662", "l": "inorganic cation transmembrane transport", "d": ["A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900605", "l": "tensidol A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tensidol A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903082", "l": "positive regulation of C-C chemokine receptor CCR7 signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0006405", "l": "RNA export from nucleus", "d": ["The directed movement of RNA from the nucleus to the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043308", "l": "eosinophil degranulation", "d": ["The regulated exocytosis of secretory granules containing preformed mediators such as major basic protein, eosinophil peroxidase, and eosinophil cationic protein by an eosinophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0001109", "l": "promoter clearance during DNA-templated transcription", "d": ["Any process involved in the transition from the initiation to the elongation phases of transcription by a DNA-dependent RNA polymerase, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002817", "l": "negative regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051886", "l": "negative regulation of timing of anagen", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045683", "l": "negative regulation of epidermis development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0014827", "l": "intestine smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0036037", "l": "CD8-positive, alpha-beta T cell activation", "d": ["The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080156", "l": "mitochondrial mRNA modification", "d": ["The covalent alteration within the mitochondrion of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106115", "l": "negative regulation of mitotic cohesin dsDNA (leading strand) loading", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071493", "l": "cellular response to UV-B", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900880", "l": "18-methylnonadec-1-ene metabolic process", "d": ["The chemical reactions and pathways involving 18-methylnonadec-1-ene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000156", "l": "regulation of retrograde vesicle-mediated transport, Golgi to ER", "d": ["Any process that modulates the frequency, rate or extent of retrograde vesicle-mediated transport, Golgi to ER."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071376", "l": "cellular response to corticotropin-releasing hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031586", "l": "negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903110", "l": "regulation of single-strand break repair via homologous recombination", "d": ["Any process that modulates the frequency, rate or extent of single-strand break repair via homologous recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0031566", "l": "actomyosin contractile ring maintenance", "d": ["The cell cycle process in which the contractile ring is maintained in response to the cytokinesis checkpoint; that is when cytokinesis is delayed awaiting completion of nuclear division or the correct formation of cytokinetic structures. This process occurs in the context of cytokinesis that takes place as part of a cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904072", "l": "presynaptic active zone disassembly", "d": ["The disaggregation of a presynaptic active zone into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009903", "l": "chloroplast avoidance movement", "d": ["The relocation process in which chloroplasts in photosynthetic cells avoid strong light and move away from it in order to preserve the photosynthetic machinery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900175", "l": "regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry", "d": ["Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098678", "l": "viral tropism switching", "d": ["A process by which the range of hosts which a virus can bind and infect is changed. Examples include phages that switch between types of fibers via the action of a virally encoded invertase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0075054", "l": "modulation of penetration peg formation", "d": ["Any process that modulates the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904052", "l": "negative regulation of protein targeting to vacuole involved in autophagy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuole involved in autophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061549", "l": "sympathetic ganglion development", "d": ["The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002802", "l": "positive regulation of antifungal peptide secretion", "d": ["Any process that activates or increases the frequency, rate, or extent of antifungal peptide secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033103", "l": "protein secretion by the type VI secretion system", "d": ["The process in which proteins are transferred into the extracellular milieu or directly into host cells by the type VI secretion system. Proteins secreted by this system do not require an N-terminal signal sequence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903450", "l": "regulation of G1 to G0 transition", "d": ["Any process that modulates the frequency, rate or extent of G1 to G0 transition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0019731", "l": "antibacterial humoral response", "d": ["An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097170", "l": "ADP-L-glycero-beta-D-manno-heptose metabolic process", "d": ["The chemical reactions and pathways involving ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0014016", "l": "neuroblast differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032900", "l": "negative regulation of neurotrophin production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of a neurotrophin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097723", "l": "amoeboid sperm motility", "d": ["Any process involved in the controlled movement of an amoeboid sperm cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903922", "l": "negative regulation of protein processing in phagocytic vesicle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein processing in phagocytic vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.977148804244202", "identifiers": [{"i": "GO:0060047", "l": "heart contraction", "d": ["The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006025", "l": "galactosaminoglycan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031119", "l": "tRNA pseudouridine synthesis", "d": ["The intramolecular conversion of uridine to pseudouridine in a tRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090610", "l": "bundle sheath cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a bundle sheath cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072635", "l": "interleukin-31 production", "d": ["The appearance of interleukin-31 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905350", "l": "Y-shaped link assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a Y-shaped link. Two distinct protein complexes are known to be involved in proper linker assembly: the MKS complex and the NPHP complex. Improper assembly of Y-shaped links may cause malfunctioning of the transition zone as a molecular gate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019307", "l": "mannose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032824", "l": "negative regulation of natural killer cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120184", "l": "negative regulation of focal adhesion disassembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a focal adhesion into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900825", "l": "regulation of membrane depolarization during cardiac muscle cell action potential", "d": ["Any process that modulates the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902723", "l": "negative regulation of skeletal muscle satellite cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905089", "l": "regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization", "d": ["Any process that modulates the frequency, rate or extent of a parkin-mediated process that positively regulates mitophagy in response to mitochondrial depolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075188", "l": "regulation of hyphopodium formation", "d": ["Any process that modulates the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0039514", "l": "disruption by virus of host JAK-STAT cascade", "d": ["Any process in which a virus interferes with the JAK-STAT signal cascade in the host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018875", "l": "anaerobic benzoate metabolic process", "d": ["The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905231", "l": "cellular response to borneol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902906", "l": "proteasome storage granule assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a proteasome storage granule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051068", "l": "dihydrolipoamide metabolic process", "d": ["The chemical reactions and pathways involving dihydrolipoamide, the reduced form of lipoamide, produced as an intermediate in the reactions in which lipoamide acts as a cofactor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033056", "l": "D-ornithine metabolic process", "d": ["The chemical reactions and pathways involving D-ornithine, the D-enantiomer of the amino acid ornithine, i.e. (2R)-2,5-diaminopentanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0021766", "l": "hippocampus development", "d": ["The progression of the hippocampus over time from its initial formation until its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1903314", "l": "regulation of nitrogen cycle metabolic process", "d": ["Any process that modulates the frequency, rate or extent of nitrogen cycle metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009256", "l": "10-formyltetrahydrofolate metabolic process", "d": ["The chemical reactions and pathways involving 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.021452276279312", "identifiers": [{"i": "GO:0098660", "l": "inorganic ion transmembrane transport", "d": ["The process in which an inorganic ion is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990911", "l": "response to psychosocial stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to aversive or demanding psychological and social conditions that tax or exceed the behavioral resources of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901345", "l": "response to L-thialysine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072565", "l": "endothelial microparticle formation", "d": ["The cellular component organization process in which microparticles bud off from an endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061294", "l": "mesonephric renal vesicle induction", "d": ["Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the mesonephric renal vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905781", "l": "negative regulation of phosphatidylserine exposure on apoptotic cell surface", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:2000403", "l": "positive regulation of lymphocyte migration", "d": ["Any process that activates or increases the frequency, rate or extent of lymphocyte migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051976", "l": "lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate", "d": ["The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.465174152298118", "identifiers": [{"i": "GO:0140527", "l": "reciprocal homologous recombination", "d": ["A DNA recombination process that results in the bidirectional exchange of genetic material between highly homologous DNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031031", "l": "positive regulation of septation initiation signaling", "d": ["Any process that activates or increases the frequency, rate or extent of septation initiation signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0060033", "l": "anatomical structure regression", "d": ["The developmental process in which an anatomical stucture is destroyed as a part of its normal progression."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046419", "l": "octopine metabolic process", "d": ["The chemical reactions and pathways involving octopine, (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033386", "l": "geranylgeranyl diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of geranylgeranyl diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905378", "l": "cellular response to D-galactose", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0033262", "l": "regulation of nuclear cell cycle DNA replication", "d": ["Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902787", "l": "cellular response to dodecane", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032740", "l": "positive regulation of interleukin-17 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1903726", "l": "negative regulation of phospholipid metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042595", "l": "behavioral response to starvation", "d": ["Any process that results in a change in the behavior of an organism as a result of deprivation of nourishment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903395", "l": "regulation of secondary cell septum biogenesis", "d": ["Any process that modulates the frequency, rate or extent of secondary cell septum biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900235", "l": "negative regulation of Kit signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Kit signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051414", "l": "response to cortisol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0032958", "l": "inositol phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:0098801", "l": "regulation of renal system process", "d": ["Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046963", "l": "3'-phosphoadenosine 5'-phosphosulfate transport", "d": ["The directed movement of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033082", "l": "regulation of extrathymic T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of extrathymic T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:1900101", "l": "regulation of endoplasmic reticulum unfolded protein response", "d": ["Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031150", "l": "sorocarp stalk development", "d": ["The process whose specific outcome is the progression of the sorocarp stalk over time, from its formation to the mature structure. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070814", "l": "hydrogen sulfide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0019758", "l": "glycosinolate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075250", "l": "negative regulation of aeciospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903073", "l": "negative regulation of death-inducing signaling complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of death-inducing signaling complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021935", "l": "cerebellar granule cell precursor tangential migration", "d": ["The early migration of granule cell precursors in which cells move orthogonal to the direction of radial migration and ultimately cover the superficial zone of the cerebellar primordium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072153", "l": "renal interstitial fibroblast fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a renal fibroblast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900952", "l": "positive regulation of 18-methylnonadec-1-ene biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0032328", "l": "alanine transport", "d": ["The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071718", "l": "sodium-independent icosanoid transport", "d": ["The directed, sodium-independent, movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072284", "l": "metanephric S-shaped body morphogenesis", "d": ["The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0010359", "l": "regulation of anion channel activity", "d": ["Any process that modulates the frequency, rate or extent of anion channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097037", "l": "heme export", "d": ["The directed movement of heme out of a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140245", "l": "regulation of translation at postsynapse", "d": ["Any process that regulates translation occurring at the postsynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071389", "l": "cellular response to mineralocorticoid stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000238", "l": "regulation of tRNA export from nucleus", "d": ["Any process that modulates the frequency, rate or extent of tRNA export from nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019044", "l": "maintenance of viral latency", "d": ["The perpetuation of a latent state, generally by repressing the viruses own lytic genes expression and ensuring expression of viral genes which function to keep the viral genome from being detected by the host defense mechanisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001930", "l": "positive regulation of exocyst assembly", "d": ["Any process that increases the rate or extent of exocyst assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120278", "l": "negative regulation of cerebral blood circulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0086053", "l": "AV node cell to bundle of His cell communication by electrical coupling", "d": ["The process that mediates signaling interactions between an AV node cardiomyocyte and a bundle of His cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0044090", "l": "positive regulation of vacuole organization", "d": ["Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061945", "l": "regulation of protein K48-linked ubiquitination", "d": ["Any process that modulates the rate, frequency or extent of protein K-48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071236", "l": "cellular response to antibiotic", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099190", "l": "postsynaptic spectrin-associated cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of spectrin-associated cytoskeleton and associated proteins in the postsynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021937", "l": "cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation", "d": ["The process that mediates the transfer of information from Purkinje cells to granule cell precursors resulting in an increase in rate of granule cell precursor cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0034605", "l": "cellular response to heat", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072306", "l": "positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis", "d": ["Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075120", "l": "disruption of host G protein-coupled receptor signal transduction", "d": ["Any process in which a symbiont interferes with host G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.470950656012619", "identifiers": [{"i": "GO:0000272", "l": "polysaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:1900150", "l": "regulation of defense response to fungus", "d": ["Any process that modulates the frequency, rate or extent of defense response to fungus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.685364931984026", "identifiers": [{"i": "GO:0043446", "l": "cellular alkane metabolic process", "d": ["The chemical reactions and pathways involving an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, as carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903581", "l": "regulation of basophil degranulation", "d": ["Any process that modulates the frequency, rate or extent of basophil degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0009411", "l": "response to UV", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042418", "l": "epinephrine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039698", "l": "polyadenylation of viral mRNA by polymerase stuttering", "d": ["Polyadenylation of viral mRNA through a polymerase stuttering mechanism. The stop signal present at the end of each gene comprises a stretch of uridine on which the viral polymerase acquires a stuttering behavior: after each adenine inserted, the polymerase moves back one nucleotide along with the mRNA. It resumes transcription adding a new adenine, then again moves back, thereby producing a polyA tail."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0030187", "l": "melatonin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904883", "l": "negative regulation of telomerase catalytic core complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomerase catalytic core complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030543", "l": "2-micrometer plasmid partitioning", "d": ["The process in which copies of the 2-micrometer plasmid, found in fungi such as Saccharomyces, are distributed to daughter cells upon cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.356257019993834", "identifiers": [{"i": "GO:0050907", "l": "detection of chemical stimulus involved in sensory perception", "d": ["The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031284", "l": "positive regulation of guanylate cyclase activity", "d": ["Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002155", "l": "regulation of thyroid hormone mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of a thyroid hormone mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902601", "l": "silver ion transmembrane transport", "d": ["The directed movement of silver ion across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070998", "l": "sensory perception of gravity", "d": ["The series of events required for an organism to receive a gravitational stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071915", "l": "protein-lysine lysylation", "d": ["The addition of lysine group to a lysine residue in a protein, producing N6-(lysyl)-L-lysine. This modification is observed in, and is probably unique to, translation elongation factor P (EF-P)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.565791298371025", "identifiers": [{"i": "GO:0007599", "l": "hemostasis", "d": ["The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070183", "l": "mitochondrial tryptophanyl-tRNA aminoacylation", "d": ["The process of coupling tryptophan to tryptophanyl-tRNA in a mitochondrion, catalyzed by tryptophanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000597", "l": "positive regulation of optic nerve formation", "d": ["Any process that activates or increases the frequency, rate or extent of optic nerve formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000738", "l": "positive regulation of stem cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of stem cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042350", "l": "GDP-L-fucose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0061900", "l": "glial cell activation", "d": ["A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:1901077", "l": "regulation of relaxation of muscle", "d": ["Any process that modulates the frequency, rate or extent of relaxation of muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048544", "l": "recognition of pollen", "d": ["A cell recognition process in which pollen is recognized and either accepted or rejected by cells in the stigma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019509", "l": "L-methionine salvage from methylthioadenosine", "d": ["The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070480", "l": "exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-independent decay", "d": ["The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs independent of deadenylation, but requires decapping followed by transcript decay."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1903692", "l": "methionine import across plasma membrane", "d": ["The directed movement of methionine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072681", "l": "fibronectin-dependent thymocyte migration", "d": ["The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on fibronectin in the extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048866", "l": "stem cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042258", "l": "molybdenum incorporation via L-serinyl molybdopterin guanine dinucleotide", "d": ["The incorporation of molybdenum into a protein via L-serinyl molybdopterin guanine dinucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1902991", "l": "regulation of amyloid precursor protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of amyloid precursor protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0039003", "l": "pronephric field specification", "d": ["The process in which regions of the embryo are delineated into the area in which the pronephric kidney will develop."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071245", "l": "cellular response to carbon monoxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900296", "l": "positive regulation of heptasaccharide transport", "d": ["Any process that activates or increases the frequency, rate or extent of heptasaccharide transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0061171", "l": "establishment of bipolar cell polarity", "d": ["The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901098", "l": "positive regulation of autophagosome maturation", "d": ["Any process that activates or increases the frequency, rate or extent of autophagosome maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0001660", "l": "fever generation", "d": ["The heat generation process that results in a rise in body temperature above the normal, often as a response to infection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000768", "l": "positive regulation of nephron tubule epithelial cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044490", "l": "positive regulation of voltage-gated sodium channel activity in another organism", "d": ["Any process that activates or increases the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045780", "l": "positive regulation of bone resorption", "d": ["Any process that activates or increases the frequency, rate or extent of bone resorption."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034631", "l": "microtubule anchoring at spindle pole body", "d": ["Any process in which a microtubule is maintained in a specific location in a cell by attachment to a spindle pole body. Microtubules attach to spindle pole bodies at the minus end."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045138", "l": "nematode male tail tip morphogenesis", "d": ["The process in which the anatomical structure of the adult male tail tip is generated and organized. In some species of rhabitid nematodes, the male tail tip undergoes a morphological change such that the most posterior hypodermal cells in the tail (hyp8-11 in C. elegans) fuse and retract anteriorly, changing the shape of the tail from a pointed, tapered cone, or spike, to a rounded, blunt dome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042187", "l": "p-xylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022036", "l": "rhombomere cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a rhombomere cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072435", "l": "response to mitotic G2 DNA damage checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of mitotic G2/M transition DNA damage checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0005980", "l": "glycogen catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034616", "l": "response to laminar fluid shear stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1903175", "l": "fatty alcohol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fatty alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051524", "l": "cell growth mode switching, bipolar to monopolar", "d": ["The process in which a cell switches from bipolar cell growth to monopolar cell growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045962", "l": "positive regulation of development, heterochronic", "d": ["Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and increases the rate at which this time point is reached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033049", "l": "clavulanic acid metabolic process", "d": ["The chemical reactions and pathways involving clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001204", "l": "regulation of osteoclast development", "d": ["Any process that modulates the frequency, rate or extent of osteoclast development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019316", "l": "D-allose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0032369", "l": "negative regulation of lipid transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0021517", "l": "ventral spinal cord development", "d": ["The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0043137", "l": "DNA replication, removal of RNA primer", "d": ["Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905342", "l": "positive regulation of protein localization to kinetochore", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to kinetochore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051948", "l": "negative regulation of glutamate uptake involved in transmission of nerve impulse", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902133", "l": "(+)-secoisolariciresinol metabolic process", "d": ["The chemical reactions and pathways involving (+)-secoisolariciresinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060981", "l": "cell migration involved in coronary angiogenesis", "d": ["The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0018410", "l": "C-terminal protein amino acid modification", "d": ["The alteration of the C-terminal amino acid residue in a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090301", "l": "negative regulation of neural crest formation", "d": ["Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000380", "l": "alternative mRNA splicing, via spliceosome", "d": ["The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1900180", "l": "regulation of protein localization to nucleus", "d": ["Any process that modulates the frequency, rate or extent of protein localization to nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043553", "l": "negative regulation of phosphatidylinositol 3-kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylinositol 3-kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.415093686714229", "identifiers": [{"i": "GO:0061351", "l": "neural precursor cell proliferation", "d": ["The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0001878", "l": "response to yeast", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905223", "l": "epicardium morphogenesis", "d": ["The developmental process by which an epicardium is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007291", "l": "sperm individualization", "d": ["The resolution of the male germline syncytium or cyst into individual gametes by packaging each spermatid into its own plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070292", "l": "N-acylphosphatidylethanolamine metabolic process", "d": ["The chemical reactions and pathways involving N-acylphosphatidylethanolamines. An N-acylphosphatidylethanolamine is a phosphatidylethanolamine substituted at nitrogen by an acyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090215", "l": "regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity", "d": ["Any process that modulates the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071337", "l": "negative regulation of hair follicle cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of hair follicle cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.06379513530257", "identifiers": [{"i": "GO:0050803", "l": "regulation of synapse structure or activity", "d": ["Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015692", "l": "lead ion transport", "d": ["The directed movement of lead (Pb) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000117", "l": "regulation of transcription involved in G2/M transition of mitotic cell cycle", "d": ["Any process that regulates transcription such that the target genes are transcribed as part of the G2/M transition of the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0031952", "l": "regulation of protein autophosphorylation", "d": ["Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035862", "l": "dITP metabolic process", "d": ["The chemical reactions and pathways involving dITP (deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate). dITP is a deoxyinosine phosphate compound having a triphosphate group at the 5'-position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0000027", "l": "ribosomal large subunit assembly", "d": ["The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0034389", "l": "lipid droplet organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.943682538662635", "identifiers": [{"i": "GO:0051049", "l": "regulation of transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904388", "l": "negative regulation of ncRNA transcription associated with protein coding gene TSS/TES", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ncRNA transcription associated with protein coding gene TSS/TES."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140113", "l": "extracellular microvesicle biogenesis", "d": ["The assembly and secretion of a set of components to form an extracellular microvesicule, a membrane-bounded vesicle that ranges in size 100 nm to 1 micron in size) and exits the cell by budding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060434", "l": "bronchus morphogenesis", "d": ["The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042135", "l": "neurotransmitter catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032741", "l": "positive regulation of interleukin-18 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-18 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.510429476229447", "identifiers": [{"i": "GO:0010563", "l": "negative regulation of phosphorus metabolic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006552", "l": "leucine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of leucine, 2-amino-4-methylpentanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048171", "l": "negative regulation of long-term neuronal synaptic plasticity", "d": ["A process that decreases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0050952", "l": "sensory perception of electrical stimulus", "d": ["The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032914", "l": "positive regulation of transforming growth factor beta1 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019761", "l": "glucosinolate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098676", "l": "modulation of host virulence by virus", "d": ["A process by which a virus improves the virulence of its host for that host's respective host. Common in but not limited to bacteriophages; also occurs in phage-bearing bacteria infecting plants or animals for example. Mechanisms include the expression of factors that modulate a bacterial adhesion to a host cell, spread through host tissues, production of exotoxins or provide protection against host immune defenses."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905402", "l": "regulation of activated CD8-positive, alpha-beta T cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048910", "l": "afferent axon development in anterior lateral line nerve", "d": ["The process whose specific outcome is the progression of an afferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the anterior lateral line nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0007040", "l": "lysosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048887", "l": "cupula development", "d": ["The process whose specific outcome is the progression of the cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048203", "l": "vesicle targeting, trans-Golgi to endosome", "d": ["The process in which vesicles are directed to specific destination membranes during transport from the trans-Golgi to the endosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901417", "l": "negative regulation of response to ethanol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to ethanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0061136", "l": "regulation of proteasomal protein catabolic process", "d": ["Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048797", "l": "swim bladder formation", "d": ["The process that gives rise to the swim bladder. This process pertains to the initial formation of a structure from unspecified parts. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0006213", "l": "pyrimidine nucleoside metabolic process", "d": ["The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021686", "l": "cerebellar granular layer maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140317", "l": "export across cell outer membrane", "d": ["The directed movement of a substance across the outer membrane in cells with two membranes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0018942", "l": "organometal metabolic process", "d": ["The chemical reactions and pathways involving organometals, any metal-containing organic compound, especially one in which the metal atom is linked directly to one of more carbon atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030916", "l": "otic vesicle formation", "d": ["The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007253", "l": "cytoplasmic sequestering of NF-kappaB", "d": ["The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071961", "l": "mitotic sister chromatid cohesion, arms", "d": ["The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071716", "l": "leukotriene transport", "d": ["The directed movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904905", "l": "negative regulation of endothelial cell-matrix adhesion via fibronectin", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050970", "l": "detection of electrical stimulus involved in magnetoreception", "d": ["The series of events that contribute to magnetoception in which an electrical stimulus is received and converted into a molecular signal. The stimulus is in the form of an induced electric field resulting from movement in a magnetic field."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901839", "l": "regulation of RNA polymerase I regulatory region sequence-specific DNA binding", "d": ["Any process that modulates the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.465174152298118", "identifiers": [{"i": "GO:0010631", "l": "epithelial cell migration", "d": ["The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901756", "l": "butirosin metabolic process", "d": ["The chemical reactions and pathways involving butirosin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080113", "l": "regulation of seed growth", "d": ["Any process that modulates the frequency, rate or extent of growth of the seed of an plant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0035806", "l": "modulation of blood coagulation in another organism", "d": ["Any process in which an organism modulates the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072714", "l": "response to selenite ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080183", "l": "response to photooxidative stress", "d": ["Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a photooxidative stress, the light-dependent generation of active oxygen species. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021978", "l": "telencephalon regionalization", "d": ["The regionalization process that creates areas within the forebrain that will direct the behavior of cell migration in differentiation as the telencephalon develops."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905333", "l": "regulation of gastric motility", "d": ["Any process that modulates the frequency, rate or extent of gastric motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0042398", "l": "cellular modified amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905853", "l": "regulation of heparan sulfate binding", "d": ["Any process that modulates the frequency, rate or extent of heparan sulfate binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0070613", "l": "regulation of protein processing", "d": ["Any process that modulates the frequency, rate or extent of protein processing, a protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071637", "l": "regulation of monocyte chemotactic protein-1 production", "d": ["Any process that modulates the frequency, rate, or extent of production of monocyte chemotactic protein-1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902819", "l": "ethyl acetate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ethyl acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030642", "l": "intracellular sulfate ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of sulfate ions within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0019069", "l": "viral capsid assembly", "d": ["The assembly of a virus capsid from its protein subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.287337192553075", "identifiers": [{"i": "GO:0007606", "l": "sensory perception of chemical stimulus", "d": ["The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0033522", "l": "histone H2A ubiquitination", "d": ["The modification of histone H2A by addition of one or more ubiquitin groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903609", "l": "negative regulation of inward rectifier potassium channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of inward rectifier potassium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0043476", "l": "pigment accumulation", "d": ["The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002109", "l": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)", "d": ["Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:1903322", "l": "positive regulation of protein modification by small protein conjugation or removal", "d": ["Any process that activates or increases the frequency, rate or extent of protein modification by small protein conjugation or removal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.504352937422851", "identifiers": [{"i": "GO:0050900", "l": "leukocyte migration", "d": ["The movement of a leukocyte within or between different tissues and organs of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019305", "l": "dTDP-rhamnose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009665", "l": "plastid inheritance", "d": ["The partitioning of plastids between daughter cells at cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901120", "l": "tobramycin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tobramycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072281", "l": "mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042483", "l": "negative regulation of odontogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900244", "l": "positive regulation of synaptic vesicle endocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901256", "l": "regulation of macrophage colony-stimulating factor production", "d": ["Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046765", "l": "viral budding from nuclear membrane", "d": ["A viral budding that starts with formation of a membrane curvature in the host nuclear membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0018177", "l": "protein uridylylation", "d": ["The addition of phospho-uridine to a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007352", "l": "zygotic specification of dorsal/ventral axis", "d": ["The specification of the dorsal/ventral axis of the embryo, through the products of genes expressed in the zygote."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.959712637402532", "identifiers": [{"i": "GO:0006090", "l": "pyruvate metabolic process", "d": ["The chemical reactions and pathways involving pyruvate, 2-oxopropanoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.450148715325263", "identifiers": [{"i": "GO:2001141", "l": "regulation of RNA biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of RNA biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002453", "l": "peripheral B cell anergy", "d": ["Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in peripheral B cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0031960", "l": "response to corticosteroid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0007492", "l": "endoderm development", "d": ["The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033215", "l": "reductive iron assimilation", "d": ["A process in which iron is solubilized by reduction from Fe3+ to Fe2+ via a cell surface reductase and subsequent transport of the iron across the membrane by iron uptake proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003437", "l": "regulation of cell communication involved in growth plate cartilage morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell communication that contributes to the shaping of the growth plate cartilage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901304", "l": "regulation of spermidine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of spermidine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905932", "l": "positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching", "d": ["Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044079", "l": "modulation by symbiont of host neurotransmitter secretion", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902776", "l": "6-sulfoquinovose(1-) metabolic process", "d": ["The chemical reactions and pathways involving 6-sulfoquinovose(1-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900628", "l": "positive regulation of arugosin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of arugosin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060086", "l": "circadian temperature homeostasis", "d": ["Any homeostatic process in which an organism modulates its internal body temperature at different values with a regularity of approximately 24 hours."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0061014", "l": "positive regulation of mRNA catabolic process", "d": ["Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007473", "l": "wing disc proximal/distal pattern formation", "d": ["The establishment, maintenance and elaboration of the proximal/distal axis of the wing disc, a precursor to the adult wing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903359", "l": "lateral cortical node assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a lateral cortical node."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042846", "l": "glycol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0008218", "l": "bioluminescence", "d": ["The production of light by certain enzyme-catalyzed reactions in cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0048709", "l": "oligodendrocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0008637", "l": "apoptotic mitochondrial changes", "d": ["The morphological and physiological alterations undergone by mitochondria during apoptosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0002287", "l": "alpha-beta T cell activation involved in immune response", "d": ["The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905958", "l": "negative regulation of cellular response to alcohol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060497", "l": "mesenchymal-endodermal cell signaling", "d": ["Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110101", "l": "L-valine transmembrane import into vacuole", "d": ["The directed movement of L-valine into the vacuole across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006824", "l": "cobalt ion transport", "d": ["The directed movement of cobalt (Co) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990264", "l": "peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity", "d": ["Any peptidyl-tyrosine dephosphorylation that is involved in inactivation of protein kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0007634", "l": "optokinetic behavior", "d": ["The behavior of an organism pertaining to movement of the eyes and of objects in the visual field, as in nystagmus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002854", "l": "positive regulation of T cell mediated cytotoxicity directed against tumor cell target", "d": ["Any process that activates or increases the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071502", "l": "cellular response to temperature stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009701", "l": "isoflavonoid phytoalexin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019373", "l": "epoxygenase P450 pathway", "d": ["The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "46.64802194168869", "identifiers": [{"i": "GO:0006952", "l": "defense response", "d": ["Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017187", "l": "peptidyl-glutamic acid carboxylation", "d": ["The gamma-carboxylation of peptidyl-glutamic acid; catalyzed by the vitamin K dependent gamma-glutamyl carboxylase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002489", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060159", "l": "regulation of dopamine receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of a dopamine receptor signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000392", "l": "regulation of lamellipodium morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of lamellipodium morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002595", "l": "regulation of antigen processing and presentation of peptide antigen via MHC class Ib", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0031646", "l": "positive regulation of nervous system process", "d": ["Any process that activates or increases the frequency, rate or extent of a neurophysiological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002086", "l": "diaphragm contraction", "d": ["A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. This process occurs in the diaphragm. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The diaphragm is a striated muscle that is necessary for the process of respiratory gaseous exchange."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090424", "l": "phytochelatin-metal-sulfur complex formation", "d": ["A phytochelatin metabolic process in which a metal and exogenous sulfur are incorporated with phytochelatin to form a complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900106", "l": "positive regulation of hyaluranon cable assembly", "d": ["Any process that activates or increases the frequency, rate or extent of hyaluranon cable assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021817", "l": "nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration", "d": ["The microtubule-mediated movement of the nucleus that is required for the movement of cells along radial glial fibers as a component of the process of cerebral cortex glial-mediated radial cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0035735", "l": "intraciliary transport involved in cilium assembly", "d": ["The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly."]}, {"i": "REACT:R-HSA-5620924.2", "d": []}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000426", "l": "micropexophagy", "d": ["Degradation of a peroxisome by lysosomal microautophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036078", "l": "minus-end specific microtubule depolymerization", "d": ["The removal of tubulin heterodimers from the minus end of a microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0010162", "l": "seed dormancy process", "d": ["A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a seed. Seed dormancy is a suspension of most physiological activity and growth in a seed, including the embryo contained therein, that can be reactivated. It often requires special conditions for reactivation, such as specific temperature, scarification, or leaching of inhibitors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072479", "l": "response to mitotic cell cycle spindle assembly checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of mitotic cell cycle spindle assembly checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0050679", "l": "positive regulation of epithelial cell proliferation", "d": ["Any process that activates or increases the rate or extent of epithelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990069", "l": "stomatal opening", "d": ["The process of opening of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002677", "l": "negative regulation of chronic inflammatory response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050774", "l": "negative regulation of dendrite morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903100", "l": "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:1901016", "l": "regulation of potassium ion transmembrane transporter activity", "d": ["Any process that modulates the frequency, rate or extent of potassium ion transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071864", "l": "positive regulation of cell proliferation in bone marrow", "d": ["A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000893", "l": "cellotriose metabolic process", "d": ["The chemical reactions and pathways involving a cellotriose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035398", "l": "helper T cell enhancement of T cell mediated immune response", "d": ["Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006968", "l": "cellular defense response", "d": ["A defense response that is mediated by cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002107", "l": "generation of mature 3'-end of 5S rRNA generated by RNA polymerase III", "d": ["The removal of extra uridine residues from the 3' end of a 5S pre-rRNA generated by transcription by RNA polymerase III to generate the mature 3'-end."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000213", "l": "positive regulation of glutamate metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of glutamate metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090036", "l": "regulation of protein kinase C signaling", "d": ["Any process that modulates the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046172", "l": "octanol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of octanol, the 8-carbon alcohol with the formula C8H17OH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010020", "l": "chloroplast fission", "d": ["The division of a chloroplast within a cell to form two or more separate chloroplast compartments. This division occurs independently of mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015015", "l": "heparan sulfate proteoglycan biosynthetic process, enzymatic modification", "d": ["The modification, often by sulfation, of sugars incorporated into heparan sulfate after polymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046596", "l": "regulation of viral entry into host cell", "d": ["Any process that modulates the frequency, rate or extent of the viral entry into the host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904786", "l": "negative regulation of asymmetric protein localization involved in cell fate determination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of asymmetric protein localization involved in cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021663", "l": "rhombomere 4 formation", "d": ["The process that gives rise to rhombomere 4. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075132", "l": "disruption of host protein kinase-mediated signal transduction", "d": ["Any process in which a symbiont interferes with protein kinase-mediated signal transduction in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903469", "l": "removal of RNA primer involved in mitotic DNA replication", "d": ["Any DNA replication, removal of RNA primer that is involved in mitotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990579", "l": "peptidyl-serine trans-autophosphorylation", "d": ["The phosphorylation of a peptidyl-serine to form peptidyl-O-phospho-L-serine on an identical protein. For example, phosphorylation by the other kinase within a homodimer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990697", "l": "protein depalmitoleylation", "d": ["The removal of palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), from a lipoprotein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046656", "l": "folic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of folic acid, pteroylglutamic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046008", "l": "regulation of female receptivity, post-mating", "d": ["Any process that modulates the receptiveness of a female to male advances subsequent to mating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0099188", "l": "postsynaptic cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039669", "l": "viral entry into host cell via pilus retraction and membrane fusion", "d": ["The uptake of a virus into a host cell which occurs via retraction of the viral-bound pilus to bring the virus in contact with the host cell membrane, followed by fusion of the bacteriophage membrane with the host outer membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.98780181426379", "identifiers": [{"i": "GO:0043583", "l": "ear development", "d": ["The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.029198101185301", "identifiers": [{"i": "GO:0016050", "l": "vesicle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015765", "l": "methylgalactoside transport", "d": ["The directed movement of methylgalactoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070563", "l": "negative regulation of vitamin D receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the vitamin D receptor signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900003", "l": "regulation of serine-type endopeptidase activity", "d": ["Any process that modulates the frequency, rate or extent of serine-type endopeptidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990554", "l": "mitochondrial 3'-phospho-5'-adenylyl sulfate transmembrane transport", "d": ["The process in which 3'-phospho-5'-adenylyl sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010110", "l": "regulation of photosynthesis, dark reaction", "d": ["Any process that modulates the frequency, rate or extent of photosynthesis dark reaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0045108", "l": "regulation of intermediate filament polymerization or depolymerization", "d": ["Any process that modulates the frequency, rate or extent of the assembly or disassembly of intermediate filaments by the addition or removal of monomers from a filament; this usually occurs through the opposing action of kinases and phosphatases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0014870", "l": "response to muscle inactivity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052062", "l": "induction by symbiont of host phytoalexin production", "d": ["The activation by a symbiont of the production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0051293", "l": "establishment of spindle localization", "d": ["The directed movement of the spindle to a specific location in the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0021594", "l": "rhombomere formation", "d": ["The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0018085", "l": "peptidyl-L-amino acid racemization", "d": ["The process of conversion of a L-amino acid into its enantiomer, the corresponding D-amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060584", "l": "regulation of prostaglandin-endoperoxide synthase activity", "d": ["Any process that modulates the rate, frequency or prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006168", "l": "adenine salvage", "d": ["Any process that generates adenine, 6-aminopurine, from derivatives of it without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046096", "l": "deoxyuridine metabolic process", "d": ["The chemical reactions and pathways involving deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902871", "l": "positive regulation of amacrine cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062090", "l": "positive regulation of taurine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of taurine biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046277", "l": "methylgallate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071257", "l": "cellular response to electrical stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035520", "l": "monoubiquitinated protein deubiquitination", "d": ["The removal of the ubiquitin group from a monoubiquitinated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046827", "l": "positive regulation of protein export from nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071321", "l": "cellular response to cGMP", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0120027", "l": "regulation of osmosensory signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of osmosensory signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046168", "l": "glycerol-3-phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903224", "l": "regulation of endodermal cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of endodermal cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0051555", "l": "flavonol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902147", "l": "regulation of response to cytokinesis checkpoint signaling", "d": ["Any process that modulates the frequency, rate or extent of response to cytokinesis checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001121", "l": "coenzyme gamma-F420-2 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a coenzyme gamma-F420-2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0044346", "l": "fibroblast apoptotic process", "d": ["Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990236", "l": "proteasome core complex import into nucleus", "d": ["The directed movement of the proteasome core complex (AKA core particle (CP)) from the cytoplasm into the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009833", "l": "plant-type primary cell wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of cellulose and pectin-containing cell walls that form adjacent to the middle lamella following cell division and during cell expansion. An example of this is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071798", "l": "response to prostaglandin D", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0045104", "l": "intermediate filament cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019750", "l": "chloroplast localization", "d": ["Any process in which a chloroplast is transported to, and/or maintained in, a specific location within the cell. A chloroplast is a chlorophyll-containing plastid found in cells of algae and higher plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018912", "l": "1,4-dichlorobenzene metabolic process", "d": ["The chemical reactions and pathways involving 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring. It forms white crystals at room temperature and is used as an insecticidal fumigant, particularly in mothballs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0009120", "l": "deoxyribonucleoside metabolic process", "d": ["The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072280", "l": "establishment of planar polarity involved in metanephric nephron morphogenesis", "d": ["Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048133", "l": "male germ-line stem cell asymmetric division", "d": ["The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021551", "l": "central nervous system morphogenesis", "d": ["The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044245", "l": "polysaccharide digestion", "d": ["The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested polysaccharides into components that may be easily absorbed and directed into metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071878", "l": "negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000454", "l": "positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation", "d": ["Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002576", "l": "platelet degranulation", "d": ["The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "38.156842223488013", "identifiers": [{"i": "GO:0035209", "l": "pupal development", "d": ["The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0016119", "l": "carotene metabolic process", "d": ["The chemical reactions and pathways involving carotenes, hydrocarbon carotenoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097745", "l": "mitochondrial tRNA 5'-end processing", "d": ["The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2001098", "l": "tetrasaccharide transport", "d": ["The directed movement of a tetrasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.122953905444049", "identifiers": [{"i": "GO:0042158", "l": "lipoprotein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097215", "l": "negative regulation of lysosomal membrane permeability", "d": ["Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.497615648592138", "identifiers": [{"i": "GO:0009416", "l": "response to light stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.28689886973082", "identifiers": [{"i": "GO:0046486", "l": "glycerolipid metabolic process", "d": ["The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046606", "l": "negative regulation of centrosome cycle", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the centrosome cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019427", "l": "acetyl-CoA biosynthetic process from acetate", "d": ["The chemical reactions and pathways resulting in the formation of acetyl-CoA from acetate, either directly or via acetylphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010199", "l": "organ boundary specification between lateral organs and the meristem", "d": ["The process in which boundaries between lateral organs and the meristem is established and maintained."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046106", "l": "thymine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048617", "l": "embryonic foregut morphogenesis", "d": ["The process in which the anatomical structures of the foregut are generated and organized, during the embryonic phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090182", "l": "regulation of secretion of lysosomal enzymes", "d": ["Any process that modulates the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0051961", "l": "negative regulation of nervous system development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120182", "l": "regulation of focal adhesion disassembly", "d": ["Any process that modulates the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072150", "l": "juxtaglomerulus cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a juxtaglomerulus cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0030587", "l": "sorocarp development", "d": ["The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045818", "l": "negative regulation of glycogen catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032289", "l": "central nervous system myelin formation", "d": ["The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003361", "l": "noradrenergic neuron differentiation involved in brainstem development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036486", "l": "ventral trunk neural crest cell migration", "d": ["The movement of trunk neural crest cells from the neural tube, travelling ventrally through the anterior half of each sclerotome. Trunk neural crest cells that remain in the sclerotome form the dorsal root ganglia containing the sensory neurons. Trunk neural crest cells that continue more ventrally form the sympathetic ganglia, the adrenal medulla, and the nerve clusters surrounding the aorta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0070900", "l": "mitochondrial tRNA modification", "d": ["The covalent alteration of one or more nucleotides within a mitochondrial tRNA molecule to produce a mitochondrial tRNA molecule with a sequence that differs from that coded genetically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003101", "l": "regulation of systemic arterial blood pressure by circulatory epinephrine-norepinephrine", "d": ["The process in which epinephrine-norepinephrine modulate the force with which blood passes through the circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071670", "l": "smooth muscle cell chemotaxis", "d": ["The directed movement of a smooth muscle cell in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0042417", "l": "dopamine metabolic process", "d": ["The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060549", "l": "regulation of fructose 1,6-bisphosphate 1-phosphatase activity", "d": ["Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010796", "l": "regulation of multivesicular body size", "d": ["Any process that modulates the volume of a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071939", "l": "vitamin A import into cell", "d": ["The directed movement of vitamin A from outside of a cell, across the plasma membrane and into the cytosol. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045725", "l": "positive regulation of glycogen biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0070987", "l": "error-free translesion synthesis", "d": ["The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902456", "l": "regulation of stomatal opening", "d": ["Any process that modulates the frequency, rate or extent of stomatal opening."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0034251", "l": "regulation of amide catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051950", "l": "positive regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032897", "l": "negative regulation of viral transcription", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014850", "l": "response to muscle activity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0015746", "l": "citrate transport", "d": ["The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046984", "l": "regulation of hemoglobin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042463", "l": "ocellus photoreceptor cell development", "d": ["Development of photoreceptors, sensory cells that react to the presence of light, found in the ocellus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060375", "l": "regulation of mast cell differentiation", "d": ["Any process that modulates the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901670", "l": "negative regulation of superoxide dismutase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of superoxide dismutase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010673", "l": "positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0022605", "l": "mammalian oogenesis stage", "d": ["A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072240", "l": "metanephric DCT cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the metanephros as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000610", "l": "negative regulation of thyroid hormone generation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone generation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002230", "l": "positive regulation of defense response to virus by host", "d": ["Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034123", "l": "positive regulation of toll-like receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000800", "l": "regulation of endocardial cushion to mesenchymal transition involved in heart valve formation", "d": ["Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:1905517", "l": "macrophage migration", "d": ["The orderly movement of a macrophage from one site to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070378", "l": "positive regulation of ERK5 cascade", "d": ["Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK5 cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010581", "l": "regulation of starch biosynthetic process", "d": ["An process which modulate the frequency, rate or extent of starch biosynthesis, the chemical reactions and pathways resulting in the formation of starch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0051091", "l": "positive regulation of DNA-binding transcription factor activity", "d": ["Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901435", "l": "negative regulation of toluene catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of toluene catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002801", "l": "negative regulation of antifungal peptide secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050971", "l": "detection of mechanical stimulus involved in magnetoreception", "d": ["The series of events involved in magnetoception in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of torque on particles such as magnetite which respond to a magnetic field."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.576969997299727", "identifiers": [{"i": "GO:0032970", "l": "regulation of actin filament-based process", "d": ["Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0090305", "l": "nucleic acid phosphodiester bond hydrolysis", "d": ["The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044489", "l": "negative regulation of voltage-gated sodium channel activity in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904456", "l": "negative regulation of neuronal action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.226136141113301", "identifiers": [{"i": "GO:0006417", "l": "regulation of translation", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0044560", "l": "envenomation resulting in modulation of ion channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an ion channel in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001173", "l": "regulation of histone H2B conserved C-terminal lysine ubiquitination", "d": ["Any process that modulates the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097536", "l": "thymus epithelium morphogenesis", "d": ["The process in which the thymus epithelium is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0000909", "l": "sporocarp development involved in sexual reproduction", "d": ["The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010492", "l": "maintenance of shoot apical meristem identity", "d": ["The process in which an organism retains a population of shoot apical meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905524", "l": "negative regulation of protein autoubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein autoubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048391", "l": "intermediate mesoderm formation", "d": ["The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000750", "l": "negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903176", "l": "regulation of tyrosine 3-monooxygenase activity", "d": ["Any process that modulates the frequency, rate or extent of tyrosine 3-monooxygenase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0051340", "l": "regulation of ligase activity", "d": ["Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055129", "l": "L-proline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-proline, an L-enantiomer of a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0009092", "l": "homoserine metabolic process", "d": ["The chemical reactions and pathways involving homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042059", "l": "negative regulation of epidermal growth factor receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990553", "l": "mitochondrial 5'-adenylyl sulfate transmembrane transport", "d": ["The process in which 5'-adenylyl sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901843", "l": "positive regulation of high voltage-gated calcium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904139", "l": "regulation of microglial cell migration", "d": ["Any process that modulates the frequency, rate or extent of microglial cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042839", "l": "D-glucuronate metabolic process", "d": ["The chemical reactions and pathways involving D-glucuronate, the D-enantiomer of glucuronate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099593", "l": "endocytosed synaptic vesicle to endosome fusion", "d": ["Fusion of an endocytosed synaptic vesicle with an endosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044795", "l": "trans-Golgi network to recycling endosome transport", "d": ["The directed movement of substances, in membrane-bounded vesicles, from the trans-Golgi network to the recycling endosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0001573", "l": "ganglioside metabolic process", "d": ["The chemical reactions and pathways involving ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006404", "l": "RNA import into nucleus", "d": ["The import of RNA from the cytoplasm to the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090111", "l": "regulation of COPII vesicle uncoating", "d": ["Any process that modulates the frequency, rate or extent of COPII vesicle uncoating, the process in which COPII vesicle coat proteins are disassembled, and released."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036496", "l": "regulation of translational initiation by eIF2 alpha dephosphorylation", "d": ["Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the dephosphorylation of eIF2 alpha."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902976", "l": "premeiotic DNA replication preinitiation complex assembly", "d": ["Any DNA replication preinitiation complex assembly that is involved in meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007214", "l": "gamma-aminobutyric acid signaling pathway", "d": ["The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to its receptor on the surface of a target cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075019", "l": "negative regulation of appressorium formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont appressorium formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032529", "l": "follicle cell microvillus organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902242", "l": "copal-8-ol diphosphate(3-) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of copal-8-ol diphosphate(3-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904098", "l": "regulation of protein O-linked glycosylation", "d": ["Any process that modulates the frequency, rate or extent of protein O-linked glycosylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1903438", "l": "positive regulation of mitotic cytokinetic process", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cytokinetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070093", "l": "negative regulation of glucagon secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042439", "l": "ethanolamine-containing compound metabolic process", "d": ["The chemical reactions and pathways involving ethanolamine (2-aminoethanol) and compounds derived from it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900665", "l": "negative regulation of emodin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of emodin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905876", "l": "positive regulation of postsynaptic density organization", "d": ["Any process that activates or increases the frequency, rate or extent of postsynaptic density organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031525", "l": "menthol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061723", "l": "glycophagy", "d": ["The selective autophagy process in which cellular glycogen is delivered to the vacuole and degraded in response to changing cellular conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0071684", "l": "organism emergence from protective structure", "d": ["The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0015802", "l": "basic amino acid transport", "d": ["The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0042710", "l": "biofilm formation", "d": ["A process in which planktonically growing microorganisms grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002485", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035593", "l": "positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region", "d": ["Any process that activates or increases the frequency, rate or extent of the Wnt signaling pathway by the directed movement of a Wnt protein within the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006681", "l": "galactosylceramide metabolic process", "d": ["The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046493", "l": "lipid A metabolic process", "d": ["The chemical reactions and pathways involving lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0090192", "l": "regulation of glomerulus development", "d": ["Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901752", "l": "leukotriene A4 catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of leukotriene A4."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006385", "l": "transcription elongation by RNA polymerase III", "d": ["The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase III promoter by the addition of ribonucleotides catalyzed by RNA polymerase III."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.097524054511453", "identifiers": [{"i": "GO:0006396", "l": "RNA processing", "d": ["Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900868", "l": "sarcinapterin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sarcinapterin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001117", "l": "tetrahydromethanopterin metabolic process", "d": ["The chemical reactions and pathways involving a tetrahydromethanopterin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001579", "l": "medium-chain fatty acid transport", "d": ["The directed movement of a medium-chain fatty acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A medium-chain fatty acid is a fatty acid with an aliphatic tail of 6 to 12 carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0032613", "l": "interleukin-10 production", "d": ["The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904734", "l": "positive regulation of electron transfer activity", "d": ["Any process that activates or increases the frequency, rate or extent of electron transfer activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048389", "l": "intermediate mesoderm development", "d": ["The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039548", "l": "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity", "d": ["Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host IRF3 (interferon regulatory factor-3). IRF3 is a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901668", "l": "regulation of superoxide dismutase activity", "d": ["Any process that modulates the frequency, rate or extent of superoxide dismutase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014006", "l": "regulation of microglia differentiation", "d": ["Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902205", "l": "regulation of interleukin-2-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of interleukin-2-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904936", "l": "interneuron migration", "d": ["The orderly movement of an interneuron from one site to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015971", "l": "guanosine tetraphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044761", "l": "negative regulation by symbiont of host cholinergic synaptic transmission", "d": ["Any process in which a symbiont organism negatively regulates cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033335", "l": "anal fin development", "d": ["The process whose specific outcome is the progression of the anal fin over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097309", "l": "cap1 mRNA methylation", "d": ["Methylation of the ribose of the first nucleotide of a 5'-capped mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060339", "l": "negative regulation of type I interferon-mediated signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060860", "l": "regulation of floral organ abscission", "d": ["Any process that modulates the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060437", "l": "lung growth", "d": ["The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902345", "l": "positive regulation of maltose transport", "d": ["Any process that activates or increases the frequency, rate or extent of maltose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002472", "l": "macrophage antigen processing and presentation", "d": ["The process in which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045454", "l": "cell redox homeostasis", "d": ["Any process that maintains the redox environment of a cell or compartment within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0140719", "l": "constitutive heterochromatin formation", "d": ["The compaction of chromatin into a conformation that is refactory to transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032248", "l": "positive regulation of purine nucleoside transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002000", "l": "detection of renal blood flow", "d": ["The process in which the juxtaglomerular cells of the kidneys receive information about the amount of blood flowing through the arterioles and converts the information to a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051394", "l": "regulation of nerve growth factor receptor activity", "d": ["Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031030", "l": "negative regulation of septation initiation signaling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of septation initiation signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000643", "l": "positive regulation of early endosome to late endosome transport", "d": ["Any process that activates or increases the frequency, rate or extent of early endosome to late endosome transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900905", "l": "regulation of hexadecanal metabolic process", "d": ["Any process that modulates the frequency, rate or extent of hexadecanal metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001408", "l": "guanine nucleotide transport", "d": ["The directed movement of guanine nucleotides, GTP, GDP, and/or GMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000830", "l": "positive regulation of parathyroid hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900649", "l": "regulation of dehydroaustinol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of dehydroaustinol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006982", "l": "response to lipid hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001955", "l": "blood vessel maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010391", "l": "glucomannan metabolic process", "d": ["The chemical reactions and pathways involving glucomannan, a polysaccharide composed of D-glucose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-glucose as single side-units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0110030", "l": "regulation of G2/MI transition of meiotic cell cycle", "d": ["Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045149", "l": "acetoin metabolic process", "d": ["The chemical reactions and pathways involving acetoin, 3-hydroxy-2-butanone, often as part of a fermentation pathway or for use as a carbon source."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006179", "l": "guanosine salvage", "d": ["Any process that generates guanosine, guanine riboside, from derivatives of it without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000086", "l": "positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048509", "l": "regulation of meristem development", "d": ["Any process that modulates the frequency, rate or extent of meristem development, the biological process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061516", "l": "monocyte proliferation", "d": ["The expansion of a monocyte population by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048696", "l": "regulation of collateral sprouting in absence of injury", "d": ["Any process that modulates the frequency, rate or extent of collateral sprouting in the absence of injury."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001205", "l": "negative regulation of osteoclast development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0043057", "l": "backward locomotion", "d": ["Posterior movement of an organism, e.g. following the direction of the tail of an animal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000432", "l": "positive regulation of transcription from RNA polymerase II promoter by glucose", "d": ["Any process involving glucose that activates or increases the rate of transcription from an RNA polymerase II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901563", "l": "response to camptothecin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0051647", "l": "nucleus localization", "d": ["Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903646", "l": "positive regulation of chaperone-mediated protein folding", "d": ["Any process that activates or increases the frequency, rate or extent of chaperone-mediated protein folding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010126", "l": "mycothiol metabolic process", "d": ["The chemical reactions and pathways involving mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007347", "l": "regulation of preblastoderm mitotic cell cycle", "d": ["A cell cycle process that modulates the rate or extent of the progression through the preblastoderm mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090060", "l": "regulation of metaxylem development", "d": ["Any process that modulates the frequency, rate, or extent of metaxylem development. Metaxylem development is the process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045324", "l": "late endosome to vacuole transport", "d": ["The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000798", "l": "negative regulation of amniotic stem cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amniotic stem cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018186", "l": "peroxidase-heme linkage", "d": ["The covalent linkage of heme to peroxidase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060682", "l": "primary ureteric bud growth", "d": ["The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901910", "l": "adenosine 5'-(hexahydrogen pentaphosphate) metabolic process", "d": ["The chemical reactions and pathways involving adenosine 5'-(hexahydrogen pentaphosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0045063", "l": "T-helper 1 cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044870", "l": "modulation by host of viral glycoprotein metabolic process", "d": ["A process in which a host organism modulates the frequency, rate or extent of viral glycoprotein metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902220", "l": "positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "d": ["Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0050802", "l": "circadian sleep/wake cycle, sleep", "d": ["The part of the circadian sleep/wake cycle where the organism is asleep."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060266", "l": "negative regulation of respiratory burst involved in inflammatory response", "d": ["Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072104", "l": "glomerular capillary formation", "d": ["The process that gives rise to a glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1904587", "l": "response to glycoprotein", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060848", "l": "endothelial cell fate determination", "d": ["A process involved in cell fate commitment of an endothelial cell. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0019430", "l": "removal of superoxide radicals", "d": ["Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901009", "l": "(S)-scoulerine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (S)-scoulerine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051947", "l": "regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021502", "l": "neural fold elevation formation", "d": ["The process in which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034223", "l": "regulation of ascospore wall chitin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ascospore wall chitin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.000891501185137", "identifiers": [{"i": "GO:0001819", "l": "positive regulation of cytokine production", "d": ["Any process that activates or increases the frequency, rate or extent of production of a cytokine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048822", "l": "enucleate erythrocyte development", "d": ["The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072213", "l": "metanephric capsule development", "d": ["The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900303", "l": "regulation of laminaritriose transport", "d": ["Any process that modulates the frequency, rate or extent of laminaritriose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0007597", "l": "blood coagulation, intrinsic pathway", "d": ["A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044573", "l": "nitrogenase P cluster assembly", "d": ["The biochemical reactions and pathways resulting in the formation of a P-cluster of a nitrogenase, a high-nuclearity, Fe/S-only cluster that can be viewed as two [4Fe-4S] sub-clusters sharing a gamma-6-sulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098775", "l": "curli assembly", "d": ["The process of assembly of curli, extracellular fibers produced by enteric bacteria. This process occurs outside the cell, where it is coupled to secretion across the cell outer membrane via nucleation by elements of the transporter complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0007041", "l": "lysosomal transport", "d": ["The directed movement of substances into, out of or within a lysosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010138", "l": "pyrimidine ribonucleotide salvage", "d": ["The pathway by which pyrimidine bases or pyrimidine ribonucleosides from pyrimidine nucleotide breakdown are converted back to pyrimidine ribonucleotides. The salvage pathway is important where there is no de novo pyrimidine nucleotide biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061884", "l": "regulation of mini excitatory postsynaptic potential", "d": ["Any process that modulates the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0072485", "l": "response to spindle assembly checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of spindle assembly checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905290", "l": "negative regulation of CAMKK-AMPK signaling cascade", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CAMKK-AMPK signaling cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905000", "l": "regulation of membrane repolarization during atrial cardiac muscle cell action potential", "d": ["Any process that modulates the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035021", "l": "negative regulation of Rac protein signal transduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Rac protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140484", "l": "5-aminolevulinic acid import across plasma membrane", "d": ["The directed movement of 5-aminolevulinic acid from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0050898", "l": "nitrile metabolic process", "d": ["The chemical reactions and pathways involving nitriles, an organic compound containing trivalent nitrogen attached to one carbon atom. The nitriles are named with reference to the acids produced by their decomposition; for example, hydrocyanic acid is formic nitrile, and methyl cyanide is acetic nitrile."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007636", "l": "chemosensory jump behavior", "d": ["The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to a chemical substance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0044363", "l": "modulation of potassium channel activity in another organism", "d": ["Any process in which an organism effects a change in the frequency, rate or extent of the activity of a potassium channel in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048896", "l": "lateral line nerve glial cell migration", "d": ["The movement of a glial cell along the axons in a lateral line nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.314728742240533", "identifiers": [{"i": "GO:0010720", "l": "positive regulation of cell development", "d": ["Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140468", "l": "HRI-mediated signaling", "d": ["A series of reactions in which a signal is passed on to downstream proteins within the cell via HRI (also known as EIF2AK1), an intracellular protein kinase that is activated by stress signals, such as heme deficiency, oxidative stress, osmotic shock, mitochondrial dysfunction and heat shock."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0033157", "l": "regulation of intracellular protein transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033189", "l": "response to vitamin A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051131", "l": "chaperone-mediated protein complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000039", "l": "regulation of trichome morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of trichome morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900867", "l": "sarcinapterin metabolic process", "d": ["The chemical reactions and pathways involving sarcinapterin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905880", "l": "negative regulation of oogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018297", "l": "protein-FAD linkage via 1'-(8alpha-FAD)-L-histidine", "d": ["The formation of a protein-FAD linkage via 1'-(8-alpha-FAD)-L-histidine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042045", "l": "epithelial fluid transport", "d": ["The directed movement of fluid across epithelia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003236", "l": "sinus venosus morphogenesis", "d": ["The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000339", "l": "negative regulation of chemokine (C-X-C motif) ligand 1 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070639", "l": "vitamin D2 metabolic process", "d": ["The chemical reactions and pathways involving vitamin D2, (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0010393", "l": "galacturonan metabolic process", "d": ["The chemical reactions and pathways involving galacturonan, a pectin polymer containing a backbone of alpha-(1->4)-linked D-galacturonic acid residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0061026", "l": "cardiac muscle tissue regeneration", "d": ["The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0022401", "l": "negative adaptation of signaling pathway", "d": ["The negative regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0021826", "l": "substrate-independent telencephalic tangential migration", "d": ["The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036334", "l": "epidermal stem cell homeostasis", "d": ["Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901412", "l": "positive regulation of tetrapyrrole biosynthetic process from glutamate", "d": ["Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035999", "l": "tetrahydrofolate interconversion", "d": ["The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0072765", "l": "centromere localization", "d": ["A cellular localization process in which a centromere/kinetochore is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902462", "l": "positive regulation of mesenchymal stem cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046834", "l": "lipid phosphorylation", "d": ["The process of introducing one or more phosphate groups into a lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034124", "l": "regulation of MyD88-dependent toll-like receptor signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072100", "l": "specification of ureteric bud anterior/posterior symmetry", "d": ["The establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.161881760686384", "identifiers": [{"i": "GO:0044782", "l": "cilium organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051492", "l": "regulation of stress fiber assembly", "d": ["Any process that modulates the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0034114", "l": "regulation of heterotypic cell-cell adhesion", "d": ["Any process that modulates the frequency, rate, or extent of heterotypic cell-cell adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000756", "l": "response to pheromone regulating conjugation with mutual genetic exchange", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus regulating the process of conjugation without cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901625", "l": "cellular response to ergosterol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ergosterol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010121", "l": "arginine catabolic process to proline via ornithine", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline, via ornithine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0070665", "l": "positive regulation of leukocyte proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006166", "l": "purine ribonucleoside salvage", "d": ["Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030047", "l": "actin modification", "d": ["Covalent modification of an actin molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903188", "l": "positive regulation of vitellogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of vitellogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990632", "l": "branching involved in submandibular gland morphogenesis", "d": ["The process in which the branching structure of the submandibular gland is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046054", "l": "dGMP metabolic process", "d": ["The chemical reactions and pathways involving dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001140", "l": "positive regulation of phospholipid transport", "d": ["Any process that activates or increases the frequency, rate or extent of phospholipid transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0031137", "l": "regulation of conjugation with cellular fusion", "d": ["Any process that modulates the rate or frequency of conjugation with cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060480", "l": "lung goblet cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904017", "l": "cellular response to Thyroglobulin triiodothyronine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0035304", "l": "regulation of protein dephosphorylation", "d": ["Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905798", "l": "positive regulation of intraciliary anterograde transport", "d": ["Any process that activates or increases the frequency, rate or extent of intraciliary anterograde transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0098877", "l": "neurotransmitter receptor transport to plasma membrane", "d": ["The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000815", "l": "regulation of mRNA stability involved in response to oxidative stress", "d": ["A process of regulation of mRNA stability that is involved in a response to oxidative stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098720", "l": "succinate import across plasma membrane", "d": ["The directed movement of succinate from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032758", "l": "positive regulation of interleukin-9 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-9 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021624", "l": "oculomotor nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "34.490909553736444", "identifiers": [{"i": "GO:0048731", "l": "system development", "d": ["The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090027", "l": "negative regulation of monocyte chemotaxis", "d": ["Any process that decreases the frequency, rate, or extent of monocyte chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903612", "l": "positive regulation of calcium-dependent ATPase activity", "d": ["Any process that activates or increases the frequency, rate or extent of calcium-dependent ATPase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0032370", "l": "positive regulation of lipid transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072716", "l": "response to actinomycin D", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002927", "l": "archaeosine-tRNA biosynthetic process", "d": ["The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034179", "l": "regulation of toll-like receptor 13 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 13 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044555", "l": "negative regulation of heart rate in another organism", "d": ["Any process that stops, prevents or reduces the frequency of heart contraction of another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905901", "l": "positive regulation of smooth muscle tissue development", "d": ["Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.311492862095925", "identifiers": [{"i": "GO:0001654", "l": "eye development", "d": ["The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.927964040871231", "identifiers": [{"i": "GO:0098773", "l": "skin epidermis development", "d": ["The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071500", "l": "cellular response to nitrosative stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000467", "l": "exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 3'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1901385", "l": "regulation of voltage-gated calcium channel activity", "d": ["Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0010644", "l": "cell communication by electrical coupling", "d": ["The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007438", "l": "oenocyte development", "d": ["The process whose specific outcome is the progression of the oenocyte over time, from its formation to the mature structure. The oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901065", "l": "syringal lignin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of syringal lignin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030708", "l": "germarium-derived female germ-line cyst encapsulation", "d": ["Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the germarium. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1901031", "l": "regulation of response to reactive oxygen species", "d": ["Any process that modulates the frequency, rate or extent of response to reactive oxygen species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048903", "l": "anterior lateral line neuromast hair cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032218", "l": "riboflavin transport", "d": ["The directed movement of riboflavin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0098780", "l": "response to mitochondrial depolarisation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to the depolarization of one or more mitochondria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0039588", "l": "suppression by virus of host antigen processing and presentation", "d": ["Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001189", "l": "negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.586422797268227", "identifiers": [{"i": "GO:0045893", "l": "positive regulation of DNA-templated transcription", "d": ["Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0010455", "l": "positive regulation of cell fate commitment", "d": ["Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0110096", "l": "cellular response to aldehyde", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035186", "l": "syncytial blastoderm mitotic cell cycle", "d": ["Mitotic division cycles 10 to 13 of the insect embryo. This is the second phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. The majority of migrating nuclei reach the embryo surface during cycle 10, after which they divide less synchronously than before, and the syncytial blastoderm cycles lengthen progressively."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006707", "l": "cholesterol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046851", "l": "negative regulation of bone remodeling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0046447", "l": "terpenoid indole alkaloid metabolic process", "d": ["The chemical reactions and pathways involving terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0032467", "l": "positive regulation of cytokinesis", "d": ["Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0099129", "l": "cochlear outer hair cell electromotile response", "d": ["A rapid, force generating length change of an outer hair cell in response to electical stimulation. This occurs naturally as during hearing where it serves a source of mechanical amplification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036184", "l": "asperthecin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002815", "l": "biosynthetic process of antibacterial peptides active against Gram-positive bacteria", "d": ["The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-positive bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051309", "l": "female meiosis chromosome separation", "d": ["The process in which paired chromosomes are physically detached from each other during female meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021768", "l": "nucleus accumbens development", "d": ["The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0051516", "l": "regulation of bipolar cell growth", "d": ["Any process that modulates the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031451", "l": "positive regulation of slow-twitch skeletal muscle fiber contraction", "d": ["Any process that activates or increases the frequency, rate or extent of slow-twitch skeletal muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033467", "l": "CMP-keto-3-deoxy-D-manno-octulosonic acid metabolic process", "d": ["The chemical reactions and pathways involving CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007299", "l": "follicle cell of egg chamber-cell adhesion", "d": ["The attachment of a somatic follicle cell to another somatic follicle cell or to its substratum, the germline cells. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043641", "l": "novobiocin metabolic process", "d": ["The chemical reactions and pathways involving novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0110051", "l": "metabolite repair", "d": ["A cellular process that, through single- or multi-step enzymatic reactions, repairs useless or toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045175", "l": "basal protein localization", "d": ["Any process in which a protein is transported to, or maintained in, basal regions of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990394", "l": "cellular response to cell wall damage", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell wall damage. The process begins with detection of the damage and ends with a change in state or activity of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904307", "l": "response to desipramine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0044855", "l": "plasma membrane raft distribution", "d": ["The process that establishes the spatial arrangement of membrane rafts within a plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0070306", "l": "lens fiber cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010931", "l": "macrophage tolerance induction", "d": ["A process involving any mechanism for tolerance induction in macrophages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904750", "l": "negative regulation of protein localization to nucleolus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003244", "l": "radial growth involved in right ventricle morphogenesis", "d": ["The morphogenic growth in which the right ventricle grows along a radial axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0001174", "l": "transcriptional start site selection at RNA polymerase II promoter", "d": ["Any process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010685", "l": "tetracyclic triterpenoid metabolic process", "d": ["The chemical reactions and pathways involving tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000410", "l": "regulation of thymocyte migration", "d": ["Any process that modulates the frequency, rate or extent of thymocyte migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903799", "l": "negative regulation of miRNA processing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0005993", "l": "trehalose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006232", "l": "TDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of TDP, ribosylthymine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902996", "l": "regulation of neurofibrillary tangle assembly", "d": ["Any process that modulates the frequency, rate or extent of neurofibrillary tangle assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0018094", "l": "protein polyglycylation", "d": ["The addition of glycyl units covalently bound to the gamma carboxyl group peptidyl-glutamic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097207", "l": "bud dormancy process", "d": ["A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a bud. Bud dormancy is a suspension of most physiological activity and growth that can be reactivated. It may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. The exit from bud dormancy is marked by the resumed growth of the bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.664775500092716", "identifiers": [{"i": "GO:0050795", "l": "regulation of behavior", "d": ["Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0006469", "l": "negative regulation of protein kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002302", "l": "CD8-positive, alpha-beta T cell differentiation involved in immune response", "d": ["The process in which an antigenically naive CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072130", "l": "renal capsule specification", "d": ["The regionalization process in which the identity of the renal capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008346", "l": "larval walking behavior", "d": ["The behavior of a larval organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015686", "l": "ferric triacetylfusarinine C import into cell", "d": ["The directed movement of ferric triacetylfusarinine C into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902889", "l": "protein localization to spindle microtubule", "d": ["A process in which a protein is transported to, or maintained in, a location within a spindle microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0071636", "l": "positive regulation of transforming growth factor beta production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061862", "l": "cellular response to differentiation-inducing factor 2", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060215", "l": "primitive hemopoiesis", "d": ["A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904397", "l": "negative regulation of neuromuscular junction development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904312", "l": "cellular response to gold(3+)", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0050989", "l": "N-terminal protein amino acid carboxylation", "d": ["The carboxylation of the N-terminal amino acid of proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0045910", "l": "negative regulation of DNA recombination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:1902407", "l": "assembly of actomyosin apparatus involved in mitotic cytokinesis", "d": ["Any assembly of mitotic cytokinetic actomyosin apparatus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070103", "l": "regulation of interleukin-6-mediated signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of an interleukin-6-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0036296", "l": "response to increased oxygen levels", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048355", "l": "root cap mucilage biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mucilage that occur in the root cap; mucilage is normally synthesized during root growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0045621", "l": "positive regulation of lymphocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018416", "l": "nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide", "d": ["The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0002761", "l": "regulation of myeloid leukocyte differentiation", "d": ["Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.693601310289957", "identifiers": [{"i": "GO:0015844", "l": "monoamine transport", "d": ["The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031393", "l": "negative regulation of prostaglandin biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0036214", "l": "contractile ring localization", "d": ["The process in which a contractile ring is positioned or maintained in a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019312", "l": "L-sorbose metabolic process", "d": ["The chemical reactions and pathways involving sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097579", "l": "extracellular sequestering of copper ion", "d": ["The process of binding or confining copper ions in an extracellular area such that they are separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990882", "l": "rRNA acetylation", "d": ["The modification of rRNA structure by addition of an acetyl group to rRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.134834654920184", "identifiers": [{"i": "GO:0034764", "l": "positive regulation of transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000482", "l": "maturation of 5S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071282", "l": "cellular response to iron(II) ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006146", "l": "adenine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of adenine, 6-aminopurine, one of the 5 main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060373", "l": "regulation of ventricular cardiac muscle cell membrane depolarization", "d": ["Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a ventricular cardiomyocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0050670", "l": "regulation of lymphocyte proliferation", "d": ["Any process that modulates the frequency, rate or extent of lymphocyte proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070452", "l": "positive regulation of ergosterol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000718", "l": "regulation of maintenance of mitotic sister chromatid cohesion, centromeric", "d": ["Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0016104", "l": "triterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of triterpenoid compounds, terpenoids with six isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905246", "l": "negative regulation of aspartic-type peptidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type peptidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003328", "l": "pancreatic D cell fate commitment", "d": ["The commitment of a cell to a pancreatic D cell fate and its capacity to differentiate into a pancreatic D cell. A delta cell is a cell of the pancreas that produces somatostatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.990900157612501", "identifiers": [{"i": "GO:0006275", "l": "regulation of DNA replication", "d": ["Any process that modulates the frequency, rate or extent of DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0052039", "l": "perturbation by symbiont of host cytoskeleton", "d": ["The process in which an organism effects a change that impairs the structure or function of the host cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022034", "l": "rhombomere cell proliferation", "d": ["The multiplication or reproduction of rhombomere cells, resulting in the expansion of the cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0061246", "l": "establishment or maintenance of bipolar cell polarity regulating cell shape", "d": ["Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.432445482536949", "identifiers": [{"i": "GO:0048562", "l": "embryonic organ morphogenesis", "d": ["Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019836", "l": "hemolysis by symbiont of host erythrocytes", "d": ["The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in the host organism by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019681", "l": "acetyl-CoA assimilation pathway", "d": ["The pathways by which acetyl-CoA is processed and converted into alpha-ketoglutarate (2-oxoglutarate); methanogenic archaea use these pathways to assimilate acetyl-CoA into the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060861", "l": "positive regulation of floral organ abscission", "d": ["Any process that increases the rate, frequency, or extent of floral organ shedding, the controlled shedding of floral organs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0001979", "l": "regulation of systemic arterial blood pressure by chemoreceptor signaling", "d": ["The process that modulates blood pressure by the action of chemoreceptors found in the carotid and aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007060", "l": "male meiosis chromosome segregation", "d": ["The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0032095", "l": "regulation of response to food", "d": ["Any process that modulates the frequency, rate or extent of a response to a food stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905845", "l": "positive regulation of cellular response to gamma radiation", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to gamma radiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120094", "l": "negative regulation of peptidyl-lysine crotonylation", "d": ["Any process that stops or reduces the rate of crotonylation of a lysine residue in a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.980302069293842", "identifiers": [{"i": "GO:0006997", "l": "nucleus organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062134", "l": "positive regulation of L-glutamine biosynthetic process", "d": ["Any process that starts, increases the frequency, rate or extent of L-glutamine biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097185", "l": "cellular response to azide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990962", "l": "xenobiotic transport across blood-brain barrier", "d": ["The directed movement of a xenobiotic through the blood-brain barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006122", "l": "mitochondrial electron transport, ubiquinol to cytochrome c", "d": ["The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099152", "l": "regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901208", "l": "negative regulation of heart looping", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of heart looping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.27567501185726", "identifiers": [{"i": "GO:0033013", "l": "tetrapyrrole metabolic process", "d": ["The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090349", "l": "negative regulation of cellular organohalogen metabolic process", "d": ["Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900564", "l": "chanoclavine-I metabolic process", "d": ["The chemical reactions and pathways involving chanoclavine-I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051465", "l": "negative regulation of corticotropin-releasing hormone secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072113", "l": "head kidney development", "d": ["The process whose specific outcome is the progression of the head kidney over time, from its formation to the mature structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061414", "l": "positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source", "d": ["A transcription regulation process in which the presence of a nonfermentable carbon source leads to an increase of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902934", "l": "isopentenol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isopentenol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0002823", "l": "negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901939", "l": "(-)-exo-alpha-bergamotene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (-)-exo-alpha-bergamotene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042893", "l": "polymyxin transport", "d": ["The directed movement of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0051205", "l": "protein insertion into membrane", "d": ["The process that results in the incorporation of a protein into a biological membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000452", "l": "snoRNA guided rRNA 2'-O-methylation", "d": ["The posttranscriptional addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of methylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044498", "l": "envenomation resulting in modulation of blood pressure in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the force with which blood travels through the circulatory system of the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060426", "l": "lung vasculature development", "d": ["The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035155", "l": "negative regulation of terminal cell fate specification, open tracheal system", "d": ["Any process that restricts, stops or prevents a cell from adopting a terminal cell fate in an open tracheal system. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072335", "l": "regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation", "d": ["Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019490", "l": "2-aminobenzenesulfonate desulfonation", "d": ["The removal of the sulfonate group from 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000647", "l": "negative regulation of stem cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051901", "l": "positive regulation of mitochondrial depolarization", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060712", "l": "spongiotrophoblast layer development", "d": ["The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043117", "l": "positive regulation of vascular permeability", "d": ["Any process that increases the extent to which blood vessels can be pervaded by fluid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0001975", "l": "response to amphetamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060265", "l": "positive regulation of respiratory burst involved in inflammatory response", "d": ["Any process that increases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051586", "l": "positive regulation of dopamine uptake involved in synaptic transmission", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of dopamine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010785", "l": "clathrin coating of Golgi vesicle, plasma membrane to endosome targeting", "d": ["The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the plasma membrane to the endosome, forming a vesicle coat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048082", "l": "regulation of adult chitin-containing cuticle pigmentation", "d": ["Any process that modulates the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:1903466", "l": "regulation of mitotic DNA replication initiation", "d": ["Any process that modulates the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0030318", "l": "melanocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a melanocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901951", "l": "regulation of anterograde dense core granule transport", "d": ["Any process that modulates the frequency, rate or extent of anterograde dense core granule transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0042773", "l": "ATP synthesis coupled electron transport", "d": ["The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010352", "l": "lithium ion export across the plasma membrane", "d": ["The directed movement of lithium ion out of a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990185", "l": "regulation of lymphatic vascular permeability", "d": ["Any process that modulates the extent to which lymphatic vessels can be pervaded by fluid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060451", "l": "negative regulation of hindgut contraction", "d": ["Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035943", "l": "estrone secretion", "d": ["The regulated release of estrone into the circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006426", "l": "glycyl-tRNA aminoacylation", "d": ["The process of coupling glycine to glycyl-tRNA, catalyzed by glycyl-tRNA synthetase. The glycyll-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a glycine-accepting tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051482", "l": "positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway", "d": ["Any process that increases the concentration of calcium ions in the cytosol that occurs as part of a PLC-activating G protein-coupled receptor signaling pathway. G-protein-activated PLC hydrolyses phosphatidylinositol-bisphosphate (PIP2) to release diacylglycerol (DAG) and inositol trisphosphate (IP3). IP3 then binds to calcium release channels in the endoplasmic reticulum (ER) to trigger calcium ion release into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001198", "l": "regulation of dendritic cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of dendritic cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042862", "l": "achromobactin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of achromobactin, a citrate siderophore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901554", "l": "response to paracetamol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paracetamol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050965", "l": "detection of temperature stimulus involved in sensory perception of pain", "d": ["The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.825466069370655", "identifiers": [{"i": "GO:0000910", "l": "cytokinesis", "d": ["The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120218", "l": "host interaction involved in quorum sensing", "d": ["A quorum sensing process that is modulated by some interaction with a host cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030328", "l": "prenylcysteine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061261", "l": "mesenchymal to epithelial transition involved in mesonephros morphogenesis", "d": ["A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905277", "l": "negative regulation of epithelial tube formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903017", "l": "positive regulation of exo-alpha-sialidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of exo-alpha-sialidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0080026", "l": "response to indolebutyric acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006712", "l": "mineralocorticoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015773", "l": "raffinose transport", "d": ["The directed movement of raffinose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0014819", "l": "regulation of skeletal muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033140", "l": "negative regulation of peptidyl-serine phosphorylation of STAT protein", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0039503", "l": "suppression by virus of host innate immune response", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904645", "l": "response to amyloid-beta", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018272", "l": "protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine", "d": ["The modification of peptidyl-lysine to form N6-pyridoxal phosphate-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061276", "l": "mesonephric proximal tubule morphogenesis", "d": ["The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.535509353118186", "identifiers": [{"i": "GO:0061982", "l": "meiosis I cell cycle process", "d": ["A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042444", "l": "phenylethylamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905258", "l": "regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042856", "l": "eugenol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034096", "l": "positive regulation of maintenance of meiotic sister chromatid cohesion", "d": ["Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006407", "l": "rRNA export from nucleus", "d": ["The directed movement of rRNA from the nucleus to the cytoplasm; the rRNA is usually in the form of ribonucleoproteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000352", "l": "negative regulation of endothelial cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1990668", "l": "vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane", "d": ["The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane of the ERGIC. This can involve anterograde or retrograde transport vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.712091546727706", "identifiers": [{"i": "GO:0009886", "l": "post-embryonic animal morphogenesis", "d": ["The process, occurring after animal embryonic development, by which anatomical structures are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070605", "l": "regulation of (1->3)-alpha-glucan metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021643", "l": "vagus nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045667", "l": "regulation of osteoblast differentiation", "d": ["Any process that modulates the frequency, rate or extent of osteoblast differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003242", "l": "cardiac chamber ballooning", "d": ["The morphogenic growth in which the chambers of the heart expand in size, contributing to their shaping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0021995", "l": "neuropore closure", "d": ["The process of joining together the neural folds at either end of the neural tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035508", "l": "positive regulation of myosin-light-chain-phosphatase activity", "d": ["Any process that activates or increases the frequency, rate or extent of myosin-light-chain-phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098937", "l": "anterograde dendritic transport", "d": ["The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048764", "l": "trichoblast maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a trichoblast cell to attain its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018336", "l": "peptidyl-tyrosine hydroxylation", "d": ["The hydroxylation of peptidyl-tyrosine to form peptidyl-dihydroxyphenylalanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062034", "l": "L-pipecolic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-pipecolic acid, a metabolite of lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048309", "l": "endoplasmic reticulum inheritance", "d": ["The partitioning of endoplasmic reticulum between daughter cells at cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034625", "l": "fatty acid elongation, monounsaturated fatty acid", "d": ["Elongation of a fatty acid chain into which one C-C double bond has been introduced."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045915", "l": "positive regulation of catecholamine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.062476272212777", "identifiers": [{"i": "GO:0042698", "l": "ovulation cycle", "d": ["The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006734", "l": "NADH metabolic process", "d": ["The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030214", "l": "hyaluronan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2001237", "l": "negative regulation of extrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006013", "l": "mannose metabolic process", "d": ["The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010739", "l": "positive regulation of protein kinase A signaling", "d": ["Any process that increases the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071304", "l": "cellular response to vitamin B6", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903851", "l": "negative regulation of cristae formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cristae formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030539", "l": "male genitalia development", "d": ["The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035009", "l": "negative regulation of melanization defense response", "d": ["Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "50.878313202434541", "identifiers": [{"i": "GO:0008104", "l": "protein localization", "d": ["Any process in which a protein is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060138", "l": "fetal process involved in parturition", "d": ["A reproductive process occurring in the embryo that results in birth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0072098", "l": "anterior/posterior pattern specification involved in kidney development", "d": ["The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071891", "l": "N-terminal peptidyl-proline dimethylation involved in translation", "d": ["An N-terminal peptidyl-proline dimethylation process that contributes to translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904842", "l": "response to nitroglycerin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019513", "l": "lactose catabolic process, using glucoside 3-dehydrogenase", "d": ["The chemical reactions and pathways resulting in the breakdown of lactose, catalyzed by the enzyme glucoside 3-dehydrogenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060983", "l": "epicardium-derived cardiac vascular smooth muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell derived from the epicardium acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051659", "l": "maintenance of mitochondrion location", "d": ["Any process in which a mitochondrion is maintained in a specific location within a cell and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000914", "l": "phragmoplast assembly", "d": ["The formation of a structure composed of actin, myosin, and associated proteins that will function in cytokinesis in cells that perform cytokinesis by cell plate formation. The structure usually contains antiparallel microtubules and membrane (often visible as vesicles)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060904", "l": "regulation of protein folding in endoplasmic reticulum", "d": ["Any process that modulates the rate, frequency or extent of the protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075002", "l": "adhesion of symbiont germination tube to host", "d": ["The attachment of a germination tube of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060030", "l": "dorsal convergence", "d": ["The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036447", "l": "cellular response to sugar-phosphate stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of sugar-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.050408934017838", "identifiers": [{"i": "GO:0071407", "l": "cellular response to organic cyclic compound", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900708", "l": "negative regulation of tensidol A biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tensidol A biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007633", "l": "pattern orientation", "d": ["The actions or reactions of an individual in response to the orientation of a visual pattern. This is exemplified by some classes of insects which are able to detect and learn the orientation of a set of stripes and subsequently behaviorally discriminate between horizontal, vertical or 45 degree stripes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070391", "l": "response to lipoteichoic acid", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018891", "l": "cyclohexanol metabolic process", "d": ["The chemical reactions and pathways involving cyclohexanol, the monohydroxy derivative of cyclohexane. It is used as a solvent and blending agent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900288", "l": "regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process", "d": ["Any process that modulates the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0032042", "l": "mitochondrial DNA metabolic process", "d": ["The chemical reactions and pathways involving mitochondrial DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045039", "l": "protein insertion into mitochondrial inner membrane", "d": ["The processes mediating the insertion of proteins into the mitochondrial inner membrane. Mitochondrial inner membrane proteins can get inserted from the cytosol, by crossing the outer membrane and being guided by an inner membrane translocase complex into their final destination in the inner membrane. Some proteins present in the intermembrane space can get inserted into the inner mitochondrial membrane. Finally, some proteins are inserted into the inner membrane from the matrix side of the membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900975", "l": "negative regulation of tatiopterin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034173", "l": "positive regulation of toll-like receptor 11 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 11 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036011", "l": "imaginal disc-derived leg segmentation", "d": ["Division of an imaginal disc-derived leg into a series of semi-repetitive parts or segments. The Drosophila leg, for example, has nine segments, each separated from the next by a flexible joint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072432", "l": "response to G1 DNA damage checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of G1/S transition DNA damage checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0009690", "l": "cytokinin metabolic process", "d": ["The chemical reactions and pathways involving cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0039535", "l": "regulation of RIG-I signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the RIG-I signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046337", "l": "phosphatidylethanolamine metabolic process", "d": ["The chemical reactions and pathways involving phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. It is a major structural phospholipid in mammalian systems. It tends to be more abundant than phosphatidylcholine in the internal membranes of the cell and is an abundant component of prokaryotic membranes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110075", "l": "regulation of ferroptosis", "d": ["Any process that modulates the frequency, rate or extent of ferroptosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0040037", "l": "negative regulation of fibroblast growth factor receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060483", "l": "lobar bronchus mesenchyme development", "d": ["The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035492", "l": "negative regulation of leukotriene production involved in inflammatory response", "d": ["Any process that decreases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120174", "l": "stress-induced homeostatically regulated protein degradation pathway", "d": ["A stress-inducible protein catabolic pathway that promotes protein quality control by accelerating the degradation of misfolded ER membrane and cytosolic proteins, as well as native proteins. The pathway starts with the activation, by stress, of the Nma111p/Ynm3p serine protease, which cleaves the stress-induced hydrophilin Roq1p, resulting in the generation of a Roq1p cleavage product that selectively interacts with Ubr1p, an E3 ubiquitin ligase. Interaction with the Ubr1p type-1 substrate binding site reprograms the substrate specificity of this ubiquitin ligase resulting in the selective proteasome-mediated degradation of misfolded and native proteins. The pathway ends with degradation of the protein by the cytoplasmic proteasome. Currently, NMA111, ROQ1, UBR1, RAD6, and CDC48 are considered to be involved in this quality control pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071729", "l": "beak morphogenesis", "d": ["The process in which the anatomical structures of the beak are generated and organized. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902788", "l": "response to isooctane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000900", "l": "cyclodextrin metabolic process", "d": ["The chemical reactions and pathways involving a cyclodextrin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034447", "l": "very-low-density lipoprotein particle clearance", "d": ["The process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045122", "l": "aflatoxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072761", "l": "cellular response to capsazepine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0043276", "l": "anoikis", "d": ["Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells and the extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032487", "l": "regulation of Rap protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of Rap protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0034306", "l": "regulation of sexual sporulation", "d": ["Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901093", "l": "regulation of protein homotetramerization", "d": ["Any process that modulates the frequency, rate or extent of protein homotetramerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006581", "l": "acetylcholine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050495", "l": "peptidyl-glycyl-phosphatidylethanolamine biosynthetic process from peptidyl-glycine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked phosphatide following hydrolysis of a glycyl-peptide bond, as in the cleavage of arginine from the carboxy-terminal of Apg8 followed by its amidation with phosphatidylethanolamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0051149", "l": "positive regulation of muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990792", "l": "cellular response to glial cell derived neurotrophic factor", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019606", "l": "2-oxobutyrate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033054", "l": "D-glutamate metabolic process", "d": ["The chemical reactions and pathways involving D-glutamate, the D-enantiomer of the amino acid glutamate, i.e. (2R)-2-aminopentanedioic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061885", "l": "positive regulation of mini excitatory postsynaptic potential", "d": ["Any process that increases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003424", "l": "establishment of cell polarity involved in growth plate cartilage chondrocyte division", "d": ["The cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization that results in the directional division of a growth plate cartilage chondrocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001711", "l": "endodermal cell fate commitment", "d": ["The cell differentiation process that results in commitment of a cell to become part of the endoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0033494", "l": "ferulate metabolic process", "d": ["The chemical reactions and pathways involving ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0010514", "l": "induction of conjugation with cellular fusion", "d": ["The process in which a cell initiates conjugation with cellular fusion. Conjugation with cellular fusion is the process that results in the union of cellular and genetic information from compatible mating types."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046924", "l": "peptide cross-linking via 2-(S-L-cysteinyl)-L-phenylalanine", "d": ["The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-L-phenylalanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071259", "l": "cellular response to magnetism", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.468544520863134", "identifiers": [{"i": "GO:0009880", "l": "embryonic pattern specification", "d": ["The process that results in the patterns of cell differentiation that will arise in an embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006478", "l": "peptidyl-tyrosine sulfation", "d": ["The sulfation of peptidyl-tyrosine residues to form peptidyl-O4'-sulfo-L-tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048586", "l": "regulation of long-day photoperiodism, flowering", "d": ["Any process that modulates the frequency, rate or extent of long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046697", "l": "decidualization", "d": ["The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0039014", "l": "cell differentiation involved in pronephros development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061870", "l": "positive regulation of hepatic stellate cell migration", "d": ["Any process that increases the frequency, rate or extent of hepatic stellate cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000941", "l": "positive regulation of plant-type cell wall cellulose catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0071229", "l": "cellular response to acid chemical", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0052170", "l": "suppression by symbiont of host innate immune response", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000749", "l": "positive regulation of rDNA heterochromatin formation", "d": ["Any process that activates or increases the frequency, rate or extent of rDNA heterochromatin formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044209", "l": "AMP salvage", "d": ["The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from derivatives of it (either adenine, ADP or adenosine 3',5'-bisphosphate) without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903012", "l": "positive regulation of bone development", "d": ["Any process that activates or increases the frequency, rate or extent of bone development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048451", "l": "petal formation", "d": ["The process that gives rise to the petal. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902775", "l": "mitochondrial large ribosomal subunit assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a mitochondrial large ribosomal subunit."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009181", "l": "purine ribonucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902817", "l": "negative regulation of protein localization to microtubule", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0035766", "l": "cell chemotaxis to fibroblast growth factor", "d": ["The directed movement of a motile cell in response to the presence of fibroblast growth factor (FGF)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061612", "l": "galactose to glucose-1-phosphate metabolic process", "d": ["The chemical reactions and pathways in which galactose, the aldohexose galacto-hexose, is converted to glucose-1-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905909", "l": "regulation of dauer entry", "d": ["Any process that modulates the frequency, rate or extent of dauer entry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1903539", "l": "protein localization to postsynaptic membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within a postsynaptic membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052543", "l": "callose deposition in cell wall", "d": ["Any process in which callose is transported to, and/or maintained in, the cell wall. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0022038", "l": "corpus callosum development", "d": ["The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0045624", "l": "positive regulation of T-helper cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009959", "l": "negative gravitropism", "d": ["The orientation of plant parts away from gravity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039502", "l": "suppression by virus of host type I interferon-mediated signaling pathway", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type I interferon-mediated signaling in the host organism. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045712", "l": "positive regulation of larval salivary gland boundary specification", "d": ["Any process that activates or increases the frequency, rate or extent of salivary gland determination in a larval organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0007566", "l": "embryo implantation", "d": ["Attachment of the blastocyst to the uterine lining."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048687", "l": "positive regulation of sprouting of injured axon", "d": ["Any process that activates, maintains or increases the rate of sprouting of an injured axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062030", "l": "negative regulation of stress granule assembly", "d": ["Any process that stops or decreases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034269", "l": "discadenine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140500", "l": "regulation of reticulophagy", "d": ["Any process that modulates the frequency, rate or extent of reticulophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1902306", "l": "negative regulation of sodium ion transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070669", "l": "response to interleukin-2", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904989", "l": "positive regulation of endothelial cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075185", "l": "positive regulation of infection cushion formation", "d": ["Any process that activates or increases the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900685", "l": "positive regulation of fumonisin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of fumonisin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097022", "l": "lymphocyte migration into lymph node", "d": ["The movement of a lymphocyte within the lymphatic system into a lymph node, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090296", "l": "regulation of mitochondrial DNA replication", "d": ["Any process that modulates the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904668", "l": "positive regulation of ubiquitin protein ligase activity", "d": ["Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902382", "l": "11-oxo-beta-amyrin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 11-oxo-beta-amyrin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0048165", "l": "fused antrum stage", "d": ["The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903606", "l": "cytochrome c metabolic process", "d": ["The chemical reactions and pathways involving cytochrome c."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0008053", "l": "mitochondrial fusion", "d": ["Merging of two or more mitochondria within a cell to form a single compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000609", "l": "regulation of thyroid hormone generation", "d": ["Any process that modulates the frequency, rate or extent of thyroid hormone generation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.665032558685994", "identifiers": [{"i": "GO:0051246", "l": "regulation of protein metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901427", "l": "response to propan-1-ol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a propan-1-ol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044812", "l": "fermentative hydrogen production", "d": ["The fermentation of organic substances with a net release of hydrogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060517", "l": "epithelial cell proliferation involved in prostatic bud elongation", "d": ["The multiplication of epithelial cells, contributing to the expansion of the primary prostatic bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098959", "l": "retrograde dendritic transport of mitochondrion", "d": ["The directed movement of mitochondria along microtubules in dendrites towards the cell body and away from the postsynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0031038", "l": "myosin II filament organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0042659", "l": "regulation of cell fate specification", "d": ["Any process that mediates the adoption of a specific fate by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042367", "l": "biotin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002402", "l": "B cell tolerance induction in mucosal-associated lymphoid tissue", "d": ["Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by B cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009822", "l": "alkaloid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901257", "l": "negative regulation of macrophage colony-stimulating factor production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:1901569", "l": "fatty acid derivative catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fatty acid derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.139845358389962", "identifiers": [{"i": "GO:0048736", "l": "appendage development", "d": ["The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0097494", "l": "regulation of vesicle size", "d": ["Any process that modulates the size of a vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0044491", "l": "positive regulation of molecular function in another organism", "d": ["Any process that activates or increases the frequency, rate or extent of the function of proteins in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0030307", "l": "positive regulation of cell growth", "d": ["Any process that activates or increases the frequency, rate, extent or direction of cell growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905764", "l": "regulation of protection from non-homologous end joining at telomere", "d": ["Any process that modulates the frequency, rate or extent of protection from non-homologous end joining at telomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035147", "l": "branch fusion, open tracheal system", "d": ["Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003349", "l": "epicardium-derived cardiac endothelial cell differentiation", "d": ["The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0021579", "l": "medulla oblongata morphogenesis", "d": ["The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0075217", "l": "negative regulation of spore encystment on host", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.920089577627991", "identifiers": [{"i": "GO:0050918", "l": "positive chemotaxis", "d": ["The directed movement of a motile cell or organism towards a higher concentration of a chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061450", "l": "trophoblast cell migration", "d": ["Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.738263026760649", "identifiers": [{"i": "GO:0001820", "l": "serotonin secretion", "d": ["The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039593", "l": "suppression by virus of host exit from mitosis", "d": ["Any viral process which decreases the rate or extent of a host cell leaving M phase of the cell cycle. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097298", "l": "regulation of nucleus size", "d": ["Any process that modulates the size of the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010686", "l": "tetracyclic triterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042062", "l": "long-term strengthening of neuromuscular junction", "d": ["Any process that results in an increase in the efficacy of transmission at a neuromuscular synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046897", "l": "N-terminal peptidyl-tyrosine methylation", "d": ["The methylation of the N-terminal tyrosine of proteins to form the derivative N-methyl-L-tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045870", "l": "positive regulation of single stranded viral RNA replication via double stranded DNA intermediate", "d": ["Any process that activates or increases the frequency, rate or extent of retroviral genome replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000245", "l": "negative regulation of FtsZ-dependent cytokinesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Ftsz-dependent cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:1901879", "l": "regulation of protein depolymerization", "d": ["Any process that modulates the frequency, rate or extent of protein depolymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0072578", "l": "neurotransmitter-gated ion channel clustering", "d": ["The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001044", "l": "regulation of integrin-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of integrin-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0090092", "l": "regulation of transmembrane receptor protein serine/threonine kinase signaling pathway", "d": ["Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019460", "l": "glutamine catabolic process to fumarate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamine into other compounds, including fumarate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905837", "l": "cellular response to triterpenoid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001224", "l": "positive regulation of neuron migration", "d": ["Any process that activates or increases the frequency, rate or extent of neuron migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019403", "l": "galactitol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904693", "l": "midbrain morphogenesis", "d": ["The developmental process by which a midbrain is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075282", "l": "negative regulation of uredinium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070184", "l": "mitochondrial tyrosyl-tRNA aminoacylation", "d": ["The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0031167", "l": "rRNA methylation", "d": ["The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900469", "l": "negative regulation of phosphatidylserine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905836", "l": "response to triterpenoid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044862", "l": "protein transport out of plasma membrane raft", "d": ["The directed movement of a protein out of a plasma membrane raft."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019638", "l": "6-hydroxycineole metabolic process", "d": ["The chemical reactions and pathways involving 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018866", "l": "adamantanone metabolic process", "d": ["The chemical reactions and pathways involving adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902962", "l": "regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061257", "l": "mesonephric podocyte development", "d": ["The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900943", "l": "positive regulation of (Z)-nonadeca-1,14-diene biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.586645131546057", "identifiers": [{"i": "GO:0005975", "l": "carbohydrate metabolic process", "d": ["The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110055", "l": "negative regulation of actin filament annealing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072186", "l": "metanephric cap morphogenesis", "d": ["The process in which the anatomical structures of the metanephric cap are generated and organized. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003065", "l": "positive regulation of heart rate by epinephrine", "d": ["The process in which the secretion of epinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0042204", "l": "s-triazine compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042866", "l": "pyruvate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyruvate, 2-oxopropanoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0050848", "l": "regulation of calcium-mediated signaling", "d": ["Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048883", "l": "neuromast primordium migration", "d": ["The migration of a cluster of a relatively undifferentiated cell originating at specific cephalic placodes and depositing proneuromasts along a developing lateral line, from which the neuromasts will develop."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034089", "l": "establishment of meiotic sister chromatid cohesion", "d": ["The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140199", "l": "negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050883", "l": "musculoskeletal movement, spinal reflex action", "d": ["Involuntary movement caused by the application of a stimulus to an organism and a subsequent movement. The signal processing of this movement takes place in the spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904189", "l": "positive regulation of transformation of host cell by virus", "d": ["Any process that activates or increases the frequency, rate or extent of transformation of host cell by virus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0030859", "l": "polarized epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a polarized epithelial cell. The polarized epithelial cell can be any of the cells within an epithelium where the epithelial sheet is oriented with respect to the planar axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0003389", "l": "retrograde extension", "d": ["The progression of a neuronal projection over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002124", "l": "territorial aggressive behavior", "d": ["Aggressive behavior performed in defence of a fixed area against intruders, typically conspecifics."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0006360", "l": "transcription by RNA polymerase I", "d": ["The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010919", "l": "regulation of inositol phosphate biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061837", "l": "neuropeptide processing", "d": ["Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a neuropeptide precursor. Processing leads to the attainment of the full functional capacity of the neuropeptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0043488", "l": "regulation of mRNA stability", "d": ["Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014890", "l": "smooth muscle atrophy", "d": ["A process, occurring in smooth muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032447", "l": "protein urmylation", "d": ["Covalent attachment of the ubiquitin-like protein URM1 to another protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046400", "l": "keto-3-deoxy-D-manno-octulosonic acid metabolic process", "d": ["The chemical reactions and pathways involving keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904561", "l": "cellular response to diphenidol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0052390", "l": "induction by symbiont of host innate immune response", "d": ["The activation by a symbiont of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0019217", "l": "regulation of fatty acid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000077", "l": "negative regulation of type B pancreatic cell development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110136", "l": "protein-RNA complex remodeling", "d": ["The acquisition, loss, or modification of macromolecules within a protein-RNA complex, resulting in the alteration of an existing complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060357", "l": "regulation of leucine import", "d": ["Any process that modulates the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0018175", "l": "protein nucleotidylation", "d": ["The addition of a nucleotide to a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0007564", "l": "regulation of chitin-based cuticle tanning", "d": ["Any process that modulates the frequency, rate or extent of chitin-based cuticular tanning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1901893", "l": "positive regulation of cell septum assembly", "d": ["Any process that activates or increases the frequency, rate or extent of cell septum assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000795", "l": "negative regulation of epithelial cell proliferation involved in lung morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0048382", "l": "mesendoderm development", "d": ["The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0060563", "l": "neuroepithelial cell differentiation", "d": ["The process in which epiblast cells acquire specialized features of neuroepithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0042196", "l": "chlorinated hydrocarbon metabolic process", "d": ["The chemical reactions and pathways involving chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0015959", "l": "diadenosine polyphosphate metabolic process", "d": ["The chemical reactions and pathways involving diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0033083", "l": "regulation of immature T cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of immature T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034972", "l": "histone H3-R26 methylation", "d": ["The modification of histone H3 by addition of a methyl group to arginine at position 26 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072553", "l": "terminal button organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019394", "l": "glucarate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucarate, the anion of glucaric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1990709", "l": "presynaptic active zone organization", "d": ["A process that results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic active zone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060639", "l": "positive regulation of salivary gland formation by mesenchymal-epithelial signaling", "d": ["Any process that induces the formation of the salivary gland field by means of the secretion of a signal by a mesenchymal cell and its reception and interpretation by an epithelial cell resulting in it adopting the identity of a salivary gland bud cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0180010", "l": "co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway", "d": ["Any process involved in transcription termination-coupled 3' processing of RNA polymerase II mRNA transcripts by the 3' end cleavage  and addition of a poly(A) tail. This pathway is required for the maturation of primary protein-encoding transcripts into functional mRNAs that can be exported from the nucleus and translated in the cytoplasm, but is also required for polyadenylation-dependent decay."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042270", "l": "protection from natural killer cell mediated cytotoxicity", "d": ["The process of protecting a cell from natural killer cell mediated cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070136", "l": "beta-1,2-oligomannoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902167", "l": "positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "d": ["Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0007105", "l": "cytokinesis, division site positioning", "d": ["The process in which a contractile ring is positioned in a specific location. This process is critical for both for both symmetric and asymmetric cell divisions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1904555", "l": "L-proline transmembrane transport", "d": ["The directed movement of L-proline across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902155", "l": "regulation of response to G1 DNA damage checkpoint signaling", "d": ["Any process that modulates the frequency, rate or extent of response to G1 DNA damage checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035238", "l": "vitamin A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid. Animals cannot synthesize vitamin A de novo, but form it through oxidative cleavage of carotenoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060802", "l": "epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification", "d": ["Any process that mediates the transfer of information from an epiblast cell to an extraembryonic ectoderm cell that contributes to the specification of the anterior/posterior axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0015909", "l": "long-chain fatty acid transport", "d": ["The directed movement of a long-chain fatty acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.  A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:2000826", "l": "regulation of heart morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of heart morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099179", "l": "regulation of synaptic membrane adhesion", "d": ["Any process that modulates the frequency, rate or extent of adhesion between pre- and post-synaptic membranes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0050806", "l": "positive regulation of synaptic transmission", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061125", "l": "negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone", "d": ["Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072764", "l": "cellular response to reversine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990297", "l": "renal amino acid absorption", "d": ["A renal system process in which amino acids are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0009820", "l": "alkaloid metabolic process", "d": ["The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000962", "l": "positive regulation of cellooligosaccharide metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellooligosaccharide metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046099", "l": "guanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071420", "l": "cellular response to histamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044635", "l": "positive regulation of complement activation, alternative pathway in another organism", "d": ["Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway, in a different organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.062476272212777", "identifiers": [{"i": "GO:0010038", "l": "response to metal ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.024910309174537", "identifiers": [{"i": "GO:0051046", "l": "regulation of secretion", "d": ["Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007387", "l": "anterior compartment pattern formation", "d": ["The process giving rise to specification of cell identity in the anterior compartments of the segmented embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019689", "l": "pyrimidine nucleoside interconversion", "d": ["The chemical reactions and pathways by which a pyrimidine nucleoside is synthesized from another pyrimidine nucleoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051917", "l": "regulation of fibrinolysis", "d": ["Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902747", "l": "negative regulation of lens fiber cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lens fiber cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903028", "l": "positive regulation of opsonization", "d": ["Any process that activates or increases the frequency, rate or extent of opsonization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098004", "l": "virus tail fiber assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a virus tail fiber."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905628", "l": "negative regulation of serotonin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001270", "l": "regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis", "d": ["Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.685364931984026", "identifiers": [{"i": "GO:0098763", "l": "mitotic cell cycle phase", "d": ["One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006848", "l": "pyruvate transport", "d": ["The directed movement of pyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033515", "l": "L-lysine catabolic process using lysine 6-aminotransferase", "d": ["The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including alpha-aminoadipate; in this pathway, L-lysine is converted to 2-aminoadipate-6-semialdehyde by lysine 6-aminotransferase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071731", "l": "response to nitric oxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043705", "l": "cyanophycin metabolic process", "d": ["The chemical reactions and pathways involving cyanophycin, a non-protein, non-ribosomally produced amino acid polymer composed of an aspartic acid backbone and arginine side groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140438", "l": "protein stearoylation", "d": ["The covalent attachment of a stearoyl group to an amino acid in a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0019539", "l": "hydroxymate-containing siderophore biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including hydroxamic acid. Hydroxamate is one of the three major chemical groups incorporated into siderophore structures with catechol and a-hydroxycarboxylate, each having a high selectivity for iron(3+)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061214", "l": "mesonephric smooth muscle tissue development", "d": ["The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009944", "l": "polarity specification of adaxial/abaxial axis", "d": ["The process resulting in the establishment of polarity along the adaxial/abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019711", "l": "peptidyl-beta-carboxyaspartic acid biosynthetic process from peptidyl-aspartic acid", "d": ["The chemical reactions and pathways resulting in the formation of peptidyl-beta-carboxyaspartic acid from other compounds, including peptidyl-aspartic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0101030", "l": "tRNA-guanine transglycosylation", "d": ["The modification of a tRNA anticodon loop by replacing guanine with queuonine. Reaction is tRNA guanine + queuine = tRNA queuine + guanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035022", "l": "positive regulation of Rac protein signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002560", "l": "basophil mediated immunity", "d": ["Any process involved in the carrying out of an immune response by a basophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902815", "l": "N,N'-diacetylchitobiose import", "d": ["The directed movement of N,N'-diacetylchitobiose into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046377", "l": "colanic acid metabolic process", "d": ["The chemical reactions and pathways involving colanic acid, a capsular bacterial polysaccharide composed of glucose, galactose, fucose and glucuronic acid residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900813", "l": "monodictyphenone metabolic process", "d": ["The chemical reactions and pathways involving monodictyphenone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070200", "l": "establishment of protein localization to telomere", "d": ["The directed movement of a protein to a specific location in the telomeric region of a chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.376522386958577", "identifiers": [{"i": "GO:0061024", "l": "membrane organization", "d": ["A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071955", "l": "recycling endosome to Golgi transport", "d": ["The directed movement of substances from recycling endosomes to the Golgi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001953", "l": "negative regulation of cell-matrix adhesion", "d": ["Any process that stops, prevents, or reduces the rate or extent of cell adhesion to the extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099016", "l": "evasion by virus of DNA end degradation", "d": ["A process by which a virus evades and ends degradation of its DNA when free viral-DNA ends are exposed as part of its life-cycle. For example, some bacteriophages encode proteins that bind to free viral DNA ends, protecting them from degradation by host exonucleases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098964", "l": "anterograde dendritic transport of messenger ribonucleoprotein complex", "d": ["The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites towards the postsynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070902", "l": "mitochondrial tRNA pseudouridine synthesis", "d": ["The intramolecular conversion of uridine to pseudouridine in a mitochondrial tRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070655", "l": "mechanosensory epithelium regeneration", "d": ["The regrowth of lost or destroyed mechanosensory epithelia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003112", "l": "positive regulation of heart rate by neuronal epinephrine", "d": ["The process in which the secretion of epinephrine from nerve endings increases the rate of heart muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060662", "l": "salivary gland cavitation", "d": ["The process in which the solid core of salivary epithelium gives rise to the hollow tube of the gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0001576", "l": "globoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031285", "l": "regulation of sorocarp stalk cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0003093", "l": "regulation of glomerular filtration", "d": ["Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010397", "l": "apiogalacturonan metabolic process", "d": ["The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(1->3)-D-apiose) side chains via O-2 or O-3 links."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0048259", "l": "regulation of receptor-mediated endocytosis", "d": ["Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007555", "l": "regulation of ecdysteroid secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of ecdysteroid from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1903504", "l": "regulation of mitotic spindle checkpoint", "d": ["Any process that modulates the frequency, rate or extent of mitotic spindle checkpoint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904756", "l": "negative regulation of gut granule assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gut granule assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010974", "l": "negative regulation of division septum assembly", "d": ["Any process that decreases the frequency, rate or extent of division septum formation. division septum formation is he assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044395", "l": "protein targeting to vacuolar membrane", "d": ["The process of directing proteins towards the vacuolar membrane; usually uses signals contained within the protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0061951", "l": "establishment of protein localization to plasma membrane", "d": ["The directed movement of a protein to a specific location in a plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900356", "l": "positive regulation of methanofuran metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of methanofuran metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.258924354957735", "identifiers": [{"i": "GO:0098609", "l": "cell-cell adhesion", "d": ["The attachment of one cell to another cell via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060466", "l": "activation of meiosis involved in egg activation", "d": ["Any process that starts the inactive process of meiosis in an egg after the egg has been fertilized or physiologically activated. Eggs generally arrest in meiosis and complete the process after activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000275", "l": "regulation of oxidative phosphorylation uncoupler activity", "d": ["Any process that modulates the frequency, rate or extent of oxidative phosphorylation uncoupler activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000260", "l": "regulation of blood coagulation, common pathway", "d": ["Any process that modulates the frequency, rate or extent of blood coagulation, common pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022023", "l": "radial glial cell fate commitment in forebrain", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a radial glial cell in the forebrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007451", "l": "dorsal/ventral lineage restriction, imaginal disc", "d": ["Formation and/or maintenance of a lineage boundary between dorsal and ventral compartments that cells cannot cross, thus separating the populations of cells in each compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140875", "l": "PR-toxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of PR-toxin, a bicyclic sesquiterpene belonging to the eremophilane class and acting as a mycotoxin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0042554", "l": "superoxide anion generation", "d": ["The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901086", "l": "benzylpenicillin metabolic process", "d": ["The chemical reactions and pathways involving benzylpenicillin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000119", "l": "negative regulation of sodium-dependent phosphate transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sodium-dependent phosphate transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033361", "l": "lysine biosynthetic process via diaminopimelate, dehydrogenase pathway", "d": ["The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in a single enzymatic step."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090234", "l": "regulation of kinetochore assembly", "d": ["Any process that modulates the rate, frequency, or extent of kinetochore assembly, the aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901901", "l": "regulation of protein localization to cell division site involved in cytokinesis", "d": ["Any regulation of protein localization to cell division site that is involved in cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002417", "l": "B cell antigen processing and presentation mediated by B cell receptor uptake of antigen", "d": ["B cell antigen processing and presentation which is initiated by uptake of antigen bound to the B cell receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140909", "l": "kinetoplast DNA replication", "d": ["The process of doubling of the number of maxicircles and minicircles and distribution of the progeny into two daughter networks, which are identical to the parent kinetoplast DNA network."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0072497", "l": "mesenchymal stem cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090366", "l": "positive regulation of mRNA modification", "d": ["Any process that increases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060328", "l": "cytoplasmic actin-based contraction involved in forward cell motility", "d": ["The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the front of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0008207", "l": "C21-steroid hormone metabolic process", "d": ["The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0075310", "l": "regulation of sporangium development", "d": ["Any process that modulates the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0050922", "l": "negative regulation of chemotaxis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0044504", "l": "modulation of receptor activity in another organism", "d": ["The process in which an organism effects a change in the activity of a receptor in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019442", "l": "tryptophan catabolic process to acetyl-CoA", "d": ["The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including acetyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900893", "l": "regulation of tridecane metabolic process", "d": ["Any process that modulates the frequency, rate or extent of tridecane metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0030837", "l": "negative regulation of actin filament polymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010497", "l": "plasmodesmata-mediated intercellular transport", "d": ["The movement of substances between cells via plasmodesmata. Plasmodesmata is a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0042454", "l": "ribonucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072206", "l": "metanephric juxtaglomerular apparatus development", "d": ["The process whose specific outcome is the progression of the juxtaglomerular apparatus in the metanephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045434", "l": "negative regulation of female receptivity, post-mating", "d": ["Any process that stops, prevents or reduces the receptiveness of a female to male advances subsequent to mating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045795", "l": "positive regulation of cell volume", "d": ["Any process that increases cell volume."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021827", "l": "postnatal olfactory bulb interneuron migration", "d": ["The migration of olfactory bulb interneuron precursors in the cerebral cortex that occurs after birth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002669", "l": "positive regulation of T cell anergy", "d": ["Any process that activates or increases the frequency, rate, or extent of T cell anergy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000013", "l": "regulation of arginine biosynthetic process via ornithine", "d": ["Any process that modulates the frequency, rate or extent of arginine biosynthetic process via ornithine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042192", "l": "methylmercury biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of methylmercury (MeHg+), a highly toxic organometal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060558", "l": "regulation of calcidiol 1-monooxygenase activity", "d": ["Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042205", "l": "chlorinated hydrocarbon catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0099637", "l": "neurotransmitter receptor transport", "d": ["The directed movement of neurotransmitter receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019626", "l": "short-chain fatty acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a fatty acid with an aliphatic tail of less than 6 carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070689", "l": "L-threonine catabolic process to propionate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound propionate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0097712", "l": "vesicle targeting, trans-Golgi to periciliary membrane compartment", "d": ["The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002482", "l": "antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-independent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036335", "l": "intestinal stem cell homeostasis", "d": ["Any biological process involved in the maintenance of the steady-state number of intestinal stem cells within a population of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036517", "l": "chemoattraction of serotonergic neuron axon", "d": ["The process in which a serotonergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034721", "l": "histone H3-K4 demethylation, trimethyl-H3-K4-specific", "d": ["The modification of histone H3 by the removal of a methyl group from a trimetylated lysine at position 4 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0006030", "l": "chitin metabolic process", "d": ["The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.481503109560144", "identifiers": [{"i": "GO:0048699", "l": "generation of neurons", "d": ["The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0101027", "l": "optical nerve axon regeneration", "d": ["The regrowth of axons of the optical nerve following their loss or damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903766", "l": "positive regulation of potassium ion export across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of potassium ion export across the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048800", "l": "antennal morphogenesis", "d": ["The process in which the anatomical structures of the antenna are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901542", "l": "regulation of ent-pimara-8(14),15-diene biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0042360", "l": "vitamin E metabolic process", "d": ["The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000892", "l": "cellobiose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a cellobiose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071520", "l": "actomyosin contractile ring assembly actin filament bundle convergence", "d": ["A process of actin filament bundle distribution that occurs in the context of assembling an actomyosin contractile ring during cytokinesis, and that results in the compaction of actin filaments into a tight ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061973", "l": "membrane bone morphogenesis", "d": ["The process in which bone which forms deep in the organism are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000933", "l": "regulation of cellotriose metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellotriose metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090057", "l": "root radial pattern formation", "d": ["The radial pattern formation process that results in the formation of the different tissues of the root around its radial axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000372", "l": "negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001173", "l": "DNA-templated transcriptional start site selection", "d": ["Any process involved in the selection of the specific location within the template strand of a DNA-dependent RNA polymerase promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000845", "l": "positive regulation of testosterone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of testosterone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000888", "l": "arabinoxylan-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an arabinoxylan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0017012", "l": "protein-phytochromobilin linkage", "d": ["The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0009259", "l": "ribonucleotide metabolic process", "d": ["The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.287337192553075", "identifiers": [{"i": "GO:0015849", "l": "organic acid transport", "d": ["The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002421", "l": "B cell antigen processing and presentation following pinocytosis", "d": ["B cell antigen processing and presentation which is initiated by uptake of antigen via pinocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.871876592857262", "identifiers": [{"i": "GO:0006144", "l": "purine nucleobase metabolic process", "d": ["The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0070972", "l": "protein localization to endoplasmic reticulum", "d": ["A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0014744", "l": "positive regulation of muscle adaptation", "d": ["Any process that activates or increases the frequency, rate or extent of muscle adaptation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0006038", "l": "cell wall chitin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900419", "l": "regulation of cellular alcohol catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellular alcohol catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046534", "l": "positive regulation of photoreceptor cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075312", "l": "negative regulation of sporangium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0080009", "l": "mRNA methylation", "d": ["The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060729", "l": "intestinal epithelial structure maintenance", "d": ["A tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018916", "l": "nitrobenzene metabolic process", "d": ["The chemical reactions and pathways involving nitrobenzene (nitrobenzol), a derivative of benzene with an NO2 group attached to the ring. It is a yellow aromatic liquid used in perfumery and manufactured in large quantities in the preparation of aniline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0021930", "l": "cerebellar granule cell precursor proliferation", "d": ["The multiplication or reproduction of neuroblasts that will give rise to granule cells. A granule cell is a glutamatergic interneuron found in the cerebellar cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901150", "l": "vistamycin metabolic process", "d": ["The chemical reactions and pathways involving vistamycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070307", "l": "lens fiber cell development", "d": ["The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1900368", "l": "regulation of post-transcriptional gene silencing by regulatory ncRNA", "d": ["Any process that modulates the frequency, rate or extent of post-transcriptional gene silencing by a non-coding RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0099550", "l": "trans-synaptic signaling, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072438", "l": "response to DNA replication checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of DNA replication checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009397", "l": "folic acid-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of folic acid and its derivatives."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060905", "l": "regulation of induction of conjugation upon nitrogen starvation", "d": ["Any process that modulates the frequency of induction of conjugation upon nitrogen starvation, the process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900269", "l": "negative regulation of reverse transcription", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of reverse transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051902", "l": "negative regulation of mitochondrial depolarization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904137", "l": "negative regulation of convergent extension involved in notochord morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in notochord morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904346", "l": "positive regulation of gastric mucosal blood circulation", "d": ["Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0009141", "l": "nucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048768", "l": "root hair cell tip growth", "d": ["Localized growth of a plant root hair tip by extension of the cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032495", "l": "response to muramyl dipeptide", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018032", "l": "protein amidation", "d": ["Addition of an amide group from a glycine to a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.187403162058388", "identifiers": [{"i": "GO:0051983", "l": "regulation of chromosome segregation", "d": ["Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060212", "l": "negative regulation of nuclear-transcribed mRNA poly(A) tail shortening", "d": ["Any process that decreases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140922", "l": "positive regulation of thermomorphogenesis", "d": ["Any process that increases the rate, frequency or extent of thermomorphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140025", "l": "contractile vacuole tethering involved in discharge", "d": ["The initial, indirect interaction between a contractile vacuole membrane and a site of discharge in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903385", "l": "regulation of homophilic cell adhesion", "d": ["Any process that modulates the frequency, rate or extent of homophilic cell adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010902", "l": "positive regulation of very-low-density lipoprotein particle remodeling", "d": ["Any process that increases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006711", "l": "estrogen catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018884", "l": "carbazole metabolic process", "d": ["The chemical reactions and pathways involving carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010052", "l": "guard cell differentiation", "d": ["The process in which a guard mother cell acquires the specialized features of a guard cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0003203", "l": "endocardial cushion morphogenesis", "d": ["The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010979", "l": "regulation of vitamin D 24-hydroxylase activity", "d": ["Any process that modulates the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018296", "l": "protein-FAD linkage via O4'-(8alpha-FAD)-L-tyrosine", "d": ["The formation of a protein-FAD linkage via O4'-(8-alpha-FAD)-L-tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905559", "l": "positive regulation of mitotic nuclear envelope disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036345", "l": "platelet maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0006626", "l": "protein targeting to mitochondrion", "d": ["The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0009692", "l": "ethylene metabolic process", "d": ["The chemical reactions and pathways involving ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045204", "l": "MAPK export from nucleus", "d": ["The directed movement of a MAP kinase from the nucleus to the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046035", "l": "CMP metabolic process", "d": ["The chemical reactions and pathways involving CMP, cytidine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035902", "l": "response to immobilization stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019075", "l": "virus maturation", "d": ["The refolding and structural rearrangements of virion parts to transition from the intermediate virion to the more mature virion. Maturation usually involves proteolysis events and changes in the folding of the virion proteins. Can occur inside the host cell or after release."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0052042", "l": "induction by symbiont of host programmed cell death", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0034381", "l": "plasma lipoprotein particle clearance", "d": ["The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090408", "l": "phloem nitrate loading", "d": ["The process of loading nitrate into the sieve tube or companion cell of the phloem for long distance transport from source to sink."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904547", "l": "regulation of cellular response to glucose starvation", "d": ["Any process that modulates the frequency, rate or extent of cellular response to glucose starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0007194", "l": "negative regulation of adenylate cyclase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0008039", "l": "synaptic target recognition", "d": ["The process in which a neuronal cell in a multicellular organism interprets signals produced by potential target cells, with which it may form synapses."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072216", "l": "positive regulation of metanephros development", "d": ["Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0015729", "l": "oxaloacetate transport", "d": ["The directed movement of oxaloacetate, the anion of oxobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048792", "l": "spontaneous exocytosis of neurotransmitter", "d": ["The release of a neurotransmitter into the synaptic cleft, where the release step is independent of the presence of calcium ions (Ca2+). The neurotransmitter is contained within a membrane-bounded vesicle, and is released by fusion of the vesicle with the presynaptic plasma membrane of a nerve cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003325", "l": "pancreatic PP cell development", "d": ["The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:1904019", "l": "epithelial cell apoptotic process", "d": ["Any apoptotic process in an epithelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905006", "l": "negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000393", "l": "negative regulation of lamellipodium morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061668", "l": "mitochondrial ribosome assembly", "d": ["The aggregation, arrangement and bonding together of the mitochondrial ribosome and of its subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021608", "l": "accessory nerve formation", "d": ["The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0051161", "l": "arabitol metabolic process", "d": ["The chemical reactions and pathways involving arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903541", "l": "regulation of exosomal secretion", "d": ["Any process that modulates the frequency, rate or extent of exosomal secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035041", "l": "sperm DNA decondensation", "d": ["Unwinding of the condensed nuclear chromatin of an inactive male pronucleus after fertilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035425", "l": "autocrine signaling", "d": ["Signaling between cells of the same type. The signal produced by the signaling cell binds to a receptor on, and affects a cell of the same type."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002085", "l": "inhibition of neuroepithelial cell differentiation", "d": ["Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902041", "l": "regulation of extrinsic apoptotic signaling pathway via death domain receptors", "d": ["Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.401762516328844", "identifiers": [{"i": "GO:0045619", "l": "regulation of lymphocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of lymphocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140876", "l": "andrastin A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of andrastin A, a meroterpenoid that exhibits inhibitory activity against ras farnesyltransferase, suggesting that it could have promising antitumor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000172", "l": "regulation of branching morphogenesis of a nerve", "d": ["Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015905", "l": "bicyclomycin transmembrane transport", "d": ["The directed movement of bicyclomycin across a lipid bilayer, from one side of a membrane to the other. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000303", "l": "regulation of ceramide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0072174", "l": "metanephric tubule formation", "d": ["The developmental process pertaining to the initial formation of a metanephric tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035115", "l": "embryonic forelimb morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043520", "l": "regulation of myosin II filament assembly", "d": ["Any process that modulates the frequency, rate or extent of the formation of a bipolar filament composed of myosin II molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061716", "l": "miRNA export from nucleus", "d": ["The directed movement of a processed miRNA from the nucleus to the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0030100", "l": "regulation of endocytosis", "d": ["Any process that modulates the frequency, rate or extent of endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902870", "l": "negative regulation of amacrine cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amacrine cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0018119", "l": "peptidyl-cysteine S-nitrosylation", "d": ["The covalent addition of a nitric oxide (NO) group to the sulphur (S) atom of a cysteine residue in a protein, to form peptidyl-S-nitrosyl-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1905145", "l": "cellular response to acetylcholine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000939", "l": "regulation of plant-type cell wall cellulose catabolic process", "d": ["Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0018344", "l": "protein geranylgeranylation", "d": ["The covalent attachment of a geranylgeranyl group to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140052", "l": "cellular response to oxidised low-density lipoprotein particle stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidized lipoprotein particle stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902917", "l": "positive regulation of mating projection assembly", "d": ["Any process that activates or increases the frequency, rate or extent of mating projection assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902942", "l": "negative regulation of voltage-gated chloride channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated chloride channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903243", "l": "negative regulation of cardiac muscle hypertrophy in response to stress", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle hypertrophy in response to stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070377", "l": "negative regulation of ERK5 cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK5 cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901959", "l": "positive regulation of cutin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of cutin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009938", "l": "negative regulation of gibberellic acid mediated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of gibberellic acid mediated signaling activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0030655", "l": "beta-lactam antibiotic catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042332", "l": "gravitaxis", "d": ["The directed movement of a motile cell or organism in response to gravity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106248", "l": "positive regulation of poly(A)-specific ribonuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of poly(A)-specific ribonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021687", "l": "cerebellar molecular layer morphogenesis", "d": ["The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071719", "l": "sodium-independent leukotriene transport", "d": ["The directed, sodium-independent, movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140885", "l": "suppression by virus of host type III interferon-mediated signaling pathway", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type III interferon-mediated signaling in the host organism. Type III interferon is also known as interferon-lambda."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901340", "l": "negative regulation of store-operated calcium channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090271", "l": "positive regulation of fibroblast growth factor production", "d": ["Any process that increases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042662", "l": "negative regulation of mesodermal cell fate specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0016107", "l": "sesquiterpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sesquiterpenoid compounds, terpenoids with three isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048926", "l": "electrosensory lateral line system development", "d": ["The process whose specific outcome is the progression of the electrosensory lateral line system over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0018335", "l": "protein succinylation", "d": ["The modification of a protein by the addition of a succinyl group (CO-CH2-CH2-CO) to an amino acid residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0032925", "l": "regulation of activin receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034963", "l": "box C/D RNA processing", "d": ["Any process involved in the conversion of a primary box C/D type small RNA transcript into a mature box C/D RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1905806", "l": "regulation of synapse pruning", "d": ["Any process that modulates the frequency, rate or extent of synapse pruning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901779", "l": "pentalenolactone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pentalenolactone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:2000030", "l": "regulation of response to red or far red light", "d": ["Any process that modulates the frequency, rate or extent of response to red or far red light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903852", "l": "positive regulation of cristae formation", "d": ["Any process that activates or increases the frequency, rate or extent of cristae formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006242", "l": "dCTP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dCTP, deoxycytidine triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904753", "l": "negative regulation of vascular associated smooth muscle cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061235", "l": "mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis", "d": ["The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901078", "l": "negative regulation of relaxation of muscle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035889", "l": "otolith tethering", "d": ["The attachment of a developing otolith to the kinocilia of tether cells in the inner ear."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0090382", "l": "phagosome maturation", "d": ["A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061072", "l": "iris morphogenesis", "d": ["The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018944", "l": "tri-n-butyltin metabolic process", "d": ["The chemical reactions and pathways involving tri-n-butyltin, an organometallic compound composed of three butyl chains attached to a tin atom. Tri-n-butyltin is used as an antifouling agent in ship bottom paints and can be toxic to many marine organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.905555711669919", "identifiers": [{"i": "GO:1900673", "l": "olefin metabolic process", "d": ["The chemical reactions and pathways involving olefin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903636", "l": "regulation of protein insertion into mitochondrial outer membrane", "d": ["Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial outer membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002447", "l": "eosinophil mediated immunity", "d": ["Any process involved in the carrying out of an immune response by an eosinophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097303", "l": "lipoprotein biosynthetic process via N-acyl transfer", "d": ["The chemical reactions and pathways by which N-acyl transfer leads to formation of a water-soluble protein-lipid complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044651", "l": "adhesion of symbiont to host epithelial cell", "d": ["The attachment of a symbiont to a host epithelial cell via adhesion molecules, general stickiness etc., either directly or indirectly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0061247", "l": "mesonephric glomerular mesangium development", "d": ["The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.254170199969643", "identifiers": [{"i": "GO:0046394", "l": "carboxylic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0043007", "l": "maintenance of rDNA", "d": ["Any process involved in sustaining the fidelity and copy number of rDNA repeats."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0018158", "l": "protein oxidation", "d": ["The modification of a protein amino acid by oxidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904383", "l": "response to sodium phosphate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000287", "l": "positive regulation of myotome development", "d": ["Any process that activates or increases the frequency, rate or extent of myotome development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051412", "l": "response to corticosterone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046654", "l": "tetrahydrofolate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902109", "l": "negative regulation of mitochondrial membrane permeability involved in apoptotic process", "d": ["Any negative regulation of mitochondrial membrane permeability that is involved in apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019521", "l": "D-gluconate metabolic process", "d": ["The chemical reactions and pathways involving D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0071219", "l": "cellular response to molecule of bacterial origin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0019665", "l": "anaerobic amino acid catabolic process", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids, yielding energy in the form of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071839", "l": "apoptotic process in bone marrow cell", "d": ["The apoptotic process in cells in the bone marrow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070979", "l": "protein K11-linked ubiquitination", "d": ["A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:0036123", "l": "histone H3-K9 dimethylation", "d": ["The modification of histone H3 by addition of two methyl groups to lysine at position 9 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0045116", "l": "protein neddylation", "d": ["Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901429", "l": "negative regulation of syringal lignin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0052709", "l": "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902075", "l": "cellular response to salt", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0007091", "l": "metaphase/anaphase transition of mitotic cell cycle", "d": ["The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039684", "l": "rolling circle single-stranded viral DNA replication", "d": ["A rolling circle viral DNA replication that begins with a single-stranded viral DNA genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002602", "l": "negative regulation of antigen processing and presentation of polysaccharide antigen via MHC class II", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019529", "l": "taurine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106135", "l": "negative regulation of cardiac muscle cell contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.809557073448779", "identifiers": [{"i": "GO:0010556", "l": "regulation of macromolecule biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001130", "l": "methane biosynthetic process from trimethylamine", "d": ["The chemical reactions and pathways resulting in the formation of a methane from a trimethylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033258", "l": "plastid DNA metabolic process", "d": ["The chemical reactions and pathways involving plastid DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002016", "l": "regulation of blood volume by renin-angiotensin", "d": ["The process in which the renin-angiotensin system controls the rate of fluid intake and output into the blood."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090459", "l": "intracellular aspartate homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of aspartate within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0042368", "l": "vitamin D biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010157", "l": "response to chlorate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018139", "l": "peptide cross-linking via L-phenylalanine thiazolecarboxylic acid", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl phenylalanine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060432", "l": "lung pattern specification process", "d": ["Any developmental process that results in the creation of defined areas or spaces within the lung, to which cells respond and eventually are instructed to differentiate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901369", "l": "cyclic 2,3-bisphospho-D-glycerate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyclic 2,3-bisphospho-D-glyceric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018939", "l": "n-octane metabolic process", "d": ["The chemical reactions and pathways involving n-octane, the 8 carbon straight chain alkane used in organic syntheses, calibrations, and azeotropic distillations. It is a common component of gasoline and other petroleum products and the engine fuel antiknocking properties of an isomer of n-octane are used as a comparative standard in the Octane Rating System."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035754", "l": "B cell chemotaxis", "d": ["The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0033241", "l": "regulation of amine catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044740", "l": "negative regulation of sensory perception of pain in another organism", "d": ["A process that negatively regulates the sensory perception of pain in a different organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.685364931984026", "identifiers": [{"i": "GO:0016999", "l": "antibiotic metabolic process", "d": ["The chemical reactions and pathways involving an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019302", "l": "D-ribose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-ribose, (ribo-pentose)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903072", "l": "regulation of death-inducing signaling complex assembly", "d": ["Any process that modulates the frequency, rate or extent of death-inducing signaling complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.078670642974444", "identifiers": [{"i": "GO:0006955", "l": "immune response", "d": ["Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019433", "l": "triglyceride catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061084", "l": "negative regulation of protein refolding", "d": ["Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099040", "l": "ceramide translocation", "d": ["The movement of a ceramide molecule from one leaflet of a membrane bilayer to the opposite leaflet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905166", "l": "negative regulation of lysosomal protein catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0097089", "l": "methyl-branched fatty acid metabolic process", "d": ["The chemical reactions and pathways involving methyl-branched fatty acids, aliphatic monocarboxylic acids with methyl branches on the main chain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900261", "l": "positive regulation of RNA-dependent RNA polymerase activity", "d": ["Any process that activates or increases the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036450", "l": "polyuridylation-dependent decapping of nuclear-transcribed mRNA", "d": ["Cleavage of the 5'-cap of a nuclear-transcribed mRNA that has been modified by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0051602", "l": "response to electrical stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014906", "l": "myotube cell development involved in skeletal muscle regeneration", "d": ["The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140501", "l": "positive regulation of reticulophagy", "d": ["Any process that increases the frequency, rate or extent of reticulophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904572", "l": "negative regulation of mRNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mRNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016113", "l": "polyterpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of polyterpenoid compounds, terpenoids with more than eight isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.481944844857608", "identifiers": [{"i": "GO:0031668", "l": "cellular response to extracellular stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032731", "l": "positive regulation of interleukin-1 beta production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042697", "l": "menopause", "d": ["Cessation of menstruation, occurring in (e.g.) the human female usually around the age of 50."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0042815", "l": "bipolar cell growth", "d": ["The process in which a cell irreversibly increases in size along one axis through simultaneous polarized growth from opposite ends of a cell, resulting in morphogenesis of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.993037294476458", "identifiers": [{"i": "GO:0006974", "l": "DNA damage response", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070624", "l": "negative regulation of thiamine biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035879", "l": "plasma membrane lactate transport", "d": ["The directed movement of lactate across a plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0019377", "l": "glycolipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900520", "l": "positive regulation of response to pullulan", "d": ["Any process that activates or increases the frequency, rate or extent of response to pullulan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035554", "l": "termination of Roundabout signal transduction", "d": ["The signaling process in which signaling from the receptor ROBO is brought to an end, rather than being reversibly modulated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031141", "l": "induction of conjugation upon carbon starvation", "d": ["The process in which a cell initiates conjugation with cellular fusion upon carbon starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009643", "l": "photosynthetic acclimation", "d": ["A response to light intensity in which exposure to medium-intensity light results in increased tolerance to high-intensity light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046211", "l": "(+)-camphor biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (+)-camphor, a bicyclic monoterpene ketone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "36.308197182678732", "identifiers": [{"i": "GO:0009888", "l": "tissue development", "d": ["The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0008052", "l": "sensory organ boundary specification", "d": ["The process in which boundaries between a sensory organ and the surrounding tissue are established and maintained."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0006075", "l": "(1->3)-beta-D-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097535", "l": "lymphoid lineage cell migration into thymus", "d": ["The movement of a lymphoid lineage cell (also called a lymphoid lineage restricted progenitor cell) into the thymus. Lymphoid lineage cells enter and exit the thymus several times as part of this process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034238", "l": "macrophage fusion", "d": ["The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0042074", "l": "cell migration involved in gastrulation", "d": ["The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035047", "l": "centrosomal and pronuclear rotation", "d": ["The rotation of centrosomes and associated pronuclei in one-cell embryos such as those of Caenorhabditis elegans, occurring as a transition between pronuclear migration and pronuclear fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0097240", "l": "chromosome attachment to the nuclear envelope", "d": ["The process in which chromatin is anchored to the nuclear envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0050658", "l": "RNA transport", "d": ["The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046805", "l": "protein-heme linkage via 1'-L-histidine", "d": ["The covalent linkage of heme and a protein via 1'-L-histidine (otherwise known as tau-heme-histidine, tele-heme-histidine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009765", "l": "photosynthesis, light harvesting", "d": ["Absorption and transfer of the energy absorbed from light photons between photosystem reaction centers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060039", "l": "pericardium development", "d": ["The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.482821972649937", "identifiers": [{"i": "GO:0050865", "l": "regulation of cell activation", "d": ["Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080006", "l": "internode patterning", "d": ["Determines the spacing between two shoot nodes. A shoot node is the region of the shoot where the spikelet, flower, floret, branch, bud and/or leaves are attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019576", "l": "aerobic fructose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the presence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044097", "l": "secretion by the type IV secretion system", "d": ["The controlled release of proteins or DNA by a cell, via the type IV secretion system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003043", "l": "vasoconstriction of artery involved in aortic body chemoreceptor response to lowering of systemic arterial blood pressure", "d": ["A process that is triggered by aortic body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901223", "l": "negative regulation of NIK/NF-kappaB signaling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900232", "l": "negative regulation of single-species biofilm formation on inanimate substrate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation on inanimate substrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0009415", "l": "response to water", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0120010", "l": "intermembrane phospholipid transfer", "d": ["The transport of phospholipids between membranes in which a phospholipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070174", "l": "negative regulation of enamel mineralization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032287", "l": "peripheral nervous system myelin maintenance", "d": ["The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900591", "l": "violaceol II metabolic process", "d": ["The chemical reactions and pathways involving violaceol II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0009394", "l": "2'-deoxyribonucleotide metabolic process", "d": ["The chemical reactions and pathways involving a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:2000136", "l": "regulation of cell proliferation involved in heart morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.651613913496419", "identifiers": [{"i": "GO:0032944", "l": "regulation of mononuclear cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of mononuclear cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0042040", "l": "metal incorporation into metallo-molybdopterin complex", "d": ["The incorporation of a metal into a metallo-molybdopterin complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007121", "l": "bipolar cellular bud site selection", "d": ["The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0032070", "l": "regulation of deoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019556", "l": "histidine catabolic process to glutamate and formamide", "d": ["The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formamide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904341", "l": "regulation of colon smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of colon smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061044", "l": "negative regulation of vascular wound healing", "d": ["Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903420", "l": "protein localization to endoplasmic reticulum tubular network", "d": ["A process in which a protein is transported to, or maintained in, a location within an endoplasmic reticulum tubular network."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904876", "l": "negative regulation of DNA ligase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA ligase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0007140", "l": "male meiotic nuclear division", "d": ["A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0007593", "l": "chitin-based cuticle sclerotization", "d": ["The process of hardening of a chitin-based cuticle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021767", "l": "mammillary body development", "d": ["The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036519", "l": "chemorepulsion of serotonergic neuron axon", "d": ["The process in which a serotonergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045457", "l": "ecdysteroid secretion", "d": ["The regulated release of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010829", "l": "negative regulation of glucose transmembrane transport", "d": ["Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905814", "l": "positive regulation of motor neuron axon guidance", "d": ["Any process that activates or increases the frequency, rate or extent of motor neuron axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902263", "l": "apoptotic process involved in embryonic digit morphogenesis", "d": ["Any apoptotic process that is involved in embryonic digit morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.569439710577498", "identifiers": [{"i": "GO:0001709", "l": "cell fate determination", "d": ["The cellular developmental process involved in cell fate commitment that occurs after cell fate specification,  in which a cell is irreversibly committed to a cellular developmental fate which is heritable on cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039009", "l": "rectal diverticulum development", "d": ["The process whose specific outcome is the progression of the rectal diverticulum over time, from its formation to the mature structure. The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010800", "l": "positive regulation of peptidyl-threonine phosphorylation", "d": ["Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0006625", "l": "protein targeting to peroxisome", "d": ["The process of directing proteins towards the peroxisome, usually using signals contained within the protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0036003", "l": "positive regulation of transcription from RNA polymerase II promoter in response to stress", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043453", "l": "alkyne biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071319", "l": "cellular response to benzoic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0019062", "l": "virion attachment to host cell", "d": ["The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006173", "l": "dADP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032381", "l": "negative regulation of intracellular sterol transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905449", "l": "regulation of Fc-gamma receptor signaling pathway involved in phagocytosis", "d": ["Any process that modulates the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0071830", "l": "triglyceride-rich lipoprotein particle clearance", "d": ["The process in which a triglyceride-rich lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0030148", "l": "sphingolipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048356", "l": "root epithelial mucilage biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901609", "l": "negative regulation of vesicle transport along microtubule", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902424", "l": "negative regulation of attachment of mitotic spindle microtubules to kinetochore", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043312", "l": "neutrophil degranulation", "d": ["The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090495", "l": "low-density lipoprotein particle disassembly", "d": ["The disaggregation of a low-density lipoprotein particle into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045051", "l": "protein insertion into ER membrane by internal uncleaved signal-anchor sequence", "d": ["A process of protein insertion into the endoplasmic reticulum (ER) membrane in which signal anchor sequences function as both ER signal sequences and membrane anchor sequences."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990516", "l": "ribonucleotide excision repair", "d": ["The pathway by which a ribonucleotide is removed from DNA and replaced by a deoxyribonucleotide. The ribonucleotide is incised by RNase H2, and further excised by an endonuclease. The resulting 1 nt gap is then repaired by DNA polymerase and DNA ligase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0001794", "l": "type IIa hypersensitivity", "d": ["An inflammatory response resulting in cell death mediated by activation of the classical complement pathway or induction of effector cell phagocytosis or cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043646", "l": "cephalosporin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0099054", "l": "presynapse assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002735", "l": "positive regulation of myeloid dendritic cell cytokine production", "d": ["Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006002", "l": "fructose 6-phosphate metabolic process", "d": ["The chemical reactions and pathways involving fructose 6-phosphate, also known as F6P. The D-enantiomer is an important intermediate in glycolysis, gluconeogenesis, and fructose metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905627", "l": "regulation of serotonin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of serotonin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052034", "l": "effector-mediated suppression of host pattern-triggered immunity", "d": ["A process mediated by a molecule secreted by a symbiont that results in the suppression of the innate immune response of the host organism via recognition of a microbe-associated molecular pattern. The innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0019757", "l": "glycosinolate metabolic process", "d": ["The chemical reactions and pathways involving glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042776", "l": "proton motive force-driven mitochondrial ATP synthesis", "d": ["The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0071166", "l": "ribonucleoprotein complex localization", "d": ["Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106246", "l": "regulation of poly(A)-specific ribonuclease activity", "d": ["Any process that modulates the rate, frequency or extent of the catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042422", "l": "norepinephrine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097175", "l": "1,6-anhydro-N-acetyl-beta-muramic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1,6-anhydro-N-acetylmuramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901708", "l": "(+)-3'-hydroxylarreatricin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (+)-3'-hydroxylarreatricin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120045", "l": "stereocilium maintenance", "d": ["The organization process that preserves a stereocilium in a stable functional or structural state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051066", "l": "dihydrobiopterin metabolic process", "d": ["The chemical reactions and pathways involving a dihydrobiopterin, a reduced pteridine derivative related to folic acid; it acts as an electron carrier in tyrosine biosynthesis and its quinoid form is produced by oxidation of tetrahydrobiopterin in several biological hydroxylation reactions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904825", "l": "protein localization to microtubule plus-end", "d": ["A process in which a protein is transported to, or maintained in, a location at a microtubule plus-end."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0006949", "l": "syncytium formation", "d": ["The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:0008088", "l": "axo-dendritic transport", "d": ["The directed movement of organelles or molecules along microtubules in neuron projections."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031179", "l": "peptide modification", "d": ["The covalent alteration of one or more amino acid residues within a peptide, resulting in a change in the properties of that peptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903598", "l": "positive regulation of gap junction assembly", "d": ["Any process that activates or increases the frequency, rate or extent of gap junction assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1905709", "l": "negative regulation of membrane permeability", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the passage or uptake of molecules by a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070058", "l": "tRNA gene clustering", "d": ["The process in which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. cerevisiae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0048444", "l": "floral organ morphogenesis", "d": ["The process in which the anatomical structures of the floral organ are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.777964009505382", "identifiers": [{"i": "GO:0000375", "l": "RNA splicing, via transesterification reactions", "d": ["Splicing of RNA via a series of two transesterification reactions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1901000", "l": "regulation of response to salt stress", "d": ["Any process that modulates the frequency, rate or extent of response to salt stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090131", "l": "mesenchyme migration", "d": ["The process in which the population of cells that make up a mesenchyme undergo directed movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000743", "l": "negative regulation of anterior head development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anterior head development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0039604", "l": "suppression by virus of host translation", "d": ["Any process in which a virus prevents or reduces the frequency, rate or extent of translation of host mRNA, for example by cleavage of the host mRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000720", "l": "positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric", "d": ["Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120302", "l": "background adaptation", "d": ["Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900196", "l": "regulation of penicillin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of penicillin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901897", "l": "regulation of relaxation of cardiac muscle", "d": ["Any process that modulates the frequency, rate or extent of relaxation of cardiac muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039012", "l": "pronephric sinus development", "d": ["The process whose specific outcome is the progression of the pronephric sinus over time, from its formation to the mature structure. The pronephric sinus is an ill-defined capillary network that lies between the pronephric tubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052652", "l": "cyclic purine nucleotide metabolic process", "d": ["The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue and the base is a purine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.116918913335823", "identifiers": [{"i": "GO:0030534", "l": "adult behavior", "d": ["Behavior in a fully developed and mature organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.905555711669919", "identifiers": [{"i": "GO:0022618", "l": "protein-RNA complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033548", "l": "myo-inositol hexakisphosphate biosynthetic process, lipid-independent", "d": ["The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, by the successively phosphorylation of myo-inositol or an inositol trisphosphate; the inositol trisphosphates that may be used by this pathway are inositol 3,4,5-trisphosphate and inositol 3,4,6trisphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0032291", "l": "axon ensheathment in central nervous system", "d": ["The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045496", "l": "male analia development", "d": ["The process whose specific outcome is the progression of the analia of the male over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009763", "l": "NAD-malic enzyme C4 photosynthesis", "d": ["The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NAD-malic enzyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0032609", "l": "type II interferon production", "d": ["The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070348", "l": "negative regulation of brown fat cell proliferation", "d": ["Any process that stops or decreases the rate or extent of brown fat cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903712", "l": "cysteine transmembrane transport", "d": ["The directed movement of cysteine across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0010883", "l": "regulation of lipid storage", "d": ["Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0160033", "l": "regulation of Toll receptor ligand protein activation cascade", "d": ["Any process that modulates the frequency, rate or extent of the Toll receptor ligand protein activation cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045225", "l": "negative regulation of CD4 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070299", "l": "positive regulation of phosphorelay signal transduction system", "d": ["Any process that activates or increases the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009828", "l": "plant-type cell wall loosening", "d": ["The series of events causing chemical and structural alterations of an existing cellulose and pectin-containing cell wall that results in greater extensibility of the wall. An example of this is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1990166", "l": "protein localization to site of double-strand break", "d": ["Any process in which a protein is transported to, or maintained at, a region of a chromosome at which a DNA double-strand break has occurred."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0042693", "l": "muscle cell fate commitment", "d": ["The process in which the cellular identity of muscle cells is acquired and determined."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.497915322277517", "identifiers": [{"i": "GO:0044238", "l": "primary metabolic process", "d": ["The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0051123", "l": "RNA polymerase II preinitiation complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905138", "l": "positive regulation of viral DNA genome packaging via site-specific sequence recognition", "d": ["Any process that activates or increases the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.116918913335823", "identifiers": [{"i": "GO:0002704", "l": "negative regulation of leukocyte mediated immunity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0044648", "l": "histone H3-K4 dimethylation", "d": ["The modification of histone H3 by addition of two methyl groups to lysine at position 4 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051072", "l": "4,6-pyruvylated galactose residue biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098730", "l": "male germline stem cell symmetric division", "d": ["The symmetric division of a male germline stem cell to produce two male germline stem cells. An example of this is found in mammalian spermatogonial stem cells, some proportion of which divide symmetrically, so amplifying the population. The choice between asymmetric and symmetric division in this case appears to be internal and stochastic."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007545", "l": "processes downstream of sex determination signal", "d": ["The sex determination processes that take place after the initial transmission of the sexual phenotype to specific information pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901282", "l": "fructoselysine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fructoselysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072011", "l": "glomerular endothelium development", "d": ["The process whose specific outcome is the progression of the glomerular endothelium over time, from its formation to the mature structure. The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030495", "l": "bacteriochlorophyll catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021521", "l": "ventral spinal cord interneuron specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036110", "l": "cellular response to inositol starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of inositol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001049", "l": "regulation of tendon cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of tendon cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071918", "l": "urea transmembrane transport", "d": ["The process in which urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002325", "l": "natural killer cell differentiation involved in immune response", "d": ["The process in which a naive natural killer cell acquires the specialized features of an effector natural killer T cell as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901467", "l": "negative regulation of ferulate catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ferulate catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048674", "l": "collateral sprouting of injured axon", "d": ["The process resulting in reformation of a growth cone by the tip of an injured axon, or in collateral sprouting of the axon. Collateral sprouting is the process in which outgrowths develop from the shafts of existing axons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0030582", "l": "reproductive fruiting body development", "d": ["The process whose specific outcome is the progression of a reproductive fruiting body over time, from its formation to the mature structure. A reproductive fruiting body is a multicellular reproductive structure that contains spores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.134834654920184", "identifiers": [{"i": "GO:0007033", "l": "vacuole organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900171", "l": "positive regulation of glucocorticoid mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of glucocorticoid mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0034331", "l": "cell junction maintenance", "d": ["The organization process that preserves a cell junction in a stable functional or structural state. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110041", "l": "regulation of pharynx morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043448", "l": "alkane catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901583", "l": "tetrapeptide import across plasma membrane", "d": ["The directed movement of a tetrapeptide from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019636", "l": "phosphonoacetate metabolic process", "d": ["The chemical reactions and pathways involving phosphonoacetate, C2H4PO5, a substance composed of an acetate and a phosphonic acid residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001924", "l": "regulation of B-1 B cell differentiation", "d": ["Any process that modulates the frequency, rate, or extent of B-1 B cell differentiation. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901040", "l": "negative regulation of peptide antigen transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of peptide antigen transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071905", "l": "protein N-linked glucosylation via asparagine", "d": ["A process of protein N-linked glycosylation via asparagine in which glucose is added to the N4 of asparagine, forming an (S)-2-amino-4-(D-glucopyranosyl)amino-4-oxobutanoic acid residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902899", "l": "fatty acid methyl ester biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fatty acid methyl ester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019742", "l": "pentacyclic triterpenoid metabolic process", "d": ["The chemical reactions and pathways involving pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022031", "l": "telencephalon astrocyte cell migration", "d": ["The orderly movement of an astrocyte cell through the telencephalon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021606", "l": "accessory nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0002251", "l": "organ or tissue specific immune response", "d": ["An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0052094", "l": "formation of haustorium for nutrient acquisition", "d": ["The assembly of a haustorium, a projection from a symbiotic cell or tissue that penetrates the host's tissues for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035318", "l": "imaginal disc-derived wing hair outgrowth", "d": ["Extrusion of a cellular projection from the apical membrane of an epithelial cell in an imaginal disc-derived wing. Outgrowth initiates approximately 35 hours after puparium formation from the distal side of the cell, and at this stage the cellular extension is termed a prehair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.780700721499244", "identifiers": [{"i": "GO:0051607", "l": "defense response to virus", "d": ["Reactions triggered in response to the presence of a virus that act to protect the cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046080", "l": "dUTP metabolic process", "d": ["The chemical reactions and pathways involving dUTP, deoxyuridine (5'-)triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0006284", "l": "base-excision repair", "d": ["In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0060538", "l": "skeletal muscle organ development", "d": ["The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0006525", "l": "arginine metabolic process", "d": ["The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052086", "l": "suppression by symbiont of host B-cell mediated immune response", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903122", "l": "negative regulation of TRAIL-activated apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071405", "l": "cellular response to methanol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099155", "l": "synaptic transmission, noradrenergic", "d": ["The vesicular release of noradrenaline (norepinephrine) a presynapse, across a chemical synapse, the subsequent activation of noradrenaline receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0010004", "l": "gastrulation involving germ band extension", "d": ["A complex and coordinated series of cellular movements, including germ band extension, that occurs at the end of cleavage during embryonic development. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0044839", "l": "cell cycle G2/M phase transition", "d": ["The cell cycle process by which a cell in G2 phase commits to M phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150159", "l": "negative regulation of interleukin-34 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-34 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071393", "l": "cellular response to progesterone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010816", "l": "calcitonin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900316", "l": "negative regulation of maltopentaose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maltopentaose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.790184063220053", "identifiers": [{"i": "GO:0120254", "l": "olefinic compound metabolic process", "d": ["The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006422", "l": "aspartyl-tRNA aminoacylation", "d": ["The process of coupling aspartate to aspartyl-tRNA, catalyzed by aspartyl-tRNA synthetase. The aspartyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an aspartic acid accetping tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060950", "l": "cardiac glial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900947", "l": "regulation of isoprene biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of isoprene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0046605", "l": "regulation of centrosome cycle", "d": ["Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.207992593949683", "identifiers": [{"i": "GO:0001909", "l": "leukocyte mediated cytotoxicity", "d": ["The directed killing of a target cell by a leukocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903547", "l": "regulation of growth hormone activity", "d": ["Any process that modulates the frequency, rate or extent of growth hormone activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905179", "l": "negative regulation of cardiac muscle tissue regeneration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle tissue regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0060923", "l": "cardiac muscle cell fate commitment", "d": ["The commitment of cells to specific cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990793", "l": "substance P secretion, neurotransmission", "d": ["The controlled release of substance P by a cell, in which the substance P acts as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019056", "l": "modulation by virus of host transcription", "d": ["Any process in which a virus modulates the frequency, rate or extent of its host's transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061032", "l": "visceral serous pericardium development", "d": ["The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.783030043623796", "identifiers": [{"i": "GO:0006898", "l": "receptor-mediated endocytosis", "d": ["An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:0002690", "l": "positive regulation of leukocyte chemotaxis", "d": ["Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904058", "l": "positive regulation of sensory perception of pain", "d": ["Any process that activates or increases the frequency, rate or extent of sensory perception of pain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140446", "l": "fumigermin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fumigermin, an alpha-pyrone secondary metabolite found in some species of fungi such as Aspergillus fumigatus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035506", "l": "negative regulation of myosin light chain kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of myosin light chain kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034607", "l": "turning behavior involved in mating", "d": ["The sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900511", "l": "positive regulation of pentose catabolic process to ethanol", "d": ["Any process that activates or increases the frequency, rate or extent of pentose catabolic process to ethanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0070534", "l": "protein K63-linked ubiquitination", "d": ["A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010841", "l": "positive regulation of circadian sleep/wake cycle, wakefulness", "d": ["Any process that increases the frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0001947", "l": "heart looping", "d": ["The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002808", "l": "regulation of antibacterial peptide biosynthetic process", "d": ["Any process that modulates the frequency, rate, or extent of antibacterial peptide biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901222", "l": "regulation of NIK/NF-kappaB signaling", "d": ["Any process that modulates the frequency, rate or extent of NIK/NF-kappaB signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901462", "l": "positive regulation of response to formic acid", "d": ["Any process that activates or increases the frequency, rate or extent of response to formic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090370", "l": "negative regulation of cholesterol efflux", "d": ["Any process that decreases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0035215", "l": "genital disc development", "d": ["Progression of the genital imaginal disc over time, from its initial formation through to its metamorphosis to form the adult terminalia, comprising the entire set of internal and external genitalia and analia. Both sexes of Drosophila have a single genital disc formed from the female and male genital primordia, and the anal primordium. The anal primordium develops in both sexes, forming either male or female analia. However, only one of the genital primordia develops in each sex, forming either the male or the female genitalia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018004", "l": "N-terminal protein formylation", "d": ["The formylation of the N-terminal amino acid of proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901260", "l": "peptidyl-lysine hydroxylation involved in bacterial-type EF-P lysine modification", "d": ["Any peptidyl-lysine hydroxylation that is involved in bacterial-type EF-P lysine modification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031538", "l": "negative regulation of anthocyanin metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.327400668044291", "identifiers": [{"i": "GO:0043935", "l": "sexual sporulation resulting in formation of a cellular spore", "d": ["The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010202", "l": "response to low fluence red light stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Low fluence red light is defined in this case as short pulses of red light followed by darkness, providing a light level of 0.001-0.1 mmol/m2/sec."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002607", "l": "regulation of myeloid dendritic cell antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010609", "l": "mRNA localization resulting in post-transcriptional regulation of gene expression", "d": ["Any process that modulates the frequency, rate or extent of gene expression after the production of a mRNA transcript by its transport into, or maintainance in, a specific location within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.825956045430587", "identifiers": [{"i": "GO:1905952", "l": "regulation of lipid localization", "d": ["Any process that modulates the frequency, rate or extent of lipid localization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903824", "l": "negative regulation of telomere single strand break repair", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomere single strand break repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010820", "l": "positive regulation of T cell chemotaxis", "d": ["Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044742", "l": "envenomation resulting in modulation of sensory perception of pain in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the sensory perception of pain in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "38.098988603728223", "identifiers": [{"i": "GO:0002165", "l": "instar larval or pupal development", "d": ["The process whose specific outcome is the progression of the instar larva or pupa over time, from its formation to the mature structure. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075240", "l": "regulation of zoospore formation", "d": ["Any process that modulates the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000547", "l": "regulation of dendritic cell dendrite assembly", "d": ["Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018303", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0045161", "l": "neuronal ion channel clustering", "d": ["The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1903059", "l": "regulation of protein lipidation", "d": ["Any process that modulates the frequency, rate or extent of protein lipidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.65552684834234", "identifiers": [{"i": "GO:0009593", "l": "detection of chemical stimulus", "d": ["The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.576417257927446", "identifiers": [{"i": "GO:0034655", "l": "nucleobase-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.362525179576039", "identifiers": [{"i": "GO:0008585", "l": "female gonad development", "d": ["The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0002040", "l": "sprouting angiogenesis", "d": ["The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010047", "l": "fruit dehiscence", "d": ["The process leading to the spontaneous opening of the fruit permitting the escape of seeds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001245", "l": "regulation of phosphatidylcholine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylcholine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900786", "l": "naphtho-gamma-pyrone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of naphtho-gamma-pyrone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035116", "l": "embryonic hindlimb morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090708", "l": "specification of plant organ axis polarity", "d": ["The process in which the polarity of a plant organ axis is specified."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010058", "l": "regulation of atrichoblast fate specification", "d": ["Any process that modulates atrichoblast fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002915", "l": "negative regulation of central B cell anergy", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell anergy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010533", "l": "regulation of activation of Janus kinase activity", "d": ["Any process that modulates the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048657", "l": "anther wall tapetum cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an anther cell wall tapetum cell. The tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.362525179576039", "identifiers": [{"i": "GO:0044060", "l": "regulation of endocrine process", "d": ["Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900570", "l": "diorcinol metabolic process", "d": ["The chemical reactions and pathways involving diorcinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014747", "l": "positive regulation of tonic skeletal muscle contraction", "d": ["Any process that activates or increases the frequency, rate or extent of tonic skeletal muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075047", "l": "negative regulation of formation by symbiont of haustorium for nutrient acquisition from host", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903773", "l": "negative regulation of viral budding via host ESCRT complex", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of viral budding via host ESCRT complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900541", "l": "fumonisin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fumonisin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035206", "l": "regulation of hemocyte proliferation", "d": ["Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031322", "l": "ascospore-type prospore-specific spindle pole body remodeling", "d": ["A spindle pole body (SPB) organization process that takes place during the second meiotic division during ascospore formation and results in the structural reorganization of the SPB; includes the recruitment of sporulation-specific proteins to the outer plaque to form the meiotic outer plaque (MOP)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060233", "l": "oenocyte delamination", "d": ["The negative regulation of cell adhesion process in which an oenocyte splits off of an existing epithelial sheet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0018200", "l": "peptidyl-glutamic acid modification", "d": ["The modification of peptidyl-glutamic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018913", "l": "anaerobic ethylbenzene metabolic process", "d": ["The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring, that occur in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0003096", "l": "renal sodium ion transport", "d": ["The directed movement of sodium ions (Na+) by the renal system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905181", "l": "regulation of urease activity", "d": ["Any process that modulates the frequency, rate or extent of urease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051027", "l": "DNA transport", "d": ["The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007311", "l": "maternal specification of dorsal/ventral axis, oocyte, germ-line encoded", "d": ["Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by cells of the germ line. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075130", "l": "modulation by symbiont of host protein kinase-mediated signal transduction", "d": ["Any process in which the symbiont modulates the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019244", "l": "lactate biosynthetic process from pyruvate", "d": ["The chemical reactions and pathways resulting in the formation of lactate from other compounds, including pyruvate."]}, {"i": "REACT:R-HSA-71849.1", "d": []}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140255", "l": "regulation of cellular response to phosphate starvation", "d": ["Any process that modulates the frequency, rate or extent of cellular response to phosphate starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031336", "l": "negative regulation of sulfur amino acid metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071352", "l": "cellular response to interleukin-2", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006393", "l": "termination of mitochondrial transcription", "d": ["A transcription termination process that completes the production of a primary mitochondrial transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035566", "l": "regulation of metanephros size", "d": ["Any process that modulates the size of a metanephric kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044617", "l": "modulation of relaxation of smooth muscle in another organism", "d": ["The process in which an organism effects a change in the relaxation of smooth muscle in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903217", "l": "negative regulation of protein processing involved in protein targeting to mitochondrion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080142", "l": "regulation of salicylic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of salicylic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901544", "l": "positive regulation of ent-pimara-8(14),15-diene biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.980302069293842", "identifiers": [{"i": "GO:0007409", "l": "axonogenesis", "d": ["De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010756", "l": "positive regulation of plasminogen activation", "d": ["Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0014044", "l": "Schwann cell development", "d": ["The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0003031", "l": "detection of carbon dioxide", "d": ["The series of events in which a carbon dioxide stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0006099", "l": "tricarboxylic acid cycle", "d": ["A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051935", "l": "glutamate reuptake", "d": ["The uptake of L-glutamate by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003339", "l": "regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "d": ["Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.967140482697559", "identifiers": [{"i": "GO:0048827", "l": "phyllome development", "d": ["The process whose specific outcome is the progression of a phyllome over time, from its formation to the mature structure. A phyllome is a collective term for all the different types of leaves appearing on plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0030177", "l": "positive regulation of Wnt signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of Wnt signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052321", "l": "negative regulation of phytoalexin metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060898", "l": "eye field cell fate commitment involved in camera-type eye formation", "d": ["The commitment of neurectodermal cells to cells of the eye field and their capacity to differentiate into eye field cells. Eye field cells are neurectodermal cells that will form the optic placode."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000784", "l": "positive regulation of establishment of cell polarity regulating cell shape", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of cell polarity regulating cell shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140746", "l": "siRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of small interfering RNA transcripts (siRNAs)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003117", "l": "regulation of vasoconstriction by circulating norepinephrine", "d": ["Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0052324", "l": "plant-type cell wall cellulose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060101", "l": "negative regulation of phagocytosis, engulfment", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905536", "l": "negative regulation of eukaryotic translation initiation factor 4F complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044838", "l": "cell quiescence", "d": ["A specialized resting state that cells enter in response to cues from the cell's environment. Quiescence is characterized by the absence of cell growth and division, by a reprogramming of global gene expression, and by changes characteristic of the organism and specific cell type. Depending on external conditions, quiescence may persist until cell death or cells may resume cell growth and division. In some cell types or under certain conditions, cellular metabolism may proceed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0003028", "l": "regulation of systemic arterial blood pressure by aortic body chemoreceptor signaling", "d": ["The process that modulates blood pressure by the action of chemoreceptors found in the aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900556", "l": "emericellamide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of emericellamide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002555", "l": "histamine secretion by platelet", "d": ["The regulated release of histamine by a platelet or group of platelets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0098883", "l": "synapse pruning", "d": ["A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022033", "l": "telencephalon microglial cell migration", "d": ["The orderly movement of microglial cells through the telencephalon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.27567501185726", "identifiers": [{"i": "GO:1902600", "l": "proton transmembrane transport", "d": ["The directed movement of a proton across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903765", "l": "negative regulation of potassium ion export across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export across the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901937", "l": "beta-caryophyllene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-caryophyllene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000887", "l": "glucuronoarabinoxylan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a glucuronoarabinoxylan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045456", "l": "ecdysteroid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048661", "l": "positive regulation of smooth muscle cell proliferation", "d": ["Any process that activates or increases the rate or extent of smooth muscle cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035152", "l": "regulation of tube architecture, open tracheal system", "d": ["Ensuring that tracheal cells form and maintain tubular structures with the correct size and shape for their position in the network. This is essential for efficient flow of gases through the tracheal network."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007462", "l": "R1/R6 cell fate commitment", "d": ["The process in which the R1/R6 photoreceptors commit to their cell fate. R1 and R6 are paired photoreceptors which contribute the outer rhabdomeres."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048712", "l": "negative regulation of astrocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048901", "l": "anterior lateral line neuromast development", "d": ["The process whose specific outcome is the progression of the anterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902437", "l": "positive regulation of male mating behavior", "d": ["Any process that activates or increases the frequency, rate or extent of male mating behavior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048202", "l": "clathrin coating of Golgi vesicle", "d": ["The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0051873", "l": "killing by host of symbiont cells", "d": ["Any process mediated by an organism that results in the death of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035648", "l": "circadian mating behavior", "d": ["The fluctuation in mating behavior that occurs over an approximately 24 hour cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014068", "l": "positive regulation of phosphatidylinositol 3-kinase signaling", "d": ["Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001011", "l": "positive regulation of plant-type cell wall cellulose biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0006825", "l": "copper ion transport", "d": ["The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071519", "l": "actomyosin contractile ring actin filament bundle assembly", "d": ["A process of actin filament bundle formation that occurs in the context of assembling an actomyosin contractile ring during cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090664", "l": "response to high population density", "d": ["Any process that results in a change in state or activity of a cell or a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a higher than normal number of multicellular organisms living per unit area."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048650", "l": "caste determination, influence by environmental factors", "d": ["The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental cues. Individuals with distinct developmental fates perform different functions in a colony of social insects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0061644", "l": "protein localization to CENP-A containing chromatin", "d": ["Any process in which a protein is transported to, or maintained at, CENP-A containing chromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075221", "l": "negative regulation of zoospore encystment on host", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021820", "l": "extracellular matrix organization in marginal zone involved in cerebral cortex radial glia guided migration", "d": ["The process that leads to the deposition of extracellular matrix signals in the marginal zone of the developing cerebral cortex. This extracellular matrix controls the movement of migrating cells. In mammals, the matrix is modified by Cajal-Retzius cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902512", "l": "positive regulation of apoptotic DNA fragmentation", "d": ["Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.240943961099731", "identifiers": [{"i": "GO:0048870", "l": "cell motility", "d": ["Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071163", "l": "DNA replication preinitiation complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the DNA replication preinitiation complex, a protein-DNA complex that is assembled at DNA replication origins as part of initiation of DNA replication. The complex consists of proteins that initiate the DNA binding, melt the helix and enable helicase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905797", "l": "negative regulation of intraciliary anterograde transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary anterograde transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0071966", "l": "fungal-type cell wall polysaccharide metabolic process", "d": ["The chemical reactions and pathways involving the polysaccharides which make up the fungal-type cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046177", "l": "D-gluconate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904800", "l": "negative regulation of neuron remodeling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neuron remodeling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:1900542", "l": "regulation of purine nucleotide metabolic process", "d": ["Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902757", "l": "bis(molybdopterin guanine dinucleotide)molybdenum metabolic process", "d": ["The chemical reactions and pathways involving bis(molybdopterin guanine dinucleotide)molybdenum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071699", "l": "olfactory placode morphogenesis", "d": ["The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.470950656012619", "identifiers": [{"i": "GO:0007444", "l": "imaginal disc development", "d": ["The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905147", "l": "regulation of smooth muscle hypertrophy", "d": ["Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0007134", "l": "meiotic telophase I", "d": ["The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003029", "l": "detection of hypoxic conditions in blood by carotid body chemoreceptor signaling", "d": ["The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.036345600355318", "identifiers": [{"i": "GO:0072698", "l": "protein localization to microtubule cytoskeleton", "d": ["A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0014729", "l": "regulation of the velocity of shortening of skeletal muscle modulating contraction", "d": ["Any process that modulates velocity of shortening of a skeletal muscle contraction. The shortening leads to reduction of the length of muscle fibers and sarcomeres."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.011351901223186", "identifiers": [{"i": "GO:0002694", "l": "regulation of leukocyte activation", "d": ["Any process that modulates the frequency, rate, or extent of leukocyte activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:2000736", "l": "regulation of stem cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of stem cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0055022", "l": "negative regulation of cardiac muscle tissue growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000719", "l": "photoreactive repair", "d": ["The repair of UV-induced T-T, C-T and C-C dimers by directly reversing the damage to restore the original pyrimidines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904797", "l": "negative regulation of core promoter binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of core promoter binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021613", "l": "facial nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046450", "l": "dethiobiotin metabolic process", "d": ["The chemical reactions and pathways involving dethiobiotin, a derivative of biotin formed by replacing the sulfur atom by two hydrogen atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000836", "l": "positive regulation of androgen secretion", "d": ["Any process that activates or increases the frequency, rate or extent of androgen secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0061387", "l": "regulation of extent of cell growth", "d": ["Any process that modulates the extent of cell growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060320", "l": "rejection of self pollen", "d": ["The recognition and rejection of self pollen by cells in the stigma, mediated by the sharing and interaction of the single locus incompatibility haplotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006708", "l": "ecdysone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061238", "l": "establishment of planar polarity involved in mesonephric nephron morphogenesis", "d": ["Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015917", "l": "aminophospholipid transport", "d": ["The directed movement of aminophospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032349", "l": "positive regulation of aldosterone biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071912", "l": "asynchronous neurotransmitter secretion", "d": ["Release of neurotransmitter at the synapse that persists for tens to hundreds of milliseconds after action potential invasion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905455", "l": "positive regulation of myeloid progenitor cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0045876", "l": "positive regulation of sister chromatid cohesion", "d": ["Any process that activates or increases the frequency, rate or extent of sister chromatid cohesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.261443428098588", "identifiers": [{"i": "GO:0035738", "l": "envenomation resulting in modulation of process in another organism", "d": ["The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the manifestation of some change or damage to the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0019057", "l": "modulation by virus of host translation", "d": ["Any process in which a virus modulates the frequency, rate or extent of translation of host mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000860", "l": "positive regulation of aldosterone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of aldosterone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075272", "l": "regulation of zygosporangium development", "d": ["Any process that modulates the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015738", "l": "glucuronate transmembrane transport", "d": ["The process in which glucuronate is transported across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042531", "l": "positive regulation of tyrosine phosphorylation of STAT protein", "d": ["Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.523519163150823", "identifiers": [{"i": "GO:0001656", "l": "metanephros development", "d": ["The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0052372", "l": "modulation by symbiont of entry into host", "d": ["Any process in which an organism modulates the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0110029", "l": "negative regulation of meiosis I", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0046951", "l": "ketone body biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0016332", "l": "establishment or maintenance of polarity of embryonic epithelium", "d": ["Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization of epithelial cells in an embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099088", "l": "axonal transport of messenger ribonucleoprotein complex", "d": ["The directed movement of a messenger ribonucleoprotein complex along microtubules in axons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000854", "l": "positive regulation of corticosterone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of corticosterone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030381", "l": "chorion-containing eggshell pattern formation", "d": ["The regionalization process that gives rise to the structural pattern of a chorion-containing eggshell such as those found in insects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000562", "l": "negative regulation of CD4-positive, alpha-beta T cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904425", "l": "negative regulation of GTP binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of GTP binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901231", "l": "positive regulation of non-canonical Wnt signaling pathway via JNK cascade", "d": ["Any process that activates or increases the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0070339", "l": "response to bacterial lipopeptide", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009667", "l": "plastid inner membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the inner membrane of a plastid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903896", "l": "positive regulation of IRE1-mediated unfolded protein response", "d": ["Any process that activates or increases the frequency, rate or extent of the IRE1-mediated unfolded protein response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015901", "l": "cycloheximide transport", "d": ["The directed movement of cycloheximide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044652", "l": "adhesion of symbiont to host endothelial cell", "d": ["The attachment of a symbiont to a host endothelial cell via adhesion molecules, general stickiness etc., either directly or indirectly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903557", "l": "positive regulation of tumor necrosis factor superfamily cytokine production", "d": ["Any process that activates or increases the frequency, rate or extent of tumor necrosis factor superfamily cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044857", "l": "plasma membrane raft organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of plasma membrane rafts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0051495", "l": "positive regulation of cytoskeleton organization", "d": ["Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075529", "l": "establishment of latency as a circular episome", "d": ["A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a circular structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904202", "l": "negative regulation of iodide transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of iodide transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019358", "l": "nicotinate nucleotide salvage", "d": ["The generation of nicotinate nucleotide without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009242", "l": "colanic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of colanic acid, a capsular bacterial polysaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009087", "l": "methionine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042264", "l": "peptidyl-aspartic acid hydroxylation", "d": ["The hydroxylation of peptidyl-aspartic acid to form peptidyl-hydroxyaspartic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010499", "l": "proteasomal ubiquitin-independent protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome but do not involve ubiquitin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003005", "l": "follicular fluid formation in ovarian follicle antrum involved in scattered antral spaces stage", "d": ["The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the scattered antral spaces stage of oogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0075111", "l": "disruption of host receptor-mediated signal transduction", "d": ["Any process in which a symbiont interferes with receptor-mediated signal transduction in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903594", "l": "negative regulation of histamine secretion by mast cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of histamine secretion by mast cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003354", "l": "negative regulation of cilium movement", "d": ["Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0019474", "l": "L-lysine catabolic process to acetyl-CoA", "d": ["The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0002461", "l": "tolerance induction dependent upon immune response", "d": ["Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0120126", "l": "response to copper ion starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of copper ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903064", "l": "positive regulation of reverse cholesterol transport", "d": ["Any process that activates or increases the frequency, rate or extent of reverse cholesterol transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006228", "l": "UTP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UTP, uridine (5'-)triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0071103", "l": "DNA conformation change", "d": ["A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048724", "l": "epistomal sclerite development", "d": ["The process whose specific outcome is the progression of the epistomal sclerite over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902455", "l": "negative regulation of stem cell population maintenance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010480", "l": "microsporocyte differentiation", "d": ["The process aimed at the progression of a microsporocyte cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A microsporocyte is a diploid (2n) cell that undergoes meiosis and forms four haploid (1n) microspores; also called microspore mother cell and, in seed plants, pollen mother cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002470", "l": "plasmacytoid dendritic cell antigen processing and presentation", "d": ["The process in which a plasmacytoid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003139", "l": "secondary heart field specification", "d": ["The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090442", "l": "trehalose catabolism in response to heat stress", "d": ["The chemical reactions and pathways resulting in the degradation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001045", "l": "negative regulation of integrin-mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of integrin-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110155", "l": "NAD-cap decapping", "d": ["Cleavage of the 5'-NAD-cap of an RNA. The NAD-cap is present at the 5'-end of some RNAs in both bacetria and eukaryotes. While it promotes RNA stability in bacteria, it promotes RNA decay in eukaryotes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902940", "l": "positive regulation of intracellular calcium activated chloride channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of intracellular calcium activated chloride channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900962", "l": "regulation of methanophenazine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of methanophenazine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060482", "l": "lobar bronchus development", "d": ["The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903585", "l": "negative regulation of histone deubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of histone deubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070833", "l": "phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine", "d": ["The phosphatidylcholine biosynthetic process that begins with an initial N-methylation with phospho-base phosphoethanolamine, followed by two downstream N-methylations on phosphatidyl-bases, phosphatidyl-N-methylethanolamine and phosphatidyl-N-dimethylethanolamine. The process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002356", "l": "peripheral B cell negative selection", "d": ["Any process leading to negative selection of B cells in the periphery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0045987", "l": "positive regulation of smooth muscle contraction", "d": ["Any process that activates or increases the frequency, rate or extent of smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039724", "l": "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity", "d": ["Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of host I-kappa-B kinase epsilon (IKBKE/IKK-epsilon/IKK-E)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009152", "l": "purine ribonucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904662", "l": "positive regulation of sensory perception of bitter taste", "d": ["Any process that activates or increases the frequency, rate or extent of sensory perception of bitter taste."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.694848273704821", "identifiers": [{"i": "GO:0043648", "l": "dicarboxylic acid metabolic process", "d": ["The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0060041", "l": "retina development in camera-type eye", "d": ["The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0018194", "l": "peptidyl-alanine modification", "d": ["The modification of peptidyl-alanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051758", "l": "homologous chromosome movement towards spindle pole in meiosis I anaphase", "d": ["The directed movement of homologous chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis I anaphase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072573", "l": "tolerance induction to lipopolysaccharide", "d": ["Tolerance induction directed at lipopolysaccharide antigens."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061076", "l": "negative regulation of neural retina development", "d": ["Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015968", "l": "stringent response", "d": ["A specific global change in the metabolism of a bacterial cell (the downregulation of nucleic acid and protein synthesis, and the simultaneous upregulation of protein degradation and amino acid synthesis) as a result of starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901278", "l": "D-ribose 5-phosphate metabolic process", "d": ["The chemical reactions and pathways involving D-ribose 5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045627", "l": "positive regulation of T-helper 1 cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072000", "l": "extracellular polysaccharide catabolic process involved in ascospore release from ascus", "d": ["The chemical reactions and pathways resulting in the breakdown of polysaccharides in the ascus wall that contributes to the release of ascospores from the ascus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006216", "l": "cytidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cytidine, cytosine riboside, a widely distributed nucleoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:2001257", "l": "regulation of cation channel activity", "d": ["Any process that modulates the frequency, rate or extent of cation channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905756", "l": "regulation of primary cell septum biogenesis", "d": ["Any process that modulates the frequency, rate or extent of primary cell septum biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901860", "l": "positive regulation of mitochondrial DNA metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072488", "l": "ammonium transmembrane transport", "d": ["The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010738", "l": "regulation of protein kinase A signaling", "d": ["Any process that modulates the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002130", "l": "wobble position ribose methylation", "d": ["The process in which the ribose base of the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'O position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0050820", "l": "positive regulation of coagulation", "d": ["Any process that activates or increases the frequency, rate or extent of coagulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001765", "l": "membrane raft assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a membrane raft, a small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalizes cellular processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "48.212388946394306", "identifiers": [{"i": "GO:0051239", "l": "regulation of multicellular organismal process", "d": ["Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120112", "l": "UDP-glucose transmembrane transport into endoplasmic reticulum", "d": ["The directed movement of UDP-glucose from cytosol to endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006593", "l": "ornithine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0019405", "l": "alditol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0030970", "l": "retrograde protein transport, ER to cytosol", "d": ["The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytosol through the translocon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001193", "l": "positive regulation of gamma-delta T cell activation involved in immune response", "d": ["Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation involved in immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1905651", "l": "regulation of artery morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of artery morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902647", "l": "negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:1902983", "l": "DNA strand elongation involved in mitotic DNA replication", "d": ["Any DNA strand elongation involved in mitotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905363", "l": "positive regulation of endosomal vesicle fusion", "d": ["Any process that activates or increases the frequency, rate or extent of endosomal vesicle fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900972", "l": "negative regulation of sarcinapterin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901180", "l": "spheroidene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of spheroidene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002849", "l": "regulation of peripheral T cell tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of peripheral T cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900216", "l": "positive regulation of apoptotic process involved in metanephric collecting duct development", "d": ["Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.622337805354121", "identifiers": [{"i": "GO:0050777", "l": "negative regulation of immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009778", "l": "cyclic photosynthetic phosphorylation", "d": ["A photosynthetic phosphorylation process in which ATP synthesis is driven by a proton gradient generated across the thylakoid membrane. Involves only photosystem I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014885", "l": "detection of injury involved in regulation of muscle adaptation", "d": ["The series of events by which an injury stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903642", "l": "regulation of recombination hotspot binding", "d": ["Any process that modulates the frequency, rate or extent of recombination hotspot binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1901018", "l": "positive regulation of potassium ion transmembrane transporter activity", "d": ["Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "47.250820037527795", "identifiers": [{"i": "GO:0090304", "l": "nucleic acid metabolic process", "d": ["Any cellular metabolic process involving nucleic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900336", "l": "regulation of methane biosynthetic process from carbon monoxide", "d": ["Any process that modulates the frequency, rate or extent of methane biosynthetic process from carbon monoxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.161881760686384", "identifiers": [{"i": "GO:0051303", "l": "establishment of chromosome localization", "d": ["The directed movement of a chromosome to a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019091", "l": "mitochondrial lrRNA export from mitochondrion", "d": ["The process in which a lrRNA, large subunit ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.214786017368347", "identifiers": [{"i": "GO:0006643", "l": "membrane lipid metabolic process", "d": ["The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070959", "l": "negative regulation of neutrophil mediated killing of fungus", "d": ["Any process that decreases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035043", "l": "male pronuclear envelope synthesis", "d": ["Assembly of a nuclear envelope containing nuclear pores and a lamina around the male pronucleus, the final step in sperm pronuclear formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0097428", "l": "protein maturation by iron-sulfur cluster transfer", "d": ["The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0034093", "l": "positive regulation of maintenance of sister chromatid cohesion", "d": ["Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.141482614631713", "identifiers": [{"i": "GO:0098656", "l": "monoatomic anion transmembrane transport", "d": ["The process in which a monoatomic anion is transported across a membrane. Monatomic anions (also called simple anions) are negatively charged ions consisting of exactly one atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0090158", "l": "endoplasmic reticulum membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an endoplasmic reticulum membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046313", "l": "phosphoarginine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphoarginine, a phosphorylated derivative of the amino acid arginine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902527", "l": "positive regulation of protein monoubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein monoubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902372", "l": "positive regulation of tRNA catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of tRNA catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044790", "l": "suppression of viral release by host", "d": ["A process in which a host organism stops, prevents or reduces the frequency, rate or extent of the release of a virus with which it is infected, from its cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048766", "l": "root hair initiation", "d": ["The process in which a protrusion or bulge is formed at the site of plant root hair outgrowth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900184", "l": "negative regulation of xanthone-containing compound biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of xanthone-containing compound biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903626", "l": "positive regulation of DNA catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of DNA catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902519", "l": "response to docetaxel trihydrate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a docetaxel trihydrate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:1902624", "l": "positive regulation of neutrophil migration", "d": ["Any process that activates or increases the frequency, rate or extent of neutrophil migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0090716", "l": "adaptive immune memory response", "d": ["An immune response directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0008608", "l": "attachment of spindle microtubules to kinetochore", "d": ["The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010716", "l": "negative regulation of extracellular matrix disassembly", "d": ["Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.207992593949683", "identifiers": [{"i": "GO:0007411", "l": "axon guidance", "d": ["The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044762", "l": "negative regulation by symbiont of host neurotransmitter secretion", "d": ["Any process in which a symbiont organism negatively regulates the regulated release of a neurotransmitter from a cell in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032979", "l": "protein insertion into mitochondrial inner membrane from matrix", "d": ["The process in which a protein is incorporated into the mitochondrial inner membrane from the matrix side. This includes membrane insertion of newly synthesized mitochondrially-encoded proteins, and insertion of nuclear-encoded proteins after their import into the mitochondrial matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019264", "l": "glycine biosynthetic process from serine", "d": ["The chemical reactions and pathways resulting in the formation of glycine from other compounds, including serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900431", "l": "regulation of filamentous growth of a population of unicellular organisms in response to heat", "d": ["Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.357413409522593", "identifiers": [{"i": "GO:0010639", "l": "negative regulation of organelle organization", "d": ["Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000170", "l": "positive regulation of peptidyl-cysteine S-nitrosylation", "d": ["Any process that activates or increases the frequency, rate or extent of peptidyl-cysteine S-nitrosylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051409", "l": "response to nitrosative stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0010466", "l": "negative regulation of peptidase activity", "d": ["Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902218", "l": "regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "d": ["Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120265", "l": "negative regulation of chromosome attachment to the nuclear envelope", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chromosome attachment to the nuclear envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0052128", "l": "positive energy taxis", "d": ["The directed movement of a motile cell or organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042006", "l": "masculinization of hermaphroditic germ-line", "d": ["The determination of male sex and sexual phenotype in the germ-line of the hermaphrodite. An example of this is found in Caenorhabditis elegans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:0031333", "l": "negative regulation of protein-containing complex assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0032352", "l": "positive regulation of hormone metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018979", "l": "trichloroethylene metabolic process", "d": ["The chemical reactions and pathways involving trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009727", "l": "detection of ethylene stimulus", "d": ["The series of events in which an ethylene (ethene) stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0014050", "l": "negative regulation of glutamate secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060878", "l": "pouch outgrowth involved in semicircular canal formation", "d": ["The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002650", "l": "negative regulation of tolerance induction to self antigen", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to self antigen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140237", "l": "translation at presynapse, modulating chemical synaptic transmission", "d": ["Translation that occurs at the presynapse, and that modulates chemical synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010813", "l": "neuropeptide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of neuropeptides. Neuropeptides are signaling peptides that travel across a synaptic junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904159", "l": "megasporocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a megasporocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.116918913335823", "identifiers": [{"i": "GO:0002673", "l": "regulation of acute inflammatory response", "d": ["Any process that modulates the frequency, rate, or extent of an acute inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043463", "l": "regulation of rhamnose catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0006863", "l": "purine nucleobase transport", "d": ["The directed movement of purine bases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033340", "l": "pelvic fin development", "d": ["The process whose specific outcome is the progression of the pelvic fin over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0086073", "l": "bundle of His cell-Purkinje myocyte adhesion involved in cell communication", "d": ["The attachment of a bundle of His cell to a Purkinje myocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0000303", "l": "response to superoxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0006301", "l": "postreplication repair", "d": ["The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. Includes pathways that remove replication-blocking lesions in conjunction with DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0021988", "l": "olfactory lobe development", "d": ["The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009104", "l": "lipopolysaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000554", "l": "regulation of T-helper 1 cell cytokine production", "d": ["Any process that modulates the frequency, rate or extent of T-helper 1 cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090706", "l": "specification of plant organ position", "d": ["The regionalization process in which information that determines the correct position at which plant organ primordia are formed is generated and perceived resulting in correct positioning of the new plant organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090611", "l": "ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905650", "l": "positive regulation of shell calcification", "d": ["Any process that activates or increases the frequency, rate or extent of shell calcification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160061", "l": "respiratory chemosensitivity", "d": ["A homeostatic process by which the sensing of CO2 and/or H+ by the brain leads to appropriate altering in breathing to regulate blood gas and tissue pH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0045986", "l": "negative regulation of smooth muscle contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0003099", "l": "positive regulation of the force of heart contraction by chemical signal", "d": ["Any process which increases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035756", "l": "transepithelial migration of symbiont in host", "d": ["The directional movement of an organism from one side of an epithelium to the other within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061287", "l": "mesonephric capsule formation", "d": ["The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035075", "l": "response to ecdysone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.510429476229447", "identifiers": [{"i": "GO:0071674", "l": "mononuclear cell migration", "d": ["The movement of a mononuclear cell within or between different tissues and organs of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072046", "l": "establishment of planar polarity involved in nephron morphogenesis", "d": ["Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002875", "l": "negative regulation of chronic inflammatory response to antigenic stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0001705", "l": "ectoderm formation", "d": ["The formation of ectoderm during gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019506", "l": "phenylmercury acetate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0043331", "l": "response to dsRNA", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905013", "l": "negative regulation of 'de novo' NAD biosynthetic process from tryptophan", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "36.754032874780556", "identifiers": [{"i": "GO:0048646", "l": "anatomical structure formation involved in morphogenesis", "d": ["The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070964", "l": "positive regulation of neutrophil mediated killing of gram-positive bacterium", "d": ["Any process that increases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060127", "l": "prolactin secreting cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032661", "l": "regulation of interleukin-18 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-18 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000310", "l": "regulation of NMDA receptor activity", "d": ["Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905235", "l": "response to quercetin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019618", "l": "protocatechuate catabolic process, ortho-cleavage", "d": ["The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield beta-ketoadipate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.523519163150823", "identifiers": [{"i": "GO:0010970", "l": "transport along microtubule", "d": ["The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030836", "l": "positive regulation of actin filament depolymerization", "d": ["Any process that activates or increases the frequency, rate or extent of actin depolymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075018", "l": "positive regulation of appressorium formation", "d": ["Any process that activates or increases the frequency, rate or extent of symbiont appressorium formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060440", "l": "trachea formation", "d": ["The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0043279", "l": "response to alkaloid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902619", "l": "regulation of microtubule minus-end binding", "d": ["Any process that modulates the frequency, rate or extent of microtubule minus-end binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0051402", "l": "neuron apoptotic process", "d": ["Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.572744119402742", "identifiers": [{"i": "GO:0071417", "l": "cellular response to organonitrogen compound", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.527781272052167", "identifiers": [{"i": "GO:0044851", "l": "hair cycle phase", "d": ["The cyclical periods of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060528", "l": "secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development", "d": ["The process in which a relatively unspecialized epithelial cell acquires specialized features of a secretory columnal luminar epithelial cell of the prostate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0033233", "l": "regulation of protein sumoylation", "d": ["Any process that modulates the frequency, rate or extent of the addition of SUMO groups to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045797", "l": "positive regulation of intestinal cholesterol absorption", "d": ["Any process that activates or increases the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052403", "l": "negative regulation by host of symbiont catalytic activity", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont enzyme activity. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0060966", "l": "regulation of gene silencing by regulatory ncRNA", "d": ["Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046178", "l": "D-gluconate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903187", "l": "negative regulation of vitellogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vitellogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0031649", "l": "heat generation", "d": ["Any homeostatic process in which an organism produces heat, thereby raising its internal temperature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0009608", "l": "response to symbiont", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiont, an organism living with an organism of a different species in close physical association. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010772", "l": "meiotic DNA recombinase assembly involved in reciprocal meiotic recombination", "d": ["The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903277", "l": "negative regulation of sodium ion export across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion export across the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045054", "l": "constitutive secretory pathway", "d": ["A process of exocytosis found in all eukaryotic cells, in which transport vesicles destined for the plasma membrane leave the trans-Golgi network in a steady stream. Upon exocytosis, the membrane proteins and lipids in these vesicles provide new components for the plasma membrane, and the soluble proteins inside the vesicles are released into the extracellular space."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.009127879491089", "identifiers": [{"i": "GO:0010629", "l": "negative regulation of gene expression", "d": ["Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140742", "l": "lncRNA transcription", "d": ["The transcription of lncRNAs, non-coding RNAs over 200 nucleotides in length, from a DNA template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032325", "l": "molybdopterin cofactor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0061162", "l": "establishment of monopolar cell polarity", "d": ["The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031273", "l": "negative regulation of pseudopodium assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033529", "l": "raffinose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904161", "l": "DNA synthesis involved in UV-damage excision repair", "d": ["Any DNA synthesis that is involved in UV-damage excision repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035921", "l": "desmosome disassembly", "d": ["The controlled breakdown of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035915", "l": "pore formation in membrane of another organism", "d": ["The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0051446", "l": "positive regulation of meiotic cell cycle", "d": ["Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0006578", "l": "amino-acid betaine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any betaine, the N-trimethyl derivative of an amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061334", "l": "cell rearrangement involved in Malpighian tubule morphogenesis", "d": ["The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903586", "l": "positive regulation of histone deubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of histone deubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090273", "l": "regulation of somatostatin secretion", "d": ["Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905955", "l": "negative regulation of endothelial tube morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042789", "l": "mRNA transcription by RNA polymerase II", "d": ["The cellular synthesis of messenger RNA (mRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.692830315749546", "identifiers": [{"i": "GO:0030163", "l": "protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.825956045430587", "identifiers": [{"i": "GO:0071478", "l": "cellular response to radiation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1903747", "l": "regulation of establishment of protein localization to mitochondrion", "d": ["Any process that modulates the frequency, rate or extent of establishment of protein localization to mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060421", "l": "positive regulation of heart growth", "d": ["Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010312", "l": "detoxification of zinc ion", "d": ["Any process that reduces or removes the toxicity of zinc ion. These include transport of zinc away from sensitive areas and to compartments or complexes whose purpose is sequestration of zinc ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0033364", "l": "mast cell secretory granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a mast cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905355", "l": "spine apparatus assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a spine apparatus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000568", "l": "positive regulation of memory T cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of memory T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904431", "l": "positive regulation of t-circle formation", "d": ["Any process that activates or increases the frequency, rate or extent of t-circle formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050762", "l": "depsipeptide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:2000725", "l": "regulation of cardiac muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042885", "l": "microcin B17 transport", "d": ["The directed movement of microcin B17, a bactericidal peptide (antibiotic) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904133", "l": "regulation of convergent extension involved in rhombomere morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002845", "l": "positive regulation of tolerance induction to tumor cell", "d": ["Any process that activates or increases the frequency, rate, or extent of tolerance induction to tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060331", "l": "negative regulation of response to type II interferon", "d": ["Any process that decreases the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042344", "l": "indole glucosinolate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904445", "l": "negative regulation of establishment of Sertoli cell barrier", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of Sertoli cell barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0016180", "l": "snRNA processing", "d": ["Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule. The primary function of snRNAs is processing pre-messenger RNA in the nucleus. They have also been shown to aid in the regulation of transcription factors (7SK RNA) or RNA polymerase II (B2 RNA), and maintaining the telomeres."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0072598", "l": "protein localization to chloroplast", "d": ["A process in which a protein is transported to, or maintained at, a location in a chloroplast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000866", "l": "positive regulation of estradiol secretion", "d": ["Any process that activates or increases the frequency, rate or extent of estradiol secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045614", "l": "negative regulation of plasmatocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of plasmatocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.693904365167544", "identifiers": [{"i": "GO:1901566", "l": "organonitrogen compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of organonitrogen compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900935", "l": "regulation of nonadec-1-ene biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of nonadec-1-ene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:0035930", "l": "corticosteroid hormone secretion", "d": ["The regulated release of any corticosteroid hormone into the circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900110", "l": "negative regulation of histone H3-K9 dimethylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 dimethylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070256", "l": "negative regulation of mucus secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2000793", "l": "cell proliferation involved in heart valve development", "d": ["Any cell proliferation that is involved in heart valve development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033305", "l": "chlorophyll a biosynthetic process", "d": ["The chemical reactions and pathways leading to the formation of chlorophyll a."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000740", "l": "negative regulation of mesenchymal stem cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032338", "l": "regulation of inhibin secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of inhibin from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905578", "l": "regulation of ERBB3 signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of ERBB3 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046579", "l": "positive regulation of Ras protein signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of Ras protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010430", "l": "fatty acid omega-oxidation", "d": ["A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048168", "l": "regulation of neuronal synaptic plasticity", "d": ["A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0140886", "l": "suppression by virus of host interferon-mediated signaling pathway", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of interferon-mediated signaling in the host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "37.126796387341173", "identifiers": [{"i": "GO:0060562", "l": "epithelial tube morphogenesis", "d": ["The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002873", "l": "positive regulation of natural killer cell tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904325", "l": "positive regulation of inhibitory G protein-coupled receptor phosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032920", "l": "putrescine acetylation", "d": ["The modification of putrescine by addition of acetyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000330", "l": "positive regulation of T-helper 17 cell lineage commitment", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 17 cell lineage commitment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072072", "l": "kidney stroma development", "d": ["The process whose specific outcome is the progression of the kidney stroma over time, from its formation to the mature structure. The kidney stroma is the mesenchyme of the mature kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0090033", "l": "positive regulation of filamentous growth", "d": ["Any process that increases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048803", "l": "imaginal disc-derived male genitalia morphogenesis", "d": ["The process in which the anatomical structures of male genitalia are generated and organized from the genital imaginal disc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.100061334875598", "identifiers": [{"i": "GO:0006865", "l": "amino acid transport", "d": ["The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060148", "l": "positive regulation of post-transcriptional gene silencing", "d": ["Any process that increases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035336", "l": "long-chain fatty-acyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0033375", "l": "protease localization to T cell secretory granule", "d": ["Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "48.497049470841688", "identifiers": [{"i": "GO:0006836", "l": "neurotransmitter transport", "d": ["The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042902", "l": "peptidoglycan-protein cross-linking via L-threonyl-pentaglycyl-murein", "d": ["The process of linking a protein to peptidoglycan via a carboxy terminal threonine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0060912", "l": "cardiac cell fate specification", "d": ["The process involved in the specification of cardiac cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060376", "l": "positive regulation of mast cell differentiation", "d": ["Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900081", "l": "regulation of arginine catabolic process", "d": ["Any process that modulates the frequency, rate or extent of arginine catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904405", "l": "cellular response to formaldehyde", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010723", "l": "positive regulation of transcription from RNA polymerase II promoter in response to iron", "d": ["Any process that increases the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019296", "l": "coenzyme M metabolic process", "d": ["The chemical reactions and pathways involving coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "35.536597171249042", "identifiers": [{"i": "GO:0002164", "l": "larval development", "d": ["The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.531755541456754", "identifiers": [{"i": "GO:0019748", "l": "secondary metabolic process", "d": ["The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:1903050", "l": "regulation of proteolysis involved in protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of proteolysis involved in cellular catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051342", "l": "regulation of cyclic-nucleotide phosphodiesterase activity", "d": ["Any process that modulates the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0061687", "l": "detoxification of inorganic compound", "d": ["Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006217", "l": "deoxycytidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033528", "l": "S-methylmethionine cycle", "d": ["A cyclic series of interconversions involving S-methyl-L-methionine, S-adenosyl-L-homocysteine, S-adenosyl-L-methionine, L-homocysteine, and L-methionine. Converts the methionine group of adenosylmethionine back to free methionine, and may serve regulate the cellular adenosylmethionine level."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001284", "l": "regulation of BMP secretion", "d": ["Any process that modulates the frequency, rate or extent of BMP secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000029", "l": "regulation of proanthocyanidin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of proanthocyanidin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070384", "l": "Harderian gland development", "d": ["The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0110105", "l": "mRNA cleavage and polyadenylation specificity factor complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the mRNA cleavage and polyadenylation specificity factor complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0015798", "l": "myo-inositol transport", "d": ["The directed movement of myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900664", "l": "regulation of emodin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of emodin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035573", "l": "N-terminal peptidyl-serine trimethylation", "d": ["The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905491", "l": "positive regulation of sensory neuron axon guidance", "d": ["Any process that activates or increases the frequency, rate or extent of sensory neuron axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097716", "l": "copper ion transport across blood-brain barrier", "d": ["The directed movement of copper (Cu) ions passing through the blood-brain barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904618", "l": "positive regulation of actin binding", "d": ["Any process that activates or increases the frequency, rate or extent of actin binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071932", "l": "replication fork reversal", "d": ["Replication fork processing that involves the unwinding of blocked forks to form four-stranded structures resembling Holliday junctions, which are subsequently resolved."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0090207", "l": "regulation of triglyceride metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905922", "l": "negative regulation of acetylcholine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900509", "l": "regulation of pentose catabolic process to ethanol", "d": ["Any process that modulates the frequency, rate or extent of pentose catabolic process to ethanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032053", "l": "ciliary basal body organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018220", "l": "peptidyl-threonine palmitoylation", "d": ["The covalent attachment of a palmitoyl group to an oxygen (O) atom in a threonine residue to form peptidyl-O-palmitoyl-L-threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034959", "l": "endothelin maturation", "d": ["The process leading to the attainment of the full functional capacity of endothelin by conversion of Big-endothelin substrate into mature endothelin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900883", "l": "17-methylnonadec-1-ene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 17-methylnonadec-1-ene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048261", "l": "negative regulation of receptor-mediated endocytosis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0003308", "l": "negative regulation of Wnt signaling pathway involved in heart development", "d": ["Any process that decreases the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904257", "l": "zinc ion import into Golgi lumen", "d": ["The directed import of zinc(2+) from the cytosol across the Golgi membrane into the Golgi lumen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0060977", "l": "coronary vasculature morphogenesis", "d": ["The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060715", "l": "syncytiotrophoblast cell differentiation involved in labyrinthine layer development", "d": ["The process in which a chorionic trophoblast cell acquires specialized features of a syncytiotrophoblast of the labyrinthine layer of the placenta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901357", "l": "beta-D-galactofuranose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of beta-D-galactofuranose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140450", "l": "protein targeting to Golgi apparatus", "d": ["The process of targeting specific proteins to the Golgi apparatus. Usually requires an organelle-specific protein sequence motif or a protein modification (for example a palmitoylation)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048335", "l": "negative regulation of mesodermal cell fate determination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0007483", "l": "genital disc morphogenesis", "d": ["The process in which the anatomical structures derived from the genital disc are generated and organized. This includes the transformation of a genital imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult genital structures, the anal plates and the hind gut."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010044", "l": "response to aluminum ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0000073", "l": "initial mitotic spindle pole body separation", "d": ["The release of duplicated mitotic spindle pole bodies (SPBs) that begins with the nucleation of microtubules from each SPB within the nucleus, leading to V-shaped spindle microtubules. Interpolar microtubules that elongate from each pole are interconnected, forming overlapping microtubules. Capturing and antiparallel sliding apart of microtubules promotes the initial separation of the SPB."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.866234286307446", "identifiers": [{"i": "GO:0050817", "l": "coagulation", "d": ["The process in which a fluid solution, or part of it, changes into a solid or semisolid mass."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046603", "l": "negative regulation of mitotic centrosome separation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of centrosome separation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032238", "l": "adenosine transport", "d": ["The directed movement of adenosine, adenine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0001737", "l": "establishment of imaginal disc-derived wing hair orientation", "d": ["Orientation of hairs in the imaginal disc-derived wing along a proximal-distal axis, such that each cell of the wing produces one wing hair which points in a distal direction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.193892402340154", "identifiers": [{"i": "GO:0071396", "l": "cellular response to lipid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1904104", "l": "negative regulation of convergent extension involved in gastrulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003276", "l": "apoptotic process involved in heart valve morphogenesis", "d": ["Any apoptotic process that contributes to the shaping of a heart valve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001987", "l": "vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure", "d": ["A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the baroreceptor response to decreased blood pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034487", "l": "vacuolar amino acid transmembrane transport", "d": ["The process in which an amino acid is transported from one side of the vacuolar membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070973", "l": "protein localization to endoplasmic reticulum exit site", "d": ["A process in which a protein is transported to, or maintained in, a location at an endoplasmic reticulum exit site."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042942", "l": "D-serine transport", "d": ["The directed movement of D-serine, the D-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036102", "l": "leukotriene B4 metabolic process", "d": ["The chemical reactions and pathways involving leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032714", "l": "negative regulation of interleukin-5 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042069", "l": "regulation of catecholamine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.783030043623796", "identifiers": [{"i": "GO:0002292", "l": "T cell differentiation involved in immune response", "d": ["The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043318", "l": "negative regulation of cytotoxic T cell degranulation", "d": ["Any process that stops, prevents, or reduces the rate of cytotoxic T cell degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061760", "l": "antifungal innate immune response", "d": ["An defense response against a fungus mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0007063", "l": "regulation of sister chromatid cohesion", "d": ["Any process that modulates the frequency, rate or extent of sister chromatid cohesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901941", "l": "(+)-epi-alpha-bisabolol metabolic process", "d": ["The chemical reactions and pathways involving (+)-epi-alpha-bisabolol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0007422", "l": "peripheral nervous system development", "d": ["The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045629", "l": "negative regulation of T-helper 2 cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009825", "l": "multidimensional cell growth", "d": ["The process in which a cell irreversibly increases in size in two or three [spatial] dimensions or along two or three axes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060820", "l": "inactivation of X chromosome by heterochromatin formation", "d": ["Compensating for the two-fold variation in X-chromosome: autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by the mechanism of heterochromatin formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.757808809870852", "identifiers": [{"i": "GO:0033993", "l": "response to lipid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0062121", "l": "linear element maturation", "d": ["The meiotic cell cycle chromosome organization process in which LinE complexes closely associate with chromatin during meiotic prophase to form mature linear elements."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080038", "l": "positive regulation of cytokinin-activated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of cytokinin signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061583", "l": "colon epithelial cell chemotaxis", "d": ["The directed movement of a colon epithelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036377", "l": "arbuscular mycorrhizal association", "d": ["A form of mutualism between a fungus and the roots of a vascular plant, where hyphae of the fungus penetrate the plant cell wall and invaginate its cell membrane. Once inside, the fungus forms highly branched structures for nutrient exchange with the plant called arbuscules. Aids in the acquisition by the plant of nutrients such as phosphorus from the soil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072749", "l": "cellular response to cytochalasin B", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901926", "l": "cadinene metabolic process", "d": ["The chemical reactions and pathways involving cadinene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019667", "l": "anaerobic L-alanine catabolic process", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of L-alanine, yielding energy in the form of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019921", "l": "peptidyl-1-thioglycine biosynthetic process, carboxy-terminal", "d": ["The chemical reactions and pathways resulting in the formation of carboxy-terminal peptidyl-1-thioglycine, which has a carboxy-terminal thiocarboxy-C(=O)-SH bond."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0001523", "l": "retinoid metabolic process", "d": ["The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904816", "l": "positive regulation of protein localization to chromosome, telomeric region", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to chromosome, telomeric region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905312", "l": "positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904535", "l": "positive regulation of telomeric loop disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of telomeric loop disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901353", "l": "positive regulation of phosphatidylglycerol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylglycerol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017190", "l": "N-terminal peptidyl-aspartic acid acetylation", "d": ["The acetylation of the N-terminal aspartic acid of proteins; catalyzed by aspartate N-acetyltransferase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903814", "l": "regulation of collecting lymphatic vessel constriction", "d": ["Any process that modulates the frequency, rate or extent of collecting lymphatic vessel constriction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046399", "l": "glucuronate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucuronate, the anion of glucuronic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000007", "l": "negative regulation of metanephric comma-shaped body morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric comma-shaped body morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051289", "l": "protein homotetramerization", "d": ["The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032669", "l": "regulation of interleukin-25 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-25 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0003151", "l": "outflow tract morphogenesis", "d": ["The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010451", "l": "floral meristem growth", "d": ["The increase in size or mass of a floral meristem, a population of undifferentiated cells in a plant that gives rise to a flower."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032015", "l": "regulation of Ran protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of Ran protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905357", "l": "negative regulation of snRNA pseudouridine synthesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of snRNA pseudouridine synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046169", "l": "methanol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903181", "l": "positive regulation of dopamine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110161", "l": "positive regulation of mitotic spindle formation (spindle phase one)", "d": ["Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070269", "l": "pyroptosis", "d": ["A caspase-1-dependent cell death subroutine that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048304", "l": "positive regulation of isotype switching to IgG isotypes", "d": ["Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.905834266688807", "identifiers": [{"i": "GO:0098542", "l": "defense response to other organism", "d": ["Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990086", "l": "lens fiber cell apoptotic process", "d": ["Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0032543", "l": "mitochondrial translation", "d": ["The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090125", "l": "cell-cell adhesion involved in synapse maturation", "d": ["The attachment of the pre-synaptic cell to the post-synaptic cell via adhesion molecules that contributes to synapse maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098873", "l": "neuronal action potential back-propagation", "d": ["Propagation of an action potential in a neuron, from its site of initiation (typically the axon hillock) towards the soma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:1903533", "l": "regulation of protein targeting", "d": ["Any process that modulates the frequency, rate or extent of protein targeting."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140460", "l": "response to Gram-negative bacterium", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-negative bacterium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0010015", "l": "root morphogenesis", "d": ["The process in which the anatomical structures of roots are generated and organized. The root is the usually underground part of a seed plant body that originates from the hypocotyl, functions as an organ of absorption, aeration, and food storage or as a means of anchorage and support."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048263", "l": "determination of dorsal identity", "d": ["Determination of the identity of part of an organism or organ where those parts are of the type that occur in the dorsal region. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019125", "l": "peptidyl-phenylalanine racemization", "d": ["The racemization of peptidyl-phenylalanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051097", "l": "negative regulation of helicase activity", "d": ["Any process that stops or reduces the activity of a helicase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0042274", "l": "ribosomal small subunit biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034303", "l": "myxospore formation", "d": ["The process in which differentiated, resting cells are formed, usually within a fruiting body by Myxobacteria. The myxospore is more resistant to high temperature, dessication, and UV than vegetative myxobacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.281967957033203", "identifiers": [{"i": "GO:1903034", "l": "regulation of response to wounding", "d": ["Any process that modulates the frequency, rate or extent of response to wounding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075510", "l": "macropinocytosis involved in viral entry into host cell", "d": ["Any macropinocytosis that is involved in the uptake of a virus into a host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0019419", "l": "sulfate reduction", "d": ["The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900399", "l": "positive regulation of pyrimidine nucleotide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of pyrimidine nucleotide biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0099563", "l": "modification of synaptic structure", "d": ["Any process that modifies the structure/morphology of a synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042414", "l": "epinephrine metabolic process", "d": ["The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0048634", "l": "regulation of muscle organ development", "d": ["Any process that modulates the frequency, rate or extent of muscle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0046902", "l": "regulation of mitochondrial membrane permeability", "d": ["Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905873", "l": "positive regulation of protein localization to cell leading edge", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060702", "l": "negative regulation of endoribonuclease activity", "d": ["Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0031335", "l": "regulation of sulfur amino acid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021943", "l": "formation of radial glial scaffolds", "d": ["The formation of scaffolds from a radial glial cell. The scaffolds are used as a substrate for the radial migration of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010803", "l": "regulation of tumor necrosis factor-mediated signaling pathway", "d": ["Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048134", "l": "germ-line cyst formation", "d": ["Formation of a group of interconnected cells derived from a single gonial founder cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000455", "l": "enzyme-directed rRNA pseudouridine synthesis", "d": ["The intramolecular conversion of uridine to pseudouridine during ribosome biogenesis where the enzyme specifies the site that becomes pseudouridylated without using a guide RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035583", "l": "sequestering of TGFbeta in extracellular matrix", "d": ["Confining TGFbeta to the extracellular matrix (ECM) such that it is separated from other components of the signaling pathway, including its cell surface receptor. TGFbeta is secreted as part of a latent complex that is targeted to the extracellular matrix through latent-TGFbeta-binding protein (LTBP)-mediated association with matrix proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034181", "l": "positive regulation of toll-like receptor 13 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 13 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0097090", "l": "presynaptic membrane organization", "d": ["A process which results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0055018", "l": "regulation of cardiac muscle fiber development", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle fiber development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.783030043623796", "identifiers": [{"i": "GO:0045927", "l": "positive regulation of growth", "d": ["Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043929", "l": "primary ovarian follicle growth involved in double layer follicle stage", "d": ["Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle), as part of the double layer follicle stage of oogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0016926", "l": "protein desumoylation", "d": ["The process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007139", "l": "meiotic telophase II", "d": ["The cell cycle phase which follows anaphase II of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051135", "l": "positive regulation of NK T cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905311", "l": "negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.569439710577498", "identifiers": [{"i": "GO:0043434", "l": "response to peptide hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0090592", "l": "DNA synthesis involved in DNA replication", "d": ["Synthesis of DNA that is a part of the process of duplicating one or more molecules of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022032", "l": "telencephalon oligodendrocyte cell migration", "d": ["The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900925", "l": "positive regulation of glycine import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of glycine import."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0042946", "l": "glucoside transport", "d": ["The directed movement of glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucosides are glycosides in which the sugar group is a glucose residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0007443", "l": "Malpighian tubule morphogenesis", "d": ["The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042740", "l": "exogenous antibiotic catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated externally to the cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0006635", "l": "fatty acid beta-oxidation", "d": ["A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903370", "l": "positive regulation of foraging behavior", "d": ["Any process that activates or increases the frequency, rate or extent of foraging behavior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0062232", "l": "prostanoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of prostanoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902487", "l": "protein localization to non-growing cell tip", "d": ["A process in which a protein is transported to, or maintained in, a location within a non-growing cell tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044640", "l": "envenomation resulting in negative regulation of complement activation, lectin pathway in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the lectin pathway in the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0032987", "l": "protein-lipid complex disassembly", "d": ["The disaggregation of a protein-lipid complex into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120179", "l": "adherens junction disassembly", "d": ["The disaggregation of an adherens junction into its constituent components. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006490", "l": "oligosaccharide-lipid intermediate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an oligosaccharide-lipid intermediate, such as a molecule of dolichol-P-man or dolicol-P-Glc used in N-linked glycosylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0072312", "l": "metanephric glomerular epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033591", "l": "response to L-ascorbic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905859", "l": "negative regulation of heparan sulfate proteoglycan binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate proteoglycan binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.062480095235458", "identifiers": [{"i": "GO:0018198", "l": "peptidyl-cysteine modification", "d": ["The modification of peptidyl-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0050787", "l": "detoxification of mercury ion", "d": ["Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg[II]) to metallic mercury (Hg[0])."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0032353", "l": "negative regulation of hormone biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033358", "l": "UDP-L-arabinose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044541", "l": "zymogen activation in another organism", "d": ["The chemical reactions and pathways performed by an organism resulting in the proteolytic processing of an inactive enzyme to an active form in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061156", "l": "pulmonary artery morphogenesis", "d": ["The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0031087", "l": "deadenylation-independent decapping of nuclear-transcribed mRNA", "d": ["Cleavage of the 5'-cap of a nuclear-transcribed mRNA that is independent of poly(A) tail shortening."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0048791", "l": "calcium ion-regulated exocytosis of neurotransmitter", "d": ["The release of a neurotransmitter into the synaptic cleft by exocytosis of synaptic vesicles, where the release step is dependent on a rise in cytosolic calcium ion levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000512", "l": "negative regulation of granzyme A production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of granzyme A production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030720", "l": "oocyte localization involved in germarium-derived egg chamber formation", "d": ["Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903087", "l": "mitotic spindle pole body duplication", "d": ["Any spindle pole body duplication that is involved in the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900705", "l": "negative regulation of siderophore biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of siderophore biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0015706", "l": "nitrate transmembrane transport", "d": ["The directed movement of nitrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0150155", "l": "interleukin-34 production", "d": ["The appearance of interleukin-34 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033471", "l": "GDP-L-galactose metabolic process", "d": ["The chemical reactions and pathways involving GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035008", "l": "positive regulation of melanization defense response", "d": ["Any process that increases the rate or extent of the melanization defense response during injury or invasion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061169", "l": "positive regulation of hair placode formation", "d": ["Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019251", "l": "anaerobic cobalamin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090445", "l": "positive regulation of nematode larval development, heterochronic", "d": ["Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and increases the rate at which this time point is reached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106303", "l": "mannogen metabolic process", "d": ["The chemical reactions and pathways involving mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0007624", "l": "ultradian rhythm", "d": ["The specific actions or reactions of an organism that recur with a regularity more frequent than every 24 hours."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015734", "l": "taurine transport", "d": ["The directed movement of taurine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:2000407", "l": "regulation of T cell extravasation", "d": ["Any process that modulates the frequency, rate or extent of T cell extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000913", "l": "negative regulation of galactoglucomannan catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of galactoglucomannan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902349", "l": "response to chloroquine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009854", "l": "oxidative photosynthetic carbon pathway", "d": ["The reactions of the C2 pathway bring about the metabolic conversion of two molecules of 2-phosphoglycolate to one molecule of 3-phosphoglycerate, which can be used by the C3 cycle, and one molecule of carbon dioxide (CO2)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902390", "l": "regulation of N-terminal peptidyl-serine acetylation", "d": ["Any process that modulates the frequency, rate or extent of N-terminal peptidyl-serine acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036390", "l": "pre-replicative complex assembly involved in bacterial-type DNA replication", "d": ["The aggregation, arrangement and bonding together of a set of components to form the bacterial pre-replicative complex, a protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.905555711669919", "identifiers": [{"i": "GO:0062207", "l": "regulation of pattern recognition receptor signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of a pattern recognition receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051769", "l": "regulation of nitric-oxide synthase biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904088", "l": "positive regulation of epiboly involved in gastrulation with mouth forming second", "d": ["Any process that activates or increases the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902277", "l": "negative regulation of pancreatic amylase secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic amylase secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046830", "l": "positive regulation of RNA import into nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of movement of RNA from the cytoplasm into the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001291", "l": "codeine metabolic process", "d": ["The chemical reactions and pathways involving codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001136", "l": "negative regulation of endocytic recycling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endocytic recycling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0023059", "l": "positive adaptation of signaling pathway", "d": ["The positive regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071468", "l": "cellular response to acidic pH", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007260", "l": "tyrosine phosphorylation of STAT protein", "d": ["The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.465174152298118", "identifiers": [{"i": "GO:0035265", "l": "organ growth", "d": ["The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:0031123", "l": "RNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of an RNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010688", "l": "negative regulation of ribosomal protein gene transcription by RNA polymerase II", "d": ["Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903983", "l": "positive regulation of microvillus length", "d": ["A process that increases the length of a microvillus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035795", "l": "negative regulation of mitochondrial membrane permeability", "d": ["Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002121", "l": "inter-male aggressive behavior", "d": ["Aggressive behavior based on competition between males of the same species over access to resources such as females, dominance, status, etc. and characterized by noise, threats, and is often less injurious."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:1902369", "l": "negative regulation of RNA catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900358", "l": "negative regulation of nigerotriose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nigerotriose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003340", "l": "negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "d": ["Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1990438", "l": "U6 2'-O-snRNA methylation", "d": ["The posttranscriptional addition a methyl group to the 2'-oxygen atom of a nucleotide residue in an U6 snRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0008587", "l": "imaginal disc-derived wing margin morphogenesis", "d": ["The process in which the anatomical structures of the imaginal disc-derived wing margin are generated and organized. The wing margin is a strip of cells in the third instar disc at the boundary between the presumptive dorsal and ventral surfaces of the wing blade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006147", "l": "guanine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030578", "l": "PML body organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of PML bodies, a class of nuclear body; they react against SP100 auto-antibodies (PML = promyelocytic leukemia)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045598", "l": "regulation of fat cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of adipocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0000394", "l": "RNA splicing, via endonucleolytic cleavage and ligation", "d": ["Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060519", "l": "cell adhesion involved in prostatic bud elongation", "d": ["The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the elongation of the primary prostatic bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0007351", "l": "tripartite regional subdivision", "d": ["Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002497", "l": "proteasomal proteolysis associated with antigen processing and presentation", "d": ["The hydrolysis of a peptide bond or bonds within a protein by the proteasome complex contributing to antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.004905482618113", "identifiers": [{"i": "GO:0000281", "l": "mitotic cytokinesis", "d": ["A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0072160", "l": "nephron tubule epithelial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000519", "l": "positive regulation of T-helper 1 cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 1 cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.155424086811493", "identifiers": [{"i": "GO:0030638", "l": "polyketide metabolic process", "d": ["The chemical reactions and pathways involving polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0072038", "l": "mesenchymal stem cell maintenance involved in nephron morphogenesis", "d": ["The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903212", "l": "protein localization to mating-type region heterochromatin", "d": ["A process in which a protein is transported to, or maintained in, a location within a mating-type region heterochromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0043405", "l": "regulation of MAP kinase activity", "d": ["Any process that modulates the frequency, rate or extent of MAP kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0098610", "l": "adhesion between unicellular organisms", "d": ["The attachment of two unicellular organisms to each other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0032604", "l": "granulocyte macrophage colony-stimulating factor production", "d": ["The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002648", "l": "positive regulation of central tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of central tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.983606478119093", "identifiers": [{"i": "GO:0002504", "l": "antigen processing and presentation of peptide or polysaccharide antigen via MHC class II", "d": ["The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036152", "l": "phosphatidylethanolamine acyl-chain remodeling", "d": ["Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902699", "l": "pentose catabolic process to acetate", "d": ["The chemical reactions and pathways resulting in the breakdown of pentose to acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018009", "l": "N-terminal peptidyl-L-cysteine N-palmitoylation", "d": ["The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal cysteine residue to form N-palmitoyl-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903881", "l": "regulation of interleukin-17-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of interleukin-17-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060934", "l": "His-Purkinje system cell fate commitment", "d": ["The commitment of cells to His-Purkinje cell fates and their capacity to differentiate into His-Purkinje cells. These cells form the fibers that regulate cardiac muscle contraction in the ventricles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901738", "l": "regulation of vitamin A metabolic process", "d": ["Any process that modulates the frequency, rate or extent of vitamin A metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031044", "l": "O-glycan processing, core 8", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 8 O-glycan structure, Gal-alpha-(1->3)-GalNAc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160068", "l": "negative regulation of pollen tube guidance", "d": ["Any process that decreases the rate, frequency or extent of pollen tube guidance towards ovules. This is one mechanism to prevent polytuby, the simultaneous penetration of ovules by multiple pollen tubes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072103", "l": "glomerulus vasculature morphogenesis", "d": ["The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904716", "l": "positive regulation of chaperone-mediated autophagy", "d": ["Any process that activates or increases the frequency, rate or extent of chaperone-mediated autophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904136", "l": "regulation of convergent extension involved in notochord morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of convergent extension involved in notochord morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.936889416732384", "identifiers": [{"i": "GO:0051726", "l": "regulation of cell cycle", "d": ["Any process that modulates the rate or extent of progression through the cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035133", "l": "post-embryonic caudal fin morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905642", "l": "negative regulation of DNA methylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA methylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019483", "l": "beta-alanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900267", "l": "positive regulation of substance P receptor binding", "d": ["Any process that activates or increases the frequency, rate or extent of substance P receptor binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.161881760686384", "identifiers": [{"i": "GO:0002687", "l": "positive regulation of leukocyte migration", "d": ["Any process that activates or increases the frequency, rate, or extent of leukocyte migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0043482", "l": "cellular pigment accumulation", "d": ["The aggregation of coloring matter in a particular location in a cell, occurring in response to some external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070607", "l": "regulation of cell wall (1->3)-alpha-glucan metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000123", "l": "positive regulation of stomatal complex development", "d": ["Any process that activates or increases the frequency, rate or extent of stomatal complex development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030419", "l": "nicotianamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048789", "l": "cytoskeletal matrix organization at active zone", "d": ["The assembly and arrangement of cytomatrix proteins to form complexes in the cell cortex beneath the active zone, i.e. just beneath the presynaptic plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048480", "l": "stigma development", "d": ["The process whose specific outcome is the progression of the stigma over time, from its formation to the mature structure. The stigma is the pollen-receptive surface of a carpel or group of fused carpels, usually sticky."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2000771", "l": "positive regulation of establishment or maintenance of cell polarity regulating cell shape", "d": ["Any process that activates or increases the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905399", "l": "regulation of activated CD4-positive, alpha-beta T cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904056", "l": "positive regulation of cholangiocyte proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0032119", "l": "sequestering of zinc ion", "d": ["The process of binding or confining zinc ions such that they are separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904878", "l": "negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046048", "l": "UDP metabolic process", "d": ["The chemical reactions and pathways involving UDP, uridine (5'-)diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901947", "l": "5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate metabolic process", "d": ["The chemical reactions and pathways involving 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0010559", "l": "regulation of glycoprotein biosynthetic process", "d": ["Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902928", "l": "inulin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of inulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904719", "l": "positive regulation of AMPA glutamate receptor clustering", "d": ["Any process that activates or increases the frequency, rate or extent of AMPA glutamate receptor clustering."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002914", "l": "regulation of central B cell anergy", "d": ["Any process that modulates the frequency, rate, or extent of central B cell anergy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901761", "l": "oxytetracycline metabolic process", "d": ["The chemical reactions and pathways involving oxytetracycline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048721", "l": "clypeus morphogenesis", "d": ["The process in which the anatomical structures of the clypeus are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010133", "l": "proline catabolic process to glutamate", "d": ["The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including glutamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.112122362005948", "identifiers": [{"i": "GO:0030902", "l": "hindbrain development", "d": ["The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901692", "l": "regulation of compound eye retinal cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0001865", "l": "NK T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a NK T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0140718", "l": "facultative heterochromatin formation", "d": ["The compaction of chromatin into a conformation that is refactory to transcription but that be converted to euchromatin and allow transcription in specific contexts. These can be temporal (e.g., developmental states or specific cell-cycle stages), spatial (e.g., nuclear localization changes from the center to the periphery or vice versa due to exogenous factors/signals), or parental/heritable (e.g., monoallelic gene expression)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072356", "l": "chromosome passenger complex localization to kinetochore", "d": ["A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003026", "l": "regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback", "d": ["The process that modulates blood pressure by sensing the amount of stretch occurring in the aorta and responding to the input via central nervous system control."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902891", "l": "negative regulation of root hair elongation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of root hair elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:1903664", "l": "regulation of asexual reproduction", "d": ["Any process that modulates the frequency, rate or extent of asexual reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019648", "l": "formaldehyde assimilation via xylulose monophosphate cycle", "d": ["The pathway in which formaldehyde is used as a carbon source in the xylulose monophosphate cycle. Methylotrophic yeasts, but not bacteria, utilize the xylulose monophosphate cycle to fix formaldehyde and convert it into metabolically useful organic compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0061389", "l": "regulation of direction of cell growth", "d": ["Any process that modulates the direction of cell growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014713", "l": "negative regulation of branchiomeric skeletal muscle development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060832", "l": "oocyte animal/vegetal axis specification", "d": ["The establishment, maintenance and elaboration of the animal/vegetal axis in the oocyte. The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. The pole of the egg that is closest to the nucleus defines the animal end, with the axis passing through the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903660", "l": "negative regulation of complement-dependent cytotoxicity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of complement-dependent cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071380", "l": "cellular response to prostaglandin E stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.116918913335823", "identifiers": [{"i": "GO:0070663", "l": "regulation of leukocyte proliferation", "d": ["Any process that modulates the frequency, rate or extent of leukocyte proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:1990138", "l": "neuron projection extension", "d": ["Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902058", "l": "regulation of sporocarp development involved in sexual reproduction", "d": ["Any process that modulates the frequency, rate or extent of sporocarp development involved in sexual reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010781", "l": "meiotic DNA double-strand break formation involved in meiotic gene conversion", "d": ["The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035831", "l": "palmatine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of palmatine, a berberine alkaloid found in many plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901491", "l": "negative regulation of lymphangiogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051330", "l": "meiotic G1 phase", "d": ["The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by meiosis and the beginning of DNA synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051472", "l": "glucosylglycerol metabolic process", "d": ["The chemical reactions and pathways involving glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097692", "l": "histone H3-K4 monomethylation", "d": ["The modification of histone H3 by addition of one methyl group to lysine at position 4 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042883", "l": "cysteine transport", "d": ["The directed movement of cysteine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901823", "l": "delta-carotene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of delta-carotene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018343", "l": "protein farnesylation", "d": ["The covalent attachment of a farnesyl group to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048642", "l": "negative regulation of skeletal muscle tissue development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.780700721499244", "identifiers": [{"i": "GO:0006826", "l": "iron ion transport", "d": ["The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035977", "l": "protein deglycosylation involved in glycoprotein catabolic process", "d": ["The removal of sugar residues from a glycosylated protein that contributes to the breakdown of a glycoprotein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031860", "l": "telomeric 3' overhang formation", "d": ["The formation of the single stranded telomeric 3' overhang, a conserved feature that ranges in length from 12 nt in budding yeast to approximately 500 nt in humans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060542", "l": "regulation of strand invasion", "d": ["Any process that modulates the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0000320", "l": "re-entry into mitotic cell cycle", "d": ["The resumption of the mitotic cell division cycle by cells that were in a quiescent or other non-dividing state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900554", "l": "asperfuranone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of asperfuranone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0140238", "l": "presynaptic endocytosis", "d": ["A vesicle-mediated transport process in which the presynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0061512", "l": "protein localization to cilium", "d": ["A process in which a protein is transported to, or maintained in, a location within a cilium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990559", "l": "mitochondrial coenzyme A transmembrane transport", "d": ["The process in which coenzyme A is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0021511", "l": "spinal cord patterning", "d": ["The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016340", "l": "calcium-dependent cell-matrix adhesion", "d": ["The binding of a cell to the extracellular matrix via adhesion molecules that require the presence of calcium for the interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904675", "l": "regulation of somatic stem cell division", "d": ["Any process that modulates the frequency, rate or extent of somatic stem cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032322", "l": "ubiquinone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ubiquinone, a lipid-soluble electron-transporting coenzyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014884", "l": "detection of muscle inactivity involved in regulation of muscle adaptation", "d": ["The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000544", "l": "regulation of endothelial cell chemotaxis to fibroblast growth factor", "d": ["Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021504", "l": "neural fold hinge point formation", "d": ["The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009865", "l": "pollen tube adhesion", "d": ["The process in which the pollen tube adheres to cells of the stigma and style."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.281967957033203", "identifiers": [{"i": "GO:0097746", "l": "blood vessel diameter maintenance", "d": ["Any process that modulates the diameter of blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0071415", "l": "cellular response to purine-containing compound", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905667", "l": "negative regulation of protein localization to endosome", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043251", "l": "sodium-dependent organic anion transport", "d": ["The directed, sodium-dependent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900016", "l": "negative regulation of cytokine production involved in inflammatory response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006049", "l": "UDP-N-acetylglucosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0015961", "l": "diadenosine polyphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902081", "l": "negative regulation of calcium ion import into sarcoplasmic reticulum", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097532", "l": "stress response to acid chemical", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902457", "l": "negative regulation of stomatal opening", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of stomatal opening."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099553", "l": "trans-synaptic signaling by endocannabinoid, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, via the release and reception of endocannabinoid ligands, that modulates the synaptic transmission properties of the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015763", "l": "N-acetylgalactosamine transport", "d": ["The directed movement of N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018321", "l": "protein glucuronylation", "d": ["The modification of a protein by amino acid glucuronylation, the addition of a glucuronate group, the uronic acid derived from glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0086005", "l": "ventricular cardiac muscle cell action potential", "d": ["An action potential that occurs in a ventricular cardiac muscle cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0007135", "l": "meiosis II", "d": ["The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010932", "l": "regulation of macrophage tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of macrophage tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0030224", "l": "monocyte differentiation", "d": ["The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1901021", "l": "positive regulation of calcium ion transmembrane transporter activity", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014748", "l": "negative regulation of tonic skeletal muscle contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of tonic skeletal muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902922", "l": "poly(3-hydroxyvalerate) metabolic process", "d": ["The chemical reactions and pathways involving poly(3-hydroxyvalerate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045653", "l": "negative regulation of megakaryocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035144", "l": "anal fin morphogenesis", "d": ["The process in which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904348", "l": "negative regulation of small intestine smooth muscle contraction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042482", "l": "positive regulation of odontogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905065", "l": "positive regulation of vascular associated smooth muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140285", "l": "endosome fission", "d": ["The process by which early and late endosomes undergo budding and fission reactions that separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072068", "l": "late distal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002904", "l": "positive regulation of B cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060752", "l": "intestinal phytosterol absorption", "d": ["Any process in which phytosterols are taken up from the contents of the intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090138", "l": "regulation of actin cytoskeleton organization by cell-cell adhesion", "d": ["Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032237", "l": "activation of store-operated calcium channel activity", "d": ["A process that initiates the activity of an inactive store-operated calcium channel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051549", "l": "positive regulation of keratinocyte migration", "d": ["Any process that activates or increases the frequency, rate or extent of keratinocyte migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045752", "l": "positive regulation of Toll signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the Tl signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044805", "l": "late nucleophagy", "d": ["A type of nucleophagy, distinct from piecemeal microautophagy of the nucleus (PNM) where the nuclear material is delivered to the vacuole/lysosome for breakdown and recycling later than observed for PNM."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000038", "l": "regulation of stomatal complex development", "d": ["Any process that modulates the frequency, rate or extent of stomatal complex development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001804", "l": "negative regulation of type III hypersensitivity", "d": ["Any process that stops, prevents, or reduces the rate of type III hypersensitivity, a type of inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901028", "l": "regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000333", "l": "negative regulation of blood microparticle formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of blood microparticle formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048654", "l": "anther morphogenesis", "d": ["The process in which the anatomical structures of the anther are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140972", "l": "negative regulation of AIM2 inflammasome complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of AIM2 inflammasome complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042038", "l": "peptidyl-histidine methylation, to form tele-methylhistidine", "d": ["The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904749", "l": "regulation of protein localization to nucleolus", "d": ["Any process that modulates the frequency, rate or extent of protein localization to nucleolus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902696", "l": "glycine catabolic process to isobutanol", "d": ["The chemical reactions and pathways resulting in the breakdown of glycine to isobutanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033023", "l": "mast cell homeostasis", "d": ["The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035070", "l": "salivary gland histolysis", "d": ["The stage-specific break down of the larval salivary glands during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0090558", "l": "plant epidermis development", "d": ["The process whose specific outcome is the progression of the plant epidermis over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061888", "l": "regulation of astrocyte activation", "d": ["Any process that modulates the frequency, rate or extent of astrocyte activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075503", "l": "fusion of virus membrane with host macropinosome membrane", "d": ["Fusion of a viral membrane with a host macropinosome membrane, that occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents into the host cell cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035526", "l": "retrograde transport, plasma membrane to Golgi", "d": ["The directed movement of substances from the plasma membrane back to the trans-Golgi network, mediated by vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071800", "l": "podosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a podosome, an actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.232064878529073", "identifiers": [{"i": "GO:0043393", "l": "regulation of protein binding", "d": ["Any process that modulates the frequency, rate or extent of protein binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045315", "l": "positive regulation of compound eye photoreceptor development", "d": ["Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002558", "l": "type I hypersensitivity mediated by mast cells", "d": ["An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003033", "l": "detection of hypoxic conditions in blood by aortic body chemoreceptor signaling", "d": ["The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the aortic bodies."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141026", "l": "adhesion of symbiont to host cell surface via host membrane cholesterol", "d": ["The attachment of a symbiont to its host by binding to cholesterol on the host cell surface. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1990089", "l": "response to nerve growth factor", "d": ["A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019715", "l": "peptidyl-aspartic acid hydroxylation to form L-erythro-beta-hydroxyaspartic acid", "d": ["The hydroxylation of peptidyl-aspartic acid to form peptidyl-L-erythro-beta-hydroxyaspartic acid; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019371", "l": "cyclooxygenase pathway", "d": ["The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051941", "l": "regulation of amino acid uptake involved in synaptic transmission", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001306", "l": "lipoxin B4 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000328", "l": "regulation of T-helper 17 cell lineage commitment", "d": ["Any process that modulates the frequency, rate or extent of T-helper 17 cell lineage commitment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106036", "l": "assembly of apicomedial cortex actomyosin", "d": ["A process which results in the assembly or arrangement of constituent parts apicomedial cortex actomyosin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0060048", "l": "cardiac muscle contraction", "d": ["Muscle contraction of cardiac muscle tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1904683", "l": "regulation of metalloendopeptidase activity", "d": ["Any process that modulates the frequency, rate or extent of metalloendopeptidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045107", "l": "intermediate filament polymerization", "d": ["Assembly of intermediate filaments by the addition of component monomers to a filament. Polymerization of intermediate filament proteins results from interactions among several distinct binding sites on the constituent proteins. Nuclear lamin head-to-tail polymers arise from one such interaction. Deletion analysis localized the binding sites to the ends of the rod domain that are highly conserved among all intermediate filament proteins. Data indicate that one type of interaction in intermediate filament protein polymerization is the longitudinal binding of dimers via the conserved end segments of the coiled-coil rod domain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902550", "l": "lymphoid lineage cell migration into thymus involved in thymus epithelium morphogenesis", "d": ["Any lymphoid lineage cell migration into thymus that is involved in thymus epithelium morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140291", "l": "peptidyl-glutamate ADP-deribosylation", "d": ["The removal of ADP-ribose from ADP-ribosylglutamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090250", "l": "cell-cell adhesion involved in establishment of planar polarity", "d": ["The attachment of one cell to another cell via adhesion molecules that contributes to the establishment of planar cell polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021623", "l": "oculomotor nerve formation", "d": ["The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900631", "l": "tridecane metabolic process", "d": ["The chemical reactions and pathways involving tridecane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035143", "l": "caudal fin morphogenesis", "d": ["The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045210", "l": "FasL biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fas ligand (FasL or CD95L), an antigen originally found to be expressed on the cell surface of activated human T-lymphocytes and B-lymphocytes and a variety of malignant human lymphoid cell lines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "47.949658210835416", "identifiers": [{"i": "GO:0007268", "l": "chemical synaptic transmission", "d": ["The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018250", "l": "peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine", "d": ["The formation of peptidyl-dehydroalanine from either peptidyl-tyrosine by phenyl transfer, or from peptidyl-serine, which is coupled with the formation of 5-imidazolinone by the two neighboring residues, produces an 4-methylidene-imidazole-5-one active site of some amino acid ammonia-lyases; the 4-methylidene-imidazole-5-one, is formed autocatalytically by cyclization and dehydration of the sequence ASG."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140732", "l": "positive regulation of amphiregulin production", "d": ["Any process that activates or increases the frequency, rate or extent of production of amphiregulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.314728742240533", "identifiers": [{"i": "GO:0051169", "l": "nuclear transport", "d": ["The directed movement of substances into, out of, or within the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.415093686714229", "identifiers": [{"i": "GO:0045664", "l": "regulation of neuron differentiation", "d": ["Any process that modulates the frequency, rate or extent of neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0100001", "l": "regulation of skeletal muscle contraction by action potential", "d": ["Any action potential process that regulates skeletal muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902634", "l": "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0032297", "l": "negative regulation of DNA-templated DNA replication initiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070248", "l": "negative regulation of natural killer cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell death by apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0001976", "l": "nervous system process involved in regulation of systemic arterial blood pressure", "d": ["The regulation of blood pressure mediated by detection of stimuli and a neurological response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106396", "l": "regulation of R7 cell fate commitment", "d": ["Any process that modulates the frequency, rate or extent of R7 cell fate commitment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034148", "l": "negative regulation of toll-like receptor 5 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 5 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000524", "l": "negative regulation of T cell costimulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T cell costimulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902088", "l": "plant-type cell wall loosening involved in abscission", "d": ["Any plant-type cell wall loosening that is involved in abscission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007111", "l": "meiosis II cytokinesis", "d": ["A cell cycle process that results in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0098512", "l": "detection of humidity stimulus involved in sensory perception", "d": ["The series of events in which a humidity stimulus is received and converted into a molecular signal as part of the sensory perception of humidity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0016037", "l": "light absorption", "d": ["The reception of a photon by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042939", "l": "tripeptide transport", "d": ["The directed movement of a tripeptide, a compound containing three amino acids linked together by peptide bonds, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150094", "l": "amyloid-beta clearance by cellular catabolic process", "d": ["The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by intracellular degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0007136", "l": "meiotic prophase II", "d": ["The cell cycle phase which is the first stage of meiosis II and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006157", "l": "deoxyadenosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0035306", "l": "positive regulation of dephosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048759", "l": "xylem vessel member cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a vessel member cell. A vessel member cell is one of the components of a vessel in the xylem. It is a dead cell with the wall between adjacent members being variously perforated and the walls that persist variously thickened."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:0045190", "l": "isotype switching", "d": ["The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090161", "l": "Golgi ribbon formation", "d": ["The formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.142364941642427", "identifiers": [{"i": "GO:0045132", "l": "meiotic chromosome segregation", "d": ["The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901725", "l": "regulation of histone deacetylase activity", "d": ["Any process that modulates the frequency, rate or extent of histone deacetylase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060354", "l": "negative regulation of cell adhesion molecule production", "d": ["Any process that decreases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901865", "l": "capsorubin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of capsorubin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.63194463958741", "identifiers": [{"i": "GO:0034250", "l": "positive regulation of amide metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905585", "l": "regulation of outer hair cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of outer hair cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900074", "l": "negative regulation of neuromuscular synaptic transmission", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0048466", "l": "androecium development", "d": ["The process whose specific outcome is the progression of the androecium over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0052319", "l": "regulation of phytoalexin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0110028", "l": "positive regulation of mitotic spindle organization", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic spindle organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019422", "l": "disproportionation of elemental sulfur", "d": ["The process in which sulfur compounds with an intermediate oxidation state serve as both electron donors and electron acceptors in an energy-generating redox process. The reaction takes place anaerobically, in light and in the absence of CO2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034606", "l": "response to hermaphrodite contact", "d": ["The response by the male to a hermaphrodite after initial contact following mate finding. The male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061582", "l": "intestinal epithelial cell migration", "d": ["The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032985", "l": "protein-carbohydrate complex disassembly", "d": ["The disaggregation of a protein-carbohydrate complex into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010025", "l": "wax biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of wax, which includes C16 and C18 fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0072109", "l": "glomerular mesangium development", "d": ["The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021637", "l": "trigeminal nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900969", "l": "negative regulation of sarcinapterin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006930", "l": "substrate-dependent cell migration, cell extension", "d": ["The formation of a cell surface protrusion, such as a lamellipodium or filopodium, at the leading edge of a migrating cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0002922", "l": "positive regulation of humoral immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of a humoral immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036187", "l": "cell growth mode switching, budding to filamentous", "d": ["The process in which a cell switches from growing as a round budding cell to growing as a filament (elongated cells attached end-to-end). An example of this is the yeast-hyphal transition of Candida albicans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900353", "l": "positive regulation of methanofuran biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of methanofuran biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072188", "l": "metanephric cap specification", "d": ["The process in which the metanephric cap acquires its identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900660", "l": "positive regulation of emericellamide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of emericellamide biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0009637", "l": "response to blue light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060269", "l": "centripetally migrating follicle cell migration", "d": ["The cell migration process in which a follicle cell migrates as part of an epithelial sheet between the nurse cells and the oocyte. At the end of migration, they cover the anterior of the oocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035106", "l": "operant conditioning", "d": ["Learning to anticipate future events on the basis of past experience with the consequences of one's own behavior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051949", "l": "negative regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035820", "l": "negative regulation of renal sodium excretion by angiotensin", "d": ["The process in which angiotensin decreases the amount of sodium that is excreted in urine over a unit of time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000128", "l": "regulation of octopamine signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of octopamine signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905696", "l": "regulation of polysome binding", "d": ["Any process that modulates the frequency, rate or extent of polysome binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014883", "l": "transition between fast and slow fiber", "d": ["The process of conversion of fast-contracting muscle fibers to a slower character. This may involve slowing of contractile rate, slow myosin gene induction, increase in oxidative metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048377", "l": "lateral mesodermal cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901996", "l": "regulation of indoleacetic acid biosynthetic process via tryptophan", "d": ["Any process that modulates the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905279", "l": "regulation of retrograde transport, endosome to Golgi", "d": ["Any process that modulates the frequency, rate or extent of retrograde transport, endosome to Golgi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900753", "l": "doxorubicin transport", "d": ["The directed movement of a doxorubicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060310", "l": "regulation of elastin catabolic process", "d": ["Any process that modulates the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903031", "l": "regulation of microtubule plus-end binding", "d": ["Any process that modulates the frequency, rate or extent of microtubule plus-end binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904894", "l": "positive regulation of receptor signaling pathway via STAT", "d": ["Any process that activates or increases the frequency, rate or extent of receptor signaling pathway via STAT."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018920", "l": "glyphosate metabolic process", "d": ["The chemical reactions and pathways involving glyphosate, a broad-spectrum herbicide also known by the trade name Roundup. It is a member of a broad class of compounds known as phosphonic acids, which contain a direct carbon-to-phosphorus (C-P) bond."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035247", "l": "peptidyl-arginine omega-N-methylation", "d": ["The addition of a methyl group onto a terminal nitrogen (omega nitrogen) atom of an arginine residue in a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002298", "l": "CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response", "d": ["The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048629", "l": "trichome patterning", "d": ["The regionalization process of establishing the non-random spatial arrangement of trichomes on the surface and margin of a leaf. Process involves signaling between adjacent epidermal cells that results in differentiation of some epidermal cells into trichomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060616", "l": "mammary gland cord formation", "d": ["The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000115", "l": "regulation of maintenance of bipolar cell polarity regulating cell shape", "d": ["Any process that modulates the frequency, rate or extent of maintenance of bipolar cell polarity regulating in cell shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000637", "l": "positive regulation of miRNA-mediated gene silencing", "d": ["A process that activates or increases the frequency, rate or extent of gene silencing by a microRNA (miRNA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031553", "l": "positive regulation of brain-derived neurotrophic factor-activated receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072720", "l": "response to dithiothreitol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033512", "l": "L-lysine catabolic process to acetyl-CoA via saccharopine", "d": ["The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate saccharopine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000063", "l": "positive regulation of ureter smooth muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.287337192553075", "identifiers": [{"i": "GO:0010605", "l": "negative regulation of macromolecule metabolic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048219", "l": "inter-Golgi cisterna vesicle-mediated transport", "d": ["The directed movement of substances from one Golgi cisterna to another, mediated by small transport vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905871", "l": "regulation of protein localization to cell leading edge", "d": ["Any process that modulates the frequency, rate or extent of protein localization to cell leading edge."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141010", "l": "retrotransposon silencing by RNA-directed DNA methylation", "d": ["A retrotransposon silencing mechanism mediated by RNA-directed DNA methylation. RNA-directed DNA methylation is a gene silencing process in which small interfering RNAs (siRNAs) guide DNA methylation to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0030243", "l": "cellulose metabolic process", "d": ["The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900584", "l": "o-orsellinic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of o-orsellinic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060270", "l": "main body follicle cell migration", "d": ["The ovarian follicle cell migration process in which follicle cells migrate posteriorly to form a columnar epithelium over the oocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070086", "l": "ubiquitin-dependent endocytosis", "d": ["Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010144", "l": "pyridoxal phosphate biosynthetic process from pyridoxamine", "d": ["The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, the active form of vitamin B6, from pyridoxamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0002063", "l": "chondrocyte development", "d": ["The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090194", "l": "negative regulation of glomerulus development", "d": ["Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0035218", "l": "leg disc development", "d": ["Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035139", "l": "pelvic fin morphogenesis", "d": ["The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904218", "l": "negative regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035129", "l": "post-embryonic hindlimb morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the hindlimb are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044858", "l": "plasma membrane raft polarization", "d": ["The clustering and aggregation of a plasma membrane into domains. This serves as a mechanism to compartmentalize cellular activities and to establish cell polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901458", "l": "negative regulation of response to acetate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904760", "l": "regulation of myofibroblast differentiation", "d": ["Any process that modulates the frequency, rate or extent of myofibroblast differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905584", "l": "outer hair cell apoptotic process", "d": ["Any apoptotic process in an outer hair cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042919", "l": "benzoate transport", "d": ["The directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0048369", "l": "lateral mesoderm morphogenesis", "d": ["The process in which the anatomical structures of the lateral mesoderm are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030497", "l": "fatty acid elongation", "d": ["The elongation of a fatty acid chain by the sequential addition of two-carbon units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002075", "l": "somitomeric trunk muscle development", "d": ["The process whose specific outcome is the progression of the somitomeric trunk muscle over time, from its formation to the mature structure. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0062099", "l": "negative regulation of programmed necrotic cell death", "d": ["Any process that decreases the frequency, rate or extent of programmed necrotic cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990113", "l": "RNA polymerase I assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase I complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.805366613539277", "identifiers": [{"i": "GO:0000904", "l": "cell morphogenesis involved in differentiation", "d": ["The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.527781272052167", "identifiers": [{"i": "GO:1903037", "l": "regulation of leukocyte cell-cell adhesion", "d": ["Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070501", "l": "poly-gamma-glutamate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0002427", "l": "mucosal tolerance induction", "d": ["Tolerance induction taking place in the mucosal tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900506", "l": "regulation of iron-sulfur-molybdenum cofactor assembly", "d": ["Any process that modulates the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0033135", "l": "regulation of peptidyl-serine phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900646", "l": "regulation of chanoclavine-I aldehyde biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0008228", "l": "opsonization", "d": ["The process in which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008364", "l": "pupal chitin-based cuticle development", "d": ["Synthesis and deposition of a chitin-based pupal cuticle. At the end of the prepupal period the insect is covered by the pupal cuticle which continues to be elaborated into the pupal period. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:1902653", "l": "secondary alcohol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of secondary alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043001", "l": "Golgi to plasma membrane protein transport", "d": ["The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060287", "l": "epithelial cilium movement involved in determination of left/right asymmetry", "d": ["The movement of cilia of epithelial cells of the Left Right Organizer (LRO), also referred to as the node in mouse or the Kupffer's vesicle in zebrafish, resulting in the leftward fluid flow across the LRO and generation or transport of a signal which determines asymmetry in an organism's body plan with respect to the left and right halves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0034117", "l": "erythrocyte aggregation", "d": ["The adhesion of one erythrocyte to one or more other erythrocytes via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035166", "l": "post-embryonic hemopoiesis", "d": ["The stages of blood cell formation that take place after completion of embryonic development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003370", "l": "cell-cell adhesion involved in mesendodermal cell migration", "d": ["The attachment of mesendodermal cells to each other that contributes to the establishment of cell polarity that is part of the directed movement of the cells of the mesendoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034413", "l": "ascospore wall (1->3)-beta-D-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904416", "l": "negative regulation of xenophagy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of xenophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007298", "l": "border follicle cell migration", "d": ["The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010299", "l": "detoxification of cobalt ion", "d": ["Any process that reduces or removes the toxicity of cobalt ion. These include transport of cobalt away from sensitive areas and to compartments or complexes whose purpose is sequestration of cobalt ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010351", "l": "lithium ion transport", "d": ["The directed movement of lithium ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006020", "l": "inositol metabolic process", "d": ["The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071657", "l": "positive regulation of granulocyte colony-stimulating factor production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of granulocyte colony-stimulating factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904228", "l": "positive regulation of glycogen synthase activity, transferring glucose-1-phosphate", "d": ["Any process that activates or increases the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043288", "l": "apocarotenoid metabolic process", "d": ["The chemical reactions and pathways involving apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048730", "l": "epidermis morphogenesis", "d": ["The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902189", "l": "2-methylbutanoyl-CoA(4-) metabolic process", "d": ["The chemical reactions and pathways involving 2-methylbutanoyl-CoA(4-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045773", "l": "positive regulation of axon extension", "d": ["Any process that activates or increases the frequency, rate or extent of axon extension."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0009629", "l": "response to gravity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140698", "l": "attachment of telomeric heterochromatin to nuclear envelope", "d": ["The process in which physical connections are formed between sub-telomeric heterochromatin and the nuclear envelope facilitating bouquet formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900810", "l": "helvolic acid metabolic process", "d": ["The chemical reactions and pathways involving helvolic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0071922", "l": "regulation of cohesin loading", "d": ["Any process that modulates the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003234", "l": "bulbus arteriosus formation", "d": ["The developmental process pertaining to the initial formation of the bulbus arteriosus from unspecified parts. The bulbus arteriosus is an elastic chamber of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010925", "l": "positive regulation of inositol-polyphosphate 5-phosphatase activity", "d": ["Any process that increases the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006601", "l": "creatine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, most creatine is transported to and used in muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070961", "l": "positive regulation of neutrophil mediated killing of symbiont cell", "d": ["Any process that increases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2001228", "l": "regulation of response to gamma radiation", "d": ["Any process that modulates the frequency, rate or extent of response to gamma radiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903456", "l": "positive regulation of androst-4-ene-3,17-dione biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019703", "l": "coenzyme A-peptidyl-cysteine covalent linking", "d": ["The covalent linkage of coenzyme A and peptidyl-cysteine to form L-cysteine coenzyme A disulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0000436", "l": "carbon catabolite activation of transcription from RNA polymerase II promoter", "d": ["Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0060897", "l": "neural plate regionalization", "d": ["The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044660", "l": "viral release via pore formation in host cell membrane", "d": ["The dissemination of mature viral particles from a host cell via the formation by the virus of pores in its host cell membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905493", "l": "regulation of G-quadruplex DNA binding", "d": ["Any process that modulates the frequency, rate or extent of G-quadruplex DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070935", "l": "3'-UTR-mediated mRNA stabilization", "d": ["An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033184", "l": "positive regulation of histone ubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of the addition of a ubiquitin group to a histone protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.892466024748572", "identifiers": [{"i": "GO:1903039", "l": "positive regulation of leukocyte cell-cell adhesion", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007042", "l": "lysosomal lumen acidification", "d": ["Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045965", "l": "negative regulation of ecdysteroid metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070789", "l": "metula development", "d": ["The process whose specific outcome is the progression of metulae over time, from its formation to the mature structure. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.330951936344348", "identifiers": [{"i": "GO:0046474", "l": "glycerophospholipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009971", "l": "anastral spindle assembly involved in male meiosis", "d": ["The aggregation, arrangement and bonding together of a set of components to form the anastral spindle in male meiotic cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.187403162058388", "identifiers": [{"i": "GO:0002444", "l": "myeloid leukocyte mediated immunity", "d": ["Any process involved in the carrying out of an immune response by a myeloid leukocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0034284", "l": "response to monosaccharide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140623", "l": "type I pilus assembly", "d": ["The assembly from its constituent parts of a type I pilus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046263", "l": "nitrotoluene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nitrotoluene, any methylbenzene molecule with NO2 group(s) attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901460", "l": "regulation of response to formic acid", "d": ["Any process that modulates the frequency, rate or extent of response to formic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904361", "l": "positive regulation of spore germination", "d": ["Any process that activates or increases the frequency, rate or extent of spore germination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900942", "l": "negative regulation of (Z)-nonadeca-1,14-diene biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097011", "l": "cellular response to granulocyte macrophage colony-stimulating factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905157", "l": "positive regulation of photosynthesis", "d": ["Any process that activates or increases the frequency, rate or extent of photosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071548", "l": "response to dexamethasone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061083", "l": "regulation of protein refolding", "d": ["Any process that regulates the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904253", "l": "positive regulation of bile acid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of bile acid metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003055", "l": "circadian regulation of heart rate by the suprachiasmatic nucleus", "d": ["The process in which the suprachiasmatic nucleus modulates heart rate at different values with a regularity of approximately 24 hours."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071260", "l": "cellular response to mechanical stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048504", "l": "regulation of timing of animal organ formation", "d": ["Any process that modulates the rate, frequency or extent of animal organ formation at a consistent predetermined time point during development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.938643630768524", "identifiers": [{"i": "GO:0006261", "l": "DNA-templated DNA replication", "d": ["A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0031169", "l": "ferrichrome biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032088", "l": "negative regulation of NF-kappaB transcription factor activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901321", "l": "positive regulation of heart induction", "d": ["Any process that activates or increases the frequency, rate or extent of heart induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990487", "l": "anaerobic lignin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lignin in the absence of oxygen. Lignin is a class of polymers of phenylpropanoid units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061699", "l": "peptidyl-lysine deglutarylation", "d": ["The removal of a glutaryl group (CO-CH2-CH2--CH2-CO) from a glutarylated lysine residue in a peptide or protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046258", "l": "anaerobic 2,4,6-trinitrotoluene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904964", "l": "positive regulation of phytol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of phytol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060545", "l": "positive regulation of necroptotic process", "d": ["Any process that increases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006064", "l": "glucuronate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucuronate, any salt or ester of glucuronic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035161", "l": "imaginal disc lineage restriction", "d": ["Formation and/or maintenance of a lineage boundary between compartments in an imaginal disc that cells cannot cross, thus separating the populations of cells in each compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098715", "l": "malonic acid import across plasma membrane", "d": ["The directed movement of malonic acid from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.529191385365799", "identifiers": [{"i": "GO:0098655", "l": "monoatomic cation transmembrane transport", "d": ["The process in which a monoatomic cation is transported across a membrane. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035384", "l": "thioester biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032833", "l": "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036340", "l": "chitin-based cuticle sclerotization by biomineralization", "d": ["The process of hardening a chitin-based cuticle by mineral incorporation. For example, the cuticle of crustaceans is hardened by the incorporation of calcium carbonate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034299", "l": "reproductive blastospore formation", "d": ["The formation of a spore following the marked enlargement of part of a cell before separation by a septum. Blastospores are a type of asexual spore found in some fungi, most notably the class Glomeromycota."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900841", "l": "negative regulation of helvolic acid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of helvolic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904333", "l": "positive regulation of error-prone translesion synthesis", "d": ["Any process that activates or increases the frequency, rate or extent of error-prone translesion synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052035", "l": "positive regulation by symbiont of host inflammatory response", "d": ["Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015730", "l": "propanoate transmembrane transport", "d": ["The directed movement of propionate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097040", "l": "phthiocerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phthiocerol, a lipid-based 1,3-glycol consisting of (3S,4R)-3-methoxy-4-methylnonacosane having (9R)- and (11S)-hydroxy substituents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0140241", "l": "translation at synapse", "d": ["Translation that occurs at the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904048", "l": "regulation of spontaneous neurotransmitter secretion", "d": ["Any process that modulates the frequency, rate or extent of spontaneous neurotransmitter secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060647", "l": "mesenchymal cell condensation involved in mammary fat development", "d": ["The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140873", "l": "paxilline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of paxilline, a mycotoxin that acts as an inhibitor of mammalian maxi-K channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905698", "l": "positive regulation of polysome binding", "d": ["Any process that activates or increases the frequency, rate or extent of polysome binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033120", "l": "positive regulation of RNA splicing", "d": ["Any process that activates or increases the frequency, rate or extent of RNA splicing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1904385", "l": "cellular response to angiotensin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900606", "l": "tensidol B metabolic process", "d": ["The chemical reactions and pathways involving tensidol B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.5052627844751", "identifiers": [{"i": "GO:0061534", "l": "gamma-aminobutyric acid secretion, neurotransmission", "d": ["The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043496", "l": "regulation of protein homodimerization activity", "d": ["Any process that modulates the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048909", "l": "anterior lateral line nerve development", "d": ["The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904523", "l": "regulation of DNA amplification", "d": ["Any process that modulates the frequency, rate or extent of DNA amplification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003192", "l": "mitral valve formation", "d": ["The developmental process pertaining to the initial formation of the mitral valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048805", "l": "imaginal disc-derived genitalia morphogenesis", "d": ["The process in which the anatomical structures of genitalia are generated and organized from the genital imaginal disc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903764", "l": "regulation of potassium ion export across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of potassium ion export across the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002255", "l": "tissue kallikrein-kinin cascade", "d": ["A series of reactions that takes place outside the cell initiated by the action of tissue (glandular) kallikreins on low molecular weight kininogen in response to tissue damage. Tissue kallikreins are present in glandular tissues and their fluids, such as the salivary glands, sweat glands, pancreas, and kidney. The ultimate products of the tissue kallikrein-kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002282", "l": "microglial cell activation involved in immune response", "d": ["The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071210", "l": "protein insertion into membrane raft", "d": ["The process in which a protein is incorporated into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044747", "l": "pre-miRNA 3'-end processing", "d": ["Any process involved in forming distinct miRNA isoforms from a mature miRNA that differ at their 3'-ends."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009299", "l": "mRNA transcription", "d": ["The cellular synthesis of messenger RNA (mRNA) from a DNA template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0001825", "l": "blastocyst formation", "d": ["The initial formation of a blastocyst from a solid ball of cells known as a morula."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0048145", "l": "regulation of fibroblast proliferation", "d": ["Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903392", "l": "negative regulation of adherens junction organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of adherens junction organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0060900", "l": "embryonic camera-type eye formation", "d": ["The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0009142", "l": "nucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061251", "l": "mesonephric glomerular epithelial cell development", "d": ["The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903590", "l": "regulation of lysozyme activity", "d": ["Any process that modulates the frequency, rate or extent of lysozyme activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0035082", "l": "axoneme assembly", "d": ["The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901280", "l": "D-ribose 5-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-ribose 5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903341", "l": "regulation of meiotic DNA double-strand break formation", "d": ["Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019242", "l": "methylglyoxal biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051166", "l": "2,5-dihydroxypyridine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044358", "l": "envenomation resulting in hemorrhagic damage in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with vascular damage and hemorrhage in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:1902414", "l": "protein localization to cell junction", "d": ["A process in which a protein is transported to, or maintained in, a location within a cell junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.124646994401843", "identifiers": [{"i": "GO:0044772", "l": "mitotic cell cycle phase transition", "d": ["The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1902603", "l": "carnitine transmembrane transport", "d": ["The directed movement of carnitine across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0046466", "l": "membrane lipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010689", "l": "negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus", "d": ["Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a chemical stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060334", "l": "regulation of type II interferon-mediated signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of an interferon-gamma-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900608", "l": "tensidol B biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tensidol B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019886", "l": "antigen processing and presentation of exogenous peptide antigen via MHC class II", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021972", "l": "corticospinal neuron axon guidance through spinal cord", "d": ["The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after decussation through the spinal cord in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035581", "l": "sequestering of extracellular ligand from receptor", "d": ["The process of binding or confining an extracellular signaling ligand, such that the ligand is unable to bind to its cell surface receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071364", "l": "cellular response to epidermal growth factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098596", "l": "imitative learning", "d": ["Learning in which new behaviors are acquired through imitation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097021", "l": "lymphocyte migration into lymphoid organs", "d": ["The movement of a lymphocyte within the lymphatic system into lymphoid organs such as lymph nodes, spleen or Peyer's patches, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.824318789188837", "identifiers": [{"i": "GO:0048588", "l": "developmental cell growth", "d": ["The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000862", "l": "negative regulation of estrogen secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of estrogen secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071293", "l": "cellular response to tellurium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:1902667", "l": "regulation of axon guidance", "d": ["Any process that modulates the frequency, rate or extent of axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0034227", "l": "tRNA thio-modification", "d": ["The addition a sulfur atom to a nucleotide in a tRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060594", "l": "mammary gland specification", "d": ["The regionalization process in which the mammary line is specified. The mammary line is a ridge of epidermal cells that will form the mammary placodes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900128", "l": "regulation of G-protein activated inward rectifier potassium channel activity", "d": ["Any process that modulates the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.35073291073661", "identifiers": [{"i": "GO:0006650", "l": "glycerophospholipid metabolic process", "d": ["The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035207", "l": "negative regulation of hemocyte proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001013", "l": "epithelial cell proliferation involved in renal tubule morphogenesis", "d": ["Any epithelial cell proliferation that is involved in renal tubule morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072209", "l": "metanephric mesangial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the metanephros as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019100", "l": "male germ-line sex determination", "d": ["The determination of sex and sexual phenotype in a male organism's germ line."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990115", "l": "RNA polymerase III assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase III complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014911", "l": "positive regulation of smooth muscle cell migration", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0035434", "l": "copper ion transmembrane transport", "d": ["The directed movement of copper cation across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000671", "l": "regulation of motor neuron apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of motor neuron apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:0043050", "l": "pharyngeal pumping", "d": ["The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002299", "l": "alpha-beta intraepithelial T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of an alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072086", "l": "specification of loop of Henle identity", "d": ["The process in which the loop of Henle of the kidney nephron acquires its identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021644", "l": "vagus nerve morphogenesis", "d": ["The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903943", "l": "regulation of hepatocyte apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0032633", "l": "interleukin-4 production", "d": ["The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061435", "l": "positive regulation of transcription from a mobile element promoter", "d": ["Any process that activates or increases the frequency, rate or extent of transcription from a mobile element promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.033057138195133", "identifiers": [{"i": "GO:2000243", "l": "positive regulation of reproductive process", "d": ["Any process that activates or increases the frequency, rate or extent of reproductive process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0080154", "l": "regulation of fertilization", "d": ["Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903491", "l": "response to simvastatin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a simvastatin stimulus. Simvastatin is a statin used as a cholesterol-lowering and anti-cardiovascular disease drug."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0007447", "l": "imaginal disc pattern formation", "d": ["The regionalization process that results in defined areas of the imaginal disc that will undergo specific cell differentaiton. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000311", "l": "regulation of AMPA receptor activity", "d": ["Any process that modulates the frequency, rate or extent of AMPA selective glutamate receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0018207", "l": "peptidyl-phenylalanine modification", "d": ["The modification of peptidyl-phenylalanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042377", "l": "vitamin K catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018203", "l": "peptidyl-isoleucine modification", "d": ["The modification of peptidyl-isoleucine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000284", "l": "positive regulation of amino acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001572", "l": "lactosylceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018356", "l": "protein-phycobiliviolin linkage via S-phycobiliviolin-L-cysteine", "d": ["The linkage of the chromophore phycobiliviolin to phycoerythrocyanin via S-phycobiliviolin-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140928", "l": "inhibition of non-skeletal tissue mineralization", "d": ["A homeostatic process involved in the maintenance of non-mineral tissue, by preventing mineralization of non-skeletal tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0110122", "l": "myotube cell migration", "d": ["The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905586", "l": "negative regulation of outer hair cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of outer hair cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106122", "l": "negative regulation of cobalamin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a cobalamin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902830", "l": "negative regulation of spinal cord association neuron differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of spinal cord association neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0006560", "l": "proline metabolic process", "d": ["The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0072310", "l": "glomerular epithelial cell development", "d": ["The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072217", "l": "negative regulation of metanephros development", "d": ["Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990626", "l": "mitochondrial outer membrane fusion", "d": ["The membrane organization process that joins two mitochondrial outer membranes to form a single membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060773", "l": "flower phyllotactic patterning", "d": ["The radial pattern formation process that results in the formation of floral organ primordia around a central axis in a flower primordium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0006303", "l": "double-strand break repair via nonhomologous end joining", "d": ["The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904054", "l": "regulation of cholangiocyte proliferation", "d": ["Any process that modulates the frequency, rate or extent of cholangiocyte proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902192", "l": "2-methylbut-2-enoyl-CoA(4-) metabolic process", "d": ["The chemical reactions and pathways involving 2-methylbut-2-enoyl-CoA(4-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019632", "l": "shikimate metabolic process", "d": ["The chemical reactions and pathways involving shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid. It is an important intermediate in the biosynthesis of aromatic amino acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.35073291073661", "identifiers": [{"i": "GO:0002366", "l": "leukocyte activation involved in immune response", "d": ["A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033545", "l": "myo-inositol hexakisphosphate biosynthetic process, lipid-dependent", "d": ["The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002408", "l": "myeloid dendritic cell chemotaxis", "d": ["The movement of a myeloid dendritic cell in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0042743", "l": "hydrogen peroxide metabolic process", "d": ["The chemical reactions and pathways involving hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150136", "l": "regulation of interleukin-37 production", "d": ["Any process that modulates the frequency, rate or extent of interleukin-37 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0006308", "l": "DNA catabolic process", "d": ["The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010214", "l": "seed coat development", "d": ["The process whose specific outcome is the progression of the seed coat over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001966", "l": "thigmotaxis", "d": ["The directed movement of an animal in response to touch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072399", "l": "response to cytokinesis checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of cytokinesis checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902566", "l": "regulation of eosinophil activation", "d": ["Any process that modulates the frequency, rate or extent of eosinophil activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060667", "l": "branch elongation involved in salivary gland morphogenesis", "d": ["The differential growth of the salivary branches along their axis, resulting in the growth of a branch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0030493", "l": "bacteriochlorophyll metabolic process", "d": ["The chemical reactions and pathways involving a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0032196", "l": "transposition", "d": ["Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites. For elements that are transcribed as the first step of transposition, the process starts with the transcription of the transposable element, its translation and maturation, and ending with integration into DNA. For elements that are cut out, the process starts with the excision of the donor DNA and integrated into another site."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002557", "l": "histamine secretion by basophil", "d": ["The regulated release of histamine by a basophil or group of basophils."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0000460", "l": "maturation of 5.8S rRNA", "d": ["Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061027", "l": "umbilical cord development", "d": ["The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904077", "l": "negative regulation of estrogen biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of estrogen biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0006029", "l": "proteoglycan metabolic process", "d": ["The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061449", "l": "olfactory bulb tufted cell development", "d": ["The process whose specific outcome is the progression of an olfactory bulb tufted cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900550", "l": "N',N'',N'''-triacetylfusarinine C catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N',N'',N'''-triacetylfusarinine C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033070", "l": "ansamycin biosynthetic process", "d": ["The chemical reactions and pathways leading to the formation of ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072061", "l": "inner medullary collecting duct development", "d": ["The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900592", "l": "violaceol II catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of violaceol II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990046", "l": "stress-induced mitochondrial fusion", "d": ["Merging of two or more mitochondria within a cell to form a single compartment, as a result of a disturbance in cellular homeostasis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019651", "l": "citrate catabolic process to diacetyl", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of citrate to diacetyl, yielding energy in the form of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051255", "l": "spindle midzone assembly", "d": ["The cell cycle process in which aggregation, arrangement and bonding together of a set of components to form the spindle midzone. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901965", "l": "endoplasmic reticulum to chloroplast transport", "d": ["The directed movement of substances from endoplasmic reticulum to chloroplast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905320", "l": "regulation of mesenchymal stem cell migration", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905219", "l": "regulation of platelet formation", "d": ["Any process that modulates the frequency, rate or extent of platelet formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051308", "l": "male meiosis chromosome separation", "d": ["The process in which paired chromosomes are physically detached from each other during male meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072165", "l": "anterior mesonephric tubule development", "d": ["The progression of the anterior mesonephric tubule over time, from its initial formation to the mature structure. The anterior mesonephric tubule is an epithelial tube that is part of the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046455", "l": "organosilicon catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of organosilicons, any organic compound that contains silicon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060674", "l": "placenta blood vessel development", "d": ["The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140252", "l": "regulation protein catabolic process at postsynapse", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904290", "l": "negative regulation of mitotic DNA damage checkpoint", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic DNA damage checkpoint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080165", "l": "callose deposition in phloem sieve plate", "d": ["Any process in which callose is transported to, and/or maintained in, phloem sieve plate. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045698", "l": "negative regulation of synergid differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of synergid cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019525", "l": "keto-D-gluconate metabolic process", "d": ["The chemical reactions and pathways involving keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0042462", "l": "eye photoreceptor cell development", "d": ["Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904349", "l": "positive regulation of small intestine smooth muscle contraction", "d": ["Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021730", "l": "trigeminal sensory nucleus development", "d": ["The process whose specific outcome is the progression of the trigeminal sensory nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048283", "l": "indeterminate inflorescence morphogenesis", "d": ["The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can produce an undefined number of floral meristems."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904128", "l": "negative regulation of convergent extension involved in somitogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in somitogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046124", "l": "purine deoxyribonucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019743", "l": "hopanoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051884", "l": "regulation of timing of anagen", "d": ["Any process that modulates the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071355", "l": "cellular response to interleukin-9", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010709", "l": "heteroduplex formation involved in double-strand break repair via synthesis-dependent strand annealing", "d": ["The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules resulting in the error-free repair of a double-strand break without the exchange of adjacent sequences."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0010411", "l": "xyloglucan metabolic process", "d": ["The chemical reactions and pathways involving xyloglucan, the cross-linking glycan composed of (1->4)-beta-D-glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071504", "l": "cellular response to heparin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903078", "l": "positive regulation of protein localization to plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031108", "l": "holo-[acyl-carrier-protein] biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of holo-[acyl-carrier protein]."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1900145", "l": "regulation of nodal signaling pathway involved in determination of left/right asymmetry", "d": ["Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000208", "l": "positive regulation of ribosomal small subunit export from nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of ribosomal small subunit export from nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0016144", "l": "S-glycoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034443", "l": "negative regulation of lipoprotein oxidation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein oxidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.362525179576039", "identifiers": [{"i": "GO:0051952", "l": "regulation of amine transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901089", "l": "acetate ester metabolic process involved in fermentation", "d": ["Any acetate ester metabolic process that is involved in fermentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048341", "l": "paraxial mesoderm formation", "d": ["The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0006457", "l": "protein folding", "d": ["The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002734", "l": "negative regulation of myeloid dendritic cell cytokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.261443428098588", "identifiers": [{"i": "GO:0048754", "l": "branching morphogenesis of an epithelial tube", "d": ["The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110027", "l": "negative regulation of DNA strand resection involved in replication fork processing", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA strand resection involved in replication fork processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098824", "l": "peptidyl-cysteine sulfation", "d": ["The sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900454", "l": "positive regulation of long-term synaptic depression", "d": ["Any process that activates or increases the frequency, rate or extent of long term synaptic depression."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071980", "l": "cell surface adhesin-mediated gliding motility", "d": ["Cell gliding that results from the actions of cell surface adhesin proteins that are propelled by membrane motor proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0015723", "l": "bilirubin transport", "d": ["The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0071971", "l": "extracellular exosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070434", "l": "positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002229", "l": "defense response to oomycetes", "d": ["Reactions triggered in response to the presence of oomycetes that act to protect the cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902217", "l": "erythrocyte apoptotic process", "d": ["Any apoptotic process in an erythrocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071327", "l": "cellular response to trehalose stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904087", "l": "negative regulation of epiboly involved in gastrulation with mouth forming second", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015868", "l": "purine ribonucleotide transport", "d": ["The directed movement of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, into, out of or within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048795", "l": "swim bladder morphogenesis", "d": ["The process in which the anatomical structure of the swim bladder is generated and organized. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0032303", "l": "regulation of icosanoid secretion", "d": ["Any process that modulates the frequency, rate or extent of the controlled release of an icosanoid from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0043524", "l": "negative regulation of neuron apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033050", "l": "clavulanic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010908", "l": "regulation of heparan sulfate proteoglycan biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010187", "l": "negative regulation of seed germination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of seed germination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903823", "l": "telomere single strand break repair", "d": ["Single strand break repair that takes place in a telomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035703", "l": "monocyte migration into blood stream", "d": ["The movement of a monocyte from the bone marrow to the blood stream."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032295", "l": "ensheathment of neuronal cell bodies", "d": ["The process in which satellite glial cells isolate neuronal cell bodies."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032793", "l": "positive regulation of CREB transcription factor activity", "d": ["Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900035", "l": "negative regulation of cellular response to heat", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to heat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010964", "l": "regulation of regulatory ncRNA-mediated heterochromatin formation", "d": ["Any process that modulates the frequency, rate or extent of small non-coding RNA-mediated heterochromatin formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902258", "l": "positive regulation of apoptotic process involved in outflow tract morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903978", "l": "regulation of microglial cell activation", "d": ["Any process that modulates the frequency, rate or extent of microglial cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032763", "l": "regulation of mast cell cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of mast cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1900864", "l": "mitochondrial RNA modification", "d": ["Any RNA modification that takes place in mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902726", "l": "positive regulation of skeletal muscle satellite cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of satellite cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090084", "l": "negative regulation of inclusion body assembly", "d": ["Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901944", "l": "miltiradiene metabolic process", "d": ["The chemical reactions and pathways involving miltiradiene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0042168", "l": "heme metabolic process", "d": ["The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048023", "l": "positive regulation of melanin biosynthetic process", "d": ["Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:0042311", "l": "vasodilation", "d": ["An increase in the internal diameter of blood vessels, especially arterioles or capillaries, due to relaxation of smooth muscle cells that line the vessels, and usually resulting in a decrease in blood pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0070252", "l": "actin-mediated cell contraction", "d": ["The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902642", "l": "negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010417", "l": "glucuronoxylan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucuronoxylan, a polymer containing a beta-1,4-linked D-xylose backbone substituted with glucuronic acid residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150045", "l": "regulation of synaptic signaling by nitric oxide", "d": ["Any process that modulates the frequency, rate or extent of synaptic signaling by nitric oxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904199", "l": "positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization", "d": ["Any process that activates or increases the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0071706", "l": "tumor necrosis factor superfamily cytokine production", "d": ["The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035171", "l": "lamellocyte differentiation", "d": ["The process in which a relatively unspecialized hemocyte precursor cell acquires the specialized features of a lamellocyte. Lamellocytes are a hemocyte lineage that exists only in larvae, but are seldom observed in healthy animals. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902629", "l": "regulation of mRNA stability involved in cellular response to UV", "d": ["Any regulation of mRNA stability that is involved in cellular response to UV."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0044558", "l": "uterine smooth muscle relaxation", "d": ["A process in which the extent of smooth muscle contraction is reduced in the uterus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900114", "l": "positive regulation of histone H3-K9 trimethylation", "d": ["Any process that activates or increases the frequency, rate or extent of histone H3-K9 trimethylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072004", "l": "kidney field specification", "d": ["The process that results in the delineation of regions of the embryo into the area in which the kidney rudiment will develop."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042042", "l": "tungsten incorporation into tungsten-molybdopterin complex", "d": ["The incorporation of tungsten into a tungsten-molybdopterin complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018164", "l": "protein-DNA covalent cross-linking via peptidyl-threonine", "d": ["The formation of a covalent cross-link between DNA and a peptidyl-threonine residue by the formation of O-(phospho-5'-DNA)-L-threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0018871", "l": "1-aminocyclopropane-1-carboxylate metabolic process", "d": ["The chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032718", "l": "negative regulation of interleukin-9 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-9 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015895", "l": "alkane transport", "d": ["The directed movement of alkanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanes are saturated aliphatic hydrocarbon compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.744066580938323", "identifiers": [{"i": "GO:0072088", "l": "nephron epithelium morphogenesis", "d": ["The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061173", "l": "positive regulation of establishment of bipolar cell polarity", "d": ["Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000732", "l": "positive regulation of termination of RNA polymerase I transcription", "d": ["Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase I transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0052043", "l": "modification by symbiont of host cellular component", "d": ["The process in which an organism effects a change in the structure or function of a host cellular component. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001247", "l": "positive regulation of phosphatidylcholine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990268", "l": "response to gold nanoparticle", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold nanoparticle stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021716", "l": "inferior olivary nucleus structural organization", "d": ["The process that contributes to the act of creating the structural organization of the inferior olivary nucleus structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.585103934178449", "identifiers": [{"i": "GO:0008645", "l": "hexose transmembrane transport", "d": ["The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0010972", "l": "negative regulation of G2/M transition of mitotic cell cycle", "d": ["Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900634", "l": "pentadecane biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pentadecane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099009", "l": "viral genome circularization", "d": ["The circularization of a viral genome following infection of a host cell. This is common amongst bacterial viruses to protect the viral genome ends from nucleases, to convert the linear genome to an integrative precursor or to give rise to the replicative form of the genome. It can be mediated by covalent closure of the DNA sticky ends, recombinaison between redundant terminal sequences or via the binding of a protein at the viral DNA extremities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030590", "l": "first cell cycle pseudocleavage", "d": ["A process that occurs during the first cell cycle in an embryo, in which anterior cortical contractions culminate in a single partial constriction of the embryo called the pseudocleavage furrow. An example of this process is found in nematode worms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036416", "l": "tRNA stabilization", "d": ["Prevention of degradation of tRNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070157", "l": "mitochondrial prolyl-tRNA aminoacylation", "d": ["The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003138", "l": "primary heart field specification", "d": ["The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0019740", "l": "nitrogen utilization", "d": ["A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary nitrogen source, usually ammonia, and then activates genes to scavenge the last traces of the primary nitrogen source and to transport and metabolize alternative nitrogen sources. The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, and ends when nitrogen is incorporated into the cell or organism's metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0007080", "l": "mitotic metaphase plate congression", "d": ["The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the mitotic spindle, during mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010694", "l": "positive regulation of alkaline phosphatase activity", "d": ["Any process that increases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009947", "l": "centrolateral axis specification", "d": ["The establishment, maintenance and elaboration of the centrolateral axis. In plants, this axis is duplicated and runs from the midrib to the margin of the leaf."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014728", "l": "regulation of the force of skeletal muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of the force of skeletal muscle contraction. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through the formation of cross bridges."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000713", "l": "negative regulation of maintenance of meiotic sister chromatid cohesion, arms", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070144", "l": "mitochondrial arginyl-tRNA aminoacylation", "d": ["The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0039693", "l": "viral DNA genome replication", "d": ["The replication of a viral DNA genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001238", "l": "positive regulation of extrinsic apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0097278", "l": "complement-dependent cytotoxicity", "d": ["Cell killing caused by the membrane attack complex formed following complement activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903954", "l": "positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization", "d": ["Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090009", "l": "primitive streak formation", "d": ["The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0001914", "l": "regulation of T cell mediated cytotoxicity", "d": ["Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035433", "l": "acetate transmembrane transport", "d": ["The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048301", "l": "positive regulation of isotype switching to IgD isotypes", "d": ["Any process that activates or increases the frequency, rate or extent of isotype switching to IgD isotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016555", "l": "uridine to cytidine editing", "d": ["The conversion of a uridine residue to cytosine in an RNA molecule by amination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019096", "l": "pole plasm mitochondrial lrRNA localization", "d": ["Any process in which mitochondrial large ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000923", "l": "positive regulation of arabinoxylan-containing compound catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of arabinoxylan-containing compound catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042853", "l": "L-alanine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009188", "l": "ribonucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:1903053", "l": "regulation of extracellular matrix organization", "d": ["Any process that modulates the frequency, rate or extent of extracellular matrix organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010379", "l": "phaseic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phaseic acid (PA), a catabolite of the plant hormone abscisic acid (ABA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002420", "l": "natural killer cell mediated cytotoxicity directed against tumor cell target", "d": ["The directed killing of a tumor cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035430", "l": "regulation of gluconate transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a gluconate across a membrane by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000709", "l": "regulation of maintenance of meiotic sister chromatid cohesion, centromeric", "d": ["Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.780178523879258", "identifiers": [{"i": "GO:0002521", "l": "leukocyte differentiation", "d": ["The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017181", "l": "peptidyl-diphthine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of peptidyl-diphthine, a modified histidine residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0014889", "l": "muscle atrophy", "d": ["A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903639", "l": "regulation of gastrin-induced gastric acid secretion", "d": ["Any process that modulates the frequency, rate or extent of gastrin-induced gastric acid secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0006892", "l": "post-Golgi vesicle-mediated transport", "d": ["The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000949", "l": "aromatic amino acid family catabolic process to alcohol via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of aromatic amino acids to produce aromatic alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanol, 4-hydroxyphenylethanol, or tryptophol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904603", "l": "regulation of advanced glycation end-product receptor activity", "d": ["Any process that modulates the frequency, rate or extent of advanced glycation end-product receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006014", "l": "D-ribose metabolic process", "d": ["The chemical reactions and pathways involving D-ribose (ribo-pentose). As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0014072", "l": "response to isoquinoline alkaloid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.362525179576039", "identifiers": [{"i": "GO:0048512", "l": "circadian behavior", "d": ["The specific behavior of an organism that recurs with a regularity of approximately 24 hours."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0106027", "l": "neuron projection organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904011", "l": "cellular response to Aroclor 1254", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075201", "l": "penetration hypha formation", "d": ["The assembly by the symbiont of a threadlike, tubular structure, which may contain multiple nuclei and may or may not be divided internally by septa or cross-walls, for the purpose of penetration into its host organism. In the case of an appressorium existing, this term is defined in further details as the process in which the symbiont penetration peg expands to form a hypha which traverses the epidermal cell and emerges into the intercellular space of the mesophyll tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0007598", "l": "blood coagulation, extrinsic pathway", "d": ["A protein activation cascade that contributes to blood coagulation and consists of the self-limited process linking exposure and activation of tissue factor to the activation of clotting factor X."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010239", "l": "chloroplast mRNA processing", "d": ["Steps involved in processing precursor RNAs arising from transcription of operons in the chloroplast genome into mature mRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021629", "l": "olfactory nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033511", "l": "luteolin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0055015", "l": "ventricular cardiac muscle cell development", "d": ["The process whose specific outcome is the progression of a ventricular cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990646", "l": "cellular response to prolactin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902939", "l": "negative regulation of intracellular calcium activated chloride channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intracellular calcium activated chloride channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000956", "l": "positive regulation of cyclodextrin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cyclodextrin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071717", "l": "thromboxane transport", "d": ["The directed movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900700", "l": "positive regulation of o-orsellinic acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of o-orsellinic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007305", "l": "vitelline membrane formation involved in chorion-containing eggshell formation", "d": ["Construction of the vitelline membrane portion of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035759", "l": "mesangial cell-matrix adhesion", "d": ["The binding of a mesangial cell to the extracellular matrix via adhesion molecules. A mesangial cell is a cell that encapsulates the capillaries and venules in the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0034090", "l": "maintenance of meiotic sister chromatid cohesion", "d": ["The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0003401", "l": "axis elongation", "d": ["The developmental growth that results in the elongation of a line that defines polarity or symmetry in an anatomical structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000468", "l": "generation of mature 3'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Any process involved in generating the mature 3'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098825", "l": "peptidyl-histidine guanylation", "d": ["The guanylylation of peptidyl-histidine to form (phospho-5'-guanosine)-L-histidine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0017014", "l": "protein nitrosylation", "d": ["The covalent addition of a nitric oxide group to an amino acid within a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0051306", "l": "mitotic sister chromatid separation", "d": ["The process in which sister chromatids are physically detached from each other during mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098819", "l": "depolarization of postsynaptic membrane", "d": ["A process that depolarizes a postsynaptic membrane relative to its resting potential. This has an excitatory effect on the post-synaptic cell, moving the membrane potential towards the firing threshold."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032516", "l": "positive regulation of phosphoprotein phosphatase activity", "d": ["Any process that activates or increases the activity of a phosphoprotein phosphatase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000133", "l": "positive regulation of tyramine signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of tyramine signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990058", "l": "fruit replum development", "d": ["The process whose specific outcome is the progression of the fruit replum over time, from its formation to the mature structure. The fruit replum is a portion of fruit placenta tissue that divides a fruit into two or more chambers and develops from a replum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.248384282929521", "identifiers": [{"i": "GO:1901616", "l": "organic hydroxy compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061431", "l": "cellular response to methionine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900149", "l": "positive regulation of Schwann cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of Schwann cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001296", "l": "N(omega)-methyl-L-arginine metabolic process", "d": ["The chemical reactions and pathways involving N(omega)-methyl-L-arginine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009600", "l": "detection of nematode", "d": ["The series of events in which a stimulus from a nematode is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061591", "l": "calcium activated galactosylceramide scrambling", "d": ["The movement of a population of galactosylceramide molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0005990", "l": "lactose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lactose, the disaccharide galactopyranosyl-glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043617", "l": "cellular response to sucrose starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sucrose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:1902930", "l": "regulation of alcohol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of alcohol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006543", "l": "glutamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamine, 2-amino-4-carbamoylbutanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010771", "l": "negative regulation of cell morphogenesis involved in differentiation", "d": ["Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history."]}]}
{"type": "biolink:BiologicalProcess", "ic": "48.648354917483516", "identifiers": [{"i": "GO:0007269", "l": "neurotransmitter secretion", "d": ["The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006432", "l": "phenylalanyl-tRNA aminoacylation", "d": ["The process of coupling phenylalanine to phenylalanyl-tRNA, catalyzed by phenylalanyl-tRNA synthetase. The phenylalanyl-tRNA synthetase is a class-II synthetase. However, unlike other class II enzymes, The activated amino acid is transferred to the 2'-OH group of a phenylalanine-accepting tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1990758", "l": "mitotic sister chromatid biorientation", "d": ["The mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed. This is the final step in metaphase plate congression."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.661622235043069", "identifiers": [{"i": "GO:0016051", "l": "carbohydrate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051661", "l": "maintenance of centrosome location", "d": ["Any process in which a centrosome is maintained in a specific location within a cell and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0048653", "l": "anther development", "d": ["The process whose specific outcome is the progression of the anther over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060177", "l": "regulation of angiotensin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving angiotensin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1905898", "l": "positive regulation of response to endoplasmic reticulum stress", "d": ["Any process that activates or increases the frequency, rate or extent of response to endoplasmic reticulum stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051343", "l": "positive regulation of cyclic-nucleotide phosphodiesterase activity", "d": ["Any process that activates or increases the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0048489", "l": "synaptic vesicle transport", "d": ["The directed movement of synaptic vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.523519163150823", "identifiers": [{"i": "GO:0031344", "l": "regulation of cell projection organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0006080", "l": "substituted mannan metabolic process", "d": ["The chemical reactions and pathways involving a mannan backbone composed of D-mannose unites, substituted with D-glucose and/or D-galactose units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021956", "l": "central nervous system interneuron axonogenesis", "d": ["Generation of a long process that carries efferent (outgoing) action potentials from the cell body towards target cells from a neuron located in the central nervous system whose axons remain within a single brain region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036261", "l": "7-methylguanosine cap hypermethylation", "d": ["Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "44.800698612194324", "identifiers": [{"i": "GO:0006811", "l": "monoatomic ion transport", "d": ["The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.170973648324292", "identifiers": [{"i": "GO:0030155", "l": "regulation of cell adhesion", "d": ["Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901196", "l": "positive regulation of calcium-mediated signaling involved in cellular response to salt stress", "d": ["Any positive regulation of calcium-mediated signaling that is involved in cellular response to salt stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904681", "l": "response to 3-methylcholanthrene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903775", "l": "regulation of DNA double-strand break processing", "d": ["Any process that modulates the frequency, rate or extent of DNA double-strand break processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006654", "l": "phosphatidic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0046490", "l": "isopentenyl diphosphate metabolic process", "d": ["The chemical reactions and pathways involving isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0030584", "l": "sporocarp development", "d": ["The process whose specific outcome is the progression of a sporocarp over time, from its formation to the mature structure. The sporocarp is a spore bearing fruiting body organ. An example of this process is found in the Fungal species Coprinopsis cinerea."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903653", "l": "modulation by symbiont of host cell motility", "d": ["Modulation of host cell motility by a symbiont of that host."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032693", "l": "negative regulation of interleukin-10 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071448", "l": "cellular response to alkyl hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0010054", "l": "trichoblast differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a trichoblast, a root epidermal cell that will give rise to a root hair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071484", "l": "cellular response to light intensity", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140145", "l": "copper ion export from vacuole", "d": ["The directed movement of copper ions out of the vacuole across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051999", "l": "mannosyl-inositol phosphorylceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071668", "l": "plant-type cell wall assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a cellulose- and pectin-containing cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0016344", "l": "meiotic chromosome movement towards spindle pole", "d": ["The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles takes place, mediated by the shortening of microtubules attached to the chromosomes. This occurs during meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045162", "l": "clustering of voltage-gated sodium channels", "d": ["The process in which voltage-gated sodium channels become localized together in high densities. In animals, nodes of Ranvier differ dramatically from internodal axonal regions in very high densities of voltage-dependent sodium (Nav) channels responsible for the rapid, inward ionic currents that produce membrane depolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006127", "l": "glycerophosphate shuttle", "d": ["The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002931", "l": "response to ischemia", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904554", "l": "positive regulation of chemotaxis to arachidonic acid", "d": ["Any process that activates or increases the frequency, rate or extent of chemotaxis to arachidonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0014909", "l": "smooth muscle cell migration", "d": ["The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1904306", "l": "positive regulation of gastro-intestinal system smooth muscle contraction", "d": ["Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.659246641645865", "identifiers": [{"i": "GO:0042113", "l": "B cell activation", "d": ["The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021948", "l": "inward migration of deep nuclear neurons", "d": ["The directed movement of a deep nuclear neuron from the rostrodorsal region of the cerebellar plate to their final more ventral position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021669", "l": "rhombomere 6 formation", "d": ["The process that gives rise to rhombomere 6. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010263", "l": "tricyclic triterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tricyclic triterpenoid compounds, terpenoids with 6 isoprene units and 3 carbon rings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.958948251787156", "identifiers": [{"i": "GO:0032989", "l": "cellular component morphogenesis", "d": ["The process in which cellular structures, including whole cells or cell parts, are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.332994615078228", "identifiers": [{"i": "GO:0006351", "l": "DNA-templated transcription", "d": ["The synthesis of an RNA transcript from a DNA template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006419", "l": "alanyl-tRNA aminoacylation", "d": ["The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a class-II synthetases. The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034152", "l": "negative regulation of toll-like receptor 6 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 6 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:1903725", "l": "regulation of phospholipid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of phospholipid metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990737", "l": "response to manganese-induced endoplasmic reticulum stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of endoplasmic reticulum stress caused by a manganese stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0060251", "l": "regulation of glial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of glial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030889", "l": "negative regulation of B cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of B cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060256", "l": "regulation of flocculation", "d": ["Any process that modulates the rate, frequency or extent of the non-sexual aggregation of single-celled organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000247", "l": "positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape", "d": ["Any process that activates or increases the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006499", "l": "N-terminal protein myristoylation", "d": ["The covalent attachment of a myristoyl group to the N-terminal amino acid residue of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0006451", "l": "translational readthrough", "d": ["The continuation of translation beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0003383", "l": "apical constriction", "d": ["The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902923", "l": "poly(3-hydroxyvalerate) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(3-hydroxyvalerate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044516", "l": "positive regulation of glucagon-like peptide receptor 1 activity in another organism", "d": ["A process that activates or increases the frequency, rate or extent of the activity of a glucagon-like peptide receptor 1 in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0072091", "l": "regulation of stem cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010423", "l": "negative regulation of brassinosteroid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901726", "l": "negative regulation of histone deacetylase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of histone deacetylase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071284", "l": "cellular response to lead ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0001325", "l": "formation of extrachromosomal circular DNA", "d": ["Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033323", "l": "choline biosynthetic process via CDP-choline", "d": ["The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate CDP-choline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.062476272212777", "identifiers": [{"i": "GO:0002335", "l": "mature B cell differentiation", "d": ["The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060400", "l": "negative regulation of growth hormone receptor signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0030223", "l": "neutrophil differentiation", "d": ["The process in which a myeloid precursor cell acquires the specialized features of a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030589", "l": "pseudocleavage involved in syncytial blastoderm formation", "d": ["Formation of furrows in the cytoplasm between nuclei during cell cycles in embryos that contribute to the formation of the syncytial blastoderm. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021691", "l": "cerebellar Purkinje cell layer maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007512", "l": "adult heart development", "d": ["The process whose specific outcome is the progression of the adult heart over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036047", "l": "peptidyl-lysine demalonylation", "d": ["The process of removing a malonyl group (CO-CH2-CO) from an malonylated lysine residue in a peptide or protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002564", "l": "alternate splicing of immunoglobulin genes", "d": ["The generation of alternate transcripts of immunoglobulin genes through alternate splicing of exons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904508", "l": "regulation of protein localization to basolateral plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of protein localization to basolateral plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033292", "l": "T-tubule organization", "d": ["A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007089", "l": "traversing start control point of mitotic cell cycle", "d": ["A cell cycle process by which a cell commits to entering S phase via a positive feedback mechanism between the regulation of transcription and G1 CDK activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070946", "l": "neutrophil-mediated killing of gram-positive bacterium", "d": ["The directed killing of a gram-positive bacterium by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001196", "l": "positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine", "d": ["Any process that activates or increases the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043503", "l": "skeletal muscle fiber adaptation", "d": ["Any process in which the skeletal muscle fibers change their phenotypic profiles in response to altered functional demands and a variety of signals. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0007098", "l": "centrosome cycle", "d": ["The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030706", "l": "germarium-derived oocyte differentiation", "d": ["The process in which one relatively unspecialized immature cystocyte of the germ-line cyst in the germarium acquires the specialized features of an oocyte. An example of this process can be found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0080152", "l": "regulation of reductive pentose-phosphate cycle", "d": ["Any process that modulates the frequency, rate or extent of reductive pentose-phosphate cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0042119", "l": "neutrophil activation", "d": ["The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097705", "l": "vascular endothelial cell response to pulsatile fluid shear stress", "d": ["Any response to pulsatile fluid shear stress that occurs in a vascular endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048282", "l": "determinate inflorescence morphogenesis", "d": ["The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can only produce a predetermined number of floral meristems."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035159", "l": "regulation of tube length, open tracheal system", "d": ["Ensuring that a tube in an open tracheal system is of the correct length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904895", "l": "ESCRT complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an ESCRT complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032510", "l": "endosome to lysosome transport via multivesicular body sorting pathway", "d": ["The directed movement of substances from endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014882", "l": "regulation of myofibril number", "d": ["Any process that modulates the number of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048807", "l": "female genitalia morphogenesis", "d": ["The process in which the anatomical structures of female genitalia are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051680", "l": "6-alpha-maltosylglucose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 6-alpha-maltosylglucose, also known as isopanose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060543", "l": "negative regulation of strand invasion", "d": ["Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2001054", "l": "negative regulation of mesenchymal cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0046854", "l": "phosphatidylinositol phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidylinositol phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035498", "l": "carnosine metabolic process", "d": ["The chemical reactions and pathways involving the dipeptide beta-alanyl-L-histidine (carnosine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010641", "l": "positive regulation of platelet-derived growth factor receptor signaling pathway", "d": ["Any process that increases the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061428", "l": "negative regulation of transcription from RNA polymerase II promoter in response to hypoxia", "d": ["Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900703", "l": "positive regulation of orcinol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of orcinol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061619", "l": "glycolytic process from mannose through fructose-6-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of mannose into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.186672236700218", "identifiers": [{"i": "GO:0043933", "l": "protein-containing complex organization", "d": ["Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1904981", "l": "maltose transmembrane transport", "d": ["The process in which maltose is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021607", "l": "accessory nerve morphogenesis", "d": ["The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018961", "l": "pentachlorophenol metabolic process", "d": ["The chemical reactions and pathways involving pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901036", "l": "positive regulation of L-glutamine import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of L-glutamine import into cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0043936", "l": "asexual sporulation resulting in formation of a cellular spore", "d": ["The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071205", "l": "protein localization to juxtaparanode region of axon", "d": ["Any process in which a protein is transported to, or maintained at, the juxtaparanode region of an axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010798", "l": "regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism", "d": ["Any process that modulates the volume of a multivesicular body as part of the chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.572744119402742", "identifiers": [{"i": "GO:0006493", "l": "protein O-linked glycosylation", "d": ["A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0099514", "l": "synaptic vesicle cytoskeletal transport", "d": ["The directed movement of synaptic vesicles along cytoskeletal fibers such as microfilaments or microtubules within a cell, powered by molecular motors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002565", "l": "somatic diversification of immune receptors via gene conversion", "d": ["The process in which immune receptor genes are diversified through gene conversion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070956", "l": "negative regulation of neutrophil mediated killing of bacterium", "d": ["Any process that decreases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0036503", "l": "ERAD pathway", "d": ["The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010601", "l": "positive regulation of auxin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002023", "l": "reduction of food intake in response to dietary excess", "d": ["An eating behavior process whereby detection of a dietary excess results in a decrease in intake of nutrients."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0042471", "l": "ear morphogenesis", "d": ["The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002122", "l": "fear-induced aggressive behavior", "d": ["Aggressive behavior associated with attempts to flee from a threat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046825", "l": "regulation of protein export from nucleus", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038175", "l": "negative regulation of SREBP signaling pathway in response to increased oxygen levels", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway in response to an increase in oxygen levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000395", "l": "mRNA 5'-splice site recognition", "d": ["Recognition of the intron 5'-splice site by components of the assembling spliceosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010192", "l": "mucilage biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mucilage, a gelatinous substance secreted by plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072653", "l": "interferon-omega production", "d": ["The appearance of interferon-omega due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043116", "l": "negative regulation of vascular permeability", "d": ["Any process that reduces the extent to which blood vessels can be pervaded by fluid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0031281", "l": "positive regulation of cyclase activity", "d": ["Any process that activates or increases the activity of a cyclase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0060618", "l": "nipple development", "d": ["The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0009847", "l": "spore germination", "d": ["The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039688", "l": "viral double stranded DNA replication via reverse transcription", "d": ["A DNA replication process that uses viral RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0072596", "l": "establishment of protein localization to chloroplast", "d": ["The directed movement of a protein to a specific location in a chloroplast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0007084", "l": "mitotic nuclear membrane reassembly", "d": ["The mitotic cell cycle process involving ESCRTIII that results in reformation of the nuclear envelope after mitotic nuclear division. In organisms undergoing closed mitosis this involves resealing or 'repair' of the nuclear envelope in the nuclear bridge."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0070295", "l": "renal water absorption", "d": ["A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905706", "l": "regulation of mitochondrial ATP synthesis coupled proton transport", "d": ["Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0032418", "l": "lysosome localization", "d": ["Any process in which a lysosome is transported to, and/or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903124", "l": "negative regulation of thioredoxin peroxidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of thioredoxin peroxidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900839", "l": "positive regulation of fumigaclavine C biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of fumigaclavine C biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901922", "l": "regulation of sclerotium development", "d": ["Any process that modulates the frequency, rate or extent of sclerotium development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035864", "l": "response to potassium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061757", "l": "leukocyte adhesion to arterial endothelial cell", "d": ["The attachment of a leukocyte to an arterial endothelial cell via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1900426", "l": "positive regulation of defense response to bacterium", "d": ["Any process that activates or increases the frequency, rate or extent of defense response to bacterium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1905071", "l": "tight junction disassembly", "d": ["The disaggregation of an tight junction into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0003241", "l": "growth involved in heart morphogenesis", "d": ["Developmental growth that contributes to the shaping of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0050891", "l": "multicellular organismal-level water homeostasis", "d": ["A chemical homeostatic process involved in the maintenance of a steady state level of water within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048172", "l": "regulation of short-term neuronal synaptic plasticity", "d": ["A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010440", "l": "stomatal lineage progression", "d": ["The process in which an unspecialized epidermal cell progresses through a series of divisions that culminate in the production of a stomatal complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061110", "l": "dense core granule biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a dense core granule. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the dense core granule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036275", "l": "response to 5-fluorouracil", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluorouracil stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071390", "l": "cellular response to ecdysone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072489", "l": "methylammonium transmembrane transport", "d": ["The process in which methylammonium is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061254", "l": "mesonephric glomerular parietal epithelial cell development", "d": ["The process whose specific outcome is the progression of a mesonephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002493", "l": "lipid antigen assembly with MHC class Ib protein complex", "d": ["The binding of a lipid antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 gene family."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010481", "l": "epidermal cell division", "d": ["Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019856", "l": "pyrimidine nucleobase biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902104", "l": "positive regulation of metaphase/anaphase transition of meiotic cell cycle", "d": ["Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "46.80276342006254", "identifiers": [{"i": "GO:0042221", "l": "response to chemical", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036022", "l": "limb joint morphogenesis", "d": ["The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098909", "l": "regulation of cardiac muscle cell action potential involved in regulation of contraction", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell contributing to the regulation of its contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045873", "l": "negative regulation of sevenless signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the sevenless signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051633", "l": "positive regulation of acetylcholine uptake", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033585", "l": "L-phenylalanine biosynthetic process from chorismate via phenylpyruvate", "d": ["The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate phenylpyruvate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902492", "l": "positive regulation of sperm capacitation", "d": ["Any process that activates or increases the frequency, rate or extent of sperm capacitation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051823", "l": "regulation of synapse structural plasticity", "d": ["Any process that modulates the frequency, rate or extent of synapse structural plasticity. Synapse structural plasticity is a type of cytoskeletal remodeling; this remodeling is induced by stimuli that can lead to long term potentiation and it can be activity-dependent or -independent. Examples of cytoskeletal changes include the formation of new spines and increase in spine size; this can be accompanied by the insertion of greater numbers of glutamate (or other neurotransmitter) receptors into the post-synaptic membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045804", "l": "negative regulation of eclosion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046052", "l": "UTP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of UTP, uridine (5'-)triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901943", "l": "(+)-epi-alpha-bisabolol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (+)-epi-alpha-bisabolol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009558", "l": "embryo sac cellularization", "d": ["The process in which the eight-nucleate single celled female gametophyte develops into the seven-celled female gametophyte. This mature structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. An example of this process is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001118", "l": "transcription ternary complex disassembly", "d": ["The disaggregation of a transcription ternary complex, composed of RNA polymerase, template DNA, and an RNA transcript, into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043972", "l": "histone H3-K23 acetylation", "d": ["The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 23 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140668", "l": "positive regulation of oxytocin production", "d": ["Any process that activates or increases the frequency, rate or extent of production of oxytocin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0005982", "l": "starch metabolic process", "d": ["The chemical reactions and pathways involving starch, the most important reserve polysaccharide in plants. It is a glucan consisting of two components, amylose and amylopectin, which are both glucose homopolymers. Starch is synthesized as a temporary storage form of carbon and can be catabolized to produce sucrose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010794", "l": "regulation of dolichol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of dolichol biosynthesis. Dolichol biosynthesis consists of the chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.085121200529862", "identifiers": [{"i": "GO:0070588", "l": "calcium ion transmembrane transport", "d": ["A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905168", "l": "positive regulation of double-strand break repair via homologous recombination", "d": ["Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0030510", "l": "regulation of BMP signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902852", "l": "regulation of nuclear migration during mitotic telophase", "d": ["Any process that modulates the frequency, rate or extent of nuclear migration during mitotic telophase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019398", "l": "gallate catabolic process via gallate dioxygenase activity", "d": ["The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, where the first step is the conversion of gallate to (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate catalyzed by gallate dioxygenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0042357", "l": "thiamine diphosphate metabolic process", "d": ["The chemical reactions and pathways involving thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904428", "l": "negative regulation of tubulin deacetylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900656", "l": "negative regulation of diorcinol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of diorcinol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902484", "l": "Sertoli cell apoptotic process", "d": ["Any apoptotic process in a Sertoli cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000783", "l": "negative regulation of establishment of cell polarity regulating cell shape", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of cell polarity regulating cell shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030399", "l": "autophagosome membrane disassembly", "d": ["The controlled breakdown of the membranes of autophagosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0075215", "l": "modulation of spore encystment on host", "d": ["Any process that modulates the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033395", "l": "beta-alanine biosynthetic process via 3-hydroxypropionate", "d": ["The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-hydroxypropionate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0075118", "l": "modulation by symbiont of host G protein-coupled receptor signal transduction", "d": ["Any process in which the symbiont modulates the frequency, rate or extent of the host G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905479", "l": "negative regulation of glutamate-ammonia ligase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glutamate-ammonia ligase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0051523", "l": "cell growth mode switching, monopolar to bipolar", "d": ["The process in which a cell switches from monopolar cell growth to bipolar cell growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001880", "l": "Mullerian duct regression", "d": ["The process in which the Mullerian ducts, primordia of the oviducts, uterus and upper vagina, undergo regression in male embryos."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900330", "l": "regulation of methane biosynthetic process from trimethylamine", "d": ["Any process that modulates the frequency, rate or extent of methane biosynthetic process from trimethylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990910", "l": "response to hypobaric hypoxia", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension combined with low atmospheric pressure. Hypoxia is defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95% and hypobaric is defined as atmospheric pressure below 0.74 atm (greater than 2,500 m above sea level)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.254170199969643", "identifiers": [{"i": "GO:0006753", "l": "nucleoside phosphate metabolic process", "d": ["The chemical reactions and pathways involving any phosphorylated nucleoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:1903317", "l": "regulation of protein maturation", "d": ["Any process that modulates the frequency, rate or extent of protein maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905805", "l": "excitatory synapse pruning", "d": ["The disaggregation of an excitatory synapse into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0048675", "l": "axon extension", "d": ["Long distance growth of a single axon process involved in cellular development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060736", "l": "prostate gland growth", "d": ["The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075112", "l": "modulation by symbiont of host transmembrane receptor-mediated signal transduction", "d": ["Any process in which the symbiont modulates the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0140766", "l": "siRNA-mediated gene silencing", "d": ["A post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) elicit silencing of specific target genes. siRNAs are 21-23 nucleotide RNA duplexes that are fully complementary to their target mRNA. siRNAs can be exported and act in other cells, including in germline cells. Once incorporated into a RNA-induced silencing complex (RISC), siRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endonucleolytic cleavage of the mRNA or mRNA translational repression. siRNAs are present in lower animals and plants, but not found in mammals; whereas miRNAs are present in all the animals and in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002542", "l": "Factor XII activation", "d": ["Any process that activates Factor XII (Hageman factor). Factor XII is a protein synthesized by the liver that circulates in an inactive form until it encounters collagen or basement membrane or activated platelets (as occurs at the site of endothelial injury). Factor XII then undergoes a conformational change (becoming factor XIIa), exposing an active serine center that can subsequently cleave protein substrates and activate a variety of mediator systems. Factor XII is a participant in the clotting cascade as well as the kinin cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.899691898366321", "identifiers": [{"i": "GO:0043414", "l": "macromolecule methylation", "d": ["The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120196", "l": "negative regulation of anther dehiscence", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of anther dehiscence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0106049", "l": "regulation of cellular response to osmotic stress", "d": ["Any process that modulates the frequency, rate or extent of the cellular response to osmotic stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045176", "l": "apical protein localization", "d": ["Any process in which a protein is transported to, or maintained in, apical regions of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085034", "l": "disruption of host I-kappaB kinase/NF-kappaB cascade", "d": ["Any process that interferes with host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032849", "l": "positive regulation of cellular pH reduction", "d": ["Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019486", "l": "beta-alanine catabolic process to mevalonate semialdehyde, by transamination", "d": ["The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including mevalonate semialdehyde, by transamination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.332154193662163", "identifiers": [{"i": "GO:0060284", "l": "regulation of cell development", "d": ["Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002235", "l": "detection of unfolded protein", "d": ["The series of events in which an unfolded protein stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098761", "l": "cellular response to interleukin-7", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0019070", "l": "viral genome maturation", "d": ["The processes involved in creating a mature, stable viral genome. Begins after genome replication with a newly synthesized nucleic acid and ends when the genome is ready to be packaged. Includes the addition of proteins to the newly synthesized genome, and DNA repair processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0003128", "l": "heart field specification", "d": ["The process that results in the delineation of a specific region of the lateral mesoderm into the area in which the heart will develop."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000182", "l": "regulation of progesterone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of progesterone biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061906", "l": "autophagosome localization", "d": ["Any process in which an autophagosome is transported to, and/or maintained in, a specific location within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0061082", "l": "myeloid leukocyte cytokine production", "d": ["Any process that contributes to cytokine production by a myeloid cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0010822", "l": "positive regulation of mitochondrion organization", "d": ["Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.115164699299683", "identifiers": [{"i": "GO:0045448", "l": "mitotic cell cycle, embryonic", "d": ["The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0019184", "l": "nonribosomal peptide biosynthetic process", "d": ["The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048374", "l": "regulation of lateral mesodermal cell fate determination", "d": ["Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0090306", "l": "meiotic spindle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001230", "l": "positive regulation of response to gamma radiation", "d": ["Any process that activates or increases the frequency, rate or extent of response to gamma radiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099159", "l": "regulation of modification of postsynaptic structure", "d": ["Any process that modulates the frequency, rate or extent of modification of postsynaptic structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905242", "l": "response to 3,3',5-triiodo-L-thyronine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051476", "l": "phosphoenolpyruvate-dependent mannosylglycerate phosphotransferase system", "d": ["A phosphoenolpyruvate-dependent sugar phosphotransferase transport specific for mammosylglycerate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902168", "l": "response to catechin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900498", "l": "negative regulation of butyryl-CoA catabolic process to butanol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032739", "l": "positive regulation of interleukin-16 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-16 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046517", "l": "octamethylcyclotetrasiloxane catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051085", "l": "chaperone cofactor-dependent protein refolding", "d": ["The process of assisting in the correct posttranslational noncovalent assembly of proteins, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060010", "l": "Sertoli cell fate commitment", "d": ["The process in which the cellular identity of Sertoli cells is acquired and determined."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.545697013636541", "identifiers": [{"i": "GO:0043576", "l": "regulation of respiratory gaseous exchange", "d": ["Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051078", "l": "meiotic nuclear membrane disassembly", "d": ["The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.569439710577498", "identifiers": [{"i": "GO:0006163", "l": "purine nucleotide metabolic process", "d": ["The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070799", "l": "regulation of conidiophore stalk development", "d": ["Any process that modulates the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0002168", "l": "instar larval development", "d": ["The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. This begins with the newly hatched first-instar larva, through its maturation to the end of the last larval stage. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046188", "l": "methane catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0016130", "l": "phytosteroid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.956741683831709", "identifiers": [{"i": "GO:0061526", "l": "acetylcholine secretion", "d": ["The regulated release of acetylcholine by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:1903312", "l": "negative regulation of mRNA metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mRNA metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1902001", "l": "fatty acid transmembrane transport", "d": ["The process in which a fatty acid is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000474", "l": "regulation of opioid receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of opioid receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002667", "l": "regulation of T cell anergy", "d": ["Any process that modulates the frequency, rate, or extent of T cell anergy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905280", "l": "negative regulation of retrograde transport, endosome to Golgi", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of retrograde transport, endosome to Golgi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048297", "l": "negative regulation of isotype switching to IgA isotypes", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgA isotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.281104362693469", "identifiers": [{"i": "GO:0031399", "l": "regulation of protein modification process", "d": ["Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0090522", "l": "vesicle tethering involved in exocytosis", "d": ["The initial, indirect interaction between a secretory vesicle membrane and a site of exocytosis in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901667", "l": "negative regulation of skeletal muscle satellite cell activation involved in skeletal muscle regeneration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell activation involved in skeletal muscle regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0071295", "l": "cellular response to vitamin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015861", "l": "cytidine transport", "d": ["The directed movement of cytidine, cytosine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902913", "l": "positive regulation of neuroepithelial cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000255", "l": "allantoin metabolic process", "d": ["The chemical reactions and pathways involving allantoin, (2,5-dioxo-4-imidazolidinyl)urea, an intermediate or end product of purine catabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0093002", "l": "response to nematicide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nematicide stimulus. Nematicides are chemicals used to kill nematodes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007118", "l": "budding cell apical bud growth", "d": ["Growth at the tip of a bud, in a cell that reproduces by budding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045978", "l": "negative regulation of nucleoside metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.884204812668166", "identifiers": [{"i": "GO:0071495", "l": "cellular response to endogenous stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900611", "l": "F-9775A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of F-9775A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140024", "l": "plus-end-directed endosome transport along mitotic spindle midzone microtubule", "d": ["The directed movement of an endosome towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an endosome to a microtubule, and ends when the endosome reaches its final destination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075288", "l": "negative regulation of sporangiospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021904", "l": "dorsal/ventral neural tube patterning", "d": ["The process in which the neural tube is regionalized in the dorsoventral axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901041", "l": "positive regulation of peptide antigen transport", "d": ["Any process that activates or increases the frequency, rate or extent of peptide antigen transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0071711", "l": "basement membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070584", "l": "mitochondrion morphogenesis", "d": ["The process in which the anatomical structures of a mitochondrion are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903286", "l": "regulation of potassium ion import", "d": ["Any process that modulates the frequency, rate or extent of potassium ion import."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902612", "l": "regulation of anti-Mullerian hormone signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of anti-Mullerian hormone signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903728", "l": "luteal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a luteal cell. Large luteal cells develop from granulosa cells. Small luteal cells develop from theca cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019294", "l": "keto-3-deoxy-D-manno-octulosonic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002872", "l": "negative regulation of natural killer cell tolerance induction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.314728742240533", "identifiers": [{"i": "GO:0002698", "l": "negative regulation of immune effector process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021657", "l": "rhombomere 2 formation", "d": ["The process that gives rise to rhombomere 2. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072715", "l": "cellular response to selenite ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0036465", "l": "synaptic vesicle recycling", "d": ["The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902864", "l": "negative regulation of embryonic camera-type eye development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.585103934178449", "identifiers": [{"i": "GO:0016125", "l": "sterol metabolic process", "d": ["The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071492", "l": "cellular response to UV-A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904779", "l": "regulation of protein localization to centrosome", "d": ["Any process that modulates the frequency, rate or extent of protein localization to centrosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0040004", "l": "collagen and cuticulin-based cuticle attachment to epithelium", "d": ["Attaching of a collagen and cuticulin-based cuticle to the epithelium underlying it. An example of this process is found in Caenorhabditis elegans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.180129424388433", "identifiers": [{"i": "GO:0040011", "l": "locomotion", "d": ["Self-propelled movement of a cell or organism from one location to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0099622", "l": "cardiac muscle cell membrane repolarization", "d": ["The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010583", "l": "response to cyclopentenone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0000378", "l": "RNA exon ligation", "d": ["The RNA metabolic process that joins two exons, each of which has free ends that were generated by endonucleolytic cleavages, by a ligation reaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042673", "l": "regulation of retinal cone cell fate specification", "d": ["Any process that mediates the specification of a cell into a retinal cone cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903908", "l": "positive regulation of plasma membrane raft polarization", "d": ["Any process that activates or increases the frequency, rate or extent of plasma membrane raft polarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0050680", "l": "negative regulation of epithelial cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0001832", "l": "blastocyst growth", "d": ["An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015741", "l": "fumarate transport", "d": ["The directed movement of fumarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000954", "l": "regulation of cyclodextrin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cyclodextrin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0009793", "l": "embryo development ending in seed dormancy", "d": ["The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0051316", "l": "attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation", "d": ["The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex contributing to meiotic chromosome segregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905697", "l": "negative regulation of polysome binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of polysome binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0032623", "l": "interleukin-2 production", "d": ["The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060952", "l": "cardiac glial cell development", "d": ["The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070178", "l": "D-serine metabolic process", "d": ["The chemical reactions and pathways involving D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900788", "l": "pseurotin A metabolic process", "d": ["The chemical reactions and pathways involving pseurotin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050650", "l": "chondroitin sulfate proteoglycan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032625", "l": "interleukin-21 production", "d": ["The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070239", "l": "regulation of activated T cell autonomous cell death", "d": ["Any process that modulates the occurrence or rate of activated T cell autonomous cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0006409", "l": "tRNA export from nucleus", "d": ["The directed movement of tRNA from the nucleus to the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072205", "l": "metanephric collecting duct development", "d": ["The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002311", "l": "gamma-delta T cell proliferation involved in immune response", "d": ["The expansion of a gamma-delta T cell population by cell division as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0034643", "l": "establishment of mitochondrion localization, microtubule-mediated", "d": ["The directed movement of the mitochondrion to a specific location, by a process involving microtubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901966", "l": "regulation of cellular response to iron ion starvation", "d": ["Any process that modulates the frequency, rate or extent of cellular response to iron ion starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010782", "l": "proboscis morphogenesis, labial disc-derived", "d": ["The process in which the anatomical structures of the proboscis that are derived from the labial disc are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.824513090543306", "identifiers": [{"i": "GO:0071466", "l": "cellular response to xenobiotic stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0017143", "l": "insecticide metabolic process", "d": ["The chemical reactions and pathways involving insecticides, chemicals used to kill insects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097370", "l": "protein O-GlcNAcylation via threonine", "d": ["The glycosylation of a protein by addition of N-acetylglucosamine via the O3 atom of peptidyl-threonine, forming O3-N-acetylglucosamine-L-threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014893", "l": "response to rest involved in regulation of muscle adaptation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rest stimulus. This process occurs as part of the regulation of muscle adaptation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010115", "l": "regulation of abscisic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002670", "l": "regulation of B cell anergy", "d": ["Any process that modulates the frequency, rate, or extent of B cell anergy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099043", "l": "cargo loading involved in clathrin-dependent endocytosis", "d": ["Formation of a macromolecular complex during clathrin-dependent endocytosis that connects the assembling clathrin coat to the proteins and/or lipoproteins to be transported in an endocytic vesicle. This complex includes a receptor and an adaptor protein that links the receptor to the clathrin coat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0033240", "l": "positive regulation of amine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035493", "l": "SNARE complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1900371", "l": "regulation of purine nucleotide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of purine nucleotide biosynthetic processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0001657", "l": "ureteric bud development", "d": ["The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903854", "l": "negative regulation of stress response to copper ion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of stress response to copper ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060524", "l": "dichotomous subdivision of prostate epithelial cord terminal unit", "d": ["The process in which a prostate epithelial cord bifurcates at its end."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0019720", "l": "Mo-molybdopterin cofactor metabolic process", "d": ["The chemical reactions and pathways involving the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042501", "l": "serine phosphorylation of STAT protein", "d": ["The process of introducing a phosphate group to a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001269", "l": "positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0009134", "l": "nucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0071501", "l": "cellular response to sterol depletion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032020", "l": "ISG15-protein conjugation", "d": ["The covalent addition to a protein of ISG15, a ubiquitin-like protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0002884", "l": "negative regulation of hypersensitivity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046116", "l": "queuosine metabolic process", "d": ["The chemical reactions and pathways involving queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060596", "l": "mammary placode formation", "d": ["The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030466", "l": "silent mating-type cassette heterochromatin formation", "d": ["Repression of transcription at silent mating-type loci by alteration of the structure of chromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007385", "l": "specification of segmental identity, abdomen", "d": ["The specification of the characteristic structures of the abdominal segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003004", "l": "follicular fluid formation in ovarian follicle antrum involved in distinct antral spaces stage", "d": ["The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the antral spaces stage of oogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0046149", "l": "pigment catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a pigment, any general or particular coloring matter in living organisms, e.g. melanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905329", "l": "sphingoid long-chain base transport", "d": ["The directed movement of a sphingoid long-chain base, sometimes referred to as long-chain base, or sphingoid base, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sphingoid long-chain bases are long-chain aliphatic amines that are the fundamental building blocks of sphingolipids. The main mammalian sphingoid long-chain bases are dihydrosphingosine and sphingosine, while dihydrosphingosine and phytosphingosine are the main sphingoid long-chain bases in yeast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "46.245657037398182", "identifiers": [{"i": "GO:0071705", "l": "nitrogen compound transport", "d": ["The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.62986809207635", "identifiers": [{"i": "GO:0002027", "l": "regulation of heart rate", "d": ["Any process that modulates the frequency or rate of heart contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0075133", "l": "modulation by symbiont of host calcium or calmodulin-mediated signal transduction", "d": ["Any process in which the symbiont modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002428", "l": "antigen processing and presentation of peptide antigen via MHC class Ib", "d": ["The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC class Ib protein complex on its cell surface. The peptide antigen may originate from an endogenous or exogenous protein. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E family."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030150", "l": "protein import into mitochondrial matrix", "d": ["The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006666", "l": "3-keto-sphinganine metabolic process", "d": ["The chemical reactions and pathways involving 3-keto-sphinganine, a derivative of sphinganine with a ketone group at C3. It is an intermediate in the synthesis of sphingosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903365", "l": "regulation of fear response", "d": ["Any process that modulates the frequency, rate or extent of fear response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072246", "l": "metanephric glomerular parietal epithelial cell development", "d": ["The process whose specific outcome is the progression of a metanephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0034370", "l": "triglyceride-rich lipoprotein particle remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within a triglyceride-rich lipoprotein particle, including the hydrolysis of triglyceride by lipoprotein lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride from a triglyceride-rich lipoprotein particle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990687", "l": "endoplasmic reticulum-derived vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane", "d": ["The joining of the lipid bilayer membrane around an endoplasmic reticulum-derived vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPII-coated transport vesicles involved in anterograde transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001830", "l": "trophectodermal cell fate commitment", "d": ["The cell fate commitment of precursor cells that will become trophectoderm cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901022", "l": "4-hydroxyphenylacetate metabolic process", "d": ["The chemical reactions and pathways involving 4-hydroxyphenylacetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901201", "l": "regulation of extracellular matrix assembly", "d": ["Any process that modulates the frequency, rate or extent of extracellular matrix assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071051", "l": "polyadenylation-dependent snoRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0046113", "l": "nucleobase catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0086068", "l": "Purkinje myocyte to ventricular cardiac muscle cell communication", "d": ["The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060792", "l": "sweat gland development", "d": ["The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021977", "l": "tectospinal tract morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060665", "l": "regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling", "d": ["Any process that modulates the rate, frequency, or extent of branching involved in salivary gland morphogenesis as a result of signals being generated by the mesenchyme and received and interpreted by the salivary gland epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036368", "l": "cone photoresponse recovery", "d": ["The processes required for a cone photoreceptor to recover, following light activation, so that it can respond to a subsequent light stimulus. Cone recovery requires the shutoff of active participants in the phototransduction cascade, including the visual pigment and downstream signal transducers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010264", "l": "myo-inositol hexakisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904646", "l": "cellular response to amyloid-beta", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032976", "l": "release of matrix enzymes from mitochondria", "d": ["The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol, as part of the apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903284", "l": "positive regulation of glutathione peroxidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of glutathione peroxidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060282", "l": "positive regulation of oocyte development", "d": ["Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905587", "l": "positive regulation of outer hair cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of outer hair cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009290", "l": "DNA import into cell involved in transformation", "d": ["The directed movement of DNA into a cell that contributes to the process of transformation, the uptake of foreign genetic material into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070408", "l": "carbamoyl phosphate metabolic process", "d": ["The chemical reactions and pathways involving carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902181", "l": "verruculogen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of verruculogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090394", "l": "negative regulation of excitatory postsynaptic potential", "d": ["Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060275", "l": "maintenance of stationary phase in response to starvation", "d": ["The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to limited nutrients in the environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0002828", "l": "regulation of type 2 immune response", "d": ["Any process that modulates the frequency, rate, or extent of a type 2 immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060930", "l": "sinoatrial node cell fate commitment", "d": ["The commitment of cells to sinoatrial (SA) node cell fates and their capacity to differentiate into SA node cells. SA node cells are pacemaker cells that are found in the sinoatrial node."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032515", "l": "negative regulation of phosphoprotein phosphatase activity", "d": ["Any process that stops or reduces the activity of a phosphoprotein phosphatase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046653", "l": "tetrahydrofolate metabolic process", "d": ["The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071655", "l": "regulation of granulocyte colony-stimulating factor production", "d": ["Any process that modulates the frequency, rate, or extent of production of granulocyte colony-stimulating factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010666", "l": "positive regulation of cardiac muscle cell apoptotic process", "d": ["Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090139", "l": "mitochondrial chromosome packaging", "d": ["A process in which mitochondrial chromosomal DNA and associated proteins organize into a compact, orderly structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000675", "l": "negative regulation of type B pancreatic cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000037", "l": "regulation of stomatal complex patterning", "d": ["Any process that modulates the frequency, rate or extent of stomatal complex patterning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046771", "l": "viral budding from inner nuclear membrane", "d": ["The envelopment of a virus, in which the nucleocapsid evaginates from the host inner nuclear membrane system into the perinuclear space, thus acquiring a membrane envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0071934", "l": "thiamine transmembrane transport", "d": ["The process in which thiamine is transported across a membrane. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0006882", "l": "intracellular zinc ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of zinc ions within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000101", "l": "sulfur amino acid transport", "d": ["The directed movement of amino acids containing sulfur (cystine, methionine and their derivatives) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900557", "l": "emericellamide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of emericellamide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901229", "l": "regulation of non-canonical Wnt signaling pathway via JNK cascade", "d": ["Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901606", "l": "alpha-amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905597", "l": "positive regulation of low-density lipoprotein particle receptor binding", "d": ["Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle receptor binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072125", "l": "negative regulation of glomerular mesangial cell proliferation", "d": ["Any process that decreases the frequency, rate or extent of glomerular mesangial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061223", "l": "mesonephric mesenchymal cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the mesonephros as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070901", "l": "mitochondrial tRNA methylation", "d": ["The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015856", "l": "cytosine transport", "d": ["The directed movement of cytosine, 4-amino-2-hydroxypyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061557", "l": "trigeminal ganglion maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905794", "l": "response to puromycin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.161881760686384", "identifiers": [{"i": "GO:0010566", "l": "regulation of ketone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901035", "l": "negative regulation of L-glutamine import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine import into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070343", "l": "white fat cell proliferation", "d": ["The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:2000649", "l": "regulation of sodium ion transmembrane transporter activity", "d": ["Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006660", "l": "phosphatidylserine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070957", "l": "negative regulation of neutrophil mediated killing of gram-negative bacterium", "d": ["Any process that decreases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048442", "l": "sepal development", "d": ["The process whose specific outcome is the progression of the sepal over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0046777", "l": "protein autophosphorylation", "d": ["The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0044659", "l": "viral release from host cell by cytolysis", "d": ["The dissemination of mature viral particles from a host cell by the rupture of cell membranes and the loss of cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0051712", "l": "positive regulation of killing of cells of another organism", "d": ["Any process that activates or increases the frequency, rate or extent of the killing by an organism of cells in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0000409", "l": "regulation of transcription by galactose", "d": ["Any process involving galactose that modulates the frequency, rate or extent or transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0001978", "l": "regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback", "d": ["The process that modulates blood pressure by sensing the amount of stretch occurring in large arteries and responding to the input via central nervous system control."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1903416", "l": "response to glycoside", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoside stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.651613913496419", "identifiers": [{"i": "GO:0009812", "l": "flavonoid metabolic process", "d": ["The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivatives containing a flavan skeleton including flavones, flavonols and flavanoids, and anthocyanins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043149", "l": "stress fiber assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a stress fiber. A stress fiber is a contractile actin filament bundle that consists of short actin filaments with alternating polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0001748", "l": "insect visual primordium development", "d": ["The process whose specific outcome is the progression of the optic placode over time, from its formation to the mature structure. During embryonic stage 12 the placode starts to invaginate, forming a pouch. Cells that will form Bolwig's organ segregate from the ventral lip of this pouch, remaining in the head epidermis. The remainder of the invagination loses contact with the outer surface and becomes the optic lobe. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021871", "l": "forebrain regionalization", "d": ["The regionalization process resulting in the creation of areas within the forebrain that will direct the behavior of cell migration in differentiation as the forebrain develops."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0046125", "l": "pyrimidine deoxyribonucleoside metabolic process", "d": ["The chemical reactions and pathways involving any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0016048", "l": "detection of temperature stimulus", "d": ["The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1902253", "l": "regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "d": ["Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042836", "l": "D-glucarate metabolic process", "d": ["The chemical reactions and pathways involving D-glucarate, the D-enantiomer of glucarate. D-glucarate is derived from either D-glucose or L-gulose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0034756", "l": "regulation of iron ion transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006896", "l": "Golgi to vacuole transport", "d": ["The directed movement of substances from the Golgi to the vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0060487", "l": "lung epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0050665", "l": "hydrogen peroxide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0033108", "l": "mitochondrial respiratory chain complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031555", "l": "transcriptional attenuation", "d": ["A negative regulation of gene expression mechanism by which bacteria and archae can direct RNA polymerase to prematurely terminate transcription in response to a specific metabolic signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0048681", "l": "negative regulation of axon regeneration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "42.692735976176017", "identifiers": [{"i": "GO:0046903", "l": "secretion", "d": ["The controlled release of a substance by a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0090500", "l": "endocardial cushion to mesenchymal transition", "d": ["A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0098764", "l": "meiosis I cell cycle phase", "d": ["A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.892466024748572", "identifiers": [{"i": "GO:0071555", "l": "cell wall organization", "d": ["A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060856", "l": "establishment of blood-brain barrier", "d": ["Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044830", "l": "modulation by host of viral RNA genome replication", "d": ["A process in which a host organism modulates the frequency, rate or extent of viral RNA genome replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902736", "l": "positive regulation of receptor-mediated virion attachment to host cell", "d": ["Any process that activates or increases the frequency, rate or extent of receptor-mediated virion attachment to host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901852", "l": "7,8-didemethyl-8-hydroxy-5-deazariboflavin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 7,8-didemethyl-8-hydroxy-5-deazariboflavin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072637", "l": "interleukin-32 production", "d": ["The appearance of interleukin-32 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0046519", "l": "sphingoid metabolic process", "d": ["The chemical reactions and pathways involving sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009961", "l": "response to 1-aminocyclopropane-1-carboxylic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900071", "l": "regulation of sulfite transport", "d": ["Any process that modulates the frequency, rate or extent of sulfite transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060813", "l": "anterior mRNA localization involved in anterior/posterior axis specification", "d": ["Any process in which a mRNA is transported to, and maintained in the anterior portion of the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904629", "l": "response to diterpene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018159", "l": "peptidyl-methionine oxidation", "d": ["The oxidation of peptidyl-L-methionine to peptidyl-L-methionine sulfone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070886", "l": "positive regulation of calcineurin-NFAT signaling cascade", "d": ["Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0033967", "l": "box C/D RNA metabolic process", "d": ["The chemical reactions and pathways involving box C/D type small nucleolar RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072580", "l": "bacterial-type EF-P lysine modification", "d": ["The modification of a lysine residue in a protein to produce (2S)-2-amino-6-([(3S)-3,6-diaminohexanoyl]amino)hexanoic acid, and the subsequent hydroxylation of the modified lysine residue. This modification is observed in, and is probably unique to, the prokaryotic translation elongation factor P (EF-P)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010642", "l": "negative regulation of platelet-derived growth factor receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072735", "l": "response to tert-butyl hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051796", "l": "negative regulation of timing of catagen", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036531", "l": "glutathione deglycation", "d": ["The removal of a sugar or dicarbonyl from glycated glutathione. Glutathione is the tripeptide glutamylcysteinylglycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900450", "l": "negative regulation of glutamate receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glutamate receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.566286445527851", "identifiers": [{"i": "GO:0060326", "l": "cell chemotaxis", "d": ["The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031619", "l": "homologous chromosome orientation involved in meiotic metaphase I plate congression", "d": ["The cell cycle process in which the sister centromeres of one chromosome attach to microtubules that emanate from the same spindle pole, which ensures that homologous maternal and paternal chromosomes are pulled in opposite directions at anaphase of meiosis I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900769", "l": "fonsecin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fonsecin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000282", "l": "cellular bud site selection", "d": ["The specification of the site where a daughter cell will form, in organisms that reproduce by budding. An example of this process is found in Saccharomyces cerevisiae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043569", "l": "negative regulation of insulin-like growth factor receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of insulin-like growth factor receptor signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.26089068872632", "identifiers": [{"i": "GO:0060349", "l": "bone morphogenesis", "d": ["The process in which bones are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0003431", "l": "growth plate cartilage chondrocyte development", "d": ["The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043456", "l": "regulation of pentose-phosphate shunt", "d": ["Any process that modulates the frequency, rate or extent of the pentose-phosphate shunt, the process in which glucose is oxidized, coupled to NADPH synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.582174935760108", "identifiers": [{"i": "GO:1902476", "l": "chloride transmembrane transport", "d": ["The process in which chloride is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0019418", "l": "sulfide oxidation", "d": ["The chemical reactions and pathways resulting in the conversion of sulfide to elemental sulfur in a higher oxidation state, or to sulfite or sulfate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140547", "l": "acquisition of seed longevity", "d": ["The acquisition of seed longevity is the ordered series of events during seed development, that prevent embryo deterioration and ROS damage and thus contribute to seed viability over time or in response to adverse environmental conditions. These events include protective (e.g. production of glassy cytoplasm ) and repair (e.g. oxidative stress responses) processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0110057", "l": "regulation of blood vessel endothelial cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003166", "l": "bundle of His development", "d": ["The process whose specific outcome is the progression of the bundle of His over time, from its formation to the mature structure. The bundle of His is part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035708", "l": "interleukin-4-dependent isotype switching to IgE isotypes", "d": ["The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus, that is dependent on the activity of interleukin 4 (IL-4)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000222", "l": "positive regulation of pseudohyphal growth", "d": ["Any process that activates or increases the frequency, rate or extent of pseudohyphal growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002635", "l": "negative regulation of germinal center formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903096", "l": "protein localization to meiotic spindle midzone", "d": ["A process in which a protein is transported to, or maintained in, a location within a meiotic spindle midzone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0016574", "l": "histone ubiquitination", "d": ["The modification of histones by addition of ubiquitin groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0032106", "l": "positive regulation of response to extracellular stimulus", "d": ["Any process that activates, maintains or increases the rate of a response to an extracellular stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904567", "l": "response to wortmannin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.411753859901495", "identifiers": [{"i": "GO:0044042", "l": "glucan metabolic process", "d": ["The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000932", "l": "positive regulation of cellobiose metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellobiose metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035699", "l": "T-helper 17 cell extravasation", "d": ["The migration of a T-helper 17 cell from the blood vessels into the surrounding tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002556", "l": "serotonin secretion by basophil", "d": ["The regulated release of serotonin by a basophil or group of basophils."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0014822", "l": "detection of wounding", "d": ["The series of events by which an injury stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035712", "l": "T-helper 2 cell activation", "d": ["The change in morphology and behavior of a T helper 2 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0072377", "l": "blood coagulation, common pathway", "d": ["A protein activation cascade that contributes to blood coagulation and consists of events leading from the formation of activated factor X to the formation of active thrombin, the cleavage of fibrinogen by thrombin, and the formation of cleaved fibrin into a stable multimeric, cross-linked complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060609", "l": "apoptotic process involved in tube lumen cavitation", "d": ["Any apoptotic process that contributes to the hollowing out of an epithelial rod or cord to form the central hole in a tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060997", "l": "dendritic spine morphogenesis", "d": ["The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033148", "l": "positive regulation of intracellular estrogen receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903796", "l": "negative regulation of inorganic anion transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of inorganic anion transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097054", "l": "L-glutamate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0031639", "l": "plasminogen activation", "d": ["The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051029", "l": "rRNA transport", "d": ["The directed movement of rRNA, ribosomal ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002625", "l": "regulation of T cell antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002015", "l": "regulation of systemic arterial blood pressure by atrial baroreceptor feedback", "d": ["A process that controls blood pressure by sensing the amount of stretch occurring in the atria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072277", "l": "metanephric glomerular capillary formation", "d": ["The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.232064878529073", "identifiers": [{"i": "GO:0042327", "l": "positive regulation of phosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905430", "l": "cellular response to glycine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010139", "l": "pyrimidine deoxyribonucleotide salvage", "d": ["The pathway by which pyrimidine bases or pyrimidine deoxyribonucleotides from pyrimidine nucleotide breakdown are converted back to pyrimidine deoxyribonucleotides. The salvage pathway is important where there is no de novo pyrimidine deoxyribonucleotide biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000049", "l": "positive regulation of cell-cell adhesion mediated by cadherin", "d": ["Any process that activates or increases the frequency, rate or extent of cell-cell adhesion mediated by cadherin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043054", "l": "dauer exit", "d": ["Exit from the facultative diapause of the dauer (enduring) larval stage of nematode development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046918", "l": "N-terminal peptidyl-glycine N-palmitoylation", "d": ["The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal glycine residue to form N-palmitoyl-glycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060083", "l": "smooth muscle contraction involved in micturition", "d": ["The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072140", "l": "DCT cell development", "d": ["The process whose specific outcome is the progression of a distal convoluted tubule cell over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045958", "l": "positive regulation of complement activation, alternative pathway", "d": ["Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901181", "l": "negative regulation of cellular response to caffeine", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to caffeine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071649", "l": "regulation of chemokine (C-C motif) ligand 5 production", "d": ["Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0018206", "l": "peptidyl-methionine modification", "d": ["The modification of peptidyl-methionine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034462", "l": "small-subunit processome assembly", "d": ["The aggregation, arrangement and bonding together of proteins and RNA molecules to form a small-subunit processome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106342", "l": "omega-hydroxyceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of omega-hydroxyceramide/acylceramide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901920", "l": "peptidyl-tyrosine dephosphorylation involved in activation of protein kinase activity", "d": ["Any peptidyl-tyrosine dephosphorylation that is involved in activation of protein kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000292", "l": "regulation of defecation", "d": ["Any process that modulates the frequency, rate or extent of defecation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903678", "l": "negative regulation of cap-independent translational initiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cap-independent translational initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1900449", "l": "regulation of glutamate receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002570", "l": "somatic diversification of immunoglobulin genes by N region addition", "d": ["The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin genes. N regions are found at the V-D and D-J recombinational junctions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001998", "l": "angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure", "d": ["The decrease in blood vessel diameter as a result of the release of angiotensin into the blood stream."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042081", "l": "GSI anchor metabolic process", "d": ["The chemical reactions and pathways involving glycosylsphingolipidinositol (GSI) anchors, which attach membrane proteins to the lipid bilayer of the cell membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006028", "l": "galactosaminoglycan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.582174935760108", "identifiers": [{"i": "GO:0030183", "l": "B cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045014", "l": "carbon catabolite repression of transcription by glucose", "d": ["A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0043587", "l": "tongue morphogenesis", "d": ["The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046288", "l": "isoflavonoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099575", "l": "regulation of protein catabolic process at presynapse, modulating synaptic transmission", "d": ["Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097484", "l": "dendrite extension", "d": ["Long distance growth of a single dendrite involved in cellular development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045050", "l": "protein insertion into ER membrane by stop-transfer membrane-anchor sequence", "d": ["A process of protein insertion into the endoplasmic reticulum (ER) membrane in which stop-transfer membrane-anchor sequences become an ER membrane spanning helix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032823", "l": "regulation of natural killer cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of natural killer cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060621", "l": "negative regulation of cholesterol import", "d": ["Any process that decreases the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0030168", "l": "platelet activation", "d": ["A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:0034599", "l": "cellular response to oxidative stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019368", "l": "fatty acid elongation, unsaturated fatty acid", "d": ["Elongation of a fatty acid chain into which one or more C-C double bonds have been introduced."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903496", "l": "response to 11-deoxycorticosterone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0046638", "l": "positive regulation of alpha-beta T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of alpha-beta T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905641", "l": "cellular response to acetaldehyde", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904781", "l": "positive regulation of protein localization to centrosome", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to centrosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001030", "l": "negative regulation of cellular glucuronidation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular glucuronidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903033", "l": "positive regulation of microtubule plus-end binding", "d": ["Any process that activates or increases the frequency, rate or extent of microtubule plus-end binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902336", "l": "positive regulation of retinal ganglion cell axon guidance", "d": ["Any process that activates or increases the frequency, rate or extent of retinal ganglion cell axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0007343", "l": "egg activation", "d": ["The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021769", "l": "orbitofrontal cortex development", "d": ["The progression of the orbitofrontal cortex over time from its initial formation until its mature state. The orbitofrontal cortex is a cerebral cortex region located in the frontal lobe."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072250", "l": "metanephric podocyte cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0048199", "l": "vesicle targeting, to, from or within Golgi", "d": ["The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900725", "l": "osmoregulated periplasmic glucan metabolic process", "d": ["The chemical reactions and pathways involving osmoregulated periplasmic glucan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905846", "l": "regulation of cellular response to oxidopamine", "d": ["Any process that modulates the frequency, rate or extent of cellular response to oxidopamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905669", "l": "TORC1 complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a TORC1 complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000914", "l": "positive regulation of galactoglucomannan catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of galactoglucomannan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904372", "l": "positive regulation of protein localization to actin cortical patch", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to actin cortical patch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018938", "l": "2-nitropropane metabolic process", "d": ["The chemical reactions and pathways involving 2-nitropropane, a clear, colorless liquid with a mild, fruity odor. 2-nitropropane is used principally as a solvent and chemical intermediate. As a solvent, it is used in inks, paints, adhesives, varnishes, polymers, and synthetic materials. It is a feedstock for the manufacture of 2-nitro-2-methyl-1-propanol and 2-amino-2-methyl-1-propanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0090153", "l": "regulation of sphingolipid biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901439", "l": "positive regulation of toluene metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of toluene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0052158", "l": "modulation by symbiont of host resistance gene-dependent defense response", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002816", "l": "regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria", "d": ["Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990120", "l": "messenger ribonucleoprotein complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins and messenger RNA (mRNA) molecules to form a messenger ribonucleoprotein (mRNP) complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019586", "l": "galacturonate metabolic process", "d": ["The chemical reactions and pathways involving galacturonate, the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000535", "l": "regulation of entry of bacterium into host cell", "d": ["Any process that modulates the frequency, rate or extent of entry of bacterium into host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010516", "l": "negative regulation of cellular response to nitrogen starvation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular response to nitrogen starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060999", "l": "positive regulation of dendritic spine development", "d": ["Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905040", "l": "otic placode development", "d": ["The process whose specific outcome is the progression of an otic placode over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0100010", "l": "positive regulation of fever generation by prostaglandin biosynthetic process", "d": ["Any prostaglandin biosynthetic process process that positively_regulates fever generation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0051761", "l": "sesquiterpene metabolic process", "d": ["The chemical reactions and pathways involving sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048379", "l": "positive regulation of lateral mesodermal cell fate specification", "d": ["Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097534", "l": "lymphoid lineage cell migration", "d": ["The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900953", "l": "regulation of 18-methylnonadec-1-ene metabolic process", "d": ["Any process that modulates the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905551", "l": "negative regulation of protein localization to endoplasmic reticulum", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002871", "l": "regulation of natural killer cell tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.527781272052167", "identifiers": [{"i": "GO:0060606", "l": "tube closure", "d": ["Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031542", "l": "positive regulation of anthocyanin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0051315", "l": "attachment of mitotic spindle microtubules to kinetochore", "d": ["The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097333", "l": "response to olanzapine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an olanzapine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0099084", "l": "postsynaptic specialization organization", "d": ["A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic specialization, a structure that lies adjacent to the cytoplasmic face of the postsynaptic membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0070570", "l": "regulation of neuron projection regeneration", "d": ["Any process that modulates the rate, frequency or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031107", "l": "septin ring disassembly", "d": ["The controlled breakdown of a septin ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071226", "l": "cellular response to molecule of fungal origin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019301", "l": "rhamnose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014021", "l": "secondary neural tube formation", "d": ["The formation of the neural tube by coalescence of mesenchymal cells followed by their conversion to epithelial cells to form a solid cord that subsequently hollows out (cavitates) to create a hollow tube. Secondary neurulation is the typical mechanism of formation of the neural tube posterior to the posterior neuropore in mammals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000258", "l": "negative regulation of protein activation cascade", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein activation cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000379", "l": "tRNA-type intron splice site recognition and cleavage", "d": ["RNA processing that begins when the tertiary structure of a tRNA type intron is recognized, and ends when the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901784", "l": "p-cresol metabolic process", "d": ["The chemical reactions and pathways involving p-cresol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903378", "l": "positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018947", "l": "anaerobic organosilicon metabolic process", "d": ["The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061936", "l": "fusion of sperm to egg plasma membrane involved in double fertilization forming a zygote and endosperm", "d": ["The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming a zygote and endosperm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000707", "l": "positive regulation of dense core granule biogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of dense core granule biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000908", "l": "positive regulation of glucomannan catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of glucomannan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036058", "l": "filtration diaphragm assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a filtration diaphragm, a specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904343", "l": "positive regulation of colon smooth muscle contraction", "d": ["Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000374", "l": "Group III intron splicing", "d": ["The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902790", "l": "undecan-2-one metabolic process", "d": ["The chemical reactions and pathways involving undecan-2-one."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0072337", "l": "modified amino acid transport", "d": ["The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007065", "l": "male meiosis sister chromatid cohesion", "d": ["The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a male."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903242", "l": "regulation of cardiac muscle hypertrophy in response to stress", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle hypertrophy in response to stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071661", "l": "regulation of granzyme B production", "d": ["Any process that modulates the frequency, rate, or extent of production of granzyme B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000689", "l": "actomyosin contractile ring assembly actin filament organization", "d": ["An actin filament organization process that contributes to actomyosin contractile ring assembly during cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0002276", "l": "basophil activation involved in immune response", "d": ["A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048299", "l": "regulation of isotype switching to IgD isotypes", "d": ["Any process that modulates the frequency, rate or extent of isotype switching to IgD isotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090218", "l": "positive regulation of lipid kinase activity", "d": ["Any process that increases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0000963", "l": "mitochondrial RNA processing", "d": ["The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901247", "l": "negative regulation of lung ciliated cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045478", "l": "fusome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome, a large intracellular spectrin-rich structure found in insect germline cells and mammalian hematopoietic cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045847", "l": "negative regulation of nitrogen utilization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of nitrogen utilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900823", "l": "negative regulation of ergot alkaloid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ergot alkaloid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048891", "l": "lateral line ganglion neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a lateral line ganglion neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.569439710577498", "identifiers": [{"i": "GO:0034766", "l": "negative regulation of monoatomic ion transmembrane transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902091", "l": "negative regulation of fumagillin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fumagillin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071313", "l": "cellular response to caffeine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0018955", "l": "phenanthrene metabolic process", "d": ["The chemical reactions and pathways involving phenanthrene, a tricyclic aromatic hydrocarbon used in explosives and in the synthesis of dyes and drugs. Although phenanthrene is not mutagenic or carcinogenic, it has been shown to be toxic to marine diatoms, gastropods, mussels, crustaceans, and fish."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000632", "l": "negative regulation of pre-miRNA processing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pre-microRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046011", "l": "regulation of oskar mRNA translation", "d": ["Any process that modulates the frequency, rate or extent of oskar mRNA translation. To ensure the localization of Oskar protein at the posterior pole of the oocyte, translation of oskar mRNA is repressed during its transport to the posterior pole and activated upon localization of the mRNA at the posterior cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010418", "l": "rhamnogalacturonan II backbone metabolic process", "d": ["The chemical reactions and pathways involving the backbone structure of pectic rhamnogalacturonan II. The back bone contains at least 8 1,4-linked alpha-D-GalpA residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.642927237245431", "identifiers": [{"i": "GO:0001696", "l": "gastric acid secretion", "d": ["The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052162", "l": "modulation by symbiont of defense-related host calcium ion flux", "d": ["Any process in which an organism modulates the frequency, rate or extent of calcium ion fluxes as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061230", "l": "mesonephric juxtaglomerulus cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric juxtaglomerulus cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905204", "l": "negative regulation of connective tissue replacement", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of connective tissue replacement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002205", "l": "somatic hypermutation of immunoglobulin genes involved in immune response", "d": ["Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins following the induction of and contributing to an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070297", "l": "regulation of phosphorelay signal transduction system", "d": ["Any process that modulates the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905646", "l": "positive regulation of FACT complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of FACT complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045327", "l": "protein-DNA covalent cross-linking via peptidyl-tyrosine", "d": ["The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0080190", "l": "lateral growth", "d": ["Growth of a plant axis (shoot axis or root) that originates from a lateral meristem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001123", "l": "maltoheptaose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a maltoheptaose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0034390", "l": "smooth muscle cell apoptotic process", "d": ["Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0015791", "l": "polyol transmembrane transport", "d": ["The directed movement of polyols, any polyhydric alcohol, across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.651613913496419", "identifiers": [{"i": "GO:0009119", "l": "ribonucleoside metabolic process", "d": ["The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048626", "l": "myoblast fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.892466024748572", "identifiers": [{"i": "GO:0002577", "l": "regulation of antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.815303035410999", "identifiers": [{"i": "GO:0048871", "l": "multicellular organismal-level homeostasis", "d": ["Any process involved in the maintenance of an internal steady state at the level of the multicellular organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0046184", "l": "aldehyde biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aldehydes, any organic compound with the formula R-CH=O."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901772", "l": "lincomycin metabolic process", "d": ["The chemical reactions and pathways involving lincomycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106060", "l": "regulation of exit from meiosis", "d": ["Any process that modulates the frequency, rate or extent of exit from mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017013", "l": "protein flavinylation", "d": ["The addition of a flavin group to a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0043983", "l": "histone H4-K12 acetylation", "d": ["The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032149", "l": "response to rhamnose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903740", "l": "positive regulation of phosphatidate phosphatase activity", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidate phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042786", "l": "evasion of host immune response via modulation of host antigen processing and presentation", "d": ["Any mechanism of active immune avoidance which works by regulating the host's antigen processing or presentation pathways, e.g. by blocking any stage in MHC class II presentation. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000079", "l": "regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902669", "l": "positive regulation of axon guidance", "d": ["Any process that activates or increases the frequency, rate or extent of axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071919", "l": "G-quadruplex DNA formation", "d": ["A DNA metabolic process that results in the formation of G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad or G-quartet. The stacking of several layers of G-quartets forms G-quadruplexes, in which one or more DNA single strands are assembled in parallel and/or antiparallel, with interactions that can be either intra- or intermolecular in nature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036250", "l": "peroxisome transport along microtubule", "d": ["The directed movement of a peroxisome along a microtubule, mediated by motor proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0035934", "l": "corticosterone secretion", "d": ["The regulated release of corticosterone into the circulatory system. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0014855", "l": "striated muscle cell proliferation", "d": ["The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031591", "l": "wybutosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902834", "l": "regulation of proline import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of proline import into cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060974", "l": "cell migration involved in heart formation", "d": ["The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900641", "l": "negative regulation of austinol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of austinol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090049", "l": "regulation of cell migration involved in sprouting angiogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.664775500092716", "identifiers": [{"i": "GO:0035282", "l": "segmentation", "d": ["The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000212", "l": "negative regulation of glutamate metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of glutamate metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0010034", "l": "response to acetate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002215", "l": "defense response to nematode", "d": ["A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035543", "l": "positive regulation of SNARE complex assembly", "d": ["Any process that increases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010889", "l": "regulation of sequestering of triglyceride", "d": ["Any process that modulates the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0055119", "l": "relaxation of cardiac muscle", "d": ["The process in which the extent of cardiac muscle contraction is reduced."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0034121", "l": "regulation of toll-like receptor signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0007114", "l": "cell budding", "d": ["A form of asexual reproduction, occurring in certain bacteria and fungi (e.g. yeasts) and some primitive animals in which an individual arises from a daughter cell formed by pinching off a part of the parent cell. The budlike outgrowths so formed may sometimes remain attached to the parent cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1990180", "l": "mitochondrial tRNA 3'-end processing", "d": ["The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090029", "l": "negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion", "d": ["Any process that decreases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048685", "l": "negative regulation of collateral sprouting of intact axon in response to injury", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019097", "l": "pole plasm mitochondrial srRNA localization", "d": ["Any process in which mitochondrial small ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010674", "l": "negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle", "d": ["Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070173", "l": "regulation of enamel mineralization", "d": ["Any process that modulates the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001300", "l": "lipoxin metabolic process", "d": ["The chemical reactions and pathways involving a lipoxin. A lipoxin is a non-classic eicosanoid and signalling molecule that has four conjugated double bonds and is derived from arachidonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0043516", "l": "regulation of DNA damage response, signal transduction by p53 class mediator", "d": ["Any process that modulates the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0006890", "l": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "d": ["The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045450", "l": "bicoid mRNA localization", "d": ["Any process in which bicoid mRNA is transported to and maintained within the oocyte as part of the specification of the anterior/posterior axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018116", "l": "peptidyl-lysine adenylylation", "d": ["The adenylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-adenosine)-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001142", "l": "nicotinate transport", "d": ["The directed movement of a nicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0160063", "l": "multi-pass transmembrane protein insertion into ER membrane", "d": ["A process of protein insertion of multi-pass membrane proteins into the endoplasmic reticulum (ER) membrane. Insertion of multi-pass membrane proteins is mediated by the multi-pass translocon complex and takes place following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex to promote insertion of subsequent transmembrane regions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.075115661189081", "identifiers": [{"i": "GO:0009887", "l": "animal organ morphogenesis", "d": ["Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002349", "l": "histamine production involved in inflammatory response", "d": ["The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015964", "l": "diadenosine triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039534", "l": "negative regulation of MDA-5 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the series of the MDA-5 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050985", "l": "peptidyl-threonine sulfation", "d": ["The sulfation of peptidyl-threonine to form peptidyl-O-sulfo-L-threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001158", "l": "positive regulation of proline catabolic process to glutamate", "d": ["Any process that activates or increases the frequency, rate or extent of proline catabolic process to glutamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061126", "l": "positive regulation of positive chemotaxis to cAMP by DIF-1", "d": ["Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902065", "l": "response to L-glutamate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006424", "l": "glutamyl-tRNA aminoacylation", "d": ["The process of coupling glutamate to glutamyl-tRNA, catalyzed by glutamyl-tRNA synthetase. The glutamyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamic acid-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019258", "l": "4-nitrotoluene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 4-nitrotoluene, 1-methyl-4-nitrobenzene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002248", "l": "connective tissue replacement involved in inflammatory response wound healing", "d": ["The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared, as part of an inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033021", "l": "cyclopentanol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyclopentanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071418", "l": "cellular response to amine stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000120", "l": "positive regulation of sodium-dependent phosphate transport", "d": ["Any process that activates or increases the frequency, rate or extent of sodium-dependent phosphate transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0016135", "l": "saponin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048090", "l": "negative regulation of female pigmentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in females."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019385", "l": "methanogenesis, from acetate", "d": ["The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044759", "l": "negative regulation by symbiont of host synaptic transmission", "d": ["Any process in which a symbiont organism decreases the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903901", "l": "negative regulation of viral life cycle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of viral life cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901396", "l": "negative regulation of transforming growth factor beta2 activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta2 activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098693", "l": "regulation of synaptic vesicle cycle", "d": ["Any process that modulates the frequency, rate or extent of the synaptic vesicle cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061853", "l": "regulation of neuroblast migration", "d": ["Any process that modulates the frequency, rate or extent of neuroblast migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0001516", "l": "prostaglandin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038015", "l": "positive regulation of insulin receptor signaling pathway by insulin receptor internalization", "d": ["Any process in which internalization of an insulin receptor activates or increases the frequency, rate or extent of the insulin receptor signaling pathway. Endocytosis of activated receptors can concentrate receptors within endosomes and allow the insulin receptor to phosphorylate substrates that are spatially distinct from those accessible at the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990216", "l": "positive regulation by symbiont of host transcription", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of transcription in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0016106", "l": "sesquiterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090717", "l": "adaptive immune memory response involving T cells and B cells", "d": ["An immune response mediated by reactivated memory T cells and B cells and directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0043534", "l": "blood vessel endothelial cell migration", "d": ["The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.987832356016085", "identifiers": [{"i": "GO:0019725", "l": "cellular homeostasis", "d": ["Any process involved in the maintenance of an internal steady state at the level of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034484", "l": "raffinose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.997285155984585", "identifiers": [{"i": "GO:0009247", "l": "glycolipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006791", "l": "sulfur utilization", "d": ["A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary sulfur sources and then activates genes to scavenge the last traces of the primary sulfur source and to transport and metabolize alternate sulfur sources. The utilization process begins when the cell or organism detects sulfur levels, includes the activation of genes whose products detect, transport or metabolize sulfur-containing compounds, and ends when the sulfur is incorporated into the cell or organism's metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003177", "l": "pulmonary valve development", "d": ["The progression of the pulmonary valve over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0002475", "l": "antigen processing and presentation via MHC class Ib", "d": ["The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900395", "l": "negative regulation of kojic acid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of kojic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0003081", "l": "regulation of systemic arterial blood pressure by renin-angiotensin", "d": ["The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031116", "l": "positive regulation of microtubule polymerization", "d": ["Any process that activates or increases the frequency, rate or extent of microtubule polymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903742", "l": "regulation of anterograde synaptic vesicle transport", "d": ["Any process that modulates the frequency, rate or extent of anterograde synaptic vesicle transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905281", "l": "positive regulation of retrograde transport, endosome to Golgi", "d": ["Any process that activates or increases the frequency, rate or extent of retrograde transport, endosome to Golgi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0002820", "l": "negative regulation of adaptive immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120247", "l": "acetylenic compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000022", "l": "regulation of jasmonic acid mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of jasmonic acid mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0042386", "l": "hemocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the characteristics of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905128", "l": "positive regulation of axo-dendritic protein transport", "d": ["Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036244", "l": "cellular response to neutral pH", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0009996", "l": "negative regulation of cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from adopting a specific cell fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032228", "l": "regulation of synaptic transmission, GABAergic", "d": ["Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900918", "l": "negative regulation of octadecene metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of octadecene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007400", "l": "neuroblast fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into a neuroblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this process is found in Mus musculus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0140747", "l": "regulation of ncRNA transcription", "d": ["Any process that modulates the frequency, rate or extent of transcription of a non-protein coding gene from a DNA-template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001829", "l": "trophectodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0050672", "l": "negative regulation of lymphocyte proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061285", "l": "mesonephric capsule development", "d": ["The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900772", "l": "fumitremorgin B biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the indole alkaloid fumitremorgin B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048485", "l": "sympathetic nervous system development", "d": ["The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110123", "l": "regulation of myotube cell migration", "d": ["Any process that modulates the frequency, rate or extent of myotube cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019801", "l": "cyclization of asparagine involved in intein-mediated protein splicing", "d": ["The cyclization of asparagine to yield an L-aspartimide (otherwise known as alpha-aminosuccinimide) residue at the C-terminus of an excised intein during protein splicing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002277", "l": "myeloid dendritic cell activation involved in immune response", "d": ["The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035134", "l": "post-embryonic dorsal fin morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031413", "l": "regulation of buoyancy", "d": ["Any process that modulates an organism's tendency or ability to rise or float in a fluid medium such as water or air, often through the use of stored gases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046057", "l": "dADP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044496", "l": "negative regulation of blood pressure in another organism", "d": ["A process by which one organism decreases the force with which blood travels through the circulatory system of another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070360", "l": "actin polymerization-dependent cell migration in host", "d": ["The directional movement of an organism, usually a bacterial cell, from one place to another within its host organism, by a process involving continuous polymerization of actin at one pole of the symbiont cell. Some bacteria use host actin for migration. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0061154", "l": "endothelial tube morphogenesis", "d": ["The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0007379", "l": "segment specification", "d": ["The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.000091695522535", "identifiers": [{"i": "GO:0034654", "l": "nucleobase-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061327", "l": "anterior Malpighian tubule development", "d": ["The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080166", "l": "stomium development", "d": ["The process whose specific outcome is the progression of the stomium over time, from its formation to the mature structure. A stomium is a fissure or pore in the anther lobe through which the pollen is released."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0086042", "l": "cardiac muscle cell-cardiac muscle cell adhesion", "d": ["The attachment of one cardiomyocyte to another cardiomyocyte via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061264", "l": "mesonephric glomerular mesangial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular mesangial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045347", "l": "negative regulation of MHC class II biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0035812", "l": "renal sodium excretion", "d": ["The elimination of sodium ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060578", "l": "superior vena cava morphogenesis", "d": ["The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.825956045430587", "identifiers": [{"i": "GO:0044242", "l": "cellular lipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061288", "l": "mesonephric capsule specification", "d": ["The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032344", "l": "regulation of aldosterone metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0006857", "l": "oligopeptide transport", "d": ["The directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019503", "l": "L-proline betaine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:2001000", "l": "regulation of xylan catabolic process", "d": ["Any process that modulates the frequency, rate or extent of xylan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900161", "l": "regulation of phospholipid scramblase activity", "d": ["Any process that modulates the frequency, rate or extent of phospholipid scramblase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042797", "l": "tRNA transcription by RNA polymerase III", "d": ["The synthesis of transfer RNA (tRNA) from a DNA template by RNA polymerase III (Pol III), originating at a Pol III promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140206", "l": "dipeptide import across plasma membrane", "d": ["The directed movement of a dipeptide from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0003171", "l": "atrioventricular valve development", "d": ["The progression of the atrioventricular valve over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032699", "l": "negative regulation of interleukin-16 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-16 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000042", "l": "negative regulation of double-strand break repair via homologous recombination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of double-strand break repair via homologous recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035089", "l": "establishment of apical/basal cell polarity", "d": ["The specification and formation of the polarity of a cell along its apical/basal axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003058", "l": "hormonal regulation of the force of heart contraction", "d": ["The process in which the hormones modulates the force of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044562", "l": "envenomation resulting in negative regulation of voltage-gated potassium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation of the activity of a voltage-gated potassium channel in the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0051962", "l": "positive regulation of nervous system development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009407", "l": "toxin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009300", "l": "antisense RNA transcription", "d": ["The synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903597", "l": "negative regulation of gap junction assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gap junction assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075279", "l": "uredinium development", "d": ["The process that leads to the formation of a uredinium, a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903270", "l": "regulation of cytoplasmic translational elongation through polyproline stretches", "d": ["Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031631", "l": "negative regulation of synaptic vesicle fusion to presynaptic active zone membrane", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010704", "l": "meiotic DNA double-strand break processing involved in meiotic gene conversion", "d": ["The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang resulting in the transfer of genetic information from one helix to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010776", "l": "meiotic mismatch repair involved in meiotic gene conversion", "d": ["A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062026", "l": "negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process", "d": ["Any process that stops or decreases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140542", "l": "regulation of piRNA transcription", "d": ["Any process that modulates the frequency, rate or extent of the synthesis of a piRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0051450", "l": "myoblast proliferation", "d": ["The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036031", "l": "recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex", "d": ["The process in which the guanylyltransferase enzyme responsible for adding a 7-methylguanosine cap on pre-mRNA becomes associated with the RNA polymerase II holoenzyme complex and the 5' end of a transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0042753", "l": "positive regulation of circadian rhythm", "d": ["Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904871", "l": "positive regulation of protein localization to Cajal body", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to Cajal body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033594", "l": "response to hydroxyisoflavone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000472", "l": "negative regulation of hematopoietic stem cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0009664", "l": "plant-type cell wall organization", "d": ["A process that results in the assembly and arrangement of constituent parts of the cellulose and pectin-containing cell wall, or in the disassembly of the cellulose and pectin-containing cell wall. This process is carried out at the cellular level. An example of this process is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035675", "l": "neuromast hair cell development", "d": ["The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070298", "l": "negative regulation of phosphorelay signal transduction system", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071874", "l": "cellular response to norepinephrine stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.235616146829116", "identifiers": [{"i": "GO:0019751", "l": "polyol metabolic process", "d": ["The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0061231", "l": "mesonephric glomerulus vasculature development", "d": ["The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.855413419593077", "identifiers": [{"i": "GO:0016071", "l": "mRNA metabolic process", "d": ["The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904000", "l": "positive regulation of eating behavior", "d": ["Any process that activates or increases the frequency, rate or extent of eating behavior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990386", "l": "mitotic cleavage furrow ingression", "d": ["Advancement of the mitotic cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during mitotic cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033384", "l": "geranyl diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of geranyl diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0015732", "l": "prostaglandin transport", "d": ["The directed movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990396", "l": "single-strand break repair via homologous recombination", "d": ["The error-free repair of a single-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904360", "l": "negative regulation of spore germination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of spore germination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033535", "l": "ajugose metabolic process", "d": ["The chemical reactions and pathways involving ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075319", "l": "positive regulation of ascus development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060353", "l": "regulation of cell adhesion molecule production", "d": ["Any process that modulates the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002511", "l": "central B cell receptor editing", "d": ["Receptor editing occurring in B cells in the bone marrow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902875", "l": "regulation of embryonic pattern specification", "d": ["Any process that modulates the frequency, rate or extent of embryonic pattern specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033024", "l": "mast cell apoptotic process", "d": ["Any apoptotic process in a mast cell, a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002894", "l": "positive regulation of type II hypersensitivity", "d": ["Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099586", "l": "release of sequestered calcium ion into postsynaptic cytosol", "d": ["The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the postsynaptic cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046433", "l": "2-aminoethylphosphonate metabolic process", "d": ["The chemical reactions and pathways involving 2-aminoethylphosphonate, most abundant and ubiquitous of naturally occurring phosphonates. It is typically found as a conjugate of glycans, lipids, and proteins, which in turn perform essential biochemical functions in specialized lower organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021989", "l": "olfactory cortex development", "d": ["The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0061250", "l": "mesonephric glomerular epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0140042", "l": "lipid droplet formation", "d": ["A process that results in the assembly, arrangement of constituent parts of a lipid droplet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.990900157612501", "identifiers": [{"i": "GO:0044000", "l": "movement in host", "d": ["The process in which an organism or its progeny spreads from one location to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900833", "l": "D-leucine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-leucine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0033979", "l": "box H/ACA RNA metabolic process", "d": ["The chemical reactions and pathways involving box H/ACA type small nucleolar RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048292", "l": "isotype switching to IgD isotypes", "d": ["The switching of activated B cells from IgM biosynthesis to IgD biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgD constant region gene segments in the immunoglobulin heavy chain locus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0009821", "l": "alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902763", "l": "negative regulation of embryonic skeletal joint development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of embryonic skeletal joint development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901063", "l": "guaiacyl lignin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of guaiacyl lignin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.056588485001839", "identifiers": [{"i": "GO:0035821", "l": "modulation of process of another organism", "d": ["The process in which an organism effects a change in the structure or processes of another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000203", "l": "regulation of ribosomal large subunit export from nucleus", "d": ["Any process that modulates the frequency, rate or extent of ribosomal large subunit export from nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900002", "l": "positive regulation of anthocyanin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of anthocyanin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0061443", "l": "endocardial cushion cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:0043039", "l": "tRNA aminoacylation", "d": ["The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141062", "l": "disruption of tissue in another organism", "d": ["The disruption of the a tissue of another organism, leading to damage or temporary subversion of that tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032417", "l": "positive regulation of sodium:proton antiporter activity", "d": ["Any process that activates or increases the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0090232", "l": "positive regulation of spindle checkpoint", "d": ["Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0080029", "l": "cellular response to boron-containing substance levels", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of boron-containing substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003049", "l": "regulation of systemic arterial blood pressure by capillary fluid shift", "d": ["The intrinsic circulatory process resulting from capillary fluid shift that modulates the force with which blood travels through the systemic arterial circulatory system. Capillary fluid shift is the movement of fluid across the capillary membrane between the blood and the interstitial fluid compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990926", "l": "short-term synaptic potentiation", "d": ["The process by which synaptic transmission, induced by the arrival of a spike (action potential) at a synapse, acts to increase the amount of neurotransmitter released in response to the arrival of subsequent spikes. This effect is seen when a train of closely space spikes arrives at a synapse with a low initial release probability. It occurs in a timeframe of tens to hundreds of milliseconds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000973", "l": "post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery", "d": ["The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery even after transcription has been repressed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0044627", "l": "modulation of complement activation, classical pathway in another organism", "d": ["A process that modulates the frequency, rate or extent of the classical pathway of complement activation, in a different organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000011", "l": "vacuole inheritance", "d": ["The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140614", "l": "1,8-dihydroxynaphthalene-melanin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dihydroxy naphthalene (DHN)-melanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006114", "l": "glycerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106383", "l": "dAMP salvage", "d": ["Any process which produces a dAMP from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0036293", "l": "response to decreased oxygen levels", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904844", "l": "response to L-glutamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903178", "l": "positive regulation of tyrosine 3-monooxygenase activity", "d": ["Any process that activates or increases the frequency, rate or extent of tyrosine 3-monooxygenase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019293", "l": "tyrosine biosynthetic process, by oxidation of phenylalanine", "d": ["The conversion of phenylalanine to tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901948", "l": "5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900642", "l": "positive regulation of austinol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of austinol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071369", "l": "cellular response to ethylene stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0046513", "l": "ceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:1900910", "l": "positive regulation of olefin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of olefin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021834", "l": "chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration", "d": ["The creation and reception of signals that guide olfactory bulb interneuron precursors down concentration gradients towards the olfactory bulb."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035123", "l": "embryonic dorsal fin morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002129", "l": "wobble position guanine ribose methylation", "d": ["The process in which the ribose of guanosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140739", "l": "NLRP6 inflammasome complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a NLRP6 inflammasome complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033524", "l": "sinapate ester metabolic process", "d": ["The chemical reactions and pathways involving ester derivatives of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042695", "l": "thelarche", "d": ["The beginning of development of the breasts in the female."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099176", "l": "regulation of retrograde trans-synaptic signaling by trans-synaptic protein complex", "d": ["Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by a trans-synaptic complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0007528", "l": "neuromuscular junction development", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060786", "l": "regulation of cell differentiation involved in tissue homeostasis", "d": ["Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002909", "l": "negative regulation of peripheral B cell deletion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell deletion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0014004", "l": "microglia differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0001802", "l": "type III hypersensitivity", "d": ["An inflammatory response resulting from recognition of immune complexes via complement or Fc receptors on effector cells leading to activation of neutrophils and other leukocytes and damage to bystander tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1990928", "l": "response to amino acid starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901869", "l": "ecgonine methyl ester biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ecgonine methyl ester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046302", "l": "2-chloro-N-isopropylacetanilide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036351", "l": "histone H2A-K13 ubiquitination", "d": ["The modification of histone H2A by addition of ubiquitin group at lysine 13 (H2A-K13) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K13 and K63-linked ubiquitin chains are then extended from this monoubiquitin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045677", "l": "negative regulation of R7 cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of R7cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097010", "l": "eukaryotic translation initiation factor 4F complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 4F complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0051354", "l": "negative regulation of oxidoreductase activity", "d": ["Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.308563863677591", "identifiers": [{"i": "GO:0051094", "l": "positive regulation of developmental process", "d": ["Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.783030043623796", "identifiers": [{"i": "GO:0015918", "l": "sterol transport", "d": ["The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0035179", "l": "larval turning behavior", "d": ["Fine-tuning the spatial position of a larva in response to variability in their environment. For example, reorientation of a larva in the direction of a food source."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061017", "l": "hepatoblast differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045041", "l": "protein import into mitochondrial intermembrane space", "d": ["The import of proteins into the space between the inner and outer mitochondrial membranes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090141", "l": "positive regulation of mitochondrial fission", "d": ["Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018951", "l": "p-xylene metabolic process", "d": ["The chemical reactions and pathways involving p-xylene, (1,4-dimethylbenzene) a colorless, liquid aromatic hydrocarbon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903910", "l": "negative regulation of receptor clustering", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of receptor clustering."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046104", "l": "thymidine metabolic process", "d": ["The chemical reactions and pathways involving thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0033371", "l": "T cell secretory granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:0009712", "l": "catechol-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902008", "l": "negative regulation of toxin transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of toxin transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.871876592857262", "identifiers": [{"i": "GO:0005977", "l": "glycogen metabolic process", "d": ["The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0035743", "l": "CD4-positive, alpha-beta T cell cytokine production", "d": ["Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070094", "l": "positive regulation of glucagon secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0016553", "l": "base conversion or substitution editing", "d": ["Any base modification or substitution events that result in alterations in the coding potential or structural properties of RNAs as a result of changes in the base-pairing properties of the modified ribonucleoside(s)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032376", "l": "positive regulation of cholesterol transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080037", "l": "negative regulation of cytokinin-activated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cytokinin signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0006356", "l": "regulation of transcription by RNA polymerase I", "d": ["Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003169", "l": "coronary vein morphogenesis", "d": ["The process in which the anatomical structures of veins of the heart are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0072574", "l": "hepatocyte proliferation", "d": ["The multiplication or reproduction of hepatocytes, resulting in the expansion of a cell population. Hepatocytes form the main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019458", "l": "methionine catabolic process via 2-oxobutanoate", "d": ["The chemical reactions and pathways resulting in the breakdown of methionine, via the intermediate 2-oxobutanoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140125", "l": "thiamine import across plasma membrane", "d": ["The directed movement of thiamine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0007405", "l": "neuroblast proliferation", "d": ["The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900347", "l": "positive regulation of methane biosynthetic process from methanethiol", "d": ["Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methanethiol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0016061", "l": "regulation of light-activated channel activity", "d": ["Any process that modulates the frequency, rate or extent of light-activated channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0007391", "l": "dorsal closure", "d": ["The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0034112", "l": "positive regulation of homotypic cell-cell adhesion", "d": ["Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0048524", "l": "positive regulation of viral process", "d": ["Any process that activates or increases the frequency, rate or extent of a multi-organism process in which a virus is a participant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061940", "l": "regulation of c-di-GMP signaling", "d": ["Any process that modulates the rate frequency or extent of c-di-GMP signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071694", "l": "maintenance of protein location in extracellular region", "d": ["Any process in which a protein is maintained in a specific location within the extracellular region and is prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.687936058975897", "identifiers": [{"i": "GO:0009059", "l": "macromolecule biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015703", "l": "chromate transport", "d": ["The directed movement of chromate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.134834654920184", "identifiers": [{"i": "GO:0043066", "l": "negative regulation of apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046389", "l": "deoxyribose 5-phosphate metabolic process", "d": ["The chemical reactions and pathways involving deoxyribose 5-phosphate, the phosphorylated sugar 5-phospho-2-deoxyribose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0061004", "l": "pattern specification involved in kidney development", "d": ["Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000909", "l": "regulation of sterol import", "d": ["Any process that modulates the frequency, rate or extent of sterol import."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072664", "l": "maintenance of protein location in peroxisome", "d": ["Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0014896", "l": "muscle hypertrophy", "d": ["The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043685", "l": "conversion of glutamyl-tRNA to glutaminyl-tRNA", "d": ["The modification process that results in the conversion of glutamate charged on a tRNA(Gln) to glutaminyl-tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034409", "l": "ascospore wall (1->3)-beta-D-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0006829", "l": "zinc ion transport", "d": ["The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0043248", "l": "proteasome assembly", "d": ["The aggregation, arrangement and bonding together of a mature, active proteasome complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905889", "l": "positive regulation of cellular response to very-low-density lipoprotein particle stimulus", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071809", "l": "regulation of fever generation by regulation of prostaglandin biosynthesis", "d": ["Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903091", "l": "pyridoxamine transmembrane transport", "d": ["The process in which pyridoxamine is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046773", "l": "suppression by virus of host translation termination", "d": ["Any viral process that stops, prevents, or reduces the frequency, rate or extent of translational termination of a host mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001137", "l": "positive regulation of endocytic recycling", "d": ["Any process that activates or increases the frequency, rate or extent of endocytic recycling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.710614938732988", "identifiers": [{"i": "GO:0000278", "l": "mitotic cell cycle", "d": ["Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045232", "l": "S-layer organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an S-layer enveloping the cell. The S-layer is a crystalline protein layer surrounding some bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000804", "l": "regulation of termination of RNA polymerase II transcription, poly(A)-coupled", "d": ["Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071580", "l": "regulation of zinc ion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904803", "l": "regulation of translation involved in cellular response to UV", "d": ["Any regulation of translation that is involved in cellular response to UV."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002932", "l": "tendon sheath development", "d": ["The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0051274", "l": "beta-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-glucans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060112", "l": "generation of ovulation cycle rhythm", "d": ["The process which controls the timing of the type of sexual cycle seen in female mammals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098709", "l": "glutathione import across plasma membrane", "d": ["The directed movement of glutathione from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0006879", "l": "intracellular iron ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of iron ions within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045793", "l": "positive regulation of cell size", "d": ["Any process that increases cell size."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051105", "l": "regulation of DNA ligation", "d": ["Any process that modulates the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060222", "l": "regulation of retinal cone cell fate commitment", "d": ["Any process that modulates the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "44.668876055578323", "identifiers": [{"i": "GO:0006725", "l": "cellular aromatic compound metabolic process", "d": ["The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060680", "l": "lateral sprouting involved in ureteric bud morphogenesis", "d": ["The process in which a branch forms along the side of a ureteric bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.116918913335823", "identifiers": [{"i": "GO:0009123", "l": "nucleoside monophosphate metabolic process", "d": ["The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060020", "l": "Bergmann glial cell differentiation", "d": ["The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048383", "l": "mesectoderm development", "d": ["The process whose specific outcome is the progression of the mesectoderm over time, from its formation to the mature structure. In animal embryos, mesectoderm development processes give rise to both mesoderm and ectoderm tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046058", "l": "cAMP metabolic process", "d": ["The chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032710", "l": "negative regulation of interleukin-26 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-26 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001260", "l": "regulation of semaphorin-plexin signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of semaphorin-plexin signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0051298", "l": "centrosome duplication", "d": ["The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070487", "l": "monocyte aggregation", "d": ["The adhesion of one monocyte to one or more other monocytes via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990049", "l": "retrograde neuronal dense core vesicle transport", "d": ["The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0070595", "l": "(1->3)-alpha-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.281967957033203", "identifiers": [{"i": "GO:0002562", "l": "somatic diversification of immune receptors via germline recombination within a single locus", "d": ["The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046140", "l": "corrin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900862", "l": "negative regulation of cordyol C biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cordyol C biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0031168", "l": "ferrichrome metabolic process", "d": ["The chemical reactions and pathways involving a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060605", "l": "tube lumen cavitation", "d": ["The formation of a lumen by hollowing out a solid rod or cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0010561", "l": "negative regulation of glycoprotein biosynthetic process", "d": ["Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018233", "l": "peptide cross-linking via 2'-(S-L-cysteinyl)-L-histidine", "d": ["The modification of peptidyl-histidine and peptidyl-cysteine to form a 2'-(S-L-cysteinyl)-L-histidine protein cross-link."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902838", "l": "regulation of nuclear migration along microtubule", "d": ["Any process that modulates the frequency, rate or extent of nuclear migration along microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010915", "l": "regulation of very-low-density lipoprotein particle clearance", "d": ["Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001249", "l": "negative regulation of ammonia assimilation cycle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ammonia assimilation cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.598265520774746", "identifiers": [{"i": "GO:0002440", "l": "production of molecular mediator of immune response", "d": ["The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0006567", "l": "threonine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021964", "l": "rubrospinal tract morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900594", "l": "(+)-kotanin metabolic process", "d": ["The chemical reactions and pathways involving (+)-kotanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0048644", "l": "muscle organ morphogenesis", "d": ["The process in which the anatomical structures of muscle are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060800", "l": "regulation of cell differentiation involved in embryonic placenta development", "d": ["Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002342", "l": "central B cell deletion", "d": ["The deletion of B cells by apoptotic process occurring as part of central tolerance induction and B cell selection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090550", "l": "response to molybdenum starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of molybdenum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033516", "l": "L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine", "d": ["The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-phospho-L-homoserine and cystathionine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021765", "l": "cingulate gyrus development", "d": ["The progression of the cingulate gyrus over time from its initial formation until its mature state. The cingulate gyrus is a ridge in the cerebral cortex located dorsal to the corpus callosum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120137", "l": "positive regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity", "d": ["Any process that activates or increases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009958", "l": "positive gravitropism", "d": ["The orientation of plant parts towards gravity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097188", "l": "dentin mineralization", "d": ["The process in which calcium salts are deposited into the calcareous tooth structure known as dentin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.240853996207278", "identifiers": [{"i": "GO:0090150", "l": "establishment of protein localization to membrane", "d": ["The directed movement of a protein to a specific location in a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0035886", "l": "vascular associated smooth muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.003741351937961", "identifiers": [{"i": "GO:0014821", "l": "phasic smooth muscle contraction", "d": ["A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000481", "l": "positive regulation of cAMP-dependent protein kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of cAMP-dependent protein kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0060443", "l": "mammary gland morphogenesis", "d": ["The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1901800", "l": "positive regulation of proteasomal protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of proteasomal protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0010894", "l": "negative regulation of steroid biosynthetic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000723", "l": "negative regulation of cardiac vascular smooth muscle cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0046034", "l": "ATP metabolic process", "d": ["The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.619736723504786", "identifiers": [{"i": "GO:0034641", "l": "cellular nitrogen compound metabolic process", "d": ["The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036246", "l": "phytochelatin 2 import into vacuole", "d": ["The directed movement of phytochelatin 2 (PC2) into the vacuole. Phytochelatin 2 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=2, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901765", "l": "phosphinothricin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphinothricin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071264", "l": "positive regulation of translational initiation in response to starvation", "d": ["Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0052032", "l": "modulation by symbiont of host inflammatory response", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003105", "l": "negative regulation of glomerular filtration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032599", "l": "protein transport out of membrane raft", "d": ["The directed movement of a protein out of a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0006289", "l": "nucleotide-excision repair", "d": ["A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051151", "l": "negative regulation of smooth muscle cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061320", "l": "pericardial nephrocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0050779", "l": "RNA destabilization", "d": ["Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009717", "l": "isoflavonoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071386", "l": "cellular response to corticosterone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072142", "l": "juxtaglomerulus cell development", "d": ["The process whose specific outcome is the progression of a juxtaglomerulus cell over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0099098", "l": "microtubule polymerization based movement", "d": ["The movement of a cellular component as a result of microtubule polymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042849", "l": "L-sorbose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071801", "l": "regulation of podosome assembly", "d": ["Any process that modulates the frequency, rate or extent of podosome assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904435", "l": "regulation of transferrin receptor binding", "d": ["Any process that modulates the frequency, rate or extent of transferrin receptor binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048050", "l": "post-embryonic eye morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the eye are generated and organized. The eye is the organ of sight."]}]}
{"type": "biolink:BiologicalProcess", "ic": "48.771361792473513", "identifiers": [{"i": "GO:0048583", "l": "regulation of response to stimulus", "d": ["Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.194380709408335", "identifiers": [{"i": "GO:0007605", "l": "sensory perception of sound", "d": ["The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0060677", "l": "ureteric bud elongation", "d": ["The developmental growth in which the ureteric bud grows along its axis beginning with the growth of the primary ureteric bud and ending when the branches of the bud have elongated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043286", "l": "regulation of poly(3-hydroxyalkanoate) biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900335", "l": "positive regulation of methane biosynthetic process from 3-(methylthio)propionic acid", "d": ["Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000472", "l": "endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage between the 5'-External Transcribed Spacer (5'-ETS) and the 5' end of the SSU-rRNA of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001769", "l": "establishment of B cell polarity", "d": ["The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0031671", "l": "primary cell septum biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a primary cell septum following nuclear division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019489", "l": "methylgallate metabolic process", "d": ["The chemical reactions and pathways involving methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150091", "l": "multiple spine synapse organization, multiple dendrites", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and two or more dendritic spines protruding either from a single dendrite or from multiple dendrites."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075035", "l": "appressorium maturation", "d": ["The process in which specialized features of the symbiont appressorium are acquired post initiation, to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902202", "l": "regulation of hepatocyte growth factor receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0062100", "l": "positive regulation of programmed necrotic cell death", "d": ["Any process that increases the frequency, rate or extent of programmed necrotic cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080058", "l": "protein deglutathionylation", "d": ["The protein modification process in which a glutathione molecule is removed from a protein amino acid by breaking a disulfide linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034439", "l": "lipoprotein lipid oxidation", "d": ["The modification of a lipoprotein by oxidation of the lipid group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090615", "l": "mitochondrial mRNA processing", "d": ["Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.98780181426379", "identifiers": [{"i": "GO:1901654", "l": "response to ketone", "d": ["A response that results in a state of tolerance to ketone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060955", "l": "neural crest-derived cardiac glial cell fate commitment", "d": ["The commitment of neural crest cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.003741351937961", "identifiers": [{"i": "GO:0002886", "l": "regulation of myeloid leukocyte mediated immunity", "d": ["Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075281", "l": "positive regulation of uredinium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031407", "l": "oxylipin metabolic process", "d": ["The chemical reactions and pathways involving any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060176", "l": "regulation of aggregation involved in sorocarp development", "d": ["Any process that modulates the frequency, rate or extent of aggregation during sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901245", "l": "positive regulation of toll-like receptor 9 signaling pathway by B cell receptor internalization", "d": ["The movement of a B cell receptor (BCR) from the plasma membrane to the inside of the cell, which results in positive regulation of toll-like receptor 9 (TLR9) signaling. For example, internalized BCR signals to recruit TLR9 from multiple small endosomes to large autophagosome-like compartments to enhance TLR9 signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075227", "l": "regulation of encysted zoospore germination", "d": ["Any process that modulates the frequency, rate or extent of an encysted zoospore germination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902610", "l": "response to N-phenylthiourea", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034380", "l": "high-density lipoprotein particle assembly", "d": ["The non-covalent aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903790", "l": "guanine nucleotide transmembrane transport", "d": ["The process in which a guanyl nucleotide is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060990", "l": "lipid tube assembly involved in organelle fission", "d": ["The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles undergo fission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044065", "l": "regulation of respiratory system process", "d": ["Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046708", "l": "IDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of IDP, inosine 5'-diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0002713", "l": "negative regulation of B cell mediated immunity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0099072", "l": "regulation of postsynaptic membrane neurotransmitter receptor levels", "d": ["Any process that regulates the the local concentration of neurotransmitter receptor at the postsynaptic membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032751", "l": "positive regulation of interleukin-27 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-27 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071650", "l": "negative regulation of chemokine (C-C motif) ligand 5 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021894", "l": "cerebral cortex GABAergic interneuron development", "d": ["The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0046949", "l": "fatty-acyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090660", "l": "cerebrospinal fluid circulation", "d": ["The neurological system process driven by motile cilia on ependymal cells of the brain by which cerebrospinal fluid circulates from the sites of secretion to the sites of absorption. In ventricular cavities, the flow is unidirectional and rostrocaudal, in subarachnoid spaces, the flow is multi-directional."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106296", "l": "D-series resolvin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of resolvin family D-series, hydroxy fatty acids derived from docosahexaenoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0019388", "l": "galactose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019583", "l": "galactonate metabolic process", "d": ["The chemical reactions and pathways involving galactonate, the anion of galactonic acid, an organic acid derived from the sugar galactose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021771", "l": "lateral geniculate nucleus development", "d": ["The progression of the lateral geniculate nucleus over time from its initial formation until its mature state. The lateral geniculate nucleus is the primary processor of visual information received from the retina."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0015825", "l": "L-serine transport", "d": ["The directed movement of L-serine, the L-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905486", "l": "regulation of anterior/posterior axon guidance", "d": ["Any process that modulates the frequency, rate or extent of anterior/posterior axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140209", "l": "zinc ion import into endoplasmic reticulum", "d": ["The directed import of zinc(2+) from the cytosol, across the endoplasmic reticulum membrane, into the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034586", "l": "21U-RNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0098509", "l": "sensory perception of humidity", "d": ["The series of events required for an organism to detect some level of humidity in its environment, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070276", "l": "halogen metabolic process", "d": ["The chemical reactions and pathways involving any halogen, elements of Group VII; includes metabolism of halogen-containing compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031222", "l": "arabinan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of arabinan, a polysaccharide composed of arabinose residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120142", "l": "positive regulation of ecdysone receptor-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0071806", "l": "protein transmembrane transport", "d": ["The process in which a protein is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0009786", "l": "regulation of asymmetric cell division", "d": ["Any process that modulates the frequency, rate or extent of asymmetric cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048541", "l": "Peyer's patch development", "d": ["The process whose specific outcome is the progression of Peyer's patches over time, from their formation to the mature structure. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090514", "l": "L-tyrosine transmembrane import into vacuole", "d": ["The directed movement of L-tyrosine into the vacuole across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080128", "l": "anther septum development", "d": ["The process whose specific outcome is the progression of the anther septum over time, from its formation to the mature structure. The anther septum is a thin partition or stretch of cells that are present in the anther dehiscence zone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031637", "l": "regulation of neuronal synaptic plasticity in response to neurotrophin", "d": ["The process in which a neurotrophic factor induces neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901773", "l": "lincomycin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lincomycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0062229", "l": "regulation of larval somatic muscle development", "d": ["Any process that modulates the rate, frequency or extent of larval somatic muscle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071475", "l": "cellular hyperosmotic salinity response", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015957", "l": "bis(5'-nucleosidyl) oligophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098939", "l": "dendritic transport of mitochondrion", "d": ["The directed movement of mitochondria along microtubules in nerve cell dendrites."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990688", "l": "Golgi vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane", "d": ["The joining of the lipid bilayer membrane around a Golgi vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPI-coated transport vesicles involved in retrograde transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902818", "l": "ethyl acetate metabolic process", "d": ["The chemical reactions and pathways involving ethyl acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071872", "l": "cellular response to epinephrine stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007523", "l": "larval visceral muscle development", "d": ["The process whose specific outcome is the progression of the larval visceral muscle over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902112", "l": "cellular response to diethyl maleate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0006368", "l": "transcription elongation by RNA polymerase II", "d": ["The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010380", "l": "regulation of chlorophyll biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044727", "l": "epigenetic programing of male pronucleus", "d": ["The global programming of epigenetic modifications in the male pronucleus of the newly fertilized zygote. The most major change in the paternal genome is DNA demethylation, which takes place before the first cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0030174", "l": "regulation of DNA-templated DNA replication initiation", "d": ["Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904186", "l": "post-anaphase microtubule array organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly ofa post-anaphase microtubule array."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0045881", "l": "positive regulation of sporulation resulting in formation of a cellular spore", "d": ["Any process that activates or increases the frequency, rate or extent of sporulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903903", "l": "regulation of establishment of T cell polarity", "d": ["Any process that modulates the frequency, rate or extent of establishment of T cell polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098967", "l": "exocytic insertion of neurotransmitter receptor to postsynaptic membrane", "d": ["The exocytic fusion of neurotransmitter receptor containing vesicles with the postsynaptic membrane resulting in the integration of NT receptors, enabling them to participate in neurotransmitter reception. This process includes tethering and docking steps that prepare vesicles for fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030847", "l": "termination of RNA polymerase II transcription, exosome-dependent", "d": ["The process in which transcription of nonpolyadenylated RNA polymerase II transcripts is terminated; coupled to the maturation of the RNA 3'-end."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.071082486141265", "identifiers": [{"i": "GO:0032535", "l": "regulation of cellular component size", "d": ["A process that modulates the size of a cellular component."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030536", "l": "larval feeding behavior", "d": ["Feeding behavior in a larval (immature) organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0036265", "l": "RNA (guanine-N7)-methylation", "d": ["The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an RNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0005999", "l": "xylulose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of xylulose, the ketopentose threo-2-pentulose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0086069", "l": "bundle of His cell to Purkinje myocyte communication", "d": ["The process that mediates interactions between a bundle of His cell and its surroundings that contributes to the process of the bundle of His cell communicating with a Purkinje myocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072058", "l": "outer stripe development", "d": ["The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0050978", "l": "magnetoreception by sensory perception of electrical stimulus", "d": ["The series of events required for an organism to receive an electrical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Movement in a magnetic field results in an induced electric field, which can be perceived by organisms such as elasmobranch fish."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071483", "l": "cellular response to blue light", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033084", "l": "regulation of immature T cell proliferation in thymus", "d": ["Any process that modulates the frequency, rate or extent of immature T cell proliferation in the thymus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048361", "l": "root epithelial mucilage metabolic process", "d": ["The chemical reactions and pathways involving mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021530", "l": "spinal cord oligodendrocyte cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046418", "l": "nopaline metabolic process", "d": ["The chemical reactions and pathways involving nopaline, (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060257", "l": "negative regulation of flocculation", "d": ["Any process that decreases the rate, frequency or extent of the non-sexual aggregation of single-celled organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048482", "l": "plant ovule morphogenesis", "d": ["The process in which the anatomical structures of the ovule are generated and organized. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035396", "l": "positive regulation of chemokine (C-X-C motif) ligand 9 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051369", "l": "peptidyl-threonine decanoylation", "d": ["The decanoylation of peptidyl-threonine to form peptidyl-O3-decanoyl-L-threonine, typical of the protein ghrelin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0032490", "l": "detection of molecule of bacterial origin", "d": ["The series of events in which a stimulus from a molecule of bacterial origin is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900964", "l": "positive regulation of methanophenazine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of methanophenazine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900593", "l": "violaceol II biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of violaceol II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002003", "l": "angiotensin maturation", "d": ["The process leading to the attainment of the full functional capacity of angiotensin by conversion of angiotensinogen into mature angiotensin in the blood."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.651613913496419", "identifiers": [{"i": "GO:0001934", "l": "positive regulation of protein phosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051971", "l": "positive regulation of transmission of nerve impulse", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0051956", "l": "negative regulation of amino acid transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120061", "l": "negative regulation of gastric emptying", "d": ["Any process that decreases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0031396", "l": "regulation of protein ubiquitination", "d": ["Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0033002", "l": "muscle cell proliferation", "d": ["The expansion of a muscle cell population by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080141", "l": "regulation of jasmonic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of jasmonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071349", "l": "cellular response to interleukin-12", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160031", "l": "endoplasmic reticulum membrane biogenesis", "d": ["The process in which an endoplasmic reticulum membrane is synthesized, aggregates, and bonds together."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060133", "l": "somatotropin secreting cell development", "d": ["The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905881", "l": "positive regulation of oogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of oogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0010410", "l": "hemicellulose metabolic process", "d": ["The chemical reactions and pathways involving hemicelluloses, plant cell wall polysaccharides that have a backbone of 1,4-linked beta-D-pyranosyl residues in which O4 is in the equatorial orientation. Many different hemicelluloses usually occur intermixed with each molecular type representing different degrees of polymerization and contain many different sugar monomers, which can include glucose, xylose, mannose, galactose, and arabinose. Hemicelluloses also contain most of the D-pentose sugars and occasionally small amounts of L-sugars as well. Xylose is always the sugar monomer present in the largest amount, but mannuronic acid and galacturonic acid also tend to be present."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035815", "l": "positive regulation of renal sodium excretion", "d": ["Any process that increases the amount of sodium excreted in urine over a unit of time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033606", "l": "chemokine receptor transport within lipid bilayer", "d": ["The directed movement of a chemokine receptor within a lipid bilayer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.062480095235458", "identifiers": [{"i": "GO:0045055", "l": "regulated exocytosis", "d": ["A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070681", "l": "glutaminyl-tRNAGln biosynthesis via transamidation", "d": ["A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061092", "l": "positive regulation of phospholipid translocation", "d": ["Any process that increases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000733", "l": "regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation", "d": ["Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003277", "l": "apoptotic process involved in endocardial cushion morphogenesis", "d": ["Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.642927237245431", "identifiers": [{"i": "GO:0009112", "l": "nucleobase metabolic process", "d": ["The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0014042", "l": "positive regulation of neuron maturation", "d": ["Any process that activates or increases the frequency, rate or extent of neuron maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019669", "l": "anaerobic glycine catabolic process", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glycine, yielding energy in the form of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097335", "l": "response to quetiapine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quetiapine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001777", "l": "T cell homeostatic proliferation", "d": ["The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0018427", "l": "copper incorporation into metallo-sulfur cluster", "d": ["The incorporation of copper into a metallo-sulfur cluster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901339", "l": "regulation of store-operated calcium channel activity", "d": ["Any process that modulates the frequency, rate or extent of store-operated calcium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0019320", "l": "hexose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080034", "l": "host response to induction by symbiont of tumor, nodule or growth in host", "d": ["Any process that results in a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the formation of an abnormal mass of cells in the host organism, induced by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033616", "l": "plasma membrane proton-transporting ATP synthase complex assembly", "d": ["The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018412", "l": "protein O-glucuronidation", "d": ["The modification of a protein by glucuronidation on an amino acid oxygen atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.465174152298118", "identifiers": [{"i": "GO:0072384", "l": "organelle transport along microtubule", "d": ["The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:0032107", "l": "regulation of response to nutrient levels", "d": ["Any process that modulates the frequency, rate or extent of a response to nutrient levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.62986809207635", "identifiers": [{"i": "GO:0061061", "l": "muscle structure development", "d": ["The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0031111", "l": "negative regulation of microtubule polymerization or depolymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.644186068201407", "identifiers": [{"i": "GO:0002064", "l": "epithelial cell development", "d": ["The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060453", "l": "regulation of gastric acid secretion", "d": ["Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0002423", "l": "natural killer cell mediated immune response to tumor cell", "d": ["An immune response mediated by a natural killer cell triggered in response to the presence of a tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071072", "l": "negative regulation of phospholipid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0097212", "l": "lysosomal membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.825956045430587", "identifiers": [{"i": "GO:0032506", "l": "cytokinetic process", "d": ["A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019342", "l": "trypanothione biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of trypanothione (N1,N6,-bis(glutathionyl)spermidine) in two steps from glutathione and spermidine via an N1- or N8-glutathionylspermidine intermediate. Trypanothione appears to be an essential redox intermediate in intracellular thiol redox regulation. It also plays a role in protecting against oxidative stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035291", "l": "specification of segmental identity, intercalary segment", "d": ["The specification of the characteristic structures of the intercalary segment of the anterior head, following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0040036", "l": "regulation of fibroblast growth factor receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901030", "l": "positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.909905611858392", "identifiers": [{"i": "GO:0055123", "l": "digestive system development", "d": ["The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009557", "l": "antipodal cell differentiation", "d": ["The process in which an uncellularized nucleus cellularizes and acquires the specialized features of an antipodal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097375", "l": "spinal sensory neuron axon guidance", "d": ["The process in which the migration of an axon growth cone of a spinal sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal sensory neuron is a sensory neuron that project to the spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.824318789188837", "identifiers": [{"i": "GO:0070192", "l": "chromosome organization involved in meiotic cell cycle", "d": ["A process of chromosome organization that is involved in a meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072019", "l": "proximal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the proximal convoluted tubule over time, from its formation to the mature structure. The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.796765247784244", "identifiers": [{"i": "GO:0030001", "l": "metal ion transport", "d": ["The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046882", "l": "negative regulation of follicle-stimulating hormone secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090119", "l": "vesicle-mediated cholesterol transport", "d": ["The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, by membrane-bounded vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901083", "l": "pyrrolizidine alkaloid metabolic process", "d": ["The chemical reactions and pathways involving pyrrolizidine alkaloid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0070199", "l": "establishment of protein localization to chromosome", "d": ["The directed movement of a protein to a specific location on a chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140528", "l": "bilobe structure assembly", "d": ["The assembly and organization of a bilobe structure, a cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044807", "l": "macrophage migration inhibitory factor production", "d": ["The appearance of macrophage migration inhibitory factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:1902932", "l": "positive regulation of alcohol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of alcohol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097700", "l": "vascular endothelial cell response to laminar fluid shear stress", "d": ["Any response to laminar fluid shear stress in a vascular endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.358732272612386", "identifiers": [{"i": "GO:0021953", "l": "central nervous system neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019817", "l": "vesicle fusion with peroxisome", "d": ["The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the peroxisome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.938643630768524", "identifiers": [{"i": "GO:0043269", "l": "regulation of monoatomic ion transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042452", "l": "deoxyguanosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006671", "l": "phytosphingosine metabolic process", "d": ["The chemical reactions and pathways involving phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol, a constituent of many plant sphingolipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990052", "l": "ER to chloroplast lipid transport", "d": ["The directed movement of a lipid from the endoplasmic reticulum (ER) to the chloroplast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0030832", "l": "regulation of actin filament length", "d": ["Any process that controls the length of actin filaments in a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070373", "l": "negative regulation of ERK1 and ERK2 cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003196", "l": "ventriculo bulbo valve formation", "d": ["The developmental process pertaining to the initial formation of the ventriculo bulbo valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090076", "l": "relaxation of skeletal muscle", "d": ["A process in which the extent of skeletal muscle tissue contraction is reduced. Muscle relaxation involves the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "45.829218008043647", "identifiers": [{"i": "GO:0048518", "l": "positive regulation of biological process", "d": ["Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000381", "l": "negative regulation of mesoderm development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0045920", "l": "negative regulation of exocytosis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071379", "l": "cellular response to prostaglandin stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903968", "l": "cellular response to micafungin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0072215", "l": "regulation of metanephros development", "d": ["Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0070841", "l": "inclusion body assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an inclusion body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "48.645521309001559", "identifiers": [{"i": "GO:0099643", "l": "signal release from synapse", "d": ["Any signal release from a synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0071616", "l": "acyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030714", "l": "anterior/posterior axis specification, follicular epithelium", "d": ["Polarization of the follicle cells of an insect ovary along the anterior/posterior axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045904", "l": "negative regulation of translational termination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0141008", "l": "retrotransposon silencing by mRNA destabilization", "d": ["A retrotransposon silencing mechanism in which mRNAs transcribed from transposons are targeted for degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901733", "l": "quercetin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of quercetin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071473", "l": "cellular response to cation stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097293", "l": "XMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900092", "l": "negative regulation of raffinose biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of raffinose biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045693", "l": "positive regulation of embryo sac central cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of embryo sac central cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0090487", "l": "secondary metabolite catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090427", "l": "activation of meiosis", "d": ["Any process that starts the inactive process of meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042496", "l": "detection of diacyl bacterial lipopeptide", "d": ["The series of events in which a diacylated bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal. Diacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of two acyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1901335", "l": "lactone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lactone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.622337805354121", "identifiers": [{"i": "GO:0042440", "l": "pigment metabolic process", "d": ["The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902055", "l": "positive regulation of neosartoricin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of neosartoricin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0030299", "l": "intestinal cholesterol absorption", "d": ["Uptake of cholesterol into the blood by absorption from the small intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019250", "l": "aerobic cobalamin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the presence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002737", "l": "negative regulation of plasmacytoid dendritic cell cytokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032720", "l": "negative regulation of tumor necrosis factor production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019499", "l": "cyanide metabolic process", "d": ["The chemical reactions and pathways involving cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration, reacting with the ferric form of cytochrome aa3 and thus blocking the electron transport chain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0016480", "l": "negative regulation of transcription by RNA polymerase III", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase III."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070723", "l": "response to cholesterol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032918", "l": "spermidine acetylation", "d": ["The modification of spermidine by addition of acetyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905680", "l": "regulation of innate immunity memory response", "d": ["Any process that modulates the frequency, rate or extent of innate immunity memory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.656143477476277", "identifiers": [{"i": "GO:0006355", "l": "regulation of DNA-templated transcription", "d": ["Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0020033", "l": "antigenic variation", "d": ["Any process involved in the biological strategy of changing antigenic determinants on the surface that are exposed to another organism's immune system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0006891", "l": "intra-Golgi vesicle-mediated transport", "d": ["The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019550", "l": "glutamate catabolic process to aspartate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including aspartate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033493", "l": "esculetin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of esculetin, 6,7-dihydroxycoumarin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0090480", "l": "purine nucleotide-sugar transmembrane transport", "d": ["The process in which a purine nucleotide-sugar is transported across a membrane. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002281", "l": "macrophage activation involved in immune response", "d": ["A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006211", "l": "5-methylcytosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 5-methylcytosine, a methylated base of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097155", "l": "fasciculation of sensory neuron axon", "d": ["The collection of sensory neuron axons into a bundle of rods, known as a fascicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009449", "l": "gamma-aminobutyric acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032436", "l": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0140456", "l": "initial meiotic spindle pole body separation", "d": ["The release of duplicated meiotic spindle pole bodies (SPBs)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.432445482536949", "identifiers": [{"i": "GO:0001558", "l": "regulation of cell growth", "d": ["Any process that modulates the frequency, rate, extent or direction of cell growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002789", "l": "negative regulation of antifungal peptide production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046647", "l": "negative regulation of gamma-delta T cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0006696", "l": "ergosterol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032333", "l": "activin secretion", "d": ["The regulated release of activin, a nonsteroidal regulator composed of two covalently linked beta subunits, which is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098002", "l": "receptor-mediated bacteriophage irreversible attachment to host cell", "d": ["The processes by which a bacteriophage initially commits to infection by binding the host receptor irreversibly. Disruption of the phage:cell complex at this step results in the loss of infective phage virions since the process is characterized by conformational changes of bacteriophage head and tail proteins and injection of bacteriophage proteins into the infected cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052700", "l": "ergothioneine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035627", "l": "ceramide transport", "d": ["The directed movement of ceramides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903250", "l": "positive regulation of citrulline biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of citrulline biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035432", "l": "positive regulation of gluconate transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:2000765", "l": "regulation of cytoplasmic translation", "d": ["Any process that modulates the frequency, rate or extent of cytoplasmic translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905648", "l": "regulation of shell calcification", "d": ["Any process that modulates the frequency, rate or extent of shell calcification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050783", "l": "cocaine metabolic process", "d": ["The chemical reactions and pathways involving cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072470", "l": "response to cell size control checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of cell size control checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990456", "l": "mitochondrion-endoplasmic reticulum membrane tethering", "d": ["The attachment of a mitochondrion and an endoplasmic reticulum via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0010395", "l": "rhamnogalacturonan I metabolic process", "d": ["The chemical reactions and pathways involving rhamnogalacturonan I (RGI), a branched pectin with a backbone of alternating alpha-(1->2)-linked rhamnose and alpha-(1->4)-linked D-galacturonic acid residues that carries neutral side-chains of predominantly beta-(1->4)-D-galactose and/or alpha-(1->5)-L-arabinose residues attached to the rhamnose residues of the RGI backbone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901510", "l": "(-)-microperfuranone metabolic process", "d": ["The chemical reactions and pathways involving (-)-microperfuranone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:2000045", "l": "regulation of G1/S transition of mitotic cell cycle", "d": ["Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901056", "l": "trimethylenediamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of trimethylenediamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019317", "l": "fucose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fucose (6-deoxygalactose)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0110012", "l": "protein localization to P-body", "d": ["Any process in which a protein is transported to, or maintained at, a P-body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900112", "l": "regulation of histone H3-K9 trimethylation", "d": ["Any process that modulates the frequency, rate or extent of histone H3-K9 trimethylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097088", "l": "interleukin-17F production", "d": ["The appearance of interleukin-17F due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0043542", "l": "endothelial cell migration", "d": ["The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010606", "l": "positive regulation of cytoplasmic mRNA processing body assembly", "d": ["Any process that increases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901647", "l": "positive regulation of synoviocyte proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of synoviocyte proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046783", "l": "modification by virus of host polysomes", "d": ["Any viral process that interferes with and inhibits the assembly and function of polysomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.789865030533292", "identifiers": [{"i": "GO:0051240", "l": "positive regulation of multicellular organismal process", "d": ["Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098914", "l": "membrane repolarization during atrial cardiac muscle cell action potential", "d": ["The process in which ions are transported across a membrane such that the atrial cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904985", "l": "negative regulation of quinolinate biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of quinolinate biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0006600", "l": "creatine metabolic process", "d": ["The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0003321", "l": "positive regulation of blood pressure by epinephrine-norepinephrine", "d": ["Any process in which the force of blood traveling through the circulatory system is increased by the chemicals epinephrine and norepinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002358", "l": "B cell homeostatic proliferation", "d": ["The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0009933", "l": "meristem structural organization", "d": ["Organization of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035989", "l": "tendon development", "d": ["The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035395", "l": "negative regulation of chemokine (C-X-C motif) ligand 9 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071109", "l": "superior temporal gyrus development", "d": ["The process whose specific outcome is the progression of the superior temporal gyrus over time, from its formation to the mature structure. The superior temporal gyrus is a portion of the cerebral cortex that extends from the lateral sulcus to the superior temporal sulcus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002338", "l": "B-1b B cell differentiation", "d": ["The process in which B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061907", "l": "negative regulation of AMPA receptor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900063", "l": "regulation of peroxisome organization", "d": ["Any process that modulates the frequency, rate or extent of peroxisome organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032995", "l": "regulation of fungal-type cell wall biogenesis", "d": ["Any process that modulates the process in which a cell wall is synthesized, aggregates, and bonds together. The fungal-type cell wall contains beta-glucan and may contain chitin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061237", "l": "convergent extension involved in mesonephric nephron morphogenesis", "d": ["The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010470", "l": "regulation of gastrulation", "d": ["Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0089708", "l": "L-histidine transmembrane export from vacuole", "d": ["The directed movement of L-histidine out of the vacuole, across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009641", "l": "shade avoidance", "d": ["Shade avoidance is a set of responses that plants display when they are subjected to the shade of another plant. It often includes elongation, altered flowering time, increased apical dominance and altered partitioning of resources. Plants are able to distinguish between the shade of an inanimate object (e.g. a rock) and the shade of another plant due to the altered balance between red and far-red light in the shade of a plant; this balance between red and far-red light is perceived by phytochrome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140572", "l": "vacuole fission", "d": ["The division of a vacuole within a cell to form two or more separate vacuoles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0014733", "l": "regulation of skeletal muscle adaptation", "d": ["Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042543", "l": "protein N-linked glycosylation via arginine", "d": ["The glycosylation of protein via peptidyl-arginine, omega-N-glycosyl-L-arginine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097084", "l": "vascular associated smooth muscle cell development", "d": ["The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010626", "l": "negative regulation of Schwann cell proliferation", "d": ["Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033252", "l": "regulation of beta-lactamase activity", "d": ["Any process that modulates the frequency, rate or extent of beta-lactamase activity, the hydrolysis of a beta-lactam to yield a substituted beta-amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046273", "l": "lignan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120141", "l": "regulation of ecdysone receptor-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the activity of any ecdysone receptor-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022005", "l": "midbrain-hindbrain boundary maturation during neural plate development", "d": ["A developmental process occurring before the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034136", "l": "negative regulation of toll-like receptor 2 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 2 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900533", "l": "palmitic acid metabolic process", "d": ["The chemical reactions and pathways involving palmitic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007285", "l": "primary spermatocyte growth", "d": ["The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900695", "l": "regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010231", "l": "maintenance of seed dormancy", "d": ["Any process that maintains a seed in a dormant state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006062", "l": "sorbitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901424", "l": "response to toluene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toluene stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0098734", "l": "macromolecule depalmitoylation", "d": ["The removal of palymitoyl groups from a macromolecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015966", "l": "diadenosine tetraphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900696", "l": "negative regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061755", "l": "positive regulation of circulating fibrinogen levels", "d": ["Any process that increases the quantity of fibrinogen circulating in the bloodstream."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905064", "l": "negative regulation of vascular associated smooth muscle cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032532", "l": "regulation of microvillus length", "d": ["A process that modulates the length of a microvillus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140899", "l": "plastid gene expression", "d": ["The process in which a plastid gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033137", "l": "negative regulation of peptidyl-serine phosphorylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.724229354797117", "identifiers": [{"i": "GO:0006816", "l": "calcium ion transport", "d": ["The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904185", "l": "equatorial microtubule organizing center assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an equatorial microtubule organizing center."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002659", "l": "negative regulation of peripheral tolerance induction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0060561", "l": "apoptotic process involved in morphogenesis", "d": ["Any apoptotic process that contributes to the shaping of an anatomical structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0052805", "l": "imidazole-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0042148", "l": "strand invasion", "d": ["The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044515", "l": "envenomation resulting in positive regulation of glucagon-like peptide receptor 1 activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of glucagon-like peptide receptor 1 activity in of the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0016098", "l": "monoterpenoid metabolic process", "d": ["The chemical reactions and pathways involving monoterpenoid compounds, terpenoids having a C10 skeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015010", "l": "tetrahydrocorphin metabolic process", "d": ["The chemical reactions and pathways involving tetrahydrocorphins, tetrapyrroles that combine the structural elements of both porphyrins and corrins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903953", "l": "negative regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904665", "l": "positive regulation of N-terminal peptidyl-methionine acetylation", "d": ["Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-methionine acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015713", "l": "phosphoglycerate transmembrane transport", "d": ["The process in which phosphoglycerate is transported across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0001060", "l": "transcription by RNA polymerase V", "d": ["The synthesis of RNA from a DNA template by RNA polymerase V, originating at a Pol V-specific promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0044671", "l": "sorocarp spore cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a sorocarp spore cell, a cell of the sorocarp sorus. A sorocarp is the fruiting body characteristic of certain cellular slime moulds (e.g., Dictyosteliida) and consists of both stalk and a sorus (spore mass)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042003", "l": "masculinization of hermaphrodite soma", "d": ["Promotion of male sex and sexual phenotypes in the hermaphroditic nematode soma. An example of this is found in Caenorhabditis elegans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.675373588411375", "identifiers": [{"i": "GO:0034767", "l": "positive regulation of monoatomic ion transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.646237807976007", "identifiers": [{"i": "GO:0022412", "l": "cellular process involved in reproduction in multicellular organism", "d": ["A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051562", "l": "negative regulation of mitochondrial calcium ion concentration", "d": ["Any process that decreases the concentration of calcium ions in mitochondria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902947", "l": "regulation of tau-protein kinase activity", "d": ["Any process that modulates the frequency, rate or extent of tau-protein kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048652", "l": "polyphenic determination, influence by genetic factors", "d": ["The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to genetic cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034552", "l": "respiratory chain complex II assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001808", "l": "negative regulation of type IV hypersensitivity", "d": ["Any process that stops, prevents, or reduces the rate of type IV hypersensitivity, a type of inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903674", "l": "regulation of cap-dependent translational initiation", "d": ["Any process that modulates the frequency, rate or extent of cap-dependent translational initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140146", "l": "calcium ion import into vacuole", "d": ["The directed movement of calcium cations into the vacuole across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010500", "l": "transmitting tissue development", "d": ["The process whose specific outcome is the progression of the transmitting tract over time, from its formation to the mature structure. The transmitting tissue is the tissue in the style of a carpel through which the pollen tube grows; it connects the stigma and the inside of ovary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070859", "l": "positive regulation of bile acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009998", "l": "negative regulation of retinal cone cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from specifying into a retinal cone cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032048", "l": "cardiolipin metabolic process", "d": ["The chemical reactions and pathways involving cardiolipin, 1,3-bis(3-phosphatidyl)glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032494", "l": "response to peptidoglycan", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043163", "l": "cell envelope organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cell envelope, everything external to, but not including, the cytoplasmic membrane of bacteria, encompassing the periplasmic space, cell wall, and outer membrane if present."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0060445", "l": "branching involved in salivary gland morphogenesis", "d": ["The process in which the branching structure of the salivary gland is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0032380", "l": "regulation of intracellular sterol transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of sterols within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006149", "l": "deoxyinosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of deoxyinosine, hypoxanthine deoxyriboside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.295828638494967", "identifiers": [{"i": "GO:1901657", "l": "glycosyl compound metabolic process", "d": ["The chemical reactions and pathways involving glycosyl compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1904181", "l": "positive regulation of membrane depolarization", "d": ["Any process that activates or increases the frequency, rate or extent of membrane depolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905396", "l": "cellular response to flavonoid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007488", "l": "histoblast morphogenesis", "d": ["The process in which the anatomical structures derived from the histoblast disc are generated and organized. This includes the transformation of histoblast cells into adult structures during pupal metamorphosis. Histoblast cells are cells founded in the embryo that are the progenitors to the adult abdomen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000008", "l": "regulation of protein localization to cell surface", "d": ["Any process that modulates the frequency, rate or extent of protein localization to the cell surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900289", "l": "negative regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.741061915800707", "identifiers": [{"i": "GO:0051052", "l": "regulation of DNA metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048107", "l": "4-amino-3-isothiazolidinone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 4-amino-3-isothiazolinone, five-membered saturated heterocyclic ring structures containing a sulfur and a nitrogen in the 1-position and 2-positions respectively."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072258", "l": "metanephric interstitial fibroblast differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the metanephros as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0019662", "l": "non-glycolytic fermentation", "d": ["Fermentation that does not include the anaerobic conversion of glucose to pyruvate via the glycolytic pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905813", "l": "negative regulation of motor neuron axon guidance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.824513090543306", "identifiers": [{"i": "GO:0001942", "l": "hair follicle development", "d": ["The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903353", "l": "regulation of nucleus organization", "d": ["Any process that modulates the frequency, rate or extent of nucleus organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0055057", "l": "neuroblast division", "d": ["The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.033057138195133", "identifiers": [{"i": "GO:0032881", "l": "regulation of polysaccharide metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902392", "l": "regulation of exodeoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of exodeoxyribonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009635", "l": "response to herbicide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a herbicide stimulus. Herbicides are chemicals used to kill or control the growth of plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019639", "l": "6-hydroxycineole catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.523519163150823", "identifiers": [{"i": "GO:0009064", "l": "glutamine family amino acid metabolic process", "d": ["The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035865", "l": "cellular response to potassium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902526", "l": "negative regulation of protein monoubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein monoubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050950", "l": "positive regulation of late stripe melanocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of late stripe melanocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032749", "l": "positive regulation of interleukin-25 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-25 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048212", "l": "Golgi vesicle uncoating", "d": ["The process in which Golgi vesicle coat proteins are depolymerized, and released for reuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905520", "l": "positive regulation of presynaptic active zone assembly", "d": ["Any process that activates or increases the frequency, rate or extent of presynaptic active zone assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.636998499829652", "identifiers": [{"i": "GO:0006338", "l": "chromatin remodeling", "d": ["A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090593", "l": "peptidyl-histidine autophosphorylation", "d": ["The phosphorylation by a protein of one or more of its own histidine residues, or a histidine residue on an identical protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072286", "l": "metanephric connecting tubule development", "d": ["The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051943", "l": "positive regulation of amino acid uptake involved in synaptic transmission", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000348", "l": "regulation of CD40 signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of signaling via the CD40 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.481944844857608", "identifiers": [{"i": "GO:0051254", "l": "positive regulation of RNA metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0035834", "l": "indole alkaloid metabolic process", "d": ["The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000584", "l": "negative regulation of platelet-derived growth factor receptor-alpha signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901027", "l": "dextrin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dextrin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006718", "l": "juvenile hormone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034516", "l": "response to vitamin B6", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.585103934178449", "identifiers": [{"i": "GO:0048820", "l": "hair follicle maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901930", "l": "alpha-copaene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alpha-copaene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000877", "l": "negative regulation of oligopeptide transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021944", "l": "neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration", "d": ["The changes in adhesion between a neuronal cell and a glial cell as a component of the process of hindbrain glial-mediated radial cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061592", "l": "phosphatidylserine exposure on osteoblast involved in bone mineralization", "d": ["A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of osteoblasts, and contributes to bone mineralization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0070997", "l": "neuron death", "d": ["The process of cell death in a neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019746", "l": "hopanoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0006740", "l": "NADPH regeneration", "d": ["A metabolic process that generates a pool of NADPH by the reduction of NADP+."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048098", "l": "antennal joint development", "d": ["The process whose specific outcome is the progression of the antennal joint over time, from its formation to the mature structure. The antennal joint is the joint between antennal segments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.232064878529073", "identifiers": [{"i": "GO:0018212", "l": "peptidyl-tyrosine modification", "d": ["The modification of peptidyl-tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019295", "l": "coenzyme M biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000773", "l": "negative regulation of cellular senescence", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002906", "l": "negative regulation of mature B cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098884", "l": "postsynaptic neurotransmitter receptor internalization", "d": ["A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor from the postsynaptic membrane endocytic zone into an endocytic vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.062476272212777", "identifiers": [{"i": "GO:0016236", "l": "macroautophagy", "d": ["The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904398", "l": "positive regulation of neuromuscular junction development", "d": ["Any process that activates or increases the frequency, rate or extent of neuromuscular junction development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.08925528631891", "identifiers": [{"i": "GO:1901135", "l": "carbohydrate derivative metabolic process", "d": ["The chemical reactions and pathways involving carbohydrate derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0016259", "l": "selenocysteine metabolic process", "d": ["The chemical reactions and pathways involving selenocysteine, an essential component of glutathione peroxidase and some other proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035810", "l": "positive regulation of urine volume", "d": ["Any process that increases the amount of urine excreted from the body over a unit of time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048741", "l": "skeletal muscle fiber development", "d": ["The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000626", "l": "negative regulation of miRNA catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of miRNA catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0110033", "l": "regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway, the series of molecular signals generated as a consequence of glucose binding to a G protein-coupled receptor, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903696", "l": "protein localization to horsetail-astral microtubule array", "d": ["A process in which a protein is transported to, or maintained in, a location within a horsetail-astral microtubule array."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.572744119402742", "identifiers": [{"i": "GO:0048367", "l": "shoot system development", "d": ["The process whose specific outcome is the progression of the shoot system over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072177", "l": "mesonephric duct development", "d": ["The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900217", "l": "regulation of apoptotic process involved in metanephric nephron tubule development", "d": ["Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902731", "l": "negative regulation of chondrocyte proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002842", "l": "positive regulation of T cell mediated immune response to tumor cell", "d": ["Any process that activates or increases the frequency, rate, or extent of a T cell mediated immune response to tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033091", "l": "positive regulation of immature T cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of immature T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019508", "l": "2,5-dihydroxypyridine catabolic process to fumarate", "d": ["The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine to form fumarate. 2,5-dihydroxypyridine is dioxygenated to give maleamate and formate; the maleamate from this reaction is then converted to maleate, which is then isomerized to fumurate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044487", "l": "envenomation resulting in modulation of transmission of nerve impulse in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the transmission of nerve impulses in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061469", "l": "regulation of type B pancreatic cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.114054827751424", "identifiers": [{"i": "GO:0044248", "l": "cellular catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0043320", "l": "natural killer cell degranulation", "d": ["The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120311", "l": "ciliary pro-basal body maturation", "d": ["A process that is carried out at the cellular level which results in the conversion of an immature and partially assembled ciliary pro-basal body into a mature basal body that is capable of nucleating a cilium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900233", "l": "positive regulation of single-species biofilm formation on inanimate substrate", "d": ["Any process that activates or increases the frequency, rate or extent of single-species biofilm formation on inanimate substrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0032768", "l": "regulation of monooxygenase activity", "d": ["Any process that modulates the activity of a monooxygenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901471", "l": "positive regulation of syringal lignin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of syringal lignin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060493", "l": "mesenchymal-endodermal cell signaling involved in lung induction", "d": ["Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell in the foregut and contributes to the formation of the lung bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060471", "l": "cortical granule exocytosis", "d": ["The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060746", "l": "parental behavior", "d": ["A reproductive behavior in which a parent cares for and rears offspring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000946", "l": "negative regulation of amylopectin catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905831", "l": "negative regulation of spindle assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of spindle assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0031440", "l": "regulation of mRNA 3'-end processing", "d": ["Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046344", "l": "ecdysteroid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150141", "l": "negative regulation of CD86 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD86 biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019285", "l": "glycine betaine biosynthetic process from choline", "d": ["The chemical reactions and pathways resulting in the formation of betaine (N-trimethylglycine) from the oxidation of choline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0007465", "l": "R7 cell fate commitment", "d": ["The process in which the R7 photoreceptor commits to its cell fate. The R7 receptor contributes the central part of the rhabdomere in the apical parts of the ommatidium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902832", "l": "negative regulation of cell proliferation in dorsal spinal cord", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in dorsal spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902329", "l": "bacterial-type DNA replication termination", "d": ["Any DNA replication termination that is involved in bacterial-type DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008065", "l": "establishment of blood-nerve barrier", "d": ["The establishment of the barrier between the perineurium of peripheral nerves and the vascular endothelium of endoneurial capillaries. The perineurium acts as a diffusion barrier, but ion permeability at the blood-nerve barrier is still higher than at the blood-brain barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905691", "l": "lipid droplet disassembly", "d": ["The disaggregation of a lipid particle into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071403", "l": "cellular response to high density lipoprotein particle stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009787", "l": "regulation of abscisic acid-activated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of abscisic acid (ABA) signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046250", "l": "limonene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035875", "l": "maintenance of meiotic sister chromatid cohesion, centromeric", "d": ["The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900926", "l": "regulation of L-threonine import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of L-threonine import into cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045805", "l": "positive regulation of eclosion", "d": ["Any process that activates or increases the frequency, rate or extent of eclosion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0019541", "l": "propionate metabolic process", "d": ["The chemical reactions and pathways involving propionate, the anion derived from propionic (propanoic) acid, a carboxylic acid important in the energy metabolism of ruminants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904525", "l": "positive regulation of DNA amplification", "d": ["Any process that activates or increases the frequency, rate or extent of DNA amplification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001103", "l": "maltohexaose transport", "d": ["The directed movement of a maltohexaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.569439710577498", "identifiers": [{"i": "GO:0045005", "l": "DNA-templated DNA replication maintenance of fidelity", "d": ["A DNA metabolic process that prevents or corrects errors to ensure that DNA is replicated accurately. Errors can be corrected either by intrinsic DNA polymerase proofreading activity or via mismatch repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045781", "l": "negative regulation of cell budding", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell budding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0031629", "l": "synaptic vesicle fusion to presynaptic active zone membrane", "d": ["Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051543", "l": "regulation of elastin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030220", "l": "platelet formation", "d": ["The process in which platelets bud from long processes extended by megakaryocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002879", "l": "positive regulation of acute inflammatory response to non-antigenic stimulus", "d": ["Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0038083", "l": "peptidyl-tyrosine autophosphorylation", "d": ["The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosine residue on an identical protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071816", "l": "tail-anchored membrane protein insertion into ER membrane", "d": ["A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018362", "l": "peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester", "d": ["The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010512", "l": "negative regulation of phosphatidylinositol biosynthetic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1903795", "l": "regulation of inorganic anion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of inorganic anion transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000508", "l": "regulation of dendritic cell chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006258", "l": "UDP-glucose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033496", "l": "sinapate metabolic process", "d": ["The chemical reactions and pathways involving sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900976", "l": "positive regulation of tatiopterin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of tatiopterin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035633", "l": "maintenance of blood-brain barrier", "d": ["Maintaining the structure and function of the blood-brain barrier, thus ensuring specific regulated transport of substances (e.g. macromolecules, small molecules, ions) into the brain, and out of the brain into the blood circulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051332", "l": "meiotic S phase", "d": ["The cell cycle phase, following G1, during which DNA synthesis takes place as part of a meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021618", "l": "hypoglossal nerve morphogenesis", "d": ["The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "43.216723189618122", "identifiers": [{"i": "GO:0009605", "l": "response to external stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042915", "l": "group A colicin transport", "d": ["The directed movement of group A colicins (colicins E1, E2, E3, A, K, and N) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.031014075193482", "identifiers": [{"i": "GO:0048878", "l": "chemical homeostasis", "d": ["Any biological process involved in the maintenance of an internal steady state of a chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035928", "l": "rRNA import into mitochondrion", "d": ["The process in which a rRNA, ribosomal ribonucleic acid, transported from the cytosol into the mitochondrial matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0007076", "l": "mitotic chromosome condensation", "d": ["The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031101", "l": "fin regeneration", "d": ["The regrowth of fin tissue following its loss or destruction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140114", "l": "cellular detoxification of fluoride", "d": ["Any process carried out at the cellular level that reduces or removes the toxicity of a fluoride. These may include chemical modification or transport of fluoride away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905371", "l": "ceramide phosphoethanolamine metabolic process", "d": ["The chemical reactions and pathways involving ceramide phosphoethanolamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900675", "l": "regulation of F-9775B biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of F-9775B biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002333", "l": "transitional one stage B cell differentiation", "d": ["The process in which immature B cells from the bone marrow acquire the specialized features of T1 stage B cells in the spleen. T1 stage B cells do not express either CD23 or CD21."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018083", "l": "peptidyl-L-3-oxoalanine biosynthetic process from peptidyl-cysteine or peptidyl-serine", "d": ["The modification of peptidyl-cysteine or peptidyl-serine to peptidyl-L-3-oxoalanine; characteristic of the active sites of arylsulfatases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903125", "l": "negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation", "d": ["A peptidyl-threonine phosphorylation that results in negative regulation of thioredoxin peroxidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0070726", "l": "cell wall assembly", "d": ["The aggregation, arrangement and bonding together of a cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061385", "l": "fibroblast proliferation involved in heart morphogenesis", "d": ["The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080153", "l": "negative regulation of reductive pentose-phosphate cycle", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the reductive pentose-phosphate cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042421", "l": "norepinephrine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.618854952666041", "identifiers": [{"i": "GO:0000070", "l": "mitotic sister chromatid segregation", "d": ["The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0050812", "l": "regulation of acyl-CoA biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060355", "l": "positive regulation of cell adhesion molecule production", "d": ["Any process that increases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034297", "l": "oidium formation", "d": ["The process in which oidia, a type of asexual spore found in fungi, are formed. Oidia are borne a few at a time on very simple hyphae that protrude a short distance into the substrate, and are usually presumed not to constitute the main reproductive strategy of the fungus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021841", "l": "chemoattraction involved in interneuron migration from the subpallium to the cortex", "d": ["The creation and reception of signals that result in the movement of interneurons toward the signal, where this process is involved in migration from the subpallium to the cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:2000968", "l": "positive regulation of cell wall polysaccharide catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cell wall polysaccharide catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098757", "l": "cellular response to interleukin-21", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060190", "l": "negative regulation of protein desumoylation", "d": ["Any process that decreases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098671", "l": "adhesion receptor-mediated virion attachment to host cell", "d": ["The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that does not mediate or trigger entry into the host cell. This binding is typically reversible and enhances significantly infectivity by concentrating the virus in the vicinity of its entry receptors, or bringing it to an organ in which its target cells are located."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.780700721499244", "identifiers": [{"i": "GO:0007162", "l": "negative regulation of cell adhesion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019544", "l": "arginine catabolic process to glutamate", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including glutamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900758", "l": "negative regulation of D-amino-acid oxidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of D-amino-acid oxidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048162", "l": "multi-layer follicle stage", "d": ["The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060134", "l": "prepulse inhibition", "d": ["The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900999", "l": "nitrobenzene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nitrobenzene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900142", "l": "negative regulation of oligodendrocyte apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000532", "l": "regulation of renal albumin absorption", "d": ["Any process that modulates the frequency, rate or extent of renal albumin absorption."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0006901", "l": "vesicle coating", "d": ["A protein coat is added to the vesicle to form the proper shape of the vesicle and to target the vesicle for transport to its destination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905035", "l": "negative regulation of antifungal innate immune response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an antifungal innate immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0071384", "l": "cellular response to corticosteroid stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061871", "l": "negative regulation of hepatic stellate cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019384", "l": "caprolactam catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904276", "l": "regulation of wax biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of wax biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051613", "l": "positive regulation of serotonin uptake", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of serotonin into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009102", "l": "biotin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0060810", "l": "intracellular mRNA localization involved in pattern specification process", "d": ["Any process in which mRNA is transported to, or maintained in, a specific location within an oocyte that results in a pattern being established in the embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003119", "l": "regulation of vasoconstriction by neuronal epinephrine", "d": ["Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of epinephrine released by nerve endings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990314", "l": "cellular response to insulin-like growth factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903582", "l": "negative regulation of basophil degranulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of basophil degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032796", "l": "uropod organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a uropod, a rigid membrane projection with related cytoskeletal components at the trailing edge of a lymphocyte or other cell in the process of migrating or being activated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036321", "l": "ghrelin secretion", "d": ["The regulated release of ghrelin from a cell. Ghrelin is a 28 amino acid hunger-stimulating peptide hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.261087039309942", "identifiers": [{"i": "GO:0007548", "l": "sex differentiation", "d": ["The establishment of the sex of an organism by physical differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002434", "l": "immune complex clearance", "d": ["A process directed at removing immune complexes from the body. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072071", "l": "kidney interstitial fibroblast differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061854", "l": "positive regulation of neuroblast migration", "d": ["Any process that activates or increases the frequency, rate or extent of neuroblast migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0097393", "l": "telomeric repeat-containing RNA transcription", "d": ["The synthesis of telomeric repeat-containing RNA from a DNA template. A telomere is a complex of DNA and proteins that seals the end of a chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007536", "l": "activation of recombination (HML)", "d": ["The activation of recombination at a mating type locus, such that it is used in preference to the other donor locus for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097391", "l": "chemokine (C-X-C motif) ligand 13 production", "d": ["The appearance of chemokine (C-X-C motif) ligand 13 (CXCL13) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1900704", "l": "regulation of siderophore biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of siderophore biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900305", "l": "positive regulation of laminaritriose transport", "d": ["Any process that activates or increases the frequency, rate or extent of laminaritriose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902323", "l": "negative regulation of methyl-branched fatty acid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methyl-branched fatty acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900623", "l": "regulation of monocyte aggregation", "d": ["Any process that modulates the frequency, rate or extent of monocyte aggregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0018940", "l": "orcinol metabolic process", "d": ["The chemical reactions and pathways involving orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen, and synthesized, probably as a fungicide, by some higher plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900084", "l": "regulation of peptidyl-tyrosine autophosphorylation", "d": ["Any process that modulates the frequency, rate or extent of peptidyl-tyrosine autophosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.116918913335823", "identifiers": [{"i": "GO:0002889", "l": "regulation of immunoglobulin mediated immune response", "d": ["Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0003094", "l": "glomerular filtration", "d": ["The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.848316207395129", "identifiers": [{"i": "GO:0005976", "l": "polysaccharide metabolic process", "d": ["The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.062476272212777", "identifiers": [{"i": "GO:0035296", "l": "regulation of tube diameter", "d": ["Any process that modulates the diameter of a tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009604", "l": "detection of symbiotic bacterium", "d": ["The series of events in which a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism, is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905400", "l": "negative regulation of activated CD4-positive, alpha-beta T cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0008291", "l": "acetylcholine metabolic process", "d": ["The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000934", "l": "negative regulation of cellotriose metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006999", "l": "nuclear pore organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901454", "l": "regulation of response to toluene", "d": ["Any process that modulates the frequency, rate or extent of response to toluene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045645", "l": "positive regulation of eosinophil differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of eosinophil differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072649", "l": "interferon-kappa production", "d": ["The appearance of interferon-kappa due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048920", "l": "posterior lateral line neuromast primordium migration", "d": ["The migration of a relatively undifferentiated cell along the developing posterior lateral line, originating from cranial ectodermal placodes situated behind the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0090381", "l": "regulation of heart induction", "d": ["Any process that modulates the rate, frequency, or extent of heart induction. Heart induction is the close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035652", "l": "clathrin-coated vesicle cargo loading", "d": ["Formation of a macromolecular complex between the cytoplasmic coat proteins on clathrin-coated vesicles and proteins and/or lipoproteins that are going to be transported by a vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021971", "l": "corticospinal neuron axon guidance through the medullary pyramid", "d": ["The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the basilar pons through the medullary pyramid in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034253", "l": "positive regulation of amide catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044629", "l": "negative regulation of complement activation, classical pathway in another organism", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway, in a different organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106062", "l": "positive regulation of exit from meiosis", "d": ["Any process that activates or increases the frequency, rate or extent of exit from meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042167", "l": "heme catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904591", "l": "positive regulation of protein import", "d": ["Any process that activates or increases the frequency, rate or extent of protein import."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902960", "l": "negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036249", "l": "cadmium ion import into vacuole", "d": ["The directed movement of cadmium ions into the vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0090162", "l": "establishment of epithelial cell polarity", "d": ["The specification and formation of anisotropic intracellular organization of an epithelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0045990", "l": "carbon catabolite regulation of transcription", "d": ["A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099180", "l": "zinc ion import into synaptic vesicle", "d": ["The directed movement of Zn2+ ions from the cytoplasm into the lumen of a cytoplasmic vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030842", "l": "regulation of intermediate filament depolymerization", "d": ["Any process that modulates the frequency, rate or extent of the disassembly of intermediate filaments by the removal of monomers from a filament."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099562", "l": "maintenance of postsynaptic density structure", "d": ["A process which maintains the organization and the arrangement of proteins in the presynaptic density."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000518", "l": "negative regulation of T-helper 1 cell activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0010248", "l": "establishment or maintenance of transmembrane electrochemical gradient", "d": ["The directed movement of ions to establish or maintain an electrochemical gradient across a membrane by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061099", "l": "negative regulation of protein tyrosine kinase activity", "d": ["Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0070242", "l": "thymocyte apoptotic process", "d": ["Any apoptotic process in a thymocyte, an immature T cell located in the thymus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0031152", "l": "aggregation involved in sorocarp development", "d": ["The process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905004", "l": "picolinic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of picolinic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905414", "l": "negative regulation of dense core granule exocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990010", "l": "compound eye retinal cell apoptotic process", "d": ["Any apoptotic process in a compound eye retinal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019256", "l": "acrylonitrile catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0046503", "l": "glycerolipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycerolipids, any lipid with a glycerol backbone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045899", "l": "positive regulation of RNA polymerase II transcription preinitiation complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010059", "l": "positive regulation of atrichoblast fate specification", "d": ["Any process that induces or promotes atrichoblast fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035394", "l": "regulation of chemokine (C-X-C motif) ligand 9 production", "d": ["Any process that modulates the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0046958", "l": "nonassociative learning", "d": ["A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001177", "l": "regulation of transcription open complex formation at RNA polymerase II promoter", "d": ["Any process that modulates the rate, frequency or extent of a process involved the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042540", "l": "hemoglobin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin; especially, the proteolytic cleavage of hemoglobin to yield free heme, peptides, and amino acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098823", "l": "peptidyl-cysteine modification to S-amindino-L-cysteine", "d": ["The amidinylation of peptidyl-cysteine to form peptidyl-S-amidino-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031653", "l": "heat dissipation", "d": ["Any homeostatic process in which an organism releases excess heat to the environment, thereby lowering its internal temperature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000794", "l": "regulation of epithelial cell proliferation involved in lung morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902565", "l": "positive regulation of neutrophil activation", "d": ["Any process that activates or increases the frequency, rate or extent of neutrophil activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090511", "l": "periclinal cell division", "d": ["A cell division process where the division plane is parallel to the surface of the organ. It creates a new cell layer or cell file."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903428", "l": "positive regulation of reactive oxygen species biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0070228", "l": "regulation of lymphocyte apoptotic process", "d": ["Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002092", "l": "positive regulation of receptor internalization", "d": ["Any process that activates or increases the frequency, rate or extent of receptor internalization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042309", "l": "homoiothermy", "d": ["Any homoeostatic process in which an organism maintains its internal body temperature at a relatively constant value. This is achieved by using metabolic processes to counteract fluctuations in the temperature of the environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010801", "l": "negative regulation of peptidyl-threonine phosphorylation", "d": ["Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000679", "l": "positive regulation of transcription regulatory region DNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061143", "l": "alveolar primary septum development", "d": ["The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001743", "l": "lens placode formation", "d": ["The initial developmental process that will lead to the formation of an eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0071829", "l": "plasma lipoprotein particle disassembly", "d": ["The disaggregation of a plasma lipoprotein particle into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051617", "l": "negative regulation of histamine uptake", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of histamine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0003156", "l": "regulation of animal organ formation", "d": ["Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0039022", "l": "pronephric duct development", "d": ["The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901501", "l": "response to xylene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xylene stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.470950656012619", "identifiers": [{"i": "GO:0010562", "l": "positive regulation of phosphorus metabolic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.7920354431539", "identifiers": [{"i": "GO:0062012", "l": "regulation of small molecule metabolic process", "d": ["Any process that modulates the rate, frequency or extent of a small molecule metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016320", "l": "endoplasmic reticulum membrane fusion", "d": ["The joining of 2 or more lipid bilayer membranes that surround the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905285", "l": "fibrous ring of heart morphogenesis", "d": ["The developmental process by which a fibrous ring of heart is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010456", "l": "cell proliferation in dorsal spinal cord", "d": ["The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043418", "l": "homocysteine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046500", "l": "S-adenosylmethionine metabolic process", "d": ["The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120213", "l": "regulation of histidine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of histidine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006072", "l": "glycerol-3-phosphate metabolic process", "d": ["The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.572744119402742", "identifiers": [{"i": "GO:0022405", "l": "hair cycle process", "d": ["A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.927964040871231", "identifiers": [{"i": "GO:0002218", "l": "activation of innate immune response", "d": ["Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900306", "l": "regulation of maltoheptaose transport", "d": ["Any process that modulates the frequency, rate or extent of maltoheptaose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019600", "l": "toluene oxidation", "d": ["The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in toluene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090363", "l": "regulation of proteasome core complex assembly", "d": ["Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060734", "l": "regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation", "d": ["Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to endoplasmic reticulum stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070072", "l": "vacuolar proton-transporting V-type ATPase complex assembly", "d": ["The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000488", "l": "maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)", "d": ["Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032980", "l": "keratinocyte activation", "d": ["A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905645", "l": "negative regulation of FACT complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of FACT complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000465", "l": "regulation of glycogen (starch) synthase activity", "d": ["Any process that modulates the frequency, rate or extent of glycogen (starch) synthase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2001055", "l": "positive regulation of mesenchymal cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002519", "l": "natural killer cell tolerance induction", "d": ["Tolerance induction of natural killer cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0050868", "l": "negative regulation of T cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045600", "l": "positive regulation of fat cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of adipocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0051988", "l": "regulation of attachment of spindle microtubules to kinetochore", "d": ["Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.444551060876734", "identifiers": [{"i": "GO:0006364", "l": "rRNA processing", "d": ["Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045038", "l": "protein import into chloroplast thylakoid membrane", "d": ["The import of proteins into the chloroplast thylakoid membranes. Proteins that are destined for the thylakoid lumen require two uptake-targeting sequences: the first targets the protein to the stroma, and the second targets the protein from the stroma to the thylakoid lumen. Four separate thylakoid-import systems deal with the proteins once they are in the stroma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0030857", "l": "negative regulation of epithelial cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007485", "l": "imaginal disc-derived male genitalia development", "d": ["The process whose specific outcome is the progression of the male genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0008038", "l": "neuron recognition", "d": ["The process in which a neuronal cell in a multicellular organism interprets its surroundings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014059", "l": "regulation of dopamine secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of dopamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0051156", "l": "glucose 6-phosphate metabolic process", "d": ["The chemical reactions and pathways involving glucose 6-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-6."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904437", "l": "positive regulation of transferrin receptor binding", "d": ["Any process that activates or increases the frequency, rate or extent of transferrin receptor binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904450", "l": "positive regulation of aspartate secretion", "d": ["Any process that activates or increases the frequency, rate or extent of aspartate secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:1903708", "l": "positive regulation of hemopoiesis", "d": ["Any process that activates or increases the frequency, rate or extent of hemopoiesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070863", "l": "positive regulation of protein exit from endoplasmic reticulum", "d": ["Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106298", "l": "13-series resolvin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of resolvin family 13-series, hydroxy fatty acids derived from docosapentaenoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044314", "l": "protein K27-linked ubiquitination", "d": ["A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is added to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043607", "l": "formamide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of formamide, the simplest amide, HCONH2, derived from formic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046095", "l": "deoxyinosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of deoxyinosine, hypoxanthine deoxyriboside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0030474", "l": "spindle pole body duplication", "d": ["Construction of a new spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900626", "l": "regulation of arugosin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of arugosin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034503", "l": "protein localization to nucleolar rDNA repeats", "d": ["Any process in which a protein is transported to, or maintained at, the rDNA repeats on a chromosome in the nucleolus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001148", "l": "regulation of dipeptide transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of dipeptide transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0048854", "l": "brain morphogenesis", "d": ["The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010884", "l": "positive regulation of lipid storage", "d": ["Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060492", "l": "lung induction", "d": ["The close range interaction of two or more cells or tissues that causes the cells of the foregut to change their fates and specify the development of the lung."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019397", "l": "gallate catabolic process via 2-pyrone-4,6-dicarboxylate", "d": ["The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, via the intermediate 2-pyrone-4,6-dicarboxylate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044533", "l": "positive regulation of apoptotic process in another organism", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death by apoptosis in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904792", "l": "positive regulation of shelterin complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of shelterin complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903700", "l": "caecum development", "d": ["The process whose specific outcome is the progression of a caecum over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052201", "l": "response to symbiont defenses", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.585103934178449", "identifiers": [{"i": "GO:0051648", "l": "vesicle localization", "d": ["Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035212", "l": "cell competition in a multicellular organism", "d": ["Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990679", "l": "histone H4-K12 deacetylation", "d": ["The modification of histone H4 by the removal of an acetyl group from lysine at position 12 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097062", "l": "dendritic spine maintenance", "d": ["The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000129", "l": "negative regulation of octopamine signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060750", "l": "epithelial cell proliferation involved in mammary gland duct elongation", "d": ["The multiplication or reproduction of mammary gland branch epithelial cells, resulting in the elongation of the branch. The mammary gland branch differs from the bud in that it is not the initial curved portion of the outgrowth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990828", "l": "hepatocyte dedifferentiation", "d": ["The process in which a hepatocyte (specialized epithelial cell of the liver) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0072662", "l": "protein localization to peroxisome", "d": ["A process in which a protein is transported to, or maintained at, a location in a peroxisome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.837016147763222", "identifiers": [{"i": "GO:0002253", "l": "activation of immune response", "d": ["Any process that initiates an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045662", "l": "negative regulation of myoblast differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0009683", "l": "indoleacetic acid metabolic process", "d": ["The chemical reactions and pathways involving indole-3-acetic acid, a compound which functions as a growth regulator in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001032", "l": "regulation of double-strand break repair via nonhomologous end joining", "d": ["Any process that modulates the frequency, rate or extent of double-strand break repair via nonhomologous end joining."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042150", "l": "plasmid recombination", "d": ["A process of DNA recombination occurring within a plasmid or between plasmids and other plasmids or DNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0061615", "l": "glycolytic process through fructose-6-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:1902305", "l": "regulation of sodium ion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006268", "l": "DNA unwinding involved in DNA replication", "d": ["The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035789", "l": "metanephric mesenchymal cell migration", "d": ["The orderly movement of undifferentiated metanephric mesenchymal cells (precursors to metanephric mesangial cells) from the mesenchyme into the cleft of the developing glomerulus, during development of the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120309", "l": "cilium attachment to cell body", "d": ["A process that is carried out at the cellular level which results in the lateral attachment of the cilium to the cell body via the flagellar attachment zone in some trypanosomatid species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042268", "l": "regulation of cytolysis", "d": ["Any process that modulates the frequency, rate or extent of the rupture of cell membranes and the loss of cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034021", "l": "response to silicon dioxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900099", "l": "negative regulation of plasma cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plasma cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032756", "l": "positive regulation of interleukin-7 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-7 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903923", "l": "positive regulation of protein processing in phagocytic vesicle", "d": ["Any process that activates or increases the frequency, rate or extent of protein processing in phagocytic vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0090311", "l": "regulation of protein deacetylation", "d": ["Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0014876", "l": "response to injury involved in regulation of muscle adaptation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a injury. This process occurs as part of the regulation of muscle adaptation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072752", "l": "cellular response to rapamycin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021858", "l": "GABAergic neuron differentiation in basal ganglia", "d": ["The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic inhibitory neuron in the basal ganglia. Differentiation includes the processes involved in commitment of a neuroblast to a GABAergic neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090423", "l": "phytochelatin-metal complex formation", "d": ["A phytochelatin metabolic process in which a metal is incorporated with phytochelatin to form a complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006532", "l": "aspartate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045313", "l": "rhabdomere membrane biogenesis", "d": ["A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a rhabdomere membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0014075", "l": "response to amine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044478", "l": "envenomation resulting in positive regulation of platelet aggregation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of platelet aggregation in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0106020", "l": "regulation of vesicle docking", "d": ["Any process that modulates the frequency, rate or extent of vesicle docking."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902988", "l": "neurofibrillary tangle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a neurofibrillary tangle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0007472", "l": "wing disc morphogenesis", "d": ["The process in which the anatomical structures derived from the wing disc are generated and organized. This includes the transformation of a wing imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the wing hinge, wing blade and pleura."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0042814", "l": "monopolar cell growth", "d": ["Polarized growth from one end of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905791", "l": "negative regulation of mechanosensory behavior", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mechanosensory behavior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0051494", "l": "negative regulation of cytoskeleton organization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905884", "l": "negative regulation of triglyceride transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of triglyceride transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051042", "l": "negative regulation of calcium-independent cell-cell adhesion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-independent cell-cell adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071332", "l": "cellular response to fructose stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902445", "l": "regulation of mitochondrial membrane permeability involved in programmed necrotic cell death", "d": ["Any regulation of mitochondrial membrane permeability that is involved in programmed necrotic cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001662", "l": "behavioral fear response", "d": ["An acute behavioral change resulting from a perceived external threat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0043370", "l": "regulation of CD4-positive, alpha-beta T cell differentiation", "d": ["Any process that modulates the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048777", "l": "positive regulation of leucophore differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of leucophore differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0032365", "l": "intracellular lipid transport", "d": ["The directed movement of lipids within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0008214", "l": "protein dealkylation", "d": ["The removal of an alkyl group from a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051682", "l": "galactomannan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061418", "l": "regulation of transcription from RNA polymerase II promoter in response to hypoxia", "d": ["Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0021800", "l": "cerebral cortex tangential migration", "d": ["The migration of cells in the cerebral cortex in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000218", "l": "negative regulation of invasive growth in response to glucose limitation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of invasive growth in response to glucose limitation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0071326", "l": "cellular response to monosaccharide stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070649", "l": "formin-nucleated actin cable assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070544", "l": "histone H3-K36 demethylation", "d": ["The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061190", "l": "regulation of sclerotome development", "d": ["Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0018992", "l": "germ-line sex determination", "d": ["The determination of sex and sexual phenotype in an organism's germ line."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046077", "l": "dUDP metabolic process", "d": ["The chemical reactions and pathways involving dUDP, deoxyuridine (5'-)diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:1903119", "l": "protein localization to actin cytoskeleton", "d": ["A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:1902019", "l": "regulation of cilium-dependent cell motility", "d": ["Any process that modulates the frequency, rate or extent of cilium-dependent cell motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904918", "l": "transmembrane L-histidine transport from lysosomal lumen to cytosol", "d": ["The directed movement of L-histidine from the lysosomal lumen across the lysosomal membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010866", "l": "regulation of triglyceride biosynthetic process", "d": ["Any process that modulates the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0016441", "l": "post-transcriptional gene silencing", "d": ["The inactivation of gene expression that occurs after transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900211", "l": "regulation of mesenchymal cell apoptotic process involved in metanephros development", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015787", "l": "UDP-glucuronic acid transmembrane transport", "d": ["The directed movement of UDP-glucuronic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903196", "l": "negative regulation of L-dopa biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021752", "l": "inferior salivary nucleus development", "d": ["The process whose specific outcome is the progression of the inferior salivary nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036099", "l": "female germ-line stem cell population maintenance", "d": ["The process by which an organism or tissue maintains a population of female germ-line stem cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003223", "l": "ventricular compact myocardium morphogenesis", "d": ["The process in which the anatomical structures of the compact cardiac ventricle muscle are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0002864", "l": "regulation of acute inflammatory response to antigenic stimulus", "d": ["Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0006267", "l": "pre-replicative complex assembly involved in nuclear cell cycle DNA replication", "d": ["The aggregation, arrangement and bonding together of a set of components to form the nuclear pre-replicative complex, a protein-DNA complex that forms at the eukaryotic DNA replication origin and is required for replication initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:2000988", "l": "regulation of hemicellulose catabolic process", "d": ["Any process that modulates the frequency, rate or extent of hemicellulose catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905562", "l": "regulation of vascular endothelial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1904292", "l": "regulation of ERAD pathway", "d": ["Any process that modulates the frequency, rate or extent of ERAD pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046295", "l": "glycolate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycolate, the anion of hydroxyethanoic acid (glycolic acid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045753", "l": "negative regulation of acetate catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048387", "l": "negative regulation of retinoic acid receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098867", "l": "intramembranous bone growth", "d": ["The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901940", "l": "(-)-exo-alpha-bergamotene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (-)-exo-alpha-bergamotene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0061515", "l": "myeloid cell development", "d": ["The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061172", "l": "regulation of establishment of bipolar cell polarity", "d": ["Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity. Bipolar organization is the organization that is a mirror image along an axis from a plane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015974", "l": "guanosine pentaphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061528", "l": "aspartate secretion", "d": ["The regulated release of aspartate by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061541", "l": "rhabdomere morphogenesis", "d": ["The process in which the anatomical structures of a rhabdomere are generated and organized. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0046640", "l": "regulation of alpha-beta T cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of alpha-beta T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0035914", "l": "skeletal muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0048844", "l": "artery morphogenesis", "d": ["The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.987832356016085", "identifiers": [{"i": "GO:0006497", "l": "protein lipidation", "d": ["The covalent attachment of lipid groups to an amino acid in a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016258", "l": "N-glycan diversification", "d": ["The generation, in the Golgi apparatus, of side chain diversity from high mannose Man5GlcNAc2-Asn N-glycans by specific glycosyltransferases and glycosidases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903841", "l": "cellular response to arsenite(3-)", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903938", "l": "cellular response to acrylamide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010111", "l": "glyoxysome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the glyoxysome. A glyoxysome is a microbody that contains the enzymes of the glyoxylate pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060309", "l": "elastin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of elastin. Elastin is a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035519", "l": "protein K29-linked ubiquitination", "d": ["A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is added to a protein. K29-linked ubiquitination targets the substrate protein for degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.892466024748572", "identifiers": [{"i": "GO:0046545", "l": "development of primary female sexual characteristics", "d": ["The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032304", "l": "negative regulation of icosanoid secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of an icosanoid from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0014037", "l": "Schwann cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046282", "l": "cinnamic acid ester catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ester derivatives of cinnamic acid, phenylpropenoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097492", "l": "sympathetic neuron axon guidance", "d": ["The chemotaxis process that directs the migration of a sympathetic neuron axon growth cone to a specific target site in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0002183", "l": "cytoplasmic translational initiation", "d": ["The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033119", "l": "negative regulation of RNA splicing", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060013", "l": "righting reflex", "d": ["A reflex process in which an animal immediately tries to turn over after being placed in a supine position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0062149", "l": "detection of stimulus involved in sensory perception of pain", "d": ["The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901384", "l": "positive regulation of chorionic trophoblast cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0045730", "l": "respiratory burst", "d": ["A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097656", "l": "cell-cell self recognition", "d": ["A cell-cell recognition process by which a cell distinguishes between self and non self during cooperative behavior, such as early development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902366", "l": "regulation of Notch signaling pathway involved in somitogenesis", "d": ["Any process that modulates the frequency, rate or extent of Notch signaling pathway involved in somitogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904289", "l": "regulation of mitotic DNA damage checkpoint", "d": ["Any process that modulates the frequency, rate or extent of mitotic DNA damage checkpoint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903540", "l": "establishment of protein localization to postsynaptic membrane", "d": ["The directed movement of a protein to a specific location in a postsynaptic membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0048599", "l": "oocyte development", "d": ["The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0015743", "l": "malate transport", "d": ["The directed movement of malate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050857", "l": "positive regulation of antigen receptor-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0061620", "l": "glycolytic process through glucose-6-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, occurring through a glucose-6-phosphate intermediate, with the concomitant production of a small amount of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002324", "l": "natural killer cell proliferation involved in immune response", "d": ["The expansion of a natural killer cell population by cell division as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.260243218047506", "identifiers": [{"i": "GO:0044380", "l": "protein localization to cytoskeleton", "d": ["A process in which a protein is transported to, or maintained in, a location within the cytoskeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010865", "l": "stipule development", "d": ["The process whose specific outcome is the progression of the stipule over time, from its formation to the mature structure. A stipule is one of (usually) a pair of appendages at the bases of leaves in many broad-leaved angiosperms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048260", "l": "positive regulation of receptor-mediated endocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051835", "l": "positive regulation of synapse structural plasticity", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of synaptic structural plasticity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016080", "l": "synaptic vesicle targeting", "d": ["The process in which synaptic vesicles are directed to specific destination membranes, mediated by molecules at the vesicle membrane and target membrane surfaces."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061182", "l": "negative regulation of chondrocyte development", "d": ["Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901519", "l": "aspyridone B metabolic process", "d": ["The chemical reactions and pathways involving aspyridone B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010405", "l": "arabinogalactan protein metabolic process", "d": ["The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein of highly varying length and domain complexity. These are O-glycosylated at one or more hydroxyproline residues by arabinogalactan (AG) type II groups, which consist of (1->3)-beta-galactan and (1->6)-beta-linked galactan chains connected to each other by (1->3,1->6)-linked branch points, O-3 and O-6 positions substituted with terminal arabinosyl residues. Also, rhamnose, fucose, glucuronic and galacturonic acid can be present in the glycan structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009768", "l": "photosynthesis, light harvesting in photosystem I", "d": ["After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem I, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902701", "l": "pentose catabolic process to propan-2-ol", "d": ["The chemical reactions and pathways resulting in the breakdown of pentose to propan-2-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0018108", "l": "peptidyl-tyrosine phosphorylation", "d": ["The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902522", "l": "response to 4'-epidoxorubicin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4'-epidoxorubicin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018005", "l": "N-terminal peptidyl-glycine N-formylation", "d": ["The formylation of the N-terminal glycine of proteins to form the derivative N-formylglycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031947", "l": "negative regulation of glucocorticoid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050887", "l": "determination of sensory modality", "d": ["The determination of the type or quality of a sensation. Sensory modalities include touch, thermal sensation, visual sensation, auditory sensation and pain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0061550", "l": "cranial ganglion development", "d": ["The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905810", "l": "regulation of excitatory synapse pruning", "d": ["Any process that modulates the frequency, rate or extent of excitatory synapse pruning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0006957", "l": "complement activation, alternative pathway", "d": ["Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0007520", "l": "myoblast fusion", "d": ["A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1990986", "l": "DNA recombinase disassembly", "d": ["The disaggregation of a DNA recombinase complex into its constituent strand exchange proteins (recombinases)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046317", "l": "regulation of glucosylceramide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901614", "l": "positive regulation of terminal button organization", "d": ["Any process that activates or increases the frequency, rate or extent of terminal button organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018266", "l": "GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-aspartic acid ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a aspartyl-peptide bond in the carboxy-terminal region of a membrane-associated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901397", "l": "positive regulation of transforming growth factor beta2 activation", "d": ["Any process that activates or increases the frequency, rate or extent of transforming growth factor beta2 activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036297", "l": "interstrand cross-link repair", "d": ["Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009860", "l": "pollen tube growth", "d": ["Growth of pollen via tip extension of the intine wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070206", "l": "protein trimerization", "d": ["The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060569", "l": "positive regulation of peptide hormone processing", "d": ["Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0090398", "l": "cellular senescence", "d": ["A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest."]}]}
{"type": "biolink:BiologicalProcess", "ic": "45.021490516424151", "identifiers": [{"i": "GO:0034220", "l": "monoatomic ion transmembrane transport", "d": ["A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.654352968788714", "identifiers": [{"i": "GO:0006897", "l": "endocytosis", "d": ["A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905218", "l": "cellular response to astaxanthin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032122", "l": "oral apparatus organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the oral apparatus. The oral apparatus is a funnel-like structure used by the cell to collect food and channel it to the cytostome, characteristic of ciliate protozoans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052091", "l": "modulation of nutrient release by host", "d": ["Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.523519163150823", "identifiers": [{"i": "GO:0007159", "l": "leukocyte cell-cell adhesion", "d": ["The attachment of a leukocyte to another cell via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "44.803869458096429", "identifiers": [{"i": "GO:0046483", "l": "heterocycle metabolic process", "d": ["The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904270", "l": "pyroptosome complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a pyroptosome complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900163", "l": "positive regulation of phospholipid scramblase activity", "d": ["Any process that activates or increases the frequency, rate or extent of phospholipid scramblase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0016203", "l": "muscle attachment", "d": ["The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060687", "l": "regulation of branching involved in prostate gland morphogenesis", "d": ["Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010049", "l": "acquisition of plant reproductive competence", "d": ["The process in which a plant acquires the ability to respond to a floral inductive signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046007", "l": "negative regulation of activated T cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035719", "l": "tRNA import into nucleus", "d": ["The directed movement of tRNA from the cytoplasm to the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900583", "l": "o-orsellinic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of o-orsellinic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009197", "l": "pyrimidine deoxyribonucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042046", "l": "W-molybdopterin cofactor metabolic process", "d": ["The chemical reactions and pathways involving the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0023002", "l": "nuclear migration to embryo sac poles", "d": ["Migration of the nuclei of the two-nucleate embryo sac to opposite poles of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061935", "l": "fusion of sperm to egg plasma membrane involved in double fertilization forming two zygotes", "d": ["The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming two zygotes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070474", "l": "positive regulation of uterine smooth muscle contraction", "d": ["Any process that increases the frequency, rate or extent of uterine smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903774", "l": "positive regulation of viral budding via host ESCRT complex", "d": ["Any process that activates or increases the frequency, rate or extent of viral budding via host ESCRT complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045208", "l": "MAPK phosphatase export from nucleus", "d": ["The directed movement of a MAPK phosphatase from the nucleus to the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901509", "l": "regulation of endothelial tube morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051519", "l": "activation of bipolar cell growth", "d": ["Any process that initiates the inactive process of bipolar cell growth, polarized growth from both ends of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002322", "l": "B cell proliferation involved in immune response", "d": ["The expansion of a B cell population by cell division following B cell activation during an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.155424086811493", "identifiers": [{"i": "GO:0035270", "l": "endocrine system development", "d": ["Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021927", "l": "deep nuclear neuron precursor proliferation", "d": ["The multiplication or reproduction of neuroblasts that will give rise to deep nuclear neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0031623", "l": "receptor internalization", "d": ["A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014849", "l": "ureter smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0044319", "l": "wound healing, spreading of cells", "d": ["The migration of a cell along or through a wound gap that contributes to the reestablishment of a continuous surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0061440", "l": "kidney vasculature development", "d": ["The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002278", "l": "eosinophil activation involved in immune response", "d": ["The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034193", "l": "L-galactonate metabolic process", "d": ["The chemical reactions and pathways involving L-galactonate, the anion of L-galactonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0098876", "l": "vesicle-mediated transport to the plasma membrane", "d": ["The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044643", "l": "envenomation resulting in positive regulation of complement activation, alternative pathway in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the alternative pathway in the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007522", "l": "visceral muscle development", "d": ["The process whose specific outcome is the progression of the visceral muscle over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099041", "l": "vesicle tethering to Golgi", "d": ["The initial, indirect interaction between a transport vesicle membrane and the membrane of the Golgi. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:1904064", "l": "positive regulation of cation transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of cation transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0055059", "l": "asymmetric neuroblast division", "d": ["The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:1903555", "l": "regulation of tumor necrosis factor superfamily cytokine production", "d": ["Any process that modulates the frequency, rate or extent of tumor necrosis factor superfamily cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045196", "l": "establishment or maintenance of neuroblast polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001326", "l": "replication of extrachromosomal circular DNA", "d": ["Replication of circular DNA following excision from the chromosome; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070304", "l": "positive regulation of stress-activated protein kinase signaling cascade", "d": ["Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160022", "l": "apocrine secretion", "d": ["The controlled release of a substance by a cell or a tissue by discharging a portion of the secreting cell when intracellular components are freed into a lumen through the shedding of whole pieces of the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0099541", "l": "trans-synaptic signaling by lipid", "d": ["Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097754", "l": "clathrin-mediated membrane bending", "d": ["A membrane bending process mediated by clathrin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990146", "l": "protein localization to rhabdomere", "d": ["A process in which a protein is transported to, or maintained in, a location within a rhabdomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046947", "l": "hydroxylysine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901586", "l": "negative regulation of acid-sensing ion channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of acid-sensing ion channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.777964009505382", "identifiers": [{"i": "GO:0060179", "l": "male mating behavior", "d": ["The specific behavior of a male organism that is associated with reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.659081121638913", "identifiers": [{"i": "GO:0030098", "l": "lymphocyte differentiation", "d": ["The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071586", "l": "CAAX-box protein processing", "d": ["The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:2001258", "l": "negative regulation of cation channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cation channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030511", "l": "positive regulation of transforming growth factor beta receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071258", "l": "cellular response to gravity", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0050996", "l": "positive regulation of lipid catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035342", "l": "positive regulation of inosine transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045498", "l": "sex comb development", "d": ["The process whose specific outcome is the progression of the sex comb over time, from its formation to the mature structure. The sex combs are the male specific chaetae located on the prothoracic tarsal segment of the prothoracic leg."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904632", "l": "cellular response to glucoside", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0006695", "l": "cholesterol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900213", "l": "positive regulation of mesenchymal cell apoptotic process involved in metanephros development", "d": ["Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.594043123901756", "identifiers": [{"i": "GO:0006637", "l": "acyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000054", "l": "negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901757", "l": "butirosin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of butirosin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0016333", "l": "morphogenesis of follicular epithelium", "d": ["The process in which the anatomical structures of a follicular epithelium are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905164", "l": "positive regulation of phagosome maturation", "d": ["Any process that activates or increases the frequency, rate or extent of phagosome maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:1903900", "l": "regulation of viral life cycle", "d": ["Any process that modulates the frequency, rate or extent of viral life cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006044", "l": "N-acetylglucosamine metabolic process", "d": ["The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.744066580938323", "identifiers": [{"i": "GO:0051703", "l": "biological process involved in intraspecies interaction between organisms", "d": ["Any process in which an organism has an effect on an organism of the same species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.444551060876734", "identifiers": [{"i": "GO:0046189", "l": "phenol-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048907", "l": "anterior lateral line ganglion development", "d": ["The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905923", "l": "positive regulation of acetylcholine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098786", "l": "biofilm matrix disassembly", "d": ["A process that results in the disassembly of a biofilm matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106021", "l": "negative regulation of vesicle docking", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle docking."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905079", "l": "regulation of cerebellar neuron development", "d": ["Any process that modulates the frequency, rate or extent of cerebellar neuron development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0002536", "l": "respiratory burst involved in inflammatory response", "d": ["A phase of elevated metabolic activity, during which oxygen consumption increases following a stimulus as part of an inflammatory response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, resulting in an increase in their intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0002340", "l": "central B cell selection", "d": ["Any B cell selection process that occurs in the bone marrow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051443", "l": "positive regulation of ubiquitin-protein transferase activity", "d": ["Any process that activates, maintains or increases the rate of ubiquitin transferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000922", "l": "negative regulation of arabinoxylan-containing compound catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of arabinoxylan-containing compound catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010200", "l": "response to chitin", "d": ["A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0090303", "l": "positive regulation of wound healing", "d": ["Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061114", "l": "branching involved in pancreas morphogenesis", "d": ["The process in which the branches of the pancreas are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0101018", "l": "negative regulation of mitotic DNA replication initiation from late origin", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061049", "l": "cell growth involved in cardiac muscle cell development", "d": ["The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035169", "l": "lymph gland plasmatocyte differentiation", "d": ["The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000353", "l": "formation of quadruple SL/U4/U5/U6 snRNP", "d": ["Formation of a quadruple snRNP complex composed of the spliced leader (SL) RNA along with the U4/U6-U5 tri-snRNP complex. Interactions that may facilitate this include a duplex between the SL and U6 RNAs and interactions between the U5 RNA and the exon sequence at the 5' splice site within the SL RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072275", "l": "metanephric glomerulus morphogenesis", "d": ["The process in which the anatomical structures of the metanephric glomerulus are generated and organized. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032207", "l": "regulation of telomere maintenance via recombination", "d": ["Any process that modulates the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:2000050", "l": "regulation of non-canonical Wnt signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007449", "l": "proximal/distal pattern formation, imaginal disc", "d": ["The establishment, maintenance and elaboration of the proximal/distal axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901695", "l": "tyramine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tyramine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0035266", "l": "meristem growth", "d": ["The increase in size or mass of a meristem, a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902339", "l": "positive regulation of apoptotic process involved in morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045222", "l": "CD4 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CD4, a CD marker that occurs on T-helper cells and is involved in MHC class II restricted interactions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042203", "l": "toluene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060577", "l": "pulmonary vein morphogenesis", "d": ["The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009554", "l": "megasporogenesis", "d": ["The process in which the megasporocyte undergoes meiosis, giving rise to four haploid megaspores in the nucellus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071040", "l": "nuclear polyadenylation-dependent antisense transcript catabolic process", "d": ["The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an antisense transcript, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target antisense transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.210020382616207", "identifiers": [{"i": "GO:0080090", "l": "regulation of primary metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071311", "l": "cellular response to acetate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0001779", "l": "natural killer cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a natural killer cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060929", "l": "atrioventricular node cell fate commitment", "d": ["The commitment of cells to atrioventricular (AV) node cell fates and their capacity to differentiate into AV node cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043096", "l": "purine nucleobase salvage", "d": ["Any process that generates purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from derivatives of them without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905498", "l": "positive regulation of triplex DNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of triplex DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002115", "l": "store-operated calcium entry", "d": ["A calcium ion entry mechanism in the plasma membrane activated by the depletion of calcium ion from the internal calcium ion store in the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900630", "l": "methanophenazine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of methanophenazine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061974", "l": "perichondral bone morphogenesis", "d": ["The process in which bones are generated and organized as a result of the conversion of initial connective tissue surrounding cartilage into bone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0030282", "l": "bone mineralization", "d": ["The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.980302069293842", "identifiers": [{"i": "GO:1902679", "l": "negative regulation of RNA biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:1903321", "l": "negative regulation of protein modification by small protein conjugation or removal", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein modification by small protein conjugation or removal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0008078", "l": "mesodermal cell migration", "d": ["The orderly movement of mesodermal cells from one site to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.356779217613806", "identifiers": [{"i": "GO:0051216", "l": "cartilage development", "d": ["The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001120", "l": "protein-DNA complex remodeling", "d": ["The acquisition, loss, or modification of macromolecules within a protein-DNA complex, resulting in the alteration of an existing complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0075198", "l": "modulation of symbiont haustorium neck formation for entry into host", "d": ["Any process that modulates the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080187", "l": "floral organ senescence", "d": ["The last stage of flower development during which programmed degradation of macromolecules and nutrient recycling take place."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0048240", "l": "sperm capacitation", "d": ["A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900354", "l": "regulation of methanofuran metabolic process", "d": ["Any process that modulates the frequency, rate or extent of methanofuran metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046679", "l": "response to streptomycin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905685", "l": "negative regulation of plasma membrane repair", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0000022", "l": "mitotic spindle elongation", "d": ["The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061343", "l": "cell adhesion involved in heart morphogenesis", "d": ["The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003216", "l": "cardiac left atrium formation", "d": ["The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0070873", "l": "regulation of glycogen metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046358", "l": "butyrate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of butyrate, the anion of butyric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902020", "l": "negative regulation of cilium-dependent cell motility", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000179", "l": "positive regulation of neural precursor cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007421", "l": "stomatogastric nervous system development", "d": ["The process whose specific outcome is the progression of the stomatogastric nervous system over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.142364941642427", "identifiers": [{"i": "GO:0006366", "l": "transcription by RNA polymerase II", "d": ["The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0043487", "l": "regulation of RNA stability", "d": ["Any process that modulates the propensity of RNA molecules to degradation. Includes processes that both stabilize and destabilize RNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035903", "l": "cellular response to immobilization stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0044114", "l": "development of symbiont in host", "d": ["The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.071082486141265", "identifiers": [{"i": "GO:0034329", "l": "cell junction assembly", "d": ["A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019411", "l": "aerobic respiration, using ferrous ions as electron donor", "d": ["The metabolic process in which ferrous ions (Fe2+) are oxidized to ferric ions (Fe3+) to generate energy, coupled to the reduction of carbon dioxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070778", "l": "L-aspartate transmembrane transport", "d": ["The directed movement of L-aspartate across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036071", "l": "N-glycan fucosylation", "d": ["The process of transferring a fucosyl group to an N-glycan. An N-glycan is the carbohydrate portion of an N-glycoprotein when attached to a nitrogen from asparagine or arginine side-chains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035695", "l": "mitophagy by induced vacuole formation", "d": ["The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021828", "l": "gonadotrophin-releasing hormone neuronal migration to the hypothalamus", "d": ["The directional movement of a gonadotrophin-releasing hormone producing neuron from the nasal placode to the hypothalamus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0055122", "l": "response to very low light intensity stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901430", "l": "positive regulation of syringal lignin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of syringal lignin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055109", "l": "invagination involved in gastrulation with mouth forming second", "d": ["The infolding of the epithelial sheet into the embryo involved in deuterostomic gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070999", "l": "detection of mechanical stimulus involved in sensory perception of gravity", "d": ["The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0000084", "l": "mitotic S phase", "d": ["The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072322", "l": "protein transport across periplasmic space", "d": ["The directed movement of proteins from the plasma membrane across the periplasmic space to the outer membrane or cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905644", "l": "regulation of FACT complex assembly", "d": ["Any process that modulates the frequency, rate or extent of FACT complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901085", "l": "pyrrolizidine alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrrolizidine alkaloid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043977", "l": "histone H2A-K5 acetylation", "d": ["The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 5 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021518", "l": "spinal cord commissural neuron specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a commissural neuron in an environment that is neutral with respect to the developmental pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035203", "l": "regulation of lamellocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0099118", "l": "microtubule-based protein transport", "d": ["A microtubule-based process that results in the transport of proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0060012", "l": "synaptic transmission, glycinergic", "d": ["The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050669", "l": "negative regulation of homocysteine metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving homocysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902874", "l": "positive regulation of horizontal cell localization", "d": ["Any process that activates or increases the frequency, rate or extent of horizontal cell localization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090190", "l": "positive regulation of branching involved in ureteric bud morphogenesis", "d": ["Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150007", "l": "clathrin-dependent synaptic vesicle endocytosis", "d": ["Clathrin-dependent endocytosis of presynaptic membrane regions comprising synaptic vesicles' membrane constituents. This is a relatively slow process occurring in the range of tens of seconds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.050408934017838", "identifiers": [{"i": "GO:0071363", "l": "cellular response to growth factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902921", "l": "poly(hydroxyvalerate) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(hydroxyvalerate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010401", "l": "pectic galactan metabolic process", "d": ["The chemical reactions and pathways involving galactan, a polymer of D-galactosyl units that can be found as a side chain of the pectin rhamnogalacturonan I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036346", "l": "cellular response to L-cysteine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus. L-cysteine is an optically active form of cysteine having L-configuration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060460", "l": "left lung morphogenesis", "d": ["The process in which anatomical structures of the left lung are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071073", "l": "positive regulation of phospholipid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002616", "l": "regulation of macrophage antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900067", "l": "regulation of cellular response to alkaline pH", "d": ["Any process that modulates the frequency, rate or extent of cellular response to alkalinity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106013", "l": "negative regulation of protein localization to cell cortex of cell tip", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the cell cortex of the cell tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901003", "l": "negative regulation of fermentation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fermentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.990900157612501", "identifiers": [{"i": "GO:0097529", "l": "myeloid leukocyte migration", "d": ["The movement of a myeloid leukocyte within or between different tissues and organs of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0018941", "l": "organomercury metabolic process", "d": ["The chemical reactions and pathways involving organomercury compound, any organic compound containing a mercury atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046292", "l": "formaldehyde metabolic process", "d": ["The chemical reactions and pathways involving formaldehyde (methanal, H2C=O), a colorless liquid or gas with a pungent odor, commonly used as a fixative or an antibacterial agent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0016095", "l": "polyprenol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.94812697248932", "identifiers": [{"i": "GO:0016053", "l": "organic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075258", "l": "negative regulation of teliospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901010", "l": "(S)-reticuline metabolic process", "d": ["The chemical reactions and pathways involving (S)-reticuline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071698", "l": "olfactory placode development", "d": ["The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:1901804", "l": "beta-glucoside metabolic process", "d": ["The chemical reactions and pathways involving beta-glucoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0003091", "l": "renal water homeostasis", "d": ["Renal process involved in the maintenance of an internal steady state of water in the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902038", "l": "positive regulation of hematopoietic stem cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034051", "l": "negative regulation of plant-type hypersensitive response", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the hypersensitive response in a plant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900481", "l": "negative regulation of diacylglycerol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903710", "l": "spermine transmembrane transport", "d": ["The process in which spermine is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000214", "l": "regulation of proline metabolic process", "d": ["Any process that modulates the frequency, rate or extent of proline metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046475", "l": "glycerophospholipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071361", "l": "cellular response to ethanol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0007190", "l": "activation of adenylate cyclase activity", "d": ["Any process that initiates the activity of the inactive enzyme adenylate cyclase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021529", "l": "spinal cord oligodendrocyte cell differentiation", "d": ["The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050788", "l": "sequestering of mercury", "d": ["The process of binding or confining toxic mercury ions or atoms such that they are separated from sensitive components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002350", "l": "peripheral B cell positive selection", "d": ["Any process leading to positive selection of B cells in the periphery. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031140", "l": "induction of conjugation upon nutrient starvation", "d": ["The process in which a cell initiates conjugation with cellular fusion upon starvation for one or more nutrients."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010407", "l": "non-classical arabinogalactan protein metabolic process", "d": ["The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein where other amino acids besides Hyp, Ala, Ser, Thr and Gly can be present and grouped into regions, such as a Cys-rich or Asn-rich domains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904378", "l": "maintenance of unfolded protein involved in ERAD pathway", "d": ["Maintaining an endoplasmic reticulum (ER) protein in an unfolded, soluble state that contributes to its degradation by the cytoplasmic proteasome. Maintaining ER-resident proteins in an unfolded yet soluble state condition after their retro-translocation favors their turnover by the cytosolic proteasome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000717", "l": "positive regulation of maintenance of mitotic sister chromatid cohesion, arms", "d": ["Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051895", "l": "negative regulation of focal adhesion assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045429", "l": "positive regulation of nitric oxide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:1904745", "l": "Atg1/ULK1 kinase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an Atg1/UKL1 kinase complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902266", "l": "intracellular abscisic acid homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of abscisic acid within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072261", "l": "metanephric extraglomerular mesangial cell proliferation involved in metanephros development", "d": ["The multiplication or reproduction of extraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0002887", "l": "negative regulation of myeloid leukocyte mediated immunity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905624", "l": "regulation of L-methionine import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of L-methionine import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0001117", "l": "protein-DNA-RNA complex disassembly", "d": ["The disaggregation of a protein-DNA-RNA complex into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048648", "l": "caste determination", "d": ["The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental and/or genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051521", "l": "termination of monopolar cell growth", "d": ["Any process that stops the active process of bipolar cell growth, polarized growth from one end of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0002510", "l": "central B cell tolerance induction", "d": ["Tolerance induction of B cells in the bone marrow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.468544520863134", "identifiers": [{"i": "GO:0018209", "l": "peptidyl-serine modification", "d": ["The modification of peptidyl-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902767", "l": "isoprenoid biosynthetic process via mevalonate", "d": ["The chemical reactions and pathways resulting in the formation of isoprenoid via mevalonate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035887", "l": "aortic smooth muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046607", "l": "positive regulation of centrosome cycle", "d": ["Any process that activates or increases the frequency, rate or extent of the centrosome cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900958", "l": "positive regulation of 17-methylnonadec-1-ene biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046359", "l": "butyrate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of butyrate, the anion of butyric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0021825", "l": "substrate-dependent cerebral cortex tangential migration", "d": ["The process where neuronal precursors migrate tangentially in the cerebral cortex, primarily guided through physical cell-cell interactions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046829", "l": "negative regulation of RNA import into nucleus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002305", "l": "CD8-positive, gamma-delta intraepithelial T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0051458", "l": "corticotropin secretion", "d": ["The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900493", "l": "positive regulation of [4Fe-4S] cluster assembly", "d": ["Any process that activates or increases the frequency, rate or extent of [4Fe-4S] cluster assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0016998", "l": "cell wall macromolecule catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of macromolecules that form part of a cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010439", "l": "regulation of glucosinolate biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071951", "l": "conversion of methionyl-tRNA to N-formyl-methionyl-tRNA", "d": ["The modification process that results in the conversion of methionine charged on a tRNA(fMet) to N-formyl-methionine-tRNA(fMet)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045016", "l": "mitochondrial magnesium ion transmembrane transport", "d": ["The process in which a magnesium ion (Mg2+) is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019288", "l": "isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway", "d": ["The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0071402", "l": "cellular response to lipoprotein particle stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0051782", "l": "negative regulation of cell division", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900582", "l": "o-orsellinic acid metabolic process", "d": ["The chemical reactions and pathways involving o-orsellinic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:2000779", "l": "regulation of double-strand break repair", "d": ["Any process that modulates the frequency, rate or extent of double-strand break repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.468544520863134", "identifiers": [{"i": "GO:0001582", "l": "detection of chemical stimulus involved in sensory perception of sweet taste", "d": ["The series of events required for a sweet taste stimulus to be received and converted to a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060225", "l": "positive regulation of retinal rod cell fate commitment", "d": ["Any process that increases the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009304", "l": "tRNA transcription", "d": ["The synthesis of transfer RNA (tRNA) from a DNA template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0016325", "l": "oocyte microtubule cytoskeleton organization", "d": ["Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.470950656012619", "identifiers": [{"i": "GO:0031331", "l": "positive regulation of cellular catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902883", "l": "negative regulation of response to oxidative stress", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002176", "l": "male germ cell proliferation", "d": ["The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.338826399587582", "identifiers": [{"i": "GO:0042981", "l": "regulation of apoptotic process", "d": ["Any process that modulates the occurrence or rate of cell death by apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051565", "l": "negative regulation of smooth endoplasmic reticulum calcium ion concentration", "d": ["Any process that decreases the concentration of calcium ions in the smooth endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904246", "l": "negative regulation of polynucleotide adenylyltransferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of polynucleotide adenylyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903603", "l": "thermospermine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of thermospermine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0045141", "l": "meiotic telomere clustering", "d": ["The cell cycle process in which the dynamic reorganization of telomeres occurs in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. This plays an important role in progression through meiosis and precedes synapsis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072520", "l": "seminiferous tubule development", "d": ["The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120189", "l": "positive regulation of bile acid secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120140", "l": "negative regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902774", "l": "late endosome to lysosome transport", "d": ["The directed movement of substances from late endosome to lysosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120232", "l": "prenyl-FMNH2 biosynthetic process", "d": ["The chemical reactions and pathways resulting in prenyl-FMNH2, an essential cofactor for the decarboxylase enzymes UbiD and Fdc1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0050963", "l": "detection of electrical stimulus involved in sensory perception", "d": ["The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010825", "l": "positive regulation of centrosome duplication", "d": ["Any process that increases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030912", "l": "response to deep water", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a deep water stimulus, being immersed in standing deep water throughout the life cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0035898", "l": "parathyroid hormone secretion", "d": ["The regulated release of parathyroid hormone into the circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0033059", "l": "cellular pigmentation", "d": ["The deposition or aggregation of coloring matter in a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033072", "l": "vancomycin biosynthetic process", "d": ["The chemical reactions and pathways leading to the formation of vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010701", "l": "positive regulation of norepinephrine secretion", "d": ["Any process that increases the frequency, rate or extent of the regulated release of norepinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900840", "l": "regulation of helvolic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of helvolic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0045682", "l": "regulation of epidermis development", "d": ["Any process that modulates the frequency, rate or extent of epidermis development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090078", "l": "smooth muscle derived foam cell differentiation", "d": ["The process in which a smooth muscle cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0045003", "l": "double-strand break repair via synthesis-dependent strand annealing", "d": ["SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015676", "l": "vanadium ion transport", "d": ["The directed movement of vanadium (V) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0048753", "l": "pigment granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106212", "l": "centromere detachment from spindle pole body involved in meiotic chromosome organization", "d": ["The cell cycle process in which centromeres dissociate from the spindle pole body, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042334", "l": "taxis to electron acceptor", "d": ["The directed movement of a motile cell or organism in response to the presence of an alternative electron acceptor, for example, nitrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045173", "l": "O-sialoglycoprotein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of O-sialoglycoproteins, glycoproteins which contain sialic acid as one of their carbohydrates. They are often found on or in the cell or tissue membranes and participate in a variety of biological activities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903625", "l": "negative regulation of DNA catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903753", "l": "negative regulation of p38MAPK cascade", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of p38MAPK cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019854", "l": "L-ascorbic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000533", "l": "negative regulation of renal albumin absorption", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of renal albumin absorption."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0002327", "l": "immature B cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of an immature B cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071250", "l": "cellular response to nitrite", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045626", "l": "negative regulation of T-helper 1 cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900512", "l": "regulation of starch utilization system complex assembly", "d": ["Any process that modulates the frequency, rate or extent of starch utilization system complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0001892", "l": "embryonic placenta development", "d": ["The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "43.307178539799267", "identifiers": [{"i": "GO:0008283", "l": "cell population proliferation", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0050813", "l": "epothilone metabolic process", "d": ["The chemical reactions and pathways involving epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018357", "l": "protein-phycourobilin linkage via phycourobilin-bis-L-cysteine", "d": ["The linkage of the chromophore phycourobilin to phycoerythrins via phycourobilin-bis-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.990900157612501", "identifiers": [{"i": "GO:0016444", "l": "somatic cell DNA recombination", "d": ["Recombination occurring within or between DNA molecules in somatic cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039683", "l": "rolling circle double-stranded viral DNA replication", "d": ["A rolling circle viral DNA replication that begins with a double-stranded viral DNA genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036497", "l": "eIF2alpha dephosphorylation in response to endoplasmic reticulum stress", "d": ["The removal of a phosphate group from the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045655", "l": "regulation of monocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of monocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033510", "l": "luteolin metabolic process", "d": ["The chemical reactions and pathways involving luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090105", "l": "pancreatic E cell development", "d": ["The process whose specific outcome is the progression of a pancreatic E cell over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044813", "l": "glycolytic fermentation via PFOR pathway", "d": ["The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, continuing with pyruvate:ferredoxin oxidoreductase (PFOR) activity. This pathway is found in strict anaerobes such as Clostridia species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043627", "l": "response to estrogen", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1904350", "l": "regulation of protein catabolic process in the vacuole", "d": ["Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015869", "l": "protein-DNA complex transport", "d": ["The directed movement of protein-DNA complexes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070710", "l": "RNA uridine deletion", "d": ["The modification of an RNA molecule by removal of a uridine nucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097580", "l": "intracellular sequestering of copper ion", "d": ["The process of binding or confining copper ions in an intracellular area such that they are separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080149", "l": "sucrose induced translational repression", "d": ["Any process that stops, prevents or reduces the rate of translation as a result of increase in sucrose level."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006642", "l": "triglyceride mobilization", "d": ["The release of triglycerides, any triester of glycerol, from storage within cells or tissues, making them available for metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048147", "l": "negative regulation of fibroblast proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120245", "l": "terminal acetylenic compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048630", "l": "skeletal muscle tissue growth", "d": ["The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051897", "l": "positive regulation of protein kinase B signaling", "d": ["Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010621", "l": "negative regulation of transcription by transcription factor localization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0040022", "l": "feminization of hermaphroditic germ-line", "d": ["The determination of female sex and sexual phenotype in the germ-line of the hermaphrodite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035617", "l": "stress granule disassembly", "d": ["The disaggregation of a stress granule into its constituent protein and RNA parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904326", "l": "negative regulation of circadian sleep/wake cycle, wakefulness", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of circadian sleep/wake cycle, wakefulness."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045956", "l": "positive regulation of calcium ion-dependent exocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046833", "l": "positive regulation of RNA export from nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042139", "l": "early meiotic recombination nodule assembly", "d": ["During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during leptotene and zygotene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903111", "l": "negative regulation of single-strand break repair via homologous recombination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of single-strand break repair via homologous recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901405", "l": "negative regulation of tetrapyrrole catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061199", "l": "striated muscle contraction involved in embryonic body morphogenesis", "d": ["The process in which force is generated within striated embryonic muscle tissue, resulting in a contraction of the muscle that contributes to the formation of an embryo's characteristic body morphology."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022019", "l": "dorsal lateral ganglionic eminence cell proliferation", "d": ["The multiplication or reproduction of dorsal lateral ganglionic eminence cells, resulting in the expansion of the cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0001188", "l": "RNA polymerase I preinitiation complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase I promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905301", "l": "regulation of macropinocytosis", "d": ["Any process that modulates the frequency, rate or extent of macropinocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003395", "l": "neuron migration involved in dendrite retrograde extension", "d": ["The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904864", "l": "negative regulation of beta-catenin-TCF complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of beta-catenin-TCF complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034396", "l": "negative regulation of transcription from RNA polymerase II promoter in response to iron", "d": ["Any process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0033239", "l": "negative regulation of amine metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002912", "l": "negative regulation of lymphocyte anergy", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte anergy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0099540", "l": "trans-synaptic signaling by neuropeptide", "d": ["Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010774", "l": "meiotic strand invasion involved in reciprocal meiotic recombination", "d": ["The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032260", "l": "response to jasmonic acid stimulus involved in jasmonic acid and ethylene-dependent systemic resistance", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus received in the context of the jasmonic acid- and ethylene (ethene)-dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045681", "l": "positive regulation of R8 cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of R8 cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060189", "l": "positive regulation of protein desumoylation", "d": ["Any process that increases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0039020", "l": "pronephric nephron tubule development", "d": ["The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010365", "l": "positive regulation of ethylene biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of an ethylene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0019646", "l": "aerobic electron transport chain", "d": ["A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to oxygen to generate a transmembrane electrochemical gradient."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072325", "l": "vulval cell fate commitment", "d": ["The process in which the cellular identity of nematode vulval cells is acquired and determined. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044532", "l": "modulation of apoptotic process in another organism", "d": ["A process in which an organism modulates the frequency, rate or extent of apoptosis in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0099068", "l": "postsynapse assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a postsynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902338", "l": "negative regulation of apoptotic process involved in morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0002838", "l": "negative regulation of immune response to tumor cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune response to tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:2001222", "l": "regulation of neuron migration", "d": ["Any process that modulates the frequency, rate or extent of neuron migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0048486", "l": "parasympathetic nervous system development", "d": ["The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071108", "l": "protein K48-linked deubiquitination", "d": ["A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048689", "l": "formation of growth cone in injured axon", "d": ["The formation of a growth cone in an injured axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010100", "l": "negative regulation of photomorphogenesis", "d": ["Any process that stops, reduces or prevents photomorphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090444", "l": "regulation of nematode larval development, heterochronic", "d": ["Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and the rate at which this time point is reached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000694", "l": "regulation of phragmoplast microtubule organization", "d": ["Any process that modulates the frequency, rate or extent of phragmoplast microtubule organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.709828545597055", "identifiers": [{"i": "GO:0043043", "l": "peptide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.967140482697559", "identifiers": [{"i": "GO:0050921", "l": "positive regulation of chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900561", "l": "dehydroaustinol metabolic process", "d": ["The chemical reactions and pathways involving dehydroaustinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001768", "l": "establishment of T cell polarity", "d": ["The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044518", "l": "positive regulation of vasoactive intestinal polypeptide receptor activity in another organism", "d": ["A process that activates or increases the frequency, rate or extent of the activity of a vasoactive intestinal polypeptide receptor in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002733", "l": "regulation of myeloid dendritic cell cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010089", "l": "xylem development", "d": ["The formation of the principal water-conducting tissue of a vascular plant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.550902018460775", "identifiers": [{"i": "GO:0048589", "l": "developmental growth", "d": ["The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046580", "l": "negative regulation of Ras protein signal transduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050986", "l": "isopeptide cross-linking via N-(L-isoglutamyl)-glycine", "d": ["The formation of an isopeptide cross-link between peptidyl-glutamate and peptidyl-glycine to produce N-(L-isoglutamyl)-glycine, as found in the antibiotic microcin J25."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0008348", "l": "negative regulation of antimicrobial humoral response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an antimicrobial humoral response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070508", "l": "cholesterol import", "d": ["The directed movement of cholesterol into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0033047", "l": "regulation of mitotic sister chromatid segregation", "d": ["Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010258", "l": "NADH dehydrogenase complex (plastoquinone) assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form NADH:plastoquinone dehydrogenase complex, which is involved in the non-photochemical reduction of plastoquinones, as well as the cyclic electron transport around photosystem I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990212", "l": "positive regulation by symbiont of ethylene levels in host", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of the ethylene levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.892807203573966", "identifiers": [{"i": "GO:0009968", "l": "negative regulation of signal transduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0001913", "l": "T cell mediated cytotoxicity", "d": ["The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903479", "l": "mitotic actomyosin contractile ring assembly actin filament organization", "d": ["Any actin filament organization that is involved in mitotic actomyosin contractile ring assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035721", "l": "intraciliary retrograde transport", "d": ["The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098713", "l": "leucine import across plasma membrane", "d": ["The directed movement of leucine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044571", "l": "[2Fe-2S] cluster assembly", "d": ["The incorporation of two iron atoms and two sulfur atoms into an iron-sulfur cluster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990532", "l": "stress response to nickel ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a nickel ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000038", "l": "very long-chain fatty acid metabolic process", "d": ["The chemical reactions and pathways involving a very long chain fatty acid, a fatty acid with an aliphatic tail of 22 or more carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0036525", "l": "protein deglycation", "d": ["The removal of a sugar or dicarbonyl from a glycated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033132", "l": "negative regulation of glucokinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990194", "l": "cytoplasmic U snRNP body assembly", "d": ["The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic U snRNP body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032915", "l": "positive regulation of transforming growth factor beta2 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001826", "l": "inner cell mass cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010898", "l": "positive regulation of triglyceride catabolic process", "d": ["Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0099172", "l": "presynapse organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0044645", "l": "modulation of complement activation in another organism", "d": ["A process that modulates the frequency, rate or extent of complement activation in a different organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0042326", "l": "negative regulation of phosphorylation", "d": ["Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903001", "l": "negative regulation of lipid transport across blood-brain barrier", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lipid transport across blood-brain barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "45.740940351983859", "identifiers": [{"i": "GO:0044281", "l": "small molecule metabolic process", "d": ["The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0000028", "l": "ribosomal small subunit assembly", "d": ["The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0062036", "l": "sensory perception of hot stimulus", "d": ["The series of events required for an organism to receive a hot temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033351", "l": "UDP-D-apiose metabolic process", "d": ["The chemical reactions and pathways involving UDP-D-apiose, uridinediphosphoapiose, a substance composed of apiose in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903390", "l": "positive regulation of synaptic vesicle uncoating", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle uncoating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.669997983625713", "identifiers": [{"i": "GO:0006281", "l": "DNA repair", "d": ["The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905428", "l": "regulation of plant organ formation", "d": ["Any process that modulates the frequency, rate or extent of plant organ formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901628", "l": "positive regulation of postsynaptic membrane organization", "d": ["Any process that activates or increases the frequency, rate or extent of postsynaptic membrane organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052151", "l": "positive regulation by symbiont of host apoptotic process", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003088", "l": "positive regulation of the force of heart contraction by circulating epinephrine", "d": ["The process in which the secretion of epinephrine into the bloodstream modulates the force of heart muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160052", "l": "mitotic nuclear envelope segregation", "d": ["The mitotic cell cycle process in which the nuclear envelope, including nuclear pores, is equally distributed to the two daughter cells during the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000972", "l": "positive regulation of detection of glucose", "d": ["Any process that activates or increases the frequency, rate or extent of detection of glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090292", "l": "nuclear matrix anchoring at nuclear membrane", "d": ["The process in which the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane, is directly or indirectly linked to the nuclear membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905136", "l": "dethiobiotin import across plasma membrane", "d": ["The directed movement of dethiobiotin from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036091", "l": "positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010201", "l": "response to continuous far red light stimulus by the high-irradiance response system", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a continuous far red light stimulus by the high-irradiance response system. Far red light is electromagnetic radiation of wavelength 700-800nm. The activity of the high-irradiance response system is characterized by stronger effects of continuous than pulsed light at equal total fluence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018960", "l": "4-nitrophenol metabolic process", "d": ["The chemical reactions and pathways involving 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000296", "l": "negative regulation of hydrogen peroxide catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007282", "l": "cystoblast division", "d": ["Any of the rounds of incomplete mitosis undergone by a cystoblast to form a cyst of interconnected cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903697", "l": "negative regulation of microvillus assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051887", "l": "regulation of timing of exogen", "d": ["Any process that modulates the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071350", "l": "cellular response to interleukin-15", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002728", "l": "negative regulation of natural killer cell cytokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0045917", "l": "positive regulation of complement activation", "d": ["Any process that activates or increases the frequency, rate or extent of complement activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032692", "l": "negative regulation of interleukin-1 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1901900", "l": "regulation of protein localization to cell division site", "d": ["Any process that modulates the frequency, rate or extent of protein localization to cell division site."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0001845", "l": "phagolysosome assembly", "d": ["The process that results in the fusion of a phagosome, a vesicle formed by phagocytosis, with a lysosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.777964009505382", "identifiers": [{"i": "GO:0003205", "l": "cardiac chamber development", "d": ["The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0010976", "l": "positive regulation of neuron projection development", "d": ["Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035393", "l": "chemokine (C-X-C motif) ligand 9 production", "d": ["The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905463", "l": "negative regulation of DNA duplex unwinding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA duplex unwinding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0031340", "l": "positive regulation of vesicle fusion", "d": ["Any process that activates or increases the frequency, rate or extent of vesicle fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046151", "l": "eye pigment catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.892466024748572", "identifiers": [{"i": "GO:0007164", "l": "establishment of tissue polarity", "d": ["Coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042861", "l": "achromobactin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of achromobactin, a citrate siderophore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061931", "l": "positive regulation of erythrocyte enucleation", "d": ["Any process that increases the frequency, rate or extent of erythrocyte enucleation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.327400668044291", "identifiers": [{"i": "GO:0043271", "l": "negative regulation of monoatomic ion transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051729", "l": "germline cell cycle switching, mitotic to meiotic cell cycle", "d": ["The process in which a germline cell switches cell cycle mode from mitotic to meiotic division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900090", "l": "positive regulation of inositol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of inositol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140028", "l": "pore formation during contractile vacuole discharge", "d": ["The formation of a transient pore in the plasma membrane and the attached contractile vacuolar membrane, to release water from the cell. This process does not involve fusion of the two membranes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071491", "l": "cellular response to red light", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018886", "l": "anaerobic carbon tetrachloride metabolic process", "d": ["The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations, that occur in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0032292", "l": "peripheral nervous system axon ensheathment", "d": ["The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0070525", "l": "tRNA threonylcarbamoyladenosine metabolic process", "d": ["The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904116", "l": "response to vasopressin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006078", "l": "(1->6)-beta-D-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000827", "l": "mitochondrial RNA surveillance", "d": ["The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032725", "l": "positive regulation of granulocyte macrophage colony-stimulating factor production", "d": ["Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019704", "l": "peptidyl-L-cysteine S-myristoylation", "d": ["The modification of peptidyl-cysteine to form peptidyl-S-myristoyl-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900941", "l": "regulation of (Z)-nonadeca-1,14-diene biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010127", "l": "mycothiol-dependent detoxification", "d": ["The chemical reactions using mycothiol to convert an alkylating agent to an S-conjugate of mycothiol. The latter is cleaved to release mercapturic acid which is excreted from the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0044507", "l": "positive regulation of receptor activity in another organism", "d": ["A process that activates or increases the frequency, rate or extent of the activity of a receptor in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035572", "l": "N-terminal peptidyl-serine dimethylation", "d": ["The dimethylation of the N-terminal serine of proteins to form the derivative N,N-dimethylserine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0001956", "l": "positive regulation of neurotransmitter secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:1902931", "l": "negative regulation of alcohol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0015858", "l": "nucleoside transport", "d": ["The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120331", "l": "endothelial tube formation", "d": ["The developmental process pertaining to the initial formation of an endothelial tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061739", "l": "protein lipidation involved in autophagosome assembly", "d": ["The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the ATG8 family, leading to membrane insertion of the protein as a step in autophagosome assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021822", "l": "negative regulation of cell motility involved in cerebral cortex radial glia guided migration", "d": ["The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061817", "l": "endoplasmic reticulum-plasma membrane tethering", "d": ["The attachment of an endoplasmic reticulum membrane to the plasma membrane via molecular tethers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.608201942646453", "identifiers": [{"i": "GO:0097254", "l": "renal tubular secretion", "d": ["The elimination of substances from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046056", "l": "dADP metabolic process", "d": ["The chemical reactions and pathways involving dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015819", "l": "lysine transport", "d": ["The directed movement of lysine, 2,6-diaminohexanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900278", "l": "positive regulation of proteinase activated receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of proteinase activated receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019404", "l": "galactitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070798", "l": "positive regulation of cleistothecium development", "d": ["Any process that activates or increases the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900468", "l": "regulation of phosphatidylserine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylserine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032348", "l": "negative regulation of aldosterone biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071370", "l": "cellular response to gibberellin stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0002190", "l": "cap-independent translational initiation", "d": ["The process where translation initiation recruits the 40S ribosomal subunits in a Cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate mRNA or circRNA translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033259", "l": "plastid DNA replication", "d": ["The process in which new strands of DNA are synthesized in a plastid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097640", "l": "L-ornithine import across plasma membrane", "d": ["The directed movement of L-ornithine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0007142", "l": "male meiosis II", "d": ["A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043381", "l": "negative regulation of memory T cell differentiation", "d": ["Any process that stops, prevents, or reduces the rate of memory T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0009875", "l": "pollen-pistil interaction", "d": ["The interaction between a pollen grain and pistil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032097", "l": "positive regulation of response to food", "d": ["Any process that activates, maintains, or increases the rate of a response to a food stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021580", "l": "medulla oblongata formation", "d": ["The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904794", "l": "negative regulation of euchromatin binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of euchromatin binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033247", "l": "regulation of penicillin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0045488", "l": "pectin metabolic process", "d": ["The chemical reactions and pathways involving pectin, a group of galacturonic acid-containing, water-soluble colloidal carbohydrates of high molecular weight and of net negative charge."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002319", "l": "memory B cell differentiation", "d": ["The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071368", "l": "cellular response to cytokinin stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0090715", "l": "immunological memory formation process", "d": ["Any immunological memory process that can contribute to the formation of immunological memory."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042488", "l": "positive regulation of odontogenesis of dentin-containing tooth", "d": ["Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0034287", "l": "detection of monosaccharide stimulus", "d": ["The series of events in which a stimulus from a monosaccharide is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045796", "l": "negative regulation of intestinal cholesterol absorption", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0021680", "l": "cerebellar Purkinje cell layer development", "d": ["The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1990034", "l": "calcium ion export across plasma membrane", "d": ["The directed movement of calcium ions from inside of a cell, across the plasma membrane and into the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000340", "l": "positive regulation of chemokine (C-X-C motif) ligand 1 production", "d": ["Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904898", "l": "negative regulation of hepatic stellate cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036114", "l": "medium-chain fatty-acyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with an aliphatic tail of 6 to 12 carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904509", "l": "negative regulation of protein localization to basolateral plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to basolateral plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061296", "l": "negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis", "d": ["Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140048", "l": "manganese ion export across plasma membrane", "d": ["The directed movement of manganese ions from inside of a cell, across the plasma membrane and into the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051138", "l": "positive regulation of NK T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003061", "l": "positive regulation of the force of heart contraction by norepinephrine", "d": ["The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings modulates the force of heart musclecontraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902755", "l": "sulfurated eukaryotic molybdenum cofactor(2-) metabolic process", "d": ["The chemical reactions and pathways involving sulfurated eukaryotic molybdenum cofactor(2-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.644186068201407", "identifiers": [{"i": "GO:0050908", "l": "detection of light stimulus involved in visual perception", "d": ["The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902855", "l": "regulation of non-motile cilium assembly", "d": ["Any process that modulates the frequency, rate or extent of non-motile cilium assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006491", "l": "N-glycan processing", "d": ["The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061485", "l": "memory T cell proliferation", "d": ["The expansion of a memory T cell population by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048210", "l": "Golgi vesicle fusion to target membrane", "d": ["The joining of the lipid bilayer membrane around a Golgi transport vesicle to the target lipid bilayer membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0060317", "l": "cardiac epithelial to mesenchymal transition", "d": ["A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0085032", "l": "modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade", "d": ["Any process in which an organism modulates the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900144", "l": "positive regulation of BMP secretion", "d": ["Any process that activates or increases the frequency, rate or extent of BMP secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009640", "l": "photomorphogenesis", "d": ["The control of plant growth, development, and differentiation by the duration and nature of light, independent of photosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042702", "l": "uterine wall growth", "d": ["The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006248", "l": "CMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of CMP, cytidine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097437", "l": "maintenance of dormancy", "d": ["The dormancy process that results in an organism remaining in dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048575", "l": "short-day photoperiodism, flowering", "d": ["A change from vegetative to reproductive phase as a result of detection of, or exposure to, a period of light that falls short of the critical day length. The critical day length varies between species. Although the term is short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 minus the critical day length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140627", "l": "ubiquitin-dependent protein catabolic process via the C-end degron rule pathway", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the DesCEND (destruction via C-end degron) pathway. In the DesCEND pathway, C-terminal residues (C-end degrons) in substrates are recognized by Cul2-RING and Cul4-RING E3 ligases, whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation. C-end degrons can be present in full-length proteins, truncated proteins or proteolytically cleaved forms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000109", "l": "regulation of macrophage apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of macrophage apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903705", "l": "positive regulation of siRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of siRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0033005", "l": "positive regulation of mast cell activation", "d": ["Any process that activates or increases the frequency, rate, or extent of mast cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.961561335463053", "identifiers": [{"i": "GO:0071805", "l": "potassium ion transmembrane transport", "d": ["A process in which a potassium ion is transported from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140877", "l": "mevastatin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mevastatin , also known as compactin or ML-236B, and which acts as a potent competitive inhibitor of HMG-CoA reductase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060298", "l": "positive regulation of sarcomere organization", "d": ["Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0015736", "l": "hexuronate transmembrane transport", "d": ["The process in which hexuronate is transported across a lipid bilayer, from one side of a membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0003337", "l": "mesenchymal to epithelial transition involved in metanephros morphogenesis", "d": ["A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042305", "l": "specification of segmental identity, mandibular segment", "d": ["The specification of the characteristic structures of the mandibular segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048445", "l": "carpel morphogenesis", "d": ["The process in which the anatomical structures of the carpel are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0005986", "l": "sucrose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sucrose, the disaccharide fructofuranosyl-glucopyranoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0071265", "l": "L-methionine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048190", "l": "wing disc dorsal/ventral pattern formation", "d": ["The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046084", "l": "adenine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902772", "l": "positive regulation of phosphorelay signal transduction system involved in hydrogen peroxide mediated signaling pathway", "d": ["Any positive regulation of phosphorelay signal transduction system that is involved in hydrogen peroxide mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000391", "l": "positive regulation of neutrophil extravasation", "d": ["Any process that activates or increases the frequency, rate or extent of neutrophil extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030517", "l": "negative regulation of axon extension", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0030397", "l": "membrane disassembly", "d": ["The controlled breakdown of any cell membrane in the context of a normal process such as autophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072639", "l": "interleukin-33 production", "d": ["The appearance of interleukin-33 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0014743", "l": "regulation of muscle hypertrophy", "d": ["Any process that modulates the frequency, rate or extent of muscle hypertrophy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019454", "l": "L-cysteine catabolic process via cystine, using glutathione-cystine transhydrogenase", "d": ["The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme glutathione-cystine transhydrogenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090601", "l": "enucleation", "d": ["The process in which nucleated precursor cells lose their nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900225", "l": "regulation of NLRP3 inflammasome complex assembly", "d": ["Any process that modulates the frequency, rate or extent of NLRP3 inflammasome complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902159", "l": "regulation of cyclic nucleotide-gated ion channel activity", "d": ["Any process that modulates the frequency, rate or extent of cyclic nucleotide-gated ion channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.503963827996756", "identifiers": [{"i": "GO:0032200", "l": "telomere organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0015889", "l": "cobalamin transport", "d": ["The directed movement of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035981", "l": "tongue muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150024", "l": "oxidised low-density lipoprotein particle clearance", "d": ["The process in which an oxidised low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0071985", "l": "multivesicular body sorting pathway", "d": ["A vesicle-mediated transport process in which transmembrane proteins are ubiquitylated to facilitate their entry into luminal vesicles of multivesicular bodies (MVBs); upon subsequent fusion of MVBs with lysosomes or vacuoles, the cargo proteins are degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071334", "l": "cellular response to rhamnose stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0006868", "l": "glutamine transport", "d": ["The directed movement of glutamine, 2-amino-4-carbamoylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061606", "l": "N-terminal protein amino acid propionylation", "d": ["The propionylation of the N-terminal amino acid of proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0001996", "l": "positive regulation of heart rate by epinephrine-norepinephrine", "d": ["The process in which the presence of epinephrine or norepinephrine in the bloodstream activates, maintains or increases the rate of heart contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006241", "l": "CTP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CTP, cytidine 5'-triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032026", "l": "response to magnesium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.527781272052167", "identifiers": [{"i": "GO:0035051", "l": "cardiocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905002", "l": "positive regulation of membrane repolarization during atrial cardiac muscle cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033584", "l": "tyrosine biosynthetic process from chorismate via L-arogenate", "d": ["The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate L-arogenate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904650", "l": "negative regulation of fat cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010220", "l": "positive regulation of vernalization response", "d": ["Any process that activates or induces the rate of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015747", "l": "urate transport", "d": ["The directed movement of urate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0032814", "l": "regulation of natural killer cell activation", "d": ["Any process that modulates the frequency, rate or extent of natural killer cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0048937", "l": "lateral line nerve glial cell development", "d": ["The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904654", "l": "negative regulation of lung alveolus development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lung alveolus development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1901068", "l": "guanosine-containing compound metabolic process", "d": ["The chemical reactions and pathways involving guanosine-containing compounds (guanosines)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990051", "l": "activation of protein kinase C activity", "d": ["Any process that initiates the activity of the inactive enzyme protein kinase C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0042316", "l": "penicillin metabolic process", "d": ["The chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system. Penicillins are produced naturally during the growth of various microfungi of the genera Penicillium and Aspergillus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900447", "l": "regulation of cell morphogenesis involved in phenotypic switching", "d": ["Any process that modulates the frequency, rate or extent of cell morphogenesis contributing a phenotypic switch. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells, such as the opaque cells of C. albicans, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904828", "l": "positive regulation of hydrogen sulfide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of hydrogen sulfide biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010172", "l": "embryonic body morphogenesis", "d": ["The process in which the anatomical structures of the embryonic soma are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901931", "l": "alpha-copaene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alpha-copaene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0042723", "l": "thiamine-containing compound metabolic process", "d": ["The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903785", "l": "L-valine transmembrane transport", "d": ["The directed movement of L-valine across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051944", "l": "positive regulation of catecholamine uptake involved in synaptic transmission", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0009093", "l": "cysteine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cysteine, 2-amino-3-mercaptopropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008335", "l": "female germline ring canal stabilization", "d": ["Maintenance of the structural integrity of the ring canals connecting the female germline cyst."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0016266", "l": "O-glycan processing", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form a core O-glycan structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019698", "l": "D-galacturonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018290", "l": "iron and molybdenum incorporation into iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide", "d": ["The incorporation of iron and molybdenum into a Mo-7Fe-8S iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide, found in nitrogenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902043", "l": "positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "d": ["Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098910", "l": "regulation of atrial cardiac muscle cell action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrial cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0000266", "l": "mitochondrial fission", "d": ["The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0006691", "l": "leukotriene metabolic process", "d": ["The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990502", "l": "dense core granule maturation", "d": ["Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0062084", "l": "regulation of capsule polysaccharide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.50898652134218", "identifiers": [{"i": "GO:0035825", "l": "homologous recombination", "d": ["A DNA recombination process that results in the exchange of an equal amount of genetic material between highly homologous DNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033253", "l": "regulation of penicillinase activity", "d": ["Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of a penicillin to yield a substituted beta-amino acid derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0010413", "l": "glucuronoxylan metabolic process", "d": ["The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid side units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000455", "l": "regulation of T-helper 17 cell extravasation", "d": ["Any process that modulates the frequency, rate or extent of T-helper 17 cell extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106108", "l": "negative regulation of (R)-mevalonic acid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of (R)-mevalonic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.468544520863134", "identifiers": [{"i": "GO:0009994", "l": "oocyte differentiation", "d": ["The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097410", "l": "hippocampal interneuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a hippocampal interneuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904130", "l": "regulation of convergent extension involved in neural plate elongation", "d": ["Any process that modulates the frequency, rate or extent of convergent extension involved in neural plate elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006196", "l": "AMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of AMP, adenosine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902381", "l": "11-oxo-beta-amyrin metabolic process", "d": ["The chemical reactions and pathways involving 11-oxo-beta-amyrin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000620", "l": "positive regulation of histone H4-K16 acetylation", "d": ["Any process that activates or increases the frequency, rate or extent of histone H4-K16 acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901842", "l": "negative regulation of high voltage-gated calcium channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of high voltage-gated calcium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060718", "l": "chorionic trophoblast cell differentiation", "d": ["The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097498", "l": "endothelial tube lumen extension", "d": ["Any endothelial tube morphogenesis process by which the tube is increased in length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051333", "l": "meiotic nuclear membrane reassembly", "d": ["The cell cycle process in which the reformation of the nuclear membranes during meiosis occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.468544520863134", "identifiers": [{"i": "GO:0035461", "l": "vitamin transmembrane transport", "d": ["The process in which a vitamin is transported across a membrane. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032802", "l": "low-density lipoprotein particle receptor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0009408", "l": "response to heat", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904615", "l": "cellular response to biphenyl", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1900048", "l": "positive regulation of hemostasis", "d": ["Any process that activates or increases the frequency, rate or extent of hemostasis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090331", "l": "negative regulation of platelet aggregation", "d": ["Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072299", "l": "negative regulation of metanephric glomerulus development", "d": ["Any process that decreases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003060", "l": "negative regulation of the force of heart contraction by acetylcholine", "d": ["The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors and decreases the force of heart muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035863", "l": "dITP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dITP, a deoxyinosine phosphate compound having a triphosphate group at the 5'-position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099157", "l": "trans-synaptic signalling via exosome", "d": ["Transynaptic signaling in which the ligand is carried across the synapse by an exosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039018", "l": "nephrostome development", "d": ["The process whose specific outcome is the progression of the nephrostome over time, from its formation to the mature structure. The nephrostome is the opening of the pronephros into the body cavity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900843", "l": "regulation of monodictyphenone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of monodictyphenone biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097548", "l": "seed abscission", "d": ["The controlled shedding of a seed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0071786", "l": "endoplasmic reticulum tubular network organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904510", "l": "positive regulation of protein localization to basolateral plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to basolateral plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0089707", "l": "L-lysine transmembrane export from vacuole", "d": ["The directed movement of L-lysine out of the vacuole, across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0070591", "l": "ascospore wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of an ascospore wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0044070", "l": "regulation of monoatomic anion transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0006110", "l": "regulation of glycolytic process", "d": ["Any process that modulates the frequency, rate or extent of glycolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046436", "l": "D-alanine metabolic process", "d": ["The chemical reactions and pathways involving D-alanine, the D-enantiomer of the amino acid alanine, i.e. (2R)-2-aminopropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0042249", "l": "establishment of planar polarity of embryonic epithelium", "d": ["Coordinated organization of groups of cells in the plane of an embryonic epithelium, such that they all orient to similar coordinates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010949", "l": "negative regulation of intestinal phytosterol absorption", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of phytosterols into the blood by absorption from the small intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051396", "l": "positive regulation of nerve growth factor receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904332", "l": "negative regulation of error-prone translesion synthesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of error-prone translesion synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071691", "l": "cardiac muscle thin filament assembly", "d": ["The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in cardiac muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046516", "l": "hypusine metabolic process", "d": ["The chemical reactions and pathways involving hypusine, N6-(4-amino-2-hydroxybutyl)-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014863", "l": "detection of inactivity", "d": ["The series of events in which a inactivity stimulus is received by a cell or organism and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.905555711669919", "identifiers": [{"i": "GO:0002089", "l": "lens morphogenesis in camera-type eye", "d": ["The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021906", "l": "hindbrain-spinal cord boundary formation", "d": ["The process whose specific outcome is the formation of the hindbrain-spinal cord boundary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.415767841334464", "identifiers": [{"i": "GO:0044550", "l": "secondary metabolite biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901732", "l": "quercetin metabolic process", "d": ["The chemical reactions and pathways involving quercetin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904986", "l": "positive regulation of quinolinate biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of quinolinate biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036039", "l": "curcumin metabolic process", "d": ["The chemical reactions and pathways involving the polyphenol, curcumin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003046", "l": "regulation of systemic arterial blood pressure by stress relaxation", "d": ["The intrinsic circulatory process resulting from stress relaxation that modulates the force with which blood travels through the systemic arterial circulatory system. Stress relaxation is the adaptation of vessels to a new size as a result of changes in pressure in storage areas such as veins, the liver, the spleen, and the lungs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905903", "l": "negative regulation of mesoderm formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097717", "l": "copper ion transport across blood-cerebrospinal fluid barrier", "d": ["The directed movement of copper (Cu) ions passing through the blood-cerebrospinal fluid barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0090657", "l": "telomeric loop disassembly", "d": ["The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0120032", "l": "regulation of plasma membrane bounded cell projection assembly", "d": ["Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905261", "l": "regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination", "d": ["Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.655739316124155", "identifiers": [{"i": "GO:0042063", "l": "gliogenesis", "d": ["The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002543", "l": "activation of blood coagulation via clotting cascade", "d": ["Any process that initiates the clotting cascade of blood coagulation, a cascade of plasma enzymes that is triggered following damage to blood vessels, leading to formation of a clot."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048235", "l": "pollen sperm cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a haploid sperm cell within the plant gametophyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042778", "l": "tRNA end turnover", "d": ["The process in which the 3'-terminal CCA of a tRNA is removed and restored. This often happens to uncharged tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106114", "l": "regulation of mitotic cohesin dsDNA (leading strand) loading", "d": ["Any process that modulates the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990564", "l": "protein polyufmylation", "d": ["Covalent attachment of the ubiquitin-like protein UFM1 to a protein, forming an UFM1 chain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070428", "l": "regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0006500", "l": "N-terminal protein palmitoylation", "d": ["The covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000443", "l": "regulation of toll-like receptor 21 signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of toll-like receptor 21 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000316", "l": "sulfite transport", "d": ["The directed movement of sulfite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048065", "l": "male courtship behavior, veined wing extension", "d": ["The process during courtship where the male insect extends his wings. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036522", "l": "negative regulation by symbiont of host protein localization to phagocytic vesicle", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:0009404", "l": "toxin metabolic process", "d": ["The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903804", "l": "glycine import across plasma membrane", "d": ["The directed movement of glycine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090630", "l": "activation of GTPase activity", "d": ["Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905900", "l": "negative regulation of smooth muscle tissue development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902251", "l": "negative regulation of erythrocyte apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045630", "l": "positive regulation of T-helper 2 cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.125053100897617", "identifiers": [{"i": "GO:0001822", "l": "kidney development", "d": ["The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000274", "l": "regulation of epithelial cell migration, open tracheal system", "d": ["Any process that modulates the frequency, rate or extent of epithelial cell migration, open tracheal system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0034350", "l": "regulation of glial cell apoptotic process", "d": ["Any process that modulates the frequency, rate, or extent of glial cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905083", "l": "negative regulation of mitochondrial translational elongation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial translational elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990830", "l": "cellular response to leukemia inhibitory factor", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071769", "l": "mycolate cell wall layer assembly", "d": ["The aggregation, arrangement and bonding together of a set of components, including arabinogalactan mycolate and trehalose dimycolate, to form the mycolate layer of the Actinobacterium-type cell wall. The mycolate layer is physically attached to the peptidoglycan layer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900661", "l": "regulation of emericellamide A biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of emericellamide A biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010409", "l": "extensin metabolic process", "d": ["The chemical reactions and pathways involving extensins, a group of 60-90 kDNA hydroxyproline (Hyp)-rich glycoproteins whose polypeptide backbone consists of many repeats of structural Ser(Hyp)4-6 motifs, with heavily glycosylated 1-4 arabinose residues O-linked to contiguous stretches of Hyp residues, with most of the Ser residues being O-galactosylated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990555", "l": "mitochondrial oxaloacetate transmembrane transport", "d": ["The process in which oxaloacetate is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0043687", "l": "post-translational protein modification", "d": ["The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1903573", "l": "negative regulation of response to endoplasmic reticulum stress", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0101024", "l": "mitotic nuclear membrane organization", "d": ["A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.154928939654667", "identifiers": [{"i": "GO:0006661", "l": "phosphatidylinositol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061754", "l": "negative regulation of circulating fibrinogen levels", "d": ["Any process that reduces the quantity of fibrinogen circulating in the bloodstream."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051892", "l": "negative regulation of cardioblast differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000704", "l": "positive regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation", "d": ["Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1902743", "l": "regulation of lamellipodium organization", "d": ["Any process that modulates the frequency, rate or extent of lamellipodium organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.139845358389962", "identifiers": [{"i": "GO:0090068", "l": "positive regulation of cell cycle process", "d": ["Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904311", "l": "response to gold(3+)", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0051630", "l": "acetylcholine uptake", "d": ["The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0034772", "l": "histone H4-K20 dimethylation", "d": ["The modification of histone H4 by addition of two methyl groups to lysine at position 20 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901759", "l": "beta-L-Ara4N-lipid A metabolic process", "d": ["The chemical reactions and pathways involving beta-L-Ara4N-lipid A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0048619", "l": "embryonic hindgut morphogenesis", "d": ["The process in which the anatomical structures of the hindgut are generated and organized, during the embryonic phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0098712", "l": "L-glutamate import across plasma membrane", "d": ["The directed movement of L-glutamate from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0033484", "l": "intracellular nitric oxide homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of nitric oxide within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905503", "l": "regulation of motile cilium assembly", "d": ["Any process that modulates the frequency, rate or extent of motile cilium assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034163", "l": "regulation of toll-like receptor 9 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 9 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070503", "l": "selenium-containing prosthetic group metabolic process", "d": ["The chemical reactions and pathways involving a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904755", "l": "regulation of gut granule assembly", "d": ["Any process that modulates the frequency, rate or extent of gut granule assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0006862", "l": "nucleotide transport", "d": ["The directed movement of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, into, out of or within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060575", "l": "intestinal epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1901219", "l": "regulation of cardiac chamber morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900863", "l": "positive regulation of cordyol C biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of cordyol C biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900981", "l": "negative regulation of phenazine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phenazine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032470", "l": "positive regulation of endoplasmic reticulum calcium ion concentration", "d": ["Any process that increases the concentration of calcium ions in the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.788903440275099", "identifiers": [{"i": "GO:0072001", "l": "renal system development", "d": ["The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0110053", "l": "regulation of actin filament organization", "d": ["Any process that modulates the frequency, rate or extent of actin filament organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009801", "l": "cinnamic acid ester metabolic process", "d": ["The chemical reactions and pathways involving ester derivatives of cinnamic acid, phenylpropenoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071366", "l": "cellular response to indolebutyric acid stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.250759876326711", "identifiers": [{"i": "GO:0002700", "l": "regulation of production of molecular mediator of immune response", "d": ["Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1901890", "l": "positive regulation of cell junction assembly", "d": ["Any process that activates or increases the frequency, rate or extent of cell junction assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044874", "l": "lipoprotein localization to outer membrane", "d": ["A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905053", "l": "positive regulation of base-excision repair", "d": ["Any process that activates or increases the frequency, rate or extent of base-excision repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.72235522081229", "identifiers": [{"i": "GO:1903047", "l": "mitotic cell cycle process", "d": ["A process that is part of the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0098901", "l": "regulation of cardiac muscle cell action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904751", "l": "positive regulation of protein localization to nucleolus", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072227", "l": "metanephric macula densa development", "d": ["The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036235", "l": "acyl deglucuronidation", "d": ["The removal of glucuronic acid from an acyl-glucuronide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:1901376", "l": "organic heteropentacyclic compound metabolic process", "d": ["The chemical reactions and pathways involving organic heteropentacyclic compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000540", "l": "negative regulation of protein geranylgeranylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein geranylgeranylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905389", "l": "response to leukotriene B4", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0006700", "l": "C21-steroid hormone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.664775500092716", "identifiers": [{"i": "GO:0051180", "l": "vitamin transport", "d": ["The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000712", "l": "regulation of maintenance of meiotic sister chromatid cohesion, arms", "d": ["Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902261", "l": "positive regulation of delayed rectifier potassium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of delayed rectifier potassium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035711", "l": "T-helper 1 cell activation", "d": ["The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002466", "l": "peripheral tolerance induction to self antigen", "d": ["Tolerance induction to self antigens in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000503", "l": "positive regulation of natural killer cell chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0061097", "l": "regulation of protein tyrosine kinase activity", "d": ["Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0051323", "l": "metaphase", "d": ["The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052064", "l": "induction by symbiont of defense-related host reactive oxygen species production", "d": ["The activation by a symbiont of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000362", "l": "negative regulation of prostaglandin-E synthase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin-E synthase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019990", "l": "pteridine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003245", "l": "cardiac muscle tissue growth involved in heart morphogenesis", "d": ["The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033659", "l": "modification by symbiont of host mitochondrion", "d": ["The process in which an organism effects a change in the structure or function of host cell mitochondria. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048939", "l": "anterior lateral line nerve glial cell development", "d": ["The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033521", "l": "phytyl diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0070278", "l": "extracellular matrix constituent secretion", "d": ["The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035855", "l": "megakaryocyte development", "d": ["The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033660", "l": "suppression by symbiont of host resistance gene-dependent defense response", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043930", "l": "primary ovarian follicle growth involved in primary follicle stage", "d": ["Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle) as part of the primary follicle stage of oogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900086", "l": "positive regulation of peptidyl-tyrosine autophosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of peptidyl-tyrosine autophosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.240853996207278", "identifiers": [{"i": "GO:0050892", "l": "intestinal absorption", "d": ["Any process in which nutrients are taken up from the contents of the intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.465174152298118", "identifiers": [{"i": "GO:0044409", "l": "entry into host", "d": ["Entry of a symbiont into the body, tissues, or cells of a host organism as part of the symbiont life cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000948", "l": "amino acid catabolic process to carboxylic acid via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1990840", "l": "response to lectin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032672", "l": "regulation of interleukin-3 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-3 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015707", "l": "nitrite transport", "d": ["The directed movement of nitrite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0062043", "l": "positive regulation of cardiac epithelial to mesenchymal transition", "d": ["Any process that starts or increases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061402", "l": "positive regulation of transcription from RNA polymerase II promoter in response to acidic pH", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH stimulus with pH < 7."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080110", "l": "sporopollenin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sporopollenin, a primary constituent of the pollen exine layer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021519", "l": "spinal cord association neuron specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an association neuron in an environment that is neutral with respect to the developmental pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031643", "l": "positive regulation of myelination", "d": ["Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061222", "l": "mesonephric mesenchymal cell proliferation involved in mesonephros development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a mesonephric mesenchymal cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035760", "l": "cytoplasmic polyadenylation-dependent rRNA catabolic process", "d": ["The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070810", "l": "positive regulation of Hulle cell development", "d": ["Any process that activates or increases the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1904892", "l": "regulation of receptor signaling pathway via STAT", "d": ["Any process that modulates the frequency, rate or extent of receptor signaling via STAT."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046284", "l": "anthocyanin-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014914", "l": "myoblast maturation involved in muscle regeneration", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast cell to attain its fully functional state involved in muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904977", "l": "lymphatic endothelial cell migration", "d": ["The orderly movement of a lymphatic endothelial cell from one site to another in the wall of a lymphatic vessel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905307", "l": "response to miconazole", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0000154", "l": "rRNA modification", "d": ["The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0000462", "l": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0035308", "l": "negative regulation of protein dephosphorylation", "d": ["Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905032", "l": "negative regulation of membrane repolarization during cardiac muscle cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002498", "l": "proteolysis within endoplasmic reticulum associated with antigen processing and presentation", "d": ["The hydrolysis of a peptide bond or bonds within a protein by ER resident proteases contributing to antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036059", "l": "nephrocyte diaphragm assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a nephrocyte diaphragm, a specialized cell-cell junction found between nephrocytes of the insect kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000646", "l": "positive regulation of receptor catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of receptor catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009302", "l": "sno(s)RNA transcription", "d": ["The synthesis of snoRNA class RNA (also referred to as sRNA in Archaea) from a DNA template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0046122", "l": "purine deoxyribonucleoside metabolic process", "d": ["The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.873618708841299", "identifiers": [{"i": "GO:0009612", "l": "response to mechanical stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090237", "l": "regulation of arachidonic acid secretion", "d": ["Any process that modulates the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0098698", "l": "postsynaptic specialization assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "51.683474935761744", "identifiers": [{"i": "GO:0032879", "l": "regulation of localization", "d": ["Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090597", "l": "nematode male tail mating organ morphogenesis", "d": ["The process in which the anatomical structures of the nematode male tail mating organ are generated and organized. The male tail is a sensory organ required for mating and, in C. elegans, consists of ray sensilla, an acellular cuticular fan, a sensory hook, and protracting, copulatory spicules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0072655", "l": "establishment of protein localization to mitochondrion", "d": ["The directed movement of a protein to the mitochondrion or a part of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0048200", "l": "Golgi transport vesicle coating", "d": ["The addition of specific coat proteins to Golgi membranes during the formation of transport vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0071222", "l": "cellular response to lipopolysaccharide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052889", "l": "9,9'-di-cis-zeta-carotene desaturation to 7,9,7',9'-tetra-cis-lycopene", "d": ["The series of reactions in which 9,9'-di-cis-zeta-carotene is desaturated to 7,9,9'-tri-cis-neurosporene, and then 7,9,7',9'-tetra-cis-lycopene. The overall reaction for this process is: 9,9'-di-cis-zeta-carotene + 2 quinone = 2 quinol + 7,9,7',9'-tetra-cis-lycopene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0042661", "l": "regulation of mesodermal cell fate specification", "d": ["Any process that modulates the frequency, rate or extent of mesoderm cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0000023", "l": "maltose metabolic process", "d": ["The chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015628", "l": "protein secretion by the type II secretion system", "d": ["The process in which proteins are secreted across the outer membrane of Gram-negative bacteria by the type II secretion system. Proteins using this pathway are first translocated across the cytoplasmic membrane via the Sec or Tat pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046370", "l": "fructose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fructose, the ketohexose arabino-2-hexulose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033472", "l": "GDP-L-galactose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0052317", "l": "camalexin metabolic process", "d": ["The chemical reactions and pathways involving camalexin, an indole phytoalexin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048396", "l": "negative regulation of intermediate mesodermal cell fate determination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000018", "l": "regulation of male gonad development", "d": ["Any process that modulates the frequency, rate or extent of male gonad development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032706", "l": "negative regulation of interleukin-22 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-22 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902049", "l": "neosartoricin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of neosartoricin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062087", "l": "positive regulation of vein smooth muscle contraction", "d": ["Any process that increases the frequency, rate or extent of vein smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1901475", "l": "pyruvate transmembrane transport", "d": ["The directed movement of pyruvate across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061075", "l": "positive regulation of neural retina development", "d": ["Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052160", "l": "modulation by symbiont of host systemic acquired resistance", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1904729", "l": "regulation of intestinal lipid absorption", "d": ["Any process that modulates the frequency, rate or extent of intestinal lipid absorption."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.362525179576039", "identifiers": [{"i": "GO:0060173", "l": "limb development", "d": ["The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080191", "l": "secondary thickening", "d": ["Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of tissue from a secondary thickening meristem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033520", "l": "phytol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0003417", "l": "growth plate cartilage development", "d": ["The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060455", "l": "negative regulation of gastric acid secretion", "d": ["Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000774", "l": "positive regulation of cellular senescence", "d": ["Any process that activates or increases the frequency, rate or extent of cellular senescence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2001100", "l": "pentasaccharide transport", "d": ["The directed movement of a pentasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036518", "l": "chemorepulsion of dopaminergic neuron axon", "d": ["The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0032094", "l": "response to food", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043579", "l": "elaioplast organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an elaioplast, a leucoplast in which oil is stored."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0000080", "l": "mitotic G1 phase", "d": ["The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043969", "l": "histone H2B acetylation", "d": ["The modification of histone H2B by the addition of an acetyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075306", "l": "regulation of conidium formation", "d": ["Any process that modulates the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0010112", "l": "regulation of systemic acquired resistance", "d": ["Any process that modulates the frequency, rate or extent of systemic acquired resistance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0014043", "l": "negative regulation of neuron maturation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0033152", "l": "immunoglobulin V(D)J recombination", "d": ["The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042076", "l": "protein phosphate-linked glycosylation", "d": ["The glycosylation of peptidyl-amino acids through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035011", "l": "melanotic encapsulation of foreign target", "d": ["Formation of a multilayered, melanized sheath of cells around a foreign invader."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032150", "l": "ubiquinone biosynthetic process from chorismate", "d": ["The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061913", "l": "positive regulation of growth plate cartilage chondrocyte proliferation", "d": ["Any process that increases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905298", "l": "regulation of intestinal epithelial cell development", "d": ["Any process that modulates the frequency, rate or extent of intestinal epithelial cell development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043573", "l": "leucoplast fission", "d": ["The creation of two or more leucoplasts by division of one leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021900", "l": "ventricular zone cell fate commitment", "d": ["The commitment of neuroblast to become a basal progenitor cell. Basal progenitor cells are neuronal precursor cells that are committed to becoming neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071301", "l": "cellular response to vitamin B1", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099140", "l": "presynaptic actin cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110147", "l": "protein maturation by nickel ion transfer", "d": ["A process that contributes to the delivery of nickel ions to a target protein to facilitate its maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035741", "l": "activated CD4-positive, alpha-beta T cell proliferation", "d": ["The expansion of an activated CD4-positive, alpha-beta T cell population by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904884", "l": "positive regulation of telomerase catalytic core complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of telomerase catalytic core complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019085", "l": "early viral transcription", "d": ["The first phase of viral transcription that occurs after entry of the virus into the host cell, but prior to viral genome replication. It involves the transcription of genes for non-structural proteins, and for lytic viruses, the early gene products are involved in establishing control over the host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032685", "l": "negative regulation of granulocyte macrophage colony-stimulating factor production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903045", "l": "neural crest cell migration involved in sympathetic nervous system development", "d": ["Any neural crest cell migration that is involved in sympathetic nervous system development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009270", "l": "response to humidity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905315", "l": "cell proliferation involved in endocardial cushion morphogenesis", "d": ["Any cell proliferation that is involved in endocardial cushion morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048765", "l": "root hair cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a root hair cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990506", "l": "mitotic DNA-templated DNA replication", "d": ["A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands during the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006154", "l": "adenosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904969", "l": "slow muscle cell migration", "d": ["The orderly movement of a slow muscle cell from one site to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070350", "l": "regulation of white fat cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of white fat cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905792", "l": "positive regulation of mechanosensory behavior", "d": ["Any process that activates or increases the frequency, rate or extent of mechanosensory behavior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901684", "l": "arsenate ion transmembrane transport", "d": ["The process in which arsenate is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0018023", "l": "peptidyl-lysine trimethylation", "d": ["The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990874", "l": "vascular associated smooth muscle cell proliferation", "d": ["The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106384", "l": "dGMP salvage", "d": ["Any process which produces a dGMP from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.357413409522593", "identifiers": [{"i": "GO:0061919", "l": "process utilizing autophagic mechanism", "d": ["A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061363", "l": "negative regulation of progesterone biosynthesis involved in luteolysis", "d": ["Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000495", "l": "regulation of cell proliferation involved in compound eye morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033533", "l": "verbascose metabolic process", "d": ["The chemical reactions and pathways involving verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140251", "l": "regulation protein catabolic process at presynapse", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051125", "l": "regulation of actin nucleation", "d": ["Any process that modulates the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010097", "l": "specification of stamen identity", "d": ["The process in which a floral organ primordium acquires stamen or staminode identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0046246", "l": "terpene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of terpenes, any of a large group of hydrocarbons made up of isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.207992593949683", "identifiers": [{"i": "GO:0007015", "l": "actin filament organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034230", "l": "enkephalin processing", "d": ["The formation of mature enkephalin, a pentapeptide hormone involved in regulating pain and nociception in the body by proteolytic processing of enkephalin propeptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000612", "l": "regulation of thyroid-stimulating hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of thyroid-stimulating hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.295828638494967", "identifiers": [{"i": "GO:0022613", "l": "ribonucleoprotein complex biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070846", "l": "Hsp90 deacetylation", "d": ["The modification of an Hsp90 protein by removal of acetyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018419", "l": "protein catenane formation", "d": ["The aggregation, arrangement and bonding together of a protein structure comprising two or more rings that are interlocked but not covalently joined; resembling the links of a chain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0016358", "l": "dendrite development", "d": ["The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900701", "l": "regulation of orcinol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of orcinol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902190", "l": "2-methylbutanoyl-CoA(4-) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-methylbutanoyl-CoA(4-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0101017", "l": "regulation of mitotic DNA replication initiation from late origin", "d": ["Any process that modulates the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.644186068201407", "identifiers": [{"i": "GO:0051650", "l": "establishment of vesicle localization", "d": ["The directed movement of a vesicle to a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048321", "l": "axial mesodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an axial mesoderm cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903325", "l": "positive regulation of snoRNA metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of snoRNA metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042075", "l": "nickel incorporation into nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide", "d": ["The incorporation of nickel into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071892", "l": "thrombocyte activation", "d": ["A cell activation process that occurs in thrombocytes and consists of a series of progressive, overlapping events including shape change, adhesiveness, and aggregation, which, when carried through to completion, lead to the formation of a stable hemostatic plug. Thrombocytes are nucleated cells found in non-mammalian vertebrates and are involved in hemostasis. They are the functional equivalent of the non-nucleated platelets found in mammals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903937", "l": "response to acrylamide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0033079", "l": "immature T cell proliferation", "d": ["The expansion of an immature T cell population by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048296", "l": "regulation of isotype switching to IgA isotypes", "d": ["Any process that modulates the frequency, rate or extent of isotype switching to IgA isotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010215", "l": "cellulose microfibril organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellulose microfibril, any of the cellulose structures laid down in orthogonal layers in a plant cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0015986", "l": "proton motive force-driven ATP synthesis", "d": ["The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021792", "l": "chemoattraction of branchiomotor axon", "d": ["The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to an attractive chemical signal. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000355", "l": "negative regulation of ovarian follicle development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.777964009505382", "identifiers": [{"i": "GO:0019218", "l": "regulation of steroid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099014", "l": "neuronal dense core vesicle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002084", "l": "protein depalmitoylation", "d": ["The removal of palymitoyl groups from a lipoprotein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0071489", "l": "cellular response to red or far red light", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015670", "l": "carbon dioxide transport", "d": ["The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.261443428098588", "identifiers": [{"i": "GO:0018027", "l": "peptidyl-lysine dimethylation", "d": ["The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034696", "l": "response to prostaglandin F", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009243", "l": "O antigen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905087", "l": "positive regulation of bioluminescence", "d": ["Any process that activates or increases the frequency, rate or extent of bioluminescence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009149", "l": "pyrimidine nucleoside triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033586", "l": "L-phenylalanine biosynthetic process from chorismate via L-arogenate", "d": ["The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate L-arogenate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019756", "l": "cyanogenic glycoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042121", "l": "alginic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0098722", "l": "asymmetric stem cell division", "d": ["Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.759446066112609", "identifiers": [{"i": "GO:0008202", "l": "steroid metabolic process", "d": ["The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0120261", "l": "regulation of heterochromatin organization", "d": ["Any process that modulates the frequency, rate, extent or location of heterochromatin organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.825466069370655", "identifiers": [{"i": "GO:0050863", "l": "regulation of T cell activation", "d": ["Any process that modulates the frequency, rate or extent of T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075321", "l": "oomycete sporangium development", "d": ["The process that leads to the development of an oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiates, through specialized cleavage vesicles, into between 10 and 30 zoospores, which are laterally flagellated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0006548", "l": "histidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0051101", "l": "regulation of DNA binding", "d": ["Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0000365", "l": "mRNA trans splicing, via spliceosome", "d": ["The joining together of exons from two different primary transcripts of messenger RNA (mRNA) via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003218", "l": "cardiac left ventricle formation", "d": ["The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0014805", "l": "smooth muscle adaptation", "d": ["Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901957", "l": "regulation of cutin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of cutin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.235181147905195", "identifiers": [{"i": "GO:1901988", "l": "negative regulation of cell cycle phase transition", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle phase transition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045463", "l": "R8 cell development", "d": ["The process whose specific outcome is the progression of the R8 photoreceptor over time, from its formation to the mature structure. The R8 photoreceptor is the founding receptor of each ommatidium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018928", "l": "methyl ethyl ketone metabolic process", "d": ["The chemical reactions and pathways involving methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor. It is used as a solvent and in making plastics, textiles and paints."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120074", "l": "regulation of endocardial cushion cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of cell differentiation, the process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009556", "l": "microsporogenesis", "d": ["The process in which the microsporocyte undergoes meiosis, giving rise to four haploid microspores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0009048", "l": "dosage compensation by inactivation of X chromosome", "d": ["Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901053", "l": "sarcosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sarcosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060406", "l": "positive regulation of penile erection", "d": ["Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036492", "l": "eiF2alpha phosphorylation in response to endoplasmic reticulum stress", "d": ["The addition of a phosphate group on to the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000315", "l": "positive regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation", "d": ["Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902309", "l": "negative regulation of peptidyl-serine dephosphorylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-serine dephosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903092", "l": "pyridoxine transmembrane transport", "d": ["The process in which pyridoxine is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090454", "l": "glutamate transmembrane import into vacuole", "d": ["The directed movement of glutamate into the vacuole across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1900785", "l": "naphtho-gamma-pyrone metabolic process", "d": ["The chemical reactions and pathways involving naphtho-gamma-pyrone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900677", "l": "positive regulation of F-9775B biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of F-9775B biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051137", "l": "negative regulation of NK T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014872", "l": "myoblast division", "d": ["The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:1904688", "l": "regulation of cytoplasmic translational initiation", "d": ["Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "37.187250934096141", "identifiers": [{"i": "GO:0035148", "l": "tube formation", "d": ["Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106402", "l": "Lewis x epitope biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a Lewis x epitope, a trisaccharide (beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-beta-D-glucosamine) expressed on several glycolipids, glycoproteins, and proteoglycans of the nervous system. The related Lewis x epitope is formed by alpha(1,3) fucosylation of the N-acetylglucosaminyl residue of a type 2 histo-blood group antigen precursor disaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002783", "l": "antifungal peptide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an antifungal peptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002588", "l": "positive regulation of antigen processing and presentation of peptide antigen via MHC class II", "d": ["Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0072683", "l": "T cell extravasation", "d": ["The migration of a T cell from the blood vessels into the surrounding tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002371", "l": "dendritic cell cytokine production", "d": ["Any process that contributes to cytokine production by a dendritic cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035571", "l": "N-terminal peptidyl-serine monomethylation", "d": ["The monomethylation of the N-terminal serine of proteins to form the derivative N-methylserine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902661", "l": "positive regulation of glucose mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of glucose mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035017", "l": "cuticle pattern formation", "d": ["The regionalization process that gives rise to the patterns of cell differentiation in the cuticle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0042548", "l": "regulation of photosynthesis, light reaction", "d": ["Any process that modulates the frequency, rate or extent of the light-dependent reaction of photosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901051", "l": "atropine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of atropine. Atropine is the racemic mixture of hyoscyamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0009078", "l": "pyruvate family amino acid metabolic process", "d": ["The chemical reactions and pathways involving any amino acid that requires pyruvate for its synthesis, e.g. alanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042459", "l": "octopine catabolic process to proline", "d": ["The chemical reactions and pathways resulting in the breakdown of octopine into other compounds, including proline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.879406879579491", "identifiers": [{"i": "GO:0002200", "l": "somatic diversification of immune receptors", "d": ["The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0034776", "l": "response to histamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071823", "l": "protein-carbohydrate complex subunit organization", "d": ["Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-carbohydrate complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904761", "l": "negative regulation of myofibroblast differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010722", "l": "regulation of ferrochelatase activity", "d": ["Any process that modulates the frequency, rate or extent of ferrochelatase activity; catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903883", "l": "positive regulation of interleukin-17-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-17-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006675", "l": "mannosyl-inositol phosphorylceramide metabolic process", "d": ["The chemical reactions and pathways involving mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035677", "l": "posterior lateral line neuromast hair cell development", "d": ["The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097310", "l": "cap2 mRNA methylation", "d": ["Methylation of the ribose of the first and second nucleotides of a 5'-capped mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901845", "l": "negative regulation of cell communication by electrical coupling involved in cardiac conduction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0001755", "l": "neural crest cell migration", "d": ["The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110061", "l": "regulation of angiotensin-activated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the angiotensin-activated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019859", "l": "thymine metabolic process", "d": ["The chemical reactions and pathways involving thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019602", "l": "toluene oxidation via 3-hydroxytoluene", "d": ["The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 3-hydroxytoluene (m-cresol)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010745", "l": "negative regulation of macrophage derived foam cell differentiation", "d": ["Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:1905634", "l": "regulation of protein localization to chromatin", "d": ["Any process that modulates the frequency, rate or extent of protein localization to chromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0006612", "l": "protein targeting to membrane", "d": ["The process of directing proteins towards a membrane, usually using signals contained within the protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031203", "l": "post-translational protein targeting to membrane, docking", "d": ["The process in which the signal sequence of a translated protein binds to and forms a complex with the Sec complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045623", "l": "negative regulation of T-helper cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0043954", "l": "cellular component maintenance", "d": ["The organization process that preserves a cellular component in a stable functional or structural state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051655", "l": "maintenance of vesicle location", "d": ["Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904409", "l": "regulation of secretory granule organization", "d": ["Any process that modulates the frequency, rate or extent of secretory granule organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.260243218047506", "identifiers": [{"i": "GO:0048864", "l": "stem cell development", "d": ["The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.848705316821231", "identifiers": [{"i": "GO:0015711", "l": "organic anion transport", "d": ["The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000474", "l": "maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)", "d": ["Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061009", "l": "common bile duct development", "d": ["The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gallbladder. The common bile duct transports bile from the liver and gallbladder to the intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009170", "l": "purine deoxyribonucleoside monophosphate metabolic process", "d": ["The chemical reactions and pathways involving purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044566", "l": "chondrocyte activation", "d": ["A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.781964347917338", "identifiers": [{"i": "GO:0045089", "l": "positive regulation of innate immune response", "d": ["Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097334", "l": "response to perphenazine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a perphenazine stimulus. Perphenazine is a phenothiazine derivative having a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0010595", "l": "positive regulation of endothelial cell migration", "d": ["Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042953", "l": "lipoprotein transport", "d": ["The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900477", "l": "negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of G1/S transition of mitotic cell cycle by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.825956045430587", "identifiers": [{"i": "GO:0045930", "l": "negative regulation of mitotic cell cycle", "d": ["Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.116918913335823", "identifiers": [{"i": "GO:0086001", "l": "cardiac muscle cell action potential", "d": ["An action potential that occurs in a cardiac muscle cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044867", "l": "modulation by host of viral catalytic activity", "d": ["The process in which a host organism effects a change in the enzyme activity of a virus with which it is infected."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0009074", "l": "aromatic amino acid family catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:2000966", "l": "regulation of cell wall polysaccharide catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cell wall polysaccharide catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030237", "l": "female sex determination", "d": ["The specification of female sex of an individual organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900955", "l": "positive regulation of 18-methylnonadec-1-ene metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.155424086811493", "identifiers": [{"i": "GO:0051345", "l": "positive regulation of hydrolase activity", "d": ["Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904976", "l": "cellular response to bleomycin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032615", "l": "interleukin-12 production", "d": ["The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902434", "l": "sulfate import across plasma membrane", "d": ["The directed movement of sulfate from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048080", "l": "negative regulation of cuticle pigmentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048698", "l": "negative regulation of collateral sprouting in absence of injury", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting in the absence of injury."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0006595", "l": "polyamine metabolic process", "d": ["The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035736", "l": "cell proliferation involved in compound eye morphogenesis", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051644", "l": "plastid localization", "d": ["Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901520", "l": "aspyridone B catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aspyridone B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021991", "l": "neural plate thickening", "d": ["The process of apical-basal elongation of individual ectodermal cells during the formation of the neural placode."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042247", "l": "establishment of planar polarity of follicular epithelium", "d": ["Coordinated organization of groups of cells in the plane of a follicular epithelium, such that they all orient to similar coordinates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072274", "l": "metanephric glomerular basement membrane development", "d": ["The process whose specific outcome is the progression of the metanephric glomerular basement membrane over time, from its formation to the mature structure. The metanephric glomerular basement membrane is the basal laminal portion of the metanephric glomerulus which performs the actual filtration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140980", "l": "intracellular nucleoside homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of nucleosides within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030240", "l": "skeletal muscle thin filament assembly", "d": ["The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0002208", "l": "somatic diversification of immunoglobulins involved in immune response", "d": ["The somatic process that results in the generation of sequence diversity of immunoglobulins after induction, and contributes to an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903198", "l": "regulation of L-dopa decarboxylase activity", "d": ["Any process that modulates the frequency, rate or extent of L-dopa decarboxylase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0042138", "l": "meiotic DNA double-strand break formation", "d": ["The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072031", "l": "proximal convoluted tubule segment 1 development", "d": ["The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001844", "l": "protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "d": ["The process in which a protein is incorporated into a mitochondrial membrane as the initial phase of the mitochondrial membrane permeabilization that takes place in the apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080093", "l": "regulation of photorespiration", "d": ["Any process that modulates the rate, frequency or extent of photorespiration. Photorespiration is a light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0140267", "l": "viral entry via permeabilization of host membrane", "d": ["The entry of a virus into the cytoplasm of a host cell, triggered by an interaction between the bilayer of a host membrane and a membrane-penetration capsid protein. Results in release of the virus contents into the host cell cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019122", "l": "peptidyl-D-alanine racemization", "d": ["The formation of peptidyl-D-alanine, by either racemization or from peptidyl-L-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905668", "l": "positive regulation of protein localization to endosome", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to endosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030302", "l": "deoxynucleotide transport", "d": ["The directed movement of a deoxynucleotide, a deoxyribonucleoside in ester linkage to phosphate, commonly at the 5' position of deoxyribose, into, out of or within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048758", "l": "companion cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a companion cell. The companion cell is the specialized parenchyma cell associated with a sieve-tube member in angiosperm phloem and arising from the same mother cell as the sieve-tube member."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.042011961637741", "identifiers": [{"i": "GO:0018130", "l": "heterocycle biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:1902914", "l": "regulation of protein polyubiquitination", "d": ["Any process that modulates the frequency, rate or extent of protein polyubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0014847", "l": "proximal stomach smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the proximal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The proximal stomach, composed of the fundus and upper body, shows low frequency, sustained tonic contractions that are responsible for generating a basal pressure within the stomach."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000710", "l": "meiotic mismatch repair", "d": ["A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules. Correction of the mismatch can result in non-Mendelian segregation of alleles following meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030652", "l": "peptide antibiotic catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of peptides with antibiotic activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905074", "l": "negative regulation of tight junction disassembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tight junction disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035288", "l": "anterior head segmentation", "d": ["Partitioning the insect head anlage into procephalic (labral, (ocular), antennal and intercalary) segments. The procephalic segments lie anterior to the gnathal (posterior head) segments, and are pattered by different segmentation gene cascades to the abdominal, thoracic and posterior head (gnathal) segments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021652", "l": "rhombomere 1 formation", "d": ["The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900828", "l": "D-tyrosine metabolic process", "d": ["The chemical reactions and pathways involving D-tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019061", "l": "uncoating of virus", "d": ["The process by which an incoming virus is disassembled in the host cell to release a replication-competent viral genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048398", "l": "intermediate mesodermal cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an intermediate mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0030041", "l": "actin filament polymerization", "d": ["Assembly of actin filaments by the addition of actin monomers to a filament."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0045620", "l": "negative regulation of lymphocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0002066", "l": "columnar/cuboidal epithelial cell development", "d": ["The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043971", "l": "histone H3-K18 acetylation", "d": ["The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 18 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045460", "l": "sterigmatocystin metabolic process", "d": ["The chemical reactions and pathways involving sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0019520", "l": "aldonic acid metabolic process", "d": ["The chemical reactions and pathways involving aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140057", "l": "vacuole-mitochondria membrane tethering", "d": ["The attachment of a mitochondrial membrane to a vacuolar membrane via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097396", "l": "response to interleukin-17", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039690", "l": "positive stranded viral RNA replication", "d": ["A viral genome replication process where the template genome is positive stranded, single stranded RNA ((+)ssRNA). Replication of the positive strand leads to dsRNA formation, which in turn is transcribed into positive single stranded RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045314", "l": "regulation of compound eye photoreceptor development", "d": ["Any process that modulates the frequency, rate or extent of compound eye photoreceptor development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097744", "l": "renal urate salt excretion", "d": ["The elimination of urate salt or uric acid from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030417", "l": "nicotianamine metabolic process", "d": ["The chemical reactions and pathways involving nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0044468", "l": "envenomation resulting in modulation of blood coagulation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the frequency, rate or extent of blood coagulation in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902849", "l": "positive regulation of neuronal signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of neuronal signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007394", "l": "dorsal closure, elongation of leading edge cells", "d": ["The change in shape of cells at the dorsal-most (leading) edge of the epidermis from being polygonal to being elongated in the dorsal/ventral axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009198", "l": "pyrimidine deoxyribonucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031001", "l": "response to brefeldin A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042202", "l": "N-cyclopropylmelamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N-cyclopropylmelamine, a triazine compound commonly used as an insecticide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006529", "l": "asparagine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of asparagine, 2-amino-3-carbamoylpropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900222", "l": "negative regulation of amyloid-beta clearance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta clearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035314", "l": "scab formation", "d": ["Formation of hardened covering (a scab) at a wound site. The scab has multiple functions including limiting blood loss, providing structural stability to the wound and guarding against infection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061054", "l": "dermatome development", "d": ["The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002910", "l": "positive regulation of peripheral B cell deletion", "d": ["Any process that activates or increases the frequency, rate, or extent of peripheral B cell deletion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019383", "l": "(+)-camphor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (+)-camphor, a bicyclic monoterpene ketone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016562", "l": "protein import into peroxisome matrix, receptor recycling", "d": ["The process in which peroxisome targeting sequence receptors dissociates from cargo proteins and are returned to the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021693", "l": "cerebellar Purkinje cell layer structural organization", "d": ["The process that contributes to the act of creating the structural organization of the cerebellar Purkinje cell layer. This process pertains to the physical shaping of a rudimentary structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0043465", "l": "regulation of fermentation", "d": ["Any process that modulates the frequency, rate or extent of fermentation, the anaerobic enzymatic conversion of organic compounds, especially carbohydrates, to other compounds, especially to ethyl alcohol, resulting in energy in the form of adenosine triphosphate (ATP)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035503", "l": "ureter part of ureteric bud development", "d": ["The development of the portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032340", "l": "positive regulation of inhibin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of inhibin from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036111", "l": "very long-chain fatty-acyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046802", "l": "exit of virus from host cell nucleus by nuclear egress", "d": ["The directed movement of an assembled viral particle out of the host cell nucleus by budding and fusion through the nuclear membranes. In this process, enveloped viral particles are formed by budding through the inner nuclear membrane. These perinuclear enveloped particles then fuse with the outer nuclear membrane to deliver a naked capsid into the host cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032401", "l": "establishment of melanosome localization", "d": ["The directed movement of a melanosome to a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033491", "l": "coniferin metabolic process", "d": ["The chemical reactions and pathways involving coniferin, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenyl beta-D-glucopyranoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903406", "l": "regulation of P-type sodium:potassium-exchanging transporter activity", "d": ["Any process that modulates the frequency, rate or extent of sodium:potassium-exchanging ATPase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090282", "l": "positive regulation of transcription involved in G2/M transition of mitotic cell cycle", "d": ["Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120030", "l": "positive regulation of cilium beat frequency involved in ciliary motility", "d": ["Any process that activates or increases the frequency of cilium beating involved in ciliary motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060097", "l": "cytoskeletal rearrangement involved in phagocytosis, engulfment", "d": ["The assembly, arrangement, or disassembly of cytoskeletal structures that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0046831", "l": "regulation of RNA export from nucleus", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071251", "l": "cellular response to silicon dioxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071952", "l": "conversion of O-phosphoseryl-tRNA to cysteinyl-tRNA", "d": ["The modification process that results in the conversion of O-phosphoserine charged on a tRNA(Cys) to cysteinyl-tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0030437", "l": "ascospore formation", "d": ["The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098828", "l": "modulation of inhibitory postsynaptic potential", "d": ["Any process that modulates the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009846", "l": "pollen germination", "d": ["The physiological and developmental changes that occur in a heterosporous plant pollen grain, beginning with hydration and terminating with the emergence of the pollen tube through the aperture."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070608", "l": "regulation of cell wall (1->3)-alpha-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048166", "l": "mature follicle stage", "d": ["The stage in oogenesis when the antrum is swollen with follicular fluid. The ovum is ready to erupt from the ovary and is arrested at metaphase of the second meiotic division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046514", "l": "ceramide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphingoid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071263", "l": "negative regulation of translational initiation in response to starvation", "d": ["Any process that stops, prevents or reduces the rate of translation initiation, as a result of deprivation of nourishment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905681", "l": "negative regulation of innate immunity memory response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of innate immunity memory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902734", "l": "regulation of receptor-mediated virion attachment to host cell", "d": ["Any process that modulates the frequency, rate or extent of receptor-mediated virion attachment to host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021558", "l": "trochlear nerve development", "d": ["The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0002462", "l": "tolerance induction to nonself antigen", "d": ["Tolerance induction in response to nonself antigens."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035260", "l": "internal genitalia morphogenesis", "d": ["The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901816", "l": "beta-zeacarotene metabolic process", "d": ["The chemical reactions and pathways involving beta-zeacarotene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060738", "l": "epithelial-mesenchymal signaling involved in prostate gland development", "d": ["Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted and contributes to the progression of the prostate gland over time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015811", "l": "L-cystine transport", "d": ["The directed movement of L-cystine (also known as dicysteine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0086066", "l": "atrial cardiac muscle cell to AV node cell communication", "d": ["The process that mediates interactions between an atrial cardiomyocyte and its surroundings that contributes to the process of the atrial cardiomyocyte communicating with an AV node cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903996", "l": "negative regulation of non-membrane spanning protein tyrosine kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.327400668044291", "identifiers": [{"i": "GO:0045936", "l": "negative regulation of phosphate metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0110021", "l": "cardiac muscle myoblast proliferation", "d": ["The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048902", "l": "anterior lateral line neuromast deposition", "d": ["The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing anterior lateral line."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043651", "l": "linoleic acid metabolic process", "d": ["The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010511", "l": "regulation of phosphatidylinositol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006465", "l": "signal peptide processing", "d": ["The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "32.443339889076675", "identifiers": [{"i": "GO:0048598", "l": "embryonic morphogenesis", "d": ["The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905920", "l": "positive regulation of CoA-transferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of CoA-transferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0002407", "l": "dendritic cell chemotaxis", "d": ["The movement of a dendritic cell in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0021744", "l": "dorsal motor nucleus of vagus nerve development", "d": ["The process whose specific outcome is the progression of the dorsal motor nucleus of the vagus nerve over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140018", "l": "regulation of cytoplasmic translational fidelity", "d": ["Any process that modulates the ability of the cytoplasmic translational apparatus to interpret the genetic code."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0042844", "l": "glycol metabolic process", "d": ["The chemical reactions and pathways involving glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021786", "l": "branchiomotor neuron axon guidance in neural tube", "d": ["The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098974", "l": "postsynaptic actin cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002069", "l": "columnar/cuboidal epithelial cell maturation", "d": ["The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046278", "l": "3,4-dihydroxybenzoate metabolic process", "d": ["The chemical reactions and pathways involving protocatechuate, the anion of protocatechuic acid (3,4-dihydroxybenzoic acid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033131", "l": "regulation of glucokinase activity", "d": ["Any process that modulates the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075269", "l": "positive regulation of aecium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071330", "l": "cellular response to trehalose-6-phosphate stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903166", "l": "cellular response to polycyclic arene", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010493", "l": "Lewis a epitope biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-(1->4)[Gal-beta-(1->3)]GlcNAc) characteristic of plant protein N-linked oligosaccharides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0032275", "l": "luteinizing hormone secretion", "d": ["The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007426", "l": "tracheal outgrowth, open tracheal system", "d": ["The projection of branches of an open tracheal system towards their target tissues. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006856", "l": "eye pigment precursor transport", "d": ["The directed movement of eye pigment precursors, the inactive forms of visual pigments, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902229", "l": "regulation of intrinsic apoptotic signaling pathway in response to DNA damage", "d": ["Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903375", "l": "facioacoustic ganglion development", "d": ["The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0071888", "l": "macrophage apoptotic process", "d": ["Any apoptotic process in a macrophage, a mononuclear phagocyte present in a variety of tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043554", "l": "aerobic respiration, using arsenite as electron donor", "d": ["The oxidation of arsenite to arsenate, using oxygen (O2) as the electron acceptor. Arsenite oxidase provides electrons to an electron carrier which transfers them to oxygen utilizing respiratory systems."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042794", "l": "plastid rRNA transcription", "d": ["The synthesis of ribosomal RNA (rRNA) from a plastid DNA template, usually by a specific plastid RNA polymerase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905232", "l": "cellular response to L-glutamate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035122", "l": "embryonic medial fin morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035683", "l": "memory T cell extravasation", "d": ["The migration of a memory T cell from the blood vessels into the surrounding tissue. A memory T cell is a distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009171", "l": "purine deoxyribonucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060998", "l": "regulation of dendritic spine development", "d": ["Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0009113", "l": "purine nucleobase biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003371", "l": "establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration", "d": ["Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009413", "l": "response to flooding", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating flooding, short-term immersion in water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0110154", "l": "RNA decapping", "d": ["Cleavage of the 5'-cap of an RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106380", "l": "purine ribonucleotide salvage", "d": ["Any process which produces a purine ribonucleotide from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903800", "l": "positive regulation of miRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of microRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900560", "l": "austinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of austinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071105", "l": "response to interleukin-11", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048342", "l": "paraxial mesodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a paraxial mesoderm cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106035", "l": "protein maturation by [4Fe-4S] cluster transfer", "d": ["The transfer of an assembled 4Fe-4S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042638", "l": "exogen", "d": ["The shedding phase of the hair cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0051447", "l": "negative regulation of meiotic cell cycle", "d": ["Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051898", "l": "negative regulation of protein kinase B signaling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0051339", "l": "regulation of lyase activity", "d": ["Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010166", "l": "wax metabolic process", "d": ["The chemical reactions and pathways involving wax, a compound containing C16 and C18 fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0051157", "l": "arabitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0031049", "l": "programmed DNA elimination", "d": ["A process in which genomic fragments or entire chromosomes are eliminated from somatic cells or from micronuclei of ciliates. This process occurs in the developing macronucleus (anlage) of a ciliate, as well as in other species, including vertebrates and is an irreversible mechanism of gene silencing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035687", "l": "T-helper 1 cell extravasation", "d": ["The migration of a T-helper 1 cell from the blood vessels into the surrounding tissue. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061624", "l": "fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0048898", "l": "anterior lateral line system development", "d": ["The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0006705", "l": "mineralocorticoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060006", "l": "angular vestibuloocular reflex", "d": ["A vestibular reflex by which a response to an angular acceleration stimulus begins with an afferent nerve impulse from a receptor in the semi-circular canal and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090110", "l": "COPII-coated vesicle cargo loading", "d": ["The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008258", "l": "head involution", "d": ["Movement of the anterior ectoderm to the interior of the embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "36.702053925545314", "identifiers": [{"i": "GO:0060429", "l": "epithelium development", "d": ["The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061743", "l": "motor learning", "d": ["Any process in which an organism acquires a novel neuromuscular action or movement as the result of experience."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042369", "l": "vitamin D catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046109", "l": "uridine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901878", "l": "positive regulation of calcium ion binding", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009562", "l": "embryo sac nuclear migration", "d": ["The directed movement of an embryo sac nucleus to the pole or center of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902708", "l": "response to plumbagin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033007", "l": "negative regulation of mast cell activation involved in immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034420", "l": "co-translational protein acetylation", "d": ["The addition of an acetyl group to one or more amino acids in a protein, occurring before the protein has been completely translated and released from the ribosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046367", "l": "allose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050838", "l": "peptidyl-5-hydroxy-L-lysine trimethylation", "d": ["The methylation of 5-hydroxy-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000359", "l": "regulation of binding of sperm to zona pellucida", "d": ["Any process that modulates the frequency, rate or extent of binding of sperm to the zona pellucida."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:0000096", "l": "sulfur amino acid metabolic process", "d": ["The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0000393", "l": "spliceosomal conformational changes to generate catalytic conformation", "d": ["Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0022406", "l": "membrane docking", "d": ["The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.06379513530257", "identifiers": [{"i": "GO:0071241", "l": "cellular response to inorganic substance", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002042", "l": "cell migration involved in sprouting angiogenesis", "d": ["The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018950", "l": "o-xylene metabolic process", "d": ["The chemical reactions and pathways involving o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0110112", "l": "regulation of lipid transporter activity", "d": ["Any process that modulates the frequency, rate, or extent of lipid transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061577", "l": "calcium ion transmembrane transport via high voltage-gated calcium channel", "d": ["A process in which a calcium ion is transported from one side of a membrane to the other by means of a high voltage-gated calcium channel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048601", "l": "oocyte morphogenesis", "d": ["The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032972", "l": "regulation of muscle filament sliding speed", "d": ["Any process that modulates the velocity of muscle filament sliding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.598265520774746", "identifiers": [{"i": "GO:0009725", "l": "response to hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061669", "l": "spontaneous neurotransmitter secretion", "d": ["Neurotransmitter secretion that occurs in the absence of the action of a secretagogue or a presynaptic action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902730", "l": "positive regulation of proteoglycan biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002426", "l": "immunoglobulin production in mucosal tissue", "d": ["The synthesis and release of immunoglobulin in the mucosal tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902529", "l": "negative regulation of protein linear polyubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein linear polyubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061210", "l": "cell-cell signaling involved in mesonephros development", "d": ["Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000248", "l": "negative regulation of establishment or maintenance of neuroblast polarity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032379", "l": "positive regulation of intracellular lipid transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900890", "l": "regulation of pentadecane metabolic process", "d": ["Any process that modulates the frequency, rate or extent of pentadecane metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.824513090543306", "identifiers": [{"i": "GO:0044786", "l": "cell cycle DNA replication", "d": ["The DNA-dependent DNA replication that takes place as part of the cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0051589", "l": "negative regulation of neurotransmitter transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060467", "l": "negative regulation of fertilization", "d": ["Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904728", "l": "positive regulation of replicative senescence", "d": ["Any process that activates or increases the frequency, rate or extent of replicative senescence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034346", "l": "positive regulation of type III interferon production", "d": ["Any process that activates or increases the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2000757", "l": "negative regulation of peptidyl-lysine acetylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-lysine acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075254", "l": "negative regulation of uredospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043477", "l": "pigment biosynthetic process involved in pigment accumulation", "d": ["The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, resulting in pigment accumulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.442476542024195", "identifiers": [{"i": "GO:0006357", "l": "regulation of transcription by RNA polymerase II", "d": ["Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009762", "l": "NADP-malic enzyme C4 photosynthesis", "d": ["The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NADP-malic enzyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "32.017978914258251", "identifiers": [{"i": "GO:0040016", "l": "embryonic cleavage", "d": ["The first few specialized divisions of an activated animal egg."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0080120", "l": "CAAX-box protein maturation", "d": ["A series of specific posttranslational modifications to the CAAX box region of CAAX box proteins. CAAX box proteins are eukaryotic proteins that contain a CAAX motif where the C is a cysteine, the two A residues are aliphatic amino acids and the X can be one of several amino acids. The CAAX-box proteins undergo three sequential, enzymatic, post-translational modifications essential to their targeting: First, the proteins are prenylated by one of two prenyltransferases called farnesyltransferase and geranylgeranyltransferase-I. Prenylation results in the covalent attachment of either farnesyl or geranylgeranyl isoprenoid groups to the cysteine in the CAAX box motif. Prenylation is followed by proteolytic removal of the last three amino acids of the protein (AAX). Finally, the newly exposed carboxylate group of the isoprenylcysteine is methylated by an ER-associated prenyl-dependent carboxylmethyltransferase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010083", "l": "regulation of vegetative meristem growth", "d": ["Any process involved in maintaining the size and shape of a vegetative meristem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090371", "l": "regulation of glycerol transport", "d": ["Any process that modulates the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901791", "l": "3-(2,3-dihydroxyphenyl)propanoate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-(2,3-dihydroxyphenyl)propanoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052344", "l": "positive regulation by symbiont of host phytoalexin production", "d": ["Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044250", "l": "negative regulation of metabolic activity involved in hibernation", "d": ["The slowing of metabolic processes to very low levels in order to conserve energy as a part of hibernation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0034305", "l": "regulation of asexual sporulation", "d": ["Any process that modulates the frequency, rate or extent of spore formation from the products of mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045706", "l": "positive regulation of salivary gland boundary specification", "d": ["Any process that activates or increases the frequency, rate or extent of salivary gland determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033310", "l": "chlorophyll a catabolic process", "d": ["The chemical reactions and pathways leading to the breakdown of chlorophyll a."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035973", "l": "aggrephagy", "d": ["Selective degradation of protein aggregates by macroautophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009646", "l": "response to absence of light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902724", "l": "positive regulation of skeletal muscle satellite cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of skeletal muscle satellite cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903538", "l": "regulation of meiotic cell cycle process involved in oocyte maturation", "d": ["Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061248", "l": "mesonephric glomerulus vasculature morphogenesis", "d": ["The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000283", "l": "negative regulation of amino acid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061529", "l": "epinephrine secretion, neurotransmission", "d": ["The regulated release of epinephrine by a cell in which the epinephrine acts as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036269", "l": "swimming behavior", "d": ["The response to external or internal stimuli that results in the locomotory process of swimming. Swimming is the self-propelled movement of an organism through the water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0045823", "l": "positive regulation of heart contraction", "d": ["Any process that activates or increases the frequency, rate or extent of heart contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901494", "l": "regulation of cysteine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cysteine metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0019359", "l": "nicotinamide nucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinamide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010757", "l": "negative regulation of plasminogen activation", "d": ["Any process that decreases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0043449", "l": "cellular alkene metabolic process", "d": ["The chemical reactions and pathways involving an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n, as carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0048636", "l": "positive regulation of muscle organ development", "d": ["Any process that activates, maintains or increases the rate of muscle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0050964", "l": "detection of electrical stimulus involved in electroception", "d": ["The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072266", "l": "metanephric capsule formation", "d": ["The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000658", "l": "positive regulation of apolipoprotein binding", "d": ["Any process that activates or increases the frequency, rate or extent of apolipoprotein binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019554", "l": "glutamate catabolic process to oxaloacetate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including oxaloacetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0046688", "l": "response to copper ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002779", "l": "antibacterial peptide secretion", "d": ["The regulated release of an antibacterial peptide from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904365", "l": "regulation of chemokinesis", "d": ["Any process that modulates the frequency, rate or extent of chemokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0080155", "l": "regulation of double fertilization forming a zygote and endosperm", "d": ["Any process that modulates the rate, frequency or extent of double fertilization forming a zygote and endosperm. Double fertilization forming a zygote and endosperm is a type of fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090112", "l": "COPII vesicle uncoating", "d": ["The process in which COPII vesicle coat proteins are disassembled, and released."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003398", "l": "glial cell differentiation involved in amphid sensory organ development", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the amphid sensory organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003131", "l": "mesodermal-endodermal cell signaling", "d": ["Any process that mediates the transfer of information from mesodermal cells to endodermal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0005989", "l": "lactose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lactose, the disaccharide galactopyranosyl-glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001293", "l": "malonyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving malonyl-CoA, the S-malonyl derivative of coenzyme A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0035924", "l": "cellular response to vascular endothelial growth factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vascular endothelial growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045970", "l": "negative regulation of juvenile hormone catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0097107", "l": "postsynaptic density assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110141", "l": "L-glutamate import into mitochondrion", "d": ["The process in which L-glutamate is transported from the cytosol into the mitochondrial matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032595", "l": "B cell receptor transport within lipid bilayer", "d": ["The directed movement of a B cell receptor within a lipid bilayer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014040", "l": "positive regulation of Schwann cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072514", "l": "trehalose transport in response to water deprivation", "d": ["The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of deprivation of water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904543", "l": "negative regulation of free ubiquitin chain polymerization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of free ubiquitin chain polymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0075286", "l": "regulation of sporangiospore formation", "d": ["Any process that modulates the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090205", "l": "positive regulation of cholesterol metabolic process", "d": ["Any process that increases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140650", "l": "radial glia-guided pyramidal neuron migration", "d": ["The radial migration of a pyramidal neuron along radial glial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051364", "l": "N-terminal peptidyl-proline N-formylation", "d": ["The formylation of the N-terminal proline of proteins to form the derivative N-formylproline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015776", "l": "capsular polysaccharide transport", "d": ["The directed movement of capsular polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0044788", "l": "modulation by host of viral process", "d": ["A process in which a host organism modulates the frequency, rate or extent of any of a process being mediated by a virus with which it is infected."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001239", "l": "regulation of extrinsic apoptotic signaling pathway in absence of ligand", "d": ["Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097041", "l": "phenolic phthiocerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phenolic phthiocerol, a phthiocerol derivative having a 4-hydroxyphenyl substituent at the 29-position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904429", "l": "regulation of t-circle formation", "d": ["Any process that modulates the frequency, rate or extent of t-circle formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905744", "l": "regulation of mRNA cis splicing, via spliceosome", "d": ["Any process that modulates the frequency, rate or extent of mRNA cis splicing, via spliceosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044861", "l": "protein transport into plasma membrane raft", "d": ["The directed movement of a protein into a plasma membrane raft."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000428", "l": "regulation of neutrophil aggregation", "d": ["Any process that modulates the frequency, rate or extent of neutrophil aggregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045661", "l": "regulation of myoblast differentiation", "d": ["Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060875", "l": "lateral semicircular canal development", "d": ["The progession of the lateral semicircular canal from its initial formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042432", "l": "indole biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905351", "l": "pericyte cell migration", "d": ["The orderly movement of a pericyte cell from one site to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000048", "l": "negative regulation of cell-cell adhesion mediated by cadherin", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell-cell adhesion mediated by cadherin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.07563785880906", "identifiers": [{"i": "GO:0042303", "l": "molting cycle", "d": ["The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904073", "l": "regulation of trophectodermal cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002591", "l": "positive regulation of antigen processing and presentation of peptide antigen via MHC class I", "d": ["Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061808", "l": "negative regulation of DNA recombination at centromere", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination at the centromere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:1903436", "l": "regulation of mitotic cytokinetic process", "d": ["Any process that modulates the frequency, rate or extent of mitotic cytokinetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042850", "l": "L-sorbose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010957", "l": "negative regulation of vitamin D biosynthetic process", "d": ["Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905603", "l": "regulation of blood-brain barrier permeability", "d": ["Any process that modulates blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050428", "l": "3'-phosphoadenosine 5'-phosphosulfate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046005", "l": "positive regulation of circadian sleep/wake cycle, REM sleep", "d": ["Any process that activates or increases the duration or quality of rapid eye movement (REM) sleep."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033859", "l": "furaldehyde metabolic process", "d": ["The chemical reactions and pathways involving furaldehyde, a furan ring-containing aldehyde compound which can be formed from the thermal decomposition of biomass."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904569", "l": "regulation of selenocysteine incorporation", "d": ["Any process that modulates the frequency, rate or extent of selenocysteine incorporation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051479", "l": "mannosylglycerate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046181", "l": "ketogluconate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006251", "l": "dCDP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dCDP, deoxycytidine 5'-diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.675373588411375", "identifiers": [{"i": "GO:0001701", "l": "in utero embryonic development", "d": ["The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036276", "l": "response to antidepressant", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.98780181426379", "identifiers": [{"i": "GO:0089718", "l": "amino acid import across plasma membrane", "d": ["The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097231", "l": "cell motility in response to calcium ion", "d": ["Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a calcium ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002899", "l": "negative regulation of central B cell deletion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell deletion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007174", "l": "epidermal growth factor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of epidermal growth factor (EGF), following internalization of the receptor-bound ligand into the signal-receiving cell. Full breakdown of epidermal growth factor results in a ligand that is unable to bind and activate its receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106041", "l": "positive regulation of GABA-A receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of GABA-A receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010599", "l": "lsiRNA processing", "d": ["A process leading to the generation of a functional long small interfering RNA (lsiRNA). lsiRNAs are class of siRNAs 30 to 40 nt in length. lsiRNAs are induced by pathogen infection or under specific growth conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000168", "l": "negative regulation of planar cell polarity pathway involved in neural tube closure", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902998", "l": "positive regulation of neurofibrillary tangle assembly", "d": ["Any process that activates or increases the frequency, rate or extent of neurofibrillary tangle assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006849", "l": "plasma membrane pyruvate transport", "d": ["The directed movement of pyruvate, 2-oxopropanoate, across a plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1990949", "l": "metaphase/anaphase transition of meiosis I", "d": ["The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061883", "l": "clathrin-dependent endocytosis involved in vitellogenesis", "d": ["A clathrin-mediated endocytosis process whereby yolk proteins are internalized and trafficked through the endocytic pathway for yolk deposition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0110127", "l": "phloem unloading", "d": ["The process of unloading solutes that are produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045951", "l": "positive regulation of mitotic recombination", "d": ["Any process that activates or increases the frequency, rate or extent of DNA recombination during mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904970", "l": "brush border assembly", "d": ["The aggregation, arrangement and bonding together of adjacent microvilli through the formation of Ca(2+)-dependent adhesion links between them, forming a brush border."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001928", "l": "regulation of exocyst assembly", "d": ["Any process that modulates the frequency, rate or extent of exocyst assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060084", "l": "synaptic transmission involved in micturition", "d": ["The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902632", "l": "positive regulation of membrane hyperpolarization", "d": ["Any process that activates or increases the frequency, rate or extent of membrane hyperpolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905237", "l": "response to cyclosporin A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905858", "l": "regulation of heparan sulfate proteoglycan binding", "d": ["Any process that modulates the frequency, rate or extent of heparan sulfate proteoglycan binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070400", "l": "teichoic acid D-alanylation", "d": ["The formation of a D-alanyl ester of teichoic acid. Alanylation of teichoic acids modulates the properties of the bacterial cell wall and modulates the inflammatory properties of the teichoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000990", "l": "positive regulation of hemicellulose catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of hemicellulose catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.161881760686384", "identifiers": [{"i": "GO:0048925", "l": "lateral line system development", "d": ["The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061059", "l": "positive regulation of peptidoglycan recognition protein signaling pathway", "d": ["Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046051", "l": "UTP metabolic process", "d": ["The chemical reactions and pathways involving UTP, uridine (5'-)triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072584", "l": "caveolin-mediated endocytosis", "d": ["An endocytosis process that begins when material is taken up into plasma membrane caveolae, which then pinch off to form endocytic caveolar carriers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018921", "l": "3-hydroxybenzyl alcohol metabolic process", "d": ["The chemical reactions and pathways involving 3-hydroxybenzyl alcohol, an aromatic compound which is an intermediate in several metabolic pathways, including the biosynthesis of patulin, a toxin and antiviral agent produced by some moulds such as Penicillium patulinum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1900369", "l": "negative regulation of post-transcriptional gene silencing by regulatory ncRNA", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of post-transcriptional gene silencing by RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.003741351937961", "identifiers": [{"i": "GO:0051346", "l": "negative regulation of hydrolase activity", "d": ["Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0001583", "l": "detection of chemical stimulus involved in sensory perception of salty taste", "d": ["The series of events required for a salty taste stimulus to be received and converted to a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060644", "l": "mammary gland epithelial cell differentiation", "d": ["The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106393", "l": "regulation of palmitic acid catabolic process", "d": ["Any process that modulates the frequency, rate or extent of a palmitic acid catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061281", "l": "specification of mesonephric connecting tubule identity", "d": ["The process in which the connecting tubule of the mesonephric nephron acquires its identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075190", "l": "negative regulation of hyphopodium formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000763", "l": "positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process", "d": ["Any positive regulation of transcription from RNA polymerase II promoter that is involved in norepinephrine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099404", "l": "mitotic sister chromatid cohesion, telomeric", "d": ["The cell cycle process in which telomeres of sister chromatids are joined during mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.824318789188837", "identifiers": [{"i": "GO:0022408", "l": "negative regulation of cell-cell adhesion", "d": ["Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098870", "l": "action potential propagation", "d": ["The propagation of an action potential along the plane of an excitable membrane. Action potentials typically propagate once triggered because the depolarization of adjacent membrane regions due to an action potential crosses the firing threshold."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0032231", "l": "regulation of actin filament bundle assembly", "d": ["Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052784", "l": "reuteran biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010448", "l": "vegetative meristem growth", "d": ["The increase in size or mass of a vegetative meristem, a population of undifferentiated cells in a plant shoot which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into lateral organ primordia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098758", "l": "response to interleukin-8", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032926", "l": "negative regulation of activin receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0045733", "l": "acetate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045657", "l": "positive regulation of monocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of monocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007120", "l": "axial cellular bud site selection", "d": ["The process of defining the next site of bud emergence adjacent to the last site of bud emergence on a budding cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010603", "l": "regulation of cytoplasmic mRNA processing body assembly", "d": ["Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060666", "l": "dichotomous subdivision of terminal units involved in salivary gland branching", "d": ["The process in which a salivary epithelial cord bifurcates at its end."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902690", "l": "positive regulation of NAD metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of NAD metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006106", "l": "fumarate metabolic process", "d": ["The chemical reactions and pathways involving fumarate, the anion of trans-1,2-ethenedicarboxylic acid, the diastereoisomer of maleate. It is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0008215", "l": "spermine metabolic process", "d": ["The chemical reactions and pathways involving spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0042118", "l": "endothelial cell activation", "d": ["The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903355", "l": "negative regulation of distal tip cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of distal tip cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000117", "l": "negative regulation of cysteine-type endopeptidase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cysteine-type endopeptidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090414", "l": "molybdate ion export from vacuole", "d": ["The directed movement of molybdate ions out of the vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075256", "l": "regulation of teliospore formation", "d": ["Any process that modulates the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.706877558974412", "identifiers": [{"i": "GO:0007596", "l": "blood coagulation", "d": ["The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0035290", "l": "trunk segmentation", "d": ["Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0050761", "l": "depsipeptide metabolic process", "d": ["The chemical reactions and pathways involving depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075194", "l": "positive regulation of haustorium mother cell formation", "d": ["Any process that activates or increases the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014710", "l": "negative regulation of somitomeric trunk muscle development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072498", "l": "embryonic skeletal joint development", "d": ["The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeletal joints over time, from formation to mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072180", "l": "mesonephric duct morphogenesis", "d": ["The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048683", "l": "regulation of collateral sprouting of intact axon in response to injury", "d": ["Any process that modulates the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.071082486141265", "identifiers": [{"i": "GO:0006413", "l": "translational initiation", "d": ["The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901968", "l": "regulation of polynucleotide 3'-phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of polynucleotide 3'-phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000239", "l": "negative regulation of tRNA export from nucleus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA export from nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2000622", "l": "regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "d": ["Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072763", "l": "cellular response to hesperadin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:0045123", "l": "cellular extravasation", "d": ["The migration of a leukocyte from the blood vessels into the surrounding tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050948", "l": "positive regulation of early stripe melanocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of early stripe melanocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0043383", "l": "negative T cell selection", "d": ["The process of elimination of immature T cells which react strongly with self-antigens."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900138", "l": "negative regulation of phospholipase A2 activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase A2 activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090116", "l": "C-5 methylation of cytosine", "d": ["The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014839", "l": "myoblast migration involved in skeletal muscle regeneration", "d": ["The process in which a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900315", "l": "regulation of maltopentaose transport", "d": ["Any process that modulates the frequency, rate or extent of maltopentaose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009239", "l": "enterobactin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070143", "l": "mitochondrial alanyl-tRNA aminoacylation", "d": ["The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000744", "l": "positive regulation of anterior head development", "d": ["Any process that activates or increases the frequency, rate or extent of anterior head development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905600", "l": "regulation of receptor-mediated endocytosis involved in cholesterol transport", "d": ["Any process that modulates the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034695", "l": "response to prostaglandin E", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.557025519145952", "identifiers": [{"i": "GO:0010564", "l": "regulation of cell cycle process", "d": ["Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071217", "l": "cellular response to external biotic stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010784", "l": "proboscis morphogenesis, clypeo-labral disc-derived", "d": ["The process in which the anatomical structures of the proboscis that are derived from the clypeo-labral disc are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060962", "l": "regulation of ribosomal protein gene transcription by RNA polymerase II", "d": ["Any process that modulates the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072232", "l": "metanephric proximal convoluted tubule segment 2 development", "d": ["The process whose specific outcome is the progression of the S2 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the metanephric proximal tubule is involved in reabsorption of water and sodium chloride."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051504", "l": "diterpene phytoalexin precursor biosynthetic process pathway", "d": ["A branched pathway that produces the precursors to four structurally distinct types of polycyclic diterpenes. The pathway starts with the cyclization of geranylgeranyl diphosphate into ent-copalyl diphosphate and syn-copalyl diphosphate. The catalytic conversion by diterpene cyclases of these two compounds produces the four diterpene hydrocarbons which are precursors to the four structurally distinct classes of diterpene phytoalexins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099069", "l": "synaptic vesicle tethering involved in synaptic vesicle exocytosis", "d": ["The initial, indirect interaction between a synaptic vesicle membrane and a the preseynaptic membrane active zone. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. This process is distinct from and prior to synaptic vesicle priming and fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032415", "l": "regulation of sodium:proton antiporter activity", "d": ["Any process that modulates the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904433", "l": "negative regulation of ferrous iron binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ferrous iron binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000711", "l": "positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric", "d": ["Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000752", "l": "agglutination involved in conjugation with cellular fusion", "d": ["The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation with cellular fusion of a unicellular organism. An example of this process is agglutination in Saccharomyces cerevisiae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0016126", "l": "sterol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905607", "l": "negative regulation of presynapse assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905287", "l": "positive regulation of G2/M transition of mitotic cell cycle involved in cellular response to nitrogen starvation", "d": ["Any positive regulation of G2/M transition of mitotic cell cycle that is involved in cellular response to nitrogen starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.685364931984026", "identifiers": [{"i": "GO:0051054", "l": "positive regulation of DNA metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160069", "l": "surfactant secretion", "d": ["The regulated release of surfactant by a cell or tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010392", "l": "galactoglucomannan metabolic process", "d": ["The chemical reactions and pathways involving galactoglucomannan, a polysaccharide composed of D-glucose, D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) decorated with a mixture of D-glucose and D-galactose side-units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0051124", "l": "synaptic assembly at neuromuscular junction", "d": ["The assembly of a synapse at a neuromuscular junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034699", "l": "response to luteinizing hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903912", "l": "negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum stress-induced eiF2alpha phosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0052803", "l": "imidazole-containing compound metabolic process", "d": ["The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039587", "l": "suppression by virus of host tetherin activity", "d": ["Any process in which a virus stops, prevents, or reduces the activity of host tetherin activity. Tetherin (also known as BST2) is an alpha interferon-inducible cellular factor that impairs the release of many enveloped viruses. By blocking tetherin activity, many viruses circumvent its antiviral effects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0009807", "l": "lignan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903127", "l": "positive regulation of centriole-centriole cohesion", "d": ["Any process that activates or increases the frequency, rate or extent of centriole-centriole cohesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055108", "l": "Golgi to transport vesicle transport", "d": ["The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140273", "l": "repair of mitotic kinetochore microtubule attachment defect", "d": ["The mitotic cell cycle process where kinetochore microtubule attachment defects are corrected."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904002", "l": "regulation of sebum secreting cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of sebum secreting cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904371", "l": "negative regulation of protein localization to actin cortical patch", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to actin cortical patch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061744", "l": "motor behavior", "d": ["The specific neuromuscular movement of a single organism in response to external or internal stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052067", "l": "antiphagocytosis", "d": ["Any process in which a symbiont avoids phagocytosis by a host cell, for example a phagocyte or a macrophage. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046686", "l": "response to cadmium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0036260", "l": "RNA capping", "d": ["The sequence of enzymatic reactions by which a cap structure is added to the 5' end of nascent RNA polymerase transcripts. Examples of RNA capping include 7-methyl-G caps found on all RNA polymerase II transcripts and nucleotide-containing cofactor caps, such as NAD(H) or FAD, found on bacterial trancripts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901592", "l": "negative regulation of double-strand break repair via break-induced replication", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via break-induced replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021741", "l": "spinal trigeminal nucleus development", "d": ["The process whose specific outcome is the progression of the spinal trigeminal nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021729", "l": "superior reticular formation development", "d": ["The process whose specific outcome is the progression of the superior reticular formation over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0055113", "l": "epiboly involved in gastrulation with mouth forming second", "d": ["The expansion of one cell sheet over other cells involved in deuterostomic gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140652", "l": "pyripyropene A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyripyropene A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097432", "l": "hippocampal pyramidal neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a hippocampal pyramidal neuron, a pyramidal cell of the hippocampus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0051783", "l": "regulation of nuclear division", "d": ["Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000466", "l": "negative regulation of glycogen (starch) synthase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glycogen (starch) synthase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071276", "l": "cellular response to cadmium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070599", "l": "fungal-type cell wall (1->3)-alpha-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150111", "l": "regulation of transepithelial transport", "d": ["Any process that modulates the frequency, rate or extent of transepithelial transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000762", "l": "pheromone-induced unidirectional conjugation", "d": ["Unidirectional transfer of genetic information triggered by to a pheromone signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0098915", "l": "membrane repolarization during ventricular cardiac muscle cell action potential", "d": ["The process in which ions are transported across a membrane such that the ventricular cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003040", "l": "excitation of vasomotor center by aortic body chemoreceptor signaling", "d": ["The process in which the molecular signal from an aortic body is relayed to the vasomotor center, causing it to signal an increase arterial pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044601", "l": "protein denucleotidylation", "d": ["The removal of a nucleotide from a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034159", "l": "regulation of toll-like receptor 8 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 8 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010090", "l": "trichome morphogenesis", "d": ["The process in which the structures of a hair cell (trichome) cell are generated and organized. This process occurs while the initially relatively unspecialized epidermal cell is acquiring the specialized features of a hair cell. An example of this process is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010311", "l": "lateral root formation", "d": ["The process that gives rise to a lateral root. This process pertains to the initial formation of a structure from unspecified parts. A lateral root primordium represents an organized group of cells derived from the root pericycle that will differentiate into a new root, as opposed to the initiation of the main root from the embryo proper."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071242", "l": "cellular response to ammonium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905094", "l": "regulation of apolipoprotein A-I-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060489", "l": "planar dichotomous subdivision of terminal units involved in lung branching morphogenesis", "d": ["The process in which a lung bud bifurcates parallel to the plane of the previous bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045751", "l": "negative regulation of Toll signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the Tl signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901190", "l": "regulation of formation of translation initiation ternary complex", "d": ["Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098756", "l": "response to interleukin-21", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904522", "l": "positive regulation of myofibroblast cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of myofibroblast cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900452", "l": "regulation of long-term synaptic depression", "d": ["Any process that modulates the frequency, rate or extent of long term synaptic depression."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902346", "l": "meiotic strand displacement involved in double-strand break repair via SDSA", "d": ["Any meiotic strand displacement that is involved in double-strand break repair via synthesis-dependent strand annealing (SDSA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000875", "l": "negative regulation of glyoxylate cycle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glyoxylate cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140624", "l": "EGAD pathway", "d": ["The protein catabolic pathway which selectively extracts ER-resident membrane proteins exported to the Golgi and endosomes for degradation by cytosolic proteasomes. It begins with phosphorylation of the ER-resident membrane protein, which triggers export of the protein from the ER to the Golgi and endosomes, followed by polyubiquitination by the Dsc E3 ubiquitin ligase complex and extraction of the ubiquitinated target, and ends with proteasomal degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080005", "l": "photosystem stoichiometry adjustment", "d": ["Adjustment of Photosystem I/Photosystem II ratio in response to light conditions. The function of photosystem stoichiometry adjustment is to compensate for any deficiency in energy conversion at either photosystem I or photosystem II by increasing the quantity the photosystem that will otherwise become the rate-limiting to overall photosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0032092", "l": "positive regulation of protein binding", "d": ["Any process that activates or increases the frequency, rate or extent of protein binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080159", "l": "zygote elongation", "d": ["The process in which the zygote irreversibly increases in size in one dimension after fertilization. An example of such a process is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052085", "l": "suppression by symbiont of host T-cell mediated immune response", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0032466", "l": "negative regulation of cytokinesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0007442", "l": "hindgut morphogenesis", "d": ["The process in which the anatomical structures of the hindgut are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098816", "l": "mini excitatory postsynaptic potential", "d": ["A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0046112", "l": "nucleobase biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060580", "l": "ventral spinal cord interneuron fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron regardless of its environment; upon determination, the cell fate cannot be reversed. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0003351", "l": "epithelial cilium movement involved in extracellular fluid movement", "d": ["The directed, self-propelled movement of cilia of epithelial cells. Depending on the type of cell, there may be one or many cilia per cell. This movement is usually coordinated between many epithelial cells, and serves to move extracellular fluid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.644186068201407", "identifiers": [{"i": "GO:0001508", "l": "action potential", "d": ["A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0042051", "l": "compound eye photoreceptor development", "d": ["The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.207992593949683", "identifiers": [{"i": "GO:0008285", "l": "negative regulation of cell population proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901121", "l": "tobramycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tobramycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035773", "l": "insulin secretion involved in cellular response to glucose stimulus", "d": ["The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071320", "l": "cellular response to cAMP", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010650", "l": "positive regulation of cell communication by electrical coupling", "d": ["Any process that increases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902698", "l": "pentose catabolic process to butyrate", "d": ["The chemical reactions and pathways resulting in the breakdown of pentose to butyrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0086011", "l": "membrane repolarization during action potential", "d": ["The process in which ions are transported across a membrane such that the membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060442", "l": "branching involved in prostate gland morphogenesis", "d": ["The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015897", "l": "organomercurial transport", "d": ["The process in which an organomercurial compound is transported across a membrane. Organomercurial substances are any organic compound containing a mercury atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060953", "l": "cardiac glial cell fate commitment", "d": ["The commitment of cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1902621", "l": "actomyosin contractile ring disassembly", "d": ["The disaggregation of an actomyosin contractile ring into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0042129", "l": "regulation of T cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1900239", "l": "regulation of phenotypic switching", "d": ["Any process that modulates the frequency, rate or extent of phenotypic switching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905526", "l": "regulation of Golgi lumen acidification", "d": ["Any process that modulates the frequency, rate or extent of Golgi lumen acidification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006540", "l": "glutamate decarboxylation to succinate", "d": ["The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it channels glutamate into the TCA cycle bypassing two steps of that cycle. There are three enzymes involved in the GABA shunt: glutamate decarboxylase (GAD), GABA aminotransferase (GABA-TA), and succinate semialdehyde dehydrogenase (SSADH). These three enzymes acting in concert to convert glutamate into succinate. The GABA shunt is predominantly associated with neurotransmission in the mammalian brain. It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0060916", "l": "mesenchymal cell proliferation involved in lung development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031508", "l": "pericentric heterochromatin formation", "d": ["The compaction of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by methylation of histone H3K9, into heterochromatin, resulting in the repression of transcription at pericentric DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003195", "l": "tricuspid valve formation", "d": ["The developmental process pertaining to the initial formation of the tricuspid valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035744", "l": "T-helper 1 cell cytokine production", "d": ["Any process that contributes to cytokine production by a T-helper 1 cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046721", "l": "formic acid secretion", "d": ["The controlled release of formic acid, HCOOH, by a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034141", "l": "positive regulation of toll-like receptor 3 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0035303", "l": "regulation of dephosphorylation", "d": ["Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048275", "l": "N-terminal peptidyl-arginine acetylation", "d": ["The acetylation of the N-terminal arginine of proteins; catalyzed by an uncharacterized arginyl-peptide alpha-N-acetyltransferase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0120193", "l": "tight junction organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900966", "l": "negative regulation of methanophenazine metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090461", "l": "intracellular glutamate homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of glutamate within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0060191", "l": "regulation of lipase activity", "d": ["Any process that modulates the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902721", "l": "negative regulation of prolactin secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of prolactin secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0000302", "l": "response to reactive oxygen species", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032339", "l": "negative regulation of inhibin secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of inhibin from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002629", "l": "negative regulation of proteolysis associated with antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051683", "l": "establishment of Golgi localization", "d": ["The directed movement of the Golgi to a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0043062", "l": "extracellular structure organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010886", "l": "positive regulation of cholesterol storage", "d": ["Any process that increases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075203", "l": "positive regulation of penetration hypha formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1901145", "l": "mesenchymal cell apoptotic process involved in nephron morphogenesis", "d": ["Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042694", "l": "muscle cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a muscle cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021850", "l": "subpallium glioblast cell division", "d": ["The division of glioblasts in the subpallium. These cells will give rise to oligodendrocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044696", "l": "killing by virus of host cell by post-segregational killing", "d": ["The process by which a virus causes the death of daughter cells which do not contain its genes after host cell division, by a mechanism of post-segregational killing (PSK). The extrachromosomal viral DNA consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. Daughter cells that do not contain the viral extrachromosomal element are killed by the long lived toxin, while daughter cells that do contain the viral extrachromosomal element are protected by the action of the short lived antitoxin it encodes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900576", "l": "gerfelin metabolic process", "d": ["The chemical reactions and pathways involving gerfelin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019407", "l": "hexitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hexitols, any alditol with a chain of six carbon atoms in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905198", "l": "manchette assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a manchette."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.503963827996756", "identifiers": [{"i": "GO:0051445", "l": "regulation of meiotic cell cycle", "d": ["Any process that modulates the rate or extent of progression through the meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0061232", "l": "mesonephric glomerular epithelium development", "d": ["The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000411", "l": "positive regulation of transcription by galactose", "d": ["Any process involving galactose that activates or increases the rate of transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000483", "l": "endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the nuclei of D. melanogaster as well as in those of other dipteran species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0019323", "l": "pentose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901291", "l": "negative regulation of double-strand break repair via single-strand annealing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via single-strand annealing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0010526", "l": "retrotransposon silencing", "d": ["Any process that decreases the frequency, rate or extent of retrotransposition. Retrotransposons are a subset of transposable elements that use an RNA intermediate and reverse transcribe themselves into the genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140973", "l": "positive regulation of AIM2 inflammasome complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of AIM2 inflammasome complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003369", "l": "establishment of cell polarity involved in mesendodermal cell migration", "d": ["The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of a mesendodermal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900313", "l": "negative regulation of maltohexaose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maltohexaose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048207", "l": "vesicle targeting, rough ER to cis-Golgi", "d": ["The process in which vesicles are directed to specific destination membranes during transport from the rough endoplasmic reticulum to the cis-Golgi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061203", "l": "striated muscle paramyosin thick filament assembly", "d": ["The aggregation, arrangement and bonding together of proteins to form the paramyosin-based thick filaments of myofibrils in striated muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017194", "l": "N-terminal peptidyl-isoleucine acetylation", "d": ["The acetylation of the N-terminal isoleucine of proteins to form the derivative N-acetyl-L-isoleucine. The occurrence of this modification has not been confirmed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000906", "l": "positive regulation of starch metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of starch metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000074", "l": "regulation of type B pancreatic cell development", "d": ["Any process that modulates the frequency, rate or extent of pancreatic B cell development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106112", "l": "negative regulation of mitotic cohesin ssDNA (lagging strand) loading", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042195", "l": "aerobic gallate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the presence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0006000", "l": "fructose metabolic process", "d": ["The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006431", "l": "methionyl-tRNA aminoacylation", "d": ["The process of coupling methionine to methionyl-tRNA, catalyzed by methionyl-tRNA synthetase. The methionyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a methionine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061724", "l": "lipophagy", "d": ["The selective autophagy process in which lipid droplets are delivered to the vacuole and degraded in response to changing cellular conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0021879", "l": "forebrain neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009140", "l": "pyrimidine nucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061325", "l": "cell proliferation involved in outflow tract morphogenesis", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048213", "l": "Golgi vesicle prefusion complex stabilization", "d": ["The binding of specific proteins to the t-SNARE/v-SNARE/SNAP25 complex, by which the Golgi vesicle prefusion complex is stabilized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0007487", "l": "analia development", "d": ["The process whose specific outcome is the progression of the analia over time, from its formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia development in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060167", "l": "regulation of adenosine receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0071772", "l": "response to BMP", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018151", "l": "peptide cross-linking via L-histidyl-L-tyrosine", "d": ["The modification of peptidyl-histidine and peptidyl-tyrosine to form a protein cross-link."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0034367", "l": "protein-containing complex remodeling", "d": ["The acquisition, loss, or modification of macromolecules within a complex, resulting in the alteration of an existing complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042125", "l": "protein galactosylation", "d": ["The addition of a galactose molecule to a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0060292", "l": "long-term synaptic depression", "d": ["A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900325", "l": "negative regulation of maltotriulose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maltotriulose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140889", "l": "DNA replication-dependent chromatin disassembly", "d": ["The disruption of nucleosomes during DNA replication to allow the replication machinery to access the DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0050977", "l": "magnetoreception by sensory perception of chemical stimulus", "d": ["The series of events required for an organism to receive a chemical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. It is believed that organisms such as birds and salamanders use a 'chemical compass': chemical reactions that involve transitions between different spin states can be influenced by magnetic fields and by detecting the different product ratios, these organisms can perceive the direction of the magnetic field. The mechanism by which this is detected is not certain but it may also involve light stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901593", "l": "response to GW 7647", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046760", "l": "viral budding from Golgi membrane", "d": ["A viral budding that starts with formation of a membrane curvature in the host Golgi membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1902435", "l": "regulation of male mating behavior", "d": ["Any process that modulates the frequency, rate or extent of male mating behavior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042892", "l": "chloramphenicol transmembrane transport", "d": ["The directed movement of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000087", "l": "regulation of mesonephric glomerulus development", "d": ["Any process that modulates the frequency, rate or extent of mesonephric glomerulus development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075308", "l": "negative regulation of conidium formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904044", "l": "response to aldosterone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0075509", "l": "endocytosis involved in viral entry into host cell", "d": ["Any endocytosis that is involved in the uptake of a virus into a host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.652601755204856", "identifiers": [{"i": "GO:0007588", "l": "excretion", "d": ["The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035219", "l": "prothoracic disc development", "d": ["Progression of the prothoracic disc over time, from its initial formation through to its metamorphosis to form the adult humerous and anterior spiracle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030199", "l": "collagen fibril organization", "d": ["Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048345", "l": "regulation of paraxial mesodermal cell fate determination", "d": ["Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000186", "l": "negative regulation of phosphate transmembrane transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0048137", "l": "spermatocyte division", "d": ["The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035871", "l": "protein K11-linked deubiquitination", "d": ["A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers, is removed from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002123", "l": "irritable aggressive behavior", "d": ["Aggressive behavior induced by frustration and directed against an available target."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018877", "l": "beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process", "d": ["The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0033304", "l": "chlorophyll a metabolic process", "d": ["The chemical reactions and pathways involving chlorophyll a."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002826", "l": "negative regulation of T-helper 1 type immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a T-helper 1 type immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.675373588411375", "identifiers": [{"i": "GO:0035850", "l": "epithelial cell differentiation involved in kidney development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009148", "l": "pyrimidine nucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006640", "l": "monoacylglycerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010831", "l": "positive regulation of myotube differentiation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035353", "l": "nicotinamide mononucleotide transmembrane transport", "d": ["The process in which nicotinamide mononucleotide is transported across a membrane. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0017185", "l": "peptidyl-lysine hydroxylation", "d": ["The hydroxylation of peptidyl-lysine to form peptidyl-hydroxylysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061198", "l": "fungiform papilla formation", "d": ["The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.232064878529073", "identifiers": [{"i": "GO:0048103", "l": "somatic stem cell division", "d": ["The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036150", "l": "phosphatidylserine acyl-chain remodeling", "d": ["Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation reactions, to generate phosphatidylserine containing different types of fatty acid acyl chains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0033078", "l": "extrathymic T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway independent of the thymus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900398", "l": "negative regulation of pyrimidine nucleotide biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pyrimidine nucleotide biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.210428088592487", "identifiers": [{"i": "GO:0010468", "l": "regulation of gene expression", "d": ["Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003327", "l": "type B pancreatic cell fate commitment", "d": ["The commitment of a cell to a type B pancreatic cell fate and its capacity to differentiate into a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048756", "l": "sieve cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a sieve cell. A sieve cell is a type of sieve element that has relatively undifferentiated sieve areas (with narrow pores). The sieve areas are rather uniform in structure on all walls; that is, there are no sieve plates. Typical of gymnosperms and lower vascular plants. The sieve element is the cell in the phloem tissue concerned with mainly longitudinal conduction of food materials."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.465174152298118", "identifiers": [{"i": "GO:0061013", "l": "regulation of mRNA catabolic process", "d": ["Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018946", "l": "aerobic organosilicon metabolic process", "d": ["The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the presence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905599", "l": "positive regulation of low-density lipoprotein receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of low-density lipoprotein receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070301", "l": "cellular response to hydrogen peroxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0043943", "l": "regulation of asexual sporulation resulting in formation of a cellular spore", "d": ["Any process that modulates the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901739", "l": "regulation of myoblast fusion", "d": ["Any process that modulates the frequency, rate or extent of myoblast fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900722", "l": "regulation of protein adenylylation", "d": ["Any process that modulates the frequency, rate or extent of protein adenylylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061987", "l": "negative regulation of transcription from RNA polymerase II promoter by glucose", "d": ["Any process involving glucose that decreases the frequency, rate or extent or transcription from an RNA polymerase II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034276", "l": "kynurenic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.024910309174537", "identifiers": [{"i": "GO:0009890", "l": "negative regulation of biosynthetic process", "d": ["Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.533178747620099", "identifiers": [{"i": "GO:0048585", "l": "negative regulation of response to stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046202", "l": "cyanide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0098510", "l": "sensory perception of high humidity", "d": ["The series of events required for an organism to detect high environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006178", "l": "guanine salvage", "d": ["Any process that generates guanine, 2-amino-6-hydroxypurine, from derivatives of it without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.824318789188837", "identifiers": [{"i": "GO:0072524", "l": "pyridine-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0061118", "l": "regulation of positive chemotaxis to cAMP", "d": ["Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0045744", "l": "negative regulation of G protein-coupled receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110043", "l": "positive regulation of pharynx morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of pharynx morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006018", "l": "2-deoxyribose 1-phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002738", "l": "positive regulation of plasmacytoid dendritic cell cytokine production", "d": ["Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019608", "l": "nicotine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046380", "l": "N-acetylneuraminate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.851035922319305", "identifiers": [{"i": "GO:0051249", "l": "regulation of lymphocyte activation", "d": ["Any process that modulates the frequency, rate or extent of lymphocyte activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070155", "l": "mitochondrial methionyl-tRNA aminoacylation", "d": ["The process of coupling methionine to methionyl-tRNA in a mitochondrion, catalyzed by methionyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090337", "l": "regulation of formin-nucleated actin cable assembly", "d": ["Any process that modulates the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035992", "l": "tendon formation", "d": ["The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905247", "l": "positive regulation of aspartic-type peptidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of aspartic-type peptidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0002225", "l": "positive regulation of antimicrobial peptide production", "d": ["Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097026", "l": "dendritic cell dendrite assembly", "d": ["Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0006074", "l": "(1->3)-beta-D-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010030", "l": "positive regulation of seed germination", "d": ["Any process that activates or increase the rate of seed germination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.954478501509683", "identifiers": [{"i": "GO:0048705", "l": "skeletal system morphogenesis", "d": ["The process in which the anatomical structures of the skeleton are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070349", "l": "positive regulation of brown fat cell proliferation", "d": ["Any process that activates or increases the rate or extent of brown fat cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060314", "l": "regulation of ryanodine-sensitive calcium-release channel activity", "d": ["Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0060294", "l": "cilium movement involved in cell motility", "d": ["Movement of cilia mediated by motor proteins that contributes to the movement of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0045911", "l": "positive regulation of DNA recombination", "d": ["Any process that activates or increases the frequency, rate or extent of DNA recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901203", "l": "positive regulation of extracellular matrix assembly", "d": ["Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0061053", "l": "somite development", "d": ["The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904575", "l": "positive regulation of selenocysteine insertion sequence binding", "d": ["Any process that activates or increases the frequency, rate or extent of selenocysteine insertion sequence binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0051452", "l": "intracellular pH reduction", "d": ["Any process that reduces the internal pH of a cell, measured by the concentration of the hydrogen ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0030186", "l": "melatonin metabolic process", "d": ["The chemical reactions and pathways involving melatonin (N-acetyl-5-methoxytryptamine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043485", "l": "endosome to pigment granule transport", "d": ["The directed movement of substances from endosomes to pigment granules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001938", "l": "positive regulation of endothelial cell proliferation", "d": ["Any process that activates or increases the rate or extent of endothelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060642", "l": "white fat cell differentiation involved in mammary gland fat development", "d": ["The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009805", "l": "coumarin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of coumarins, a class of compounds derived from the phenylacrylic skeleton of cinnamic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098971", "l": "anterograde dendritic transport of neurotransmitter receptor complex", "d": ["The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160037", "l": "negative regulation of postsynaptic density assembly", "d": ["Any process that decreases the rate, frequency, or extent of postsynaptic density assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903236", "l": "regulation of leukocyte tethering or rolling", "d": ["Any process that modulates the frequency, rate or extent of leukocyte tethering or rolling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0006450", "l": "regulation of translational fidelity", "d": ["Any process that modulates the ability of the translational apparatus to interpret the genetic code."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.06379513530257", "identifiers": [{"i": "GO:0044272", "l": "sulfur compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009859", "l": "pollen hydration", "d": ["The process in which water is taken up by pollen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:1905777", "l": "regulation of exonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of exonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903528", "l": "regulation of dCDP biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of dCDP biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045900", "l": "negative regulation of translational elongation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006615", "l": "SRP-dependent cotranslational protein targeting to membrane, docking", "d": ["The process in which an SRP-bound ribosome forms a complex with the SRP receptor in the ER membrane, allowing the ribosome to bind to the membrane, during cotranslational membrane targeting."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060015", "l": "granulosa cell fate commitment", "d": ["The cell fate commitment of precursor cells that will become granulosa cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903267", "l": "negative regulation of ornithine catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ornithine catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1900733", "l": "negative regulation of polyketide biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of polyketide biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002811", "l": "negative regulation of antifungal peptide biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.905555711669919", "identifiers": [{"i": "GO:0031047", "l": "regulatory ncRNA-mediated gene silencing", "d": ["A process in which an regulatory non-coding RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904194", "l": "positive regulation of cholangiocyte apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006647", "l": "phosphatidyl-N-monomethylethanolamine biosynthetic process", "d": ["The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000440", "l": "regulation of toll-like receptor 15 signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of toll-like receptor 15 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.003741351937961", "identifiers": [{"i": "GO:0048839", "l": "inner ear development", "d": ["The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0006563", "l": "L-serine metabolic process", "d": ["The chemical reactions and pathways involving L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010584", "l": "pollen exine formation", "d": ["The formation of the pollen exine. The reticulate pollen wall pattern consists of two layers, exine and intine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000071", "l": "regulation of defense response by callose deposition", "d": ["Any process that modulates the frequency, rate or extent of defense response by callose deposition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032610", "l": "interleukin-1 alpha production", "d": ["The appearance of interleukin-1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021838", "l": "motogenic signaling involved in interneuron migration from the subpallium to the cortex", "d": ["The creation and reception of signals that result in the directional movement of interneuron precursors from the subpallium to the cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060709", "l": "glycogen cell differentiation involved in embryonic placenta development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045226", "l": "extracellular polysaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polysaccharides used in extracellular structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030805", "l": "regulation of cyclic nucleotide catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cyclic nucleotides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060019", "l": "radial glial cell differentiation", "d": ["The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021982", "l": "pineal gland development", "d": ["The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051413", "l": "response to cortisone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001310", "l": "gliotoxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071831", "l": "intermediate-density lipoprotein particle clearance", "d": ["The process in which a intermediate-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097039", "l": "protein linear polyubiquitination", "d": ["A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is added to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018226", "l": "peptidyl-S-farnesyl-L-cysteine biosynthetic process from peptidyl-cysteine", "d": ["The modification of peptidyl-cysteine to form peptidyl-S-farnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine; the residue may be found at the first position in the sequence motif C-X-X-(SAQCMT)* where the second and third positions are usually aliphatic."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0070167", "l": "regulation of biomineral tissue development", "d": ["Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051058", "l": "negative regulation of small GTPase mediated signal transduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of small GTPase mediated signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0031113", "l": "regulation of microtubule polymerization", "d": ["Any process that modulates the frequency, rate or extent of microtubule polymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000651", "l": "positive regulation of sodium ion transmembrane transporter activity", "d": ["Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905490", "l": "negative regulation of sensory neuron axon guidance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sensory neuron axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0097048", "l": "dendritic cell apoptotic process", "d": ["Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0000018", "l": "regulation of DNA recombination", "d": ["Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002589", "l": "regulation of antigen processing and presentation of peptide antigen via MHC class I", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1901523", "l": "icosanoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of icosanoid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:2000762", "l": "regulation of phenylpropanoid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of phenylpropanoid metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002620", "l": "negative regulation of non-professional antigen presenting cell antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1990186", "l": "regulation of lymphatic vessel size", "d": ["Any process that modulates the size of lymphatic vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046206", "l": "trypanothione metabolic process", "d": ["The chemical reactions and pathways involving trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000903", "l": "cellooligosaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a cellooligosaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900121", "l": "negative regulation of receptor binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110166", "l": "DNA synthesis involved in mitochondrial DNA replication", "d": ["Any DNA biosynthetic process that is involved in mitochondrial DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015823", "l": "phenylalanine transport", "d": ["The directed movement of phenylalanine, 2-amino-3-phenylpropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902927", "l": "inulin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of inulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035540", "l": "positive regulation of SNARE complex disassembly", "d": ["Any process that increases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072554", "l": "blood vessel lumenization", "d": ["The process in which a developing blood vessel forms an endothelial lumen through which blood will flow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1901984", "l": "negative regulation of protein acetylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:1905819", "l": "negative regulation of chromosome separation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chromosome separation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990625", "l": "negative regulation of cytoplasmic translational initiation in response to stress", "d": ["Any process that stops, prevents or reduces the rate of cytoplasmic translation initiation as a result of a stimulus indicating the organism is under stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060060", "l": "post-embryonic retina morphogenesis in camera-type eye", "d": ["The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the post-embryonic life stage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070462", "l": "plus-end specific microtubule depolymerization", "d": ["The removal of tubulin heterodimers from the plus end of a microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904470", "l": "regulation of endothelin production", "d": ["Any process that modulates the frequency, rate or extent of endothelin production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044127", "l": "regulation of development of symbiont in host", "d": ["Any process in which the symbiont regulates its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901769", "l": "carbapenem biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of carbapenem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044029", "l": "positive regulation of gene expression via CpG island demethylation", "d": ["An epigenetic gene regulation mechanism that positively regulates gene expression by demethylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0015878", "l": "biotin transport", "d": ["The directed movement of biotin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072015", "l": "podocyte development", "d": ["The process whose specific outcome is the progression of a glomerular visceral epithelial cell over time, from its formation to the mature structure. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902328", "l": "bacterial-type DNA replication initiation", "d": ["Any DNA replication initiation that is involved in bacterial-type DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900451", "l": "positive regulation of glutamate receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0060295", "l": "regulation of cilium movement involved in cell motility", "d": ["Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110099", "l": "negative regulation of calcium import into the mitochondrion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071487", "l": "cellular response to low light intensity stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051940", "l": "regulation of catecholamine uptake involved in synaptic transmission", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034720", "l": "histone H3-K4 demethylation", "d": ["The modification of histone H3 by the removal of a methyl group from lysine at position 4 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015680", "l": "protein maturation by copper ion transfer", "d": ["A process that contributes to the delivery of copper ions to a target protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904150", "l": "negative regulation of microglial cell mediated cytotoxicity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell mediated cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043622", "l": "cortical microtubule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cell cortex, i.e. just beneath the plasma membrane of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900247", "l": "regulation of cytoplasmic translational elongation", "d": ["Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0021795", "l": "cerebral cortex cell migration", "d": ["The orderly movement of cells from one site to another in the cerebral cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0002249", "l": "lymphocyte anergy", "d": ["Any process contributing to lymphocyte anergy, a state of functional inactivation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097184", "l": "response to azide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021998", "l": "neural plate mediolateral regionalization", "d": ["The process that regulates the coordinated growth and differentiation that establishes the non-random mediolateral spatial arrangement of the neural plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.523519163150823", "identifiers": [{"i": "GO:0009306", "l": "protein secretion", "d": ["The controlled release of proteins from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0019835", "l": "cytolysis", "d": ["The rupture of cell membranes and the loss of cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046676", "l": "negative regulation of insulin secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043497", "l": "regulation of protein heterodimerization activity", "d": ["Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035606", "l": "peptidyl-cysteine S-trans-nitrosylation", "d": ["Transfer of a nitric oxide (NO) group from one cysteine residue to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072343", "l": "pancreatic stellate cell proliferation", "d": ["The multiplication or reproduction of pancreatic stellate cells, resulting in the expansion of a pancreatic stellate cell population. Pancreatic stellate cells are found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and have long cytoplasmic processes that encircle the base of the acinus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033611", "l": "oxalate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of oxalate, the organic acid ethanedioate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035732", "l": "nitric oxide storage", "d": ["The accumulation and maintenance in cells or tissues of nitric oxide (NO). Nitric oxide is stored in the form of dinitrosyl-iron complexes, which are stabilized, and possibly sequestered, by binding to glutathione S-transferase proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072704", "l": "response to mercaptoethanol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045586", "l": "regulation of gamma-delta T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of gamma-delta T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046031", "l": "ADP metabolic process", "d": ["The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003253", "l": "cardiac neural crest cell migration involved in outflow tract morphogenesis", "d": ["The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0006311", "l": "meiotic gene conversion", "d": ["The cell cycle process in which genetic information is transferred from one helix to another. It often occurs in association with general genetic recombination events, and is believed to be a straightforward consequence of the mechanisms of general recombination and DNA repair. For example, meiosis might yield three copies of the maternal version of an allele and only one copy of the paternal allele, indicating that one of the two copies of the paternal allele has been changed to a copy of the maternal allele."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141063", "l": "epigenetic programming in the central cell", "d": ["The establishment of epigenetic modifications (imprints) in a plant central cell, leading to an asymmetry between the two maternal alleles and the paternal allele, and differential expression of the corresponding alleles in the developing endosperm. This can happen through heterochromatin formation or differential chromatin loop formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.071082486141265", "identifiers": [{"i": "GO:0060235", "l": "lens induction in camera-type eye", "d": ["Signaling at short range between the head ectoderm and the optic vesicle that results in the head ectoderm forming a lens."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032265", "l": "XMP salvage", "d": ["Any process which produces xanthosine monophosphate from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904250", "l": "positive regulation of age-related resistance", "d": ["Any process that activates or increases the extent of age-related resistance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901540", "l": "ent-pimara-8(14),15-diene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ent-pimara-8(14),15-diene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0036490", "l": "regulation of translation in response to endoplasmic reticulum stress", "d": ["Modulation of the frequency, rate or extent of translation as a result of endoplasmic reticulum stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900276", "l": "regulation of proteinase activated receptor activity", "d": ["Any process that modulates the frequency, rate or extent of proteinase activated receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901147", "l": "mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis", "d": ["Any mesenchymal cell apoptotic process that is involved in metanephric nephron morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0039671", "l": "evasion by virus of host natural killer cell activity", "d": ["Any process by which a virus avoids the effects mediated by the host organism's natural killer (NK) cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904694", "l": "negative regulation of vascular associated smooth muscle contraction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031443", "l": "fast-twitch skeletal muscle fiber contraction", "d": ["A process in which force is generated within fast-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fast-twitch skeletal muscle is characterized by fast time parameters, high force development and fatiguability."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0001964", "l": "startle response", "d": ["An action or movement due to the application of a sudden unexpected stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072271", "l": "metanephric short descending thin limb development", "d": ["The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903720", "l": "negative regulation of I-kappaB phosphorylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of I-kappaB phosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901141", "l": "regulation of lignin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of lignin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030164", "l": "protein denaturation", "d": ["Structural change in proteins which destroys the native, active configuration without rupture of peptide bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0051204", "l": "protein insertion into mitochondrial membrane", "d": ["The process that results in the incorporation of a protein into a mitochondrial membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904503", "l": "negative regulation of lipophagy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lipophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090227", "l": "regulation of red or far-red light signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010614", "l": "negative regulation of cardiac muscle hypertrophy", "d": ["Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0002517", "l": "T cell tolerance induction", "d": ["A process involving any mechanism for tolerance induction in T cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902959", "l": "regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0008614", "l": "pyridoxine metabolic process", "d": ["The chemical reactions and pathways involving pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0043611", "l": "isoprene metabolic process", "d": ["The chemical reactions and pathways involving isoprene, C5H8."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.741814295060699", "identifiers": [{"i": "GO:0014070", "l": "response to organic cyclic compound", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097499", "l": "protein localization to non-motile cilium", "d": ["A process in which a protein is transported to, or maintained in, a location within a non-motile cilium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002454", "l": "peripheral B cell deletion", "d": ["The deletion of B cells by apoptotic process occurring as part of peripheral tolerance induction and B cell selection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2001119", "l": "methanofuran metabolic process", "d": ["The chemical reactions and pathways involving a methanofuran."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902978", "l": "premeiotic DNA replication termination", "d": ["Any DNA replication termination involved in meiotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098962", "l": "regulation of postsynaptic neurotransmitter receptor activity", "d": ["Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902618", "l": "cellular response to fluoride", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0050935", "l": "iridophore differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an iridophore. Iridophores are pigment cells derived from the neural crest. They contain guanidine or other purine crystals deposited in stacks called reflecting platets or iridisomes. This gives them a silver, gold, or iridescent appearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0007314", "l": "oocyte anterior/posterior axis specification", "d": ["Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031641", "l": "regulation of myelination", "d": ["Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072251", "l": "metanephric juxtaglomerulus cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the metanephros as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0046463", "l": "acylglycerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901156", "l": "neomycin metabolic process", "d": ["The chemical reactions and pathways involving neomycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110063", "l": "positive regulation of angiotensin-activated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the angiotensin-activated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000736", "l": "double-strand break repair via single-strand annealing, removal of nonhomologous ends", "d": ["During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035292", "l": "specification of segmental identity, trunk", "d": ["The specification of the characteristic structures of trunk segments, following establishment of segment boundaries. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051551", "l": "aurone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aurones, a series of yellow plant pigments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.281967957033203", "identifiers": [{"i": "GO:0022413", "l": "reproductive process in single-celled organism", "d": ["A process, occurring at the cellular level, that is involved in the reproductive function of a single-celled organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902308", "l": "regulation of peptidyl-serine dephosphorylation", "d": ["Any process that modulates the frequency, rate or extent of peptidyl-serine dephosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900129", "l": "positive regulation of G-protein activated inward rectifier potassium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071946", "l": "cis-acting DNA replication termination", "d": ["A DNA replication termination process that is initiated by protein binding to a binding site on the same chromosome, but remote from the termination site, via DNA looping or chromosome kissing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010773", "l": "meiotic DNA recombinase assembly involved in meiotic gene conversion", "d": ["The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000631", "l": "regulation of pre-miRNA processing", "d": ["Any process that modulates the frequency, rate or extent of pre-microRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021566", "l": "hypoglossal nerve development", "d": ["The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.32568854542945", "identifiers": [{"i": "GO:0031328", "l": "positive regulation of cellular biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:1905477", "l": "positive regulation of protein localization to membrane", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0015822", "l": "ornithine transport", "d": ["The directed movement of ornithine, 2,5-diaminopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900739", "l": "regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.161881760686384", "identifiers": [{"i": "GO:0045814", "l": "negative regulation of gene expression, epigenetic", "d": ["An epigenetic process that silences gene expression at specific genomic regions through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or the cytosine DNA methylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901512", "l": "(-)-microperfuranone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (-)-microperfuranone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043180", "l": "rhythmic inhibition", "d": ["Any process involved in the generation of rhythmic, synchronous inhibitory synaptic inputs in a neural circuit."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0043410", "l": "positive regulation of MAPK cascade", "d": ["Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006370", "l": "7-methylguanosine mRNA capping", "d": ["Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033027", "l": "positive regulation of mast cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate, or extent of mast cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000940", "l": "negative regulation of plant-type cell wall cellulose catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000020", "l": "positive regulation of male gonad development", "d": ["Any process that activates or increases the frequency, rate or extent of male gonad development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090094", "l": "metanephric cap mesenchymal cell proliferation involved in metanephros development", "d": ["The multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901389", "l": "negative regulation of transforming growth factor beta activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0051593", "l": "response to folic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901786", "l": "p-cresol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of p-cresol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036257", "l": "multivesicular body organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a multivesicular body. A multivesicular body is a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903218", "l": "regulation of malate dehydrogenase (decarboxylating) (NADP+) activity", "d": ["Any process that modulates the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071413", "l": "cellular response to hydroxyisoflavone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0042073", "l": "intraciliary transport", "d": ["The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006884", "l": "cell volume homeostasis", "d": ["Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051676", "l": "pullulan metabolic process", "d": ["The chemical reactions and pathways involving pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0006511", "l": "ubiquitin-dependent protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035366", "l": "negative regulation of thymine transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060412", "l": "ventricular septum morphogenesis", "d": ["The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002326", "l": "B cell lineage commitment", "d": ["The process in which a lymphoid progenitor cell becomes committed to become any type of B cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021564", "l": "vagus nerve development", "d": ["The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009661", "l": "chromoplast organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chromoplast. A chromoplast is a plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015836", "l": "lipid-linked peptidoglycan transport", "d": ["The directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001210", "l": "regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway", "d": ["Any process that modulates the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903301", "l": "positive regulation of hexokinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of hexokinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062196", "l": "regulation of lysosome size", "d": ["Any process that modulates the size of a lysosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003011", "l": "involuntary skeletal muscle contraction", "d": ["A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Involuntary skeletal muscle is skeletal muscle that is not under conscious control."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902199", "l": "3-methylbut-2-enoyl-CoA(4-) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-methylbut-2-enoyl-CoA(4-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099577", "l": "regulation of translation at presynapse, modulating synaptic transmission", "d": ["Any process that modulates synaptic transmission by regulating translation occurring at the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0019693", "l": "ribose phosphate metabolic process", "d": ["The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904449", "l": "negative regulation of aspartate secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aspartate secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031848", "l": "protection from non-homologous end joining at telomere", "d": ["A process that prevents non-homologous end joining at telomere, thereby ensuring that telomeres do not fuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018294", "l": "protein-FAD linkage via S-(8alpha-FAD)-L-cysteine", "d": ["The formation of a protein-FAD linkage via S-(8-alpha-FAD)-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061373", "l": "mammillary axonal complex development", "d": ["The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070730", "l": "cAMP transport", "d": ["The directed movement of cyclic AMP (cAMP), into, out of or within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035225", "l": "determination of genital disc primordium", "d": ["Allocation of embryonic cells to the genital imaginal disc founder populations. Early in development at the blastoderm stage, the anlage of the genital disc of both sexes consists of three primordia: the female genital primoridum lcoated anteriorly, the anal primoridum located posteriorly, and the male gential primordium between the two."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0018149", "l": "peptide cross-linking", "d": ["The formation of a covalent cross-link between or within protein chains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061413", "l": "regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source", "d": ["A transcription regulation process in which the presence of a nonfermentable carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:1990179", "l": "protein localization to actomyosin contractile ring", "d": ["A process in which a protein is transported to, or maintained at, the actomyosin contractile ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900191", "l": "negative regulation of single-species biofilm formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070413", "l": "trehalose metabolism in response to stress", "d": ["The chemical reactions and pathways involving trehalose that occur as a result of a stimulus indicating the organism is under stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0032963", "l": "collagen metabolic process", "d": ["The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0050746", "l": "regulation of lipoprotein metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035830", "l": "palmatine metabolic process", "d": ["The chemical reactions and pathways involving palmatine, a berberine alkaloid found in many plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006190", "l": "inosine salvage", "d": ["Any process that generates inosine, hypoxanthine riboside, from derivatives of it without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000843", "l": "regulation of testosterone secretion", "d": ["Any process that modulates the frequency, rate or extent of testosterone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015952", "l": "purine deoxyribonucleotide interconversion", "d": ["The chemical reactions and pathways by which a purine deoxyribonucleotide is synthesized from another purine deoxyribonucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018284", "l": "iron incorporation into protein via tetrakis-L-cysteinyl iron", "d": ["The incorporation of iron into a protein via tetrakis-L-cysteinyl iron (there is no exogenous sulfur, so this modification by itself does not produce an iron-sulfur protein)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901090", "l": "regulation of protein tetramerization", "d": ["Any process that modulates the frequency, rate or extent of protein tetramerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0052320", "l": "positive regulation of phytoalexin metabolic process", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0000103", "l": "sulfate assimilation", "d": ["The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990591", "l": "asparagine transmembrane import into vacuole", "d": ["The directed movement of asparagine into the vacuole across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015859", "l": "intracellular nucleoside transport", "d": ["The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.018719038236206", "identifiers": [{"i": "GO:0007601", "l": "visual perception", "d": ["The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033368", "l": "protease localization to mast cell secretory granule", "d": ["Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a mast cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902655", "l": "aromatic primary alcohol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aromatic primary alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000263", "l": "regulation of blood coagulation, extrinsic pathway", "d": ["Any process that modulates the frequency, rate or extent of blood coagulation, extrinsic pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0050810", "l": "regulation of steroid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900640", "l": "regulation of austinol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of austinol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903816", "l": "positive regulation of collecting lymphatic vessel constriction", "d": ["Any process that activates or increases the frequency, rate or extent of collecting lymphatic vessel constriction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.594043123901756", "identifiers": [{"i": "GO:0030866", "l": "cortical actin cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of actin-based cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0090667", "l": "cell chemotaxis to vascular endothelial growth factor", "d": ["The directed movement of a motile cell in response to the presence of vascular endothelial growth factor (VEGF)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035911", "l": "descending aorta morphogenesis", "d": ["The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090674", "l": "endothelial cell-matrix adhesion via fibronectin", "d": ["The binding of an endothelial cell to the extracellular matrix via fibronectin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033031", "l": "positive regulation of neutrophil apoptotic process", "d": ["Any process that activates or increases the frequency, rate, or extent of neutrophil apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0032245", "l": "regulation of purine nucleoside transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903870", "l": "positive regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity", "d": ["Any process that activates or increases the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000705", "l": "regulation of dense core granule biogenesis", "d": ["Any process that modulates the frequency, rate or extent of dense core granule biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0120109", "l": "mitotic telomere clustering and tethering at nuclear periphery", "d": ["The process in which the telomeres are gathered together to a small number of foci per chromosome (usually one per chromosome or fewer), and moved to and tethered at the nuclear periphery, as part of a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033329", "l": "kaempferol O-glucoside metabolic process", "d": ["The chemical reactions and pathways involving O-glucosylated derivatives of kaempferol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0048278", "l": "vesicle docking", "d": ["The initial attachment of a transport vesicle membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905227", "l": "negative regulation of adhesion of symbiont to host epithelial cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of adhesion of symbiont to host epithelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900280", "l": "negative regulation of CD4-positive, alpha-beta T cell costimulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090295", "l": "nitrogen catabolite repression of transcription", "d": ["A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900730", "l": "negative regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035984", "l": "cellular response to trichostatin A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000473", "l": "maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)", "d": ["Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032324", "l": "molybdopterin cofactor biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007318", "l": "pole plasm protein localization", "d": ["Any process in which a protein is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000348", "l": "mRNA branch site recognition", "d": ["Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0042441", "l": "eye pigment metabolic process", "d": ["The chemical reactions and pathways involving eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010885", "l": "regulation of cholesterol storage", "d": ["Any process that modulates the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901664", "l": "regulation of NAD+ ADP-ribosyltransferase activity", "d": ["Any process that modulates the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0044396", "l": "actin cortical patch organization", "d": ["A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane in cells, at sites of endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034164", "l": "negative regulation of toll-like receptor 9 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 9 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0030195", "l": "negative regulation of blood coagulation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901956", "l": "positive regulation of retrograde dense core granule transport", "d": ["Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.60527870462187", "identifiers": [{"i": "GO:1901564", "l": "organonitrogen compound metabolic process", "d": ["The chemical reactions and pathways involving organonitrogen compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901884", "l": "4-hydroxycoumarin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 4-hydroxycoumarin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0098725", "l": "symmetric cell division", "d": ["Cell division in which both daughter cells are of the same type."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.235375449259656", "identifiers": [{"i": "GO:0030334", "l": "regulation of cell migration", "d": ["Any process that modulates the frequency, rate or extent of cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903972", "l": "regulation of cellular response to macrophage colony-stimulating factor stimulus", "d": ["Any process that modulates the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904901", "l": "positive regulation of myosin II filament organization", "d": ["Any process that activates or increases the frequency, rate or extent of myosin II filament organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904138", "l": "positive regulation of convergent extension involved in notochord morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of convergent extension involved in notochord morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900314", "l": "positive regulation of maltohexaose transport", "d": ["Any process that activates or increases the frequency, rate or extent of maltohexaose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000497", "l": "positive regulation of cell proliferation involved in compound eye morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010438", "l": "cellular response to sulfur starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902428", "l": "negative regulation of water channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of water channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048860", "l": "glioblast division", "d": ["The process resulting in the physical partitioning and separation of a glioblast into daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018425", "l": "O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of O3-(N-acetylglucosamine-1-phosphoryl)-L-serine. The recovery of O-phosphorylserine from acid hydrolysates suggests N-acetylglucosamine-1-phosphate residues are esterified to peptidyl serines through phosphoester bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000090", "l": "regulation of mesonephric glomerular mesangial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016133", "l": "brassinosteroid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904281", "l": "positive regulation of transcription by RNA polymerase V", "d": ["Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase V."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036112", "l": "medium-chain fatty-acyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with an aliphatic tail of 6 to 12 carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007479", "l": "leg disc proximal/distal pattern formation", "d": ["The establishment, maintenance and elaboration of the proximal/distal axis of the leg imaginal disc, a precursor to the adult leg."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046594", "l": "maintenance of pole plasm mRNA location", "d": ["The process of maintaining mRNA in a specific location in the oocyte pole plasm. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904171", "l": "negative regulation of bleb assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071524", "l": "pyrrolysine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903684", "l": "regulation of border follicle cell migration", "d": ["Any process that modulates the frequency, rate or extent of border follicle cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0046578", "l": "regulation of Ras protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of Ras protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075243", "l": "oospore formation", "d": ["The process in which male and female gametangia develop and fuse to form an oospore, a thick-walled resting spore of Oomycetes and certain algae and fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903811", "l": "L-asparagine import across plasma membrane", "d": ["The directed movement of L-asparagine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061070", "l": "female urethra development", "d": ["The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021759", "l": "globus pallidus development", "d": ["The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.334564020807861", "identifiers": [{"i": "GO:0006796", "l": "phosphate-containing compound metabolic process", "d": ["The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905558", "l": "negative regulation of mitotic nuclear envelope disassembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0072599", "l": "establishment of protein localization to endoplasmic reticulum", "d": ["The directed movement of a protein to a specific location in the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.282738951573606", "identifiers": [{"i": "GO:0099177", "l": "regulation of trans-synaptic signaling", "d": ["Any process that modulates the frequency, rate or extent of trans-synaptic signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032830", "l": "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0051666", "l": "actin cortical patch localization", "d": ["Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044544", "l": "envenomation resulting in plasminogen activation in another organism", "d": ["The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of plasminogen into plasmin in the bitten organism. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071582", "l": "negative regulation of zinc ion transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042686", "l": "regulation of cardioblast cell fate specification", "d": ["Any process that mediates the specification of a cell into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039701", "l": "microtubule-dependent intracellular transport of viral material towards cell periphery", "d": ["The directed movement of the viral genome or a viral particle towards the cell periphery using host microtubules. Mostly used by viruses that replicate their genome near or in the nucleus to allows newly assembled viral progeny to reach the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0007354", "l": "zygotic determination of anterior/posterior axis, embryo", "d": ["The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901673", "l": "regulation of mitotic spindle assembly", "d": ["Any process that modulates the frequency, rate or extent of mitotic spindle assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.261443428098588", "identifiers": [{"i": "GO:0019954", "l": "asexual reproduction", "d": ["A type of reproduction in which new individuals are produced from a single organism, either from an unfertilized egg or from a single cell or group of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007510", "l": "cardioblast cell fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into a cardioblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048701", "l": "embryonic cranial skeleton morphogenesis", "d": ["The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.235616146829116", "identifiers": [{"i": "GO:0032368", "l": "regulation of lipid transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045124", "l": "regulation of bone resorption", "d": ["Any process that modulates the frequency, rate or extent of bone tissue loss (resorption)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0045844", "l": "positive regulation of striated muscle tissue development", "d": ["Any process that activates or increases the frequency, rate or extent of striated muscle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002605", "l": "negative regulation of dendritic cell antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905663", "l": "positive regulation of telomerase RNA reverse transcriptase activity", "d": ["Any process that activates or increases the frequency, rate or extent of telomerase RNA reverse transcriptase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905236", "l": "cellular response to quercetin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050745", "l": "peptide cross-linking via L-cysteinyl-5-imidazolinone glycine", "d": ["The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, a cysteine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905690", "l": "nucleus disassembly", "d": ["The disaggregation of a nucleus into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902206", "l": "negative regulation of interleukin-2-mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-2-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150101", "l": "regulation of microtubule anchoring at centrosome", "d": ["Any process that modulates the frequency, rate or extent of microtubule anchoring at centrosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052096", "l": "formation of syncytium involving giant cell for nutrient acquisition", "d": ["The assembly of a syncytium, a multi-nucleate and physiologically active aggregation of fused root cells induced by a symbiotic nematode in a plant host. The syncytium exclusively provides the nematode with nourishment during its sedentary life, for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001277", "l": "negative regulation of leucine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leucine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061518", "l": "microglial cell proliferation", "d": ["The expansion of a microglial cell population by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0061107", "l": "seminal vesicle development", "d": ["The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0044577", "l": "xylose catabolic process to ethanol", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of xylose, an aldopentose, where one of the resulting products is ethanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033298", "l": "contractile vacuole organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a contractile vacuole. A specialized vacuole that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010184", "l": "cytokinin transport", "d": ["The directed movement of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.245811769807808", "identifiers": [{"i": "GO:0001667", "l": "ameboidal-type cell migration", "d": ["Cell migration that is accomplished by extension and retraction of a pseudopodium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016270", "l": "O-glycan processing, core 4", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 4 O-glycan structure, GlcNAc-beta-(1->6)[GalNAc-beta-(1->3)]-GalNAc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035531", "l": "regulation of chemokine (C-C motif) ligand 6 production", "d": ["Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001208", "l": "negative regulation of transcription elongation by RNA polymerase I", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transcription elongation mediated by RNA polymerase I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904200", "l": "iodide transmembrane transport", "d": ["The process in which iodide is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030309", "l": "poly-N-acetyllactosamine metabolic process", "d": ["The chemical reactions and pathways involving poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048571", "l": "long-day photoperiodism", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that exceeds a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 hours minus the critical day length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905537", "l": "positive regulation of eukaryotic translation initiation factor 4F complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009169", "l": "purine ribonucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046627", "l": "negative regulation of insulin receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070368", "l": "positive regulation of hepatocyte differentiation", "d": ["Any process that activates or increases the rate or extent of hepatocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0014829", "l": "vascular associated smooth muscle contraction", "d": ["A process, occurring in the vascular tissue, whereby actin/myosin complex activity generates force through ATP hydrolysis resulting in a change in smooth muscle geometry. This process is always coupled to chemo-mechanical energy conversion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048146", "l": "positive regulation of fibroblast proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0098517", "l": "detection of low humidity", "d": ["The series of events in which low humidity is detected and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0003129", "l": "heart induction", "d": ["The close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030948", "l": "negative regulation of vascular endothelial growth factor receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120177", "l": "negative regulation of torso signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the torso signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902616", "l": "acyl carnitine transmembrane transport", "d": ["The process in which acyl carnitine is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001994", "l": "norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure", "d": ["A process that results in a decrease in the diameter of an artery during the norepinephrine-epinephrine response to decreased blood pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060332", "l": "positive regulation of response to type II interferon", "d": ["Any process that increases the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046383", "l": "dTDP-rhamnose metabolic process", "d": ["The chemical reactions and pathways involving dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006742", "l": "NADP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; catabolism may be of either the oxidized form, NADP, or the reduced form, NADPH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000234", "l": "positive regulation of rRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of rRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002726", "l": "positive regulation of T cell cytokine production", "d": ["Any process that activates or increases the frequency, rate, or extent of T cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061193", "l": "taste bud development", "d": ["The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990067", "l": "intrachromosomal DNA recombination", "d": ["The process of DNA recombination occurring within a single chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046224", "l": "bacteriocin metabolic process", "d": ["The chemical reactions and pathways involving bacteriocins, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010986", "l": "positive regulation of lipoprotein particle clearance", "d": ["Any process that increases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035029", "l": "dorsal closure, leading edge cell fate commitment", "d": ["The commitment of cells to leading edge cell fate during dorsal closure. Leading edge cells are the dorsal-most cells of the migrating epidermis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0046283", "l": "anthocyanin-containing compound metabolic process", "d": ["The chemical reactions and pathways involving anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins that occur in plants. They are responsible from most of the scarlet, purple, mauve and blue coloring in higher plants, especially of flowers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048576", "l": "positive regulation of short-day photoperiodism, flowering", "d": ["Any process that activates, maintains or increases short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051468", "l": "detection of glucocorticoid hormone stimulus", "d": ["The series of events by which a glucocorticoid hormone stimulus is received by a cell and converted into a molecular signal. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0101023", "l": "vascular endothelial cell proliferation", "d": ["The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035138", "l": "pectoral fin morphogenesis", "d": ["The process in which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048358", "l": "mucilage pectin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the pectin component of mucilage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000465", "l": "exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 5'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0090266", "l": "regulation of mitotic cell cycle spindle assembly checkpoint", "d": ["Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1903513", "l": "endoplasmic reticulum to cytosol transport", "d": ["The directed movement of substances from endoplasmic reticulum to cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990488", "l": "anaerobic cellulose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, in absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903210", "l": "podocyte apoptotic process", "d": ["Any apoptotic process in a glomerular visceral epithelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006477", "l": "protein sulfation", "d": ["The addition of a sulfate group as an ester to a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019456", "l": "L-cysteine catabolic process via cystine, using cysteine transaminase", "d": ["The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cysteine transaminase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009660", "l": "amyloplast organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an amyloplast. An amyloplast is a plastid whose main function is to synthesize and store starch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0039635", "l": "suppression by virus of host peptidoglycan biosynthetic process", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141013", "l": "purine nucleotide import into lysosome", "d": ["The directed import of purine nucleotide from the cytosol, across the lysosomal membrane, into the lysosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070616", "l": "regulation of thiamine diphosphate biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0006554", "l": "lysine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900924", "l": "negative regulation of glycine import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glycine import into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:0010981", "l": "regulation of cell wall macromolecule metabolic process", "d": ["Any process that modulates the rate, frequency or extent of cell wall macromolecule metabolism. Cell wall macromolecule metabolic processes are the chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043165", "l": "Gram-negative-bacterium-type cell outer membrane assembly", "d": ["The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0005513", "l": "detection of calcium ion", "d": ["The series of events in which a calcium ion stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016256", "l": "N-glycan processing to lysosome", "d": ["The modification of high-mannose N-glycans by UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase and the subsequent removal of the N-acetylglucosamine residues yielding mannose-6-P that occurs in the ER-Golgi apparatus to N-glycans destined for the lysosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036471", "l": "cellular response to glyoxal", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyoxal stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015828", "l": "tyrosine transport", "d": ["The directed movement of tyrosine, 2-amino-3-(4-hydroxyphenyl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0046349", "l": "amino sugar biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing an amino group in place of a hydroxyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0000054", "l": "ribosomal subunit export from nucleus", "d": ["The directed movement of a ribosomal subunit from the nucleus into the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0043652", "l": "engulfment of apoptotic cell", "d": ["The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039689", "l": "negative stranded viral RNA replication", "d": ["A viral genome replication process where the template genome is negative stranded, single stranded RNA ((-)ssRNA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018306", "l": "iron incorporation into iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0072014", "l": "proximal tubule development", "d": ["The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.783030043623796", "identifiers": [{"i": "GO:0030218", "l": "erythrocyte differentiation", "d": ["The process in which a myeloid precursor cell acquires specializes features of an erythrocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110098", "l": "positive regulation of calcium import into the mitochondrion", "d": ["Any process that activates or increases the frequency, rate or extent of calcium import into the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903299", "l": "regulation of hexokinase activity", "d": ["Any process that modulates the frequency, rate or extent of hexokinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061792", "l": "secretory granule maturation", "d": ["Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodeling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904124", "l": "microglial cell migration", "d": ["The orderly movement of a microglial cell from one site to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061129", "l": "negative regulation of positive chemotaxis to cAMP by DIF-2", "d": ["Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036364", "l": "transforming growth factor beta1 activation", "d": ["The release of transforming growth factor beta1 (TGF-beta1) from its latent state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.250759876326711", "identifiers": [{"i": "GO:0010324", "l": "membrane invagination", "d": ["The infolding of a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:2001057", "l": "reactive nitrogen species metabolic process", "d": ["The chemical reactions and pathways involving a reactive nitrogen species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0003144", "l": "embryonic heart tube formation", "d": ["The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0098917", "l": "retrograde trans-synaptic signaling", "d": ["Cell-cell signaling from post to pre-synapse, across the synaptic cleft."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002457", "l": "T cell antigen processing and presentation", "d": ["The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902770", "l": "negative regulation of choline O-acetyltransferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of choline O-acetyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0110058", "l": "positive regulation of blood vessel endothelial cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.783030043623796", "identifiers": [{"i": "GO:0055001", "l": "muscle cell development", "d": ["The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021726", "l": "lateral reticular nucleus development", "d": ["The process whose specific outcome is the progression of the lateral reticular nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.27567501185726", "identifiers": [{"i": "GO:0010557", "l": "positive regulation of macromolecule biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.871876592857262", "identifiers": [{"i": "GO:0030421", "l": "defecation", "d": ["The expulsion of feces from the rectum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031287", "l": "positive regulation of sorocarp stalk cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035309", "l": "wing and notum subfield formation", "d": ["The regionalization process that subdivides the wing imaginal disc into the wing and notum (body wall) subfields, thus determining whether cells ultimately differentiate wing or notum-specific structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032746", "l": "positive regulation of interleukin-22 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-22 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901834", "l": "regulation of deadenylation-independent decapping of nuclear-transcribed mRNA", "d": ["Any process that modulates the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042436", "l": "indole-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048767", "l": "root hair elongation", "d": ["The process in which the root hair grows longer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0001649", "l": "osteoblast differentiation", "d": ["The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060944", "l": "neural crest-derived cardiac fibroblast cell fate commitment", "d": ["The commitment of neural crest cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048614", "l": "post-embryonic ectodermal digestive tract morphogenesis", "d": ["The process, occurring during the post-embryonic phase, by which the anatomical structures of the ectodermal gut are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010770", "l": "positive regulation of cell morphogenesis involved in differentiation", "d": ["Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018890", "l": "cyanamide metabolic process", "d": ["The chemical reactions and pathways involving cyanamide, NCNH2, a cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The citrated calcium salt is used in the treatment of alcoholism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045747", "l": "positive regulation of Notch signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0070071", "l": "proton-transporting two-sector ATPase complex assembly", "d": ["The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901511", "l": "(-)-microperfuranone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (-)-microperfuranone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046081", "l": "dUTP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dUTP, deoxyuridine (5'-)triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904982", "l": "sucrose transmembrane transport", "d": ["The process in which sucrose is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904785", "l": "regulation of asymmetric protein localization involved in cell fate determination", "d": ["Any process that modulates the frequency, rate or extent of asymmetric protein localization involved in cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0046135", "l": "pyrimidine nucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046585", "l": "enniatin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140898", "l": "CENP-A eviction from euchromatin", "d": ["A chromatin remodeling process in which CENP-A is removed from euchromatin regions to prevent neocentromere formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.432445482536949", "identifiers": [{"i": "GO:0050866", "l": "negative regulation of cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.897328916711686", "identifiers": [{"i": "GO:0033365", "l": "protein localization to organelle", "d": ["A process in which a protein is transported to, or maintained in, a location within an organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0039005", "l": "specification of pronephric tubule identity", "d": ["The process in which the tubules arranged along the proximal/distal axis of the pronephric nephron acquire their identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902816", "l": "regulation of protein localization to microtubule", "d": ["Any process that modulates the frequency, rate or extent of protein localization to microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0003386", "l": "amphid sensory organ development", "d": ["The progression of the amphid sensory organ over time, from its formation to the mature structure. Amphid sensory organs are the sensory organs of nematodes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.646478505545467", "identifiers": [{"i": "GO:0034097", "l": "response to cytokine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002388", "l": "immune response in Peyer's patch", "d": ["Immune response taking place in the Peyer's patch, nodular lymphoid structures on the serosal surface of the small intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0043304", "l": "regulation of mast cell degranulation", "d": ["Any process that modulates the frequency, rate, or extent of mast cell degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "48.713864895144894", "identifiers": [{"i": "GO:0060255", "l": "regulation of macromolecule metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903817", "l": "negative regulation of voltage-gated potassium channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990691", "l": "cis-Golgi-derived vesicle fusion with Golgi medial cisterna membrane", "d": ["The joining of the lipid bilayer membrane around a cis-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Vesicles are involved in anterograde transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030264", "l": "nuclear fragmentation involved in apoptotic nuclear change", "d": ["The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140991", "l": "piRNA-mediated gene silencing by mRNA destabilization", "d": ["A cytoplasmic post-transcriptional gene silencing pathway in which piRNAs direct the cleavage of target mRNAs. The target mRNA, often transcribed from a transposable element, is destabilized by the activity of a PIWI class endonuclease within the piRNA-induced silencing complex. This may also be accompanied by mRNA deadenylation and decapping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0044001", "l": "migration in host", "d": ["The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003191", "l": "coronary sinus valve formation", "d": ["The developmental process pertaining to the initial formation of the coronary sinus valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902569", "l": "negative regulation of activation of Janus kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of activation of JAK (Janus Activated Kinase) kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048632", "l": "negative regulation of skeletal muscle tissue growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1901080", "l": "regulation of relaxation of smooth muscle", "d": ["Any process that modulates the frequency, rate or extent of relaxation of smooth muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0072114", "l": "pronephros morphogenesis", "d": ["The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905221", "l": "positive regulation of platelet formation", "d": ["Any process that activates or increases the frequency, rate or extent of platelet formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000378", "l": "negative regulation of reactive oxygen species metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903846", "l": "positive regulation of cellular response to transforming growth factor beta stimulus", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to transforming growth factor beta stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:0042632", "l": "cholesterol homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048329", "l": "negative regulation of axial mesodermal cell fate specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002851", "l": "positive regulation of peripheral T cell tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of peripheral T cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035360", "l": "positive regulation of peroxisome proliferator activated receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904495", "l": "negative regulation of substance P secretion, neurotransmission", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion, neurotransmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905857", "l": "positive regulation of pentose-phosphate shunt", "d": ["Any process that activates or increases the frequency, rate or extent of pentose-phosphate shunt."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904260", "l": "negative regulation of basement membrane assembly involved in embryonic body morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007445", "l": "determination of imaginal disc primordium", "d": ["Allocation of embryonic cells to the imaginal disc founder populations, groups of cells that are committed to contribute to the formation of an imaginal disc compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000633", "l": "positive regulation of pre-miRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of pre-microRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006050", "l": "mannosamine metabolic process", "d": ["The chemical reactions and pathways involving mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903946", "l": "negative regulation of ventricular cardiac muscle cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ventricular cardiac muscle cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036262", "l": "granulysin production", "d": ["The appearance of granulysin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903043", "l": "positive regulation of chondrocyte hypertrophy", "d": ["Any process that activates or increases the frequency, rate or extent of chondrocyte hypertrophy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042774", "l": "plasma membrane ATP synthesis coupled electron transport", "d": ["The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP in the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.990900157612501", "identifiers": [{"i": "GO:0034763", "l": "negative regulation of transmembrane transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0003299", "l": "muscle hypertrophy in response to stress", "d": ["The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells as a result of a disturbance in organismal or cellular homeostasis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.443919496911477", "identifiers": [{"i": "GO:0002456", "l": "T cell mediated immunity", "d": ["Any process involved in the carrying out of an immune response by a T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.9148261867131", "identifiers": [{"i": "GO:0006505", "l": "GPI anchor metabolic process", "d": ["The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097398", "l": "cellular response to interleukin-17", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902760", "l": "Mo(VI)-molybdopterin cytosine dinucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of Mo(VI)-molybdopterin cytosine dinucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001311", "l": "lysobisphosphatidic acid metabolic process", "d": ["The chemical reactions and pathways involving a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0006470", "l": "protein dephosphorylation", "d": ["The process of removing one or more phosphoric residues from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060676", "l": "ureteric bud formation", "d": ["The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034334", "l": "adherens junction maintenance", "d": ["The maintenance of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0010416", "l": "arabinoxylan-containing compound metabolic process", "d": ["The chemical reactions and pathways involving an arabinoxylan, a polymer containing a beta-1,4-linked D-xylose backbone decorated with arabinose side units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060195", "l": "negative regulation of antisense RNA transcription", "d": ["Any process that decreases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042870", "l": "D-glucarate transmembrane transport", "d": ["The process in which D-glucarate, the D-enantiomer of glucarate, is transported across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900684", "l": "negative regulation of fumonisin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fumonisin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000674", "l": "regulation of type B pancreatic cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001970", "l": "positive regulation of activation of membrane attack complex", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.248384282929521", "identifiers": [{"i": "GO:1901652", "l": "response to peptide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904129", "l": "positive regulation of convergent extension involved in somitogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of convergent extension involved in somitogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043952", "l": "protein transport by the Sec complex", "d": ["The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.326077654855553", "identifiers": [{"i": "GO:0046717", "l": "acid secretion", "d": ["The controlled release of acid by a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903955", "l": "positive regulation of protein targeting to mitochondrion", "d": ["Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900743", "l": "positive regulation of filamentous growth of a population of unicellular organisms in response to pH", "d": ["Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072049", "l": "comma-shaped body morphogenesis", "d": ["The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046103", "l": "inosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002125", "l": "maternal aggressive behavior", "d": ["Aggressive behavior of a female to protect her offspring from a threat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036359", "l": "renal potassium excretion", "d": ["The elimination of potassium ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032883", "l": "regulation of chitin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009852", "l": "auxin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of auxins, a group of plant hormones that regulate aspects of plant growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.362525179576039", "identifiers": [{"i": "GO:0000723", "l": "telomere maintenance", "d": ["Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010152", "l": "pollen maturation", "d": ["The final stages of microgametogenesis after the trinucleate stage has been reached resulting in viable pollen grains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034275", "l": "kynurenic acid metabolic process", "d": ["The chemical reactions and pathways involving kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007470", "l": "prothoracic disc morphogenesis", "d": ["The process in which the anatomical structures derived from the prothoracic disc are generated and organized. This includes the transformation of a prothoracic imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult humerous and anterior spiracle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043619", "l": "regulation of transcription from RNA polymerase II promoter in response to oxidative stress", "d": ["Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031535", "l": "plus-end directed microtubule sliding", "d": ["The movement of one microtubule along another microtubule, where the motion is directed towards the plus ends of the microtubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045070", "l": "positive regulation of viral genome replication", "d": ["Any process that activates or increases the frequency, rate or extent of viral genome replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072515", "l": "trehalose transport in response to desiccation", "d": ["The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of a desiccation stimulus. A desiccation stimulus signals extreme dryness resulting from the prolonged deprivation of water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0050731", "l": "positive regulation of peptidyl-tyrosine phosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048539", "l": "bone marrow development", "d": ["The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903139", "l": "positive regulation of cell wall integrity MAPK cascade", "d": ["Any process that activates or increases the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.455144077809102", "identifiers": [{"i": "GO:0009582", "l": "detection of abiotic stimulus", "d": ["The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901934", "l": "bicyclogermacrene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of bicyclogermacrene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046326", "l": "positive regulation of glucose import", "d": ["Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0035601", "l": "protein deacylation", "d": ["The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000436", "l": "positive regulation of protein neddylation", "d": ["Any process that activates or increases the frequency, rate or extent of protein neddylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905716", "l": "negative regulation of cornification", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cornification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010085", "l": "polarity specification of proximal/distal axis", "d": ["Any process resulting in the establishment of polarity along the proximal/distal axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030420", "l": "establishment of competence for transformation", "d": ["The process in which a naturally transformable bacterium acquires the ability to take up exogenous DNA. This term should be applied only to naturally transformable bacteria, and should not be used in the context of artificially induced bacterial transformation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0071071", "l": "regulation of phospholipid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905244", "l": "regulation of modification of synaptic structure", "d": ["Any process that modulates the frequency, rate or extent of modification of synaptic structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0062111", "l": "zinc ion import into organelle", "d": ["The directed import of zinc(2+) from the cytosol, across an organelle membrane, into the organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070797", "l": "negative regulation of cleistothecium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0099112", "l": "microtubule polymerization based protein transport", "d": ["The transport of a protein driven by polymerization of a microtubule to which it is attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901517", "l": "aspyridone A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aspyridone A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062000", "l": "positive regulation of cardiac endothelial to mesenchymal transition", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac endothelial to mesenchymal trnasition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042159", "l": "lipoprotein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905284", "l": "positive regulation of epidermal growth factor receptor signaling pathway involved in heart process", "d": ["Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904626", "l": "positive regulation of glycine secretion, neurotransmission", "d": ["Any process that activates or increases the frequency, rate or extent of glycine secretion, neurotransmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002267", "l": "follicular dendritic cell activation involved in immune response", "d": ["A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010344", "l": "seed oilbody biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a seed oilbody. Seed oilbodies are simple organelles comprising a matrix of triglyceride surrounded by a phospholipid monolayer embedded and covered with unique proteins called oleosins. Seed oilbodies supply the energy requirements for the growth of the seedling after germination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900954", "l": "negative regulation of 18-methylnonadec-1-ene metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036509", "l": "trimming of terminal mannose on B branch", "d": ["The removal of an alpha-1,2-linked mannose from the B-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006193", "l": "ITP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ITP, inosine (5'-)triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036298", "l": "recombinational interstrand cross-link repair", "d": ["Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous DNA region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075512", "l": "clathrin-dependent endocytosis of virus by host cell", "d": ["Any clathrin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicle containing the virus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009819", "l": "drought recovery", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of prolonged deprivation of water that restores that organism to a normal (non-stressed) condition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010143", "l": "cutin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cutin, a waxy substance, which combined with cellulose forms a substance nearly impervious to water and constituting the cuticle in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110044", "l": "regulation of cell cycle switching, mitotic to meiotic cell cycle", "d": ["Any process that modulates the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061445", "l": "endocardial cushion cell fate commitment", "d": ["The commitment of a cell to an endocardial cushion cell fate and its capacity to differentiate into an endocardial cushion cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0097468", "l": "programmed cell death in response to reactive oxygen species", "d": ["Cell death resulting from activation of endogenous cellular processes and occurring as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0002260", "l": "lymphocyte homeostasis", "d": ["The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018914", "l": "chlorobenzene metabolic process", "d": ["The chemical reactions and pathways involving chlorobenzene, a derivative of benzene with a chlorine atoms attached to the ring. It is a colorless liquid that is manufactured for use as a solvent. It quickly evaporates in the air and is degraded by hydroxyl radicals that are produced photochemically. The gas acts as a source of ClOx, which helps in the breakdown of stratospheric ozone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098670", "l": "entry receptor-mediated virion attachment to host cell", "d": ["The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that mediates/triggers viral entry by endocytosis/pinocytosis or by inducing fusion/penetration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900026", "l": "positive regulation of substrate adhesion-dependent cell spreading", "d": ["Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090170", "l": "regulation of Golgi inheritance", "d": ["Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.759446066112609", "identifiers": [{"i": "GO:0055088", "l": "lipid homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of lipid within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090539", "l": "peptide pheromone export by transmembrane transport", "d": ["The directed movement of a peptide pheromone across a membrane and out of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002458", "l": "peripheral T cell tolerance induction", "d": ["Tolerance induction of T cells in the periphery, in this case, any location in the body other than the thymus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060178", "l": "regulation of exocyst localization", "d": ["Any process that modulates the localization of exocysts. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.366262559334615", "identifiers": [{"i": "GO:0046467", "l": "membrane lipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000252", "l": "negative regulation of feeding behavior", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901790", "l": "3-(2,3-dihydroxyphenyl)propanoate metabolic process", "d": ["The chemical reactions and pathways involving 3-(2,3-dihydroxyphenyl)propanoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090325", "l": "regulation of locomotion involved in locomotory behavior", "d": ["Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046329", "l": "negative regulation of JNK cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903177", "l": "negative regulation of tyrosine 3-monooxygenase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tyrosine 3-monooxygenase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048462", "l": "carpel formation", "d": ["The process that gives rise to the carpel. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110089", "l": "regulation of hippocampal neuron apoptotic process", "d": ["Any process that modulates the occurrence or rate of cell death by apoptotic process in hippocampal neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010062", "l": "negative regulation of trichoblast fate specification", "d": ["Any process that suppresses trichoblast fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0050931", "l": "pigment cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.036345600355318", "identifiers": [{"i": "GO:0042181", "l": "ketone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0016322", "l": "neuron remodeling", "d": ["The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036061", "l": "muscle cell chemotaxis toward tendon cell", "d": ["The directed movement of a muscle cell towards a tendon cell in response to an external stimulus. Tendon cells, for example, produce positive guidance cues that attract muscle cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061446", "l": "endocardial cushion cell fate determination", "d": ["The process involved in endocardial cushion cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042494", "l": "detection of bacterial lipoprotein", "d": ["The series of events in which a bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Bacterial lipoproteins are lipoproteins characterized by the presence of conserved sequence motifs called pathogen-associated molecular patterns (PAMPs)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0033048", "l": "negative regulation of mitotic sister chromatid segregation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060345", "l": "spleen trabecula formation", "d": ["The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002288", "l": "NK T cell activation involved in immune response", "d": ["The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905446", "l": "regulation of mitochondrial ATP synthesis coupled electron transport", "d": ["Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019603", "l": "toluene oxidation via 4-hydroxytoluene", "d": ["The degradation of toluene to form p-hydroxybenzoate; the first step in the pathway is the oxidation of toluene to form 4-hydroxytoluene (4-cresol)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002631", "l": "regulation of granuloma formation", "d": ["Any process that modulates the frequency, rate, or extent of granuloma formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0007432", "l": "salivary gland boundary specification", "d": ["Determination of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.70771016742691", "identifiers": [{"i": "GO:0043604", "l": "amide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060404", "l": "axonemal microtubule depolymerization", "d": ["The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900459", "l": "positive regulation of brassinosteroid mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of brassinosteroid mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010937", "l": "regulation of cytoplasmic microtubule depolymerization", "d": ["Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090254", "l": "cell elongation involved in imaginal disc-derived wing morphogenesis", "d": ["The process in which a cell elongates and contributes to imaginal disc-derived wing morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035456", "l": "response to interferon-beta", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "43.432318458018344", "identifiers": [{"i": "GO:0051641", "l": "cellular localization", "d": ["A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000861", "l": "regulation of estrogen secretion", "d": ["Any process that modulates the frequency, rate or extent of estrogen secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039592", "l": "suppression by virus of G2/M transition of host mitotic cell cycle", "d": ["Any viral process that decreases the rate or extent of progression from G2 phase to M phase of the host mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044418", "l": "translocation of DNA into host", "d": ["The directed movement of DNA from an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043980", "l": "histone H2B-K12 acetylation", "d": ["The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 12 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060217", "l": "hemangioblast cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the characteristics of a mature hemangioblast. Hemangioblasts are the proposed common precursor of blood and endothelial lineages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0014856", "l": "skeletal muscle cell proliferation", "d": ["The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019434", "l": "sophorosyloxydocosanoate metabolic process", "d": ["The chemical reactions and pathways involving sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate, an aromatic hydrocarbon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140883", "l": "induction by virus of host reticulophagy", "d": ["Any process in which a virus activates or increases the frequency, rate or extent of reticulophagy in the host."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:1903401", "l": "L-lysine transmembrane transport", "d": ["The directed movement of L-lysine across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:2001053", "l": "regulation of mesenchymal cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.510429476229447", "identifiers": [{"i": "GO:0032943", "l": "mononuclear cell proliferation", "d": ["The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003319", "l": "cardioblast migration to the midline involved in heart rudiment formation", "d": ["The orderly movement of a cardioblast toward the midline that contributes to the initial appearance of the heart rudiment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900965", "l": "regulation of methanophenazine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of methanophenazine metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140384", "l": "metacyclogenesis", "d": ["The morphological, biochemical and genetic changes that induce the differentiation of non-pathogenic parasites into pathogenic metacyclic parasites in the Trypanosomatidae species. The pathogenic parasites are known as metacyclic trypomastigotes in Trypanosoma and metacyclic promastigotes in Leishmania."]}]}
{"type": "biolink:BiologicalProcess", "ic": "31.866832381063869", "identifiers": [{"i": "GO:0051301", "l": "cell division", "d": ["The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905737", "l": "positive regulation of L-proline import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of L-proline import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0034651", "l": "cortisol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0060612", "l": "adipose tissue development", "d": ["The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900249", "l": "positive regulation of cytoplasmic translational elongation", "d": ["Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031147", "l": "1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process", "d": ["The chemical reactions and pathways involving 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900197", "l": "negative regulation of penicillin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of penicillin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021560", "l": "abducens nerve development", "d": ["The process whose specific outcome is the progression of the abducens nerve over time, from its formation to the mature structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034608", "l": "vulval location", "d": ["Location, by the male, of his partner's vulva when backing along the ventral side of the hermaphrodite during mating. The male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052130", "l": "negative aerotaxis", "d": ["The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009291", "l": "unidirectional conjugation", "d": ["The process of unidirectional (polarized) transfer of genetic information involving direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells. Some or all of the chromosome(s) of the donor cell is transferred into the recipient cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048923", "l": "posterior lateral line neuromast hair cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018386", "l": "N-terminal peptidyl-cysteine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-cysteine", "d": ["The condensation of pyruvate through the 2-oxo group with the N-terminal cysteine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0019985", "l": "translesion synthesis", "d": ["The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014030", "l": "mesenchymal cell fate commitment", "d": ["The process in which a cell becomes committed to become a mesenchymal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901960", "l": "isobutanol metabolic process", "d": ["The chemical reactions and pathways involving isobutanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032876", "l": "negative regulation of DNA endoreduplication", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0035112", "l": "genitalia morphogenesis", "d": ["The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000155", "l": "positive regulation of cilium-dependent cell motility", "d": ["Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009205", "l": "purine ribonucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0002313", "l": "mature B cell differentiation involved in immune response", "d": ["The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0006940", "l": "regulation of smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019592", "l": "mannitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0003161", "l": "cardiac conduction system development", "d": ["The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048163", "l": "scattered antral spaces stage", "d": ["The stage in oogenesis when antral spaces begin to form in the follicle cells. Mitochondria form centers for yolk concentration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905192", "l": "regulation of chloroplast fission", "d": ["Any process that modulates the frequency, rate or extent of chloroplast fission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072537", "l": "fibroblast activation", "d": ["A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097280", "l": "histamine secretion mediated by immunoglobulin", "d": ["Histamine release triggered by the binding of an antigen to an immunoglobulin bound to the cell surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0060464", "l": "lung lobe formation", "d": ["The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2000198", "l": "negative regulation of ribonucleoprotein complex localization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0071900", "l": "regulation of protein serine/threonine kinase activity", "d": ["Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048173", "l": "positive regulation of short-term neuronal synaptic plasticity", "d": ["A process that increases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006679", "l": "glucosylceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0006282", "l": "regulation of DNA repair", "d": ["Any process that modulates the frequency, rate or extent of DNA repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042906", "l": "xanthine transport", "d": ["The directed movement of xanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0060935", "l": "cardiac fibroblast cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045607", "l": "regulation of inner ear auditory receptor cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of auditory hair cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0045472", "l": "response to ether", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070409", "l": "carbamoyl phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905417", "l": "negative regulation of amoeboid sperm motility", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amoeboid sperm motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901067", "l": "ferulate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ferulate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902824", "l": "positive regulation of late endosome to lysosome transport", "d": ["Any process that activates or increases the frequency, rate or extent of late endosome to lysosome transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140207", "l": "tripeptide import across plasma membrane", "d": ["The directed movement of a tripeptide from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0031548", "l": "regulation of brain-derived neurotrophic factor receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0001556", "l": "oocyte maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106116", "l": "positive regulation of mitotic cohesin dsDNA (leading strand) loading", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070237", "l": "positive regulation of activation-induced cell death of T cells", "d": ["Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046411", "l": "2-keto-3-deoxygluconate transmembrane transport", "d": ["The process in which 2-keto-3-deoxygluconate is transported across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061670", "l": "evoked neurotransmitter secretion", "d": ["Neurotransmitter secretion that occurs in the presence of the action of a secretagogue or a presynaptic action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.391164428010192", "identifiers": [{"i": "GO:0008213", "l": "protein alkylation", "d": ["The addition of an alkyl group to a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001113", "l": "negative regulation of cellular response to hepatocyte growth factor stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.958453806446542", "identifiers": [{"i": "GO:0160043", "l": "catecholamine secretion, neurotransmission", "d": ["The regulated release of catecholamine by a cell in which the catecholamine acts as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060574", "l": "intestinal epithelial cell maturation", "d": ["The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0019627", "l": "urea metabolic process", "d": ["The chemical reactions and pathways involving urea, the water soluble compound O=C-(NH2)2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0061227", "l": "pattern specification involved in mesonephros development", "d": ["Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070142", "l": "synaptic vesicle budding", "d": ["Evagination of a membrane to form a synaptic vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000644", "l": "regulation of receptor catabolic process", "d": ["Any process that modulates the frequency, rate or extent of receptor catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901097", "l": "negative regulation of autophagosome maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0071331", "l": "cellular response to hexose stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097719", "l": "neural tissue regeneration", "d": ["The regrowth of neural tissue following its loss or destruction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010208", "l": "pollen wall assembly", "d": ["The formation of reticulate pollen wall pattern consisting of two layers, exine and intine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0019362", "l": "pyridine nucleotide metabolic process", "d": ["The chemical reactions and pathways involving a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904984", "l": "regulation of quinolinate biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of quinolinate biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097045", "l": "phosphatidylserine exposure on blood platelet", "d": ["A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of activated blood platelets, and triggers the clotting system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "50.779817989337566", "identifiers": [{"i": "GO:0070727", "l": "cellular macromolecule localization", "d": ["Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046244", "l": "salicylic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902024", "l": "L-histidine transport", "d": ["The directed movement of a L-histidine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090326", "l": "positive regulation of locomotion involved in locomotory behavior", "d": ["Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021890", "l": "olfactory bulb interneuron fate commitment", "d": ["The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into an interneuron residing in the olfactory bulb."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0019884", "l": "antigen processing and presentation of exogenous antigen", "d": ["The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071983", "l": "exit from reproductive diapause", "d": ["The dormancy process that results in exit from reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002006", "l": "vasoconstriction by vasopressin involved in systemic arterial blood pressure control", "d": ["The decrease in blood vessel diameter as a result of the release of vasopressin into the blood stream."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014717", "l": "regulation of satellite cell activation involved in skeletal muscle regeneration", "d": ["Any process that modulates the frequency, rate or extent of satellite cell activation. The satellite cell activation is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0034314", "l": "Arp2/3 complex-mediated actin nucleation", "d": ["The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0002070", "l": "epithelial cell maturation", "d": ["The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006391", "l": "transcription initiation at mitochondrial promoter", "d": ["A transcription initiation process that takes place at a promoter on the mitochondrial chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0002254", "l": "kinin cascade", "d": ["A series of reactions that takes place outside the cell that occur as a result of by-products of tissue damage, including collagen, cartilage, and basement membrane. The ultimate product of the kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.116918913335823", "identifiers": [{"i": "GO:1901503", "l": "ether biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ether."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033069", "l": "ansamycin metabolic process", "d": ["The chemical reactions and pathways involving ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061681", "l": "Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate", "d": ["The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde-3-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:1900274", "l": "regulation of phospholipase C activity", "d": ["Any process that modulates the frequency, rate or extent of phospholipase C activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905629", "l": "positive regulation of serotonin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000740", "l": "nuclear membrane fusion", "d": ["The joining of 2 or more lipid bilayer membranes that surround the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140669", "l": "negative regulation of oxytocin production", "d": ["Any process that stops, prevents, or reduces the rate of production of oxytocin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0045136", "l": "development of secondary sexual characteristics", "d": ["The process whose specific outcome is the progression of the secondary sexual characteristics over time, from their formation to the mature structures. In humans, these include growth of axillary, chest, and pubic hair, voice changes, testicular/penile enlargement, breast development and menstrual periods. Development occurs in response to sex hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021649", "l": "vestibulocochlear nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the vestibulocochlear nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039640", "l": "viral release via suppression of host peptidoglycan biosynthetic process", "d": ["The dissemination of mature viral particles from a host cell, caused by a virus stopping, preventing, or reducing peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060221", "l": "retinal rod cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140208", "l": "apoptotic process in response to mitochondrial fragmentation", "d": ["Any apoptotic process that occurs as a result of mitochondrial fragmentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048104", "l": "establishment of body hair or bristle planar orientation", "d": ["Orientation of hairs or sensory bristles that cover the body surface of an adult, such that they all point in a uniform direction along the plane of the epithelium from which they project."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:2000628", "l": "regulation of miRNA metabolic process", "d": ["Any process that modulates the frequency, rate or extent of miRNA metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010272", "l": "response to silver ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006667", "l": "sphinganine metabolic process", "d": ["The chemical reactions and pathways involving sphinganine, D-erythro-2-amino-1,3-octadecanediol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000486", "l": "negative regulation of glutamine transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glutamine transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "36.465189681502288", "identifiers": [{"i": "GO:0007399", "l": "nervous system development", "d": ["The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0042559", "l": "pteridine-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098702", "l": "adenine import across plasma membrane", "d": ["The directed movement of adenine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:1902102", "l": "regulation of metaphase/anaphase transition of meiotic cell cycle", "d": ["Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072679", "l": "thymocyte migration", "d": ["The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905767", "l": "regulation of double-stranded telomeric DNA binding", "d": ["Any process that modulates the frequency, rate or extent of double-stranded telomeric DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990775", "l": "endothelin production", "d": ["The appearance of a endothelin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:0052547", "l": "regulation of peptidase activity", "d": ["Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035317", "l": "imaginal disc-derived wing hair organization", "d": ["A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0052148", "l": "modulation by symbiont of host catalytic activity", "d": ["The process in which an organism effects a change in host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009837", "l": "fruit ripening, non-climacteric", "d": ["A fruit ripening process that does not involve a respiratory burst."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902777", "l": "6-sulfoquinovose(1-) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902313", "l": "positive regulation of copper ion transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of copper ion transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904565", "l": "response to 1-oleoyl-sn-glycerol 3-phosphate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0002777", "l": "antimicrobial peptide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an antimicrobial peptide. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090362", "l": "positive regulation of platelet-derived growth factor production", "d": ["Any process that increases the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.370574996118883", "identifiers": [{"i": "GO:0045786", "l": "negative regulation of cell cycle", "d": ["Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0002244", "l": "hematopoietic progenitor cell differentiation", "d": ["The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0062033", "l": "positive regulation of mitotic sister chromatid segregation", "d": ["Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036341", "l": "chitin-based cuticle sclerotization by protein cross-linking", "d": ["The process of hardening of a chitin-based cuticle by protein cross-linking, and the incorporation of phenolic precursors. This mechanism of cuticle hardening occurs in insects and is usually accompanied by darkening of the cuticle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018302", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090640", "l": "phosphatidylcholine biosynthesis from sn-glycero-3-phosphocholine", "d": ["The phosphatidylcholine biosynthetic process that involves the two-step acylation of sn-glycero-3-phosphocholine to a phosphatidylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071652", "l": "regulation of chemokine (C-C motif) ligand 1 production", "d": ["Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0017011", "l": "protein-phycoerythrobilin linkage", "d": ["The linkage of the chromophore phycoerythrobilin to phycoerythrins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018147", "l": "molybdenum incorporation via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide)", "d": ["The incorporation of molybdenum into a protein via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0045734", "l": "regulation of acetate catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900814", "l": "monodictyphenone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of monodictyphenone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090671", "l": "telomerase RNA localization to Cajal body", "d": ["A process in which telomerase RNA (TERC) is transported to, or maintained in, a Cajal body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106163", "l": "regulation of exonucleolytic catabolism of deadenylated mRNA", "d": ["Any process that modulates the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001051", "l": "positive regulation of tendon cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of tendon cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070753", "l": "interleukin-35 production", "d": ["The appearance of interleukin-35 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0018104", "l": "peptidoglycan-protein cross-linking", "d": ["The process of covalently linking peptidoglycan (murein) to proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045109", "l": "intermediate filament organization", "d": ["Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002331", "l": "pre-B cell allelic exclusion", "d": ["Expression of a single heavy chain allele during pre-B cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051334", "l": "meiosis I nuclear membrane reassembly", "d": ["The reformation of the nuclear membranes during meiosis I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:1900909", "l": "negative regulation of olefin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of olefin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905222", "l": "atrioventricular canal morphogenesis", "d": ["The developmental process by which an atrioventricular canal is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061305", "l": "maintenance of bipolar cell polarity regulating cell shape", "d": ["The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055121", "l": "response to high fluence blue light stimulus by blue high-fluence system", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a high fluence blue light stimulus by the blue high-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue high-fluence system responds to blue light at levels between 100 and 1000 micromols/m2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032651", "l": "regulation of interleukin-1 beta production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-1 beta production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021505", "l": "neural fold folding", "d": ["The process of folding the neuroepithelium around the medial hinge point to create the neural elevations, and around the lateral hinge points to produce convergence of the folds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080192", "l": "primary thickening", "d": ["Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from the activity of a primary thickening meristem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0089709", "l": "L-histidine transmembrane transport", "d": ["The directed movement of L-histidine across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0045875", "l": "negative regulation of sister chromatid cohesion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid cohesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0097164", "l": "ammonium ion metabolic process", "d": ["The chemical reactions and pathways involving the ammonium ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903527", "l": "positive regulation of membrane tubulation", "d": ["Any process that activates or increases the frequency, rate or extent of membrane tubulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003149", "l": "membranous septum morphogenesis", "d": ["The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904220", "l": "regulation of serine C-palmitoyltransferase activity", "d": ["Any process that modulates the frequency, rate or extent of serine C-palmitoyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072410", "l": "response to meiotic cell cycle checkpoint signaling", "d": ["A process that acts directly to delay or stop progression through the cell cycle in response to signals generated as a result of meiotic cell cycle checkpoint signaling; contributes to a meiotic cell cycle checkpoint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0021843", "l": "substrate-independent telencephalic tangential interneuron migration", "d": ["The directional movement of tangentially migrating interneurons that are not guided by attaching to extracellular substrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.523981342372721", "identifiers": [{"i": "GO:0009896", "l": "positive regulation of catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0098742", "l": "cell-cell adhesion via plasma-membrane adhesion molecules", "d": ["The attachment of one cell to another cell via adhesion molecules that are at least partially embedded in the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030505", "l": "inorganic diphosphate transport", "d": ["The directed movement of inorganic diphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900669", "l": "positive regulation of endocrocin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of endocrocin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900167", "l": "negative regulation of glial cell-derived neurotrophic factor production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044482", "l": "envenomation resulting in blood vessel extracellular matrix damage, causing hemorrhagic damage in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism which causes damage to the extracellular matrix of the blood vessels of the bitten organism, ultimately resulting in hemorrhage in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010381", "l": "peroxisome-chloroplast membrane tethering", "d": ["The attachment of a peroxisome to a chloroplast via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017184", "l": "peptidyl-diphthamide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of peptidyl-diphthamide, a modified histidine residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045973", "l": "positive regulation of juvenile hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of juvenile hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905337", "l": "positive regulation of aggrephagy", "d": ["Any process that activates or increases the frequency, rate or extent of aggrephagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042404", "l": "thyroid hormone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0019249", "l": "lactate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lactate, the anion of lactic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0140274", "l": "repair of kinetochore microtubule attachment defect", "d": ["The cell cycle process where kinetochore microtubule attachment defects are corrected."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0030149", "l": "sphingolipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042665", "l": "regulation of ectodermal cell fate specification", "d": ["Any process that mediates the specification of a cell into an ectoderm cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030634", "l": "carbon fixation by acetyl-CoA pathway", "d": ["A pathway of carbon dioxide fixation in which one molecule of acetyl-CoA is completely synthesized from two molecules of carbon dioxide (CO2)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060068", "l": "vagina development", "d": ["The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060003", "l": "copper ion export", "d": ["The directed movement of copper ions out of a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080088", "l": "spermidine hydroxycinnamate conjugate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of spermidine hydroxycinnamate conjugates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015965", "l": "diadenosine tetraphosphate metabolic process", "d": ["The chemical reactions and pathways involving diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021886", "l": "hypothalamus gonadotrophin-releasing hormone neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron located in the hypothalamus. These neurons release gonadotrophin-releasing hormone as a neural transmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022016", "l": "pallium glioblast division", "d": ["The division of a glioblast in the pallium. A glioblast is a dividing precursor cell that gives rise to glial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046330", "l": "positive regulation of JNK cascade", "d": ["Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060486", "l": "club cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.648013125186591", "identifiers": [{"i": "GO:0044249", "l": "cellular biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904717", "l": "regulation of AMPA glutamate receptor clustering", "d": ["Any process that modulates the frequency, rate or extent of AMPA glutamate receptor clustering."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905795", "l": "cellular response to puromycin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905496", "l": "regulation of triplex DNA binding", "d": ["Any process that modulates the frequency, rate or extent of triplex DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904479", "l": "negative regulation of intestinal absorption", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intestinal absorption."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015936", "l": "coenzyme A metabolic process", "d": ["The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040039", "l": "inductive cell migration", "d": ["Migration of a cell in a multicellular organism that, having changed its location, is required to induce normal properties in one or more cells at its new location. An example of this would be the distal tip cells of Caenorhabditis elegans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046471", "l": "phosphatidylglycerol metabolic process", "d": ["The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. They are important constituents of cell membranes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036386", "l": "bacterial nucleoid packaging", "d": ["A process in which chromosomal DNA and associated proteins organize into a compact, orderly bacterial nucleoid. Often resulting in DNA supercoiling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0120165", "l": "perithecium development", "d": ["The process whose specific outcome is the progression of a perithecium over time, from its formation to the mature structure. Peritheicum is a flask-shaped fruiting body of certain molds and ascomycetous fungi having a pore for the escape of spores. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007437", "l": "adult salivary gland morphogenesis", "d": ["The process in which the anatomical structures of the adult salivary gland are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060651", "l": "regulation of epithelial cell proliferation involved in mammary gland bud elongation", "d": ["Any process that modulates the frequency, rate or extent of mammary gland bud epithelial cell proliferation that results in the elongation of the bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0002098", "l": "tRNA wobble uridine modification", "d": ["The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0036005", "l": "response to macrophage colony-stimulating factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0048243", "l": "norepinephrine secretion", "d": ["The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0061228", "l": "mesonephric nephron morphogenesis", "d": ["The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903689", "l": "regulation of wound healing, spreading of epidermal cells", "d": ["Any process that modulates the frequency, rate or extent of wound healing, spreading of epidermal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006019", "l": "deoxyribose 5-phosphate phosphorylation", "d": ["The process of introducing a phosphate group into deoxyribose 5-phosphate to produce deoxyribose bisphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903222", "l": "quinolinic acid transmembrane transport", "d": ["The process in which quinolinic acid is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090561", "l": "nuclear migration during mitotic telophase", "d": ["The dynein-driven microtubule based nuclear migration, whereby daughter nuclei are positioned away from the cell division site prior to cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090037", "l": "positive regulation of protein kinase C signaling", "d": ["Any process that increases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006509", "l": "membrane protein ectodomain proteolysis", "d": ["The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042509", "l": "regulation of tyrosine phosphorylation of STAT protein", "d": ["Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901764", "l": "phosphinothricin metabolic process", "d": ["The chemical reactions and pathways involving phosphinothricin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031319", "l": "detection of cAMP", "d": ["The series of events in which a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus is received by a cell and converted into a molecular signal; cAMP is the nucleotide cyclic AMP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0001923", "l": "B-1 B cell differentiation", "d": ["The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0048686", "l": "regulation of sprouting of injured axon", "d": ["Any process that modulates the frequency, rate or extent of sprouting of an injured axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0035933", "l": "glucocorticoid secretion", "d": ["The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035026", "l": "leading edge cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features of leading edge cells, cells at the front of a migrating epithelial sheet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905200", "l": "gibberellic acid transmembrane transport", "d": ["The directed movement of gibberellic acid across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072685", "l": "Mre11 complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an Mre11 complex, a trimeric protein complex that possesses endonuclease activity and is involved in meiotic recombination, DNA repair and checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905111", "l": "positive regulation of pulmonary blood vessel remodeling", "d": ["Any process that activates or increases the frequency, rate or extent of pulmonary blood vessel remodeling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032256", "l": "establishment of dense core granule localization", "d": ["The directed movement of a dense core granule to a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098997", "l": "fusion of virus membrane with host outer membrane", "d": ["Fusion of a viral membrane with the host cell outer membrane during viral entry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098829", "l": "intestinal folate absorption", "d": ["Uptake of folic into the blood by absorption from the small intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075012", "l": "negative regulation of germ tube formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.871876592857262", "identifiers": [{"i": "GO:0050951", "l": "sensory perception of temperature stimulus", "d": ["The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901728", "l": "monensin A metabolic process", "d": ["The chemical reactions and pathways involving monensin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043313", "l": "regulation of neutrophil degranulation", "d": ["Any process that modulates the frequency, rate, or extent of neutrophil degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904754", "l": "positive regulation of vascular associated smooth muscle cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039554", "l": "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity", "d": ["Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of MDA-5 (also known as IFIH1). The cytoplasmic pattern recognition receptor MDA-5 detects dsRNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904649", "l": "regulation of fat cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of fat cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0000087", "l": "mitotic M phase", "d": ["A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046130", "l": "purine ribonucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043049", "l": "otic placode formation", "d": ["The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000964", "l": "mitochondrial RNA 5'-end processing", "d": ["Any process involved in forming the mature 5' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000352", "l": "trans assembly of SL-containing precatalytic spliceosome", "d": ["Assembly of a spliceosomal complex containing the SL RNA and the pre-mRNA to be joined, as well as all the spliceosomal snRNPs involved in trans leader splicing. Formation of the trans leader spliceosome brings together the quadruple SL/U4/U5/U6 snRNP and the complex of the U2 snRNP with the splice site of the pre-mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071854", "l": "cell wall macromolecule catabolic process involved in fungal-type cell wall disassembly", "d": ["The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the fungal-type cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007370", "l": "ventral furrow formation", "d": ["Formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0000966", "l": "RNA 5'-end processing", "d": ["Any process involved in forming the mature 5' end of an RNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900802", "l": "cspyrone B1 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cspyrone B1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.552344973348063", "identifiers": [{"i": "GO:0006066", "l": "alcohol metabolic process", "d": ["The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001551", "l": "ovarian follicle endowment", "d": ["Association of oocytes with supporting epithelial granulosa cells to form primordial follicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009138", "l": "pyrimidine nucleoside diphosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015862", "l": "uridine transport", "d": ["The directed movement of uridine, uracil riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0042987", "l": "amyloid precursor protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:1905809", "l": "negative regulation of synapse organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901963", "l": "regulation of cell proliferation involved in outflow tract morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.282738951573606", "identifiers": [{"i": "GO:0060216", "l": "definitive hemopoiesis", "d": ["A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048564", "l": "photosystem I assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a photosystem I complex on the thylakoid membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0002658", "l": "regulation of peripheral tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of peripheral tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090171", "l": "chondrocyte morphogenesis", "d": ["The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0070571", "l": "negative regulation of neuron projection regeneration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0098581", "l": "detection of external biotic stimulus", "d": ["The series of events in which an external biotic stimulus is detected and converted into a molecular signal. An external biotic stimulus is defined as one caused or produced by a living organism other than the one being stimulated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072387", "l": "flavin adenine dinucleotide metabolic process", "d": ["The chemical reactions and pathways involving flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0014003", "l": "oligodendrocyte development", "d": ["The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.427648931207088", "identifiers": [{"i": "GO:0048666", "l": "neuron development", "d": ["The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0001935", "l": "endothelial cell proliferation", "d": ["The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0097502", "l": "mannosylation", "d": ["The covalent attachment of a mannose residue to a substrate molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043380", "l": "regulation of memory T cell differentiation", "d": ["Any process that modulates the frequency, rate, or extent of memory T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110039", "l": "positive regulation of nematode male tail tip morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of nematode male tail tip morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021758", "l": "putamen development", "d": ["The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140966", "l": "piRNA-directed heterochromatin formation", "d": ["The formation of heterochromatin into a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process mediated by a small interfering piRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048003", "l": "antigen processing and presentation of lipid antigen via MHC class Ib", "d": ["The process in which an antigen-presenting cell expresses lipid antigen in association with an MHC class Ib protein complex on its cell surface, including lipid extraction, degradation, and transport steps for the lipid antigen both prior to and following assembly with the MHC protein complex. The lipid antigen may originate from an endogenous or exogenous source of lipid. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015943", "l": "formate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901183", "l": "positive regulation of camalexin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of camalexin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075314", "l": "regulation of basidium development", "d": ["Any process that modulates the frequency, rate or extent of basidium development, a process that leads to the formation of a basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033469", "l": "gibberellin 12 metabolic process", "d": ["The chemical reactions and pathways involving gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031627", "l": "telomeric loop formation", "d": ["The process in which linear telomeric DNA is remodeled into duplex loops, by the invasion of a 3' single-stranded overhang into the duplex region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0062225", "l": "negative regulation of somatic muscle development", "d": ["Any process that decreases the rate, frequency or extent of somatic muscle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060691", "l": "epithelial cell maturation involved in salivary gland development", "d": ["The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015972", "l": "guanosine pentaphosphate metabolic process", "d": ["The chemical reactions and pathways involving guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032644", "l": "regulation of fractalkine production", "d": ["Any process that modulates the frequency, rate, or extent of fractalkine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090050", "l": "positive regulation of cell migration involved in sprouting angiogenesis", "d": ["Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120047", "l": "positive regulation of protein localization to medial cortical node", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to a medial cortical node."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904099", "l": "negative regulation of protein O-linked glycosylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein O-linked glycosylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042140", "l": "late meiotic recombination nodule assembly", "d": ["During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during pachytene. Involved in the catalysis crossing over."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070471", "l": "uterine smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the uterus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The uterus is a muscular organ of the female mammal for containing and usually for nourishing the young during development prior to birth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0006942", "l": "regulation of striated muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of striated muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0072048", "l": "renal system pattern specification", "d": ["Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071947", "l": "protein deubiquitination involved in ubiquitin-dependent protein catabolic process", "d": ["The removal of one or more ubiquitin groups from a protein as part of a process of ubiquitin-dependent protein catabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019610", "l": "3-hydroxyphenylacetate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045850", "l": "positive regulation of nurse cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of nurse cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042751", "l": "estivation", "d": ["Any process in which an organism enters and maintains a period of dormancy, similar to hibernation, but that occurs during the summer. It insulates against heat to prevent the harmful effects of the season."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000883", "l": "positive regulation of starch catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of starch catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140636", "l": "copper import into the mitochondrion", "d": ["The process in which copper is transported from the cytosol into the mitochondrial matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904553", "l": "negative regulation of chemotaxis to arachidonic acid", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chemotaxis to arachidonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000668", "l": "regulation of dendritic cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039580", "l": "suppression by virus of host PKR signaling", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (Protein Kinase regulated by RNA) signaling. Host PKR signaling includes targets such as the translation initiation factor eIF2alpha, inhibiting protein synthesis as an antiviral response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006054", "l": "N-acetylneuraminate metabolic process", "d": ["The chemical reactions and pathways involving N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903005", "l": "negative regulation of protein K63-linked deubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked deubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060652", "l": "mammary gland cord morphogenesis", "d": ["The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901246", "l": "regulation of lung ciliated cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.693529410615042", "identifiers": [{"i": "GO:0030031", "l": "cell projection assembly", "d": ["Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001301", "l": "lipoxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a lipoxin. A lipoxin is a non-classic eicosanoid and signalling molecule that has four conjugated double bonds and is derived from arachidonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097067", "l": "cellular response to thyroid hormone stimulus", "d": ["A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0032950", "l": "regulation of beta-glucan metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving beta-glucans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000332", "l": "regulation of blood microparticle formation", "d": ["Any process that modulates the frequency, rate or extent of blood microparticle formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048481", "l": "plant ovule development", "d": ["The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000770", "l": "peptide pheromone export", "d": ["The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0071312", "l": "cellular response to alkaloid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070221", "l": "sulfide oxidation, using sulfide:quinone oxidoreductase", "d": ["A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide:quinone oxidoreductase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048052", "l": "R1/R6 cell differentiation", "d": ["The process in which relatively unspecialized cells acquire the specialized features of R1 and R6 photoreceptors. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0014071", "l": "response to cycloalkane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0036161", "l": "calcitonin secretion", "d": ["The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052088", "l": "symbiont defense to host-produced jasmonic acid", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010887", "l": "negative regulation of cholesterol storage", "d": ["Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072222", "l": "metanephric early distal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904481", "l": "response to tetrahydrofolate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033092", "l": "positive regulation of immature T cell proliferation in thymus", "d": ["Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000517", "l": "regulation of T-helper 1 cell activation", "d": ["Any process that modulates the frequency, rate or extent of T-helper 1 cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904845", "l": "cellular response to L-glutamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048322", "l": "axial mesodermal cell fate commitment", "d": ["The process in which a cell becomes committed to become an axial mesoderm cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021609", "l": "accessory nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the accessory nerve This process pertains to the physical shaping of a rudimentary structure. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019254", "l": "carnitine metabolic process, CoA-linked", "d": ["The chemical reactions and pathways involving carnitine, where metabolism is linked to CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1901159", "l": "xylulose 5-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of xylulose 5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902999", "l": "negative regulation of phospholipid efflux", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid efflux."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.069090159478471", "identifiers": [{"i": "GO:0120036", "l": "plasma membrane bounded cell projection organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0017085", "l": "response to insecticide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900100", "l": "positive regulation of plasma cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of plasma cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.686661695795102", "identifiers": [{"i": "GO:1902531", "l": "regulation of intracellular signal transduction", "d": ["Any process that modulates the frequency, rate or extent of intracellular signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0016482", "l": "cytosolic transport", "d": ["The directed movement of substances or organelles within the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048085", "l": "adult chitin-containing cuticle pigmentation", "d": ["Establishment of the adult pattern of pigmentation in the chitin-containing cuticle of an organism. An example of this is the adult cuticle pigmentation process in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060085", "l": "smooth muscle relaxation of the bladder outlet", "d": ["A process in which the extent of smooth muscle contraction is reduced in the bladder outlet that contributes to the expulsion of urine from the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043606", "l": "formamide metabolic process", "d": ["The chemical reactions and pathways involving formamide, the simplest amide, HCONH2, derived from formic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904302", "l": "negative regulation of maternal process involved in parturition", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maternal process involved in parturition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0002275", "l": "myeloid cell activation involved in immune response", "d": ["A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021798", "l": "forebrain dorsal/ventral pattern formation", "d": ["The formation of specific regional progenitor domains along the dorsal-ventral axis in the developing forebrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0009237", "l": "siderophore metabolic process", "d": ["The chemical reactions and pathways involving siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0031537", "l": "regulation of anthocyanin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0021895", "l": "cerebral cortex neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099564", "l": "modification of synaptic structure, modulating synaptic transmission", "d": ["Any process that modulates synaptic transmission via modification of the structure of the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901550", "l": "regulation of endothelial cell development", "d": ["Any process that modulates the frequency, rate or extent of endothelial cell development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000105", "l": "positive regulation of DNA-templated DNA replication", "d": ["Any process that activates or increases the frequency, rate or extent of DNA-templated DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072144", "l": "glomerular mesangial cell development", "d": ["The process whose specific outcome is the progression of a glomerular mesangial cell in the kidney over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902343", "l": "regulation of maltose transport", "d": ["Any process that modulates the frequency, rate or extent of maltose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003250", "l": "regulation of cell proliferation involved in heart valve morphogenesis", "d": ["Any process that modulates the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0017015", "l": "regulation of transforming growth factor beta receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035445", "l": "borate transmembrane transport", "d": ["The process in which borate is transported across a membrane. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050689", "l": "negative regulation of defense response to virus by host", "d": ["Any host process that results in the inhibition of antiviral immune response mechanisms, thereby facilitating viral replication. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990090", "l": "cellular response to nerve growth factor stimulus", "d": ["A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034477", "l": "U6 snRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a U6 snRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061253", "l": "mesonephric glomerular parietal epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002174", "l": "mammary stem cell proliferation", "d": ["The expansion of a mammary stem cell population by cell division. Mammary stem cells are a source of cells for growth of the mammary gland during puberty and gestation. These cells can give rise to both the luminal and myoepithelial cell types of the gland, and can regenerate the entire organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048079", "l": "regulation of cuticle pigmentation", "d": ["Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0002385", "l": "mucosal immune response", "d": ["An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046100", "l": "hypoxanthine metabolic process", "d": ["The chemical reactions and pathways involving hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000268", "l": "positive regulation of blood coagulation, intrinsic pathway", "d": ["Any process that activates or increases the frequency, rate or extent of blood coagulation, intrinsic pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035335", "l": "peptidyl-tyrosine dephosphorylation", "d": ["The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905622", "l": "negative regulation of leaf development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leaf development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901808", "l": "capsanthin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of capsanthin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001697", "l": "histamine-induced gastric acid secretion", "d": ["The regulated release of gastric acid induced by the interaction of histamine with H2 type receptor receptors with subsequent activation of adenylate cyclase and elevation of intracellular cyclic AMP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072128", "l": "renal capsule morphogenesis", "d": ["The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021762", "l": "substantia nigra development", "d": ["The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.004905482618113", "identifiers": [{"i": "GO:0006506", "l": "GPI anchor biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0043299", "l": "leukocyte degranulation", "d": ["The regulated exocytosis of secretory granules by a leukocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.987832356016085", "identifiers": [{"i": "GO:0030216", "l": "keratinocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.980302069293842", "identifiers": [{"i": "GO:0061539", "l": "octopamine secretion", "d": ["The controlled release of octopamine by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003289", "l": "atrial septum primum morphogenesis", "d": ["The process in which anatomical structure of an atrial septum primum is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042690", "l": "negative regulation of crystal cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of crystal cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904452", "l": "negative regulation of potassium:proton exchanging ATPase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0001977", "l": "renal system process involved in regulation of blood volume", "d": ["A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042832", "l": "defense response to protozoan", "d": ["Reactions triggered in response to the presence of a protozoan that act to protect the cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006429", "l": "leucyl-tRNA aminoacylation", "d": ["The process of coupling leucine to leucyl-tRNA, catalyzed by leucyl-tRNA synthetase. The leucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a leucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903921", "l": "regulation of protein processing in phagocytic vesicle", "d": ["Any process that modulates the frequency, rate or extent of protein processing in phagocytic vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904673", "l": "negative regulation of somatic stem cell population maintenance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell population maintenance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002406", "l": "antigen sampling by M cells in mucosal-associated lymphoid tissue", "d": ["The process of antigen samples carried out by M cells in the mucosal-associated lymphoid tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002604", "l": "regulation of dendritic cell antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0008360", "l": "regulation of cell shape", "d": ["Any process that modulates the surface configuration of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0000968", "l": "tRNA exon ligation", "d": ["An RNA exon ligation process that rejoins two exons of a pre-tRNA which has had the intron removed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903535", "l": "negative regulation of lactose biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lactose biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000433", "l": "positive regulation of cytokinesis, actomyosin contractile ring assembly", "d": ["Any process that activates or increases the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.837016147763222", "identifiers": [{"i": "GO:0048771", "l": "tissue remodeling", "d": ["The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001925", "l": "negative regulation of B-1 B cell differentiation", "d": ["Any process that stops, prevents, or reduces the rate of B-1 B cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010929", "l": "positive regulation of auxin mediated signaling pathway", "d": ["Any process that increases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014730", "l": "skeletal muscle regeneration at neuromuscular junction", "d": ["The regrowth of muscle tissue to repair injured or damaged muscle fibers in the postnatal stage at the neuromuscular junction. Regeneration of neuromuscular junctions occurs in an orderly way and relies on communication between nerve and muscle. Skeletal myofibers regenerate after injury and form neuro-muscular junctions with motor axons similar to normal ones. Regenerating myofibers develop within the basal lamina sheaths (satellite cells) of original myofibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060884", "l": "clearance of cells from fusion plate", "d": ["The morphogenetic process in which cells are removed from the inner loop of a semicircular canal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902053", "l": "regulation of neosartoricin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of neosartoricin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060551", "l": "regulation of fructose 1,6-bisphosphate metabolic process", "d": ["Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021967", "l": "corticospinal neuron axon guidance through the cerebral cortex", "d": ["The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed from its cell body in layer V through the cerebral cortex in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033668", "l": "suppression by symbiont of host apoptotic process", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150128", "l": "negative regulation of interleukin-33 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-33 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048195", "l": "Golgi membrane priming complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a membrane priming complex. An incoming coat component recognizes both GTPase and a membrane protein to form the priming complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042307", "l": "positive regulation of protein import into nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051914", "l": "positive regulation of synaptic plasticity by chemical substance", "d": ["The process in which a chemical substance increases synaptic plasticity, the ability of synapses to change as circumstances require."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.415093686714229", "identifiers": [{"i": "GO:0035107", "l": "appendage morphogenesis", "d": ["The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0030903", "l": "notochord development", "d": ["The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090379", "l": "secondary cell wall biogenesis involved in seed trichome differentiation", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall of seed trichomes after cell expansion is complete."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075210", "l": "disruption of host cAMP-mediated signal transduction", "d": ["Any process in which the symbiont organism interferes with cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902955", "l": "positive regulation of early endosome to recycling endosome transport", "d": ["Any process that activates or increases the frequency, rate or extent of early endosome to recycling endosome transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903334", "l": "positive regulation of protein folding", "d": ["Any process that activates or increases the frequency, rate or extent of protein folding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007482", "l": "haltere development", "d": ["The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034161", "l": "positive regulation of toll-like receptor 8 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 8 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072149", "l": "podocyte cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.214594383375484", "identifiers": [{"i": "GO:0022008", "l": "neurogenesis", "d": ["Generation of cells within the nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070801", "l": "positive regulation of conidiophore stalk development", "d": ["Any process that activates or increases the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003291", "l": "atrial septum intermedium morphogenesis", "d": ["The process in which anatomical structure of an atrial septum intermedium is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051368", "l": "peptidyl-threonine octanoylation", "d": ["The octanoylation of peptidyl-threonine to form peptidyl-O3-octanoyl-L-threonine, typical of the protein ghrelin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0097061", "l": "dendritic spine organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dendritic spine. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0000479", "l": "endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with three genes, in this order, are produced in the nuclei of many eukaryotic species, including S. cerevisiae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903936", "l": "cellular response to sodium arsenite", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071291", "l": "cellular response to selenium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033183", "l": "negative regulation of histone ubiquitination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of a ubiquitin group to a histone protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060405", "l": "regulation of penile erection", "d": ["Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.116918913335823", "identifiers": [{"i": "GO:0046785", "l": "microtubule polymerization", "d": ["The addition of tubulin heterodimers to one or both ends of a microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035130", "l": "post-embryonic pectoral fin morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.477464033556856", "identifiers": [{"i": "GO:0007010", "l": "cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019623", "l": "atrazine catabolic process to urea", "d": ["The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into urea."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0032975", "l": "amino acid transmembrane import into vacuole", "d": ["The directed movement of amino acids into the vacuole across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002017", "l": "regulation of blood volume by renal aldosterone", "d": ["The process in which the hormone aldosterone decreases the rate of diuresis and natriuresis resulting in increased blood volume."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000149", "l": "negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905596", "l": "negative regulation of low-density lipoprotein particle receptor binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein particle receptor binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0034757", "l": "negative regulation of iron ion transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0015774", "l": "polysaccharide transport", "d": ["The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0000092", "l": "mitotic anaphase B", "d": ["The cell cycle phase during which the polar microtubules elongate and the two poles of the spindle move farther apart as part of mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032458", "l": "slow endocytic recycling", "d": ["The directed movement of membrane-bounded vesicles from deep (non-peripheral) compartments endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120264", "l": "regulation of chromosome attachment to the nuclear envelope", "d": ["Any process that modulates the frequency, rate, extent or location of chromosome attachment to the nuclear envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051684", "l": "maintenance of Golgi location", "d": ["Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0071423", "l": "malate transmembrane transport", "d": ["A process in which a malate ion is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080119", "l": "ER body organization", "d": ["A process that is carried out at the cellular level which results in the formation of ER (endoplasmic reticulum) body. ER body is a compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075311", "l": "positive regulation of sporangium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903251", "l": "multi-ciliated epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000766", "l": "negative adaptation of signaling pathway by response to pheromone involved in pheromone-induced unidirectional conjugation", "d": ["In organisms that undergo pheromone-induced unidirectional conjugation, the process involved in desensitization following exposure to pheromone stimulus that acts to down-regulate further stimulation or block initial conjugation responses."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003067", "l": "circadian regulation of systemic arterial blood pressure by hormone", "d": ["The process in which hormones modulate the force with which blood passes through the circulatory system contributing to different values of blood pressure oscillating with a regularity of approximately 24 hours. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090332", "l": "stomatal closure", "d": ["The process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006657", "l": "CDP-choline pathway", "d": ["The phosphatidylcholine biosynthetic process that begins with the phosphorylation of choline and ends with the combination of CDP-choline with diacylglycerol to form phosphatidylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045741", "l": "positive regulation of epidermal growth factor-activated receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of EGF-activated receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905699", "l": "regulation of xenobiotic detoxification by transmembrane export across the plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0042276", "l": "error-prone translesion synthesis", "d": ["The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044075", "l": "modulation by symbiont of host vacuole organization", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of vacuole organization in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.927964040871231", "identifiers": [{"i": "GO:0046631", "l": "alpha-beta T cell activation", "d": ["The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062127", "l": "fatty acid primary amide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of primary fatty amides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045019", "l": "negative regulation of nitric oxide biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0043462", "l": "regulation of ATP-dependent activity", "d": ["Any process that modulates the rate of an ATP-dependent activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000121", "l": "regulation of removal of superoxide radicals", "d": ["Any process that modulates the frequency, rate or extent of removal of superoxide radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019522", "l": "ketogluconate metabolic process", "d": ["The chemical reactions and pathways involving ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0099163", "l": "synaptic signaling by nitric oxide", "d": ["Cell-cell signaling to or from a synapse, mediated by nitric oxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009154", "l": "purine ribonucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036453", "l": "transitive RNA interference", "d": ["An RNA interference where the silencing signal spreads along the target mRNA in a 5' or 3' direction, outside of the initial target sequence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006676", "l": "mannosyl diphosphorylinositol ceramide metabolic process", "d": ["The chemical reactions and pathways involving mannosyl diphosphorylinositol ceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains two phosphoryl (-P(O)=) groups and a mannose derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905376", "l": "negative regulation of cytochrome-c oxidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cytochrome-c oxidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060045", "l": "positive regulation of cardiac muscle cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1900122", "l": "positive regulation of receptor binding", "d": ["Any process that activates or increases the frequency, rate or extent of a protein or other molecule binding to a receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2001308", "l": "gliotoxin metabolic process", "d": ["The chemical reactions and pathways involving the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035170", "l": "lymph gland crystal cell differentiation", "d": ["The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904832", "l": "negative regulation of removal of superoxide radicals", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of removal of superoxide radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035229", "l": "positive regulation of glutamate-cysteine ligase activity", "d": ["Any process that activates or increases the activity of glutamate-cysteine ligase, typically by lowering its sensitivity to inhibition by glutathione and by increasing its affinity for glutamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0072414", "l": "response to mitotic cell cycle checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of mitotic cell cycle checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0050763", "l": "depsipeptide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0048102", "l": "autophagic cell death", "d": ["A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905673", "l": "positive regulation of lysosome organization", "d": ["Any process that activates or increases the frequency, rate or extent of lysosome organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0042435", "l": "indole-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033485", "l": "cyanidin 3-O-glucoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyanidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007342", "l": "fusion of sperm to egg plasma membrane involved in single fertilization", "d": ["The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031025", "l": "equatorial microtubule organizing center disassembly", "d": ["The process in which the equatorial microtubule organizing center is disassembled at the end of mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.685364931984026", "identifiers": [{"i": "GO:0009267", "l": "cellular response to starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060513", "l": "prostatic bud formation", "d": ["The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0055024", "l": "regulation of cardiac muscle tissue development", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle tissue development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900344", "l": "positive regulation of methane biosynthetic process from dimethyl sulfide", "d": ["Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0017006", "l": "protein-tetrapyrrole linkage", "d": ["The covalent linking of a tetrapyrrole to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097320", "l": "plasma membrane tubulation", "d": ["A membrane tubulation process occurring in a plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046341", "l": "CDP-diacylglycerol metabolic process", "d": ["The chemical reactions and pathways involving CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. It is a common intermediate in phospholipid biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031153", "l": "slug development involved in sorocarp development", "d": ["The process whose specific outcome is the progression of the slug over time, from its formation to the mature structure. Slug development begins when the aggregate rises upwards to form a finger-shaped structure and ends when culmination begins. Slug development begins after aggregation and ends before culmination in sorocarp development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0033367", "l": "protein localization to mast cell secretory granule", "d": ["A process in which a protein is transported to, or maintained in, a location within a secretory granule in a mast cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035457", "l": "cellular response to interferon-alpha", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001548", "l": "follicular fluid formation in ovarian follicle antrum", "d": ["The menstrual cycle process that results in the formation of one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells during the various stages of oogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034630", "l": "RITS complex localization", "d": ["Any process in which a RITS complex is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0072244", "l": "metanephric glomerular epithelium development", "d": ["The process whose specific outcome is the progression of the metanephric glomerular epithelium over time, from its formation to the mature structure. The metanephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the metanephros. The metanephric glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032626", "l": "interleukin-22 production", "d": ["The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060017", "l": "parathyroid gland development", "d": ["The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.684842734364032", "identifiers": [{"i": "GO:0009719", "l": "response to endogenous stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002505", "l": "antigen processing and presentation of polysaccharide antigen via MHC class II", "d": ["The process in which an antigen-presenting cell expresses a polysaccharide antigen on its cell surface in association with an MHC class II protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046844", "l": "chorion micropyle formation", "d": ["Establishment of the micropyle, a single cone-shaped specialization of the chorion that allows sperm entry into the egg prior to fertilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904830", "l": "negative regulation of aortic smooth muscle cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900872", "l": "pentadec-1-ene metabolic process", "d": ["The chemical reactions and pathways involving pentadec-1-ene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044726", "l": "epigenetic programing of female pronucleus", "d": ["The global programming of epigenetic modifications in the female pronucleus of the newly fertilized zygote. The maternal genome is protected from global DNA demethylation before the first division of the zygote, and instead undergoes passive, replication-dependent demethylation during early embryogenesis, arising from inhibition of the DNA maintenance methyltransferase Dnmt1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072663", "l": "establishment of protein localization to peroxisome", "d": ["The directed movement of a protein to a specific location in a peroxisome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990813", "l": "meiotic centromeric cohesion protection", "d": ["The process in which the association between sister chromatids of a replicated chromosome centromeric region is maintained during homologous chromosome segregation after cohesin is cleaved by separase along the arm regions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001661", "l": "conditioned taste aversion", "d": ["A conditioned aversion to a specific chemical compound as a result of that compound being coupled with a noxious stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009192", "l": "deoxyribonucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090310", "l": "negative regulation of DNA methylation-dependent heterochromatin formation", "d": ["Any process that decreases the rate, frequency, or extent of DNA methylation-dependent heterochromatin formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071490", "l": "cellular response to far red light", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070593", "l": "dendrite self-avoidance", "d": ["The process in which dendrites recognize and avoid contact with sister dendrites from the same cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0097479", "l": "synaptic vesicle localization", "d": ["Any process in which a synaptic vesicle or vesicles are transported to, and/or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072689", "l": "MCM complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an MCM complex, a hexameric protein complex required for the initiation and regulation of DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019502", "l": "L-proline betaine metabolic process", "d": ["The chemical reactions and pathways involving stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline found in alfalfa, chrysanthemum, and citrus plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048719", "l": "epistomal sclerite morphogenesis", "d": ["The process in which the anatomical structures of the epistomal sclerite are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901666", "l": "positive regulation of NAD+ ADP-ribosyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007141", "l": "male meiosis I", "d": ["A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051295", "l": "establishment of meiotic spindle localization", "d": ["The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900693", "l": "negative regulation of (+)-kotanin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of (+)-kotanin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.442476542024195", "identifiers": [{"i": "GO:0071168", "l": "protein localization to chromatin", "d": ["Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902148", "l": "positive regulation of response to cytokinesis checkpoint signaling", "d": ["Any process that activates or increases the frequency, rate or extent of response to cytokinesis checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000983", "l": "regulation of ATP citrate synthase activity", "d": ["Any process that modulates the frequency, rate or extent of ATP citrate synthase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901432", "l": "negative regulation of response to cycloalkane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to cycloalkane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.161881760686384", "identifiers": [{"i": "GO:0072676", "l": "lymphocyte migration", "d": ["The movement of a lymphocyte within or between different tissues and organs of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000493", "l": "negative regulation of interleukin-18-mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-18-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0050732", "l": "negative regulation of peptidyl-tyrosine phosphorylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0032781", "l": "positive regulation of ATP-dependent activity", "d": ["Any process that activates or increases the rate of an ATP-dependent activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000621", "l": "regulation of DNA replication termination", "d": ["Any process that modulates the frequency, rate or extent of DNA replication termination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:2001138", "l": "regulation of phospholipid transport", "d": ["Any process that modulates the frequency, rate or extent of phospholipid transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045299", "l": "otolith mineralization", "d": ["The precipitation of specific crystal forms of calcium carbonate with extracellular matrix proteins in the otolith organs of the vertebrate inner ear."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905188", "l": "positive regulation of metaphase/anaphase transition of meiosis I", "d": ["Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901821", "l": "alpha-zeacarotene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alpha-zeacarotene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010063", "l": "positive regulation of trichoblast fate specification", "d": ["Any process that induces or promotes trichoblast fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090496", "l": "mesenchyme migration involved in limb bud formation", "d": ["The migration of mesenchymal tissue that contributes to the formation of a limb bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0032341", "l": "aldosterone metabolic process", "d": ["The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018014", "l": "N-terminal peptidyl-methionine methylation", "d": ["The methylation of the N-terminal methionine of proteins to form the derivative N-methyl-L-methionine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900034", "l": "regulation of cellular response to heat", "d": ["Any process that modulates the frequency, rate or extent of cellular response to heat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002727", "l": "regulation of natural killer cell cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035873", "l": "lactate transmembrane transport", "d": ["The process in which lactate is transported across a membrane. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046331", "l": "lateral inhibition", "d": ["Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035338", "l": "long-chain fatty-acyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a long-chain fatty-acyl-CoA any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042271", "l": "susceptibility to natural killer cell mediated cytotoxicity", "d": ["The process of causing a cell to become susceptible to natural killer cell mediated cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061153", "l": "trachea gland development", "d": ["The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000974", "l": "negative regulation of pro-B cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0032641", "l": "lymphotoxin A production", "d": ["The chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901158", "l": "neomycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of neomycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032827", "l": "negative regulation of natural killer cell differentiation involved in immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106110", "l": "vomitoxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of type B trichothecene vomitoxin, also known as deoxynivalenol, a poisonous substance produced by some species of fungi and predominantly occurs in grains such as wheat, barley and oats."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120270", "l": "regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts", "d": ["Any process that modulates the rate, frequency, or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0009110", "l": "vitamin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099076", "l": "mitochondrion to peroxisome transport", "d": ["Transport from the mitochondrion to the peroxisome, mediated by mitochondrion-derived vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0141061", "l": "disruption of cell in another organism", "d": ["The disruption of the a cell of another organism, leading to damage or temporary subversion of that cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061967", "l": "establishment of left sidedness", "d": ["The initial formation of the type asymmetry in an organism's body plan or part of an organism that established the pattern characteristic to its left side."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905226", "l": "regulation of adhesion of symbiont to host epithelial cell", "d": ["Any process that modulates the frequency, rate or extent of adhesion of symbiont to host epithelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033488", "l": "cholesterol biosynthetic process via 24,25-dihydrolanosterol", "d": ["The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate 24,25-dihydrolanosterol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905220", "l": "negative regulation of platelet formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of platelet formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106227", "l": "peptidyl-lysine glutarylation", "d": ["The glutarylation of a lysine residue in a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0060142", "l": "regulation of syncytium formation by plasma membrane fusion", "d": ["Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071514", "l": "genomic imprinting", "d": ["The establishment of epigenetic modifications (imprints) during gametogenesis, and propagation of these imprints during the organism's life. Genomic imprinting leads to an asymmetry between the maternal and paternal alleles and differential expression of the corresponding alleles. This can happen through heterochromatin formation or differential chromatin loop formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0045622", "l": "regulation of T-helper cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of T-helper cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048370", "l": "lateral mesoderm formation", "d": ["The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046960", "l": "sensitization", "d": ["An increased in a behavioral response to a repeated stimulus. For example, a shock to the tail of the marine snail Aplysia, to which the snail responds by withdrawing its gill, will result in increased gill withdrawal the next time the skin is touched."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060056", "l": "mammary gland involution", "d": ["The tissue remodeling that removes differentiated mammary epithelia during weaning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0043942", "l": "negative regulation of sexual sporulation resulting in formation of a cellular spore", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031367", "l": "N-terminal peptidyl-glutamine deamination", "d": ["The removal of an amino group from the side chain of an N-terminal glutamine residue of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0042273", "l": "ribosomal large subunit biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003217", "l": "cardiac right atrium formation", "d": ["The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0045828", "l": "positive regulation of isoprenoid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090186", "l": "regulation of pancreatic juice secretion", "d": ["Any process that modulates the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036273", "l": "response to statin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC:1.1.1.34/EC:1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051556", "l": "leucoanthocyanidin metabolic process", "d": ["The chemical reactions and pathways involving leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0060688", "l": "regulation of morphogenesis of a branching structure", "d": ["Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021646", "l": "vagus nerve formation", "d": ["The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140880", "l": "terrein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of terrein, a fungal metabolite with ecological, antimicrobial, antiproliferative, and antioxidative activities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060074", "l": "synapse maturation", "d": ["The process that organizes a synapse so that it attains its fully functional state. Synaptic maturation plays a critical role in the establishment of effective synaptic connections in early development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902177", "l": "positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060059", "l": "embryonic retina morphogenesis in camera-type eye", "d": ["The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the embryonic life stage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000307", "l": "regulation of tumor necrosis factor (ligand) superfamily member 11 production", "d": ["Any process that modulates the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904628", "l": "cellular response to phorbol 13-acetate 12-myristate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000585", "l": "positive regulation of platelet-derived growth factor receptor-alpha signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903932", "l": "regulation of DNA primase activity", "d": ["Any process that modulates the frequency, rate or extent of DNA primase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0021696", "l": "cerebellar cortex morphogenesis", "d": ["The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140147", "l": "zinc ion export from vacuole", "d": ["The directed movement of zinc ions from inside the vacuole across the vacuolar membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903979", "l": "negative regulation of microglial cell activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006420", "l": "arginyl-tRNA aminoacylation", "d": ["The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of an alanine accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015724", "l": "formate transport", "d": ["The directed movement of formate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034035", "l": "purine ribonucleoside bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042668", "l": "auditory receptor cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900224", "l": "positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry", "d": ["Any process that activates or increases the frequency, rate or extent of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900179", "l": "positive regulation of aflatoxin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of aflatoxin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.744066580938323", "identifiers": [{"i": "GO:1902410", "l": "mitotic cytokinetic process", "d": ["Any cytokinetic process that is involved in mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090233", "l": "negative regulation of spindle checkpoint", "d": ["Any process that decreases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097307", "l": "response to farnesol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.261443428098588", "identifiers": [{"i": "GO:0030203", "l": "glycosaminoglycan metabolic process", "d": ["The chemical reactions and pathways involving glycosaminoglycans, any of a group of polysaccharides that contain amino sugars."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099006", "l": "viral entry via permeabilization of endosomal membrane", "d": ["The entry of a non-enveloped virus into a host eukaryotic cell, following endocytosis, via permeabilization of the endosomal membrane by membrane penetration protein(s) associated with the viral capsid. In some cases, viral membrane-penetration protein require first to be activated to display its membrane penetrating activity. Activation can be due to receptor binding or the acidic pH of the endosomal lumen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035294", "l": "determination of wing disc primordium", "d": ["Allocation of embryonic cells to the wing disc founder populations, groups of cells that are committed to contribute to the formation of a wing imaginal disc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150118", "l": "negative regulation of cell-substrate junction organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell-substrate junction organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901088", "l": "benzylpenicillin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of benzylpenicillin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009631", "l": "cold acclimation", "d": ["Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.071082486141265", "identifiers": [{"i": "GO:1902742", "l": "apoptotic process involved in development", "d": ["Any apoptotic process that is involved in anatomical structure development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031069", "l": "hair follicle morphogenesis", "d": ["The process in which the anatomical structures of the hair follicle are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0015671", "l": "oxygen transport", "d": ["The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903648", "l": "positive regulation of chlorophyll catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of chlorophyll catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031366", "l": "N-terminal peptidyl-asparagine deamination", "d": ["The removal of an amino group from the side chain of an N-terminal asparagine residue of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048289", "l": "isotype switching to IgE isotypes", "d": ["The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002882", "l": "positive regulation of chronic inflammatory response to non-antigenic stimulus", "d": ["Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097480", "l": "establishment of synaptic vesicle localization", "d": ["The directed movement of a synaptic vesicle or vesicles to a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019417", "l": "sulfur oxidation", "d": ["The chemical reactions and pathways resulting the addition of oxygen to elemental sulfur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019241", "l": "citrulline catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0006958", "l": "complement activation, classical pathway", "d": ["Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0072564", "l": "blood microparticle formation", "d": ["The cellular component organization process in which microparticles bud off from a parent cell. A microparticle is a phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902799", "l": "regulation of phosphodiesterase I activity", "d": ["Any process that modulates the frequency, rate or extent of phosphodiesterase I activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0043692", "l": "monoterpene metabolic process", "d": ["The chemical reactions and pathways involving monoterpenes, terpenes with a C10 structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0042756", "l": "drinking behavior", "d": ["The specific behavior of an organism relating to the intake of liquids, especially water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010549", "l": "regulation of membrane disassembly", "d": ["Any process that modulates the frequency, rate or extent of membrane disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0010460", "l": "positive regulation of heart rate", "d": ["Any process that activates or increases the frequency or rate of heart contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0042173", "l": "regulation of sporulation resulting in formation of a cellular spore", "d": ["Any process that modulates the frequency, rate or extent of spore formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905802", "l": "regulation of cellular response to manganese ion", "d": ["Any process that modulates the frequency, rate or extent of cellular response to manganese ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0001982", "l": "baroreceptor response to decreased systemic arterial blood pressure", "d": ["The lowering of the number of nerve impulses from baroreceptors as a result of decreased stretch of an artery that results in an increased in sympathetic nerve impulses to peripheral blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044663", "l": "establishment or maintenance of cell type involved in phenotypic switching", "d": ["A cellular process of the specification, formation or maintenance of an alternative cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007270", "l": "neuron-neuron synaptic transmission", "d": ["The process of synaptic transmission from a neuron to another neuron across a synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060535", "l": "trachea cartilage morphogenesis", "d": ["The process in which the anatomical structures of cartilage in the trachea are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048560", "l": "establishment of anatomical structure orientation", "d": ["The process that determines the orientation of an anatomical structure with reference to an axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070392", "l": "detection of lipoteichoic acid", "d": ["The series of events in which a lipoteichoic acid stimulus is received by a cell and converted into a molecular signal; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021950", "l": "chemorepulsion involved in precerebellar neuron migration", "d": ["The creation and reception of signals that repel a precerebellar neuron as a component of the process of tangential migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.777124918050973", "identifiers": [{"i": "GO:0044355", "l": "clearance of foreign intracellular DNA", "d": ["A defense process that protects an organism from invading foreign DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009179", "l": "purine ribonucleoside diphosphate metabolic process", "d": ["The chemical reactions and pathways involving purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036259", "l": "aerobic raffinose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of raffinose that occur in the presence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080127", "l": "fruit septum development", "d": ["The process whose specific outcome is the progression of the fruit septum over time, from its formation to the mature structure. The fruit septum is a thin partition or membrane that divides a cavity or a mass of tissue in the fruit."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0052782", "l": "amino disaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.497098305844077", "identifiers": [{"i": "GO:0006644", "l": "phospholipid metabolic process", "d": ["The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009879", "l": "determination of radial symmetry", "d": ["The establishment of an organism's body plan or a part of an organism such that it is symmetric around a central axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905913", "l": "negative regulation of calcium ion export across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion export across the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0032899", "l": "regulation of neurotrophin production", "d": ["Any process that modulates the frequency, rate, or extent of production of a neurotrophin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902324", "l": "positive regulation of methyl-branched fatty acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of methyl-branched fatty acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019677", "l": "NAD catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; catabolism may be of either the oxidized form, NAD, or the reduced form, NADH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018954", "l": "pentaerythritol tetranitrate metabolic process", "d": ["The chemical reactions and pathways involving pentaerythritol tetranitrate, C(CH2-O-NO2)4, a substance produced for use as an explosive and a vasodilator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060636", "l": "negative regulation of (1->3)-beta-D-glucan biosynthetic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030033", "l": "microvillus assembly", "d": ["Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901556", "l": "response to candesartan", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a candesartan stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032148", "l": "activation of protein kinase B activity", "d": ["Any process that initiates the activity of the inactive enzyme protein kinase B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1904180", "l": "negative regulation of membrane depolarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010946", "l": "regulation of meiotic joint molecule formation", "d": ["Any process that modulates the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0016558", "l": "protein import into peroxisome matrix", "d": ["The import of proteins into the peroxisomal matrix. A peroxisome targeting signal (PTS) binds to a soluble receptor protein in the cytosol, and the resulting complex then binds to a receptor protein in the peroxisome membrane and is imported. The cargo protein is then released into the peroxisome matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072141", "l": "renal interstitial fibroblast development", "d": ["The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140976", "l": "defense response against perturbation of plasma membrane integrity", "d": ["The cellular processes and signaling pathways by which a cell responds to disruption of the integrity of its plasma membrane by another organism. Some toxins produced by other organisms can form pores in membranes, or affect the membrane permeability."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900182", "l": "positive regulation of protein localization to nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071834", "l": "mating pheromone secretion", "d": ["The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that contributes to a process of sexual reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097213", "l": "regulation of lysosomal membrane permeability", "d": ["Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060054", "l": "positive regulation of epithelial cell proliferation involved in wound healing", "d": ["Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006965", "l": "positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria", "d": ["Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071866", "l": "negative regulation of apoptotic process in bone marrow cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0045445", "l": "myoblast differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036349", "l": "galactose-specific flocculation", "d": ["The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to galactose residues on the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903075", "l": "pyridoxine import across plasma membrane", "d": ["The directed movement of pyridoxine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0002663", "l": "positive regulation of B cell tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of B cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0007616", "l": "long-term memory", "d": ["The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0016579", "l": "protein deubiquitination", "d": ["The removal of one or more ubiquitin groups from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901111", "l": "actinorhodin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of actinorhodin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031664", "l": "regulation of lipopolysaccharide-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0008154", "l": "actin polymerization or depolymerization", "d": ["Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0060846", "l": "blood vessel endothelial cell fate commitment", "d": ["The commitment of a cell to a blood vessel endothelial cell fate and its capacity to differentiate into a blood vessel endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098864", "l": "modification by symbiont of host tight cell-cell junction", "d": ["The process in which a symbiont organism effects a change in the structure or function of its host tight junction, a cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1990274", "l": "mitotic actomyosin contractile ring disassembly", "d": ["Any disaggregation of an actomyosin contractile ring into its constituent components that is involved in a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002636", "l": "positive regulation of germinal center formation", "d": ["Any process that activates or increases the frequency, rate, or extent of germinal center formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061509", "l": "asymmetric protein localization to old mitotic spindle pole body", "d": ["Any process in which a protein is transported to, or maintained to the old mitotic spindle pole body resulting in its being distributed asymmetrically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032343", "l": "aldosterone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0110065", "l": "regulation of interphase mitotic telomere clustering", "d": ["Any process that modulates the frequency, rate or extent of mitotic telomere clustering during interphase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0034407", "l": "cell wall (1->3)-beta-D-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.594043123901756", "identifiers": [{"i": "GO:0051347", "l": "positive regulation of transferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062172", "l": "lutein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lutein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0090231", "l": "regulation of spindle checkpoint", "d": ["Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0045704", "l": "regulation of salivary gland boundary specification", "d": ["Any process that modulates the frequency, rate or extent of salivary gland determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001007", "l": "negative regulation of cellulose biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellulose biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046465", "l": "dolichyl diphosphate metabolic process", "d": ["The chemical reactions and pathways involving dolichyl diphosphate, a diphosphorylated dolichol derivative. In eukaryotes, these function as carriers of mono- and oligosaccharide residues in the glycosylation of lipids and proteins within intracellular membranes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0006305", "l": "DNA alkylation", "d": ["The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051793", "l": "medium-chain fatty acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a fatty acid with an aliphatic tail of 6 to 12 carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035204", "l": "negative regulation of lamellocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904206", "l": "positive regulation of skeletal muscle hypertrophy", "d": ["Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048393", "l": "intermediate mesodermal cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into an intermediate mesoderm cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0021682", "l": "nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0052695", "l": "cellular glucuronidation", "d": ["The modification of an organic chemical by the conjugation of glucuronic acid. The substances resulting from glucuronidation are known as glucuronosides (or glucuronides) and are often much more water-soluble than the non-glucuronic acid-containing precursor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "51.381186176151004", "identifiers": [{"i": "GO:1901362", "l": "organic cyclic compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of organic cyclic compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0071773", "l": "cellular response to BMP stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042741", "l": "endogenous antibiotic catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated internally within the cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048352", "l": "paraxial mesoderm structural organization", "d": ["The process that contributes to the act of creating the structural organization of the paraxial mesoderm. This process pertains to the physical shaping of a rudimentary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035078", "l": "induction of programmed cell death by ecdysone", "d": ["Any process induced by the steroid hormone 20-hydroxyecdysone (ecdysone) that directly activates any of the steps required for programmed cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051030", "l": "snRNA transport", "d": ["The directed movement of snRNA, small nuclear ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032733", "l": "positive regulation of interleukin-10 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-10 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902692", "l": "regulation of neuroblast proliferation", "d": ["Any process that modulates the frequency, rate or extent of neuroblast proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070345", "l": "negative regulation of fat cell proliferation", "d": ["Any process that stops or decreases the rate or extent of fat cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098737", "l": "protein insertion into plasma membrane", "d": ["The process that results in the incorporation of a protein into a plasma membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0015884", "l": "folic acid transport", "d": ["The directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0016202", "l": "regulation of striated muscle tissue development", "d": ["Any process that modulates the frequency, rate or extent of striated muscle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072740", "l": "cellular response to anisomycin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018892", "l": "cyclohexylsulfamate metabolic process", "d": ["The chemical reactions and pathways involving cyclohexylsulfamate, also known as cyclamic acid. Sodium cyclohexylsulfamate (CHS-Na) was a widely used sweetening agent but was banned because of the suspicion of carcinogenicity and metabolic conversion to cyclohexylamine (CHA), a toxic substance. It is now used as a fungicide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901415", "l": "positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA", "d": ["Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010196", "l": "nonphotochemical quenching", "d": ["The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted as heat. This process helps maintain the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903040", "l": "exon-exon junction complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an exon-exon junction complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070141", "l": "response to UV-A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035037", "l": "sperm entry", "d": ["An endocytosis process that results in penetration of the egg shell through the micropyle (a specialized anterior opening in the vitelline envelope) and entry of the entire sperm, including the surrounding plasma membrane and the sperm tail, into the egg cytoplasm. This step in fertilization is seen in Drosophila, where a plasma membrane fusion event between the sperm and the egg does not occur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098912", "l": "membrane depolarization during atrial cardiac muscle cell action potential", "d": ["The process in which atrial cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044493", "l": "envenomation resulting in negative regulation of voltage-gated sodium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated sodium channel in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070832", "l": "phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline", "d": ["The phosphatidylcholine biosynthetic process that begins with three consecutive N-methylation steps that are carried out on phospho-bases, phosphoethanolamine, phospho-N-methylethanolamine, and phospho-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.128048714400073", "identifiers": [{"i": "GO:0009893", "l": "positive regulation of metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050937", "l": "regulation of iridophore differentiation", "d": ["Any process that modulates the frequency, rate or extent of iridophore differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045820", "l": "negative regulation of glycolytic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of glycolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0009850", "l": "auxin metabolic process", "d": ["The chemical reactions and pathways involving auxins, a group of plant hormones that regulate aspects of plant growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000565", "l": "negative regulation of CD8-positive, alpha-beta T cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061106", "l": "negative regulation of stomach neuroendocrine cell differentiation", "d": ["Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0045738", "l": "negative regulation of DNA repair", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009231", "l": "riboflavin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140421", "l": "endocytic heme import into cell", "d": ["The directed movement into cell of externally available heme by receptor-mediated endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003221", "l": "right ventricular cardiac muscle tissue morphogenesis", "d": ["The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034697", "l": "response to prostaglandin I", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901103", "l": "gramicidin S biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of gramicidin S."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0140919", "l": "thermomorphogenesis", "d": ["The suite of morphological and architectural changes in an organism induced by high ambient temperatures, below the heat-stress range."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0032527", "l": "protein exit from endoplasmic reticulum", "d": ["The directed movement of proteins from the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070134", "l": "positive regulation of mitochondrial translational initiation", "d": ["Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.881813014728969", "identifiers": [{"i": "GO:0006694", "l": "steroid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048704", "l": "embryonic skeletal system morphogenesis", "d": ["The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905441", "l": "response to chondroitin 4'-sulfate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.06379513530257", "identifiers": [{"i": "GO:0016068", "l": "type I hypersensitivity", "d": ["An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0099170", "l": "postsynaptic modulation of chemical synaptic transmission", "d": ["Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051594", "l": "detection of glucose", "d": ["The series of events in which a glucose stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905403", "l": "negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035893", "l": "negative regulation of platelet aggregation in another organism", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of platelet aggregation in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0022622", "l": "root system development", "d": ["The process whose specific outcome is the progression of the root system over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000442", "l": "positive regulation of toll-like receptor 15 signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of toll-like receptor 15 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006376", "l": "mRNA splice site recognition", "d": ["Selection of a splice site by components of the assembling spliceosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0030239", "l": "myofibril assembly", "d": ["Formation of myofibrils, the repeating units of striated muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901026", "l": "ripoptosome assembly involved in necroptotic process", "d": ["The aggregation, arrangement and bonding together of ripoptosome components leading to a necroptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900895", "l": "positive regulation of tridecane metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of tridecane metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010897", "l": "negative regulation of triglyceride catabolic process", "d": ["Any process that decreases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043683", "l": "type IV pilus assembly", "d": ["The assembly from its constituent parts of a type IV pilus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072579", "l": "glycine receptor clustering", "d": ["The receptor clustering process in which glycine receptors are localized to distinct domains in the cell membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046724", "l": "oxalic acid secretion", "d": ["The controlled release of oxalic acid, ethanedioic acid, by a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0015874", "l": "norepinephrine transport", "d": ["The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001080", "l": "nitrogen catabolite activation of transcription from RNA polymerase II promoter", "d": ["A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010134", "l": "sulfate assimilation via adenylyl sulfate reduction", "d": ["The pathway by which inorganic sulfate is activated, reduced and incorporated into sulfated compounds, where the activated sulfate, adenylyl-sulfate, is reduced to sulfite by the activity of adenylyl-sulfate reductase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010999", "l": "regulation of eIF2 alpha phosphorylation by heme", "d": ["Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a result of heme levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.774652552484312", "identifiers": [{"i": "GO:0009966", "l": "regulation of signal transduction", "d": ["Any process that modulates the frequency, rate or extent of signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006895", "l": "Golgi to endosome transport", "d": ["The directed movement of substances from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006207", "l": "'de novo' pyrimidine nucleobase biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015715", "l": "nucleotide-sulfate transport", "d": ["The directed movement of nucleotide sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046038", "l": "GMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of GMP, guanosine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002611", "l": "negative regulation of plasmacytoid dendritic cell antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0097709", "l": "connective tissue replacement", "d": ["The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904701", "l": "Wnt-Frizzled-LRP5/6 complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a Wnt-Frizzled-LRP5/6 complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0016073", "l": "snRNA metabolic process", "d": ["The chemical reactions and pathways involving snRNA, small nuclear RNA, any of various low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.861223582837674", "identifiers": [{"i": "GO:0048511", "l": "rhythmic process", "d": ["Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903945", "l": "positive regulation of hepatocyte apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061186", "l": "negative regulation of silent mating-type cassette heterochromatin formation", "d": ["Any process that decreases the frequency, rate, or extent of heterochromatin formation at silent mating-type cassette."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2000380", "l": "regulation of mesoderm development", "d": ["Any process that modulates the frequency, rate or extent of mesoderm development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.876036511014462", "identifiers": [{"i": "GO:0042593", "l": "glucose homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of glucose within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098790", "l": "ncRNA transcription associated with protein coding gene TSS/TES", "d": ["The transcription of non-coding RNA associated with transcriptional start and end sites of protein coding genes. This occurs at some low level for many protein coding genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061713", "l": "anterior neural tube closure", "d": ["The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042727", "l": "flavin-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021660", "l": "rhombomere 3 formation", "d": ["The process that gives rise to rhombomere 3. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061960", "l": "regulation of heme oxygenase activity", "d": ["Any process that modulates the frequency, or rate of heme oxygenase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0034656", "l": "nucleobase-containing small molecule catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019278", "l": "UDP-N-acetylgalactosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904570", "l": "negative regulation of selenocysteine incorporation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine incorporation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900088", "l": "regulation of inositol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of inositol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090212", "l": "negative regulation of establishment of blood-brain barrier", "d": ["Any process that decreases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019557", "l": "histidine catabolic process to glutamate and formate", "d": ["The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002395", "l": "immune response in nasopharyngeal-associated lymphoid tissue", "d": ["An immune response taking place in the nasopharyngeal-associated lymphoid tissue (NALT). NALT includes the tonsils and adenoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902966", "l": "positive regulation of protein localization to early endosome", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to early endosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903382", "l": "negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075010", "l": "regulation of germ tube formation", "d": ["Any process that modulates the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061886", "l": "negative regulation of mini excitatory postsynaptic potential", "d": ["Any process that decreases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000504", "l": "positive regulation of blood vessel remodeling", "d": ["Any process that activates or increases the frequency, rate or extent of blood vessel remodeling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:1990868", "l": "response to chemokine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0043374", "l": "CD8-positive, alpha-beta T cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0002921", "l": "negative regulation of humoral immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000486", "l": "cleavage between 5.8S rRNA and 2S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage between the 5.8S rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0010669", "l": "epithelial structure maintenance", "d": ["A tissue homeostatic process required for the maintenance of epithelial structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072287", "l": "metanephric distal tubule morphogenesis", "d": ["The process in which the anatomical structures of a metanephric distal tubule are generated and organized. The metanephric distal tubule is a metanephric nephron tubule that begins at the macula densa and extends to the metanephric connecting tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0032507", "l": "maintenance of protein location in cell", "d": ["Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002736", "l": "regulation of plasmacytoid dendritic cell cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002794", "l": "regulation of antimicrobial peptide secretion", "d": ["Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045898", "l": "regulation of RNA polymerase II transcription preinitiation complex assembly", "d": ["Any process that modulates the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019728", "l": "peptidyl-allysine oxidation to 2-aminoadipic acid", "d": ["The oxidation of allysine to 2-aminoadipic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009088", "l": "threonine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:1900911", "l": "regulation of olefin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of olefin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901165", "l": "positive regulation of trophoblast cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of trophoblast cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000567", "l": "regulation of memory T cell activation", "d": ["Any process that modulates the frequency, rate or extent of memory T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0033869", "l": "nucleoside bisphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140504", "l": "microlipophagy", "d": ["Microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion, such as during the transition to stationary phase or in response to nutrient limitation. Microlipophagy is mediated by the formation of sterol-enriched vacuolar microdomains at sites of engulfment. Initiation of microautophagy is defined as the point where liquid-ordered microdomains are formed at sites of engulfment, that requires S. cerevisiae Atg32p and Atg21p, as well as Niemann-Pick type C (NPC) sterol transporter proteins, Ncr1p and Npc2p. This is followed by redistribution of Atg14p from ER exit sites onto liquid-ordered vacuole membrane domains through interaction with stabilized AMP-activated protein kinase (AMPK), and together with Atg6p facilities docking and internalization of lipid droplets (LDs) at sites of invagination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000158", "l": "positive regulation of ubiquitin-specific protease activity", "d": ["Any process that activates or increases the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904132", "l": "positive regulation of convergent extension involved in neural plate elongation", "d": ["Any process that activates or increases the frequency, rate or extent of convergent extension involved in neural plate elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051122", "l": "hepoxilin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902868", "l": "positive regulation of retina development in camera-type eye", "d": ["Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0042304", "l": "regulation of fatty acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0032329", "l": "serine transport", "d": ["The directed movement of L-serine, 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072139", "l": "glomerular parietal epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900874", "l": "heptadec-1-ene metabolic process", "d": ["The chemical reactions and pathways involving heptadec-1-ene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099137", "l": "altruistic, chimeric, non-reproductive fruiting body development", "d": ["Development of a chimeric, non-reproductive fruiting body in which cells of all genotypes have an equal chance of becoming a spore cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019649", "l": "formaldehyde assimilation", "d": ["The pathways in which formaldehyde is processed and used as a carbon source for the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045945", "l": "positive regulation of transcription by RNA polymerase III", "d": ["Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase III."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019444", "l": "tryptophan catabolic process to catechol", "d": ["The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including catechol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002435", "l": "immune complex clearance by erythrocytes", "d": ["The process of immune complex clearance by erythrocytes. The process often starts with binding of complement receptor 1 (CR1) on the surface of erythrocytes to a complement coated immune complex. The complex bound to erythrocyte CR1 is then transported to the liver or spleen where it is presented to phagocytes. The process ends when the complex is removed from CR1, allowing the erythrocyte to return to general circulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900159", "l": "positive regulation of bone mineralization involved in bone maturation", "d": ["Any process that activates or increases the frequency, rate or extent of bone mineralization involved in bone maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0021872", "l": "forebrain generation of neurons", "d": ["The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010746", "l": "regulation of long-chain fatty acid import across plasma membrane", "d": ["Any process that modulates the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0050714", "l": "positive regulation of protein secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046152", "l": "ommochrome metabolic process", "d": ["The chemical reactions and pathways involving ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070151", "l": "mitochondrial histidyl-tRNA aminoacylation", "d": ["The process of coupling histidine to histidyl-tRNA in a mitochondrion, catalyzed by histidyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901703", "l": "protein localization involved in auxin polar transport", "d": ["Any protein localization that is involved in auxin polar transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033624", "l": "negative regulation of integrin activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of integrin activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905387", "l": "response to beta-carotene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0150021", "l": "apical dendrite morphogenesis", "d": ["The process in which the anatomical structures of an apical dendrite are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0035010", "l": "encapsulation of foreign target", "d": ["Events resulting in the formation of a multilayered cellular sheath surrounding an invader and thus preventing its development. This defense mechanism is often seen in insects in response to nematodes or parasitoids, which are too large to be phagocytosed by individual hemocytes. In some organisms the capsule is blackened due to melanization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0008062", "l": "eclosion rhythm", "d": ["The timing of the emergence of the adult fly from its pupal case, which usually occurs at dawn."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033089", "l": "positive regulation of T cell differentiation in thymus", "d": ["Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035200", "l": "leg disc anterior/posterior pattern formation", "d": ["The establishment, maintenance and elaboration of the anterior/posterior axis of the leg imaginal disc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.026697176653876", "identifiers": [{"i": "GO:0040007", "l": "growth", "d": ["The increase in size or mass of an entire organism, a part of an organism or a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097401", "l": "synaptic vesicle lumen acidification", "d": ["The acidification of the synaptic vesicle lumen via transport of protons into the vesicle. The resulting electrochemical gradient powers neurotransmitter loading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006602", "l": "creatinine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902269", "l": "positive regulation of polyamine transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of polyamine transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106434", "l": "retinal isomerization", "d": ["The reactions involved in isomerization of all trans to all cis retnal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0008212", "l": "mineralocorticoid metabolic process", "d": ["The chemical reactions and pathways involving mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Mineralocorticoids act primarily on water and electrolyte balance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019683", "l": "glyceraldehyde-3-phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glyceraldehyde-3-phosphate, an important intermediate in glycolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097113", "l": "AMPA glutamate receptor clustering", "d": ["The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060128", "l": "corticotropin hormone secreting cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036526", "l": "peptidyl-cysteine deglycation", "d": ["The removal of a sugar or dicarbonyl from a cysteine residue of a glycated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000982", "l": "positive regulation of inner ear receptor cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of inner ear receptor cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000898", "l": "regulation of glucomannan catabolic process", "d": ["Any process that modulates the frequency, rate or extent of glucomannan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072304", "l": "regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis", "d": ["Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905684", "l": "regulation of plasma membrane repair", "d": ["Any process that modulates the frequency, rate or extent of plasma membrane repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900837", "l": "regulation of fumigaclavine C biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of fumigaclavine C biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042793", "l": "plastid transcription", "d": ["The synthesis of RNA from a plastid DNA template, usually by a specific plastid RNA polymerase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0051453", "l": "regulation of intracellular pH", "d": ["Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0051512", "l": "positive regulation of unidimensional cell growth", "d": ["Any process that activates or increases the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021869", "l": "forebrain ventricular zone progenitor cell division", "d": ["The mitotic division of a basal progenitor giving rise to two neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1902657", "l": "protein localization to prospore membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within a prospore membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0046128", "l": "purine ribonucleoside metabolic process", "d": ["The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0001907", "l": "killing by symbiont of host cells", "d": ["Any process mediated by an organism that results in the death of cells in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045709", "l": "negative regulation of adult salivary gland boundary specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in an adult organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0003323", "l": "type B pancreatic cell development", "d": ["The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036196", "l": "zymosterol metabolic process", "d": ["The chemical reactions and pathways involving zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.151924274517057", "identifiers": [{"i": "GO:1901565", "l": "organonitrogen compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of organonitrogen compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000411", "l": "negative regulation of thymocyte migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0150065", "l": "regulation of deacetylase activity", "d": ["Any process that modulates the frequency, rate or extent of deacetylase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0005979", "l": "regulation of glycogen biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905304", "l": "regulation of cardiac myofibril assembly", "d": ["Any process that modulates the frequency, rate or extent of cardiac myofibril assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904303", "l": "positive regulation of maternal process involved in parturition", "d": ["Any process that activates or increases the frequency, rate or extent of maternal process involved in parturition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062191", "l": "galactoxylomannan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactoxylomannan. Galactoxylomannan is produced by a pathogenic fungus and causes paralysis in some animals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010637", "l": "negative regulation of mitochondrial fusion", "d": ["Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0023003", "l": "nuclear migration to the embryo sac center", "d": ["Migration of one of the four nuclei at each pole of the eight-nucleate embryo sac, to the center of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0051320", "l": "S phase", "d": ["The cell cycle phase, following G1, during which DNA synthesis takes place."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0098976", "l": "excitatory chemical synaptic transmission", "d": ["Synaptic transmission that results in an excitatory postsynaptic potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0006536", "l": "glutamate metabolic process", "d": ["The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0033338", "l": "medial fin development", "d": ["The process whose specific outcome is the progression of a medial fin over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0002718", "l": "regulation of cytokine production involved in immune response", "d": ["Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060197", "l": "cloacal septation", "d": ["The separation of the single opening of the digestive, urinary, and reproductive tracts, the cloaca, into multiple isolated openings during development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904351", "l": "negative regulation of protein catabolic process in the vacuole", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901871", "l": "ecgonone methyl ester catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ecgonone methyl ester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905170", "l": "negative regulation of protein localization to phagocytic vesicle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to phagocytic vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904415", "l": "regulation of xenophagy", "d": ["Any process that modulates the frequency, rate or extent of xenophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006398", "l": "mRNA 3'-end processing by stem-loop binding and cleavage", "d": ["Any mRNA 3'-end processing that involves the binding to and cleavage of a stem-loop structure. For example, histone mRNAs contain a highly conserved stem-loop sequence at the 3' end of the mRNA with a 6 base pairs (bp) stem and a 4-nt loop. The mRNA is cleaved between these two elements, after the fourth or fifth nucleotide, which is typically an adenosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0015755", "l": "fructose transmembrane transport", "d": ["The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990820", "l": "response to mitotic DNA integrity checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of mitotic DNA integrity checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060508", "l": "lung basal cell differentiation", "d": ["The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature basal cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. A basal cell is an epithelial stem cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1900103", "l": "positive regulation of endoplasmic reticulum unfolded protein response", "d": ["Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum unfolded protein response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "47.860992101236512", "identifiers": [{"i": "GO:0099536", "l": "synaptic signaling", "d": ["Cell-cell signaling to, from or within a synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045852", "l": "pH elevation", "d": ["Any process that increases the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044835", "l": "hydrogen generation via nitrogenase", "d": ["The chemical reactions and pathways resulting in the formation of H2 (dihydrogen) which involve a nitrogenase activity as one of the steps. This process is observed in cyanobacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048138", "l": "germ-line cyst encapsulation", "d": ["Formation of a single follicular epithelium around the germ-line derived cells of a cyst."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120222", "l": "regulation of blastocyst development", "d": ["Any process that modulates the frequency, rate or extent of blastocyst development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021540", "l": "corpus callosum morphogenesis", "d": ["The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0001569", "l": "branching involved in blood vessel morphogenesis", "d": ["The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060808", "l": "positive regulation of mesodermal to mesenchymal transition involved in gastrulation", "d": ["Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0043535", "l": "regulation of blood vessel endothelial cell migration", "d": ["Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0000288", "l": "nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "d": ["A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021739", "l": "mesencephalic trigeminal nucleus development", "d": ["The process whose specific outcome is the progression of the mesencephalic trigeminal nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042433", "l": "indole catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052102", "l": "positive regulation by symbiont of defense-related host calcium-dependent protein kinase pathway", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of the host calcium-dependent protein kinase pathway during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080022", "l": "primary root development", "d": ["The process whose specific outcome is the progression of the primary root over time, from its formation to the mature structure. The primary root develops directly from the embryonic radicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043974", "l": "histone H3-K27 acetylation", "d": ["The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 27 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:2001236", "l": "regulation of extrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061074", "l": "regulation of neural retina development", "d": ["Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150177", "l": "negative regulation of phosphatidylethanolamine metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylethanolamine metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070690", "l": "L-threonine catabolic process to acetyl-CoA", "d": ["The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) into glycine and acetaldehyde, with acetaldehyde being subsequently converted to acetyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.362525179576039", "identifiers": [{"i": "GO:0072522", "l": "purine-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031426", "l": "polycistronic mRNA processing", "d": ["The conversion of a primary mRNA transcript containing more than one complete protein-coding region into individual mature mRNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901326", "l": "response to tetracycline", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.936315447420142", "identifiers": [{"i": "GO:0006813", "l": "potassium ion transport", "d": ["The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903967", "l": "response to micafungin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000454", "l": "snoRNA guided rRNA pseudouridine synthesis", "d": ["The intramolecular conversion of uridine to pseudouridine in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of pseudouridylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903265", "l": "positive regulation of tumor necrosis factor-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000264", "l": "negative regulation of blood coagulation, extrinsic pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, extrinsic pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000912", "l": "regulation of galactoglucomannan catabolic process", "d": ["Any process that modulates the frequency, rate or extent of galactoglucomannan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0003025", "l": "regulation of systemic arterial blood pressure by baroreceptor feedback", "d": ["The neural regulation of blood pressure in which baroreceptors sense the amount of stretch occurring in vessels and respond to the input via central nervous system control."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904676", "l": "negative regulation of somatic stem cell division", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070986", "l": "left/right axis specification", "d": ["The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021639", "l": "trochlear nerve morphogenesis", "d": ["The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0021559", "l": "trigeminal nerve development", "d": ["The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000825", "l": "positive regulation of androgen receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of androgen receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902756", "l": "sulfurated eukaryotic molybdenum cofactor(2-) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sulfurated eukaryotic molybdenum cofactor(2-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060276", "l": "maintenance of stationary phase in response to toxin", "d": ["The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to a build-up of toxins in the environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902984", "l": "pre-replicative complex assembly involved in premeiotic DNA replication", "d": ["Any pre-replicative complex assembly involved in meiotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "51.791939768982942", "identifiers": [{"i": "GO:0006259", "l": "DNA metabolic process", "d": ["Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:0009251", "l": "glucan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0062021", "l": "mitotic cohesin dsDNA (leading strand) loading", "d": ["The protein localization to chromatin by which a cohesin ring complex is topologically linked to dsDNA (leading strand) as part of the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090281", "l": "negative regulation of calcium ion import", "d": ["Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900518", "l": "regulation of response to pullulan", "d": ["Any process that modulates the frequency, rate or extent of response to pullulan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055009", "l": "atrial cardiac muscle tissue morphogenesis", "d": ["The process in which the anatomical structure of cardiac atrium muscle is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045723", "l": "positive regulation of fatty acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002938", "l": "tRNA guanine ribose methylation", "d": ["The process whereby a guanosine residue in a tRNA is methylated on the 2'-hydroxyl group of the ribose moiety."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021743", "l": "hypoglossal nucleus development", "d": ["The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090449", "l": "phloem glucosinolate loading", "d": ["The process of loading glucosinolates into the sieve tube or companion cell of the phloem for long distance transport from source to sink."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.362525179576039", "identifiers": [{"i": "GO:0008211", "l": "glucocorticoid metabolic process", "d": ["The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0098703", "l": "calcium ion import across plasma membrane", "d": ["The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042932", "l": "chrysobactin transport", "d": ["The directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:0090130", "l": "tissue migration", "d": ["The process in which the population of cells that make up a tissue undergo directed movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018189", "l": "pyrroloquinoline quinone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070395", "l": "lipoteichoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900381", "l": "positive regulation of asperthecin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of asperthecin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900486", "l": "positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway", "d": ["Any process that activates or increases the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052391", "l": "induction by symbiont of defense-related host calcium ion flux", "d": ["The activation by an organism of a flux of calcium ions that occurs as part of the defense response of a host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0007007", "l": "inner mitochondrial membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial inner membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901123", "l": "bacitracin A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of bacitracin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0051984", "l": "positive regulation of chromosome segregation", "d": ["Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090014", "l": "leaflet formation", "d": ["The developmental process pertaining to the initial formation of a leaflet from unspecified parts. A leaflet is one of the ultimate segments of a compound leaf."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2000280", "l": "regulation of root development", "d": ["Any process that modulates the frequency, rate or extent of root development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0019396", "l": "gallate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061843", "l": "Sertoli cell barrier remodeling", "d": ["The tissue remodeling process by which the Sertoli cell barrier is temporarily disrupted and reorganized to accommodate the transit of preleptotene spermatocytes at stage VIII of the epithelial cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990545", "l": "mitochondrial thiamine pyrophosphate transmembrane transport", "d": ["The process in which thiamine pyrophosphate is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904942", "l": "regulation of cardiac ventricle formation", "d": ["Any process that modulates the frequency, rate or extent of cardiac ventricle formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071811", "l": "positive regulation of fever generation by positive regulation of prostaglandin biosynthesis", "d": ["Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0002645", "l": "positive regulation of tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018270", "l": "GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-alanine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of an alanyl-peptide bond in the carboxy-terminal region of a membrane-associated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900751", "l": "4-(trimethylammonio)butanoate transport", "d": ["The directed movement of a 4-(trimethylammonio)butanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0016076", "l": "snRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of snRNA, small nuclear RNA, low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045644", "l": "negative regulation of eosinophil differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of eosinophil differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002049", "l": "pyoverdine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061820", "l": "telomeric D-loop disassembly", "d": ["A telomere loop disassembly process that results in the disassembly of telomeric D-loops. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.966690184752494", "identifiers": [{"i": "GO:0014055", "l": "acetylcholine secretion, neurotransmission", "d": ["The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044642", "l": "envenomation resulting in modulation of complement activation, alternative pathway in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the alternative pathway in the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080136", "l": "priming of cellular response to stress", "d": ["The process that enables cells to respond in a more rapid and robust manner than nonprimed cells to much lower levels of a stimulus indicating the organism is under stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036302", "l": "atrioventricular canal development", "d": ["The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044474", "l": "envenomation resulting in negative regulation of voltage-gated calcium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated calcium channel in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048083", "l": "negative regulation of adult chitin-containing cuticle pigmentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0006152", "l": "purine nucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043157", "l": "response to cation stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901382", "l": "regulation of chorionic trophoblast cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0120033", "l": "negative regulation of plasma membrane bounded cell projection assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:2000377", "l": "regulation of reactive oxygen species metabolic process", "d": ["Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090201", "l": "negative regulation of release of cytochrome c from mitochondria", "d": ["Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.261443428098588", "identifiers": [{"i": "GO:0015721", "l": "bile acid and bile salt transport", "d": ["The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035367", "l": "positive regulation of thymine transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098669", "l": "superinfection exclusion", "d": ["The process by which a preexisting viral infection prevents a secondary infection with the same or a closely related virus. Typically some aspect of viral entry is inhibited, but post entry mechanisms have also been documented."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032621", "l": "interleukin-18 production", "d": ["The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061688", "l": "glycolytic process via Entner-Doudoroff Pathway", "d": ["A glycolytic process in which the glucose is catabolized to pyruvate by first entering the Entner-Doudoroff pathway to yield pyruvate and glyceraldehyde-3-phosphate. The glyceraldehyde-3-phosphate is subsequently converted to pyruvate by the core glycolytic enzymes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902367", "l": "negative regulation of Notch signaling pathway involved in somitogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Notch signaling pathway involved in somitogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048298", "l": "positive regulation of isotype switching to IgA isotypes", "d": ["Any process that activates or increases the frequency, rate or extent of isotype switching to IgA isotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002926", "l": "tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation", "d": ["The process whereby a wobble base uridine residue in a tRNA is modified to 5-methoxycarbonylmethyl-2-thiouridine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034106", "l": "regulation of erythrocyte clearance", "d": ["Any process that modulates the frequency, rate, or extent of erythrocyte clearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006781", "l": "succinyl-CoA pathway", "d": ["The chemical reactions that utilize succinyl-CoA in the synthesis of protoporphyrin IX."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002634", "l": "regulation of germinal center formation", "d": ["Any process that modulates the frequency, rate, or extent of germinal center formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0036376", "l": "sodium ion export across plasma membrane", "d": ["The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010135", "l": "ureide metabolic process", "d": ["The chemical reactions and pathways involving ureide, allantoin and allantoate, which are the organic forms of nitrogen in nitrogen fixing and transporting plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0090220", "l": "chromosome localization to nuclear envelope involved in homologous chromosome segregation", "d": ["The directed movement of a chromosome to the nuclear envelope that contributes to homologous chromosome segregation and precedes synapsis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120049", "l": "snRNA (adenine-N6)-methylation", "d": ["The posttranscriptional N6-methylation of an adenine residue in an snRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901233", "l": "negative regulation of convergent extension involved in axis elongation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in axis elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002501", "l": "peptide antigen assembly with MHC protein complex", "d": ["The binding of a peptide to the antigen binding groove of an MHC protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0002585", "l": "positive regulation of antigen processing and presentation of peptide antigen", "d": ["Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043568", "l": "positive regulation of insulin-like growth factor receptor signaling pathway", "d": ["Any process that increases the frequency, rate or extent of insulin-like growth factor receptor signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903013", "l": "response to differentiation-inducing factor 1", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0098902", "l": "regulation of membrane depolarization during action potential", "d": ["Any process that modulates the rate, frequency or extent of membrane depolarization during an action potential. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085044", "l": "disassembly by symbiont of host cuticle", "d": ["The process in which a symbiont organism effects a breakdown of the host organism cuticle. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.062578713639986", "identifiers": [{"i": "GO:0043067", "l": "regulation of programmed cell death", "d": ["Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060424", "l": "lung field specification", "d": ["The process that results in the delineation of a specific region of the foregut into the area in which the lung will develop."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003039", "l": "detection of reduced oxygen by carotid body chemoreceptor signaling", "d": ["The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in a carotid body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990773", "l": "matrix metallopeptidase secretion", "d": ["The regulated release of matrix metallopeptidases, a family of zinc-dependent endopeptidases that can degrade extracellular matrix proteins and process other types of proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046740", "l": "transport of virus in host, cell to cell", "d": ["The transport of a virus between adjacent cells in a multicellular organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061365", "l": "positive regulation of triglyceride lipase activity", "d": ["Any process that increases the activity of triglyceride lipase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006562", "l": "proline catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048842", "l": "positive regulation of axon extension involved in axon guidance", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of axon extension involved in axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900548", "l": "heme B catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018295", "l": "protein-FAD linkage via 3'-(8alpha-FAD)-L-histidine", "d": ["The formation of a protein-FAD linkage via 3'-(8-alpha-FAD)-L-histidine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097680", "l": "double-strand break repair via classical nonhomologous end joining", "d": ["An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination, including the KU70/80 heterodimer (KU), XRCC4, ligase IV, and DNA-PKcs in mammals. It does not produce translocations (as opposed to the alternative nonhomologous end joining)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904514", "l": "positive regulation of initiation of premeiotic DNA replication", "d": ["Any process that activates or increases the frequency, rate or extent of initiation of premeiotic DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000464", "l": "endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage within Internal Transcribed Spacer 1 (ITS1) upstream of the 5.8S rRNA derived from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, this endonucleolytic cleavage within ITS1 initiates the maturation of the LSU and the 5.8S rRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904879", "l": "positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0048167", "l": "regulation of synaptic plasticity", "d": ["A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060416", "l": "response to growth hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018864", "l": "acetylene metabolic process", "d": ["The chemical reactions and pathways involving acetylene, formula CH2CH2, the simplest of the alkynes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.892466024748572", "identifiers": [{"i": "GO:0061545", "l": "tyramine secretion", "d": ["The regulated release of a tyramine by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071606", "l": "chemokine (C-C motif) ligand 4 production", "d": ["The appearance of chemokine (C-C motif) ligand 4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033656", "l": "modification by symbiont of host chloroplast", "d": ["The process in which an organism effects a change in the structure or function of host cell chloroplasts. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014036", "l": "neural crest cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072066", "l": "prebend segment development", "d": ["The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046828", "l": "regulation of RNA import into nucleus", "d": ["Any process that modulates the frequency, rate or extent of movement of RNA from the cytoplasm to the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0010073", "l": "meristem maintenance", "d": ["Any process involved in maintaining the identity, size and shape of a meristem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046604", "l": "positive regulation of mitotic centrosome separation", "d": ["Any process that activates or increases the frequency, rate or extent of centrosome separation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0046823", "l": "negative regulation of nucleocytoplasmic transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900637", "l": "regulation of asperfuranone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of asperfuranone biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0150019", "l": "basal dendrite morphogenesis", "d": ["The process in which the anatomical structures of a basal dendrite are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061095", "l": "positive regulation of turning behavior involved in mating", "d": ["Any process that increases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001157", "l": "negative regulation of proline catabolic process to glutamate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of proline catabolic process to glutamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0016111", "l": "polyterpenoid metabolic process", "d": ["The chemical reactions and pathways involving polyterpenoid compounds, terpenoids with more than eight isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904783", "l": "positive regulation of NMDA glutamate receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of NMDA glutamate receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0014901", "l": "satellite cell activation involved in skeletal muscle regeneration", "d": ["The process that initiates skeletal muscle satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006727", "l": "ommochrome biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009720", "l": "detection of hormone stimulus", "d": ["The series of events in which a hormone stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0010092", "l": "specification of animal organ identity", "d": ["The regionalization process in which the identity of an animal organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010643", "l": "cell communication by chemical coupling", "d": ["The process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.82717435204831", "identifiers": [{"i": "GO:0050793", "l": "regulation of developmental process", "d": ["Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042998", "l": "positive regulation of Golgi to plasma membrane protein transport", "d": ["Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002746", "l": "antigen processing and presentation following pinocytosis", "d": ["Antigen processing and presentation which is initiated by uptake of antigen via pinocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0052422", "l": "modulation by host of symbiont catalytic activity", "d": ["The process in which a host organism effects a change in the enzyme activity of its symbiont organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046065", "l": "dCTP metabolic process", "d": ["The chemical reactions and pathways involving dCTP, deoxycytidine triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902941", "l": "regulation of voltage-gated chloride channel activity", "d": ["Any process that modulates the frequency, rate or extent of voltage-gated chloride channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019306", "l": "GDP-D-rhamnose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009901", "l": "anther dehiscence", "d": ["The dehiscence of an anther to release the pollen grains contained within it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0022608", "l": "multicellular organism adhesion", "d": ["The attachment of a multicellular organism to a substrate or other organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.415093686714229", "identifiers": [{"i": "GO:0060759", "l": "regulation of response to cytokine stimulus", "d": ["Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "45.437429825317274", "identifiers": [{"i": "GO:0050906", "l": "detection of stimulus involved in sensory perception", "d": ["The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0031342", "l": "negative regulation of cell killing", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902026", "l": "regulation of cartilage condensation", "d": ["Any process that modulates the frequency, rate or extent of cartilage condensation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010799", "l": "regulation of peptidyl-threonine phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002809", "l": "negative regulation of antibacterial peptide biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902490", "l": "regulation of sperm capacitation", "d": ["Any process that modulates the frequency, rate or extent of sperm capacitation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061298", "l": "retina vasculature development in camera-type eye", "d": ["The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071584", "l": "negative regulation of zinc ion transmembrane import", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of zinc ion import."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060261", "l": "positive regulation of transcription initiation by RNA polymerase II", "d": ["Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120175", "l": "regulation of torso signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the torso signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009208", "l": "pyrimidine ribonucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070941", "l": "eisosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an eisosome, a cell part that is composed of the eisosome membrane and eisosome filaments. The eisosome membrane, also called the MCC domain, is a furrow-like plasma membrane sub-domain with associated integral transmembrane proteins. The eisosome filaments form a scaffolding lattice on the cytoplasmic face of the membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0042212", "l": "cresol metabolic process", "d": ["The chemical reactions and pathways involving cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.550707717106313", "identifiers": [{"i": "GO:0006260", "l": "DNA replication", "d": ["The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051344", "l": "negative regulation of cyclic-nucleotide phosphodiesterase activity", "d": ["Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904791", "l": "negative regulation of shelterin complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of shelterin complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140744", "l": "negative regulation of lncRNA transcription", "d": ["Any process that decreases the frequency, rate or extent of the synthesis of a lncRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0022609", "l": "multicellular organism adhesion to substrate", "d": ["The attachment of a multicellular organism to a surface or material."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035542", "l": "regulation of SNARE complex assembly", "d": ["Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043305", "l": "negative regulation of mast cell degranulation", "d": ["Any process that stops, prevents, or reduces the rate of mast cell degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060385", "l": "axonogenesis involved in innervation", "d": ["The neurite development process that generates a long process of a neuron, as it invades a target tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903624", "l": "regulation of DNA catabolic process", "d": ["Any process that modulates the frequency, rate or extent of DNA catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046719", "l": "regulation by virus of viral protein levels in host cell", "d": ["Any virus-mediated process that modulates the levels of viral proteins in a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140447", "l": "cytokine precursor processing", "d": ["The cleavage of a peptide bond in a precursor form of a cytokine, resulting in the mature (active) form of the cytokine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000797", "l": "regulation of amniotic stem cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of amniotic stem cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0070654", "l": "sensory epithelium regeneration", "d": ["The regrowth of a sensory epithelium following its loss or destruction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0006004", "l": "fucose metabolic process", "d": ["The chemical reactions and pathways involving fucose, or 6-deoxygalactose, which has two enantiomers, D-fucose and L-fucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.033057138195133", "identifiers": [{"i": "GO:0001525", "l": "angiogenesis", "d": ["Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021980", "l": "subpallium cell migration", "d": ["The orderly movement of cells from one site to another in the subpallium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009175", "l": "pyrimidine ribonucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0110009", "l": "formin-nucleated actin cable organization", "d": ["A process that results in the assembly, arrangement of constituent parts, or disassembly of a formin-nucleated actin cable."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006223", "l": "uracil salvage", "d": ["Any process that generates uracil, 2,4-dioxopyrimidine, from derivatives of it without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060302", "l": "negative regulation of cytokine activity", "d": ["Any process that decreases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007107", "l": "membrane addition at site of cytokinesis", "d": ["Any process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031271", "l": "lateral pseudopodium assembly", "d": ["The extension of a pseudopodium from the lateral area of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.330711238774875", "identifiers": [{"i": "GO:0150063", "l": "visual system development", "d": ["The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.780700721499244", "identifiers": [{"i": "GO:0015748", "l": "organophosphate ester transport", "d": ["The directed movement of organophosphate esters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organophosphate esters are small organic molecules containing phosphate ester bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.824513090543306", "identifiers": [{"i": "GO:0006575", "l": "cellular modified amino acid metabolic process", "d": ["The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048161", "l": "double layer follicle stage", "d": ["The stage in oogenesis when a double layer of distinct follicle cells surrounds the oocyte. An example of this process is found in Mus musculus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043322", "l": "negative regulation of natural killer cell degranulation", "d": ["Any process that stops, prevents, or reduces the rate of natural killer cell degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0007614", "l": "short-term memory", "d": ["The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0052089", "l": "modulation by symbiont of host salicylic acid-mediated defense response", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903234", "l": "negative regulation of calcium ion-dependent exocytosis of neurotransmitter", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033499", "l": "galactose catabolic process via UDP-galactose", "d": ["The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0048266", "l": "behavioral response to pain", "d": ["Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000322", "l": "regulation of glucocorticoid receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of glucocorticoid receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900678", "l": "regulation of ferricrocin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of ferricrocin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070197", "l": "meiotic attachment of telomere to nuclear envelope", "d": ["The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042194", "l": "quinate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of quinate, the anion of quinic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034255", "l": "regulation of urea metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving urea."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000700", "l": "positive regulation of cardiac muscle cell myoblast differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046427", "l": "positive regulation of receptor signaling pathway via JAK-STAT", "d": ["Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034446", "l": "substrate adhesion-dependent cell spreading", "d": ["The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0070948", "l": "regulation of neutrophil mediated cytotoxicity", "d": ["Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140881", "l": "positive regulation terrein biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of the fungal metabolite terrein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002827", "l": "positive regulation of T-helper 1 type immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035679", "l": "anterior lateral line neuromast hair cell morphogenesis", "d": ["The change in form (cell shape and size) that occurs when an anterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903944", "l": "negative regulation of hepatocyte apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0071825", "l": "protein-lipid complex organization", "d": ["Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0071707", "l": "immunoglobulin heavy chain V-D-J recombination", "d": ["The process in which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0019747", "l": "regulation of isoprenoid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.853579598310013", "identifiers": [{"i": "GO:0014033", "l": "neural crest cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002191", "l": "cap-dependent translational initiation", "d": ["The process where the cap structure, composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins, located at the 5' end of an mRNA molecule, which serves as a molecular tag that marks the spot where the 40S ribosomal subunit, is recruited and will then scan in a 5' to 3' direction until an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019617", "l": "protocatechuate catabolic process, meta-cleavage", "d": ["The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield oxaloacetate and pyruvate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098726", "l": "symmetric division of skeletal muscle satellite stem cell", "d": ["The symmetric division of a skeletal muscle satellite stem cell, resulting in two skeletal muscle satellite stem cells. This process is involved in amplification of the pool of these cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.959712637402532", "identifiers": [{"i": "GO:0010638", "l": "positive regulation of organelle organization", "d": ["Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010408", "l": "fasciclin-like arabinogalactan protein metabolic process", "d": ["The chemical reactions and pathways involving the cell wall arabinogalactan II glycoprotein variant which contains both an arabinogalactan protein (AGP) motif and a fasciclin domain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0072282", "l": "metanephric nephron tubule morphogenesis", "d": ["The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0042100", "l": "B cell proliferation", "d": ["The expansion of a B cell population by cell division. Follows B cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0034698", "l": "response to gonadotropin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904295", "l": "regulation of osmolarity-sensing cation channel activity", "d": ["Any process that modulates the frequency, rate or extent of osmolarity-sensing cation channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0016143", "l": "S-glycoside metabolic process", "d": ["The chemical reactions and pathways involving S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045470", "l": "R8 cell-mediated photoreceptor organization", "d": ["The regionalization process that coordinates the recruitment and organization of other non-R8 photoreceptors by the R8 photoreceptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061477", "l": "response to aromatase inhibitor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aromatase inhibitor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904239", "l": "regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly", "d": ["Any process that modulates the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046548", "l": "retinal rod cell development", "d": ["Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000760", "l": "negative regulation of N-terminal peptidyl-lysine acetylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-lysine acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900919", "l": "positive regulation of octadecene metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of octadecene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060567", "l": "negative regulation of termination of DNA-templated transcription", "d": ["Any process that decreases the rate, frequency or extent of DNA-dependent transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0014864", "l": "detection of muscle activity", "d": ["The series of events in which a muscle activity stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061524", "l": "central canal development", "d": ["The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0021679", "l": "cerebellar molecular layer development", "d": ["The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060945", "l": "cardiac neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002617", "l": "negative regulation of macrophage antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0051383", "l": "kinetochore organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001271", "l": "negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032790", "l": "ribosome disassembly", "d": ["The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900715", "l": "positive regulation of violaceol I biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of violaceol I biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905832", "l": "positive regulation of spindle assembly", "d": ["Any process that activates or increases the frequency, rate or extent of spindle assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.99338298237501", "identifiers": [{"i": "GO:0046700", "l": "heterocycle catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018141", "l": "peptide cross-linking via L-lysine thiazolecarboxylic acid", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl lysine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0002418", "l": "immune response to tumor cell", "d": ["An immune system process that functions in the response of an organism to a tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901687", "l": "glutathione derivative biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glutathione derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901747", "l": "prephenate(2-) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of prephenate(2-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000997", "l": "regulation of cellulose catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellulose catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060694", "l": "regulation of cholesterol transporter activity", "d": ["Any process that modulates the rate, frequency, or extent of cholesterol transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002318", "l": "myeloid progenitor cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001717", "l": "conversion of seryl-tRNAsec to selenocys-tRNAsec", "d": ["The modification process that results in the conversion of serine, carried by a specialized tRNA(ser) (which can read a UGA anticodon), to selenocysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0097091", "l": "synaptic vesicle clustering", "d": ["The process that results in grouping synaptic vesicles in presynaptic structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0045144", "l": "meiotic sister chromatid segregation", "d": ["The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000192", "l": "negative regulation of fatty acid transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0052647", "l": "pentitol phosphate metabolic process", "d": ["The chemical reactions and pathways involving pentitol phosphates, any phosphorylated alditol with a chain of five carbon atoms in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0032261", "l": "purine nucleotide salvage", "d": ["Any process which produces a purine nucleotide from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901508", "l": "positive regulation of acylglycerol transport", "d": ["Any process that activates or increases the frequency, rate or extent of acylglycerol transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075199", "l": "positive regulation of symbiont haustorium neck formation for entry into host", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001024", "l": "negative regulation of response to drug", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to drug."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903917", "l": "positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043538", "l": "regulation of actin phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of the transfer of one or more phosphate groups to an actin molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:2000200", "l": "regulation of ribosomal subunit export from nucleus", "d": ["Any process that modulates the frequency, rate or extent of ribosomal subunit export from nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120188", "l": "regulation of bile acid secretion", "d": ["Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046012", "l": "positive regulation of oskar mRNA translation", "d": ["Any process that activates or increases the frequency, rate or extent of oskar mRNA translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015685", "l": "ferric-enterobactin import into cell", "d": ["A process in which ferric-enterobactin, the iron-bound form of the siderophore enterobactin, is transported into the cell by specific cell surface receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.879406879579491", "identifiers": [{"i": "GO:0006096", "l": "glycolytic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000447", "l": "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045146", "l": "initiation of acetate catabolic process by acetate", "d": ["The activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019553", "l": "glutamate catabolic process via L-citramalate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-citramalate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070367", "l": "negative regulation of hepatocyte differentiation", "d": ["Any process that stops or decreases the rate or extent of hepatocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0002465", "l": "peripheral tolerance induction", "d": ["Tolerance induction in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046153", "l": "ommochrome catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036331", "l": "avascular cornea development in camera-type eye", "d": ["The progression of an avascular cornea over time, from its formation to the mature structure. Corneal avascularity (the absence of blood vessels in the cornea) is required for optical clarity and optimal vision. Avascular corneas are present in most animals, except Manatees."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.134834654920184", "identifiers": [{"i": "GO:0009798", "l": "axis specification", "d": ["The establishment, maintenance and elaboration of a pattern along a line or around a point."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045632", "l": "negative regulation of mechanoreceptor differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mechanoreceptor differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0046364", "l": "monosaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905444", "l": "negative regulation of clathrin coat assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of clathrin coat assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044081", "l": "disruption of host nitric oxide-mediated signaling", "d": ["Any process in which a symbiont organism interferes with nitric oxide mediated signal transduction in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042791", "l": "5S class rRNA transcription by RNA polymerase III", "d": ["The synthesis of 5S ribosomal RNA (rRNA), or an equivalent rRNA, from a DNA template by RNA polymerase III (Pol III), originating at a type 1 RNA polymerase III promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.415093686714229", "identifiers": [{"i": "GO:0006397", "l": "mRNA processing", "d": ["Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060210", "l": "metestrus", "d": ["The estrous cycle phase in which there is subsiding follicular function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000410", "l": "carbon catabolite repression of transcription by galactose", "d": ["A transcription regulation process in which the presence of galactose that leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901140", "l": "p-coumaryl alcohol transport", "d": ["The directed movement of a p-coumaryl alcohol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:2000849", "l": "regulation of glucocorticoid secretion", "d": ["Any process that modulates the frequency, rate or extent of glucocorticoid secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.019064301362803", "identifiers": [{"i": "GO:0050953", "l": "sensory perception of light stimulus", "d": ["The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010728", "l": "regulation of hydrogen peroxide biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.990900157612501", "identifiers": [{"i": "GO:0031032", "l": "actomyosin structure organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090389", "l": "phagosome-lysosome fusion involved in apoptotic cell clearance", "d": ["The creation of a phagolysosome from a phagosome and a lysosome as a part of apoptotic cell clearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046187", "l": "acetaldehyde catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902841", "l": "regulation of netrin-activated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of netrin-activated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0001702", "l": "gastrulation with mouth forming second", "d": ["A gastrulation process in which the initial invagination becomes the anus and the mouth forms second."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903545", "l": "cellular response to butyrate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006056", "l": "mannoprotein metabolic process", "d": ["The chemical reactions and pathways involving a mannoprotein, a protein that contains covalently bound mannose residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.809526531696484", "identifiers": [{"i": "GO:0051130", "l": "positive regulation of cellular component organization", "d": ["Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905289", "l": "regulation of CAMKK-AMPK signaling cascade", "d": ["Any process that modulates the frequency, rate or extent of CAMKK-AMPK signaling cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110163", "l": "negative regulation of mitotic spindle elongation (spindle phase three)", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002614", "l": "negative regulation of monocyte antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060661", "l": "submandibular salivary gland formation", "d": ["The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902950", "l": "regulation of dendritic spine maintenance", "d": ["Any process that modulates the frequency, rate or extent of dendritic spine maintenance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015913", "l": "short-chain fatty acid transmembrane transport", "d": ["The directed movement of short-chain fatty acids into a cell or organelle. A short-chain fatty acid is a fatty acid with an aliphatic tail of less than 6 carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009442", "l": "allantoin assimilation pathway", "d": ["The pathways by which allantoin is processed and converted to ureidoglycolate, and then into metabolically useful substrates. E. coli are able to utilize allantoin as a sole nitrogen source under anaerobic conditions by converting it to ureidoglycolate; this may be further metabolized to produce glyoxylate and thence 3-phosphoglycerate, or alternatively oxidized to oxolureate, which can converted into oxamate and carbamoylphosphate. This may then be further metabolized to CO2, NH4+ and ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048338", "l": "mesoderm structural organization", "d": ["The process that contributes to the act of creating the structural organization of the mesoderm. This process pertains to the physical shaping of a rudimentary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034461", "l": "uropod retraction", "d": ["The process in which a uropod detaches from the cell substrate and retracts the rear of a migrating cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006171", "l": "cAMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061377", "l": "mammary gland lobule development", "d": ["The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032570", "l": "response to progesterone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075249", "l": "positive regulation of aeciospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905420", "l": "vascular associated smooth muscle cell differentiation involved in phenotypic switching", "d": ["Any vascular smooth muscle cell differentiation that is involved in phenotypic switching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036451", "l": "cap mRNA methylation", "d": ["Methylation of the 2'-O-ribose of the first or second transcribed nucleotide of a 5'-capped mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900697", "l": "positive regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071391", "l": "cellular response to estrogen stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046867", "l": "carotenoid transport", "d": ["The directed movement of carotenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carotenoids are tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904641", "l": "response to dinitrophenol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010113", "l": "negative regulation of systemic acquired resistance", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of systemic acquired resistance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052001", "l": "adhesion to host cell via type IV pili", "d": ["Attachment of bacterial clusters to the surface of the host in a type IV pili dependent manner. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0052701", "l": "cellular modified histidine metabolic process", "d": ["The chemical reactions and pathways involving compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0009713", "l": "catechol-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900624", "l": "negative regulation of monocyte aggregation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of monocyte aggregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072270", "l": "metanephric short nephron development", "d": ["The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060370", "l": "susceptibility to T cell mediated cytotoxicity", "d": ["The process of causing a cell to become susceptible to T cell mediated cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.330199557084356", "identifiers": [{"i": "GO:0034308", "l": "primary alcohol metabolic process", "d": ["The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002531", "l": "regulation of heart contraction involved in acute-phase response", "d": ["Any process that modulates the frequency, rate or extent of heart contraction that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905461", "l": "positive regulation of vascular associated smooth muscle cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0160032", "l": "Toll receptor ligand protein activation cascade", "d": ["A protein activation cascade that generates the active Toll receptor ligand and consists of the cascade of enzymatic reactions initiated by extracellular recognition factors, leading to the cleavage of the inactive form of spatzle family of ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905556", "l": "ciliary vesicle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a ciliary vesicle. Multiple smaller vesicles dock to the transitional fibers on a mature basal body and then fuse together to form a larger single vesicle. This then fuses with the plasma membrane and forms the ciliary membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021709", "l": "cerebellar basket cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar basket cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar basket cell fate. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.879861732516552", "identifiers": [{"i": "GO:0009914", "l": "hormone transport", "d": ["The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901224", "l": "positive regulation of NIK/NF-kappaB signaling", "d": ["Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902898", "l": "fatty acid methyl ester metabolic process", "d": ["The chemical reactions and pathways involving fatty acid methyl ester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036511", "l": "trimming of first mannose on A branch", "d": ["The removal of the first alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072112", "l": "podocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043475", "l": "pigment metabolic process involved in pigment accumulation", "d": ["The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, as part of the accumulation of pigment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110019", "l": "IRES-dependent translational initiation of circular RNA", "d": ["The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate circular mRNA translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010051", "l": "xylem and phloem pattern formation", "d": ["The regionalization process that gives rise to the patterning of the conducting tissues. An example of this process is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051026", "l": "chiasma assembly", "d": ["The cell cycle process in which a connection between chromatids assembles, indicating where an exchange of homologous segments has taken place by the crossing-over of non-sister chromatids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.096227290700369", "identifiers": [{"i": "GO:0098754", "l": "detoxification", "d": ["Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052021", "l": "modulation by symbiont of ethylene levels in host", "d": ["The alteration by an organism of the levels of ethylene in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034132", "l": "negative regulation of toll-like receptor 1 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 1 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060458", "l": "right lung development", "d": ["The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002923", "l": "regulation of humoral immune response mediated by circulating immunoglobulin", "d": ["Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015762", "l": "rhamnose transmembrane transport", "d": ["The process in which rhamnose is transported across a lipid bilayer, from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021597", "l": "central nervous system structural organization", "d": ["The process that contributes to the act of creating the structural organization of the central nervous system structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098530", "l": "positive regulation of strand invasion", "d": ["Any process that increases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904071", "l": "presynaptic active zone assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a presynaptic active zone. The presynaptic active zone is a specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0009219", "l": "pyrimidine deoxyribonucleotide metabolic process", "d": ["The chemical reactions and pathways involving a pyrimidine deoxynucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031158", "l": "negative regulation of aggregate size involved in sorocarp development", "d": ["Any process that decreases the size of the aggregate formed during sorocarp formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034052", "l": "positive regulation of plant-type hypersensitive response", "d": ["Any process that activates or increases the frequency, rate or extent of the hypersensitive response in a plant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901533", "l": "negative regulation of hematopoietic progenitor cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901831", "l": "all-trans-neoxanthin metabolic process", "d": ["The chemical reactions and pathways involving all-trans-neoxanthin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032622", "l": "interleukin-19 production", "d": ["The appearance of interleukin-19 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045461", "l": "sterigmatocystin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900930", "l": "negative regulation of L-tyrosine import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-tyrosine import into the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042122", "l": "alginic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:1904776", "l": "regulation of protein localization to cell cortex", "d": ["Any process that modulates the frequency, rate or extent of protein localization to cell cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0000921", "l": "septin ring assembly", "d": ["The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010262", "l": "somatic embryogenesis", "d": ["Initiation of a somatic embryo-an embryo arising from previously differentiated somatic cells, rather than from fused haploid gametes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0016578", "l": "histone deubiquitination", "d": ["The modification of histones by removal of ubiquitin groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061268", "l": "mesonephric interstitial fibroblast fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial fibroblast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002479", "l": "antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071720", "l": "sodium-independent prostaglandin transport", "d": ["The directed, sodium-independent, movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061979", "l": "femoral head articular cartilage development", "d": ["The process whose specific outcome is the progression of femoral head articular cartilage over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009990", "l": "contact guidance", "d": ["Cell recognition involving the deposition of specific pathways in the extracellular matrix that guide migrating cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0071622", "l": "regulation of granulocyte chemotaxis", "d": ["Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015778", "l": "hexuronide transmembrane transport", "d": ["The directed movement of hexuronide across a membrane. Hexuronides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of a hexuronate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055060", "l": "asymmetric neuroblast division resulting in ganglion mother cell formation", "d": ["Any process resulting in the physical partitioning and separation of a neuroblast into a neuroblast and a ganglion mother cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071045", "l": "nuclear histone mRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA) within the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035279", "l": "miRNA-mediated gene silencing by mRNA destabilization", "d": ["An RNA interference pathway in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0006907", "l": "pinocytosis", "d": ["An endocytosis process that results in the uptake of liquid material by cells from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, called pinosomes, formed by invagination of the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072238", "l": "metanephric long nephron development", "d": ["The process whose specific outcome is the progression of a metanephric long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046454", "l": "dimethylsilanediol metabolic process", "d": ["The chemical reactions and pathways involving dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060830", "l": "ciliary receptor clustering involved in smoothened signaling pathway", "d": ["Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051620", "l": "norepinephrine uptake", "d": ["The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042400", "l": "ectoine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901012", "l": "(S)-reticuline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (S)-reticuline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010625", "l": "positive regulation of Schwann cell proliferation", "d": ["Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990966", "l": "ATP generation from poly-ADP-D-ribose", "d": ["The process of generating ATP in the nucleus from poly-ADP-D-ribose. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090200", "l": "positive regulation of release of cytochrome c from mitochondria", "d": ["Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060814", "l": "posterior mRNA localization involved in anterior/posterior axis specification", "d": ["Any process in which a mRNA is transported to and maintained in the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032910", "l": "regulation of transforming growth factor beta3 production", "d": ["Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000413", "l": "protein peptidyl-prolyl isomerization", "d": ["The modification of a protein by cis-trans isomerization of a proline residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042874", "l": "D-glucuronate transmembrane transport", "d": ["The process in which D-glucuronate, the D-enantiomer of glucuronate, is transported across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000891", "l": "cellobiose metabolic process", "d": ["The chemical reactions and pathways involving a cellobiose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003252", "l": "negative regulation of cell proliferation involved in heart valve morphogenesis", "d": ["Any process that decreases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032485", "l": "regulation of Ral protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of Ral protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140591", "l": "nuclear envelope budding", "d": ["The process by which large macromolecular complexes are budded through the inner nuclear membrane, into the perinuclear space, thus acquiring a membrane envelope. The enveloped particle fuses with the outer nuclear membrane and is released into the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001922", "l": "B-1 B cell homeostasis", "d": ["The process of regulating the proliferation and elimination of B cells of the B-1 subset such that the total number of B-1 B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060764", "l": "cell-cell signaling involved in mammary gland development", "d": ["Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032061", "l": "negative regulation of translation in response to osmotic stress", "d": ["Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901969", "l": "positive regulation of polynucleotide 3'-phosphatase activity", "d": ["Any process that activates or increases the frequency, rate or extent of polynucleotide 3'-phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904652", "l": "protein localization to cell division site involved in cell separation after cytokinesis", "d": ["Any protein localization to cell division site that is involved in cell separation after cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048908", "l": "anterior lateral line ganglion neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron of the anterior lateral line ganglion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900871", "l": "chloroplast mRNA modification", "d": ["The covalent alteration within the chloroplast of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070207", "l": "protein homotrimerization", "d": ["The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046425", "l": "regulation of receptor signaling pathway via JAK-STAT", "d": ["Any process that modulates the frequency, rate or extent of receptor signaling via JAK-STAT."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046086", "l": "adenosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0140112", "l": "extracellular vesicle biogenesis", "d": ["The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045459", "l": "iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide", "d": ["The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035995", "l": "detection of muscle stretch", "d": ["The series of events by which a muscle stretch stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904661", "l": "negative regulation of sensory perception of bitter taste", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of bitter taste."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003089", "l": "positive regulation of the force of heart contraction by circulating epinephrine-norepinephrine", "d": ["Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099613", "l": "protein localization to cell wall", "d": ["The process of directing proteins towards the cell-wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034294", "l": "sexual spore wall assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a sexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010602", "l": "regulation of 1-aminocyclopropane-1-carboxylate metabolic process", "d": ["Regulation of the chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061562", "l": "cranial ganglion structural organization", "d": ["The process that contributes to creating the structural organization of a cranial ganglion. This process pertains to the physical shaping of a rudimentary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904919", "l": "transmembrane L-cystine transport from lysosomal lumen to cytosol", "d": ["The directed movement of L-cystine from the lysosomal lumen across the lysosomal membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0070542", "l": "response to fatty acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0001798", "l": "positive regulation of type IIa hypersensitivity", "d": ["Any process that activates or increases the frequency, rate or extent of type IIa hypersensitivity, a type of inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045907", "l": "positive regulation of vasoconstriction", "d": ["Any process that activates or increases the frequency, rate or extent of vasoconstriction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905865", "l": "negative regulation of Atg1/ULK1 kinase complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Atg1/ULK1 kinase complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0015768", "l": "maltose transport", "d": ["The directed movement of maltose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the catabolism of glycogen and starch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046260", "l": "trinitrotoluene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of trinitrotoluene, a methylated benzene entity with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060932", "l": "His-Purkinje system cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0048668", "l": "collateral sprouting", "d": ["The process in which outgrowths develop from the shafts of existing axons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032096", "l": "negative regulation of response to food", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0120150", "l": "regulation of mitotic actomyosin contractile ring disassembly", "d": ["Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900632", "l": "tridecane biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tridecane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006382", "l": "adenosine to inosine editing", "d": ["The conversion of an adenosine residue to inosine in an RNA molecule by deamination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0001581", "l": "detection of chemical stimulus involved in sensory perception of sour taste", "d": ["The series of events required for a sour taste stimulus to be received and converted to a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034966", "l": "intronic box H/ACA snoRNA processing", "d": ["Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box H/ACA snoRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002725", "l": "negative regulation of T cell cytokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902964", "l": "positive regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0099640", "l": "axo-dendritic protein transport", "d": ["The directed movement of proteins along microtubules in neuron projections."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061444", "l": "endocardial cushion cell development", "d": ["The process whose specific outcome is the progression of an endocardial cushion cell over time, from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902542", "l": "regulation of protein localization to mitotic spindle pole body", "d": ["Any process that modulates the frequency, rate or extent of protein localization to mitotic spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097083", "l": "vascular associated smooth muscle cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034773", "l": "histone H4-K20 trimethylation", "d": ["The modification of histone H4 by addition of three methyl groups to lysine at position 20 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900118", "l": "negative regulation of execution phase of apoptosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0018106", "l": "peptidyl-histidine phosphorylation", "d": ["The phosphorylation of peptidyl-histidine to form peptidyl-1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine) or peptidyl-3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.157169620444122", "identifiers": [{"i": "GO:0034765", "l": "regulation of monoatomic ion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0040009", "l": "regulation of growth rate", "d": ["Any process that modulates the rate of growth of all or part of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060530", "l": "smooth muscle cell differentiation involved in prostate glandular acinus development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902297", "l": "cell cycle DNA replication DNA unwinding", "d": ["Any DNA unwinding that is involved in cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902979", "l": "mitotic DNA replication termination", "d": ["Any DNA replication termination involved in mitotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900687", "l": "negative regulation of gerfelin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gerfelin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140050", "l": "negative regulation of endocardial cushion to mesenchymal transition", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032043", "l": "mitochondrial DNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043639", "l": "benzoate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061330", "l": "Malpighian tubule stellate cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061952", "l": "midbody abscission", "d": ["The process by which the midbody, the cytoplasmic bridge that connects the two prospective daughter cells, is severed at the end of mitotic cytokinesis, resulting in two separate daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905305", "l": "negative regulation of cardiac myofibril assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1905276", "l": "regulation of epithelial tube formation", "d": ["Any process that modulates the frequency, rate or extent of epithelial tube formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0072339", "l": "lactam biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034382", "l": "chylomicron remnant clearance", "d": ["The process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051086", "l": "chaperone mediated protein folding independent of cofactor", "d": ["The process of assisting in the correct noncovalent assembly of posttranslational proteins and does not depend on additional protein cofactors. This function occurs over one or more cycles of nucleotide-dependent binding and release."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018148", "l": "RNA-protein covalent cross-linking via peptidyl-tyrosine", "d": ["The formation of a covalent cross-link between RNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-RNA)-L-tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0006828", "l": "manganese ion transport", "d": ["The directed movement of manganese (Mn) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010230", "l": "alternative respiration", "d": ["Alternative respiration pathway consumes oxygen, oxidizes NADH to NAD+ and generates water. During electron flow, proton motive force is diminished resulting in fewer molecules of ATP compared to cytochrome pathway. The pathway is found in plants, algae and some protozoa."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090352", "l": "regulation of nitrate assimilation", "d": ["Any process that modulates the rate, frequency, or extent of the uptake, from the environment, of nitrates, inorganic or organic salts and esters of nitric acid and the subsequent reduction of nitrate ion to other, less highly oxidized, inorganic nitrogenous substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900024", "l": "regulation of substrate adhesion-dependent cell spreading", "d": ["Any process that modulates the frequency, rate or extent of substrate adhesion-dependent cell spreading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051563", "l": "smooth endoplasmic reticulum calcium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of calcium ions within the smooth endoplasmic reticulum of a cell or between the smooth endoplasmic reticulum and its surroundings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002722", "l": "negative regulation of B cell cytokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.357413409522593", "identifiers": [{"i": "GO:1904062", "l": "regulation of monoatomic cation transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of cation transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0140418", "l": "effector-mediated modulation of host process by symbiont", "d": ["A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a host structure or process. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.585103934178449", "identifiers": [{"i": "GO:0072028", "l": "nephron morphogenesis", "d": ["The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098717", "l": "pantothenate import across plasma membrane", "d": ["The directed movement of pantothenate from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904430", "l": "negative regulation of t-circle formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of t-circle formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901932", "l": "bicyclogermacrene metabolic process", "d": ["The chemical reactions and pathways involving bicyclogermacrene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904695", "l": "positive regulation of vascular associated smooth muscle contraction", "d": ["Any process that activates or increases the frequency, rate or extent of vascular smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0031279", "l": "regulation of cyclase activity", "d": ["Any process that modulates the frequency, rate or extent of cyclase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990484", "l": "aerobic lactate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the presence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0039504", "l": "suppression by virus of host adaptive immune response", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the adaptive immune response of the host organism, an immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120229", "l": "protein localization to motile cilium", "d": ["A process in which a protein is transported to, or maintained in, a location within a motile cilium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902771", "l": "positive regulation of choline O-acetyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of choline O-acetyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904963", "l": "regulation of phytol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of phytol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015690", "l": "aluminum cation transport", "d": ["The directed movement of aluminum (Al) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901406", "l": "positive regulation of tetrapyrrole catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140655", "l": "mitochondrial proliferation", "d": ["The multiplication of mitochondria, resulting in the expansion of the number of mitochondria within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098957", "l": "anterograde axonal transport of mitochondrion", "d": ["The directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905843", "l": "regulation of cellular response to gamma radiation", "d": ["Any process that modulates the frequency, rate or extent of cellular response to gamma radiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0072017", "l": "distal tubule development", "d": ["The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905093", "l": "cellular response to diosgenin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0099082", "l": "retrograde trans-synaptic signaling by neuropeptide", "d": ["Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070955", "l": "negative regulation of neutrophil mediated killing of symbiont cell", "d": ["Any process that decreases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070625", "l": "zymogen granule exocytosis", "d": ["The release of intracellular molecules contained within the zymogen granule by fusion of the granule with the plasma membrane of the oocyte, requiring calcium ions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009172", "l": "purine deoxyribonucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905051", "l": "regulation of base-excision repair", "d": ["Any process that modulates the frequency, rate or extent of base-excision repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0018873", "l": "atrazine metabolic process", "d": ["The chemical reactions and pathways involving atrazine, a triazine ring-containing compound, widely used as a herbicide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034356", "l": "NAD biosynthesis via nicotinamide riboside salvage pathway", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD) from the vitamin precursor nicotinamide riboside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0002839", "l": "positive regulation of immune response to tumor cell", "d": ["Any process that activates or increases the frequency, rate, or extent of an immune response to tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018956", "l": "phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene", "d": ["The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(R),10(R)-dihydrodiolphenanthrene is the principal intermediate metabolite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0000184", "l": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "d": ["The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901456", "l": "positive regulation of response to toluene", "d": ["Any process that activates or increases the frequency, rate or extent of response to toluene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000347", "l": "positive regulation of hepatocyte proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0001578", "l": "microtubule bundle formation", "d": ["A process that results in a parallel arrangement of microtubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021863", "l": "forebrain neuroblast differentiation", "d": ["The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120067", "l": "pyloric sphincter smooth muscle contraction", "d": ["A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the narrowest part of the pylorus that separates the stomach from the duodenum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075522", "l": "IRES-dependent viral translational initiation", "d": ["Process by which viral mRNA translation is initiated, where a domain in the 5' untranslated region (UTR) of the viral mRNA called an internal ribosome entry site (IRES) binds the host 43S preinitiation complex, circumventing regular cap-dependent translation initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0000915", "l": "actomyosin contractile ring assembly", "d": ["The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042026", "l": "protein refolding", "d": ["The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070756", "l": "positive regulation of interleukin-35 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-35 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006229", "l": "dUTP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dUTP, deoxyuridine (5'-)triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019598", "l": "(R)-mandelate catabolic process to catechol", "d": ["The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including catechol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902700", "l": "pentose catabolic process to butan-1-ol", "d": ["The chemical reactions and pathways resulting in the breakdown of pentose to butan-1-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007503", "l": "fat body development", "d": ["The process whose specific outcome is the progression of the fat body over time, from its formation to the mature structure. A fat body is an insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901413", "l": "regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA", "d": ["Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001280", "l": "positive regulation of unsaturated fatty acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006182", "l": "cGMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyclic GMP, guanosine 3',5'-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905769", "l": "positive regulation of double-stranded telomeric DNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of double-stranded telomeric DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1990344", "l": "secondary cell septum biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a secondary cell septum following nuclear division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060238", "l": "regulation of signal transduction involved in conjugation with cellular fusion", "d": ["Any process that modulates the rate, frequency or extent of pheromone-dependent signal transduction during conjugation with cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048106", "l": "establishment of thoracic bristle planar orientation", "d": ["Orientation along the body surface of bristles, sensory organs originating from a sensory organ precursor cell, such that they all point in a uniform direction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:2001279", "l": "regulation of unsaturated fatty acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of unsaturated fatty acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018935", "l": "aerobic nitrilotriacetate metabolic process", "d": ["The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the presence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048840", "l": "otolith development", "d": ["The process whose specific outcome is the progression of the otolith over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071710", "l": "membrane macromolecule biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a membrane in a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000141", "l": "positive regulation of octopamine signaling pathway involved in response to food", "d": ["Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway involved in response to food."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905811", "l": "negative regulation of excitatory synapse pruning", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse pruning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010434", "l": "bract formation", "d": ["The process that gives rise to a bract. This process pertains to the initial formation of a structure from unspecified parts. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045949", "l": "positive regulation of phosphorus utilization", "d": ["Any process that activates or increases the frequency, rate or extent of phosphorus utilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0006446", "l": "regulation of translational initiation", "d": ["Any process that modulates the frequency, rate or extent of translational initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048647", "l": "polyphenic determination", "d": ["The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental and/or genetic cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090067", "l": "regulation of thalamus size", "d": ["Any process that modulates the size of the thalamus. The thalamus is a part of the diencephalon that is composed of the dorsal thalamus and the ventral thalamus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000265", "l": "positive regulation of blood coagulation, extrinsic pathway", "d": ["Any process that activates or increases the frequency, rate or extent of blood coagulation, extrinsic pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045489", "l": "pectin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0071322", "l": "cellular response to carbohydrate stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0042448", "l": "progesterone metabolic process", "d": ["The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042193", "l": "methylmercury catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of methylmercury (MeHg+), a highly toxic organometal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0010458", "l": "exit from mitosis", "d": ["The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900970", "l": "positive regulation of sarcinapterin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of sarcinapterin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039672", "l": "suppression by virus of host natural killer cell activation", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation in the host."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903112", "l": "positive regulation of single-strand break repair via homologous recombination", "d": ["Any process that activates or increases the frequency, rate or extent of single-strand break repair via homologous recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904179", "l": "positive regulation of adipose tissue development", "d": ["Any process that activates or increases the frequency, rate or extent of adipose tissue development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090124", "l": "N-4 methylation of cytosine", "d": ["The covalent transfer of a methyl group to N-4 of cytosine in a DNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0042093", "l": "T-helper cell differentiation", "d": ["The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097337", "l": "response to ziprasidone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ziprasidone stimulus. Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019749", "l": "cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte", "d": ["The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048293", "l": "regulation of isotype switching to IgE isotypes", "d": ["Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.83044649042801", "identifiers": [{"i": "GO:0018205", "l": "peptidyl-lysine modification", "d": ["The modification of peptidyl-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.986632145964997", "identifiers": [{"i": "GO:0031325", "l": "positive regulation of cellular metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903123", "l": "regulation of thioredoxin peroxidase activity", "d": ["Any process that modulates the frequency, rate or extent of thioredoxin peroxidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1905755", "l": "protein localization to cytoplasmic microtubule", "d": ["A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051071", "l": "4,6-pyruvylated galactose residue metabolic process", "d": ["The chemical reactions and pathways involving the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904020", "l": "regulation of G protein-coupled receptor internalization", "d": ["Any process that modulates the frequency, rate or extent of G protein-coupled receptor internalization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0034490", "l": "basic amino acid transmembrane import into vacuole", "d": ["The directed movement of basic amino acids into the vacuole across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0033559", "l": "unsaturated fatty acid metabolic process", "d": ["The chemical reactions and pathways involving an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0060572", "l": "morphogenesis of an epithelial bud", "d": ["The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0030261", "l": "chromosome condensation", "d": ["The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.661622235043069", "identifiers": [{"i": "GO:0006109", "l": "regulation of carbohydrate metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106300", "l": "protein-DNA covalent cross-linking repair", "d": ["The removal of covalent cross-link between DNA and a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019380", "l": "3-phenylpropionate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-phenylpropionate, the anion of phenylpropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902429", "l": "positive regulation of water channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of water channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010519", "l": "negative regulation of phospholipase activity", "d": ["Any process that decreases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901841", "l": "regulation of high voltage-gated calcium channel activity", "d": ["Any process that modulates the frequency, rate or extent of high voltage-gated calcium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0042161", "l": "lipoprotein oxidation", "d": ["The modification of a lipoprotein by oxidation of one or more amino acids or the lipid group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0019695", "l": "choline metabolic process", "d": ["The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.050408934017838", "identifiers": [{"i": "GO:0099111", "l": "microtubule-based transport", "d": ["A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000571", "l": "regulation of interleukin-4-dependent isotype switching to IgE isotypes", "d": ["Any process that modulates the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048100", "l": "wing disc anterior/posterior pattern formation", "d": ["The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060743", "l": "epithelial cell maturation involved in prostate gland development", "d": ["The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905327", "l": "tracheoesophageal septum formation", "d": ["The process that gives rise to the tracheoesophageal septum. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0046822", "l": "regulation of nucleocytoplasmic transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0044718", "l": "siderophore transmembrane transport", "d": ["The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, from one side of a membrane to the other, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905707", "l": "negative regulation of mitochondrial ATP synthesis coupled proton transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905851", "l": "negative regulation of backward locomotion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of backward locomotion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0044414", "l": "suppression of host defenses by symbiont", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host defense(s) by active mechanisms that normally result in the shutting down of a host pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0055017", "l": "cardiac muscle tissue growth", "d": ["The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060330", "l": "regulation of response to type II interferon", "d": ["Any process that modulates the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0003365", "l": "establishment of cell polarity involved in ameboidal cell migration", "d": ["The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1900037", "l": "regulation of cellular response to hypoxia", "d": ["Any process that modulates the frequency, rate or extent of cellular response to hypoxia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0046666", "l": "retinal cell programmed cell death", "d": ["Programmed cell death that occurs in the developing retina."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905001", "l": "negative regulation of membrane repolarization during atrial cardiac muscle cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:1990849", "l": "vacuolar localization", "d": ["Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:1901577", "l": "regulation of alkane biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of alkane biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0046173", "l": "polyol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071730", "l": "beak formation", "d": ["The process that gives rise to the beak. This process pertains to the initial formation of a structure from unspecified parts. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072120", "l": "pronephros maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0060841", "l": "venous blood vessel development", "d": ["The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043278", "l": "response to morphine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051041", "l": "positive regulation of calcium-independent cell-cell adhesion", "d": ["Any process that activates or increases the frequency, rate or extent of calcium-independent cell-cell adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0043982", "l": "histone H4-K8 acetylation", "d": ["The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904214", "l": "positive regulation of iodide transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of iodide transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.154928939654667", "identifiers": [{"i": "GO:0048858", "l": "cell projection morphogenesis", "d": ["The process in which the anatomical structures of a cell projection are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006051", "l": "N-acetylmannosamine metabolic process", "d": ["The chemical reactions and pathways involving N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.777964009505382", "identifiers": [{"i": "GO:0008277", "l": "regulation of G protein-coupled receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902169", "l": "cellular response to catechin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002810", "l": "regulation of antifungal peptide biosynthetic process", "d": ["Any process that modulates the frequency, rate, or extent of antifungal peptide biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019331", "l": "anaerobic respiration, using ammonium as electron donor", "d": ["The oxidation of ammonium (NH4) to nitrogen (N2) in the absence of oxygen, using nitrite (NO2) as the electron acceptor. It is suggested that hydroxylamine and ammonium are combined to yield hydrazine, which is subsequently oxidized to N2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0003338", "l": "metanephros morphogenesis", "d": ["The process in which the anatomical structures of the metanephros are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000057", "l": "negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001926", "l": "positive regulation of B-1 B cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of B-1 B cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046482", "l": "para-aminobenzoic acid metabolic process", "d": ["The chemical reactions and pathways involving para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902163", "l": "negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902182", "l": "shoot apical meristem development", "d": ["The process whose specific outcome is the progression of a shoot apical meristem over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001712", "l": "ectodermal cell fate commitment", "d": ["The cell differentiation process that results in commitment of a cell to become part of the ectoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905860", "l": "positive regulation of heparan sulfate proteoglycan binding", "d": ["Any process that activates or increases the frequency, rate or extent of heparan sulfate proteoglycan binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009176", "l": "pyrimidine deoxyribonucleoside monophosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035167", "l": "larval lymph gland hemopoiesis", "d": ["The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.062480095235458", "identifiers": [{"i": "GO:0044089", "l": "positive regulation of cellular component biogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904586", "l": "cellular response to putrescine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002647", "l": "negative regulation of central tolerance induction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of central tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0032954", "l": "regulation of cytokinetic process", "d": ["Any process that modulates the frequency, rate or extent of a cytokinetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "44.354808626477222", "identifiers": [{"i": "GO:0140352", "l": "export from cell", "d": ["The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002936", "l": "bradykinin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the peptide hormone bradykinin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905423", "l": "positive regulation of plant organ morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of plant organ morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990638", "l": "response to granulocyte colony-stimulating factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905137", "l": "regulation of viral DNA genome packaging via site-specific sequence recognition", "d": ["Any process that modulates the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0035987", "l": "endodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046170", "l": "methanol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901498", "l": "response to tetralin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetralin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042707", "l": "ocellus photoreceptor cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into photoreceptor cell in the ocellus. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120176", "l": "positive regulation of torso signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the torso signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072204", "l": "cell-cell signaling involved in metanephros development", "d": ["Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904031", "l": "positive regulation of cyclin-dependent protein kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050494", "l": "GSI anchor biosynthetic process via N-glycyl-glycosylsphingolipidinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:0043937", "l": "regulation of sporulation", "d": ["Any process that modulates the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071280", "l": "cellular response to copper ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0060837", "l": "blood vessel endothelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0099134", "l": "chimeric sorocarp development", "d": ["Development of a sorocarp formed by aggregation of cells with different genotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904932", "l": "negative regulation of cartilage condensation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cartilage condensation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0007386", "l": "compartment pattern specification", "d": ["The regionalization process in which embryonic segments are divided into compartments that will result in differences in cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0033046", "l": "negative regulation of sister chromatid segregation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902848", "l": "negative regulation of neuronal signal transduction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neuronal signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0009062", "l": "fatty acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:1905770", "l": "regulation of mesodermal cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of mesodermal cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010099", "l": "regulation of photomorphogenesis", "d": ["Any process that modulates the rate or extent of photomorphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902987", "l": "negative regulation of lysine biosynthetic process via aminoadipic acid", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015839", "l": "cadaverine transport", "d": ["The directed movement of cadaverine, 1,5-pentanediamine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061698", "l": "protein deglutarylation", "d": ["The removal of a glutaryl group (CO-CH2-CH2-CH2-CO) from a residue in a peptide or protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006272", "l": "leading strand elongation", "d": ["The process in which an existing DNA strand is extended continuously in a 5' to 3' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Leading strand elongation proceeds in the same direction as the replication fork."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110159", "l": "regulation of mitotic spindle formation (spindle phase one)", "d": ["Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0008306", "l": "associative learning", "d": ["Learning by associating a stimulus (the cause) with a particular outcome (the effect)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0051278", "l": "fungal-type cell wall polysaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the polysaccharides which make up the fungal-type cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903579", "l": "negative regulation of ATP metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ATP metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903419", "l": "protein localization to cortical endoplasmic reticulum", "d": ["A process in which a protein is transported to, or maintained in, a location within a cortical endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019324", "l": "L-lyxose metabolic process", "d": ["The chemical reactions and pathways involving L-lyxose, the L-enantiomer of aldopentose lyxo-pentose, the C-2 epimer of xylose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905601", "l": "negative regulation of receptor-mediated endocytosis involved in cholesterol transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003095", "l": "pressure natriuresis", "d": ["The process in which the volume of blood increases renal pressure and thereby results in both an increase in urine volume (diuresis) and an increase in the amount of sodium excreted in the urine (natriuresis)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048337", "l": "positive regulation of mesodermal cell fate specification", "d": ["Any process that activates or increases the frequency, rate or extent of mesoderm cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048351", "l": "negative regulation of paraxial mesodermal cell fate specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044542", "l": "plasminogen activation in another organism", "d": ["The chemical reactions and pathways performed by an organism resulting in the processing of inactive plasminogen to active plasmin in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090451", "l": "cotyledon boundary formation", "d": ["The process in which boundaries between a cotyledon and the surrounding tissue are established and maintained."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0060180", "l": "female mating behavior", "d": ["The specific behavior of a female organism that is associated with reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010224", "l": "response to UV-B", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000869", "l": "positive regulation of estrone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of estrone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010084", "l": "specification of animal organ axis polarity", "d": ["The process in which the polarity of an animal organ axis is specified."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072327", "l": "vulval cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000959", "l": "positive regulation of cyclodextrin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cyclodextrin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904233", "l": "negative regulation of aconitate hydratase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aconitate hydratase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019496", "l": "serine-isocitrate lyase pathway", "d": ["A one-carbon metabolic process in which acetyl-CoA is produced from formaldehyde and carbon dioxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903977", "l": "positive regulation of glial cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of glial cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0016139", "l": "glycoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072037", "l": "mesenchymal stem cell differentiation involved in nephron morphogenesis", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048548", "l": "regulation of pinocytosis", "d": ["Any process that modulates the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.83044649042801", "identifiers": [{"i": "GO:0044087", "l": "regulation of cellular component biogenesis", "d": ["Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0051643", "l": "endoplasmic reticulum localization", "d": ["Any process in which endoplasmic reticulum is transported to, and/or maintained in, a specific location within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046602", "l": "regulation of mitotic centrosome separation", "d": ["Any process that modulates the frequency, rate or extent of the separation of duplicated centrosome components at the beginning of mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010904", "l": "regulation of UDP-glucose catabolic process", "d": ["Any process that modulates the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.503963827996756", "identifiers": [{"i": "GO:0051960", "l": "regulation of nervous system development", "d": ["Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0008584", "l": "male gonad development", "d": ["The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903465", "l": "positive regulation of mitotic cell cycle DNA replication", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048942", "l": "posterior lateral line nerve glial cell morphogenesis involved in differentiation", "d": ["The process in which the structures of a glial cell in the posterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the posterior lateral line nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060615", "l": "mammary gland bud formation", "d": ["The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0097501", "l": "stress response to metal ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a metal ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010846", "l": "activation of reciprocal meiotic recombination", "d": ["Any process that starts the inactive process of reciprocal meiotic recombination. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010249", "l": "auxin conjugate metabolic process", "d": ["The chemical reactions and pathways involving auxin conjugates, a bound form of auxin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035491", "l": "positive regulation of leukotriene production involved in inflammatory response", "d": ["Any process that increases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0070705", "l": "RNA nucleotide insertion", "d": ["The modification of an RNA molecule by insertion of one or more nucleotides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001297", "l": "N(omega)-methyl-L-arginine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N(omega)-methyl-L-arginine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090634", "l": "microglial cell mediated cytotoxicity", "d": ["The directed killing of a target cell by a microglial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0003209", "l": "cardiac atrium morphogenesis", "d": ["The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019481", "l": "L-alanine catabolic process, by transamination", "d": ["The chemical reactions and pathways resulting in the breakdown of L-alanine by transamination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003391", "l": "amphid sensory organ dendrite retrograde extension", "d": ["The progression of an amphid sensory organ's neuronal dendrite over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000867", "l": "regulation of estrone secretion", "d": ["Any process that modulates the frequency, rate or extent of estrone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035347", "l": "negative regulation of hypoxanthine transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042670", "l": "retinal cone cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099627", "l": "neurotransmitter receptor cycle", "d": ["The process during which neurotransmitter receptors, anchored in some region of the synaptic membrane, are recycled via the endosome. This cycle includes release from anchoring, diffusion in the synaptic membrane to an endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent anchoring (trapping)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099578", "l": "regulation of translation at postsynapse, modulating synaptic transmission", "d": ["Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0072172", "l": "mesonephric tubule formation", "d": ["The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0050850", "l": "positive regulation of calcium-mediated signaling", "d": ["Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990551", "l": "mitochondrial 2-oxoadipate transmembrane transport", "d": ["The process in which 2-oxoadipate is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0008356", "l": "asymmetric cell division", "d": ["The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0099504", "l": "synaptic vesicle cycle", "d": ["A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060447", "l": "bud outgrowth involved in lung branching", "d": ["The process in which a region of the lung epithelium initiates an outgrowth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090400", "l": "stress-induced premature senescence", "d": ["A cellular senescence process associated with the dismantling of a cell as a response to environmental factors such as hydrogen peroxide or X-rays."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072233", "l": "metanephric thick ascending limb development", "d": ["The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140466", "l": "iron-sulfur cluster export from the mitochondrion", "d": ["The directed movement of iron sulfur clusters from inside the mitochondrion into the cytosol by crossing the inner mitochondrial membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900263", "l": "negative regulation of DNA-directed DNA polymerase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA-directed DNA polymerase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003168", "l": "Purkinje myocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019680", "l": "L-methylmalonyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0032239", "l": "regulation of nucleobase-containing compound transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060124", "l": "positive regulation of growth hormone secretion", "d": ["Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045428", "l": "regulation of nitric oxide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015860", "l": "purine nucleoside transmembrane transport", "d": ["The process in which a purine nucleoside is transported across a membrane. A purine nucleoside is a purine base covalently bonded to a ribose or deoxyribose sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.377409517593492", "identifiers": [{"i": "GO:0051172", "l": "negative regulation of nitrogen compound metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902394", "l": "positive regulation of exodeoxyribonuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of exodeoxyribonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006526", "l": "arginine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900440", "l": "regulation of filamentous growth of a population of unicellular organisms in response to neutral pH", "d": ["Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902530", "l": "positive regulation of protein linear polyubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein linear polyubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048885", "l": "neuromast deposition", "d": ["The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in a developing lateral line."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.618854952666041", "identifiers": [{"i": "GO:0007283", "l": "spermatogenesis", "d": ["The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0120046", "l": "regulation of protein localization to medial cortical node", "d": ["Any process that modulates the frequency, rate or extent of protein localization to a medial cortical node."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900338", "l": "positive regulation of methane biosynthetic process from carbon monoxide", "d": ["Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from carbon monoxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900627", "l": "negative regulation of arugosin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of arugosin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098818", "l": "hyperpolarization of postsynaptic membrane", "d": ["A process that hyerpolarizes a postsynaptic membrane relative to its resting potential. This has an inhibitory effect on the post-synaptic cell, moving the membrane potential away from the firing threshold."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032189", "l": "maintenance of actomyosin contractile ring localization", "d": ["Any process in which an actomyosin contractile ring is maintained in a location and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034036", "l": "purine ribonucleoside bisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:0048580", "l": "regulation of post-embryonic development", "d": ["Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001262", "l": "positive regulation of semaphorin-plexin signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010786", "l": "clathrin coating of Golgi vesicle, trans-Golgi to endosome targeting", "d": ["The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the trans-Golgi to the endosome, forming a vesicle coat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0021936", "l": "regulation of cerebellar granule cell precursor proliferation", "d": ["The process that modulates the frequency, rate or extent of granule cell precursor proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051202", "l": "phytochromobilin metabolic process", "d": ["The chemical reactions and pathways involving phytochromobilin, the linear tetrapyrrole chromophore required for plant phytochrome photoactivity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1905456", "l": "regulation of lymphoid progenitor cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900870", "l": "tatiopterin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tatiopterin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0007028", "l": "cytoplasm organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032187", "l": "actomyosin contractile ring localization", "d": ["The process in which a contractile ring is positioned or maintained in a specific location, in the context of cytokinesis that takes place as part of a cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048921", "l": "posterior lateral line neuromast cupula development", "d": ["The process whose specific outcome is the progression of the posterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046412", "l": "phenylmercury acetate metabolic process", "d": ["The chemical reactions and pathways involving phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044315", "l": "protein secretion by the type VII secretion system", "d": ["The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type VII protein secretion system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044521", "l": "envenomation resulting in muscle damage in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant muscle damage in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008615", "l": "pyridoxine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990859", "l": "cellular response to endothelin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034139", "l": "regulation of toll-like receptor 3 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 3 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090160", "l": "Golgi to lysosome transport", "d": ["The directed movement of substances from the Golgi to lysosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014008", "l": "positive regulation of microglia differentiation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902141", "l": "cellular response to inositol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0009561", "l": "megagametogenesis", "d": ["The process whose specific outcome is the progression of the embryo sac over time, from its formation as the megaspore to the mature structure. The process begins when three of the four haploid megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0002830", "l": "positive regulation of type 2 immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of a type 2 immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106048", "l": "spermidine deacetylation", "d": ["The modification of acetylspermadine by the removal of acetyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019653", "l": "anaerobic purine nucleobase catabolic process", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of purine nucleobases, yielding energy in the form of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061273", "l": "mesonephric distal tubule morphogenesis", "d": ["The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034144", "l": "negative regulation of toll-like receptor 4 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000004", "l": "regulation of metanephric S-shaped body morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of metanephric S-shaped body morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060838", "l": "lymphatic endothelial cell fate commitment", "d": ["The commitment of a venous blood vessel endothelial cell to a lymphatic endothelial cell fate and its capacity to differentiate into a lymphatic endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030920", "l": "peptidyl-serine acetylation", "d": ["The acetylation of peptidyl-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902213", "l": "positive regulation of prolactin signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000193", "l": "positive regulation of fatty acid transport", "d": ["Any process that activates or increases the frequency, rate or extent of fatty acid transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072731", "l": "cellular response to papulacandin B", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0016199", "l": "axon midline choice point recognition", "d": ["The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007540", "l": "sex determination, establishment of X:A ratio", "d": ["The developmental process in which an organism senses the number of X chromosomes and autosomes in its genomic complement and responds to it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061301", "l": "cerebellum vasculature morphogenesis", "d": ["The process in which the vasculature of the cerebellum is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903515", "l": "calcium ion transport from cytosol to endoplasmic reticulum", "d": ["The directed movement of calcium ion from cytosol to endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009232", "l": "riboflavin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060325", "l": "face morphogenesis", "d": ["The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905127", "l": "negative regulation of axo-dendritic protein transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902902", "l": "negative regulation of autophagosome assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0072526", "l": "pyridine-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000702", "l": "regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation", "d": ["Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019090", "l": "mitochondrial rRNA export from mitochondrion", "d": ["The process in which a rRNA, ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044536", "l": "envenomation resulting in depletion of circulating fibrinogen in another organism", "d": ["The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with a reduction in the quantity of fibrinogen found in the bloodstream of the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000489", "l": "regulation of hepatic stellate cell activation", "d": ["Any process that modulates the frequency, rate or extent of hepatic stellate cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1902486", "l": "protein localization to growing cell tip", "d": ["A process in which a protein is transported to, or maintained in, a location within a growing cell tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045894", "l": "negative regulation of mating-type specific transcription, DNA-templated", "d": ["Any mating-type specific process that stops, prevents or reduces the rate of cellular DNA-templated transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015955", "l": "pyrimidine deoxyribonucleotide interconversion", "d": ["The chemical reactions and pathways by which a pyrimidine deoxyribonucleotide is synthesized from another pyrimidine deoxyribonucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0042144", "l": "vacuole fusion, non-autophagic", "d": ["The fusion of two vacuole membranes to form a single vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150139", "l": "positive regulation of interleukin-37 production", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-37 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030538", "l": "embryonic genitalia morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the genitalia are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070399", "l": "wall teichoic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010082", "l": "regulation of root meristem growth", "d": ["Any process involved in maintaining the size and shape of a root meristem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060008", "l": "Sertoli cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120323", "l": "lipid ubiquitination", "d": ["The process in which one or more ubiquitin groups are added to a lipid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010789", "l": "meiotic sister chromatid cohesion involved in meiosis I", "d": ["The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120276", "l": "regulation of cerebral blood circulation", "d": ["Any process that modulates the frequency, rate or extent of cerebral blood circulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1905203", "l": "regulation of connective tissue replacement", "d": ["Any process that modulates the frequency, rate or extent of connective tissue replacement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0046351", "l": "disaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of disaccharides, sugars composed of two monosaccharide units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903511", "l": "orotic acid metabolic process", "d": ["The chemical reactions and pathways involving orotic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.161881760686384", "identifiers": [{"i": "GO:0002312", "l": "B cell activation involved in immune response", "d": ["The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061909", "l": "autophagosome-lysosome fusion", "d": ["The process in which autophagosomes, double-membraned vesicles containing cytoplasmic material, fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003187", "l": "ventriculo bulbo valve morphogenesis", "d": ["The process in which the structure of the ventriculo bulbo valve is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035462", "l": "determination of left/right asymmetry in diencephalon", "d": ["The establishment of the diencephalon with respect to the left and right halves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902089", "l": "cell wall polysaccharide catabolic process involved in lateral root development", "d": ["Any cell wall polysaccharide catabolic process that is involved in lateral root development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099555", "l": "trans-synaptic signaling by nitric oxide, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0051790", "l": "short-chain fatty acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a fatty acid with an aliphatic tail of less than 6 carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061429", "l": "positive regulation of transcription from RNA polymerase II promoter by oleic acid", "d": ["Any process involving oleic acid that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051210", "l": "isotropic cell growth", "d": ["The process in which a cell irreversibly increases in size uniformly in all directions. In general, a rounded cell morphology reflects isotropic cell growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021965", "l": "spinal cord ventral commissure morphogenesis", "d": ["The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033346", "l": "asparagine catabolic process via 2-oxosuccinamate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxosuccinamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900848", "l": "positive regulation of naphtho-gamma-pyrone biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900854", "l": "positive regulation of terrequinone A biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of terrequinone A biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043688", "l": "conversion of aspartyl-tRNA to asparaginyl-tRNA", "d": ["The modification process that results in the conversion of aspartate charged on a tRNA(Asn) to asparaginyl-tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1900749", "l": "(R)-carnitine transport", "d": ["The directed movement of a (R)-carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044871", "l": "negative regulation by host of viral glycoprotein metabolic process", "d": ["A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral glycoprotein metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000596", "l": "negative regulation of optic nerve formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of optic nerve formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060393", "l": "regulation of pathway-restricted SMAD protein phosphorylation", "d": ["Any process that modulates the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0052800", "l": "bicyclic nitroimidazole catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a bicyclic nitroimidazole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0060073", "l": "micturition", "d": ["The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905499", "l": "trichome papilla formation", "d": ["The aggregation, arrangement and bonding together of a set of components to form a trichome papilla."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0072132", "l": "mesenchyme morphogenesis", "d": ["The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.011351901223186", "identifiers": [{"i": "GO:0051050", "l": "positive regulation of transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0032638", "l": "interleukin-9 production", "d": ["The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.990900157612501", "identifiers": [{"i": "GO:0006937", "l": "regulation of muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900937", "l": "positive regulation of nonadec-1-ene biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of nonadec-1-ene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0120009", "l": "intermembrane lipid transfer", "d": ["The transport of lipids between membranes in which a lipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.465910785634115", "identifiers": [{"i": "GO:0019882", "l": "antigen processing and presentation", "d": ["The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060737", "l": "prostate gland morphogenetic growth", "d": ["The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010905", "l": "negative regulation of UDP-glucose catabolic process", "d": ["Any process that decreases the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007344", "l": "pronuclear fusion", "d": ["The merging of two pronuclei in a fertilized egg to fuse and produce a single zygotic genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000475", "l": "maturation of 2S rRNA", "d": ["Any process involved in the maturation of a precursor 2S ribosomal RNA (rRNA) molecule into a mature 2S rRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010066", "l": "ground meristem histogenesis", "d": ["The formation of the primary meristem or meristematic tissue that gives rise to the ground tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0002709", "l": "regulation of T cell mediated immunity", "d": ["Any process that modulates the frequency, rate, or extent of T cell mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903108", "l": "regulation of mitochondrial transcription", "d": ["Any process that modulates the frequency, rate or extent of transcription occuring in the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019803", "l": "peptidyl-aspartic acid carboxylation", "d": ["The carboxylation of peptidyl-aspartic acid to form peptidyl-L-beta-carboxyaspartic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072254", "l": "metanephric glomerular mesangial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the metanephros as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903389", "l": "negative regulation of synaptic vesicle uncoating", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle uncoating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045971", "l": "positive regulation of juvenile hormone catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0002762", "l": "negative regulation of myeloid leukocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902551", "l": "regulation of catalase activity", "d": ["Any process that modulates the frequency, rate or extent of catalase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902416", "l": "positive regulation of mRNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000091", "l": "negative regulation of mesonephric glomerular mesangial cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902425", "l": "positive regulation of attachment of mitotic spindle microtubules to kinetochore", "d": ["Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.442476542024195", "identifiers": [{"i": "GO:0030099", "l": "myeloid cell differentiation", "d": ["The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0039519", "l": "modulation by virus of host autophagy", "d": ["Any process in which a virus effect a change in the frequency, rate or extent of autophagy in the host."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032962", "l": "positive regulation of inositol trisphosphate biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075193", "l": "regulation of haustorium mother cell formation", "d": ["Any process that modulates the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0170006", "l": "lipoate transmembrane transport", "d": ["The process in which lipoate is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120062", "l": "positive regulation of gastric emptying", "d": ["Any process that increases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0042478", "l": "regulation of eye photoreceptor cell development", "d": ["Any process that modulates the frequency, rate or extent of eye photoreceptor development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1990066", "l": "energy quenching", "d": ["The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted by nonphotochemical quenching or chlorophyll fluorescence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1901298", "l": "regulation of hydrogen peroxide-mediated programmed cell death", "d": ["Any process that modulates the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010253", "l": "UDP-rhamnose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060948", "l": "cardiac vascular smooth muscle cell development", "d": ["The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell over time, from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000747", "l": "negative regulation of defecation rhythm", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of defecation rhythm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030152", "l": "bacteriocin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1902683", "l": "regulation of receptor localization to synapse", "d": ["Any process that modulates the frequency, rate or extent of receptor localization to synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106092", "l": "glial cell projection elongation involved in axon ensheathment", "d": ["The extension of a glial cell process or projection to wrap around an axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039545", "l": "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity", "d": ["Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host MAVS (mitochondrial antiviral signaling protein). MAVS is a signal transducer that lies downstream of the viral RNA receptors MDA-5 and RIG-I to coordinate host innate immune responses."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.651613913496419", "identifiers": [{"i": "GO:0097205", "l": "renal filtration", "d": ["A renal system process in which fluid circulating through the body is filtered through a barrier system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900791", "l": "shamixanthone metabolic process", "d": ["The chemical reactions and pathways involving shamixanthone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070425", "l": "negative regulation of nucleotide-binding oligomerization domain containing signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002541", "l": "activation of plasma proteins involved in acute inflammatory response", "d": ["Any process activating plasma proteins by proteolysis as part of an acute inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0007031", "l": "peroxisome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903771", "l": "positive regulation of beta-galactosidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of beta-galactosidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903562", "l": "microtubule bundle formation involved in mitotic spindle midzone assembly", "d": ["Any microtubule bundle formation that is involved in spindle midzone assembly involved in mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032118", "l": "horsetail-astral microtubule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the horsetail-astral array, a structure of astral microtubules that emanates from the spindle pole body during meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150035", "l": "regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission", "d": ["Any process that modulates the frequency, rate or extent of trans-synaptic signaling by BDNF, modulating synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001029", "l": "regulation of cellular glucuronidation", "d": ["Any process that modulates the frequency, rate or extent of cellular glucuronidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0034063", "l": "stress granule assembly", "d": ["The aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061328", "l": "posterior Malpighian tubule development", "d": ["The process whose specific outcome is the progression of the posterior Malpighian tubule over time, from its formation to the mature structure. The pair of posterior tubules arise from a ventrolateral region of the embryonic hindgut and project backwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.116918913335823", "identifiers": [{"i": "GO:0042098", "l": "T cell proliferation", "d": ["The expansion of a T cell population by cell division. Follows T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0070646", "l": "protein modification by small protein removal", "d": ["A protein modification process in which one or more covalently attached groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are removed from a target protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905385", "l": "negative regulation of protein localization to presynapse", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903559", "l": "3-cyano-L-alanine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-cyano-L-alanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901258", "l": "positive regulation of macrophage colony-stimulating factor production", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007036", "l": "vacuolar calcium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009652", "l": "thigmotropism", "d": ["The movement of an organism, or part of an organism, such as leaves or tendrils, in response to a touch stimulus, usually toward or away from it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.316418070386277", "identifiers": [{"i": "GO:0043086", "l": "negative regulation of catalytic activity", "d": ["Any process that stops or reduces the activity of an enzyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043464", "l": "malolactic fermentation", "d": ["The anaerobic enzymatic conversion of L-malate to L-lactate and carbon dioxide, yielding energy in the form of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034034", "l": "purine nucleoside bisphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:0048437", "l": "floral organ development", "d": ["The process whose specific outcome is the progression of the floral organ over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0106106", "l": "cold-induced thermogenesis", "d": ["The process by which heat is generated by increasing metabolism in response to cold ambient temperatures in order to maintain a stable core body temperature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0032606", "l": "type I interferon production", "d": ["The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046878", "l": "positive regulation of saliva secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of saliva."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.426153789046865", "identifiers": [{"i": "GO:0002524", "l": "hypersensitivity", "d": ["An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0015759", "l": "beta-glucoside transport", "d": ["The directed movement of beta-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070642", "l": "vitamin D5 metabolic process", "d": ["The chemical reactions and pathways involving vitamin D5, (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4S)-4-ethyl-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-1-cyclohexanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904863", "l": "regulation of beta-catenin-TCF complex assembly", "d": ["Any process that modulates the frequency, rate or extent of beta-catenin-TCF complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904613", "l": "cellular response to 2,3,7,8-tetrachlorodibenzodioxine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015950", "l": "purine nucleotide interconversion", "d": ["The chemical reactions and pathways by which a purine nucleotide is synthesized from another purine nucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0060706", "l": "cell differentiation involved in embryonic placenta development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060735", "l": "regulation of eIF2 alpha phosphorylation by dsRNA", "d": ["Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140654", "l": "tryprostatin A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tryprostatin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045186", "l": "zonula adherens assembly", "d": ["Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014011", "l": "Schwann cell proliferation involved in axon regeneration", "d": ["The multiplication or reproduction of Schwann cells by cell division, resulting in the expansion of their population in response to an axonal lesion. The newly generated Schwann cells support subsequent axon regeneration in the peripheral nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062085", "l": "positive regulation of capsule polysaccharide biosynthetic process", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000157", "l": "negative regulation of ubiquitin-specific protease activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061272", "l": "mesonephric connecting tubule development", "d": ["The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071962", "l": "mitotic sister chromatid cohesion, centromeric", "d": ["The cell cycle process in which centromeres of sister chromatids are joined during mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035040", "l": "sperm nuclear envelope removal", "d": ["Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0009753", "l": "response to jasmonic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0072003", "l": "kidney rudiment formation", "d": ["The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032913", "l": "negative regulation of transforming growth factor beta3 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018244", "l": "protein N-linked glycosylation via tryptophan", "d": ["The glycosylation of protein via peptidyl-tryptophan, 1'-glycosyl-L-tryptophan; results in the formation of an (S)-2-amino-3-(1-D-mannopyranosyloxy-1H-indol-3-yl)propanoic acid residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034214", "l": "protein hexamerization", "d": ["The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014038", "l": "regulation of Schwann cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of Schwann cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903180", "l": "negative regulation of dopamine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0034397", "l": "telomere localization", "d": ["Any process in which a telomere is transported to, and/or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000929", "l": "positive regulation of cellodextrin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellodextrin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002486", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-independent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following transport from the cytosol via a TAP-independent pathway. Class I here refers to classical class I molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140516", "l": "mitotic nuclear pore complex disassembly", "d": ["The mitotic cell cycle process in which the controlled breakdown of the nuclear pores occurs during open or closed mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007558", "l": "regulation of juvenile hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of juvenile hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0098724", "l": "symmetric stem cell division", "d": ["Symmetric division of a stem cell to produce two stem cells of the same type as the parent. Symmetric stem cell division is necessary for amplification of stem cell populations in the absence of sources of stem cells external to an existing population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0050959", "l": "echolocation", "d": ["Echolocation is the method used by some animals (e.g. bats, dolphins and some whales) to determine the location of something by measuring the time it takes for an echo to return from it. These animals emit sound waves and listen for the echo, calculating the distance to the object from the time lapse between sound emission and the echo returning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0008049", "l": "male courtship behavior", "d": ["The behavior of a male, for the purpose of attracting a sexual partner. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033169", "l": "histone H3-K9 demethylation", "d": ["The modification of histone H3 by the removal of a methyl group from lysine at position 9 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904319", "l": "negative regulation of smooth muscle contraction involved in micturition", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.672305786814945", "identifiers": [{"i": "GO:0048638", "l": "regulation of developmental growth", "d": ["Any process that modulates the frequency, rate or extent of developmental growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003410", "l": "anterior rotation of the optic cup", "d": ["A 90 degree-rotation of the optic cup resulting in its alignment with the anterior-posterior body axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2000881", "l": "regulation of starch catabolic process", "d": ["Any process that modulates the frequency, rate or extent of starch catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901548", "l": "positive regulation of synaptic vesicle lumen acidification", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle lumen acidification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045018", "l": "retrograde transport, vacuole to Golgi", "d": ["The directed movement of substances from the vacuole to the trans-Golgi network; this occurs in yeast via the prevacuolar/endosomal compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0001912", "l": "positive regulation of leukocyte mediated cytotoxicity", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte mediated cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003336", "l": "corneocyte desquamation", "d": ["The delamination process that results in the shedding of a corneocyte from the surface of the epidermis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009195", "l": "pyrimidine ribonucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000791", "l": "negative regulation of mesenchymal cell proliferation involved in lung development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0007619", "l": "courtship behavior", "d": ["The behavior of an organism for the purpose of attracting sexual partners."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036280", "l": "cellular response to L-canavanine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus. L-canavanine is L-homoserine substituted at oxygen with a guanidino (carbamimidamido) group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903893", "l": "positive regulation of ATF6-mediated unfolded protein response", "d": ["Any process that activates or increases the frequency, rate or extent of the ATF6-mediated unfolded protein response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0042402", "l": "cellular biogenic amine catabolic process", "d": ["The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.783030043623796", "identifiers": [{"i": "GO:0017157", "l": "regulation of exocytosis", "d": ["Any process that modulates the frequency, rate or extent of exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097394", "l": "telomeric repeat-containing RNA transcription by RNA polymerase II", "d": ["The synthesis of telomeric repeat-containing RNA from a DNA template by RNA polymerase II (Pol II), originating at a Pol II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070145", "l": "mitochondrial asparaginyl-tRNA aminoacylation", "d": ["The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055130", "l": "D-alanine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-alanine, the D-enantiomer of the amino acid alanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905126", "l": "regulation of axo-dendritic protein transport", "d": ["Any process that modulates the frequency, rate or extent of axo-dendritic protein transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905870", "l": "positive regulation of 3'-UTR-mediated mRNA stabilization", "d": ["Any process that activates or increases the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106129", "l": "positive regulation of store-operated calcium entry", "d": ["Any process that activates or increases the frequency, rate or extent of store-operated calcium entry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904125", "l": "convergent extension involved in rhombomere morphogenesis", "d": ["Any convergent extension that is involved in rhombomere morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110102", "l": "ribulose bisphosphate carboxylase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a ribulose bisphosphate carboxylase complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018889", "l": "2-chloro-N-isopropylacetanilide metabolic process", "d": ["The chemical reactions and pathways involving 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0044073", "l": "modulation by symbiont of host translation", "d": ["The process in which a symbiont organism effects a change in translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048798", "l": "swim bladder inflation", "d": ["The expansion of the swim bladder by trapped gases. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061103", "l": "carotid body glomus cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "48.51091487091881", "identifiers": [{"i": "GO:0022600", "l": "digestive system process", "d": ["A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0052025", "l": "modification by symbiont of host cell membrane", "d": ["The process in which an organism effects a change in the structure or function of a host cellular membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0060648", "l": "mammary gland bud morphogenesis", "d": ["The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:1903335", "l": "regulation of vacuolar transport", "d": ["Any process that modulates the frequency, rate or extent of vacuolar transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901255", "l": "nucleotide-excision repair involved in interstrand cross-link repair", "d": ["Any nucleotide-excision repair that is involved in interstrand cross-link repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061362", "l": "negative regulation of maintenance of bipolar cell polarity regulating cell shape", "d": ["Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098529", "l": "neuromuscular junction development, skeletal muscle fiber", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction that targets a skeletal muscle fiber."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000624", "l": "positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "d": ["Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900123", "l": "regulation of nodal receptor complex assembly", "d": ["Any process that modulates the frequency, rate or extent of nodal receptor complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0043949", "l": "regulation of cAMP-mediated signaling", "d": ["Any process which modulates the frequency, rate or extent of cAMP-mediated signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0060271", "l": "cilium assembly", "d": ["The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole."]}, {"i": "REACT:R-HSA-5617833.2", "d": []}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141065", "l": "maternal mRNA clearance", "d": ["The chemical reactions and pathways resulting in the clearance of maternal mRNA transcripts from the zygote as part of the maternal-to-zygote transition in gene expression."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060546", "l": "negative regulation of necroptotic process", "d": ["Any process that decreases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0075001", "l": "adhesion of symbiont infection structure to host", "d": ["The attachment of an infection structure of the symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045316", "l": "negative regulation of compound eye photoreceptor development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001145", "l": "negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0086036", "l": "regulation of cardiac muscle cell membrane potential", "d": ["Any process that modulates the establishment or extent of a membrane potential in a cardiac muscle cell (a cardiomyocyte). A membrane potential is the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099162", "l": "regulation of neurotransmitter loading into synaptic vesicle", "d": ["Any process that modulates the frequency, rate or extent of neurotransmitter loading into synaptic vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0043951", "l": "negative regulation of cAMP-mediated signaling", "d": ["Any process which stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0071029", "l": "nuclear ncRNA surveillance", "d": ["The set of processes involved in identifying and degrading defective or aberrant ncRNAs within the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0001796", "l": "regulation of type IIa hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of type IIa hypersensitivity, a type of inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051214", "l": "RNAi-mediated antiviral immunity against RNA virus", "d": ["An RNAi-mediated post-transcriptional gene silencing pathway induced by RNA viruses leading to a sequence-specific degradation of target mRNAs or inhibition of translation. In plants, DCL4 is the primary Dicer to detect RNA viruses."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0009950", "l": "dorsal/ventral axis specification", "d": ["The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0035883", "l": "enteroendocrine cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044471", "l": "envenomation resulting in pore formation in membrane of another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the aggregation, arrangement and bonding together of a set of components to form a pore complex in a membrane of the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905451", "l": "positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061179", "l": "negative regulation of insulin secretion involved in cellular response to glucose stimulus", "d": ["Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060731", "l": "positive regulation of intestinal epithelial structure maintenance", "d": ["Any process the increases the rate, frequency or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901197", "l": "positive regulation of calcium-mediated signaling involved in cellular response to calcium ion", "d": ["Any positive regulation of calcium-mediated signaling that is involved in cellular response to calcium ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061378", "l": "corpora quadrigemina development", "d": ["The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072035", "l": "pre-tubular aggregate formation", "d": ["The cell adhesion process in which mesenchyme cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098735", "l": "positive regulation of the force of heart contraction", "d": ["Any process that increases the force of heart muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990172", "l": "G protein-coupled receptor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a G protein-coupled receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140723", "l": "patulin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903779", "l": "regulation of cardiac conduction", "d": ["Any process that modulates the frequency, rate or extent of cardiac conduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045458", "l": "recombination within rDNA repeats", "d": ["Genetic recombination within the DNA of the genes coding for ribosomal RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080151", "l": "positive regulation of salicylic acid mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of salicylic acid mediated signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061255", "l": "mesonephric glomerular parietal epithelial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0045840", "l": "positive regulation of mitotic nuclear division", "d": ["Any process that activates or increases the frequency, rate or extent of mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000076", "l": "positive regulation of cytokinesis, site selection", "d": ["Any process that activates or increases the frequency, rate or extent of site selection that occurs as part of cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010425", "l": "DNA methylation on cytosine within a CNG sequence", "d": ["The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within a CNG sequence in a DNA molecule. N stands for any nucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901986", "l": "response to ketamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketamine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902575", "l": "protein localization to cell division site involved in cytokinesis, actomyosin contractile ring assembly", "d": ["Any protein localization to cell division site that is involved in cytokinesis, actomyosin contractile ring assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048455", "l": "stamen formation", "d": ["The process that contributes to the act of giving rise to the stamen. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046252", "l": "toluene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903356", "l": "positive regulation of distal tip cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of distal tip cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035775", "l": "pronephric glomerulus morphogenesis", "d": ["The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0043052", "l": "thermotaxis", "d": ["The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018125", "l": "peptidyl-cysteine methylation", "d": ["The methylation of peptidyl-cysteine to form peptidyl-S-methyl-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.655739316124155", "identifiers": [{"i": "GO:0006721", "l": "terpenoid metabolic process", "d": ["The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0051148", "l": "negative regulation of muscle cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905142", "l": "positive regulation of apical ectodermal ridge formation", "d": ["Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0052322", "l": "positive regulation of phytoalexin biosynthetic process", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062231", "l": "positive regulation of larval somatic muscle development", "d": ["Any process that increases the rate, frequency or extent of larval somatic muscle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060816", "l": "random inactivation of X chromosome", "d": ["Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on either the paternal or maternal X-chromosome in the XX sex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0060351", "l": "cartilage development involved in endochondral bone morphogenesis", "d": ["The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060381", "l": "positive regulation of single-stranded telomeric DNA binding", "d": ["Any process that increases the frequency, rate or extent of single-stranded telomeric DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045602", "l": "negative regulation of endothelial cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.398664172980133", "identifiers": [{"i": "GO:0032984", "l": "protein-containing complex disassembly", "d": ["The disaggregation of a protein-containing macromolecular complex into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900265", "l": "regulation of substance P receptor binding", "d": ["Any process that modulates the frequency, rate or extent of substance P receptor binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060496", "l": "mesenchymal-epithelial cell signaling involved in lung development", "d": ["Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.651613913496419", "identifiers": [{"i": "GO:0061983", "l": "meiosis II cell cycle process", "d": ["A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007341", "l": "penetration of zona pellucida", "d": ["The infiltration by sperm of the zona pellucida to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061052", "l": "negative regulation of cell growth involved in cardiac muscle cell development", "d": ["Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902613", "l": "negative regulation of anti-Mullerian hormone signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anti-Mullerian hormone signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071648", "l": "positive regulation of macrophage inflammatory protein-1 gamma production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902040", "l": "positive regulation of seed dormancy process", "d": ["Any process that activates or increases the frequency, rate or extent of seed dormancy process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001038", "l": "regulation of cellular response to drug", "d": ["Any process that modulates the frequency, rate or extent of cellular response to drug."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070582", "l": "theta DNA replication", "d": ["A DNA-dependent DNA replication process in which a double-stranded DNA molecule is synthesized from a circular duplex template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060031", "l": "mediolateral intercalation", "d": ["The interdigitation of cells along the mediolateral axis during gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900357", "l": "regulation of nigerotriose transport", "d": ["Any process that modulates the frequency, rate or extent of nigerotriose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070667", "l": "negative regulation of mast cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of mast cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1905383", "l": "protein localization to presynapse", "d": ["A process in which a protein is transported to, or maintained in, a location within a presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019916", "l": "peptidyl-D-alanine racemization, direct", "d": ["The racemization of peptidyl-alanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0043302", "l": "positive regulation of leukocyte degranulation", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0006577", "l": "amino-acid betaine metabolic process", "d": ["The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071340", "l": "skeletal muscle acetylcholine-gated channel clustering", "d": ["The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0006040", "l": "amino sugar metabolic process", "d": ["The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070164", "l": "negative regulation of adiponectin secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of adiponectin from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901323", "l": "response to erythromycin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "30.06989093494775", "identifiers": [{"i": "GO:0048513", "l": "animal organ development", "d": ["Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018404", "l": "protein-heparan sulfate linkage via heparan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine", "d": ["Heparan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903402", "l": "regulation of renal phosphate excretion", "d": ["Any process that modulates the frequency, rate or extent of renal phosphate excretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072076", "l": "nephrogenic mesenchyme development", "d": ["The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900022", "l": "regulation of D-erythro-sphingosine kinase activity", "d": ["Any process that modulates the frequency, rate or extent of D-erythro-sphingosine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902408", "l": "mitotic cytokinesis, division site positioning", "d": ["The process in which a contractile ring is positioned in a specific location during the mitotic cell cycle. This process is critical for both for both symmetric and asymmetric cell divisions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0086043", "l": "bundle of His cell action potential", "d": ["An action potential that occurs in a bundle of His cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900683", "l": "regulation of fumonisin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of fumonisin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0051653", "l": "spindle localization", "d": ["Any process in which is the spindle is transported to, and/or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000031", "l": "regulation of salicylic acid mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of salicylic acid mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052649", "l": "coenzyme gamma-F420-2 metabolic process", "d": ["The chemical reactions and pathways involving coenzyme gamma-F420-2 (F420-2; coenzyme F420; N-{N-[O-(7,8-didemethyl-8-hydroxy-5-deazariboflavin phospho)-(S)-lactyl]-gamma-L-glutamyl}-L-glutamate), the amide obtained by formal condensation of the carboxylic acid group of F420-0 with the amino group of L-gamma-glutamyl-L-glutamic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060685", "l": "regulation of prostatic bud formation", "d": ["Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090261", "l": "positive regulation of inclusion body assembly", "d": ["Any process that increases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052777", "l": "diacetylchitobiose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diacetylchitobiose into simpler products."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.825956045430587", "identifiers": [{"i": "GO:0001510", "l": "RNA methylation", "d": ["Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1902110", "l": "positive regulation of mitochondrial membrane permeability involved in apoptotic process", "d": ["Any positive regulation of mitochondrial membrane permeability that is involved in apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902200", "l": "3-methylbut-2-enoyl-CoA(4-) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 3-methylbut-2-enoyl-CoA(4-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120291", "l": "negative regulation of mitotic recombination-dependent replication fork processing", "d": ["Any process that inhibits or decreases the rate of mitotic recombination-dependent replication fork processing. Suppression of recombination at replication forks is necessary to prevent template switching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035399", "l": "helper T cell enhancement of B cell mediated immune response", "d": ["Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051764", "l": "actin crosslink formation", "d": ["The process in which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. The crosslinked filaments may be on the same or differing axes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017055", "l": "negative regulation of RNA polymerase II transcription preinitiation complex assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0150003", "l": "regulation of spontaneous synaptic transmission", "d": ["Any process that modulates the frequency, rate or extent of spontaneous synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902872", "l": "regulation of horizontal cell localization", "d": ["Any process that modulates the frequency, rate or extent of horizontal cell localization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071372", "l": "cellular response to follicle-stimulating hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070079", "l": "histone H4-R3 demethylation", "d": ["The modification of histone H4 by the removal of a methyl group from arginine at position 3 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044320", "l": "cellular response to leptin stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905480", "l": "positive regulation of glutamate-ammonia ligase activity", "d": ["Any process that activates or increases the frequency, rate or extent of glutamate-ammonia ligase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.261443428098588", "identifiers": [{"i": "GO:0061041", "l": "regulation of wound healing", "d": ["Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.570488520511681", "identifiers": [{"i": "GO:0001775", "l": "cell activation", "d": ["A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.967140482697559", "identifiers": [{"i": "GO:0046634", "l": "regulation of alpha-beta T cell activation", "d": ["Any process that modulates the frequency, rate or extent of alpha-beta T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071240", "l": "cellular response to food", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051762", "l": "sesquiterpene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0045732", "l": "positive regulation of protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0016233", "l": "telomere capping", "d": ["A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA. May be mediated by specific single- or double-stranded telomeric DNA binding proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070124", "l": "mitochondrial translational initiation", "d": ["The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150075", "l": "negative regulation of protein-glutamine gamma-glutamyltransferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0016334", "l": "establishment or maintenance of polarity of follicular epithelium", "d": ["Any cellular process that results in the specification, formation or maintenance of a polarized follicular epithelial sheet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0048639", "l": "positive regulation of developmental growth", "d": ["Any process that activates, maintains or increases the rate of developmental growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904887", "l": "Wnt signalosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a Wnt signalosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051557", "l": "leucoanthocyanidin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0005988", "l": "lactose metabolic process", "d": ["The chemical reactions and pathways involving lactose, the disaccharide galactopyranosyl-glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019410", "l": "aerobic respiration, using carbon monoxide as electron donor", "d": ["The metabolic process in which carbon monoxide (CO) is oxidized to carbon dioxide (CO2) to generate energy. Conservation of energy in this process likely uses sodium ion gradients for ATP synthesis and is coupled to quantitative sulfide methylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901506", "l": "regulation of acylglycerol transport", "d": ["Any process that modulates the frequency, rate or extent of acylglycerol transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0015879", "l": "carnitine transport", "d": ["The directed movement of carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900192", "l": "positive regulation of single-species biofilm formation", "d": ["Any process that activates or increases the frequency, rate or extent of single-species biofilm formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000545", "l": "negative regulation of endothelial cell chemotaxis to fibroblast growth factor", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0010016", "l": "shoot system morphogenesis", "d": ["The process in which the anatomical structures of the shoot are generated and organized. The shoot is the part of a seed plant body that is usually above ground."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0032240", "l": "negative regulation of nucleobase-containing compound transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.780700721499244", "identifiers": [{"i": "GO:0043470", "l": "regulation of carbohydrate catabolic process", "d": ["Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902866", "l": "regulation of retina development in camera-type eye", "d": ["Any process that modulates the frequency, rate or extent of retina development in camera-type eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022417", "l": "protein maturation by protein folding", "d": ["The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that results in the attainment of the full functional capacity of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019309", "l": "mannose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0003300", "l": "cardiac muscle hypertrophy", "d": ["The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019050", "l": "suppression by virus of host apoptotic process", "d": ["Any viral process that inhibits apoptosis of infected host cells, facilitating prolonged cell survival during viral replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010804", "l": "negative regulation of tumor necrosis factor-mediated signaling pathway", "d": ["Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000216", "l": "positive regulation of proline metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of proline metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902709", "l": "cellular response to plumbagin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019435", "l": "sophorosyloxydocosanoate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.193892402340154", "identifiers": [{"i": "GO:0120035", "l": "regulation of plasma membrane bounded cell projection organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120214", "l": "negative regulation of histidine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of histidine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003394", "l": "cell adhesion involved in dendrite retrograde extension", "d": ["The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension of a dendrite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902595", "l": "regulation of DNA replication origin binding", "d": ["Any process that modulates the frequency, rate or extent of DNA replication origin binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000608", "l": "positive regulation of cell proliferation involved in mesonephros development", "d": ["Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900633", "l": "pentadecane metabolic process", "d": ["The chemical reactions and pathways involving pentadecane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0090627", "l": "plant epidermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a plant epidermal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033026", "l": "negative regulation of mast cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0015854", "l": "guanine transport", "d": ["The directed movement of guanine, 2-amino-6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904690", "l": "positive regulation of cytoplasmic translational initiation", "d": ["Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.330711238774875", "identifiers": [{"i": "GO:0051129", "l": "negative regulation of cellular component organization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061882", "l": "negative regulation of anterograde axonal transport of mitochondrion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.685364931984026", "identifiers": [{"i": "GO:0030336", "l": "negative regulation of cell migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014056", "l": "regulation of acetylcholine secretion, neurotransmission", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0051153", "l": "regulation of striated muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of striated muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.199731381869285", "identifiers": [{"i": "GO:0010604", "l": "positive regulation of macromolecule metabolic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0120224", "l": "larynx development", "d": ["The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010683", "l": "tricyclic triterpenoid metabolic process", "d": ["The chemical reactions and pathways involving tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060943", "l": "neural crest-derived cardiac fibroblast cell development", "d": ["The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation from a neural crest cell to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090639", "l": "phosphatidylcholine biosynthesis from choline and CDP-diacylglycerol", "d": ["The phosphatidylcholine biosynthetic process that involves a one-step direct condensation of choline with CDP-diacylglycerol to form phosphatidylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.725591100956891", "identifiers": [{"i": "GO:0046849", "l": "bone remodeling", "d": ["The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903605", "l": "cytochrome biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a cytochrome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046334", "l": "octopamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070549", "l": "siRNA-mediated gene silencing by inhibition of translation", "d": ["An siRNA-mediated post-transcriptional gene silencing pathway that blocks the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), an siRNA will typically mediate repression of translation if the siRNA perfectly complements elements located in the 3' untranslated region of target mRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903344", "l": "regulation of protein polyglycylation", "d": ["Any process that modulates the frequency, rate or extent of protein polyglycylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030951", "l": "establishment or maintenance of microtubule cytoskeleton polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032125", "l": "micronucleus organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the micronucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051968", "l": "positive regulation of synaptic transmission, glutamatergic", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003259", "l": "cardioblast anterior-lateral migration", "d": ["The orderly movement of a cardioblast toward the head and laterally to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904829", "l": "regulation of aortic smooth muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006434", "l": "seryl-tRNA aminoacylation", "d": ["The process of coupling serine to seryl-tRNA, catalyzed by seryl-tRNA synthetase. The seryl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a serine-accetping tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905299", "l": "negative regulation of intestinal epithelial cell development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015704", "l": "cyanate transport", "d": ["The directed movement of cyanate, NCO-, the anion of cyanic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0051781", "l": "positive regulation of cell division", "d": ["Any process that activates or increases the frequency, rate or extent of cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0006448", "l": "regulation of translational elongation", "d": ["Any process that modulates the frequency, rate, extent or accuracy of translational elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042443", "l": "phenylethylamine metabolic process", "d": ["The chemical reactions and pathways involving phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904355", "l": "positive regulation of telomere capping", "d": ["Any process that activates or increases the frequency, rate or extent of telomere capping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000814", "l": "positive regulation of barbed-end actin filament capping", "d": ["Any process that activates or increases the frequency, rate or extent of barbed-end actin filament capping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903442", "l": "response to lipoic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903698", "l": "positive regulation of microvillus assembly", "d": ["Any process that activates or increases the frequency, rate or extent of microvillus assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045836", "l": "positive regulation of meiotic nuclear division", "d": ["Any process that activates or increases the frequency, rate or extent of meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903861", "l": "positive regulation of dendrite extension", "d": ["Any process that activates or increases the frequency, rate or extent of dendrite extension."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1904742", "l": "regulation of telomeric DNA binding", "d": ["Any process that modulates the frequency, rate or extent of telomeric DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015677", "l": "copper ion import", "d": ["The directed movement of copper ions into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900936", "l": "negative regulation of nonadec-1-ene biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043330", "l": "response to exogenous dsRNA", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902791", "l": "undecan-2-one biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of undecan-2-one."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0008050", "l": "female courtship behavior", "d": ["The behavior of a female, for the purpose of attracting a sexual partner."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905189", "l": "regulation of metaphase/anaphase transition of meiosis II", "d": ["Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0010459", "l": "negative regulation of heart rate", "d": ["Any process that stops, prevents or reduces the frequency or rate of heart contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006203", "l": "dGTP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903347", "l": "negative regulation of bicellular tight junction assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032668", "l": "regulation of interleukin-24 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-24 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000220", "l": "regulation of pseudohyphal growth", "d": ["Any process that modulates the frequency, rate or extent of pseudohyphal growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061639", "l": "Cdv-dependent cytokinesis", "d": ["A cytokinesis that involves a set of conserved proteins including the Cdv proteins, and results in the formation of two similarly sized and shaped cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075284", "l": "asexual sporulation resulting in formation of a multicellular or syncytial spore", "d": ["The formation of a multicellular or syncytial spore via septations derived from mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140021", "l": "mitochondrial ADP transmembrane transport", "d": ["The process in which ADP is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990218", "l": "positive regulation by symbiont of abscisic acid levels in host", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of the abscisic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090121", "l": "low-density lipoprotein particle disassembly involved in cholesterol transport", "d": ["The disassembly into constituent parts of the low-density lipoprotein particle in the lysosome that contributes to cholesterol transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098907", "l": "regulation of SA node cell action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046016", "l": "positive regulation of transcription by glucose", "d": ["Any process involving glucose that activates or increases the rate of transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070660", "l": "inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration", "d": ["Differentiation of new inner ear sensory hair cells to replace those lost or destroyed by injury."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060157", "l": "urinary bladder development", "d": ["The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0043029", "l": "T cell homeostasis", "d": ["The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904273", "l": "L-alanine import across plasma membrane", "d": ["The directed import of L-alanine from the extracellular region across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0072531", "l": "pyrimidine-containing compound transmembrane transport", "d": ["The process in which a pyrimidine-containing compound is transported across a membrane. A pyrimidine-containing compound is any compound that contains pyrimidine or a formal derivative thereof."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032345", "l": "negative regulation of aldosterone metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090155", "l": "negative regulation of sphingolipid biosynthetic process", "d": ["Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033330", "l": "kaempferol O-glucoside biosynthetic process", "d": ["The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of kaempferol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060913", "l": "cardiac cell fate determination", "d": ["The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000161", "l": "regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052645", "l": "F420-0 metabolic process", "d": ["The chemical reactions and pathways involving F420-0 (5-O-{[(1S)-1-carboxyethoxy](hydroxy)phosphoryl}-1-deoxy-1-(8-hydroxy-2,4-dioxo-2H-pyrimido[4,5-b]quinolin-10(4H)-yl)-D-ribitol), the fragment of coenzyme F420 remaining after formal hydrolytic removal of all of the glutamate residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902919", "l": "poly(5-hydroxyvalerate) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(5-hydroxyvalerate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000835", "l": "negative regulation of androgen secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048578", "l": "positive regulation of long-day photoperiodism, flowering", "d": ["Any process that activates, maintains or increases long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015790", "l": "UDP-xylose transmembrane transport", "d": ["The directed movement of UDP-xylose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.311492862095925", "identifiers": [{"i": "GO:0002262", "l": "myeloid cell homeostasis", "d": ["The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0008355", "l": "olfactory learning", "d": ["Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030840", "l": "negative regulation of intermediate filament polymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament polymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042480", "l": "negative regulation of eye photoreceptor cell development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0061572", "l": "actin filament bundle organization", "d": ["A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0072239", "l": "metanephric glomerulus vasculature development", "d": ["The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901770", "l": "daunorubicin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of daunorubicin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0009590", "l": "detection of gravity", "d": ["The series of events in which a gravitational stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904024", "l": "negative regulation of glucose catabolic process to lactate via pyruvate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to lactate via pyruvate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010710", "l": "regulation of collagen catabolic process", "d": ["Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019615", "l": "catechol catabolic process, ortho-cleavage", "d": ["The chemical reactions and pathways resulting in the breakdown of catechol via the ortho-cleavage pathway, in which the catechol aromatic ring is broken between the two carbon atoms bearing hydroxyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902835", "l": "negative regulation of proline import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of proline import into cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0010911", "l": "regulation of isomerase activity", "d": ["Any process that modulates the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.783030043623796", "identifiers": [{"i": "GO:0048738", "l": "cardiac muscle tissue development", "d": ["The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036225", "l": "cellular response to vitamin B1 starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of vitamin B1 (also called thiamin and thiamine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097510", "l": "base-excision repair, AP site formation via deaminated base removal", "d": ["A base-excision repair, AP site formation process occurring via excision of a deaminated base."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002008", "l": "excitation of vasomotor center by chemoreceptor signaling", "d": ["The process in which the molecular signal from the carotid and aortic bodies is relayed to the vasomotor center, causing it to signal an increase arterial pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021819", "l": "layer formation in cerebral cortex", "d": ["The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905825", "l": "regulation of selenocysteine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of selenocysteine metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000196", "l": "positive regulation of female gonad development", "d": ["Any process that activates or increases the frequency, rate or extent of female gonad development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003048", "l": "regulation of systemic arterial blood pressure by norepinephrine", "d": ["The regulation of blood pressure mediated by the catecholamine signaling molecule norepinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035376", "l": "sterol import", "d": ["The directed movement of a sterol into a cell or organelle. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010899", "l": "regulation of phosphatidylcholine catabolic process", "d": ["Any process that modulates the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905262", "l": "negative regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905353", "l": "ciliary transition fiber assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a ciliary transition fiber."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0072378", "l": "blood coagulation, fibrin clot formation", "d": ["A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903422", "l": "negative regulation of synaptic vesicle recycling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle recycling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061123", "l": "negative regulation of positive chemotaxis to cAMP", "d": ["Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021829", "l": "oligodendrocyte cell migration from the subpallium to the cortex", "d": ["The directed movement of oligodendrocytes from the subpallium to the cerebral cortex during forebrain development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901601", "l": "strigolactone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of strigolactone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033332", "l": "ent-kaurene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ent-kaurene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006604", "l": "phosphoarginine metabolic process", "d": ["The chemical reactions and pathways involving phosphoarginine, a phosphagen of L-arginine with phosphoric acid containing the phosphoamide bond. It is a source of energy in the contraction of muscle in invertebrates, corresponding to phosphocreatine in the muscles of vertebrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097360", "l": "chorionic trophoblast cell proliferation", "d": ["The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090709", "l": "regulation of timing of plant organ formation", "d": ["Any process that modulates the rate, frequency or extent of plant organ formation at a consistent predetermined time point during development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051013", "l": "microtubule severing", "d": ["The process in which a microtubule is broken down into smaller segments. Severing enzymes remove dimers from the middle of the filament to create new ends, unlike depolymerizing kinesins that use ATP to uncap microtubules at their ends."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035045", "l": "sperm plasma membrane disassembly", "d": ["The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990428", "l": "miRNA transport", "d": ["The directed movement of microRNA (miRNA) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044486", "l": "modulation of transmission of nerve impulse in another organism", "d": ["The process in which an organism effects a change in the transmission of a nerve impulse in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0006579", "l": "amino-acid betaine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any betaine, the N-trimethyl derivative of an amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097341", "l": "zymogen inhibition", "d": ["Any process that prevents the proteolytic processing of an inactive enzyme to an active form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901745", "l": "prephenate(2-) metabolic process", "d": ["The chemical reactions and pathways involving prephenate(2-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000715", "l": "nucleotide-excision repair, DNA damage recognition", "d": ["The identification of lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests the repair complex recognizes distortions in the DNA helix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.706877558974412", "identifiers": [{"i": "GO:0045333", "l": "cellular respiration", "d": ["The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0033076", "l": "isoquinoline alkaloid metabolic process", "d": ["The chemical reactions and pathways involving isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140711", "l": "positive regulation of Frizzled Nuclear Import pathway", "d": ["Any process that activates or increases the frequency, rate or extent of a Frizzled Nuclear Import pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000297", "l": "negative regulation of synapse maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synapse maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0055007", "l": "cardiac muscle cell differentiation", "d": ["The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015775", "l": "beta-glucan transport", "d": ["The directed movement of beta-glucans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002280", "l": "monocyte activation involved in immune response", "d": ["The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036049", "l": "peptidyl-lysine desuccinylation", "d": ["The removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue in a peptide or protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001698", "l": "gastrin-induced gastric acid secretion", "d": ["The regulated release of gastric acid induced by the interaction of gastrin with its receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902203", "l": "negative regulation of hepatocyte growth factor receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021690", "l": "cerebellar molecular layer maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046098", "l": "guanine metabolic process", "d": ["The chemical reactions and pathways involving guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043518", "l": "negative regulation of DNA damage response, signal transduction by p53 class mediator", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106397", "l": "positive regulation of R7 cell fate commitment", "d": ["Any process that activates or increases the frequency, rate or extent of R7 cell fate commitment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097500", "l": "receptor localization to non-motile cilium", "d": ["A process in which a receptor is transported to, or maintained in, a location within a non-motile cilium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0001885", "l": "endothelial cell development", "d": ["The progression of an endothelial cell over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905664", "l": "regulation of calcium ion import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0003264", "l": "regulation of cardioblast proliferation", "d": ["Any process that modulates the frequency, rate or extent of cardioblast proliferation. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902156", "l": "positive regulation of response to G1 DNA damage checkpoint signaling", "d": ["Any process that activates or increases the frequency, rate or extent of response to G1 DNA damage checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030886", "l": "negative regulation of myeloid dendritic cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018910", "l": "benzene metabolic process", "d": ["The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901870", "l": "ecgonone methyl ester metabolic process", "d": ["The chemical reactions and pathways involving ecgonone methyl ester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.379321704503681", "identifiers": [{"i": "GO:0009615", "l": "response to virus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019611", "l": "4-toluenecarboxylate metabolic process", "d": ["The chemical reactions and pathways involving 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:1904747", "l": "positive regulation of apoptotic process involved in development", "d": ["Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010147", "l": "fructan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fructan, a polysaccharide consisting of fructose residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070165", "l": "positive regulation of adiponectin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of adiponectin from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060527", "l": "prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis", "d": ["The branching morphogenesis process in which the prostate epithelial cords branch freely to create the structure of the prostate acini."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904367", "l": "positive regulation of chemokinesis", "d": ["Any process that activates or increases the frequency, rate or extent of chemokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035704", "l": "helper T cell chemotaxis", "d": ["The directed movement of a helper T cell in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900087", "l": "positive regulation of G1/S transition of mitotic cell cycle", "d": ["Any signalling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2001316", "l": "kojic acid metabolic process", "d": ["The chemical reactions and pathways involving kojic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0006656", "l": "phosphatidylcholine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072208", "l": "metanephric smooth muscle tissue development", "d": ["The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904687", "l": "positive regulation of mitotic spindle disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic spindle disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0009073", "l": "aromatic amino acid family biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010814", "l": "substance P catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the neuropeptide substance P."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1902151", "l": "regulation of response to DNA integrity checkpoint signaling", "d": ["Any process that modulates the frequency, rate or extent of response to DNA integrity checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0032620", "l": "interleukin-17 production", "d": ["The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000457", "l": "positive regulation of T-helper 17 cell extravasation", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 17 cell extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905674", "l": "regulation of adaptive immune memory response", "d": ["Any process that modulates the frequency, rate or extent of adaptive immune memory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0099039", "l": "sphingolipid translocation", "d": ["The movement of a sphingolipid molecule from one leaflet of a membrane bilayer to the opposite leaflet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072336", "l": "negative regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation", "d": ["Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071353", "l": "cellular response to interleukin-4", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071629", "l": "cytoplasm protein quality control by the ubiquitin-proteasome system", "d": ["The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are targeted to cytoplasmic proteasomes for degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010589", "l": "leaf proximal/distal pattern formation", "d": ["The regionalization process within a leaf by which specific areas of cell differentiation are determined along a proximal/distal axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090375", "l": "negative regulation of transcription from RNA polymerase II promoter in response to iron ion starvation", "d": ["Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031916", "l": "regulation of synaptic metaplasticity", "d": ["A process that modulates synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090034", "l": "regulation of chaperone-mediated protein complex assembly", "d": ["Any process that modulates the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034295", "l": "basidiospore formation", "d": ["The process in which spores form outside a specialized end cell known as a basidium. Basidia are characteristic of the basidiomycete fungi (phylum Basidiomycota), and give rise to spores that each contain a haploid nucleus that is the product of meiosis. The spores are usually attached to the basidium by short spikes called sterigmata (singular: sterigma). In most basidiomycetes there are four sterigmata (and four spores) to a basidium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904875", "l": "regulation of DNA ligase activity", "d": ["Any process that modulates the frequency, rate or extent of DNA ligase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014845", "l": "stomach body smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the body of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990116", "l": "ribosome-associated ubiquitin-dependent protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide encoded by an aberrant message and associated with a stalled ribosome. Degradation is initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the ribosome-associated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034418", "l": "urate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of urate, the anion of uric acid, 2,6,8-trioxypurine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035344", "l": "hypoxanthine transport", "d": ["The directed movement of hypoxanthine, 6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006293", "l": "nucleotide-excision repair, preincision complex stabilization", "d": ["The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060707", "l": "trophoblast giant cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046807", "l": "viral scaffold assembly and maintenance", "d": ["The assembly and maintenance of the viral scaffold around which the viral capsid is constructed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0070977", "l": "bone maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052022", "l": "modulation by symbiont of jasmonic acid levels in host", "d": ["The alteration by an organism of the levels of jasmonic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903641", "l": "positive regulation of gastrin-induced gastric acid secretion", "d": ["Any process that activates or increases the frequency, rate or extent of gastrin-induced gastric acid secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003423", "l": "growth plate cartilage chondrocyte division", "d": ["The process resulting in the oriented physical partitioning and separation of a chondrocytes in the growth plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052104", "l": "induction by symbiont of host systemic acquired resistance", "d": ["Any process in which a symbiont activates systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000884", "l": "glucomannan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a glucomannan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032681", "l": "regulation of lymphotoxin A production", "d": ["Any process that modulates the frequency, rate, or extent of lymphotoxin A production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006047", "l": "UDP-N-acetylglucosamine metabolic process", "d": ["The chemical reactions and pathways involving UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904284", "l": "positive regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I", "d": ["Any process that activates or increases the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019124", "l": "peptidyl-isoleucine racemization", "d": ["The racemization of peptidyl-isoleucine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.586422797268227", "identifiers": [{"i": "GO:0034309", "l": "primary alcohol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901955", "l": "negative regulation of retrograde dense core granule transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060722", "l": "cell proliferation involved in embryonic placenta development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033543", "l": "fatty acid beta-oxidation, unsaturated, even number, reductase/isomerase pathway", "d": ["A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to trans-2-enoyl-CoA by 2,4-dienoyl-CoA reductase and delta3-delta2-enoyl-CoA isomerase; trans-2-enoyl-CoA returns to the core beta-oxidation pathway for further degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0035178", "l": "turning behavior", "d": ["Fine-tuning the spatial position of an organism in response to variability in their environment. For example, reorientation of an organism in the direction of a food source."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003388", "l": "neuron development involved in amphid sensory organ development", "d": ["The process whose specific outcome is the progression of a neuron over time, that contributes to the development of the amphid sensory organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0007129", "l": "homologous chromosome pairing at meiosis", "d": ["The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Homologous chromosome pairing begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0045932", "l": "negative regulation of muscle contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010246", "l": "rhamnogalacturonan I biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of rhamnogalacturonan I component of pectin, a rhamnose-rich pectic polysaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048810", "l": "female analia morphogenesis", "d": ["The process in which the anatomical structures of the analia of the female are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0099150", "l": "regulation of postsynaptic specialization assembly", "d": ["Any process that modulates the frequency, rate or extent of postsynaptic specialization assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010045", "l": "response to nickel cation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel cation stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061544", "l": "peptide secretion, neurotransmission", "d": ["The controlled release of a peptide from a cell in which the peptide acts as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018872", "l": "arsonoacetate metabolic process", "d": ["The chemical reactions and pathways involving arsonoacetate, a synthetic, organic compound containing a single arsenic atom. Arsonoacetate and other arsenic containing compounds are used in agricultural applications as animal feed additives, cotton defoliants and post-emergence grass herbicides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901560", "l": "response to purvalanol A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007110", "l": "meiosis I cytokinesis", "d": ["A cell cycle process that results in the division of the cytoplasm of a cell after meiosis I, resulting in the separation of the original cell into two daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000761", "l": "conjugant formation", "d": ["During conjugation without cellular fusion, the process that results in pairing complementary mating types. Localized morphological, cytological, and cytoskeletal changes connect the mating types without cytoplasmic mixing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0032868", "l": "response to insulin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072268", "l": "pattern specification involved in metanephros development", "d": ["Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.777964009505382", "identifiers": [{"i": "GO:0051702", "l": "biological process involved in interaction with symbiont", "d": ["An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045882", "l": "negative regulation of sulfur utilization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sulfur utilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0043649", "l": "dicarboxylic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035809", "l": "regulation of urine volume", "d": ["Any process that modulates the amount of urine excreted from the body over a unit of time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140077", "l": "positive regulation of lipoprotein transport", "d": ["Any process that activates or increases the rate or extent of lipoprotein transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046000", "l": "positive regulation of ecdysteroid secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of ecdysteroid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0106072", "l": "negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048703", "l": "embryonic viscerocranium morphogenesis", "d": ["The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032100", "l": "positive regulation of appetite", "d": ["Any process that increases appetite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061523", "l": "cilium disassembly", "d": ["A cellular process that results in the breakdown of a cilium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034337", "l": "RNA folding", "d": ["The process of assisting in the covalent and noncovalent assembly of single or multimeric RNAs into the correct tertiary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000240", "l": "positive regulation of tRNA export from nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of tRNA export from nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0016127", "l": "sterol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905885", "l": "positive regulation of triglyceride transport", "d": ["Any process that activates or increases the frequency, rate or extent of triglyceride transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045837", "l": "negative regulation of membrane potential", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031917", "l": "negative regulation of synaptic metaplasticity", "d": ["A process that decreases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034454", "l": "microtubule anchoring at centrosome", "d": ["Any process in which a microtubule is maintained in a specific location in a cell by attachment to a centrosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098677", "l": "virion maturation", "d": ["Maturation of a virion after separation from the host cell. Not all viruses mature after separation. In those that do, maturation typically involves rearangement and/or cleavage of viral proteins, resulting in the virion becoming competent for reinfection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021842", "l": "chemorepulsion involved in interneuron migration from the subpallium to the cortex", "d": ["The creation and reception of signals that result in the movement of interneurons away from the signal during migration from the subpallium to the cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051112", "l": "peptidyl-histidine adenylylation, to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine", "d": ["The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010591", "l": "regulation of lamellipodium assembly", "d": ["Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902288", "l": "regulation of defense response to oomycetes", "d": ["Any process that modulates the frequency, rate or extent of defense response to oomycetes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903183", "l": "negative regulation of SUMO transferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of SUMO ligase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075318", "l": "regulation of ascus development", "d": ["Any process that modulates the frequency, rate or extent of ascus development, a process that leads to the formation of basidium, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0098868", "l": "bone growth", "d": ["The increase in size or mass of a bone that contributes to the shaping of that bone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050939", "l": "regulation of early stripe melanocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of early stripe melanocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075285", "l": "sexual sporulation resulting in formation of a multicellular or syncytial spore", "d": ["The formation of multicellular or syncytial spore via septations derived from meiosis. A multicellular or syncytial spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902781", "l": "cellular response to nonane", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001309", "l": "gliotoxin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060362", "l": "flight involved in flight behavior", "d": ["Self-propelled movement of an organism from one location to another through the air that is part of the organism's response to external or internal stimuli resulting in flight."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140202", "l": "polyamine import across plasma membrane", "d": ["The directed movement of a polyamine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0031946", "l": "regulation of glucocorticoid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019338", "l": "pentachlorophenol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000627", "l": "positive regulation of miRNA catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of miRNA catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000412", "l": "positive regulation of thymocyte migration", "d": ["Any process that activates or increases the frequency, rate or extent of thymocyte migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000739", "l": "regulation of mesenchymal stem cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal stem cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035331", "l": "negative regulation of hippo signaling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039602", "l": "suppression by virus of host transcription initiation from RNA polymerase II promoter", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903885", "l": "negative regulation of chemokine (C-C motif) ligand 20 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-C motif) ligand 20 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110128", "l": "phloem sucrose unloading", "d": ["The process of unloading sucrose that is produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044032", "l": "modulation by symbiont of indole acetic acid levels in host", "d": ["The alteration by an organism of the levels of indole acetic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099546", "l": "protein catabolic process, modulating synaptic transmission", "d": ["Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "29.653313947692489", "identifiers": [{"i": "GO:0009790", "l": "embryo development", "d": ["The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901754", "l": "vitamin D3 catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of vitamin D3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160038", "l": "somatic sensory system development", "d": ["The process whose specific outcome is the progression of a somatic sensory system over time from its formation to the mature structure. Somatic sensory system is the sensory system for the sense of touch and pain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.783030043623796", "identifiers": [{"i": "GO:0002119", "l": "nematode larval development", "d": ["The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051561", "l": "positive regulation of mitochondrial calcium ion concentration", "d": ["Any process that increases the concentration of calcium ions in mitochondria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034137", "l": "positive regulation of toll-like receptor 2 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042997", "l": "negative regulation of Golgi to plasma membrane protein transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010892", "l": "positive regulation of mitochondrial translation in response to stress", "d": ["Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0022617", "l": "extracellular matrix disassembly", "d": ["A process that results in the breakdown of the extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0180002", "l": "renal zinc excretion", "d": ["The elimination of zinc ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048802", "l": "notum morphogenesis", "d": ["The process in which the anatomical structures of the dorsal part of the body are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:2000404", "l": "regulation of T cell migration", "d": ["Any process that modulates the frequency, rate or extent of T cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018246", "l": "protein-coenzyme A linkage", "d": ["The formation of a linkage between a protein amino acid and coenzyme A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042842", "l": "D-xylose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-xylose, a naturally occurring plant polysaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903041", "l": "regulation of chondrocyte hypertrophy", "d": ["Any process that modulates the frequency, rate or extent of chondrocyte hypertrophy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140201", "l": "urea import across plasma membrane", "d": ["The directed movement of urea from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030153", "l": "bacteriocin immunity", "d": ["A process that mediates resistance to a bacteriocin: any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002103", "l": "endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)", "d": ["Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the chloroplasts of vascular plants. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0006312", "l": "mitotic recombination", "d": ["The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous DNA region that occurs during mitotic cell cycles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904382", "l": "mannose trimming involved in glycoprotein ERAD pathway", "d": ["The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0042573", "l": "retinoic acid metabolic process", "d": ["The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031146", "l": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003362", "l": "noradrenergic neuron fate commitment involved in brainstem development", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron that is part of the brainstem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045717", "l": "negative regulation of fatty acid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0045947", "l": "negative regulation of translational initiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007440", "l": "foregut morphogenesis", "d": ["The process in which the anatomical structures of the foregut are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061419", "l": "positive regulation of transcription from RNA polymerase II promoter in response to hypoxia", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003222", "l": "ventricular trabecula myocardium morphogenesis", "d": ["The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060539", "l": "diaphragm development", "d": ["The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0010421", "l": "hydrogen peroxide-mediated programmed cell death", "d": ["Programmed cell death induced by hydrogen peroxide. Programmed cell death is the cell death resulting from activation of endogenous cellular processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0048241", "l": "epinephrine transport", "d": ["The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033085", "l": "negative regulation of T cell differentiation in thymus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0006538", "l": "glutamate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0010951", "l": "negative regulation of endopeptidase activity", "d": ["Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904131", "l": "negative regulation of convergent extension involved in neural plate elongation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in neural plate elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046219", "l": "indolalkylamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0008595", "l": "anterior/posterior axis specification, embryo", "d": ["The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042318", "l": "penicillin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any antibiotic that contains the condensed beta-lactamthiazolidine ring system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900028", "l": "negative regulation of ruffle assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ruffle assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901383", "l": "negative regulation of chorionic trophoblast cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0072677", "l": "eosinophil migration", "d": ["The movement of an eosinophil within or between different tissues and organs of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0044872", "l": "lipoprotein localization", "d": ["Any process in which a lipoprotein is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099047", "l": "clearance of foreign intracellular RNA", "d": ["A defense process that protects an organism from invading foreign RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0045589", "l": "regulation of regulatory T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009848", "l": "indoleacetic acid biosynthetic process via tryptophan", "d": ["The chemical reactions and pathways resulting in the formation of indole-3-acetic acid that occurs through metabolism of L-tryptophan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060866", "l": "leaf abscission", "d": ["The controlled shedding of a leaf."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901023", "l": "4-hydroxyphenylacetate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 4-hydroxyphenylacetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900285", "l": "regulation of cellotriose transport", "d": ["Any process that modulates the frequency, rate or extent of cellotriose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902684", "l": "negative regulation of receptor localization to synapse", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of receptor localization to synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019252", "l": "starch biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of starch, the most important reserve polysaccharide in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.142364941642427", "identifiers": [{"i": "GO:0048568", "l": "embryonic organ development", "d": ["Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002403", "l": "T cell tolerance induction in mucosal-associated lymphoid tissue", "d": ["Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by T cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043703", "l": "photoreceptor cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0002538", "l": "arachidonic acid metabolite production involved in inflammatory response", "d": ["The synthesis or release of products of arachidonic acid metabolism following a stimulus as part of an inflammatory response, resulting in an increase in their intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0008591", "l": "regulation of Wnt signaling pathway, calcium modulating pathway", "d": ["Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0032392", "l": "DNA geometric change", "d": ["The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000228", "l": "positive regulation of pancreatic A cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010366", "l": "negative regulation of ethylene biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of an ethylene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903004", "l": "regulation of protein K63-linked deubiquitination", "d": ["Any process that modulates the frequency, rate or extent of protein K63-linked deubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902185", "l": "positive regulation of shoot apical meristem development", "d": ["Any process that activates or increases the frequency, rate or extent of shoot apical meristem development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000972", "l": "transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery", "d": ["The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery. In S. cerevisiae, this process involves cis-acting DNA sequences such as the TATA box and upstream activating sequence (UAS) elements, trans-acting transcriptional activators, and also the 3'-UTR of the transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1901079", "l": "positive regulation of relaxation of muscle", "d": ["Any process that activates or increases the frequency, rate or extent of relaxation of muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034217", "l": "ascospore wall chitin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032081", "l": "negative regulation of type II site-specific deoxyribonuclease activity", "d": ["Any process that stops or reduces the rate of type II restriction endodeoxyribonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0032799", "l": "low-density lipoprotein receptor particle metabolic process", "d": ["The chemical reactions and pathways involving low-density lipoprotein receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901998", "l": "toxin transport", "d": ["The directed movement of a toxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035069", "l": "larval midgut histolysis", "d": ["The stage-specific break down of the larval midgut during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014880", "l": "regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990171", "l": "SCF complex disassembly in response to cadmium stress", "d": ["The disaggregation of the SCF ubiquitin ligase complex in response to cadmium stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072069", "l": "DCT cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the kidney as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051794", "l": "regulation of timing of catagen", "d": ["Any process that modulates the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070587", "l": "regulation of cell-cell adhesion involved in gastrulation", "d": ["Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018174", "l": "protein-heme P460 linkage", "d": ["The linkage of protein to heme P460."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0016134", "l": "saponin metabolic process", "d": ["The chemical reactions and pathways involving saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0008653", "l": "lipopolysaccharide metabolic process", "d": ["The chemical reactions and pathways involving lipopolysaccharides, a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0034471", "l": "ncRNA 5'-end processing", "d": ["Any process involved in forming the mature 5' end of a non-coding RNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.506234140084757", "identifiers": [{"i": "GO:0023056", "l": "positive regulation of signaling", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of a signaling process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904334", "l": "heme import across plasma membrane", "d": ["The directed movement of heme from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0046950", "l": "cellular ketone body metabolic process", "d": ["The chemical reactions and pathways involving ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone, as carried out by individual cells. Although 3-hydroxybutyrate is not a ketone, it is classed as a ketone body because it exists in an equilibrium with acetoacetate. Ketone bodies may accumulate in excessive amounts in the body in starvation, diabetes mellitus or in other defects of carbohydrate metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070070", "l": "proton-transporting V-type ATPase complex assembly", "d": ["The aggregation, arrangement and bonding together of a proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001151", "l": "regulation of renal water transport", "d": ["Any process that modulates the frequency, rate or extent of renal water transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099502", "l": "calcium-dependent activation of synaptic vesicle fusion", "d": ["The regulatory process by which increased cytosolic calcium levels lead to the the fusion of synaptic vesicles with the presynaptic active zone membrane by bringing primed synaptic vesicle membrane into contact with membrane presynaptic active zone membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140502", "l": "effector-mediated disruption of host salicylic acid-mediated innate immune signalling", "d": ["A process mediated by a molecule secreted by a symbiont that results in the suppression of host salicylic acid-mediated innate immune signalling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032691", "l": "negative regulation of interleukin-1 beta production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010845", "l": "positive regulation of reciprocal meiotic recombination", "d": ["Any process that increases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.961764377177126", "identifiers": [{"i": "GO:0034248", "l": "regulation of amide metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000588", "l": "positive regulation of platelet-derived growth factor receptor-beta signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045982", "l": "negative regulation of purine nucleobase metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving purine nucleobases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018353", "l": "protein-phycocyanobilin linkage via S-phycocyanobilin-L-cysteine", "d": ["The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin via S-phycocyanobilin-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001514", "l": "selenocysteine incorporation", "d": ["The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation; it is not a posttranslational modification of peptidyl-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090313", "l": "regulation of protein targeting to membrane", "d": ["Any process that modulates the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0021604", "l": "cranial nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the cranial nerves. This process pertains to the physical shaping of a rudimentary structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0043324", "l": "pigment metabolic process involved in developmental pigmentation", "d": ["The chemical reactions and pathways involving biological pigments e.g. melanin, occurring as part of the development of an organ or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900950", "l": "regulation of 18-methylnonadec-1-ene biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009257", "l": "10-formyltetrahydrofolate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904222", "l": "positive regulation of serine C-palmitoyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of serine C-palmitoyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0043053", "l": "dauer entry", "d": ["Entry into the facultative diapause of the dauer (enduring) larval stage of nematode development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006433", "l": "prolyl-tRNA aminoacylation", "d": ["The process of coupling proline to prolyl-tRNA, catalyzed by prolyl-tRNA synthetase. The prolyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a methionine-accetping tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0043373", "l": "CD4-positive, alpha-beta T cell lineage commitment", "d": ["The process in which an immature T cell becomes committed to becoming a CD4-positive, alpha-beta T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002076", "l": "osteoblast development", "d": ["The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046033", "l": "AMP metabolic process", "d": ["The chemical reactions and pathways involving AMP, adenosine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009957", "l": "epidermal cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045760", "l": "positive regulation of action potential", "d": ["Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051966", "l": "regulation of synaptic transmission, glutamatergic", "d": ["Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904574", "l": "negative regulation of selenocysteine insertion sequence binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine insertion sequence binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902135", "l": "(+)-secoisolariciresinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (+)-secoisolariciresinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905422", "l": "negative regulation of plant organ morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plant organ morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0001756", "l": "somitogenesis", "d": ["The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0051324", "l": "prophase", "d": ["The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:1902373", "l": "negative regulation of mRNA catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mRNA catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002157", "l": "positive regulation of thyroid hormone mediated signaling pathway", "d": ["Any process that increases the frequency, rate or extent of thyroid hormone mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0033032", "l": "regulation of myeloid cell apoptotic process", "d": ["Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036077", "l": "intratendonous ossification", "d": ["Ossification wherein bone tissue forms within tendonous tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.161881760686384", "identifiers": [{"i": "GO:0002377", "l": "immunoglobulin production", "d": ["The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902563", "l": "regulation of neutrophil activation", "d": ["Any process that modulates the frequency, rate or extent of neutrophil activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048769", "l": "sarcomerogenesis", "d": ["The process in which sarcomeres are added in series within a fiber."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990852", "l": "protein transport along microtubule to spindle pole body", "d": ["The directed movement of a protein along a microtubule to the spindle pole body, mediated by motor proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034201", "l": "response to oleic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106128", "l": "negative regulation of store-operated calcium entry", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium entry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000657", "l": "negative regulation of apolipoprotein binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051571", "l": "positive regulation of histone H3-K4 methylation", "d": ["Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0030178", "l": "negative regulation of Wnt signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0050919", "l": "negative chemotaxis", "d": ["The directed movement of a motile cell or organism towards a lower concentration of a chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034383", "l": "low-density lipoprotein particle clearance", "d": ["The process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:1905359", "l": "protein localization to meiotic spindle", "d": ["A process in which a protein is transported to, or maintained in, a location within a meiotic spindle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.481944844857608", "identifiers": [{"i": "GO:0007623", "l": "circadian rhythm", "d": ["Any biological process in an organism that recurs with a regularity of approximately 24 hours."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900580", "l": "(17Z)-protosta-17(20),24-dien-3beta-ol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (17Z)-protosta-17(20),24-dien-3beta-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.240853996207278", "identifiers": [{"i": "GO:0198738", "l": "cell-cell signaling by wnt", "d": ["Any process that mediates the transfer of information from one cell to another, medaited by a wnt family protein ligand. This process includes wnt signal transduction in the receiving cell, release of wnt ligand from a secreting cell as well as any processes that actively facilitate wnt transport and presentation to receptor on the recieving cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048294", "l": "negative regulation of isotype switching to IgE isotypes", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.411753859901495", "identifiers": [{"i": "GO:0051937", "l": "catecholamine transport", "d": ["The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010373", "l": "negative regulation of gibberellin biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903688", "l": "positive regulation of border follicle cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of border follicle cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097707", "l": "ferroptosis", "d": ["A programmed cell death characterized morphologically by the presence of smaller than normal mitochondria with condensed mitochondrial membrane densities, reduction or vanishing of mitochondria crista, and outer mitochondrial membrane rupture. Activation of mitochondrial voltage-dependent anion channels and mitogen-activated protein kinases, upregulation of endoplasmic reticulum stress, and inhibition of cystine/glutamate antiporter are involved in the induction of ferroptosis. This process is characterized by the accumulation of lipid peroxidation products and lethal reactive oxygen species (ROS) derived from iron metabolism. Glutathione peroxidase 4 (GPX4), heat shock protein beta-1, and nuclear factor erythroid 2-related factor 2 function as negative regulators of ferroptosis by limiting ROS production and reducing cellular iron uptake, respectively. In contrast, NADPH oxidase and p53 act as positive regulators of ferroptosis by promotion of ROS production and inhibition of expression of SLC7A11 (a specific light-chain subunit of the cystine/glutamate antiporter), respectively. Misregulated ferroptosis has been implicated in multiple physiological and pathological processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048929", "l": "efferent axon development in posterior lateral line nerve", "d": ["The process whose specific outcome is the progression of an efferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the posterior lateral line nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0097206", "l": "nephrocyte filtration", "d": ["The process by which hemolymph is filtered based on size and charge through a nephrocyte filtration barrier formed by the basement membrane and nephrocyte diaphragm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902499", "l": "positive regulation of protein autoubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein autoubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902235", "l": "regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.415093686714229", "identifiers": [{"i": "GO:0051341", "l": "regulation of oxidoreductase activity", "d": ["Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006741", "l": "NADP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; biosynthesis may be of either the oxidized form, NADP, or the reduced form, NADPH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071267", "l": "L-methionine salvage", "d": ["Any process that generates L-methionine from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902172", "l": "regulation of keratinocyte apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009602", "l": "detection of symbiont", "d": ["The series of events in which a stimulus from a symbiont (an organism living in close physical association with an organism of a different species) is received and converted into a molecular signal. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046368", "l": "GDP-L-fucose metabolic process", "d": ["The chemical reactions and pathways involving GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090073", "l": "positive regulation of protein homodimerization activity", "d": ["Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036365", "l": "transforming growth factor beta2 activation", "d": ["The release of transforming growth factor beta 2 (TGF-beta2) from its latent state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090336", "l": "positive regulation of brown fat cell differentiation", "d": ["Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120007", "l": "negative regulation of glutamatergic neuron differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021600", "l": "abducens nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the abducens nerve. This process pertains to the physical shaping of a rudimentary structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0036475", "l": "neuron death in response to oxidative stress", "d": ["Any biological process that results in permanent cessation of all vital functions of a neuron upon exposure to an oxidative stress stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.124646994401843", "identifiers": [{"i": "GO:0048569", "l": "post-embryonic animal organ development", "d": ["Development, taking place during the post-embryonic phase of an animal tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0036466", "l": "synaptic vesicle recycling via endosome", "d": ["Synaptic vesicle recycling where vesicles endocytosed via clathrin-coated pits re-acidify and refill with neurotransmitters after passing through an endosomal intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010795", "l": "regulation of ubiquinone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of ubiquinone biosynthesis. Ubiquinone biosynthesis consists of the chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0061062", "l": "regulation of nematode larval development", "d": ["Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904395", "l": "positive regulation of skeletal muscle acetylcholine-gated channel clustering", "d": ["Any process that activates or increases the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.435677177067305", "identifiers": [{"i": "GO:0007389", "l": "pattern specification process", "d": ["Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002240", "l": "response to molecule of oomycetes origin", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052092", "l": "positive regulation of nutrient release by host", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071503", "l": "response to heparin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0006924", "l": "activation-induced cell death of T cells", "d": ["A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0043247", "l": "telomere maintenance in response to DNA damage", "d": ["Any process that occur in response to the presence of critically short or damaged telomeres."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904908", "l": "negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1904519", "l": "protein localization to microtubule minus-end", "d": ["A process in which a protein is transported to, or maintained in, a location at a microtubule minus-end."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070318", "l": "positive regulation of G0 to G1 transition", "d": ["A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1902108", "l": "regulation of mitochondrial membrane permeability involved in apoptotic process", "d": ["Any regulation of mitochondrial membrane permeability that is involved in apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090380", "l": "seed trichome maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a seed trichome to attain its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018082", "l": "peptidyl-(Z)-dehydrobutyrine biosynthetic process from peptidyl-threonine", "d": ["The formation of (Z)-dehydrobutyrine by the dehydration of peptidyl-threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000844", "l": "negative regulation of testosterone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032246", "l": "regulation of pyrimidine nucleoside transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a pyrimidine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048577", "l": "negative regulation of short-day photoperiodism, flowering", "d": ["Any process that stops, prevents or reduces short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:0072528", "l": "pyrimidine-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046001", "l": "negative regulation of preblastoderm mitotic cell cycle", "d": ["Any process that stops, prevents or reduces the rate or extent of progression through the preblastoderm mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003414", "l": "chondrocyte morphogenesis involved in endochondral bone morphogenesis", "d": ["The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000067", "l": "regulation of root morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of root morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016268", "l": "O-glycan processing, core 2", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 2 O-glycan structure, GlcNAc-beta-(1->6)[Gal-beta-(1->3)]-GalNAc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045652", "l": "regulation of megakaryocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of megakaryocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0046352", "l": "disaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of disaccharides, sugars composed of two monosaccharide units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018132", "l": "peptide cross-linking via L-cysteine oxazolecarboxylic acid", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0035305", "l": "negative regulation of dephosphorylation", "d": ["Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0001834", "l": "trophectodermal cell proliferation", "d": ["The proliferation of cells in the trophectoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1904732", "l": "regulation of electron transfer activity", "d": ["Any process that modulates the frequency, rate or extent of electron transfer activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990670", "l": "vesicle fusion with Golgi cis cisterna membrane", "d": ["The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi cis cisterna. This can involve anterograde or retrograde transport vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140194", "l": "negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044719", "l": "regulation of imaginal disc-derived wing size", "d": ["Any process that modulates the size of an imaginal disc-derived wing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031157", "l": "regulation of aggregate size involved in sorocarp development", "d": ["Any process that modulates the size of the aggregate formed during sorocarp formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902608", "l": "positive regulation of large conductance calcium-activated potassium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of large conductance calcium-activated potassium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900544", "l": "positive regulation of purine nucleotide metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901199", "l": "positive regulation of calcium ion transport into cytosol involved in cellular response to salt stress", "d": ["Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046927", "l": "peptidyl-threonine racemization", "d": ["The racemization of peptidyl-L-threo-threonine at the alpha-carbon to form D-allo-threonine. This is coupled with the formation of the cross-link 2-(S-L-cysteinyl)-D-allo-threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032815", "l": "negative regulation of natural killer cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046487", "l": "glyoxylate metabolic process", "d": ["The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021525", "l": "lateral motor column neuron differentiation", "d": ["The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of lateral motor column neurons. Lateral motor column neurons are generated only on limb levels and send axons into the limb mesenchyme. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002412", "l": "antigen transcytosis by M cells in mucosal-associated lymphoid tissue", "d": ["The process of antigen transcytosis carried out by M cells in the mucosal-associated lymphoid tissue (MALT). Transcytosis is the process of the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. M cells are specialized epithelia cells with a microfold structure that are adept at moving antigens from the gut lumen to antigen presenting cells in the MALT."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903412", "l": "response to bile acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030885", "l": "regulation of myeloid dendritic cell activation", "d": ["Any process that modulates the frequency or rate of myeloid dendritic cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0008292", "l": "acetylcholine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0001113", "l": "transcription open complex formation at RNA polymerase II promoter", "d": ["Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072253", "l": "metanephric juxtaglomerulus cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric juxtaglomerulus cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033145", "l": "positive regulation of intracellular steroid hormone receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0055002", "l": "striated muscle cell development", "d": ["The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034374", "l": "low-density lipoprotein particle remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048227", "l": "plasma membrane to endosome transport", "d": ["Transport of a vesicle from the plasma membrane to the endosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904436", "l": "negative regulation of transferrin receptor binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transferrin receptor binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0032075", "l": "positive regulation of nuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045346", "l": "regulation of MHC class II biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902421", "l": "hydrogen metabolic process", "d": ["The chemical reactions and pathways involving H2 (dihydrogen)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098822", "l": "peptidyl-cysteine modification to L-cysteine persulfide", "d": ["The modification of peptidyl-cysteine to form peptidyl-L-cysteine persulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903497", "l": "cellular response to 11-deoxycorticosterone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902784", "l": "response to undecane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "43.009136810615992", "identifiers": [{"i": "GO:0055085", "l": "transmembrane transport", "d": ["The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030910", "l": "olfactory placode formation", "d": ["The formation of a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036076", "l": "ligamentous ossification", "d": ["Ossification wherein bone tissue forms within ligamentous tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051280", "l": "negative regulation of release of sequestered calcium ion into cytosol", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060608", "l": "cell-cell adhesion involved in neural tube closure", "d": ["The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034476", "l": "U5 snRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a U5 snRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000963", "l": "regulation of cellooligosaccharide catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellooligosaccharide catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072476", "l": "response to mitotic spindle checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of mitotic cell cycle spindle checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021658", "l": "rhombomere 3 morphogenesis", "d": ["The process in which the anatomical structure of rhombomere 3 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0039506", "l": "modulation by virus of host molecular function", "d": ["The process in which a virus effects a change in the function of a host protein via a direct interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901613", "l": "negative regulation of terminal button organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of terminal button organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900323", "l": "positive regulation of maltotetraose transport", "d": ["Any process that activates or increases the frequency, rate or extent of maltotetraose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033688", "l": "regulation of osteoblast proliferation", "d": ["Any process that modulates the frequency, rate or extent of osteoblast proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.468544520863134", "identifiers": [{"i": "GO:0048332", "l": "mesoderm morphogenesis", "d": ["The process in which the anatomical structures of the mesoderm are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061185", "l": "negative regulation of dermatome development", "d": ["Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015710", "l": "tellurite transport", "d": ["The directed movement of tellurite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0044539", "l": "long-chain fatty acid import into cell", "d": ["The directed movement of a long-chain fatty acid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046076", "l": "dTTP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dTTP, deoxyribosylthymine triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051395", "l": "negative regulation of nerve growth factor receptor activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106230", "l": "protein depropionylation", "d": ["The removal of a propionyl group from a residue in a peptide or protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009560", "l": "embryo sac egg cell differentiation", "d": ["The process in which an uncellularized embryo sac nucleus cellularizes and acquires the specialized features of an egg cell. An example of this process is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.139845358389962", "identifiers": [{"i": "GO:1901136", "l": "carbohydrate derivative catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904647", "l": "response to rotenone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0075713", "l": "establishment of integrated proviral latency", "d": ["A process by which the virus integrates into the host genome and establishes as a stable provirus or prophage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060323", "l": "head morphogenesis", "d": ["The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0050826", "l": "response to freezing", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900199", "l": "positive regulation of protein export from nucleus during meiotic anaphase II", "d": ["Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm, during anaphase occurring as part of meiosis II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141017", "l": "effector-mediated induction of cell cycle reactivation in host", "d": ["A symbiont process in which a molecule secreted by the symbiont reactivates the host cell cycle, resulting in DNA synthesis and host cell division, and contributing to vegetative tumor formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0071941", "l": "nitrogen cycle metabolic process", "d": ["A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902021", "l": "regulation of bacterial-type flagellum-dependent cell motility", "d": ["Any process that modulates the frequency, rate or extent of bacterial-type flagellum-dependent cell motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0045601", "l": "regulation of endothelial cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of endothelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0036395", "l": "pancreatic amylase secretion", "d": ["The controlled release of amylase from a cell of the pancreas."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060081", "l": "membrane hyperpolarization", "d": ["The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090327", "l": "negative regulation of locomotion involved in locomotory behavior", "d": ["Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010707", "l": "globoside biosynthetic process via lactosylceramide", "d": ["The chemical reactions and pathways resulting in the formation of globosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035824", "l": "long tract gene conversion", "d": ["A gene conversion process in which a segment of more than 1000 base pairs is transferred from the donor to the acceptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140157", "l": "ammonium import across plasma membrane", "d": ["The directed movement of an ammonium ion from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904699", "l": "positive regulation of acinar cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of acinar cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002721", "l": "regulation of B cell cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of B cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021941", "l": "negative regulation of cerebellar granule cell precursor proliferation", "d": ["The process that stops, prevents or reduces the rate or extent of granule cell precursor proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046049", "l": "UMP metabolic process", "d": ["The chemical reactions and pathways involving UMP, uridine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904709", "l": "negative regulation of granulosa cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904571", "l": "positive regulation of selenocysteine incorporation", "d": ["Any process that activates or increases the frequency, rate or extent of selenocysteine incorporation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0061113", "l": "pancreas morphogenesis", "d": ["Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001288", "l": "positive regulation of caveolin-mediated endocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of caveolin-mediated endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110005", "l": "positive regulation of tRNA C5-cytosine methylation", "d": ["Any process that activates or increases the frequency, rate or extent of tRNA C5-cytosine methylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070351", "l": "negative regulation of white fat cell proliferation", "d": ["Any process that stops or decreases the rate or extent of white fat cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051574", "l": "positive regulation of histone H3-K9 methylation", "d": ["Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901344", "l": "response to leptomycin B", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014025", "l": "neural keel formation", "d": ["The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021698", "l": "cerebellar cortex structural organization", "d": ["The process that contributes to the act of creating the structural organization of the cerebellar cortex. This process pertains to the physical shaping of a rudimentary structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035365", "l": "regulation of thymine transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902228", "l": "positive regulation of macrophage colony-stimulating factor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0010977", "l": "negative regulation of neuron projection development", "d": ["Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060836", "l": "lymphatic endothelial cell differentiation", "d": ["The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002050", "l": "pyoverdine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the siderochrome pyoverdine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006285", "l": "base-excision repair, AP site formation", "d": ["The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150189", "l": "regulation of interleukin-32 production", "d": ["Any process that modulates the frequency, rate or extent of interleukin-32 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0045634", "l": "regulation of melanocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of melanocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035136", "l": "forelimb morphogenesis", "d": ["The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0030212", "l": "hyaluronan metabolic process", "d": ["The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044069", "l": "modulation by symbiont of host anion transport", "d": ["The process in which a symbiont organism modulates the anion transport, the directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, of its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901169", "l": "3-chlorocatechol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 3-chlorocatechol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070476", "l": "rRNA (guanine-N7)-methylation", "d": ["The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060461", "l": "right lung morphogenesis", "d": ["The process in which anatomical structures of the right lung are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034167", "l": "regulation of toll-like receptor 10 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 10 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904980", "l": "positive regulation of endosome organization", "d": ["Any process that activates or increases the frequency, rate or extent of endosome organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0035234", "l": "ectopic germ cell programmed cell death", "d": ["Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097336", "l": "response to risperidone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a risperidone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097377", "l": "spinal cord interneuron axon guidance", "d": ["The process in which the migration of an axon growth cone of a spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal cord interneuron is a CNS interneuron located in the spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902909", "l": "negative regulation of melanosome transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of melanosome transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045588", "l": "positive regulation of gamma-delta T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0071676", "l": "negative regulation of mononuclear cell migration", "d": ["Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021860", "l": "pyramidal neuron development", "d": ["The progression of a pyramidal neuron from its initial formation to its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072756", "l": "cellular response to paraquat", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904819", "l": "parietal peritoneum development", "d": ["The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048078", "l": "positive regulation of compound eye pigmentation", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the compound eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060708", "l": "spongiotrophoblast differentiation", "d": ["The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003358", "l": "noradrenergic neuron development", "d": ["The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018895", "l": "dibenzothiophene metabolic process", "d": ["The chemical reactions and pathways involving dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond. Dibenzothiophene derivatives can be detected in diesel oil following hydrodesulfurization treatment to remove sulfur compounds that would otherwise generate sulfur oxides during combustion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0090559", "l": "regulation of membrane permeability", "d": ["Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080180", "l": "2-methylguanosine metabolic process", "d": ["The chemical reactions and pathways involving 2-methylguanosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902916", "l": "positive regulation of protein polyubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein polyubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903966", "l": "monounsaturated fatty acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monounsaturated fatty acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002897", "l": "positive regulation of central B cell tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of central B cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045819", "l": "positive regulation of glycogen catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070247", "l": "regulation of natural killer cell apoptotic process", "d": ["Any process that modulates the occurrence or rate of natural killer cell death by apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031162", "l": "sulfur incorporation into metallo-sulfur cluster", "d": ["The incorporation of exogenous sulfur into a metallo-sulfur cluster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042251", "l": "maintenance of polarity of larval imaginal disc epithelium", "d": ["The maintenance of an established polarized larval imaginal disc epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019643", "l": "reductive tricarboxylic acid cycle", "d": ["A pathway leading to the fixation of two molecules of CO2 and the production of one molecule of acetyl-CoA; essentially the oxidative TCA cycle running in reverse. Acetyl-CoA is reductively carboxylated to pyruvate, from which all other central metabolites can be formed. Most of the enzymes of reductive and oxidative TCA cycle are shared, with the exception of three key enzymes that allow the cycle to run in reverse: ATP citrate lyase, 2-oxoglutarate:ferredoxin oxidoreductase, and fumarate reductase. 2-oxoglutarate:ferredoxin oxidoreductase catalyzes the carboxylation of succinyl-CoA to 2-oxoglutarate, ATP citrate lyase the ATP-dependent cleavage of citrate to acetyl-CoA and oxaloacetate, and fumarate reductase the reduction of fumarate forming succinate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071464", "l": "cellular response to hydrostatic pressure", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080179", "l": "1-methylguanosine metabolic process", "d": ["The chemical reactions and pathways involving 1-methylguanosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010752", "l": "regulation of cGMP-mediated signaling", "d": ["Any process that modulates the rate, frequency or extent of cGMP-mediated signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015687", "l": "ferric-hydroxamate import into cell", "d": ["A process in which ferric-hydroxamate, the iron-bound form of the iron chelator hydroxamate, is transported into the cell by specific cell surface receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097325", "l": "melanocyte proliferation", "d": ["The multiplication or reproduction of melanocytes, resulting in the expansion of a cell population. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902995", "l": "positive regulation of phospholipid efflux", "d": ["Any process that activates or increases the frequency, rate or extent of phospholipid efflux."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:1904950", "l": "negative regulation of establishment of protein localization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.419918338532511", "identifiers": [{"i": "GO:0002684", "l": "positive regulation of immune system process", "d": ["Any process that activates or increases the frequency, rate, or extent of an immune system process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046002", "l": "positive regulation of preblastoderm mitotic cell cycle", "d": ["Any process that activates or increases the rate or extent of progression through the preblastoderm mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002126", "l": "instrumental aggressive behavior", "d": ["Aggressive behavior directed towards obtaining some goal, considered to be a learned response to a situation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106082", "l": "sucrose import across plasma membrane", "d": ["The directed movement of sucrose from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070641", "l": "vitamin D4 metabolic process", "d": ["The chemical reactions and pathways involving vitamin D4, (3S,5Z,7E)-9,10-secoergosta-5,7,10(19)-trien-3-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007348", "l": "regulation of syncytial blastoderm mitotic cell cycle", "d": ["A cell cycle process that modulates the rate or extent of the progression through the syncytial blastoderm mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060389", "l": "pathway-restricted SMAD protein phosphorylation", "d": ["The process of introducing a phosphate group on to a pathway restricted SMAD protein. A pathway restricted SMAD protein is an effector protein that acts directly downstream of the transforming growth factor family receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.777964009505382", "identifiers": [{"i": "GO:0052031", "l": "modulation by symbiont of host defense response", "d": ["Any process in which an organism modulates the frequency, rate or extent of the defense response of its host, the response mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904255", "l": "negative regulation of iron ion transmembrane transporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an iron transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904074", "l": "negative regulation of trophectodermal cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097704", "l": "cellular response to oscillatory fluid shear stress", "d": ["Any response to oscillatory fluid shear stress that occurs at the level of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034231", "l": "islet amyloid polypeptide processing", "d": ["The formation of mature islet amyloid polypeptide (IAPP) by posttranslational processing of pro-islet amyloid polypeptide (pro-IAPP)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.116918913335823", "identifiers": [{"i": "GO:0005984", "l": "disaccharide metabolic process", "d": ["The chemical reactions and pathways involving any disaccharide, sugars composed of two monosaccharide units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060149", "l": "negative regulation of post-transcriptional gene silencing", "d": ["Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000715", "l": "regulation of maintenance of mitotic sister chromatid cohesion, arms", "d": ["Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048893", "l": "afferent axon development in lateral line nerve", "d": ["The process whose specific outcome is the progression of an afferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in any lateral line nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.876036511014462", "identifiers": [{"i": "GO:0003018", "l": "vascular process in circulatory system", "d": ["A circulatory process that occurs at the level of the vasculature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035163", "l": "embryonic hemocyte differentiation", "d": ["The process in which a relatively unspecialized cell derived from the embryonic head mesoderm acquires the specialized features of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0035372", "l": "protein localization to microtubule", "d": ["A process in which a protein is transported to, or maintained at, a microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048254", "l": "snoRNA localization", "d": ["Any process in which small nucleolar RNA is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:2000134", "l": "negative regulation of G1/S transition of mitotic cell cycle", "d": ["Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043328", "l": "protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "d": ["The process of directing proteins towards the vacuole that contributes to protein catabolism via the multivesicular body (MVB) pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900549", "l": "N',N'',N'''-triacetylfusarinine C metabolic process", "d": ["The chemical reactions and pathways involving N',N'',N'''-triacetylfusarinine C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071277", "l": "cellular response to calcium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0018157", "l": "peptide cross-linking via an oxazole or thiazole", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine, or peptidyl cysteine-peptidyl glycine cross-link by the condensation of the serine hydroxyl or cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905084", "l": "positive regulation of mitochondrial translational elongation", "d": ["Any process that activates or increases the frequency, rate or extent of mitochondrial translational elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090096", "l": "positive regulation of metanephric cap mesenchymal cell proliferation", "d": ["Any process that increases the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0006739", "l": "NADP metabolic process", "d": ["The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060503", "l": "bud dilation involved in lung branching", "d": ["The process in which a bud in the lung increases radially."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0032780", "l": "negative regulation of ATP-dependent activity", "d": ["Any process that stops or reduces the rate of an ATP-dependent activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098841", "l": "protein localization to cell division site after cytokinesis", "d": ["A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division following cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090176", "l": "microtubule cytoskeleton organization involved in establishment of planar polarity", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins and contributes to the establishment of planar polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903638", "l": "positive regulation of protein insertion into mitochondrial outer membrane", "d": ["Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial outer membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030846", "l": "termination of RNA polymerase II transcription, poly(A)-coupled", "d": ["An RNA polymerase II transcription termination process in which cleavage and polyadenylylation of the mRNA 3' end are coupled to transcription termination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903259", "l": "exon-exon junction complex disassembly", "d": ["The disaggregation of an exon-exon junction complex into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0010232", "l": "vascular transport", "d": ["The directed movement of substances, into, out of or within a cell, either in a vascular tissue or in the vascular membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075526", "l": "cap snatching", "d": ["A transcription initiation process during which a nucleotide sequence between 10 and 20 nucleotides in size is cleaved from the 5' end of host mRNAs by a viral RNA-dependent polymerase. The capped leader sequence obtained is subsequently used to prime transcription on the viral genome, which ultimately leads to the synthesis of capped, translatable viral mRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904314", "l": "cellular response to methamphetamine hydrochloride", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.116918913335823", "identifiers": [{"i": "GO:0072164", "l": "mesonephric tubule development", "d": ["The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010128", "l": "benzoate catabolic process via CoA ligation", "d": ["The chemical reactions and pathways resulting in the breakdown of benzoate, by its ligation to Coenzyme A to form benzoyl-CoA, which is then broken by an aerobic or anaerobic pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046986", "l": "negative regulation of hemoglobin biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044739", "l": "positive regulation of acid-sensing ion channel in another organism", "d": ["Any process in which an organism positively regulates the activity of a voltage-gated sodium channel in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160060", "l": "sleep homeostasis", "d": ["A homeostatic process in which the drive for sleep increases sleep propensity with prolonged wakefulness."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051490", "l": "negative regulation of filopodium assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007489", "l": "maintenance of imaginal histoblast diploidy", "d": ["The negative regulation of the differentiation of polytenized larval hypodermal cells from abdominal histoblasts. The abdominal histoblasts remain a small cluster of diploid cells among the polytenized larval hypodermal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903914", "l": "negative regulation of fusion of virus membrane with host plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fusion of virus membrane with host plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009724", "l": "detection of abscisic acid stimulus", "d": ["The series of events in which an abscisic acid stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902422", "l": "hydrogen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of H2 (dihydrogen)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900259", "l": "regulation of RNA-dependent RNA polymerase activity", "d": ["Any process that modulates the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002512", "l": "central T cell tolerance induction", "d": ["Tolerance induction of T cells in the thymus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031945", "l": "positive regulation of glucocorticoid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071042", "l": "nuclear polyadenylation-dependent mRNA catabolic process", "d": ["The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0072243", "l": "metanephric nephron epithelium development", "d": ["The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000876", "l": "positive regulation of glyoxylate cycle", "d": ["Any process that activates or increases the frequency, rate or extent of glyoxylate cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019271", "l": "aerobactin transport", "d": ["The directed movement of the hydroxamate iron transport compound aerobactin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aerobactin (C22H36N4O13) is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1902175", "l": "regulation of oxidative stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000850", "l": "negative regulation of glucocorticoid secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039704", "l": "viral translational shunt", "d": ["A viral translation initiation mechanism where ribosomes are loaded onto viral mRNA at the 5'-cap structure and start scanning for a short distance before by-passing the large internal leader region and initiating at a downstream start site."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018002", "l": "N-terminal peptidyl-glutamic acid acetylation", "d": ["The acetylation of the N-terminal glutamic acid of proteins to form the derivate acetyl-glutamic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035970", "l": "peptidyl-threonine dephosphorylation", "d": ["The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048371", "l": "lateral mesodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a lateral mesoderm cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060151", "l": "peroxisome localization", "d": ["Any process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0075317", "l": "ascus development", "d": ["The process that leads to the development of ascus, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0046209", "l": "nitric oxide metabolic process", "d": ["The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0035168", "l": "larval lymph gland hemocyte differentiation", "d": ["The process in which a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000979", "l": "positive regulation of forebrain neuron differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0048048", "l": "embryonic eye morphogenesis", "d": ["The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060873", "l": "anterior semicircular canal development", "d": ["The progession of the anterior semicircular canal from its initial formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007138", "l": "meiotic anaphase II", "d": ["The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0021801", "l": "cerebral cortex radial glia-guided migration", "d": ["The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0010632", "l": "regulation of epithelial cell migration", "d": ["Any process that modulates the frequency, rate or extent of epithelial cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0030042", "l": "actin filament depolymerization", "d": ["Disassembly of actin filaments by the removal of actin monomers from a filament."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141025", "l": "adhesion of symbiont to host cell surface via host glycoprotein", "d": ["The attachment of a symbiont to its host by binding to a glycoprotein on the host cell surface. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090108", "l": "positive regulation of high-density lipoprotein particle assembly", "d": ["Any process that increases the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045755", "l": "negative regulation of initiation of acetate catabolic process by acetate", "d": ["Any process that stops or prevents the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0036093", "l": "germ cell proliferation", "d": ["The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901254", "l": "positive regulation of intracellular transport of viral material", "d": ["Any process that activates or increases the frequency, rate or extent of intracellular transport of viral material."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009811", "l": "stilbene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001005", "l": "positive regulation of pectin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of pectin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042376", "l": "phylloquinone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010070", "l": "zygote asymmetric cell division", "d": ["The division of the zygote into two daughter cells that will adopt developmentally distinct potentials."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0043694", "l": "monoterpene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of monoterpenes, terpenes with a C10 structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002012", "l": "vasoconstriction of artery involved in chemoreceptor response to lowering of systemic arterial blood pressure", "d": ["A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050653", "l": "chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process", "d": ["The elongation of chondroitin sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of chondroitin sulfate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090149", "l": "mitochondrial membrane fission", "d": ["A process that is carried out at the cellular level which results in the separation of a single continuous mitochondrial membrane into two membranes and contributes to mitochondrial fission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903101", "l": "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019064", "l": "fusion of virus membrane with host plasma membrane", "d": ["Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0016075", "l": "rRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural constituent of ribosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009650", "l": "UV protection", "d": ["Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072482", "l": "response to mitotic cell cycle spindle orientation checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of mitotic cell cycle spindle orientation checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901131", "l": "kanamycin metabolic process", "d": ["The chemical reactions and pathways involving kanamycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021591", "l": "ventricular system development", "d": ["The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1990399", "l": "epithelium regeneration", "d": ["The regrowth of lost or destroyed epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010235", "l": "guard mother cell cytokinesis", "d": ["The stereotyped symmetric cell division by which guard mother cell give rise to stomatal guard cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071721", "l": "sodium-independent thromboxane transport", "d": ["The directed, sodium-independent, movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.805366613539277", "identifiers": [{"i": "GO:0060350", "l": "endochondral bone morphogenesis", "d": ["The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904817", "l": "serous membrane development", "d": ["The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905749", "l": "regulation of endosome to plasma membrane protein transport", "d": ["Any process that modulates the frequency, rate or extent of endosome to plasma membrane protein transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905120", "l": "cellular response to haloperidol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060379", "l": "cardiac muscle cell myoblast differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0043367", "l": "CD4-positive, alpha-beta T cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000130", "l": "positive regulation of octopamine signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043968", "l": "histone H2A acetylation", "d": ["The modification of histone H2A by the addition of an acetyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0044537", "l": "regulation of circulating fibrinogen levels", "d": ["Any process that modulates the quantity of fibrinogen circulating in the bloodstream."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0072347", "l": "response to anesthetic", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901522", "l": "positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus", "d": ["Any positive regulation of transcription from RNA polymerase II promoter that is involved in cellular response to chemical stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038018", "l": "Wnt receptor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a Wnt receptor. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019609", "l": "3-hydroxyphenylacetate metabolic process", "d": ["The chemical reactions and pathways involving 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0009988", "l": "cell-cell recognition", "d": ["Cell recognition between cells. May involve the formation of specialized cell junctions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033068", "l": "macrolide biosynthetic process", "d": ["The chemical reactions and pathways leading to the formation of macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097049", "l": "motor neuron apoptotic process", "d": ["Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.41999023820744", "identifiers": [{"i": "GO:0033554", "l": "cellular response to stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090429", "l": "detection of endogenous biotic stimulus", "d": ["The series of events in which an endogenous biotic stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0043327", "l": "chemotaxis to cAMP", "d": ["The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009216", "l": "purine deoxyribonucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097291", "l": "renal phosphate ion absorption", "d": ["A renal system process in which phosphate ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000660", "l": "negative regulation of interleukin-1-mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-1-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902433", "l": "positive regulation of water channel activity involved in maintenance of lens transparency", "d": ["Any positive regulation of water channel activity that is involved in maintenance of lens transparency."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0032400", "l": "melanosome localization", "d": ["Any process in which a melanosome is transported to, and/or maintained in, a specific location within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0036267", "l": "invasive filamentous growth", "d": ["The growth of colonies in filamentous chains of cells into a substrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904996", "l": "positive regulation of leukocyte adhesion to vascular endothelial cell", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071381", "l": "cellular response to prostaglandin F stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0071902", "l": "positive regulation of protein serine/threonine kinase activity", "d": ["Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0048793", "l": "pronephros development", "d": ["The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018387", "l": "N-terminal peptidyl-amino acid deamination to pyruvic acid", "d": ["The oxidative deamination of N-terminal peptidyl-cysteine, or peptidyl-serine, to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0086052", "l": "membrane repolarization during SA node cell action potential", "d": ["The process in which an SA node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000821", "l": "regulation of grooming behavior", "d": ["Any process that modulates the frequency, rate or extent of grooming behavior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905398", "l": "activated CD4-positive, alpha-beta T cell apoptotic process", "d": ["Any apoptotic process in an activated CD4-positive, alpha-beta T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905199", "l": "manchette disassembly", "d": ["The disaggregation of a manchette into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045642", "l": "positive regulation of basophil differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of basophil differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905283", "l": "negative regulation of epidermal growth factor receptor signaling pathway involved in heart process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905748", "l": "hard palate morphogenesis", "d": ["The developmental process by which a hard palate is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901370", "l": "response to glutathione", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.254170199969643", "identifiers": [{"i": "GO:0016052", "l": "carbohydrate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0003404", "l": "optic vesicle morphogenesis", "d": ["The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046929", "l": "negative regulation of neurotransmitter secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0036065", "l": "fucosylation", "d": ["The covalent attachment of a fucosyl group to an acceptor molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031441", "l": "negative regulation of mRNA 3'-end processing", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA 3'-end processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.468544520863134", "identifiers": [{"i": "GO:2000106", "l": "regulation of leukocyte apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of leukocyte apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043547", "l": "positive regulation of GTPase activity", "d": ["Any process that activates or increases the activity of a GTPase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051970", "l": "negative regulation of transmission of nerve impulse", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061903", "l": "positive regulation of 1-phosphatidylinositol-3-kinase activity", "d": ["Any process that starts or increases the frequency or rate of 1-phosphatidylinositol-3-kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0000955", "l": "amino acid catabolic process via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols or carboxylic acids containing one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives, sometimes referred to as fusel acids, may be produced instead of alcohols."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900275", "l": "negative regulation of phospholipase C activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032498", "l": "detection of muramyl dipeptide", "d": ["The series of events in which a muramyl dipeptide stimulus is received by a cell and converted into a molecular signal. Muramyl dipeptide is derived from peptidoglycan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034127", "l": "regulation of MyD88-independent toll-like receptor signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903730", "l": "regulation of phosphatidate phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of phosphatidate phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006265", "l": "DNA topological change", "d": ["The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007072", "l": "positive regulation of transcription involved in exit from mitosis", "d": ["Any process that increases the frequency, rate or extent of transcription as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045059", "l": "positive thymic T cell selection", "d": ["The process of sparing immature T cells in the thymus which react with self-MHC protein complexes with low affinity levels from apoptotic death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0007435", "l": "salivary gland morphogenesis", "d": ["The process in which the anatomical structures of the salivary gland are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.281967957033203", "identifiers": [{"i": "GO:0046434", "l": "organophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-containing organic compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070429", "l": "negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900134", "l": "negative regulation of renin secretion into blood stream", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of renin secretion into blood stream."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033536", "l": "ajugose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042341", "l": "cyanogenic glycoside metabolic process", "d": ["The chemical reactions and pathways involving cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010323", "l": "negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036438", "l": "maintenance of lens transparency", "d": ["A homeostatic process in which the lens is maintained in a highly refractive, transparent state to allow for optimal focusing of light on the retina."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905225", "l": "response to thyrotropin-releasing hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0008298", "l": "intracellular mRNA localization", "d": ["Any process in which mRNA is transported to, or maintained in, a specific location within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006003", "l": "fructose 2,6-bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving fructose 2,6-bisphosphate. The D enantiomer is an important regulator of the glycolytic and gluconeogenic pathways. It inhibits fructose 1,6-bisphosphatase and activates phosphofructokinase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061441", "l": "renal artery morphogenesis", "d": ["The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903016", "l": "negative regulation of exo-alpha-sialidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of exo-alpha-sialidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902295", "l": "synthesis of RNA primer involved in cell cycle DNA replication", "d": ["Any DNA replication, synthesis of RNA primer that is involved in cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018923", "l": "limonene metabolic process", "d": ["The chemical reactions and pathways involving limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0043112", "l": "receptor metabolic process", "d": ["The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0061643", "l": "chemorepulsion of axon", "d": ["The process in which a neuron growth cone is directed to a specific target site in response to a repulsive chemical cue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032811", "l": "negative regulation of epinephrine secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033864", "l": "positive regulation of NAD(P)H oxidase activity", "d": ["Any process that activates or increases the activity of the enzyme NAD(P)H oxidase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140060", "l": "axon arborization", "d": ["The process in which the terminal anatomical structures of an axon are generated and organized into branches of specialised projections, or boutons. An axon is the long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminal branches."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0015705", "l": "iodide transport", "d": ["The directed movement of iodide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900059", "l": "positive regulation of sulfate assimilation", "d": ["Any process that activates or increases the frequency, rate or extent of sulfate assimilation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034372", "l": "very-low-density lipoprotein particle remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0060420", "l": "regulation of heart growth", "d": ["Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0061046", "l": "regulation of branching involved in lung morphogenesis", "d": ["Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904390", "l": "cone retinal bipolar cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a cone retinal bipolar cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060566", "l": "positive regulation of termination of DNA-templated transcription", "d": ["Any process that increases the rate, frequency or extent of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021884", "l": "forebrain neuron development", "d": ["The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033393", "l": "homogalacturonan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of homogalacturonan, a pectidic polymer, characterized by a backbone of 1,4-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:2000104", "l": "negative regulation of DNA-templated DNA replication", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036198", "l": "dTMP salvage", "d": ["Any process which produces dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate) without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0009395", "l": "phospholipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061204", "l": "paramyosin filament assembly or disassembly", "d": ["The formation or disassembly of a filament composed of paramyosin molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0050913", "l": "sensory perception of bitter taste", "d": ["The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904248", "l": "regulation of age-related resistance", "d": ["Any process that modulates the extent of age-related resistance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106034", "l": "protein maturation by [2Fe-2S] cluster transfer", "d": ["The transfer of an assembled [2Fe-2S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0046661", "l": "male sex differentiation", "d": ["The establishment of the sex of a male organism by physical differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0003143", "l": "embryonic heart tube morphogenesis", "d": ["The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904316", "l": "response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019453", "l": "L-cysteine catabolic process via cystine", "d": ["The chemical reactions and pathways resulting in the breakdown of L-cysteine, via the intermediate cystine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0016094", "l": "polyprenol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901958", "l": "negative regulation of cutin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cutin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.598265520774746", "identifiers": [{"i": "GO:0072073", "l": "kidney epithelium development", "d": ["The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0006744", "l": "ubiquinone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903679", "l": "positive regulation of cap-independent translational initiation", "d": ["Any process that activates or increases the frequency, rate or extent of cap-independent translational initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075289", "l": "aplanospore formation", "d": ["The process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141028", "l": "perturbation by symbiont of host microtubule cytoskeleton", "d": ["The process in which an organism effects a change that impairs the structure or function of the host microtubule cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071569", "l": "protein ufmylation", "d": ["Covalent attachment of the ubiquitin-like protein UFM1 to another protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903214", "l": "regulation of protein targeting to mitochondrion", "d": ["Any process that modulates the frequency, rate or extent of protein targeting to mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032084", "l": "regulation of type I site-specific deoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of a type I restriction endodeoxyribonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006919", "l": "activation of cysteine-type endopeptidase activity involved in apoptotic process", "d": ["Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:1905954", "l": "positive regulation of lipid localization", "d": ["Any process that activates or increases the frequency, rate or extent of lipid localization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032355", "l": "response to estradiol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061274", "l": "mesonephric distal tubule development", "d": ["The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045702", "l": "positive regulation of spermatid nuclear differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0050871", "l": "positive regulation of B cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of B cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001061", "l": "D-glycero-D-manno-heptose 7-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a D-glycero-D-manno-heptose 7-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0009739", "l": "response to gibberellin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002149", "l": "hypochlorous acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hypochlorous acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048843", "l": "negative regulation of axon extension involved in axon guidance", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905086", "l": "negative regulation of bioluminescence", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bioluminescence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.980302069293842", "identifiers": [{"i": "GO:0022898", "l": "regulation of transmembrane transporter activity", "d": ["Any process that modulates the frequency, rate or extent of transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901446", "l": "negative regulation of response to propan-1-ol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to propan-1-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0097421", "l": "liver regeneration", "d": ["The regrowth of lost or destroyed liver."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0042147", "l": "retrograde transport, endosome to Golgi", "d": ["The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0043388", "l": "positive regulation of DNA binding", "d": ["Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097473", "l": "retinal rod cell apoptotic process", "d": ["Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033400", "l": "trans-zeatin metabolic process", "d": ["The chemical reactions and pathways involving trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.596630931894587", "identifiers": [{"i": "GO:0030072", "l": "peptide hormone secretion", "d": ["The regulated release of a peptide hormone from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903683", "l": "positive regulation of epithelial cell-cell adhesion involved in epithelium migration", "d": ["Any process that activates or increases the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045648", "l": "positive regulation of erythrocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904518", "l": "protein localization to cytoplasmic microtubule plus-end", "d": ["A process in which a protein is transported to, or maintained in, a location at a cytoplasmic microtubule plus-end."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:1901184", "l": "regulation of ERBB signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of ERBB signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043100", "l": "pyrimidine nucleobase salvage", "d": ["Any process that generates pyrimidine nucleobases, 1,3-diazine organic nitrogenous bases, from derivatives of them without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048890", "l": "lateral line ganglion development", "d": ["The process whose specific outcome is the progression of the lateral line ganglion over time, from its formation to the mature structure. The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006697", "l": "ecdysone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140425", "l": "galactose import across plasma membrane", "d": ["The directed movement of galactose from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033245", "l": "negative regulation of penicillin metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007301", "l": "female germline ring canal formation", "d": ["Assembly of the intercellular bridges that connect the germ-line cells of a female cyst."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048034", "l": "heme O biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007116", "l": "regulation of cell budding", "d": ["Any process that modulates the frequency, rate or extent of the formation and growth of cell buds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000944", "l": "positive regulation of amylopectin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of amylopectin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071609", "l": "chemokine (C-C motif) ligand 5 production", "d": ["The appearance of chemokine (C-C motif) ligand 5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072645", "l": "interferon-delta production", "d": ["The appearance of interferon-delta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0015846", "l": "polyamine transport", "d": ["The directed movement of polyamines, organic compounds containing two or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905949", "l": "negative regulation of calcium ion import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098940", "l": "anterograde trans-synaptic signaling by nitric oxide", "d": ["Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by nitric oxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009644", "l": "response to high light intensity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.892466024748572", "identifiers": [{"i": "GO:0010498", "l": "proteasomal protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010222", "l": "stem vascular tissue pattern formation", "d": ["Vascular tissue pattern formation as it occurs in the stem of vascular plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071106", "l": "adenosine 3',5'-bisphosphate transmembrane transport", "d": ["The process in which adenosine 3',5'-bisphosphate is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071499", "l": "cellular response to laminar fluid shear stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903899", "l": "positive regulation of PERK-mediated unfolded protein response", "d": ["Any process that activates or increases the frequency, rate or extent of the PERK-mediated unfolded protein response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055089", "l": "fatty acid homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000320", "l": "negative regulation of T-helper 17 cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0048366", "l": "leaf development", "d": ["The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0072170", "l": "metanephric tubule development", "d": ["The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042985", "l": "negative regulation of amyloid precursor protein biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1905135", "l": "biotin import across plasma membrane", "d": ["The directed movement of biotin from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019670", "l": "anaerobic glutamate catabolic process", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, yielding energy in the form of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007100", "l": "mitotic centrosome separation", "d": ["Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019596", "l": "mandelate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000913", "l": "preprophase band assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the preprophase band, a dense band of microtubules that marks the position in the cell where cytokinesis will occur in cells that perform cytokinesis by cell plate formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903826", "l": "L-arginine transmembrane transport", "d": ["The directed movement of L-arginine across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033544", "l": "fatty acid beta-oxidation, unsaturated, even number, epimerase pathway", "d": ["A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to cis-2-enoyl-CoA through one more cycle of the core beta-oxidation pathway. Cis-2-enoyl-CoA cannot be completely degraded via the core beta-oxidation pathway because hydratation of cis-2-enoyl-CoA yields D-3-hydroxyacyl-CoA, which is not a substrate for 3-hydroxylacyl-CoA dehydrogenase. Cis-2-enoyl-CoA must enter the so-called epimerase pathway, which involves converting D-3-hydroxyacyl-CoA to L-3-hydroxyacyl-CoA by 3-hydroxylacyl-CoA epimerase or by two stereo-specific enoyl-CoA hydratases. L-3-hydroxyacyl-CoA then returns to the core beta-oxidation pathway. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001315", "l": "UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903137", "l": "regulation of cell wall integrity MAPK cascade", "d": ["Any process that modulates the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.744066580938323", "identifiers": [{"i": "GO:0022604", "l": "regulation of cell morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080143", "l": "regulation of amino acid export", "d": ["Any process that modulates the frequency, rate or extent of amino acid export. Amino acid export is the directed movement of amino acids out of a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902446", "l": "regulation of shade avoidance", "d": ["Any process that modulates the frequency, rate or extent of shade avoidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901117", "l": "cephamycin C catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cephamycin C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904551", "l": "cellular response to arachidonic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0008582", "l": "regulation of synaptic assembly at neuromuscular junction", "d": ["Any process that modulates the frequency, rate or extent of synaptic assembly at neuromuscular junctions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.577676088883429", "identifiers": [{"i": "GO:0072330", "l": "monocarboxylic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045895", "l": "positive regulation of mating-type specific transcription, DNA-templated", "d": ["Any mating-type specific process that activates or increases the rate of cellular DNA-templated transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900603", "l": "tensidol A metabolic process", "d": ["The chemical reactions and pathways involving tensidol A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150072", "l": "positive regulation of arginase activity", "d": ["Any process that activates or increases the frequency, rate or extent of arginase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0052008", "l": "disruption by symbiont of host cellular component", "d": ["The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016488", "l": "farnesol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0060135", "l": "maternal process involved in female pregnancy", "d": ["A reproductive process occurring in the mother that allows an embryo or fetus to develop within it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.675373588411375", "identifiers": [{"i": "GO:0065004", "l": "protein-DNA complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905464", "l": "positive regulation of DNA duplex unwinding", "d": ["Any process that activates or increases the frequency, rate or extent of DNA duplex unwinding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031590", "l": "wybutosine metabolic process", "d": ["The chemical reactions and pathways involving wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0062226", "l": "regulation of adult somatic muscle development", "d": ["Any process that modulates the rate, frequency or extent of adult somatic muscle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0061383", "l": "trabecula morphogenesis", "d": ["The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060223", "l": "retinal rod cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048717", "l": "anterior cibarial plate morphogenesis", "d": ["The process in which the anatomical structures of the anterior cibarial plate are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060716", "l": "labyrinthine layer blood vessel development", "d": ["The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050842", "l": "copper incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide", "d": ["The incorporation of copper into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903215", "l": "negative regulation of protein targeting to mitochondrion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.161881760686384", "identifiers": [{"i": "GO:0042178", "l": "xenobiotic catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090728", "l": "negative regulation of brood size", "d": ["Any process that decreases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090510", "l": "anticlinal cell division", "d": ["A cell division process where the division plane is perpendicular to the surface of the organ. It adds cells to the existing cell layer or cell file."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016039", "l": "absorption of UV light", "d": ["The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035849", "l": "nephric duct elongation", "d": ["The process in which the nephric duct grows along its axis. A nephric duct is a tube that drains a primitive kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "39.001026507922532", "identifiers": [{"i": "GO:0023052", "l": "signaling", "d": ["The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000421", "l": "positive regulation of eosinophil extravasation", "d": ["Any process that activates or increases the frequency, rate or extent of eosinophil extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010987", "l": "negative regulation of high-density lipoprotein particle clearance", "d": ["Any process that decreases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0051351", "l": "positive regulation of ligase activity", "d": ["Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.282738951573606", "identifiers": [{"i": "GO:0140694", "l": "non-membrane-bounded organelle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:0015914", "l": "phospholipid transport", "d": ["The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072696", "l": "positive regulation of DNA recombination at telomere", "d": ["Any process that activates or increases the frequency, rate or extent of DNA recombination within the telomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010982", "l": "regulation of high-density lipoprotein particle clearance", "d": ["Any process that modulates the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904885", "l": "beta-catenin destruction complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a beta-catenin destruction complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0006801", "l": "superoxide metabolic process", "d": ["The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044027", "l": "negative regulation of gene expression via CpG island methylation", "d": ["An epigenetic gene regulation mechanism that negatively regulates gene expression by methylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900835", "l": "negative regulation of emericellin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of emericellin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072226", "l": "metanephric long descending thin limb bend development", "d": ["The process whose specific outcome is the progression of the metanephric long descending thin limb bend over time, from its formation to the mature structure. The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003261", "l": "cardiac muscle progenitor cell migration to the midline involved in heart field formation", "d": ["The orderly movement of a myocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into myocardial cells of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019327", "l": "lead sulfide oxidation", "d": ["The chemical reactions and pathways resulting in the conversion of lead sulfide to lead sulfate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090666", "l": "scaRNA localization to Cajal body", "d": ["A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071237", "l": "cellular response to bacteriocin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035015", "l": "elongation of arista core", "d": ["The increase in length of the aristal core. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905821", "l": "positive regulation of chromosome condensation", "d": ["Any process that activates or increases the frequency, rate or extent of chromosome condensation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010652", "l": "positive regulation of cell communication by chemical coupling", "d": ["Any process that increases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0052315", "l": "phytoalexin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytoalexins, any of a range of substances produced by plants as part of their defense response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0002578", "l": "negative regulation of antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106215", "l": "negative regulation of vesicle fusion with Golgi apparatus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051126", "l": "negative regulation of actin nucleation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140059", "l": "dendrite arborization", "d": ["The process in which the anatomical structures of a dendritic tree are generated and organized into dendritic branches."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075197", "l": "haustorium neck formation", "d": ["The assembly by the symbiont of a neck-like structure for the purpose of penetration into its host organism. The neck-like structure connects haustorium mother cell and haustorium. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044394", "l": "protein malonylation", "d": ["The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900119", "l": "positive regulation of execution phase of apoptosis", "d": ["Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0002548", "l": "monocyte chemotaxis", "d": ["The movement of a monocyte in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0043307", "l": "eosinophil activation", "d": ["The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060818", "l": "inactivation of paternal X chromosome by genomic imprinting", "d": ["Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on the paternal X-chromosome in the XX sex by genomic imprinting."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001744", "l": "insect visual primordium formation", "d": ["Establishment of the optic lobe placode. In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902808", "l": "positive regulation of cell cycle G1/S phase transition", "d": ["Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043013", "l": "negative regulation of fusion of sperm to egg plasma membrane", "d": ["Any process that stops or prevents the binding and fusion of a sperm to the oocyte plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:2000855", "l": "regulation of mineralocorticoid secretion", "d": ["Any process that modulates the frequency, rate or extent of mineralocorticoid secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0071621", "l": "granulocyte chemotaxis", "d": ["The movement of a granulocyte in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903864", "l": "P granule disassembly", "d": ["The disaggregation of a P granule into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0034086", "l": "maintenance of sister chromatid cohesion", "d": ["The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035894", "l": "positive regulation of platelet aggregation in another organism", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of platelet aggregation in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0150119", "l": "negative regulation of protein localization to cell-cell junction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1901553", "l": "malonic acid transmembrane transport", "d": ["The directed movement of malonic acid across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900944", "l": "regulation of isoprene metabolic process", "d": ["Any process that modulates the frequency, rate or extent of isoprene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120084", "l": "endothelial tip cell filopodium assembly", "d": ["The assembly of a filopodium, a thin, stiff protrusion extended by the endothelial tip cell of a vascular sprout."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032201", "l": "telomere maintenance via semi-conservative replication", "d": ["The process in which telomeric DNA is synthesized semi-conservatively by the conventional replication machinery and telomeric accessory factors as part of cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900731", "l": "positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030201", "l": "heparan sulfate proteoglycan metabolic process", "d": ["The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0048339", "l": "paraxial mesoderm development", "d": ["The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072334", "l": "UDP-galactose transmembrane transport", "d": ["The process in which UDP-galactose is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035763", "l": "dorsal motor nucleus of vagus nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the dorsal motor nucleus of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0016118", "l": "carotenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071232", "l": "cellular response to histidine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006597", "l": "spermine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000525", "l": "positive regulation of T cell costimulation", "d": ["Any process that activates or increases the frequency, rate or extent of T cell costimulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042245", "l": "RNA repair", "d": ["Any process that results in the repair of damaged RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042882", "l": "L-arabinose transmembrane transport", "d": ["The process in which L-arabinose, the L-enantiomer of arabinose, is transported across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990387", "l": "isogloboside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a lactosyl-ceramide derivative in which a galactose is linked to the galactose via an alpha 1,3 linkage (vs alpha 1,4 for globosides)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0040024", "l": "dauer larval development", "d": ["The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070885", "l": "negative regulation of calcineurin-NFAT signaling cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT signaling cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001561", "l": "fatty acid alpha-oxidation", "d": ["A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0097374", "l": "sensory neuron axon guidance", "d": ["The process in which the migration of an axon growth cone of a sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A sensory neuron is an afferent neuron conveying sensory impulses."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900521", "l": "regulation of response to amylopectin", "d": ["Any process that modulates the frequency, rate or extent of response to amylopectin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062041", "l": "positive regulation of meiotic sister chromatid arm separation", "d": ["Any process that increases the rate or exent of meiotic sister chromatid arm separation, the cell cycle process in which sister chromatid arms are physically detached from each other during meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007526", "l": "larval somatic muscle development", "d": ["The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097069", "l": "cellular response to thyroxine stimulus", "d": ["A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106024", "l": "negative regulation of pupariation", "d": ["Any process that stops, prevents or reduces the rate of onset of pupariation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "37.110404139640949", "identifiers": [{"i": "GO:0050794", "l": "regulation of cellular process", "d": ["Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0017182", "l": "peptidyl-diphthamide metabolic process", "d": ["The chemical reactions and pathways involving peptidyl-diphthamide, a modified histidine residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071488", "l": "cellular response to very low light intensity stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019487", "l": "anaerobic acetylene catabolic process", "d": ["The chemical reactions and pathways involving acetylene, a colorless, volatile, explosive gas, that occur in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0003254", "l": "regulation of membrane depolarization", "d": ["Any process that modulates the rate, frequency or extent of membrane depolarization. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010442", "l": "guard cell morphogenesis", "d": ["Generation and organization of the polarized cell that is capable of turgor driven movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904254", "l": "regulation of iron ion transmembrane transporter activity", "d": ["Any process that modulates the frequency, rate or extent of an iron transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0042387", "l": "plasmatocyte differentiation", "d": ["The process in which a hemocyte precursor cell acquires the characteristics of the phagocytic blood-cell type, the plasmatocyte. Plasmatocytes are a class of arthropod hemocytes important in the cellular defense response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031270", "l": "pseudopodium retraction", "d": ["The myosin-based contraction and retraction of a pseudopodium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0021692", "l": "cerebellar Purkinje cell layer morphogenesis", "d": ["The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015990", "l": "electron transport coupled proton transport", "d": ["The transport of protons against an electrochemical gradient, using energy from electron transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016254", "l": "preassembly of GPI anchor in ER membrane", "d": ["The stepwise addition of the components of the GPI anchor on to phosphatidylinositol lipids in the endoplasmic reticulum membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071903", "l": "protein N-linked N-acetylglucosaminylation via asparagine", "d": ["A process of protein N-linked glycosylation via asparagine in which N-acetylglucosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)amino-4-oxobutanoic acid residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0016336", "l": "establishment or maintenance of polarity of larval imaginal disc epithelium", "d": ["Any cellular process that results in the specification, formation or maintenance of a polarized larval imaginal disc epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015797", "l": "mannitol transmembrane transport", "d": ["The directed movement of mannitol across a membrane. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060919", "l": "auxin import into cell", "d": ["The directed movement of auxins from outside of a cell into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060827", "l": "regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation", "d": ["Any process that modulates the rate, frequency, or extent of Wnt signaling through beta-catenin that results in the formation of the neural plate anterior/posterior pattern."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140361", "l": "cyclic-GMP-AMP transmembrane import across plasma membrane", "d": ["The directed movement of cyclic-GMP-AMP from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045759", "l": "negative regulation of action potential", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002601", "l": "regulation of antigen processing and presentation of polysaccharide antigen via MHC class II", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060468", "l": "prevention of polyspermy", "d": ["The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018265", "l": "GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-asparagine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a asparaginyl-peptide bond in the carboxy-terminal region of a membrane-associated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000298", "l": "regulation of Rho-dependent protein serine/threonine kinase activity", "d": ["Any process that modulates the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902227", "l": "negative regulation of macrophage colony-stimulating factor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010622", "l": "specification of ovule identity", "d": ["The regionalization process in which the identity of an ovule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905259", "l": "negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:2001252", "l": "positive regulation of chromosome organization", "d": ["Any process that activates or increases the frequency, rate or extent of chromosome organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900154", "l": "regulation of bone trabecula formation", "d": ["Any process that modulates the frequency, rate or extent of bone trabecula formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000301", "l": "negative regulation of synaptic vesicle exocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021610", "l": "facial nerve morphogenesis", "d": ["The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0008344", "l": "adult locomotory behavior", "d": ["Locomotory behavior in a fully developed and mature organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0042660", "l": "positive regulation of cell fate specification", "d": ["Any process that activates or enables a cell to adopt a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036504", "l": "Golgi membrane fusion", "d": ["The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0062208", "l": "positive regulation of pattern recognition receptor signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of a pattern recognition receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090268", "l": "activation of mitotic cell cycle spindle assembly checkpoint", "d": ["Any process that starts the inactive process of a mitotic cell cycle spindle assembly checkpoint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000162", "l": "negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901746", "l": "prephenate(2-) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of prephenate(2-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106120", "l": "positive regulation of sterol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of a sterol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039646", "l": "modulation by virus of host G0/G1 transition checkpoint", "d": ["Any viral process that modulates the frequency, rate or extent of the host cell G0/G1 transition checkpoint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002310", "l": "alpha-beta T cell proliferation involved in immune response", "d": ["The expansion of an alpha-beta T cell population by cell division as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018358", "l": "protein-phytochromobilin linkage via S-phytochromobilin-L-cysteine", "d": ["The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin via S-phytochromobilin-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061189", "l": "positive regulation of sclerotome development", "d": ["Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905397", "l": "activated CD8-positive, alpha-beta T cell apoptotic process", "d": ["Any apoptotic process in an activated CD8-positive, alpha-beta T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900126", "l": "negative regulation of hyaluronan biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060153", "l": "modulation by virus of host cell cycle", "d": ["Any viral process that modulates the rate or extent of progression through the cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902300", "l": "galactarate transmembrane transport", "d": ["The process in which galactaric acid anion (galactarate) is transported across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0050708", "l": "regulation of protein secretion", "d": ["Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097378", "l": "dorsal spinal cord interneuron axon guidance", "d": ["The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A dorsal spinal cord interneuron is an interneuron located in the dorsal part of the spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0051175", "l": "negative regulation of sulfur metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.357413409522593", "identifiers": [{"i": "GO:0010959", "l": "regulation of metal ion transport", "d": ["Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0042873", "l": "aldonate transmembrane transport", "d": ["The process in which aldonate is transported across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034475", "l": "U4 snRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a U4 snRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097214", "l": "positive regulation of lysosomal membrane permeability", "d": ["Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045998", "l": "positive regulation of ecdysteroid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902225", "l": "negative regulation of acrosome reaction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of acrosome reaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002917", "l": "regulation of peripheral B cell anergy", "d": ["Any process that modulates the frequency, rate, or extent of peripheral B cell anergy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045635", "l": "negative regulation of melanocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of melanocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900298", "l": "negative regulation of hexasaccharide transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hexasaccharide transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904958", "l": "positive regulation of midbrain dopaminergic neuron differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of midbrain dopaminergic neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "34.81361856697449", "identifiers": [{"i": "GO:0050896", "l": "response to stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120318", "l": "olfactory sociosexual communication", "d": ["The use of external chemical cues called pheromones to send social and sexual information between members of the same species, leading to specific behavioral responses. Pheromones may be detected by two olfactory sensory circuits, the main olfactory pathway and the vomeronasal system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990029", "l": "vasomotion", "d": ["The rhythmical contraction and relaxation of arterioles, observed as slow and fast waves, with frequencies of 1-2 and 10-20 cpm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904301", "l": "regulation of maternal process involved in parturition", "d": ["Any process that modulates the frequency, rate or extent of maternal process involved in parturition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045348", "l": "positive regulation of MHC class II biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017186", "l": "peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase", "d": ["The chemical reactions and pathways resulting in the formation of peptidyl-pyroglutamic acid, catalyzed by glutaminyl-peptide cyclotransferase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061239", "l": "mesenchymal stem cell differentiation involved in mesonephric nephron morphogenesis", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904268", "l": "positive regulation of Schwann cell chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of Schwann cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901426", "l": "response to furfural", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a furfural stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902518", "l": "response to cyclophosphamide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclophosphamide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010753", "l": "positive regulation of cGMP-mediated signaling", "d": ["Any process that increases the rate, frequency or extent of cGMP-mediated signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000185", "l": "regulation of phosphate transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of phosphate transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061160", "l": "regulation of establishment of bipolar cell polarity regulating cell shape", "d": ["Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0042545", "l": "cell wall modification", "d": ["The series of events leading to chemical and structural alterations of an existing cell wall that can result in loosening, increased extensibility or disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903487", "l": "regulation of lactation", "d": ["Any process that modulates the frequency, rate or extent of lactation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0101010", "l": "pulmonary blood vessel remodeling", "d": ["The reorganization or renovation of existing pulmonary blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0050858", "l": "negative regulation of antigen receptor-mediated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901748", "l": "leukotriene D4 metabolic process", "d": ["The chemical reactions and pathways involving leukotriene D4."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032249", "l": "regulation of adenosine transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007428", "l": "primary branching, open tracheal system", "d": ["Formation of primary branches in the open tracheal system. These form from small groups of cells that migrate out at specific positions, organizing into tubes as they migrate. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045091", "l": "regulation of single stranded viral RNA replication via double stranded DNA intermediate", "d": ["Any process that modulates the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0150172", "l": "regulation of phosphatidylcholine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylcholine metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015699", "l": "antimonite transport", "d": ["The directed movement of antimonite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070936", "l": "protein K48-linked ubiquitination", "d": ["A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0017009", "l": "protein-phycocyanobilin linkage", "d": ["The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015944", "l": "formate oxidation", "d": ["The chemical reactions and pathways by which formate is converted to CO2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003249", "l": "cell proliferation involved in heart valve morphogenesis", "d": ["The multiplication or reproduction of cells that contributes to the shaping of a heart valve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061417", "l": "negative regulation of transcription from RNA polymerase II promoter in response to oxidative stress", "d": ["Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.264441957026364", "identifiers": [{"i": "GO:1901698", "l": "response to nitrogen compound", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071302", "l": "cellular response to vitamin B2", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034465", "l": "response to carbon monoxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033394", "l": "beta-alanine biosynthetic process via 1,3 diaminopropane", "d": ["The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 1,3 diaminopropane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0001666", "l": "response to hypoxia", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019518", "l": "L-threonine catabolic process to glycine", "d": ["The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form to form 2-amino-3-oxobutanoate, which is subsequently converted to glycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0042637", "l": "catagen", "d": ["The regression phase of the hair cycle during which cell proliferation ceases, the hair follicle shortens, and an anchored club hair is produced."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0090088", "l": "regulation of oligopeptide transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044480", "l": "envenomation resulting in positive regulation of mast cell degranulation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of blood mast cell degranulation in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905044", "l": "regulation of Schwann cell proliferation involved in axon regeneration", "d": ["Any process that modulates the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.647680762863281", "identifiers": [{"i": "GO:0032774", "l": "RNA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018115", "l": "peptidyl-S-diphytanylglycerol diether-L-cysteine biosynthetic process from peptidyl-cysteine", "d": ["The modification of cysteine to form peptidyl-S-diphytanylglycerol diether-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050814", "l": "epothilone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0110118", "l": "negative regulation of compound eye photoreceptor cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036371", "l": "protein localization to T-tubule", "d": ["A process in which a protein is transported to, or maintained in, the T-tubule. The T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044513", "l": "envenomation resulting in modulation of G protein-coupled receptor activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of G protein-coupled receptor activity in of the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.240853996207278", "identifiers": [{"i": "GO:0045833", "l": "negative regulation of lipid metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046431", "l": "(R)-4-hydroxymandelate metabolic process", "d": ["The chemical reactions and pathways involving (R)-4-hydroxymandelate, the anion of a hydroxylated derivative of mandelate (alpha-hydroxybenzeneacetate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048597", "l": "post-embryonic camera-type eye morphogenesis", "d": ["The process in which the anatomical structures of the eye are generated and organized during post-embryonic development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0090677", "l": "reversible differentiation", "d": ["A phenotypic switching process where a cell reversibly differentiates and dedifferentiates from one cell type into another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034392", "l": "negative regulation of smooth muscle cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071273", "l": "morphine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034129", "l": "positive regulation of MyD88-independent toll-like receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010450", "l": "inflorescence meristem growth", "d": ["The increase in size or mass of an inflorescence meristem, a population of undifferentiated cells in a plant shoot which produces small leaves and then floral meristems, which will give rise to flowers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0002090", "l": "regulation of receptor internalization", "d": ["Any process that modulates the frequency, rate or extent of receptor internalization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019406", "l": "hexitol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hexitols, any alditol with a chain of six carbon atoms in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0006458", "l": "'de novo' protein folding", "d": ["The process of assisting in the folding of a nascent peptide chain into its correct tertiary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075070", "l": "adhesion of symbiont hyphopodium to host", "d": ["The attachment of a hyphopodium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0008535", "l": "respiratory chain complex IV assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055107", "l": "Golgi to secretory granule transport", "d": ["The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0043944", "l": "negative regulation of asexual sporulation resulting in formation of a cellular spore", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.892466024748572", "identifiers": [{"i": "GO:1901653", "l": "cellular response to peptide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035709", "l": "memory T cell activation", "d": ["The change in morphology and behavior of a memory T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019688", "l": "purine deoxyribonucleoside interconversion", "d": ["The chemical reactions and pathways by which a purine deoxyribonucleoside is synthesized from another purine deoxyribonucleoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.415767841334464", "identifiers": [{"i": "GO:0001817", "l": "regulation of cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of production of a cytokine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0061642", "l": "chemoattraction of axon", "d": ["The process in which a neuron growth cone is directed to a specific target site in response to an attractive chemical signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904997", "l": "regulation of leukocyte adhesion to arterial endothelial cell", "d": ["Any process that modulates the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0093001", "l": "glycolysis from storage polysaccharide through glucose-1-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of a storage polysaccharide into pyruvate through a glucose-1-phosphate intermediate, with the concomitant production of a small amount of ATP and the reduction of NAD to NADH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021689", "l": "cerebellar molecular layer structural organization", "d": ["The process that contributes to the act of creating the structural organization of the cerebellar molecular layer. This process pertains to the physical shaping of a rudimentary structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010265", "l": "SCF complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the SKP1-Cullin/Cdc53-F-box protein ubiquitin ligase (SCF) complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044752", "l": "response to human chorionic gonadotropin", "d": ["Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904473", "l": "response to L-dopa", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006315", "l": "homing of group II introns", "d": ["Lateral transfer of a group II intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group II introns are self-splicing introns with a conserved secondary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009264", "l": "deoxyribonucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042854", "l": "eugenol metabolic process", "d": ["The chemical reactions and pathways involving eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901109", "l": "granaticin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of granaticin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000162", "l": "tryptophan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902754", "l": "positive regulation of renal amino acid absorption", "d": ["Any process that activates or increases the frequency, rate or extent of renal amino acid absorption."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0048255", "l": "mRNA stabilization", "d": ["Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042215", "l": "anaerobic phenol-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.451980028874367", "identifiers": [{"i": "GO:0006915", "l": "apoptotic process", "d": ["A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043602", "l": "nitrate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nitrates, inorganic or organic salts and esters of nitric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009955", "l": "adaxial/abaxial pattern specification", "d": ["The regionalization process in which differences in cell differentiation along the adaxial/abaxial are generated. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046776", "l": "suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I", "d": ["Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class I transmembrane protein complex. One mechanism of suppression is by direct inhibition of host tapasin, a type I transmembrane protein essential for the optimal expression of stable MHC class I molecules on the host cell surface. By inhibiting host tapasin activity, viruses can prevent presentation of their antigens at the cell surface, and thereby evade the host anti-viral immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0080112", "l": "seed growth", "d": ["The increase in size or mass of a seed. A seed is a propagating organ formed in the reproductive cycle of a spermatophyte, derived from the ovule and enclosing an embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002638", "l": "negative regulation of immunoglobulin production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034384", "l": "high-density lipoprotein particle clearance", "d": ["The process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097751", "l": "spore-bearing structure formation", "d": ["The process of generating a spore-bearing structure. A spore-bearing structure is an anatomical structure that produces new spores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.582174935760108", "identifiers": [{"i": "GO:0034968", "l": "histone lysine methylation", "d": ["The modification of a histone by addition of one or more methyl groups to a lysine residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0010155", "l": "regulation of proton transport", "d": ["Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1900190", "l": "regulation of single-species biofilm formation", "d": ["Any process that modulates the frequency, rate or extent of single-species biofilm formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905942", "l": "regulation of formation of growth cone in injured axon", "d": ["Any process that modulates the frequency, rate or extent of formation of growth cone in injured axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905780", "l": "regulation of phosphatidylserine exposure on apoptotic cell surface", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905662", "l": "negative regulation of telomerase RNA reverse transcriptase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA reverse transcriptase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900181", "l": "negative regulation of protein localization to nucleus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.586422797268227", "identifiers": [{"i": "GO:0006403", "l": "RNA localization", "d": ["A process in which RNA is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0034067", "l": "protein localization to Golgi apparatus", "d": ["A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.747746368481451", "identifiers": [{"i": "GO:0035725", "l": "sodium ion transmembrane transport", "d": ["A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0031554", "l": "regulation of termination of DNA-templated transcription", "d": ["Any process that modulates the frequency, rate, extent, or location of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0050764", "l": "regulation of phagocytosis", "d": ["Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0006063", "l": "uronic acid metabolic process", "d": ["The chemical reactions and pathways involving uronic acid, any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.764920414113355", "identifiers": [{"i": "GO:0006720", "l": "isoprenoid metabolic process", "d": ["The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905404", "l": "positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015967", "l": "diadenosine tetraphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903837", "l": "regulation of mRNA 3'-UTR binding", "d": ["Any process that modulates the frequency, rate or extent of mRNA 3'-UTR binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900361", "l": "negative regulation of pentasaccharide transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pentasaccharide transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.550707717106313", "identifiers": [{"i": "GO:0031667", "l": "response to nutrient levels", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061132", "l": "pancreas induction", "d": ["The close range interaction of two or more cells or tissues that causes the cells of the gut to change their fates and specify the development of the pancreas."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0006553", "l": "lysine metabolic process", "d": ["The chemical reactions and pathways involving lysine, 2,6-diaminohexanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.760111289607934", "identifiers": [{"i": "GO:0051053", "l": "negative regulation of DNA metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0032784", "l": "regulation of DNA-templated transcription elongation", "d": ["Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.9148261867131", "identifiers": [{"i": "GO:0061007", "l": "hepaticobiliary system process", "d": ["An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0044062", "l": "regulation of excretion", "d": ["Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:1903018", "l": "regulation of glycoprotein metabolic process", "d": ["Any process that modulates the frequency, rate or extent of glycoprotein metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009186", "l": "deoxyribonucleoside diphosphate metabolic process", "d": ["The chemical reactions and pathways involving a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010828", "l": "positive regulation of glucose transmembrane transport", "d": ["Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051114", "l": "peptidyl-histidine uridylylation", "d": ["The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine) or peptidyl-3'-(phospho-5'-uridine)-L-histidine (otherwise known as pi-UMP-histidine, pros-UMP-histidine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051881", "l": "regulation of mitochondrial membrane potential", "d": ["Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046101", "l": "hypoxanthine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042179", "l": "nicotine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008070", "l": "maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded", "d": ["Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by cells of the germ line."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035119", "l": "embryonic pelvic fin morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075046", "l": "positive regulation of formation by symbiont of haustorium for nutrient acquisition from host", "d": ["Any process that activates or increases the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097577", "l": "sequestering of iron ion", "d": ["The process of binding or confining iron ions such that they are separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099560", "l": "synaptic membrane adhesion", "d": ["The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034172", "l": "negative regulation of toll-like receptor 11 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 11 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018242", "l": "protein O-linked glycosylation via serine", "d": ["The glycosylation of protein via the O3 atom of peptidyl-serine, forming O3-glycosyl-L-serine; the most common forms are N-acetylgalactosaminyl, mannosyl, galactosyl, and xylosyl serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000080", "l": "negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901899", "l": "positive regulation of relaxation of cardiac muscle", "d": ["Any process that activates or increases the frequency, rate or extent of relaxation of cardiac muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0033334", "l": "fin morphogenesis", "d": ["The process in which the anatomical structures of a fin are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032534", "l": "regulation of microvillus assembly", "d": ["A process that modulates the formation of a microvillus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0036301", "l": "macrophage colony-stimulating factor production", "d": ["The appearance of macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904475", "l": "regulation of small GTPase binding", "d": ["Any process that modulates the frequency, rate or extent of small GTPase binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900818", "l": "ochratoxin A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ochratoxin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.282738951573606", "identifiers": [{"i": "GO:0006941", "l": "striated muscle contraction", "d": ["A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060263", "l": "regulation of respiratory burst", "d": ["Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021807", "l": "motogenic signaling initiating cell movement in cerebral cortex", "d": ["The interaction of soluble factors and receptors that result in the movement of cells in the primitive cerebral cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006384", "l": "transcription initiation at RNA polymerase III promoter", "d": ["A transcription initiation process that takes place at a RNA polymerase III gene promoter. Transfer RNAs (tRNA) genes, as well as some other non-coding RNAs, are transcribed by RNA polymerase III."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.797471414058734", "identifiers": [{"i": "GO:0043413", "l": "macromolecule glycosylation", "d": ["The covalent attachment of a glycosyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002024", "l": "diet induced thermogenesis", "d": ["The process that results in increased metabolic rate in tissues of an organism. It is triggered by the detection of dietary excess. This process is achieved via signalling in the sympathetic nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.232064878529073", "identifiers": [{"i": "GO:1903169", "l": "regulation of calcium ion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0021605", "l": "cranial nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0071696", "l": "ectodermal placode development", "d": ["The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000148", "l": "regulation of planar cell polarity pathway involved in ventricular septum morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035629", "l": "N-terminal protein amino acid N-linked glycosylation", "d": ["Addition of a carbohydrate or carbohydrate derivative unit via a nitrogen (N) atom of the N-terminal amino acid of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009601", "l": "detection of insect", "d": ["The series of events in which a stimulus from an insect is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018883", "l": "caprolactam metabolic process", "d": ["The chemical reactions and pathways involving caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid used in manufacture of synthetic fibers of the polyamide type. It can cause local irritation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903997", "l": "positive regulation of non-membrane spanning protein tyrosine kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106247", "l": "negative regulation of poly(A)-specific ribonuclease activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of poly(A)-specific ribonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.453669357020111", "identifiers": [{"i": "GO:0019219", "l": "regulation of nucleobase-containing compound metabolic process", "d": ["Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018061", "l": "peptidyl-L-3-phenyllactic acid biosynthetic process from peptidyl-phenylalanine", "d": ["The modification of a N-terminal peptidyl-phenylalanine residue by either oxidative deamination or by transamination and subsequent reduction to form peptidyl-L-3-phenyllactic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0051582", "l": "positive regulation of neurotransmitter uptake", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036223", "l": "cellular response to adenine starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of adenine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0006354", "l": "DNA-templated transcription elongation", "d": ["The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "48.180622106800328", "identifiers": [{"i": "GO:0048523", "l": "negative regulation of cellular process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002868", "l": "negative regulation of B cell deletion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell deletion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010065", "l": "primary meristem tissue development", "d": ["The process whose specific outcome is the progression of the primary meristem over time, from formation to the mature structure, as it occurs during plant embryogenesis. The primary meristem tissue is the protoderm, ground meristem and procambium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075017", "l": "regulation of appressorium formation", "d": ["Any process that modulates the frequency, rate or extent of symbiont appressorium formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904666", "l": "regulation of ubiquitin protein ligase activity", "d": ["Any process that modulates the frequency, rate or extent of ubiquitin protein ligase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009835", "l": "fruit ripening", "d": ["An developmental maturation process that has as participant a fruit. Ripening causes changes in one or more characteristics of a fruit (color, aroma, flavor, texture, hardness, cell wall structure) and may make it more attractive to animals and aid in seed dispersal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018156", "l": "peptide cross-linking via (2S,3S,6R)-3-methyl-lanthionine", "d": ["The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,6R)-3-methyl-lanthionine (3-methyl-L-lanthionine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0051230", "l": "spindle disassembly", "d": ["The controlled breakdown of the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0034406", "l": "cell wall beta-glucan metabolic process", "d": ["The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035561", "l": "regulation of chromatin binding", "d": ["Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901792", "l": "3-(2,3-dihydroxyphenyl)propanoate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 3-(2,3-dihydroxyphenyl)propanoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044873", "l": "lipoprotein localization to membrane", "d": ["A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072674", "l": "multinuclear osteoclast differentiation", "d": ["The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901332", "l": "negative regulation of lateral root development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lateral root development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903919", "l": "negative regulation of actin filament severing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of actin filament severing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.366262559334615", "identifiers": [{"i": "GO:0018022", "l": "peptidyl-lysine methylation", "d": ["The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045779", "l": "negative regulation of bone resorption", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160059", "l": "programmed cell death in response to retinoic acid", "d": ["Cell death resulting from activation of endogenous cellular processes and occurring as a result of a retinoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060928", "l": "atrioventricular node cell development", "d": ["The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061590", "l": "calcium activated phosphatidylcholine scrambling", "d": ["The movement of a population of phosphatidylcholine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905406", "l": "positive regulation of mitotic cohesin loading", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cohesin loading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.881467751602372", "identifiers": [{"i": "GO:0030431", "l": "sleep", "d": ["Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043578", "l": "nuclear matrix organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070169", "l": "positive regulation of biomineral tissue development", "d": ["Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010597", "l": "green leaf volatile biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of volatile molecules emitted from green plants, such as hexenal, hexenol and hexenyl acetate, from linoleic acid or linolenic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001827", "l": "inner cell mass cell fate commitment", "d": ["The cell fate commitment of precursor cells that will become inner cell mass cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000461", "l": "endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage at the 3'-end of the SSU-rRNA from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0036491", "l": "regulation of translation initiation in response to endoplasmic reticulum stress", "d": ["Any process that modulates the frequency, rate or extent of translation initiation, as a result of endoplasmic reticulum stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051152", "l": "positive regulation of smooth muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0022904", "l": "respiratory electron transport chain", "d": ["A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010148", "l": "transpiration", "d": ["Release of water by the plant into the air as water vapor mainly through leaves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903842", "l": "response to arsenite ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905590", "l": "fibronectin fibril organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a fibronectin fibril."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000957", "l": "regulation of cyclodextrin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cyclodextrin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0060147", "l": "regulation of post-transcriptional gene silencing", "d": ["Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048314", "l": "embryo sac morphogenesis", "d": ["The process in which the anatomical structures of the embryo sac are generated and organized. The embryo sac develops from the megaspore in heterosporous plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009718", "l": "anthocyanin-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060658", "l": "nipple morphogenesis", "d": ["The process in which the nipple is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019243", "l": "methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione", "d": ["The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007295", "l": "growth of a germarium-derived egg chamber", "d": ["Growth of the egg chamber between the time it leaves the germarium and the onset of vitellogenesis. During this time both nurse cells and the oocyte undergo developmental changes including nuclear organization and cytoplasmic growth. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904550", "l": "response to arachidonic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031042", "l": "O-glycan processing, core 6", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 6 O-glycan structure, GlcNAc-beta-(1->6)-GalNAc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1902547", "l": "regulation of cellular response to vascular endothelial growth factor stimulus", "d": ["Any process that modulates the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090372", "l": "positive regulation of glycerol transport", "d": ["Any process that increases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071785", "l": "endoplasmic reticulum cisternal network maintenance", "d": ["The organization process that preserves the endoplasmic reticulum (ER) cisternal network in a stable functional or structural state. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0099117", "l": "protein transport along microtubule to cell tip", "d": ["The movement of a protein along a microtubule to the cell-tip, mediated by motor proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1901857", "l": "positive regulation of cellular respiration", "d": ["Any process that activates or increases the frequency, rate or extent of cellular respiration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098817", "l": "evoked excitatory postsynaptic potential", "d": ["A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell induced by the evoked release of many vesicles of excitatory neurotransmitter at the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0072417", "l": "response to spindle checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of spindle checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060604", "l": "mammary gland duct cavitation", "d": ["Creation of the central hole of the mammary gland duct by the hollowing out of a solid rod."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090421", "l": "embryonic meristem initiation", "d": ["Initiation of a region of tissue in a plant embryo that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.576969997299727", "identifiers": [{"i": "GO:0008284", "l": "positive regulation of cell population proliferation", "d": ["Any process that activates or increases the rate or extent of cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019093", "l": "mitochondrial RNA localization", "d": ["Any process in which mitochondrial RNA is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009271", "l": "phage shock", "d": ["A response by bacterial cells to a variety of stresses including filamentous phage infection, mislocalization of envelope proteins, extremes of temperature, osmolarity or ethanol concentration, and the presence of proton ionophores such as carbonylcyanide m-chlorophenylhydrazone (CCCP), that involves expression of the phage shock protein operon, and acts to protect the bacterial cells from damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070791", "l": "cleistothecium development", "d": ["The process whose specific outcome is the progression of the cleistothecium over time, from its formation to the mature structure. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062056", "l": "compound eye pigment cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a compound eye pigment cell, a cell of the retina containing screening pigments that functions to screen photoreceptors from light leaking from adjacent ommatidia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0043243", "l": "positive regulation of protein-containing complex disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046073", "l": "dTMP metabolic process", "d": ["The chemical reactions and pathways involving dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000464", "l": "positive regulation of astrocyte chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of astrocyte chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019440", "l": "tryptophan catabolic process to indole-3-acetate", "d": ["The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including indole-3-acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0043620", "l": "regulation of DNA-templated transcription in response to stress", "d": ["Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009253", "l": "peptidoglycan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902125", "l": "(+)-pinoresinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (+)-pinoresinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071613", "l": "granzyme B production", "d": ["The appearance of granzyme B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036210", "l": "protein modification process in another organism", "d": ["The covalent alteration performed by one organism of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) in another organism. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035811", "l": "negative regulation of urine volume", "d": ["Any process that decreases the amount of urine excreted from the body over a unit of time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0006972", "l": "hyperosmotic response", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0032612", "l": "interleukin-1 production", "d": ["The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046276", "l": "methylgallate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.672305786814945", "identifiers": [{"i": "GO:0072080", "l": "nephron tubule development", "d": ["The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0031086", "l": "nuclear-transcribed mRNA catabolic process, deadenylation-independent decay", "d": ["A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.444551060876734", "identifiers": [{"i": "GO:0045453", "l": "bone resorption", "d": ["The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032750", "l": "positive regulation of interleukin-26 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-26 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0014041", "l": "regulation of neuron maturation", "d": ["Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900726", "l": "osmoregulated periplasmic glucan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of osmoregulated periplasmic glucan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0048070", "l": "regulation of developmental pigmentation", "d": ["Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905937", "l": "negative regulation of germ cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043481", "l": "anthocyanin accumulation in tissues in response to UV light", "d": ["The aggregation of the pigment anthocyanin in a particular location in a tissue, occurring in response to a UV light stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062174", "l": "brexanolone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of brexanolone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.980302069293842", "identifiers": [{"i": "GO:0042254", "l": "ribosome biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052651", "l": "monoacylglycerol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044694", "l": "pore-mediated entry of viral genome into host cell", "d": ["Injection by a non-enveloped virus of the viral genome into the host cytoplasm through creation of a pore or channel in the host cell membrane(s). Usually mediated by a viral pore-forming peptide associated with the viral capsid or bacteriophage tail."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071612", "l": "IP-10 production", "d": ["The appearance of IP-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140879", "l": "conidiogenone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of conidiogenone , a diterpene known to induce the conidiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009396", "l": "folic acid-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of folic acid and its derivatives."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072005", "l": "maintenance of kidney identity", "d": ["The process in which the identity of a kidney is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045950", "l": "negative regulation of mitotic recombination", "d": ["Any process that inhibits or decreases the rate of DNA recombination during mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043181", "l": "vacuolar sequestering", "d": ["The process of transporting a substance into, and confining within, a vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990643", "l": "cellular response to granulocyte colony-stimulating factor", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072390", "l": "phenol metabolic process", "d": ["The chemical reactions and pathways involving phenol, a compound that consists of a benzene ring with one attached hydroxyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035733", "l": "hepatic stellate cell activation", "d": ["A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0061548", "l": "ganglion development", "d": ["The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001209", "l": "positive regulation of transcription elongation by RNA polymerase I", "d": ["Any process that activates or increases the frequency, rate or extent of transcription elongation from RNA polymerase I promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0007500", "l": "mesodermal cell fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0061984", "l": "catabolite repression", "d": ["A process in which the presence of one nutrient source leads to a decrease in the frequency, rate, or extent of processes involved in the metabolism of other nutrient sources."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003247", "l": "post-embryonic cardiac muscle cell growth involved in heart morphogenesis", "d": ["The growth of a cardiac muscle cell during the postembryonic period that contributes to the shaping of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901444", "l": "positive regulation of response to furfural", "d": ["Any process that activates or increases the frequency, rate or extent of response to furfural."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990426", "l": "mitotic recombination-dependent replication fork processing", "d": ["Replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070708", "l": "RNA cytidine insertion", "d": ["The modification of an RNA molecule by insertion of a cytidine nucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903702", "l": "esophagus development", "d": ["The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033693", "l": "neurofilament bundle assembly", "d": ["The assembly of neurofilaments into bundles, in which the filaments are longitudinally oriented, with numerous crossbridges between them. Neurofilament bundles may be cross-linked to each other, to membrane-bounded organelles or other cytoskeletal structures such as microtubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060894", "l": "limb spinous cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a limb spinous cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0086045", "l": "membrane depolarization during AV node cell action potential", "d": ["The process in which AV node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070397", "l": "wall teichoic acid metabolic process", "d": ["The chemical reactions and pathways involving wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903088", "l": "5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport", "d": ["The process in which 5-amino-1-ribofuranosylimidazole-4-carboxamide is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006316", "l": "movement of group I intron", "d": ["Lateral transfer of a group I intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group I introns are self-splicing introns that use guanosine as a cofactor in the splicing reaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0046176", "l": "aldonic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032837", "l": "distributive segregation", "d": ["The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during a normally chiasmate meiosis under the condition that chiasma have not occurred between a particular pair of homologs. Distributive segregation is a backup mechanism to ensure the segregation of homologs that have failed to cross over - either as a consequence of mutation or not, as, for example, the 4th chromosome of Drosophila melanogaster (which never exchanges, presumably due to its small size) - but nevertheless segregate normally."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.282738951573606", "identifiers": [{"i": "GO:1901264", "l": "carbohydrate derivative transport", "d": ["The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000308", "l": "negative regulation of tumor necrosis factor (ligand) superfamily member 11 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071169", "l": "establishment of protein localization to chromatin", "d": ["The directed movement of a protein to a part of a chromosome that is organized into chromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140708", "l": "CAT tailing", "d": ["The C-terminal elongation of 60S-anchored stalled nascent polypeptide chains with untemplated alanine and threonine tails (CAT tails). CAT tails participate in the recognition of stalled nascent chains by the ribosome quality control sytem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106217", "l": "tRNA C3-cytosine methylation", "d": ["The process whereby a cytosine in a tRNA is methylated at position 3 of the cytosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:1900428", "l": "regulation of filamentous growth of a population of unicellular organisms", "d": ["Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042117", "l": "monocyte activation", "d": ["The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048700", "l": "acquisition of desiccation tolerance in seed", "d": ["The process in which a seed acquires tolerance to severe drying, before entering into a dry, either dormant or quiescent state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140604", "l": "mycofactocin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the coenzyme mycofactocin, a variably glycosylated small molecule electron pair carrier derived from the C-terminal valine-tyrosine dipeptide of the ribosomally translated precursor peptide MftA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990192", "l": "collecting lymphatic vessel constriction", "d": ["A decrease in the diameter of collecting lymphatic vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042746", "l": "circadian sleep/wake cycle, wakefulness", "d": ["The part of the circadian sleep/wake cycle where the organism is not asleep."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.598265520774746", "identifiers": [{"i": "GO:0006664", "l": "glycolipid metabolic process", "d": ["The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0043266", "l": "regulation of potassium ion transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900012", "l": "positive regulation of corticotropin-releasing hormone receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of corticotropin-releasing hormone receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030838", "l": "positive regulation of actin filament polymerization", "d": ["Any process that activates or increases the frequency, rate or extent of actin polymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016031", "l": "tRNA import into mitochondrion", "d": ["The process in which a tRNA is transported from the cytosol into the mitochondrial matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051918", "l": "negative regulation of fibrinolysis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901819", "l": "alpha-zeacarotene metabolic process", "d": ["The chemical reactions and pathways involving alpha-zeacarotene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036170", "l": "filamentous growth of a population of unicellular organisms in response to starvation", "d": ["The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050969", "l": "detection of chemical stimulus involved in magnetoreception", "d": ["The series of events involved in magnetoception in which a chemical stimulus is received and converted into a molecular signal. It is believed that organisms such as birds and salamanders interpret product ratios in chemical reactions which involve transitions between different spin states."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006621", "l": "protein retention in ER lumen", "d": ["The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070929", "l": "trans-translation", "d": ["A translational elongation process in which transfer of a translating ribosome from one mRNA to another RNA template takes place. Trans-translation occurs during tmRNA release of stalled ribosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032499", "l": "detection of peptidoglycan", "d": ["The series of events in which a peptidoglycan stimulus is received by a cell and converted into a molecular signal. Peptidoglycan is a bacterial cell wall macromolecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036291", "l": "protein cis-autophosphorylation", "d": ["The phosphorylation by a protein of one or more of its own amino acid residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021914", "l": "negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling that is involved in the patterns of cell differentiation in the ventral spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:1990266", "l": "neutrophil migration", "d": ["The movement of a neutrophil within or between different tissues and organs of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046196", "l": "4-nitrophenol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046088", "l": "cytidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cytidine, cytosine riboside, a widely distributed nucleoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900991", "l": "scopolamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of scopolamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097496", "l": "blood vessel lumen ensheathment", "d": ["A blood vessel lumenization process that occurs by blood vessel endothelial cells delaminating and aligning along the inner surface of an existing luminal space, extending the open ended lumen, and joining to other blood vessels to form a complete blood vessel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035297", "l": "regulation of Malpighian tubule diameter", "d": ["Ensuring that the Malpighian tubule is the correct width. Malpighian tubules have a uniform circumference along their length; the circumference of the tubes is eight cells during the time the cells are dividing, after which the cells rearrange producting tubes with a cirumference of two cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048727", "l": "posterior cibarial plate development", "d": ["The process whose specific outcome is the progression of the posterior cibarial plate over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0045923", "l": "positive regulation of fatty acid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901778", "l": "pentalenolactone metabolic process", "d": ["The chemical reactions and pathways involving pentalenolactone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010086", "l": "embryonic root morphogenesis", "d": ["The process in which the anatomical structures of the embryonic root are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061795", "l": "Golgi lumen acidification", "d": ["Any process that reduces the pH of the Golgi lumen, measured by the concentration of the hydrogen ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902012", "l": "poly(ribitol phosphate) teichoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(ribitol phosphate) teichoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0140212", "l": "regulation of long-chain fatty acid import into cell", "d": ["Any process that modulates the frequency, rate or extent of long-chain fatty acid import into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0032479", "l": "regulation of type I interferon production", "d": ["Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900820", "l": "orlandin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of orlandin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044497", "l": "positive regulation of blood pressure in another organism", "d": ["A process by which one organism increases the force with which blood travels through the circulatory system of another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000202", "l": "positive regulation of ribosomal subunit export from nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of ribosomal subunit export from nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009861", "l": "jasmonic acid and ethylene-dependent systemic resistance", "d": ["The jasmonic acid and ethylene (ethene) dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903229", "l": "xanthosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of xanthosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.967140482697559", "identifiers": [{"i": "GO:2001251", "l": "negative regulation of chromosome organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007339", "l": "binding of sperm to zona pellucida", "d": ["The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905844", "l": "negative regulation of cellular response to gamma radiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to gamma radiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045115", "l": "regulation of beta 2 integrin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003034", "l": "detection of increased carbon dioxide by aortic body chemoreceptor signaling", "d": ["The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in an aortic body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044632", "l": "negative regulation of complement activation, lectin pathway in another organism", "d": ["Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway, in a different organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903323", "l": "regulation of snoRNA metabolic process", "d": ["Any process that modulates the frequency, rate or extent of snoRNA metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021584", "l": "pons formation", "d": ["The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0032273", "l": "positive regulation of protein polymerization", "d": ["Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0008045", "l": "motor neuron axon guidance", "d": ["The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0017003", "l": "protein-heme linkage", "d": ["The covalent linkage of heme and a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035765", "l": "motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation", "d": ["The orderly movement of a motor neuron precursor cell that contributes to formation of the dorsal motor nucleus of the vagus nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090280", "l": "positive regulation of calcium ion import", "d": ["Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018983", "l": "Z-phenylacetaldoxime metabolic process", "d": ["The chemical reactions and pathways involving Z-phenylacetaldoxime, a member of the glucosinolate group of compounds, a class of natural products that are gaining increasing interest as cancer-preventing agents and crop protectants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0014718", "l": "positive regulation of satellite cell activation involved in skeletal muscle regeneration", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010730", "l": "negative regulation of hydrogen peroxide biosynthetic process", "d": ["Any process that decreases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032664", "l": "regulation of interleukin-20 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-20 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.187403162058388", "identifiers": [{"i": "GO:0051651", "l": "maintenance of location in cell", "d": ["Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061772", "l": "xenobiotic transport across blood-nerve barrier", "d": ["The directed movement of a xenobiotic through the blood-nerve barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046780", "l": "suppression by virus of host mRNA splicing", "d": ["Any viral process that inhibits the splicing of host mRNA, thus reducing host protein production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061369", "l": "negative regulation of testicular blood vessel morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000376", "l": "positive regulation of oxygen metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of oxygen metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904236", "l": "negative regulation of substrate-dependent cell migration, cell attachment to substrate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033590", "l": "response to cobalamin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901459", "l": "positive regulation of response to acetate", "d": ["Any process that activates or increases the frequency, rate or extent of response to acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903787", "l": "negative regulation of glutathione biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glutathione biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0010506", "l": "regulation of autophagy", "d": ["Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061283", "l": "specification of mesonephric distal tubule identity", "d": ["The process in which the distal tubule of the mesonephric nephron acquires its identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.226136141113301", "identifiers": [{"i": "GO:0042391", "l": "regulation of membrane potential", "d": ["Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0009240", "l": "isopentenyl diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002666", "l": "positive regulation of T cell tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904337", "l": "positive regulation of ductus arteriosus closure", "d": ["Any process that activates or increases the frequency, rate or extent of ductus arteriosus closure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901551", "l": "negative regulation of endothelial cell development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016544", "l": "male courtship behavior, tapping to detect pheromone", "d": ["The process during courtship where the male insect taps the female with his frontal leg. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902559", "l": "3'-phospho-5'-adenylyl sulfate transmembrane transport", "d": ["The process in which 3'-phospho-5'-adenylyl sulfate is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031161", "l": "phosphatidylinositol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0099633", "l": "protein localization to postsynaptic specialization membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. post synaptic density)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0039524", "l": "suppression by virus of host mRNA processing", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of mRNA processing in the host cell. mRNA processing is the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061374", "l": "mammillothalamic axonal tract development", "d": ["The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000485", "l": "cleavage between 2S rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage between the LSU-rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903895", "l": "negative regulation of IRE1-mediated unfolded protein response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the IRE1-mediated unfolded protein response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032526", "l": "response to retinoic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018299", "l": "iron incorporation into the Rieske iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide", "d": ["The incorporation of iron into a Rieske 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.744066580938323", "identifiers": [{"i": "GO:0042446", "l": "hormone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904317", "l": "cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:2000449", "l": "regulation of CD8-positive, alpha-beta T cell extravasation", "d": ["Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0061318", "l": "renal filtration cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051687", "l": "maintenance of spindle location", "d": ["Any process in which the spindle is maintained in a specific location within a cell and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035343", "l": "negative regulation of inosine transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071107", "l": "response to parathyroid hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903751", "l": "negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.565791298371025", "identifiers": [{"i": "GO:0006814", "l": "sodium ion transport", "d": ["The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051844", "l": "translocation of peptides or proteins into symbiont", "d": ["The directed movement of peptides or proteins produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046180", "l": "ketogluconate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097210", "l": "response to gonadotropin-releasing hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061128", "l": "positive regulation of chemotaxis to cAMP by DIF-2", "d": ["Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0017004", "l": "cytochrome complex assembly", "d": ["The aggregation, arrangement and bonding together of a cytochrome complex. A cytochrome complex is a protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905264", "l": "blasticidin S metabolic process", "d": ["The chemical reactions and pathways involving blasticidin S."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.594043123901756", "identifiers": [{"i": "GO:0042742", "l": "defense response to bacterium", "d": ["Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045337", "l": "farnesyl diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of farnesyl diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0045444", "l": "fat cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0019049", "l": "mitigation of host antiviral defense response", "d": ["A process by which a virus avoids or tolerates the effects of its host organism's defenses. Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900571", "l": "diorcinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diorcinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905652", "l": "negative regulation of artery morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097281", "l": "immune complex formation", "d": ["The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019523", "l": "L-idonate metabolic process", "d": ["The chemical reactions and pathways involving L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032922", "l": "circadian regulation of gene expression", "d": ["Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018217", "l": "peptidyl-aspartic acid phosphorylation", "d": ["The phosphorylation of peptidyl-aspartic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070309", "l": "lens fiber cell morphogenesis", "d": ["The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "31.917360466936852", "identifiers": [{"i": "GO:0009653", "l": "anatomical structure morphogenesis", "d": ["The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044593", "l": "iron-sulfur-molybdenum cofactor assembly", "d": ["The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036528", "l": "peptidyl-lysine deglycation", "d": ["The removal of a sugar or dicarbonyl from a lysine residue of a glycated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901107", "l": "granaticin metabolic process", "d": ["The chemical reactions and pathways involving granaticin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0009124", "l": "nucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035172", "l": "hemocyte proliferation", "d": ["The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1904994", "l": "regulation of leukocyte adhesion to vascular endothelial cell", "d": ["Any process that modulates the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071788", "l": "endoplasmic reticulum tubular network maintenance", "d": ["The organization process that preserves the endoplasmic reticulum (ER) tubular network in a stable functional or structural state. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0072678", "l": "T cell migration", "d": ["The movement of a T cell within or between different tissues and organs of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019580", "l": "galactarate metabolic process", "d": ["The chemical reactions and pathways involving galactarate, an anion of galactaric acid, the meso-aldaric acid derived from both D- and L-galactose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902890", "l": "regulation of root hair elongation", "d": ["Any process that modulates the frequency, rate or extent of root hair elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090239", "l": "regulation of histone H4 acetylation", "d": ["Any process that modulates the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051826", "l": "negative regulation of synapse structural plasticity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of synapse structural plasticity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035505", "l": "positive regulation of myosin light chain kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of myosin light chain kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035157", "l": "negative regulation of fusion cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from adopting a fusion cell fate. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900898", "l": "positive regulation of heptadecane biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of heptadecane biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060371", "l": "regulation of atrial cardiac muscle cell membrane depolarization", "d": ["Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in an atrial cardiomyocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0035108", "l": "limb morphogenesis", "d": ["The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0090698", "l": "post-embryonic plant morphogenesis", "d": ["The process, occurring after plant embryonic development, by which anatomical structures are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060922", "l": "atrioventricular node cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032747", "l": "positive regulation of interleukin-23 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-23 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904784", "l": "NLRP1 inflammasome complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a NLRP1 inflammasome complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905028", "l": "negative regulation of membrane depolarization during AV node cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during AV node cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000360", "l": "negative regulation of binding of sperm to zona pellucida", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of binding of sperm to the zona pellucida."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905956", "l": "positive regulation of endothelial tube morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045771", "l": "negative regulation of autophagosome size", "d": ["Any process that reduces autophagosome size."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905367", "l": "positive regulation of intralumenal vesicle formation", "d": ["Any process that activates or increases the frequency, rate or extent of intralumenal vesicle formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0002693", "l": "positive regulation of cellular extravasation", "d": ["Any process that activates or increases the frequency, rate, or extent of cellular extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002290", "l": "gamma-delta T cell activation involved in immune response", "d": ["The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000727", "l": "positive regulation of cardiac muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002261", "l": "mucosal lymphocyte homeostasis", "d": ["The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within the mucosal tissue of an organism is stable over time in the absence of an outside stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905257", "l": "positive regulation of RNA binding transcription factor activity", "d": ["Any process that activates or increases the frequency, rate or extent of RNA binding transcription factor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002646", "l": "regulation of central tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of central tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900240", "l": "negative regulation of phenotypic switching", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phenotypic switching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0021932", "l": "hindbrain radial glia guided cell migration", "d": ["The radially directed movement of a cell along radial glial cells in the hindbrain. Radial migration refers to a directed movement from the internal ventricular area to the outer surface of the hindbrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.468544520863134", "identifiers": [{"i": "GO:0061215", "l": "mesonephric nephron development", "d": ["The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000639", "l": "negative regulation of SREBP signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046335", "l": "ethanolamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0070590", "l": "spore wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a spore wall. A spore wall is the specialized cell wall lying outside the cell membrane of a spore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032716", "l": "negative regulation of interleukin-7 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-7 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070951", "l": "regulation of neutrophil mediated killing of gram-negative bacterium", "d": ["Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-negative bacterium, the directed killing of a gram-negative bacterium by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "51.424150156364647", "identifiers": [{"i": "GO:0009607", "l": "response to biotic stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901095", "l": "positive regulation of protein homotetramerization", "d": ["Any process that activates or increases the frequency, rate or extent of protein homotetramerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0048799", "l": "animal organ maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.505763639973935", "identifiers": [{"i": "GO:0048285", "l": "organelle fission", "d": ["The creation of two or more organelles by division of one organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903495", "l": "cellular response to dehydroepiandrosterone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071578", "l": "zinc ion import across plasma membrane", "d": ["The directed movement of zinc(2+) ions from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021685", "l": "cerebellar granular layer structural organization", "d": ["The process that contributes to the act of creating the structural organization of the cerebellar granule layer. This process pertains to the physical shaping of a rudimentary structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045954", "l": "positive regulation of natural killer cell mediated cytotoxicity", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032703", "l": "negative regulation of interleukin-2 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901151", "l": "vistamycin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of vistamycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.320432051819239", "identifiers": [{"i": "GO:0010565", "l": "regulation of cellular ketone metabolic process", "d": ["Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0000751", "l": "mitotic cell cycle G1 arrest in response to pheromone", "d": ["The cell cycle regulatory process in which the mitotic cell cycle is halted during G1 as a result of a pheromone stimulus. An example of this process is found in Saccharomyces cerevisiae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002330", "l": "pre-B cell receptor expression", "d": ["The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, starting with the recombination of an immunuglobulin heavy chain locus, including expression of the surrogate light chain, the association of the surrogate light chain with the heavy chain, and expression of the complete pre-B cell receptor on the cell surface. pre-B cell receptor expression is a key checkpoint in the transition of pro-B cell to pre-B cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019628", "l": "urate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of urate, the anion of uric acid, 2,6,8-trioxypurine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901337", "l": "thioester transport", "d": ["The directed movement of a thioester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0048813", "l": "dendrite morphogenesis", "d": ["The process in which the anatomical structures of a dendrite are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006034", "l": "cuticle chitin metabolic process", "d": ["The chemical reactions and pathways involving cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0075214", "l": "spore encystment", "d": ["The physiological, developmental and morphological changes that occur in a symbiont spore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060576", "l": "intestinal epithelial cell development", "d": ["The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010096", "l": "specification of sepal identity", "d": ["The process in which a floral organ primordium acquires sepal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:1901722", "l": "regulation of cell proliferation involved in kidney development", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000313", "l": "regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation", "d": ["Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000395", "l": "regulation of ubiquitin-dependent endocytosis", "d": ["Any process that modulates the frequency, rate or extent of ubiquitin-dependent endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0120191", "l": "negative regulation of termination of RNA polymerase II transcription", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0042364", "l": "water-soluble vitamin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901740", "l": "negative regulation of myoblast fusion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myoblast fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0003214", "l": "cardiac left ventricle morphogenesis", "d": ["The process in which the left cardiac ventricle is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.128151444246335", "identifiers": [{"i": "GO:0030182", "l": "neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902082", "l": "positive regulation of calcium ion import into sarcoplasmic reticulum", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0042908", "l": "xenobiotic transport", "d": ["The directed movement of a xenobiotic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042442", "l": "melatonin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0019073", "l": "viral DNA genome packaging", "d": ["The packing of viral DNA into a capsid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036234", "l": "deglucuronidation", "d": ["The removal of glucuronic acid from a conjugated substrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "33.326644217189383", "identifiers": [{"i": "GO:0007369", "l": "gastrulation", "d": ["A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018969", "l": "thiocyanate metabolic process", "d": ["The chemical reactions and pathways involving thiocyanate, the anion of thiocyanic acid, a toxic cyanide derivative commonly formed as a by-product in the production of gas for fuel, coke, and substances for chemical industries."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032966", "l": "negative regulation of collagen biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905785", "l": "negative regulation of anaphase-promoting complex-dependent catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1905544", "l": "L-methionine import across plasma membrane", "d": ["The directed movement of L-methionine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902641", "l": "regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process", "d": ["Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0009111", "l": "vitamin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990927", "l": "calcium ion regulated lysosome exocytosis", "d": ["The process of secretion by a cell that results in the release of intracellular molecules contained within a lysosome by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051365", "l": "cellular response to potassium ion starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of potassium ions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071382", "l": "cellular response to prostaglandin I stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0098815", "l": "modulation of excitatory postsynaptic potential", "d": ["Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062093", "l": "lysophagy", "d": ["The selective autophagy process in which a damaged lysosome is degraded by macroautophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0061323", "l": "cell proliferation involved in heart morphogenesis", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019537", "l": "vibriobactin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of vibriobactin, the major siderophore produced by Vibrio cholerae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003243", "l": "circumferential growth involved in left ventricle morphogenesis", "d": ["The morphogenetic growth in which the left ventricle grows expanding its external boundary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0050904", "l": "diapedesis", "d": ["The passage of a leukocyte between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021573", "l": "rhombomere 7 development", "d": ["The process whose specific outcome is the progression of rhombomere 7 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904106", "l": "protein localization to microvillus", "d": ["A process in which a protein is transported to, or maintained in, a location within a microvillus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010668", "l": "ectodermal cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060599", "l": "lateral sprouting involved in mammary gland duct morphogenesis", "d": ["The process in which a branch forms along the side of a mammary duct."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030643", "l": "intracellular phosphate ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of phosphate ions within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0048508", "l": "embryonic meristem development", "d": ["The process whose specific outcome is the progression of the embryonic meristem over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.569439710577498", "identifiers": [{"i": "GO:0002228", "l": "natural killer cell mediated immunity", "d": ["The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006169", "l": "adenosine salvage", "d": ["Any process that generates adenosine, adenine riboside, from derivatives of it without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900798", "l": "cordyol C catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cordyol C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0006270", "l": "DNA replication initiation", "d": ["The process in which DNA-dependent DNA replication is started; it begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, followed by DNA unwinding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071659", "l": "negative regulation of IP-10 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of IP-10."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0009746", "l": "response to hexose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905155", "l": "positive regulation of membrane invagination", "d": ["Any process that activates or increases the frequency, rate or extent of membrane invagination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061646", "l": "positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization", "d": ["Any process that activates or increases the frequency, rate or extent of glutamate secretion in response to membrane depolarization, where glutamate acts as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048139", "l": "female germ-line cyst encapsulation", "d": ["Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the female gonad."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015753", "l": "D-xylose transmembrane transport", "d": ["The process in which D-xylose is transported across a lipid bilayer, from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018185", "l": "poly-N-methyl-propylamination", "d": ["The modification of peptidyl-lysine by the addition of an N6-propylamino and of propylmethylamino units, forming N6-(propylamino-poly(propylmethylamino)-propyldimethylamine)-L-lysine, typical of the silicate binding protein silaffin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044564", "l": "envenomation resulting in occlusion of the pore of voltage-gated potassium channel in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant blocking of a voltage-gated potassium channel, inhibiting the pore's activity, in the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070100", "l": "negative regulation of chemokine-mediated signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of a chemokine-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0014823", "l": "response to activity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018154", "l": "peptide cross-linking via (2R,6R)-lanthionine", "d": ["The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of (2R,6R)-lanthionine (L-lanthionine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045106", "l": "intermediate filament depolymerization", "d": ["Disassembly of intermediate filaments by the removal of component monomers from a filament."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097055", "l": "agmatine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of agmatine ((4-aminobutyl)guanidine, NH2-CH2-CH2-CH2-CH2-NH-C(-NH2)(=NH)). Agmatine is the decarboxylation product of the amino acid arginine and is an intermediate in polyamine biosynthesis. It is synthesized in the brain, stored in synaptic vesicles, accumulated by uptake, released by membrane depolarization, and inactivated by agmatinase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048936", "l": "peripheral nervous system neuron axonogenesis", "d": ["Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045304", "l": "regulation of establishment of competence for transformation", "d": ["Any process that modulates the frequency, rate or extent of the process in which a cell becomes able to take up and incorporate extracellular DNA into its genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071328", "l": "cellular response to maltose stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046155", "l": "rhodopsin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903498", "l": "bundle sheath cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a bundle sheath cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036245", "l": "cellular response to menadione", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0033273", "l": "response to vitamin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0033034", "l": "positive regulation of myeloid cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.544378474006969", "identifiers": [{"i": "GO:0030855", "l": "epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002341", "l": "central B cell anergy", "d": ["Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in B cells in the bone marrow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019337", "l": "tetrachloroethylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tetrachloroethylene, a derivative of ethene with the hydrogen atoms replaced by chlorines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085019", "l": "formation of tubovesicular network for nutrient acquisition", "d": ["The assembly of a symbiont-induced complex organelle that comprises of multiple protein and lipid domains for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905046", "l": "positive regulation of Schwann cell proliferation involved in axon regeneration", "d": ["Any process that activates or increases the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900747", "l": "negative regulation of vascular endothelial growth factor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010754", "l": "negative regulation of cGMP-mediated signaling", "d": ["Any process that decreases the rate, frequency or extent of cGMP-mediated signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006748", "l": "lipoamide metabolic process", "d": ["The chemical reactions and pathways involving lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006011", "l": "UDP-glucose metabolic process", "d": ["The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0140962", "l": "multicellular organismal-level chemical homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of a chemical within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060208", "l": "proestrus", "d": ["The estrous cycle phase in which there is heightened follicular activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002391", "l": "platelet activating factor production involved in inflammatory response", "d": ["The synthesis or release of platelet activating factor following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0043301", "l": "negative regulation of leukocyte degranulation", "d": ["Any process that stops, prevents, or reduces the rate of leukocyte degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000166", "l": "negative regulation of planar cell polarity pathway involved in pericardium morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.369316165162914", "identifiers": [{"i": "GO:0009100", "l": "glycoprotein metabolic process", "d": ["The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007250", "l": "activation of NF-kappaB-inducing kinase activity", "d": ["The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009455", "l": "redox taxis", "d": ["The directed movement of a motile cell or organism in response to redox potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021745", "l": "nucleus ambiguus development", "d": ["The process whose specific outcome is the progression of the nucleus ambiguus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0003022", "l": "detection of pH by chemoreceptor signaling", "d": ["The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046449", "l": "creatinine metabolic process", "d": ["The chemical reactions and pathways involving creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050496", "l": "peptidyl-L-glutamyl 5-omega-hydroxyceramide ester biosynthetic process from peptidyl-glutamine", "d": ["The modification of peptidyl-glutamine residues by deamidation and esterification with omega-hydroxyceramide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900483", "l": "regulation of protein targeting to vacuolar membrane", "d": ["Any process that modulates the frequency, rate or extent of protein targeting to vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904633", "l": "regulation of podocyte apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060087", "l": "relaxation of vascular associated smooth muscle", "d": ["A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0010934", "l": "macrophage cytokine production", "d": ["The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0046755", "l": "viral budding", "d": ["A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090403", "l": "oxidative stress-induced premature senescence", "d": ["A cellular senescence process associated with the dismantling of a cell as a response to oxidative stress, e.g. high levels of reactive oxygen species, such as superoxide anions, hydrogen peroxide, and hydroxyl radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002231", "l": "detection of oomycetes", "d": ["The series of events in which a stimulus from an oomycetes is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903570", "l": "regulation of protein kinase D signaling", "d": ["Any process that modulates the frequency, rate or extent of protein kinase D signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043693", "l": "monoterpene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monoterpenes, terpenes with a C10 structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006057", "l": "mannoprotein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a mannoprotein, a protein that contains covalently bound mannose residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045593", "l": "negative regulation of cumulus cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ovarian cumulus cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032332", "l": "positive regulation of chondrocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070714", "l": "RNA guanosine-uridine insertion", "d": ["The modification of an RNA molecule by insertion of an guanosine-uridine insertion dinucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120258", "l": "peptidyl-threonine O-acetylation", "d": ["The acetylation of peptidyl-threonine to form peptidyl-O-acetyl-L-threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0015807", "l": "L-amino acid transport", "d": ["The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903418", "l": "protein localization to plasma membrane of cell tip", "d": ["A process in which a protein is transported to, or maintained in, a location within a plasma membrane of cell tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098036", "l": "viral DNA genome packaging, 3' extended cos packaging", "d": ["The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 3' protruding ends."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0006839", "l": "mitochondrial transport", "d": ["Transport of substances into, out of or within a mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150070", "l": "regulation of arginase activity", "d": ["Any process that modulates the frequency, rate or extent of arginase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002087", "l": "regulation of respiratory gaseous exchange by nervous system process", "d": ["A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021640", "l": "trochlear nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the trochlear nerve to attain its fully functional state. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060080", "l": "inhibitory postsynaptic potential", "d": ["A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0035050", "l": "embryonic heart tube development", "d": ["The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903070", "l": "negative regulation of ER-associated ubiquitin-dependent protein catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990790", "l": "response to glial cell derived neurotrophic factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0043217", "l": "myelin maintenance", "d": ["The process of preserving the structure and function of mature myelin. This includes maintaining the compact structure of myelin necessary for its electrical insulating characteristics as well as the structure of non-compact regions such as Schmidt-Lantermann clefts and paranodal loops. This does not include processes responsible for maintaining the nodes of Ranvier, which are not part of the myelin sheath."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.240853996207278", "identifiers": [{"i": "GO:0008203", "l": "cholesterol metabolic process", "d": ["The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0099623", "l": "regulation of cardiac muscle cell membrane repolarization", "d": ["Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018533", "l": "peptidyl-cysteine acetylation", "d": ["The acetylation of peptidyl-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1904271", "l": "L-proline import across plasma membrane", "d": ["The directed movement of L-proline from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902464", "l": "regulation of histone H3-K27 trimethylation", "d": ["Any process that modulates the frequency, rate or extent of histone H3-K27 trimethylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046443", "l": "FAD metabolic process", "d": ["The chemical reactions and pathways involving FAD, the oxidized form of flavin adenine dinucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.071082486141265", "identifiers": [{"i": "GO:0042546", "l": "cell wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall. Includes biosynthesis of constituent macromolecules, such as proteins and polysaccharides, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. A cell wall is the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090390", "l": "phagosome acidification involved in apoptotic cell clearance", "d": ["Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion, and occurs as a part of apoptotic cell clearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905275", "l": "Rohon-Beard neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a Rohon-Beard neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031289", "l": "actin phosphorylation", "d": ["The transfer of one or more phosphate groups to an actin molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903575", "l": "cornified envelope assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a cornified envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0007293", "l": "germarium-derived egg chamber formation", "d": ["Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0060042", "l": "retina morphogenesis in camera-type eye", "d": ["The process in which the anatomical structure of the retina is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900283", "l": "negative regulation of cellobiose catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0032892", "l": "positive regulation of organic acid transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034589", "l": "hydroxyproline transport", "d": ["The directed movement of hydroxyproline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061704", "l": "glycolytic process from sucrose", "d": ["The chemical reactions and pathways resulting in the breakdown of a sucrose into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051163", "l": "D-arabitol metabolic process", "d": ["The chemical reactions and pathways involving D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061078", "l": "positive regulation of prostaglandin secretion involved in immune response", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046441", "l": "D-lysine metabolic process", "d": ["The chemical reactions and pathways involving D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048633", "l": "positive regulation of skeletal muscle tissue growth", "d": ["Any process that activates, maintains or increases the rate of skeletal muscle growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061286", "l": "mesonephric capsule morphogenesis", "d": ["The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900223", "l": "positive regulation of amyloid-beta clearance", "d": ["Any process that activates or increases the frequency, rate or extent of amyloid-beta clearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071623", "l": "negative regulation of granulocyte chemotaxis", "d": ["Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0035214", "l": "eye-antennal disc development", "d": ["Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0051384", "l": "response to glucocorticoid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044529", "l": "regulation of mitochondrial rRNA stability", "d": ["Any process that modulates the propensity of mitochondrial rRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial rRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019381", "l": "atrazine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900105", "l": "negative regulation of hyaluranon cable assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hyaluranon cable assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900420", "l": "negative regulation of cellular alcohol catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular alcohol catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160023", "l": "sneeze reflex", "d": ["A reflex process that expels air forcibly from the mouth and nose in an explosive, spasmodic involuntary action resulting chiefly from irritation of the nasal mucous membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905183", "l": "negative regulation of protein serine/threonine phosphatase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein serine/threonine phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001175", "l": "transcriptional start site selection at RNA polymerase III promoter", "d": ["Any process involved in the selection of the specific location within the template strand of an RNA polymerase III promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:1904427", "l": "positive regulation of calcium ion transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006116", "l": "NADH oxidation", "d": ["A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD+."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0051150", "l": "regulation of smooth muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032278", "l": "positive regulation of gonadotropin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900607", "l": "tensidol B catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tensidol B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0015840", "l": "urea transport", "d": ["The directed movement of urea into, out of or within the cell. Urea is the water-soluble compound H2N-CO-NH2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061889", "l": "negative regulation of astrocyte activation", "d": ["Any process that decreases the frequency, rate or extent of astrocyte activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.381173084437549", "identifiers": [{"i": "GO:0042157", "l": "lipoprotein metabolic process", "d": ["The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0086016", "l": "AV node cell action potential", "d": ["An action potential that occurs in an atrioventricular node cardiac muscle cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903360", "l": "protein localization to lateral cortical node", "d": ["A process in which a protein is transported to, or maintained in, a location within a lateral cortical node."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030327", "l": "prenylated protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of prenylated proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000950", "l": "branched-chain amino acid catabolic process to alcohol via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanol, 2-methylbutanol, or 2-methylpropanol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0009080", "l": "pyruvate family amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any amino acid that requires pyruvate for its synthesis, e.g. alanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060365", "l": "coronal suture morphogenesis", "d": ["The process in which the coronal suture is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046363", "l": "ribitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0043056", "l": "forward locomotion", "d": ["Anterior movement of an organism, following the direction of the head of the animal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0019579", "l": "aldaric acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010132", "l": "dhurrin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dhurrin, a cyanogenic glucoside which functions as a plant defense compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051889", "l": "negative regulation of timing of exogen", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061586", "l": "positive regulation of transcription by transcription factor localization", "d": ["Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070712", "l": "RNA cytidine-uridine insertion", "d": ["The modification of an RNA molecule by insertion of an cytidine-uridine dinucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002236", "l": "detection of misfolded protein", "d": ["The series of events in which a misfolded protein stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0048334", "l": "regulation of mesodermal cell fate determination", "d": ["Any process that modulates the frequency, rate or extent of mesoderm cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061721", "l": "6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)", "d": ["The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfopropanediol(1-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903680", "l": "acinar cell of sebaceous gland differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an acinar cell of sebaceous gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002829", "l": "negative regulation of type 2 immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903663", "l": "L-altrarate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-altrarate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:1900674", "l": "olefin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of olefin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.706877558974412", "identifiers": [{"i": "GO:0002831", "l": "regulation of response to biotic stimulus", "d": ["Any process that modulates the frequency, rate, or extent of a response to biotic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901116", "l": "cephamycin C metabolic process", "d": ["The chemical reactions and pathways involving cephamycin C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0039697", "l": "negative stranded viral RNA transcription", "d": ["A viral transcription process that uses negative stranded (-) single stranded (ss) RNA as a template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120312", "l": "ciliary basal body segregation", "d": ["The process in which the duplicated basal bodies migrate in pairs to the mitotic poles of the nucleus and results in equal distribution in the daughter cells. Ciliary basal body segregation ensures inheritance of the duplicated mitochondrial DNA to the two daughter cells in the Trypanosoma parasites."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035128", "l": "post-embryonic forelimb morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070262", "l": "peptidyl-serine dephosphorylation", "d": ["The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045219", "l": "regulation of FasL production", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060132", "l": "prolactin secreting cell development", "d": ["The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:2001185", "l": "regulation of CD8-positive, alpha-beta T cell activation", "d": ["Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0090609", "l": "single-species submerged biofilm formation", "d": ["A process in which planktonically growing microorganisms of the same species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080181", "l": "lateral root branching", "d": ["Any process involved in the formation of branches in lateral roots."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0045944", "l": "positive regulation of transcription by RNA polymerase II", "d": ["Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.582174935760108", "identifiers": [{"i": "GO:0140029", "l": "exocytic process", "d": ["The cellular processes that contribute to exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016267", "l": "O-glycan processing, core 1", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-(1->3)-GalNAc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046896", "l": "N-terminal peptidyl-leucine methylation", "d": ["The methylation of the N-terminal leucine of proteins to form the derivative N-methyl-L-leucine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0086070", "l": "SA node cell to atrial cardiac muscle cell communication", "d": ["The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0099175", "l": "regulation of postsynapse organization", "d": ["Any process that modulates the physical form of a postsynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040027", "l": "negative regulation of vulval development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0070944", "l": "neutrophil-mediated killing of bacterium", "d": ["The directed killing of a bacterium by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0033037", "l": "polysaccharide localization", "d": ["Any process in which a polysaccharide is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048479", "l": "style development", "d": ["The process whose specific outcome is the progression of the style over time, from its formation to the mature structure. The style is an elongated part of a carpel, or group of fused carpels, and it lies between the ovary and the stigma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0042822", "l": "pyridoxal phosphate metabolic process", "d": ["The chemical reactions and pathways involving pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0032887", "l": "regulation of spindle elongation", "d": ["Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032423", "l": "regulation of mismatch repair", "d": ["Any process that modulates the frequency, rate or extent of mismatch repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0007252", "l": "I-kappaB phosphorylation", "d": ["The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048684", "l": "positive regulation of collateral sprouting of intact axon in response to injury", "d": ["Any process that activates, maintains or increases the rate of collateral sprouting of an intact axon as a result of injury to an axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.170973648324292", "identifiers": [{"i": "GO:1902105", "l": "regulation of leukocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of leukocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072085", "l": "specification of connecting tubule identity", "d": ["The process in which the connecting tubule of the kidney nephron acquires its identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140244", "l": "regulation of translation at presynapse", "d": ["Any process that regulates translation occurring at the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035352", "l": "NAD transmembrane transport", "d": ["The process in which a nicotinamide adenine dinucleotide is transported across a membrane; transport may be of either the oxidized form, NAD, or the reduced form, NADH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.870242003977111", "identifiers": [{"i": "GO:1901605", "l": "alpha-amino acid metabolic process", "d": ["The chemical reactions and pathways involving an alpha-amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006077", "l": "(1->6)-beta-D-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->6)-beta-D-glucans, compounds composed of glucose residues linked by (1->6)-beta-D-glucosidic bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001715", "l": "ectodermal cell fate specification", "d": ["The cell fate determination process that results in a cell becoming becomes capable of differentiating autonomously into an ectoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.003741351937961", "identifiers": [{"i": "GO:0001736", "l": "establishment of planar polarity", "d": ["Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0008064", "l": "regulation of actin polymerization or depolymerization", "d": ["Any process that modulates the frequency, rate or extent of the assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1904353", "l": "regulation of telomere capping", "d": ["Any process that modulates the frequency, rate or extent of telomere capping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018190", "l": "protein octanoylation", "d": ["The modification of a protein amino acid by formation of an ester or amide with octanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006673", "l": "inositol phosphoceramide metabolic process", "d": ["The chemical reactions and pathways involving inositol phosphoceramides, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046166", "l": "glyceraldehyde-3-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glyceraldehyde-3-phosphate, an important intermediate in glycolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046339", "l": "diacylglycerol metabolic process", "d": ["The chemical reactions and pathways involving diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019445", "l": "tyrosine catabolic process to fumarate", "d": ["The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including fumarate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0002294", "l": "CD4-positive, alpha-beta T cell differentiation involved in immune response", "d": ["The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045167", "l": "asymmetric protein localization involved in cell fate determination", "d": ["Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097380", "l": "dorsal spinal cord interneuron anterior axon guidance", "d": ["The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the anterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075043", "l": "melanization of appressorium wall", "d": ["The process in which melanin is produced in the appressorium of the symbiont. Melanization of the appressorium increases turgor pressure in the appressorium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990968", "l": "modulation by host of RNA binding by virus", "d": ["A process in which a host organism modulates the frequency, rate or extent of a viral gene product binding to RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902198", "l": "3-methylbut-2-enoyl-CoA(4-) metabolic process", "d": ["The chemical reactions and pathways involving 3-methylbut-2-enoyl-CoA(4-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001027", "l": "negative regulation of endothelial cell chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110083", "l": "positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050946", "l": "positive regulation of xanthophore differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of xanthophore differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.009127879491089", "identifiers": [{"i": "GO:0048608", "l": "reproductive structure development", "d": ["The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031642", "l": "negative regulation of myelination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072257", "l": "metanephric nephron tubule epithelial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0150178", "l": "regulation of phosphatidylserine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylserine metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106119", "l": "negative regulation of sterol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a sterol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002404", "l": "antigen sampling in mucosal-associated lymphoid tissue", "d": ["The process of apical-to-basolateral delivery of soluble and particulate antigens to underlying mucosal-associated lymphoid tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061093", "l": "negative regulation of phospholipid translocation", "d": ["Any process that decreases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042308", "l": "negative regulation of protein import into nucleus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035913", "l": "ventral aorta morphogenesis", "d": ["The process in which the anatomical structures of the ventral aorta are generated and organized. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905719", "l": "protein localization to perinuclear region of cytoplasm", "d": ["A process in which a protein is transported to, or maintained in, a location within the perinuclear region of the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0072081", "l": "specification of nephron tubule identity", "d": ["The process in which the tubules arranged along the proximal/distal axis of the nephron acquire their identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0010965", "l": "regulation of mitotic sister chromatid separation", "d": ["Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905042", "l": "negative regulation of epithelium regeneration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epithelium regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046111", "l": "xanthine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0050685", "l": "positive regulation of mRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042355", "l": "L-fucose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905800", "l": "negative regulation of intraciliary retrograde transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary retrograde transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072064", "l": "long descending thin limb development", "d": ["The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0048319", "l": "axial mesoderm morphogenesis", "d": ["The process in which the anatomical structures of the axial mesoderm are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.871876592857262", "identifiers": [{"i": "GO:0051924", "l": "regulation of calcium ion transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015969", "l": "guanosine tetraphosphate metabolic process", "d": ["The chemical reactions and pathways involving guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901744", "l": "2-deoxystreptamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 2-deoxystreptamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034266", "l": "isopentenyl adenine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the cytokinin 6-isopentenyladenine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034489", "l": "neutral amino acid transmembrane export from vacuole", "d": ["The directed movement of neutral amino acids out of the vacuole, across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006539", "l": "glutamate catabolic process via 2-oxoglutarate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxoglutarate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043314", "l": "negative regulation of neutrophil degranulation", "d": ["Any process that stops, prevents, or reduces the rate of neutrophil degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0106004", "l": "tRNA (guanine-N7)-methylation", "d": ["The process whereby a guanine in a tRNA is methylated at the N7 position of guanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901262", "l": "negative regulation of sorocarp spore cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sorocarp spore cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0060291", "l": "long-term synaptic potentiation", "d": ["A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904787", "l": "positive regulation of asymmetric protein localization involved in cell fate determination", "d": ["Any process that activates or increases the frequency, rate or extent of asymmetric protein localization involved in cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003288", "l": "ventricular septum intermedium morphogenesis", "d": ["The developmental process in which a ventricular septum intermedium is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036179", "l": "osteoclast maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990375", "l": "baculum development", "d": ["The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038002", "l": "endocrine signaling", "d": ["The transfer of information from one cell to another, where an endocrine hormone is transported from the signal-producing cell to the receiving cell via the circulatory system (via blood, lymph or cerebrospinal fluid). The signaling cell and the receiving cell are often distant to each other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.465174152298118", "identifiers": [{"i": "GO:1902644", "l": "tertiary alcohol metabolic process", "d": ["The chemical reactions and pathways involving tertiary alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061368", "l": "behavioral response to formalin induced pain", "d": ["Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0052699", "l": "ergothioneine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904235", "l": "regulation of substrate-dependent cell migration, cell attachment to substrate", "d": ["Any process that modulates the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0099639", "l": "neurotransmitter receptor transport, endosome to plasma membrane", "d": ["The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075196", "l": "adhesion of symbiont haustorium mother cell to host", "d": ["The attachment of a haustorium mother cell of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0009132", "l": "nucleoside diphosphate metabolic process", "d": ["The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071589", "l": "pyridine nucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any pyridine nucleoside, one of a family of organic molecules consisting of a pyridine base covalently bonded to a sugar, usually ribose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0099636", "l": "cytoplasmic streaming", "d": ["The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140884", "l": "suppression by virus of host type II interferon-mediated signaling pathway", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type II interferon-mediated signaling in the host organism. Type II interferon is also known as interferon-gamma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905789", "l": "positive regulation of detection of mechanical stimulus involved in sensory perception of touch", "d": ["Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0061242", "l": "mesonephric nephron tubule development", "d": ["The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018234", "l": "peptide cross-linking via 3'-(S-L-cysteinyl)-L-tyrosine", "d": ["The thioether cross-linking of a cysteine residue to a tyrosine residue to form 3'-(S-L-cysteinyl)-L-tyrosine, found in galactose oxidase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002630", "l": "positive regulation of proteolysis associated with antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048906", "l": "anterior lateral line neuromast support cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010361", "l": "regulation of anion channel activity by blue light", "d": ["Any process in which blue light modulates the frequency, rate or extent of anion channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903634", "l": "negative regulation of leucine-tRNA ligase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leucine-tRNA ligase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097105", "l": "presynaptic membrane assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061740", "l": "protein targeting to lysosome involved in chaperone-mediated autophagy", "d": ["The targeting of a protein to the lysosome process in which an input protein binds to a chaperone and subsequently to a lysosomal receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903544", "l": "response to butyrate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0032262", "l": "pyrimidine nucleotide salvage", "d": ["Any process which produces a pyrimidine nucleotide from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2000780", "l": "negative regulation of double-strand break repair", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902746", "l": "regulation of lens fiber cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of lens fiber cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090338", "l": "positive regulation of formin-nucleated actin cable assembly", "d": ["Any process that increases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046839", "l": "phospholipid dephosphorylation", "d": ["The process of removing one or more phosphate groups from a phosphorylated lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060634", "l": "regulation of 4,6-pyruvylated galactose residue biosynthetic process", "d": ["Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-(1->3)-. The galactose residue is part of a larger polysaccharide chain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048850", "l": "hypophysis morphogenesis", "d": ["The process in which the anatomical structures of the hypophysis are generated and organized. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000948", "l": "regulation of xyloglucan metabolic process", "d": ["Any process that modulates the frequency, rate or extent of xyloglucan metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071447", "l": "cellular response to hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002747", "l": "antigen processing and presentation following phagocytosis", "d": ["Antigen processing and presentation which is initiated by uptake of antigen via phagocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072050", "l": "S-shaped body morphogenesis", "d": ["The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0014724", "l": "regulation of twitch skeletal muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of twitch skeletal muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062133", "l": "negative regulation of L-glutamine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.569696769170775", "identifiers": [{"i": "GO:0009057", "l": "macromolecule catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032624", "l": "interleukin-20 production", "d": ["The appearance of interleukin-20 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072631", "l": "interleukin-29 production", "d": ["The appearance of interleukin-29 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031408", "l": "oxylipin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010288", "l": "response to lead ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000947", "l": "amino acid catabolic process to alcohol via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0097017", "l": "renal protein absorption", "d": ["A renal system process in which proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071388", "l": "cellular response to cortisone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032785", "l": "negative regulation of DNA-templated transcription, elongation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990799", "l": "mitochondrial tRNA wobble position uridine thiolation", "d": ["The process in which a uridine residue at position 34 in the anticodon of a mitochondrial tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070713", "l": "RNA guanosine-cytidine insertion", "d": ["The modification of an RNA molecule by insertion of an guanosine-cytidine dinucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055058", "l": "symmetric neuroblast division", "d": ["The process resulting in the physical partitioning and separation of a neuroblast into two equi-potent daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032754", "l": "positive regulation of interleukin-5 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-5 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007535", "l": "donor selection", "d": ["The process that determines which donor locus a cell uses, in preference to another, in mating type switching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0016074", "l": "sno(s)RNA metabolic process", "d": ["The chemical reactions and pathways involving snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1901020", "l": "negative regulation of calcium ion transmembrane transporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903056", "l": "regulation of melanosome organization", "d": ["Any process that modulates the frequency, rate or extent of melanosome organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003372", "l": "establishment or maintenance of cytoskeleton polarity involved in mesendodermal cell migration", "d": ["Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating mesendodermal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900102", "l": "negative regulation of endoplasmic reticulum unfolded protein response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum unfolded protein response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021654", "l": "rhombomere boundary formation", "d": ["The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075195", "l": "negative regulation of haustorium mother cell formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019802", "l": "cyclization of glutamine involved in intein-mediated protein splicing", "d": ["The cyclization of glutamine to yield an L-glutamimide residue at the C-terminus of an excised intein during protein splicing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071262", "l": "regulation of translational initiation in response to starvation", "d": ["Any process that modulates the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904120", "l": "positive regulation of otic vesicle morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of otic vesicle morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904758", "l": "protein localization to new growing cell tip", "d": ["A process in which a protein is transported to, or maintained in, a location within a new growing cell tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903358", "l": "regulation of Golgi organization", "d": ["Any process that modulates the frequency, rate or extent of Golgi organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.595701364683777", "identifiers": [{"i": "GO:0045595", "l": "regulation of cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035431", "l": "negative regulation of gluconate transmembrane transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006931", "l": "substrate-dependent cell migration, cell attachment to substrate", "d": ["The formation of adhesions that stabilize protrusions at the leading edge of a migrating cell; involves integrin activation, clustering, and the recruitment of structural and signaling components to nascent adhesions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0031000", "l": "response to caffeine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0035246", "l": "peptidyl-arginine N-methylation", "d": ["The addition of a methyl group onto a nitrogen atom of an arginine residue in a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0042701", "l": "progesterone secretion", "d": ["The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0090626", "l": "plant epidermis morphogenesis", "d": ["The process in which the anatomical structures of the plant epidermis are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0006298", "l": "mismatch repair", "d": ["A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014058", "l": "negative regulation of acetylcholine secretion, neurotransmission", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002840", "l": "regulation of T cell mediated immune response to tumor cell", "d": ["Any process that modulates the frequency, rate, or extent of a T cell mediated immune response to tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061939", "l": "c-di-GMP signaling", "d": ["Any process that mediates the transfer of information from one cell to another using c-di-GMP as the signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060207", "l": "diestrus", "d": ["The estrous cycle phase which is a period of sexual quiescence and represents the phase of the mature corpus luteum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0006706", "l": "steroid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061211", "l": "mesonephric collecting duct development", "d": ["The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000387", "l": "spliceosomal snRNP assembly", "d": ["The aggregation, arrangement and bonding together of one or more snRNA and multiple protein components to form a ribonucleoprotein complex that is involved in formation of the spliceosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0061988", "l": "karyosome formation", "d": ["The chromosome organization process in which meiotic chromosomes in the germ cell nucleus cluster together to form a compact spherical structure called the karyosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001168", "l": "positive regulation of histone H2B ubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of histone H2B ubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990491", "l": "methane biosynthetic process from methanol and hydrogen", "d": ["The chemical reactions and pathways resulting in the formation of methane from methanol and hydrogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018968", "l": "tetrahydrofuran metabolic process", "d": ["The chemical reactions and pathways involving tetrahydrofuran, a cyclic 4 carbon ether. It is one of the most polar ethers and is a widely used solvent for polar reagents. Since THF is very soluble in water and has a relatively low boiling point, significant amounts are often released into the environment, causing contamination problems."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061442", "l": "cardiac muscle cell fate determination", "d": ["The process involved in cardiac muscle cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051284", "l": "positive regulation of sequestering of calcium ion", "d": ["Any process that activates or increases the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905746", "l": "positive regulation of mRNA cis splicing, via spliceosome", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA cis splicing, via spliceosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000714", "l": "meiotic strand displacement", "d": ["The cell cycle process in which the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA is rejected. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules. This occurs during meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1901913", "l": "regulation of capsule organization", "d": ["Any process that modulates the frequency, rate or extent of capsule organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900499", "l": "positive regulation of butyryl-CoA catabolic process to butanol", "d": ["Any process that activates or increases the frequency, rate or extent of butyryl-CoA catabolic process to butanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0032945", "l": "negative regulation of mononuclear cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902602", "l": "aluminum ion transmembrane transport", "d": ["The process in which an aluminium ion is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061623", "l": "glycolytic process from galactose", "d": ["The chemical reactions and pathways resulting in the breakdown of galactose into pyruvate, with the concomitant production of a small amount of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045680", "l": "negative regulation of R8 cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of R8 cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006709", "l": "progesterone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905946", "l": "negative regulation of response to calcium ion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to calcium ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.161881760686384", "identifiers": [{"i": "GO:0048663", "l": "neuron fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043375", "l": "CD8-positive, alpha-beta T cell lineage commitment", "d": ["The process in which an immature T cell becomes committed to becoming a CD8-positive, alpha-beta T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140330", "l": "xenobiotic detoxification by transmembrane export across the cell outer membrane", "d": ["A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell through the outer membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000349", "l": "generation of catalytic spliceosome for first transesterification step", "d": ["Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902036", "l": "regulation of hematopoietic stem cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000820", "l": "negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation", "d": ["Any negative regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002091", "l": "negative regulation of receptor internalization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of receptor internalization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060780", "l": "intercalary leaflet morphogenesis", "d": ["The process in which the intercalary leaflet attains its shape. An intercalary leaflet is a leaflet that develops between primary leaflets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0045638", "l": "negative regulation of myeloid cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0036303", "l": "lymph vessel morphogenesis", "d": ["The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0098704", "l": "carbohydrate import across plasma membrane", "d": ["The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1901799", "l": "negative regulation of proteasomal protein catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of proteasomal protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0006888", "l": "endoplasmic reticulum to Golgi vesicle-mediated transport", "d": ["The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000463", "l": "positive regulation of excitatory postsynaptic potential", "d": ["Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019334", "l": "p-cymene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000375", "l": "negative regulation of oxygen metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140193", "l": "regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process", "d": ["Any process that modulates the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903662", "l": "L-altrarate metabolic process", "d": ["The chemical reactions and pathways involving L-altrarate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000006", "l": "regulation of metanephric comma-shaped body morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of metanephric comma-shaped body morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032469", "l": "endoplasmic reticulum calcium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001809", "l": "positive regulation of type IV hypersensitivity", "d": ["Any process that activates or increases the frequency, rate or extent of type IV hypersensitivity, a type of inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0055094", "l": "response to lipoprotein particle", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032961", "l": "negative regulation of inositol trisphosphate biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021975", "l": "pons reticulospinal tract morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070193", "l": "synaptonemal complex organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060372", "l": "regulation of atrial cardiac muscle cell membrane repolarization", "d": ["Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in an atrial cardiomyocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022035", "l": "rhombomere cell migration", "d": ["The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905340", "l": "regulation of protein localization to kinetochore", "d": ["Any process that modulates the frequency, rate or extent of protein localization to kinetochore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006111", "l": "regulation of gluconeogenesis", "d": ["Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048743", "l": "positive regulation of skeletal muscle fiber development", "d": ["Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900510", "l": "negative regulation of pentose catabolic process to ethanol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pentose catabolic process to ethanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061565", "l": "dAMP phosphorylation", "d": ["The process of introducing a phosphate group into dAMP, deoxyadenosine monophosphate, to produce dADP. Addition of two phosphate groups produces dATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900341", "l": "positive regulation of methane biosynthetic process from formic acid", "d": ["Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from formic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0002707", "l": "negative regulation of lymphocyte mediated immunity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060693", "l": "regulation of branching involved in salivary gland morphogenesis", "d": ["Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120162", "l": "positive regulation of cold-induced thermogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0044351", "l": "macropinocytosis", "d": ["An endocytosis process that results in the uptake of liquid material by cells from their external environment by the 'ruffling' of the cell membrane to form heterogeneously sized intracellular vesicles called macropinosomes, which can be up to 5 micrometers in size."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000382", "l": "positive regulation of mesoderm development", "d": ["Any process that activates or increases the frequency, rate or extent of mesoderm development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0018208", "l": "peptidyl-proline modification", "d": ["The modification of peptidyl-proline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044641", "l": "envenomation resulting in positive regulation of complement activation, lectin pathway in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the lectin pathway in the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035177", "l": "larval foraging behavior", "d": ["The movement of a larva through a feeding substrate whilst feeding on food."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070960", "l": "positive regulation of neutrophil mediated cytotoxicity", "d": ["Any process that increases the frequency, rate or extent of the directed killing of a target cell by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000487", "l": "maturation of 5.8S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)", "d": ["Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 8.8S rRNA, the 2S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006276", "l": "plasmid maintenance", "d": ["The maintenance of the integrity of extrachromosomal plasmid DNA; includes processes that ensure plasmids are retained in the daughter cells after cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051974", "l": "negative regulation of telomerase activity", "d": ["Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061999", "l": "regulation of cardiac endothelial to mesenchymal transition", "d": ["Any process that modulates the frequency, rate or extent of cardiac endothelial to mesenchymal transition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901627", "l": "negative regulation of postsynaptic membrane organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic membrane organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903560", "l": "3-cyano-L-alanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 3-cyano-L-alanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1905345", "l": "protein localization to cleavage furrow", "d": ["A process in which a protein is transported to, or maintained in, a location within a cleavage furrow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003409", "l": "optic cup structural organization", "d": ["The process that contributes to creating the structural organization of the optic cup. This process pertains to the physical shaping of the rudimentary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902126", "l": "(+)-pinoresinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (+)-pinoresinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062211", "l": "root regeneration", "d": ["The the regeneration process by which a damaged or lost root regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to form a new root meristem and subsequently new root."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019504", "l": "L-proline betaine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035752", "l": "lysosomal lumen pH elevation", "d": ["Any process that increases the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090188", "l": "negative regulation of pancreatic juice secretion", "d": ["Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060886", "l": "clearance of cells from fusion plate by epithelial to mesenchymal transition", "d": ["The process of epithelial to mesenchymal transition that contributes to the shaping of the semicircular canal by effectively removing epithelial cells from the fusion plate, forming the loops of the canals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0046685", "l": "response to arsenic-containing substance", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043953", "l": "protein transport by the Tat complex", "d": ["The process in which folded proteins are transported across cytoplasmic membranes of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) by the TAT complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002901", "l": "mature B cell apoptotic process", "d": ["Any apoptotic process in a B cell that is mature, having left the bone marrow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0039663", "l": "membrane fusion involved in viral entry into host cell", "d": ["Merging of the virion membrane and a host membrane (host plasma membrane or host organelle membrane) that is involved in the uptake of a virus into a host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0009164", "l": "nucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048536", "l": "spleen development", "d": ["The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.474657494018913", "identifiers": [{"i": "GO:0019058", "l": "viral life cycle", "d": ["A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0009749", "l": "response to glucose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903776", "l": "regulation of double-strand break repair via single-strand annealing, removal of nonhomologous ends", "d": ["Any process that modulates the frequency, rate or extent of double-strand break repair via single-strand annealing, removal of nonhomologous ends."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0033301", "l": "cell cycle comprising mitosis without cytokinesis", "d": ["A mitotic cell cycle in which mitosis is completed but cytokinesis does not occur, resulting in a cell containing multiple nuclei each with a chromosomal complement of the original ploidy (usually 2N)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0086072", "l": "AV node cell-bundle of His cell adhesion involved in cell communication", "d": ["The attachment of an AV node cell to an bundle of His cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032659", "l": "regulation of interleukin-16 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-16 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0016925", "l": "protein sumoylation", "d": ["The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060747", "l": "oral incubation", "d": ["A parental behavior in which fertilized eggs are taken into the mouth and held until hatching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006730", "l": "one-carbon metabolic process", "d": ["The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075225", "l": "negative regulation of sporangium germination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium germination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.503963827996756", "identifiers": [{"i": "GO:0045859", "l": "regulation of protein kinase activity", "d": ["Any process that modulates the frequency, rate or extent of protein kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:0045912", "l": "negative regulation of carbohydrate metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.604754761056498", "identifiers": [{"i": "GO:0030900", "l": "forebrain development", "d": ["The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903995", "l": "regulation of non-membrane spanning protein tyrosine kinase activity", "d": ["Any process that modulates the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006290", "l": "pyrimidine dimer repair", "d": ["The repair of UV-induced T-T, C-T and C-C dimers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900098", "l": "regulation of plasma cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of plasma cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060253", "l": "negative regulation of glial cell proliferation", "d": ["Any process that stops or decreases the rate or extent of glial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905288", "l": "vascular associated smooth muscle cell apoptotic process", "d": ["Any apoptotic process in a vascular associated smooth muscle cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045641", "l": "negative regulation of basophil differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of basophil differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010760", "l": "negative regulation of macrophage chemotaxis", "d": ["Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140231", "l": "anterograde axonal transport of neurotransmitter receptor complex", "d": ["The directed movement of a neurotransmitter receptor complex along microtubules from the cell body toward the cell periphery in nerve cell axons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019424", "l": "sulfide oxidation, using siroheme sulfite reductase", "d": ["A sulfide oxidation process that proceeds via the reaction catalyzed by siroheme sulfite reductase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021569", "l": "rhombomere 3 development", "d": ["The process whose specific outcome is the progression of rhombomere 3 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990789", "l": "thyroid gland epithelial cell proliferation", "d": ["The multiplication or reproduction of thyroid gland epithelial cells, resulting in the expansion of the thyroid gland epithelial cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0070880", "l": "fungal-type cell wall beta-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902461", "l": "negative regulation of mesenchymal stem cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0019076", "l": "viral release from host cell", "d": ["The dissemination of mature viral particles from a host cell, e.g. by cell lysis or the budding of virus particles from the cell membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042004", "l": "feminization of hermaphrodite soma", "d": ["Promotion of female sex and sexual phenotypes in the hermaphroditic soma. An example of this is found in Caenorhabditis elegans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0009265", "l": "2'-deoxyribonucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0072529", "l": "pyrimidine-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0051780", "l": "behavioral response to nutrient", "d": ["Any process that results in a change in the behavior of an organism as a result of a nutrient stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000905", "l": "sporocarp development involved in asexual reproduction", "d": ["The formation of a spore-bearing structure by fungus where spores will arise from asexual reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.934381521867174", "identifiers": [{"i": "GO:0010948", "l": "negative regulation of cell cycle process", "d": ["Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0099607", "l": "lateral attachment of mitotic spindle microtubules to kinetochore", "d": ["The cell cycle process in which sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. Attachment precedes migration along microtubules towards the spindle equator (metaphase plate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140495", "l": "migracytosis", "d": ["A cell migration-dependent mechanism for releasing cellular contents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097340", "l": "inhibition of cysteine-type endopeptidase activity", "d": ["Any process that prevents the activation of an inactive cysteine-type endopeptidase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0010863", "l": "positive regulation of phospholipase C activity", "d": ["Any process that increases the rate of phospholipase C activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046300", "l": "2,4-dichlorophenoxyacetic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140325", "l": "negative regulation of protein localization to medial cortex", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the medial cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0045631", "l": "regulation of mechanoreceptor differentiation", "d": ["Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0099542", "l": "trans-synaptic signaling by endocannabinoid", "d": ["Cell-cell signaling in either direction across the synaptic cleft, mediated by an endocannabinoid ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0002279", "l": "mast cell activation involved in immune response", "d": ["The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048055", "l": "R2/R5 development", "d": ["The process whose specific outcome is the progression of the R2 and R5 pair of photoreceptors in the eye over time, from their formation to the mature structures. R2 and R5 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0002293", "l": "alpha-beta T cell differentiation involved in immune response", "d": ["The process in which an antigenically naive alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009910", "l": "negative regulation of flower development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of flower development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021694", "l": "cerebellar Purkinje cell layer formation", "d": ["The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.081967935480229", "identifiers": [{"i": "GO:0003014", "l": "renal system process", "d": ["A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075045", "l": "regulation of formation by symbiont of haustorium for nutrient acquisition from host", "d": ["Any process that modulates the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030860", "l": "regulation of polarized epithelial cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of polarized epithelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904820", "l": "peritoneum development", "d": ["The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0042455", "l": "ribonucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035160", "l": "maintenance of epithelial integrity, open tracheal system", "d": ["Ensuring that tracheal tubes in an open tracheal system maintain their epithelial structure during the cell shape changes and movements that occur during the branching process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018168", "l": "protein-phycoerythrobilin linkage via S-phycoerythrobilin-L-cysteine", "d": ["The linkage of the chromophore phycoerythrobilin to phycoerythrocyanin via S-phycoerythrobilin-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009939", "l": "positive regulation of gibberellic acid mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of gibberellic acid mediated signaling activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014915", "l": "regulation of muscle filament sliding speed involved in regulation of the velocity of shortening in skeletal muscle contraction", "d": ["Any process that modulates the velocity of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106381", "l": "purine deoxyribonucleotide salvage", "d": ["Any process which produces a purine deoxyribonucleotide from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0072010", "l": "glomerular epithelium development", "d": ["The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090464", "l": "intracellular histidine homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of histidine within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048533", "l": "sporocyte differentiation", "d": ["The process in which a relatively unspecialized floral cell acquires the specialized features of a sporocyte. Sporocytes are the haploid spores of angiosperms. Once formed, they undergo meiotic divisions to form microspores and megaspores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003317", "l": "cardioblast cell midline fusion", "d": ["The attachment of cardiac progenitor cells to one another that contributes to the formation of the heart rudiment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0039707", "l": "pore formation by virus in membrane of host cell", "d": ["The aggregation, arrangement and bonding together of a set of components by a virus to form a pore complex in a membrane of a host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904127", "l": "regulation of convergent extension involved in somitogenesis", "d": ["Any process that modulates the frequency, rate or extent of convergent extension involved in somitogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1904305", "l": "negative regulation of gastro-intestinal system smooth muscle contraction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010159", "l": "specification of animal organ position", "d": ["The regionalization process in which information that determines the correct position at which animal organ primordia are formed is generated and perceived resulting in correct positioning of the new animal organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903591", "l": "negative regulation of lysozyme activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lysozyme activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900517", "l": "positive regulation of xylose catabolic process to ethanol", "d": ["Any process that activates or increases the frequency, rate or extent of xylose catabolic process to ethanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001770", "l": "establishment of natural killer cell polarity", "d": ["The directed orientation of natural killer cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with a cell displaying natural killer cell activating ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045710", "l": "negative regulation of larval salivary gland boundary specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in a larval organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0019081", "l": "viral translation", "d": ["A process by which viral mRNA is translated into viral protein, using the host cellular machinery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045490", "l": "pectin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019616", "l": "catechol catabolic process, meta-cleavage", "d": ["The chemical reactions and pathways resulting in the breakdown of catechol via the meta-cleavage pathway, in which the catechol aromatic ring is broken between a hydroxylated carbon atom and an adjacent unsubstituted carbon atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0003146", "l": "heart jogging", "d": ["The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048535", "l": "lymph node development", "d": ["The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1902284", "l": "neuron projection extension involved in neuron projection guidance", "d": ["Any neuron projection extension that is involved in neuron projection guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032112", "l": "negative regulation of protein histidine kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of protein histidine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043041", "l": "amino acid activation for nonribosomal peptide biosynthetic process", "d": ["Activation of an amino acid for incorporation into a peptide by a nonribosomal process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905542", "l": "negative regulation of L-arginine import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-arginine import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141011", "l": "siRNA-mediated retrotransposon silencing by mRNA destabilization", "d": ["A retrotransposon silencing mechanism in which mRNAs transcribed from transposons are targeted for degradation by a siRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904358", "l": "positive regulation of telomere maintenance via telomere lengthening", "d": ["Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905867", "l": "epididymis development", "d": ["The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035942", "l": "dehydroepiandrosterone secretion", "d": ["The regulated release of dehydroepiandrosterone (3beta-hydroxyandrost-5-en-17-one) into the circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0008272", "l": "sulfate transport", "d": ["The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033509", "l": "glutamate catabolic process to propionate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including propionate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031288", "l": "sorocarp morphogenesis", "d": ["The process in which the sorocarp is generated and organized. An example of this process is found in Dictyostelium discoideum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032919", "l": "spermine acetylation", "d": ["The modification of spermine by addition of acetyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035359", "l": "negative regulation of peroxisome proliferator activated receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903514", "l": "release of sequestered calcium ion into cytosol by endoplasmic reticulum", "d": ["The directed movement of calcium ion from endoplasmic reticulum to cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903604", "l": "cytochrome metabolic process", "d": ["The chemical reactions and pathways involving a cytochrome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045869", "l": "negative regulation of single stranded viral RNA replication via double stranded DNA intermediate", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046799", "l": "recruitment of helicase-primase complex to DNA lesions", "d": ["The recruitment of the helicase-primase complex to viral DNA lesions during viral DNA repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0035113", "l": "embryonic appendage morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0000305", "l": "response to oxygen radical", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0015821", "l": "methionine transport", "d": ["The directed movement of methionine, 2-amino-4-(methylthio)butanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035623", "l": "renal glucose absorption", "d": ["A renal system process in which glucose is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903934", "l": "positive regulation of DNA primase activity", "d": ["Any process that activates or increases the frequency, rate or extent of DNA primase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0016240", "l": "autophagosome membrane docking", "d": ["The initial attachment of an autophagosome membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901803", "l": "1,5-anhydro-D-fructose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 1,5-anhydro-D-fructose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050899", "l": "nitrile catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090166", "l": "Golgi disassembly", "d": ["A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0019287", "l": "isopentenyl diphosphate biosynthetic process, mevalonate pathway", "d": ["The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044597", "l": "daunorubicin metabolic process", "d": ["The chemical reactions and pathways involving daunorubicin, a chemotherapeutic of the anthracycline family that is given as a treatment for some types of cancer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900712", "l": "positive regulation of tensidol B biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of tensidol B biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015786", "l": "UDP-glucose transmembrane transport", "d": ["The process in which UDP-glucose is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071765", "l": "nuclear inner membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006408", "l": "snRNA export from nucleus", "d": ["The directed movement of snRNA from the nucleus to the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0051299", "l": "centrosome separation", "d": ["The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001159", "l": "regulation of protein localization by the Cvt pathway", "d": ["Any process that modulates the frequency, rate or extent of protein localization by the Cvt pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003198", "l": "epithelial to mesenchymal transition involved in endocardial cushion formation", "d": ["A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090426", "l": "actin filament bundle convergence", "d": ["A process of actin filament bundle distribution that results in the compaction of actin filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905255", "l": "regulation of RNA binding transcription factor activity", "d": ["Any process that modulates the frequency, rate or extent of RNA binding transcription factor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0033275", "l": "actin-myosin filament sliding", "d": ["The sliding movement of actin thin filaments and myosin thick filaments past each other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0007020", "l": "microtubule nucleation", "d": ["The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0020013", "l": "modulation by symbiont of host erythrocyte aggregation", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of erythrocyte aggregation in its host organism, e.g. the binding of parasite-infected erythrocytes to uninfected erythrocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903867", "l": "extraembryonic membrane development", "d": ["The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0006623", "l": "protein targeting to vacuole", "d": ["The process of directing proteins towards the vacuole, usually using signals contained within the protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048505", "l": "regulation of timing of cell differentiation", "d": ["The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1990956", "l": "fibroblast chemotaxis", "d": ["The directed movement of a fibroblast guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:2001014", "l": "regulation of skeletal muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901873", "l": "regulation of post-translational protein modification", "d": ["Any process that modulates the frequency, rate or extent of post-translational protein modification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.003741351937961", "identifiers": [{"i": "GO:0021885", "l": "forebrain cell migration", "d": ["The orderly movement of a cell from one site to another at least one of which is located in the forebrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904988", "l": "negative regulation of endothelial cell activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071838", "l": "cell proliferation in bone marrow", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population in the bone marrow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0022410", "l": "circadian sleep/wake cycle process", "d": ["A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901997", "l": "negative regulation of indoleacetic acid biosynthetic process via tryptophan", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900838", "l": "negative regulation of fumigaclavine C biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fumigaclavine C biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010713", "l": "negative regulation of collagen metabolic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904762", "l": "positive regulation of myofibroblast differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of myofibroblast differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0010719", "l": "negative regulation of epithelial to mesenchymal transition", "d": ["Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000654", "l": "regulation of cellular response to testosterone stimulus", "d": ["Any process that modulates the frequency, rate or extent of cellular response to testosterone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0060021", "l": "roof of mouth development", "d": ["The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:2000896", "l": "amylopectin metabolic process", "d": ["The chemical reactions and pathways involving an amylopectin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.94117494528583", "identifiers": [{"i": "GO:0015695", "l": "organic cation transport", "d": ["The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072597", "l": "maintenance of protein location in chloroplast", "d": ["Any process in which a protein is maintained in a specific location in a chloroplast, and is prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902656", "l": "calcium ion import into cytosol", "d": ["The directed movement of calcium ion into a cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904448", "l": "regulation of aspartate secretion", "d": ["Any process that modulates the frequency, rate or extent of aspartate secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060654", "l": "mammary gland cord elongation", "d": ["The process in which the mammary gland sprout grows along its axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0022011", "l": "myelination in peripheral nervous system", "d": ["The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048360", "l": "root cap mucilage metabolic process", "d": ["The chemical reactions and pathways involving mucilage that occur in the root cap; mucilage is normally synthesized during root growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900672", "l": "positive regulation of F-9775A biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of F-9775A biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903339", "l": "negative regulation of cell wall organization or biogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell wall organization or biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006313", "l": "DNA transposition", "d": ["A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048847", "l": "adenohypophysis formation", "d": ["The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0051176", "l": "positive regulation of sulfur metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006238", "l": "CMP salvage", "d": ["Any process that generates CMP, cytidine monophosphate, from derivatives of it without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0009162", "l": "deoxyribonucleoside monophosphate metabolic process", "d": ["The chemical reactions and pathways involving a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062235", "l": "axonemal basal plate assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an axonemal basal plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070782", "l": "phosphatidylserine exposure on apoptotic cell surface", "d": ["A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043151", "l": "DNA synthesis involved in double-strand break repair via single-strand annealing", "d": ["The synthesis of DNA that contributes to the process of double-strand break repair via single-strand annealing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007258", "l": "JUN phosphorylation", "d": ["The process of introducing a phosphate group into a JUN protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035095", "l": "behavioral response to nicotine", "d": ["Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070445", "l": "regulation of oligodendrocyte progenitor proliferation", "d": ["Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902869", "l": "regulation of amacrine cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of amacrine cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902823", "l": "negative regulation of late endosome to lysosome transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of late endosome to lysosome transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903253", "l": "hercynylcysteine sulfoxide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hercynylcysteine sulfoxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0001703", "l": "gastrulation with mouth forming first", "d": ["A gastrulation process in which the initial invagination becomes the mouth and the anus forms second."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000623", "l": "negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009423", "l": "chorismate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075267", "l": "aecium development", "d": ["The process in which a cup-like structure containing chains of aeciospores is formed. This is characteristic of the rust fungus and typically, the first dikaryotic spores (aeciospores) are produced in the aecium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040026", "l": "positive regulation of vulval development", "d": ["Any process that activates or increases the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140755", "l": "reorganization of host cellular membranes to establish sites of replication", "d": ["A process in which a virus triggers host intracellular membranes to be reorganized, forming membranous webs, which are thought to be the site of replication or certain viruses, for example the HPV virus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1905314", "l": "semi-lunar valve development", "d": ["The process whose specific outcome is the progression of a semi-lunar valve over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.723674083902068", "identifiers": [{"i": "GO:0006520", "l": "amino acid metabolic process", "d": ["The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060988", "l": "lipid tube assembly", "d": ["The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as they fuse or undergo fission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061471", "l": "karyomere assembly", "d": ["The process where the nuclear membrane engulfs condensed chromosomes to form karyomeres during M phase of the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0048194", "l": "Golgi vesicle budding", "d": ["The evagination of the Golgi membrane, resulting in formation of a vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0002834", "l": "regulation of response to tumor cell", "d": ["Any process that modulates the frequency, rate, or extent of a response to tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120069", "l": "positive regulation of stomach fundus smooth muscle contraction", "d": ["Any process that increases the frequency, rate or extent of any stomach fundus smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009682", "l": "induced systemic resistance", "d": ["A response to non-pathogenic bacteria that confers broad spectrum systemic resistance to disease that does not depend upon salicylic acid signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009210", "l": "pyrimidine ribonucleoside triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904243", "l": "negative regulation of pancreatic trypsinogen secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic trypsinogen secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000592", "l": "regulation of metanephric DCT cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of metanephric DCT cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0016226", "l": "iron-sulfur cluster assembly", "d": ["The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015679", "l": "plasma membrane copper ion transport", "d": ["The directed movement of copper ions across the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002545", "l": "chronic inflammatory response to non-antigenic stimulus", "d": ["A chronic inflammatory response to a non-antigenic stimulus such as heat or physical trauma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903021", "l": "regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands", "d": ["Any process that modulates the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0090307", "l": "mitotic spindle assembly", "d": ["Mitotic bipolar spindle assembly begins with spindle microtubule nucleation from the separated spindle pole body, includes spindle elongation during prometaphase, and is complete when all kinetochores are stably attached the spindle, and the spindle assembly checkpoint is satisfied."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019335", "l": "3-methylquinoline catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0001774", "l": "microglial cell activation", "d": ["The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0043447", "l": "alkane biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070808", "l": "regulation of Hulle cell development", "d": ["Any process that modulates the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "44.940053744082149", "identifiers": [{"i": "GO:0030154", "l": "cell differentiation", "d": ["The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120154", "l": "negative regulation of ERBB4 signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ERBB4 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0052646", "l": "alditol phosphate metabolic process", "d": ["The chemical reactions and pathways involving alditol phosphates, any phosphorylated polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905782", "l": "positive regulation of phosphatidylserine exposure on apoptotic cell surface", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010433", "l": "bract morphogenesis", "d": ["The process in which the anatomical structure of a bract are generated and organized. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904795", "l": "positive regulation of euchromatin binding", "d": ["Any process that activates or increases the frequency, rate or extent of euchromatin binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006437", "l": "tyrosyl-tRNA aminoacylation", "d": ["The process of coupling tyrosine to tyrosyl-tRNA, catalyzed by tyrosyl-tRNA synthetase. The tyrosyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tyrosine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000289", "l": "regulation of photoreceptor cell axon guidance", "d": ["Any process that modulates the frequency, rate or extent of photoreceptor cell axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0061439", "l": "kidney vasculature morphogenesis", "d": ["The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045736", "l": "negative regulation of cyclin-dependent protein serine/threonine kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904558", "l": "response to dextromethorphan", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1905209", "l": "positive regulation of cardiocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060344", "l": "liver trabecula formation", "d": ["The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0034080", "l": "CENP-A containing chromatin assembly", "d": ["The formation of chromatin containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070150", "l": "mitochondrial glycyl-tRNA aminoacylation", "d": ["The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900601", "l": "endocrocin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of endocrocin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002363", "l": "alpha-beta T cell lineage commitment", "d": ["The process in which a pro-T cell becomes committed to becoming an alpha-beta T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002664", "l": "regulation of T cell tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of T cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0051568", "l": "histone H3-K4 methylation", "d": ["The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032820", "l": "regulation of natural killer cell proliferation involved in immune response", "d": ["Any process that modulates the frequency, rate or extent of natural killer cell proliferation as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0044154", "l": "histone H3-K14 acetylation", "d": ["The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 14 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007321", "l": "sperm displacement", "d": ["The physical displacement of sperm stored from previous mating encounters."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902893", "l": "regulation of miRNA transcription", "d": ["Any process that modulates the frequency, rate or extent of microRNA (miRNA) gene transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030862", "l": "positive regulation of polarized epithelial cell differentiation", "d": ["Any process that activates or increases the rate or extent of polarized epithelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.566286445527851", "identifiers": [{"i": "GO:0002822", "l": "regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "d": ["Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900781", "l": "fumiquinazoline C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the indole alkaloid fumiquinazoline C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990569", "l": "UDP-N-acetylglucosamine transmembrane transport", "d": ["The process in which UDP-N-acetylglucosamine is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034351", "l": "negative regulation of glial cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002104", "l": "endonucleolytic cleaveage between 4.5S rRNA and 5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)", "d": ["Endonucleolytic cleavage between the 5S rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001087", "l": "sophorose transport", "d": ["The directed movement of a sophoroseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015689", "l": "molybdate ion transport", "d": ["The directed movement of molybdate (MoO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Molybdate is the bivalent anion derived from molybdic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061361", "l": "positive regulation of maintenance of bipolar cell polarity regulating cell shape", "d": ["Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000034", "l": "regulation of seed maturation", "d": ["Any process that modulates the frequency, rate or extent of seed maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904391", "l": "response to ciliary neurotrophic factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0002792", "l": "negative regulation of peptide secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021570", "l": "rhombomere 4 development", "d": ["The process whose specific outcome is the progression of rhombomere 4 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035480", "l": "regulation of Notch signaling pathway involved in heart induction", "d": ["Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0021877", "l": "forebrain neuron fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron that resides in the forebrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902748", "l": "positive regulation of lens fiber cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of lens fiber cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903682", "l": "negative regulation of epithelial cell-cell adhesion involved in epithelium migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903843", "l": "cellular response to arsenite ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000118", "l": "regulation of sodium-dependent phosphate transport", "d": ["Any process that modulates the frequency, rate or extent of sodium-dependent phosphate transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.232064878529073", "identifiers": [{"i": "GO:0061538", "l": "histamine secretion, neurotransmission", "d": ["The controlled release of histamine by a cell, in which the histamine acts as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010596", "l": "negative regulation of endothelial cell migration", "d": ["Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046723", "l": "malic acid secretion", "d": ["The controlled release of malic acid, hydroxybutanedioic (hydroxysuccinic) acid, by a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010912", "l": "positive regulation of isomerase activity", "d": ["Any process that increases the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904998", "l": "negative regulation of leukocyte adhesion to arterial endothelial cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044066", "l": "modification by symbiont of host cell nucleus", "d": ["The process in which a symbiont organism effects a change in the structure or function of its host cell nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001040", "l": "positive regulation of cellular response to drug", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to drug."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000905", "l": "negative regulation of starch metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of starch metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051518", "l": "positive regulation of bipolar cell growth", "d": ["Any process that activates or increases the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "28.124667579006747", "identifiers": [{"i": "GO:0032502", "l": "developmental process", "d": ["A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019930", "l": "cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester biosynthetic process from peptidyl-aspartic acid", "d": ["The modification of peptidyl-aspartic acid to form peptidyl-cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid aspartate ester, typical of the barley lipid transfer protein 1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0090594", "l": "inflammatory response to wounding", "d": ["The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904152", "l": "regulation of retrograde protein transport, ER to cytosol", "d": ["Any process that modulates the frequency, rate or extent of retrograde protein transport, ER to cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106427", "l": "negative regulation of kainate selective glutamate receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002751", "l": "antigen processing and presentation following receptor mediated endocytosis", "d": ["Antigen processing and presentation which is initiated by uptake of antigen receptor-mediated endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036036", "l": "cardiac neural crest cell delamination", "d": ["The negative regulation of cell adhesion process in which a cardiac neural crest cell physically separates from the rest of the neural tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010269", "l": "response to selenium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019599", "l": "(R)-4-hydroxymandelate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (R)-4-hydroxymandelate, the anion of (R)-4-hydroxymandelic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904414", "l": "positive regulation of cardiac ventricle development", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac ventricle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090668", "l": "endothelial cell chemotaxis to vascular endothelial growth factor", "d": ["The directed movement of an endothelial cell in response to the presence of vascular endothelial growth factor (VEGF)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002211", "l": "behavioral defense response to insect", "d": ["A behavioral response seeking to protect an organism from an a perceived external threat from an insect or insects to that organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061382", "l": "Malpighian tubule tip cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070634", "l": "transepithelial ammonium transport", "d": ["The directed movement of ammonium ions from one side of an epithelium to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002612", "l": "positive regulation of plasmacytoid dendritic cell antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031665", "l": "negative regulation of lipopolysaccharide-mediated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140647", "l": "P450-containing electron transport chain", "d": ["A electron transport chain in which one or more electron carriers operate to transfer electrons from donors to a cytochrome P450 protein or domain. Electron carriers operating in this chain include FAD-containing flavoproteins or domains, FMN domains, ferredoxins and cytochrome b5. The reduced cytochrome P450 functions as the terminal oxidase and participates in a wide range of biochemical pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0080033", "l": "response to nitrite", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035582", "l": "sequestering of BMP in extracellular matrix", "d": ["Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035298", "l": "regulation of Malpighian tubule size", "d": ["Ensuring that a Malpighian tubule is the correct length and diameter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000964", "l": "negative regulation of cellooligosaccharide catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904494", "l": "regulation of substance P secretion, neurotransmission", "d": ["Any process that modulates the frequency, rate or extent of substance P secretion, neurotransmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014861", "l": "regulation of skeletal muscle contraction via regulation of action potential", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0051665", "l": "membrane raft localization", "d": ["Any process in which membrane rafts are transported to, or maintained in, a specific location. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0042465", "l": "kinesis", "d": ["The movement of a cell or organism in response to a stimulus in which the rate of movement depends on the intensity (rather than the direction) of the stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0044737", "l": "modulation of acid-sensing ion channel in another organism", "d": ["Any process in which an organism effects a change in the frequency, rate or extent of the activity of an acid-sensing ion channel (ASIC) in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0098935", "l": "dendritic transport", "d": ["The directed movement of organelles or molecules along microtubules in dendrites."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0030656", "l": "regulation of vitamin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046549", "l": "retinal cone cell development", "d": ["Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051572", "l": "negative regulation of histone H3-K4 methylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006161", "l": "deoxyguanosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0039692", "l": "single stranded viral RNA replication via double stranded DNA intermediate", "d": ["A viral genome replication where the template is single-stranded RNA (ssRNA), and which proceeds via a double stranded DNA (dsDNA) intermediate molecule. Viral genomic RNA is first reverse transcribed into dsDNA, which integrates into the host chromosomal DNA, where it is transcribed by host RNA polymerase II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061137", "l": "bud dilation", "d": ["The process in which a branch bud increases radially. A branch bud is the initial area of outgrowth in the formation of a new branch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075192", "l": "haustorium mother cell formation", "d": ["The process in which a symbiont cell is formed, separated from the tip of an infection hypha by a septum. The haustorium mother cell usually contains 2-4 fungal nuclei, and its function is to attach and penetrate the host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072264", "l": "metanephric glomerular endothelium development", "d": ["The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000611", "l": "positive regulation of thyroid hormone generation", "d": ["Any process that activates or increases the frequency, rate or extent of thyroid hormone generation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0060914", "l": "heart formation", "d": ["The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.881813014728969", "identifiers": [{"i": "GO:0051248", "l": "negative regulation of protein metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006990", "l": "positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response", "d": ["The activation of genes whose promoters contain a specific sequence elements such as the unfolded protein response element (UPRE; consensus CAGCGTG) or the ER stress-response element (ERSE; CCAAN(N)9CCACG), as a result of signaling via the unfolded protein response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019065", "l": "receptor-mediated endocytosis of virus by host cell", "d": ["Any receptor-mediated endocytosis that is involved in the uptake of a virus into a host cell; successive instances of virus endocytosis result in the accumulation of virus particles within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046115", "l": "guanosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of guanine, guanine riboside, a nucleoside with a wide species distribution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075187", "l": "hyphopodium formation", "d": ["The process in which a specialized structure, consisted of stalked, thick-walled, lobed cells of vegetative epiphytic hyphae, is formed, to attach and penetrate the host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0043371", "l": "negative regulation of CD4-positive, alpha-beta T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010924", "l": "regulation of inositol-polyphosphate 5-phosphatase activity", "d": ["Any process that modulates the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006561", "l": "proline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090720", "l": "primary adaptive immune response", "d": ["An adaptive immune response against an antigen not previously encountered by immune system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060346", "l": "bone trabecula formation", "d": ["The process of creating a trabecula in the bone. A trabecula is a tissue element in the form of a small beam, strut or rod."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032704", "l": "negative regulation of interleukin-20 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-20 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051558", "l": "phlobaphene metabolic process", "d": ["The chemical reactions and pathways involving phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010867", "l": "positive regulation of triglyceride biosynthetic process", "d": ["Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0001752", "l": "compound eye photoreceptor fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a compound eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000766", "l": "negative regulation of cytoplasmic translation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070706", "l": "RNA nucleotide deletion", "d": ["The modification of an RNA molecule by removal of a single nucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0048465", "l": "corolla development", "d": ["The process whose specific outcome is the progression of the corolla over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006148", "l": "inosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015794", "l": "glycerol-3-phosphate transmembrane transport", "d": ["The process in which glycerol-3-phosphate is transported across a membrane. Glycerol-3-phosphate is a phosphoric monoester of glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019082", "l": "viral protein processing", "d": ["Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a viral protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017189", "l": "N-terminal peptidyl-alanine acetylation", "d": ["The acetylation of the N-terminal alanine of proteins; catalyzed by peptide alpha-N-acetyltransferase or other enzymes of this class, such as ribosomal-protein-alanine N-acetyltransferase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905817", "l": "positive regulation of dorsal/ventral axon guidance", "d": ["Any process that activates or increases the frequency, rate or extent of dorsal/ventral axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000491", "l": "positive regulation of hepatic stellate cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900812", "l": "helvolic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of helvolic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043182", "l": "vacuolar sequestering of sodium ion", "d": ["The process of transporting sodium ions into, and confining within, a vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030861", "l": "negative regulation of polarized epithelial cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of polarized epithelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0070266", "l": "necroptotic process", "d": ["A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098696", "l": "regulation of neurotransmitter receptor localization to postsynaptic specialization membrane", "d": ["Any process that modulates the frequency, rate or extent of neurotransmitter receptor localization to postsynaptic specialization membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009829", "l": "cell wall modification involved in fruit ripening", "d": ["The series of events resulting in chemical or structural alterations of existing cell walls that contribute to fruit ripening."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:2000278", "l": "regulation of DNA biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of DNA biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0032091", "l": "negative regulation of protein binding", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017183", "l": "peptidyl-diphthamide biosynthetic process from peptidyl-histidine", "d": ["The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003184", "l": "pulmonary valve morphogenesis", "d": ["The process in which the structure of the pulmonary valve is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905564", "l": "positive regulation of vascular endothelial cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0097018", "l": "renal albumin absorption", "d": ["A renal system process in which albumin is taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903637", "l": "negative regulation of protein insertion into mitochondrial outer membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein insertion into mitochondrial outer membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905154", "l": "negative regulation of membrane invagination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0050856", "l": "regulation of T cell receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0035882", "l": "defecation rhythm", "d": ["The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043397", "l": "regulation of corticotropin-releasing hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990734", "l": "astral microtubule anchoring at mitotic spindle pole body", "d": ["Any process in which an astral microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902056", "l": "(25S)-Delta(7)-dafachronate metabolic process", "d": ["The chemical reactions and pathways involving (25S)-Delta(7)-dafachronate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042996", "l": "regulation of Golgi to plasma membrane protein transport", "d": ["Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019741", "l": "pentacyclic triterpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035007", "l": "regulation of melanization defense response", "d": ["Any process that affects the rate, extent or location of the melanization defense response during injury or invasion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902290", "l": "positive regulation of defense response to oomycetes", "d": ["Any process that activates or increases the frequency, rate or extent of defense response to oomycetes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0040020", "l": "regulation of meiotic nuclear division", "d": ["Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.27567501185726", "identifiers": [{"i": "GO:0017145", "l": "stem cell division", "d": ["The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901450", "l": "positive regulation of response to butan-1-ol", "d": ["Any process that activates or increases the frequency, rate or extent of response to butan-1-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0022400", "l": "regulation of rhodopsin mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045724", "l": "positive regulation of cilium assembly", "d": ["Any process that activates or increases the frequency, rate or extent of the formation of a cilium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090256", "l": "regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis", "d": ["Any process that modulates the frequency, rate, or extent of the multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000960", "l": "regulation of cellooligosaccharide metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellooligosaccharide metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.980302069293842", "identifiers": [{"i": "GO:0010927", "l": "cellular component assembly involved in morphogenesis", "d": ["The cellular component assembly that is part of the initial shaping of the component during its developmental progression."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097701", "l": "response to pulsatile fluid shear stress", "d": ["Any response to fluid shear stress where the fluid is flowing across a solid surface with periodic variations. For example, the endothelium in straight parts of the artery tree is subjected to pulsatile shear stress with a significant forward direction, which is believed to be an important physiological stimulus enhancing vessel compliance and conferring anti-thrombotic, anti-adhesive, and anti-inflammatory effects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900648", "l": "positive regulation of chanoclavine-I aldehyde biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044129", "l": "positive regulation of development of symbiont in host", "d": ["Any process in which the symbiont activates or maintains its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1905666", "l": "regulation of protein localization to endosome", "d": ["Any process that modulates the frequency, rate or extent of protein localization to endosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072703", "l": "cellular response to methyl methanesulfonate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901731", "l": "positive regulation of platelet aggregation", "d": ["Any process that activates or increases the frequency, rate or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075313", "l": "basidium development", "d": ["The process that leads to the development of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052183", "l": "perturbation of symbiont cellular component", "d": ["The process in which a host organism destabilizes a cellular component of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0051546", "l": "keratinocyte migration", "d": ["The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038014", "l": "negative regulation of insulin receptor signaling pathway by insulin receptor internalization", "d": ["Any process in which internalization of an insulin receptor stops, prevents, or reduces the frequency, rate or extent of insulin receptor signal transduction. Internalization of insulin in association with its receptor clears insulin from the circulation and is necessary for subsequent insulin dissociation from the receptor and insulin degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900562", "l": "dehydroaustinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dehydroaustinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904441", "l": "regulation of thyroid gland epithelial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of thyroid gland epithelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018171", "l": "peptidyl-cysteine oxidation", "d": ["The oxidation of peptidyl-cysteine to peptidyl-L-cysteine sulfinic acid or peptidyl-L-cysteine sulfenic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030011", "l": "maintenance of cell polarity", "d": ["The maintenance of established anisotropic intracellular organization or cell growth patterns."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904300", "l": "positive regulation of transcytosis", "d": ["Any process that activates or increases the frequency, rate or extent of transcytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106297", "l": "E-series resolvin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of resolvin family E-series, hydroxy fatty acids derived from icosapentaenoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003240", "l": "conus arteriosus formation", "d": ["The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003153", "l": "closure of embryonic heart tube", "d": ["Creation of the central hole of the embryonic heart tube by sealing the edges of an epithelial fold."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0099533", "l": "positive regulation of presynaptic cytosolic calcium concentration", "d": ["Any process that increases the concentration of calcium ions in the presynaptic cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903661", "l": "positive regulation of complement-dependent cytotoxicity", "d": ["Any process that activates or increases the frequency, rate or extent of complement-dependent cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.967140482697559", "identifiers": [{"i": "GO:0045143", "l": "homologous chromosome segregation", "d": ["The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035837", "l": "ergot alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an ergot alkaloid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070614", "l": "tungstate ion transport", "d": ["The directed movement of tungstate (WO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tungstate is a bivalent oxoanion of tungsten."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0015761", "l": "mannose transmembrane transport", "d": ["The process in which mannose is transported across a lipid bilayer, from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120072", "l": "positive regulation of pyloric antrum smooth muscle contraction", "d": ["Any process that increases the frequency, rate or extent of any pyloric antrum smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075220", "l": "positive regulation of zoospore encystment on host", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044011", "l": "single-species biofilm formation on inanimate substrate", "d": ["A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901710", "l": "regulation of homoserine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of homoserine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042420", "l": "dopamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0015912", "l": "short-chain fatty acid transport", "d": ["The directed movement of short-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A short-chain fatty acid is a fatty acid with an aliphatic tail of less than 6 carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006853", "l": "carnitine shuttle", "d": ["The transfer of acyl groups to and from acyl-CoA molecules to form O-acylcarnitine, which can exchange across the mitochondrial inner membrane with unacylated carnitine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006634", "l": "hexadecanal biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hexadecanal, the C16 straight chain aldehyde."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032110", "l": "regulation of protein histidine kinase activity", "d": ["Any process that modulates the frequency, rate or extent of protein histidine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.248384282929521", "identifiers": [{"i": "GO:0002573", "l": "myeloid leukocyte differentiation", "d": ["The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900155", "l": "negative regulation of bone trabecula formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bone trabecula formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0018293", "l": "protein-FAD linkage", "d": ["The formation of a linkage between a protein amino acid and flavin-adenine dinucleotide (FAD)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014708", "l": "regulation of somitomeric trunk muscle development", "d": ["Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045925", "l": "positive regulation of female receptivity", "d": ["Any process that activates or increases the receptiveness of a female to male advances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.879406879579491", "identifiers": [{"i": "GO:0001843", "l": "neural tube closure", "d": ["The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014709", "l": "positive regulation of somitomeric trunk muscle development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015722", "l": "canalicular bile acid transport", "d": ["Enables the transfer of bile acid from one side of a hepatocyte plasma membrane into a bile canaliculus. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030322", "l": "stabilization of membrane potential", "d": ["The accomplishment of a non-fluctuating membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160020", "l": "positive regulation of ferroptosis", "d": ["Any process that activates or increases the frequency, rate or extent of ferroptosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0009313", "l": "oligosaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0009312", "l": "oligosaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900913", "l": "positive regulation of olefin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of olefin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903593", "l": "regulation of histamine secretion by mast cell", "d": ["Any process that modulates the frequency, rate or extent of histamine secretion by mast cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.235616146829116", "identifiers": [{"i": "GO:0002438", "l": "acute inflammatory response to antigenic stimulus", "d": ["An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090320", "l": "regulation of chylomicron remnant clearance", "d": ["Any process that modulates the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010880", "l": "regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum", "d": ["Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901914", "l": "negative regulation of capsule organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of capsule organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000942", "l": "regulation of amylopectin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of amylopectin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905339", "l": "positive regulation of cohesin unloading", "d": ["Any process that activates or increases the frequency, rate or extent of cohesin unloading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006449", "l": "regulation of translational termination", "d": ["Any process that modulates the frequency, rate or extent of translational termination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042858", "l": "chrysobactin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000069", "l": "regulation of post-embryonic root development", "d": ["Any process that modulates the frequency, rate or extent of post-embryonic root development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120158", "l": "positive regulation of collagen catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035654", "l": "clathrin-coated vesicle cargo loading, AP-3-mediated", "d": ["Formation of a macromolecular complex between proteins of the AP-3 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. In some cases, the AP-3 complex is a heterotetrameric AP-type membrane coat adaptor complex that, in some organisms, links clathrin to the membrane surface of a vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072267", "l": "metanephric capsule specification", "d": ["The regionalization process in which the identity of the metanephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009728", "l": "detection of gibberellic acid stimulus", "d": ["The series of events in which a gibberellic acid stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902662", "l": "regulation of peptidyl-L-cysteine S-palmitoylation", "d": ["Any process that modulates the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905591", "l": "regulation of optical nerve axon regeneration", "d": ["Any process that modulates the frequency, rate or extent of optical nerve axon regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0048443", "l": "stamen development", "d": ["The process whose specific outcome is the progression of the stamen over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.313152904011119", "identifiers": [{"i": "GO:0010646", "l": "regulation of cell communication", "d": ["Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905531", "l": "positive regulation of uracil import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of uracil import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000301", "l": "retrograde transport, vesicle recycling within Golgi", "d": ["The retrograde movement of substances within the Golgi, mediated by COP I vesicles. Cis-Golgi vesicles are constantly moving forward through the Golgi stack by cisternal progression, eventually becoming trans-Golgi vesicles. They then selectively transport membrane and luminal proteins from the trans- to the medial-Golgi while leaving others behind in the trans-Golgi cisternae; similarly, they selectively move proteins from the medial- to the cis-Golgi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900177", "l": "regulation of aflatoxin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of aflatoxin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090727", "l": "positive regulation of brood size", "d": ["Any process that increases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002893", "l": "negative regulation of type II hypersensitivity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1900555", "l": "emericellamide metabolic process", "d": ["The chemical reactions and pathways involving emericellamide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900294", "l": "regulation of heptasaccharide transport", "d": ["Any process that modulates the frequency, rate or extent of heptasaccharide transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003332", "l": "negative regulation of extracellular matrix constituent secretion", "d": ["Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900845", "l": "positive regulation of monodictyphenone biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of monodictyphenone biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035807", "l": "positive regulation of blood coagulation in another organism", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071663", "l": "positive regulation of granzyme B production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of granzyme B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990255", "l": "subsynaptic reticulum organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a subsynaptic reticulum. A subsynaptic reticulum is an elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001109", "l": "regulation of lens epithelial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of lens epithelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0071422", "l": "succinate transmembrane transport", "d": ["The process in which succinate is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046648", "l": "positive regulation of gamma-delta T cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of gamma-delta T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071658", "l": "regulation of IP-10 production", "d": ["Any process that modulates the frequency, rate, or extent of production of IP-10."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071640", "l": "regulation of macrophage inflammatory protein 1 alpha production", "d": ["Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021770", "l": "parahippocampal gyrus development", "d": ["The progression of the parahippocampal gyrus over time from its initial formation until its mature state. The parahippocampal gyrus is a ridge in the cerebral cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901082", "l": "positive regulation of relaxation of smooth muscle", "d": ["Any process that activates or increases the frequency, rate or extent of relaxation of smooth muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042848", "l": "sorbose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019640", "l": "glucuronate catabolic process to xylulose 5-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of glucuronate into other compounds, including xylulose 5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000306", "l": "positive regulation of photomorphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of photomorphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010967", "l": "regulation of polyamine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of polyamine biosynthesis. Polyamine biosynthesis is the chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072746", "l": "cellular response to tetracycline", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904205", "l": "negative regulation of skeletal muscle hypertrophy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901539", "l": "ent-pimara-8(14),15-diene metabolic process", "d": ["The chemical reactions and pathways involving ent-pimara-8(14),15-diene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904677", "l": "positive regulation of somatic stem cell division", "d": ["Any process that activates or increases the frequency, rate or extent of somatic stem cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0031170", "l": "ferricrocin metabolic process", "d": ["The chemical reactions and pathways involving ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021962", "l": "vestibulospinal tract morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006747", "l": "FAD biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of FAD, the oxidized form of flavin-adenine dinucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030960", "l": "peptide cross-linking via 3'-(O4'-L-tyrosinyl)-L-tyrosine", "d": ["The modification of two peptidyl-tyrosines to form a 3'-(O4'-L-tyrosinyl)-L-tyrosine protein cross-link."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090264", "l": "regulation of immune complex clearance by monocytes and macrophages", "d": ["Any process that modulates the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030574", "l": "collagen catabolic process", "d": ["The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002238", "l": "response to molecule of fungal origin", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0099547", "l": "regulation of translation at synapse, modulating synaptic transmission", "d": ["Any process that modulates synaptic transmission by regulating translation occurring at the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905118", "l": "positive regulation of ribonucleoside-diphosphate reductase activity", "d": ["Any process that activates or increases the frequency, rate or extent of ribonucleoside-diphosphate reductase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021926", "l": "Golgi cell precursor proliferation", "d": ["The multiplication or reproduction of neuroblasts that will give rise to Golgi cells. A Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990692", "l": "trans-Golgi-derived vesicle fusion with Golgi medial cisterna membrane", "d": ["The joining of the lipid bilayer membrane around a trans-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036493", "l": "positive regulation of translation in response to endoplasmic reticulum stress", "d": ["Any process that activates, or increases the frequency, rate or extent of translation as a result of endoplasmic reticulum stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090455", "l": "ornithine transmembrane import into vacuole", "d": ["The directed movement of ornithine into the vacuole across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010969", "l": "regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion", "d": ["Any process that modulates the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0042551", "l": "neuron maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046362", "l": "ribitol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0045493", "l": "xylan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of xylan, a polymer containing a beta-1,4-linked D-xylose backbone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.465174152298118", "identifiers": [{"i": "GO:0007560", "l": "imaginal disc morphogenesis", "d": ["The process in which the anatomical structures derived from an imaginal disc are generated and organized. The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075505", "l": "entry of intact viral capsid into host nucleus through nuclear pore complex", "d": ["Viral penetration into the host nucleus where a viral capsid passes intact through the host nuclear pore complex (NPC)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000848", "l": "positive regulation of corticosteroid hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of corticosteroid hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0034332", "l": "adherens junction organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060050", "l": "positive regulation of protein glycosylation", "d": ["Any process that activates or increases the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035676", "l": "anterior lateral line neuromast hair cell development", "d": ["The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019391", "l": "glucuronoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902732", "l": "positive regulation of chondrocyte proliferation", "d": ["Any process that increases the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051882", "l": "mitochondrial depolarization", "d": ["The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035553", "l": "oxidative single-stranded RNA demethylation", "d": ["Removal of the methyl group from one or more nucleotides within a single-stranded RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034177", "l": "positive regulation of toll-like receptor 12 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 12 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901307", "l": "positive regulation of spermidine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of spermidine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061105", "l": "regulation of stomach neuroendocrine cell differentiation", "d": ["Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:1901950", "l": "dense core granule transport", "d": ["The directed movement a dense core granule within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0010611", "l": "regulation of cardiac muscle hypertrophy", "d": ["Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0048573", "l": "photoperiodism, flowering", "d": ["A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light or dark of a given length. The length of the period of light or dark required to initiate the change is set relative to a particular duration known as the 'critical day length'. The critical day length varies between species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0072051", "l": "juxtaglomerular apparatus development", "d": ["The process whose specific outcome is the progression of the juxtaglomerular apparatus over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure that lies adjacent to the glomerulus and regulates kidney function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0097476", "l": "spinal cord motor neuron migration", "d": ["The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901015", "l": "3alpha(S)-strictosidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 3alpha(S)-strictosidine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072303", "l": "positive regulation of glomerular metanephric mesangial cell proliferation", "d": ["Any process that increases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042672", "l": "retinal cone cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0018970", "l": "toluene metabolic process", "d": ["The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products such as gasoline and commonly used as a paint thinning agent and in other solvent applications."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060239", "l": "positive regulation of signal transduction involved in conjugation with cellular fusion", "d": ["Any process that increases the rate, frequency or extent of signal transduction involved in conjugation with cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0003164", "l": "His-Purkinje system development", "d": ["The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0006482", "l": "protein demethylation", "d": ["The removal of a methyl group, from a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903346", "l": "positive regulation of protein polyglycylation", "d": ["Any process that activates or increases the frequency, rate or extent of protein polyglycylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071031", "l": "nuclear mRNA surveillance of mRNA 3'-end processing", "d": ["The set of processes involved in identifying and degrading mRNAs with incorrectly formed 3'-ends within the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090687", "l": "activation of meiosis I spindle assembly checkpoint", "d": ["Any process that starts the inactive process of a meiosis I cell cycle spindle assembly checkpoint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007287", "l": "Nebenkern assembly", "d": ["Fusion of mitochondria during insect spermatid differentiation to form two masses, which wrap around each other to form a densely packed sphere called the Nebenkern."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904774", "l": "negative regulation of ubiquinone biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ubiquinone biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051102", "l": "DNA ligation involved in DNA recombination", "d": ["The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902268", "l": "negative regulation of polyamine transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of polyamine transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0070127", "l": "tRNA aminoacylation for mitochondrial protein translation", "d": ["The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046369", "l": "galactose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of galactose, the aldohexose galacto-hexose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0060055", "l": "angiogenesis involved in wound healing", "d": ["Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0031580", "l": "membrane raft distribution", "d": ["The process that establishes the spatial arrangement of membrane rafts within a cellular membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904267", "l": "negative regulation of Schwann cell chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014019", "l": "neuroblast development", "d": ["The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902005", "l": "regulation of proline biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of proline biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901530", "l": "response to hypochlorite", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hypochlorite stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070233", "l": "negative regulation of T cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000425", "l": "pexophagy", "d": ["The selective autophagy process in which a peroxisome is degraded by macroautophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0098930", "l": "axonal transport", "d": ["The directed movement of organelles or molecules along microtubules in axons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007427", "l": "epithelial cell migration, open tracheal system", "d": ["The orderly movement of epithelial cells during development of an open tracheal system. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061030", "l": "epithelial cell differentiation involved in mammary gland alveolus development", "d": ["The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.235616146829116", "identifiers": [{"i": "GO:0045787", "l": "positive regulation of cell cycle", "d": ["Any process that activates or increases the rate or extent of progression through the cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051645", "l": "Golgi localization", "d": ["Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905861", "l": "intranuclear rod assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an intranuclear rod."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090089", "l": "regulation of dipeptide transport", "d": ["Any process that modulates the rate, frequency or extent of dipeptide transport. Dipeptide transport is the directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902637", "l": "neural crest cell differentiation involved in thymus development", "d": ["Any neural crest cell differentiation that is involved in thymus development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0070050", "l": "neuron cellular homeostasis", "d": ["The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046832", "l": "negative regulation of RNA export from nucleus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902310", "l": "positive regulation of peptidyl-serine dephosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of peptidyl-serine dephosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0030999", "l": "linear element assembly", "d": ["The cell cycle process in which linear elements are assembled in association with fission yeast chromosomes during meiotic prophase. Linear element assembly begins with LinE complex formation and ends when LinE complexes are associated with chromatin in structures visible as nuclear foci. A linear element is a proteinaceous scaffold related to the synaptonemal complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903650", "l": "negative regulation of cytoplasmic transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902140", "l": "response to inositol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021851", "l": "neuroblast division in dorsal lateral ganglionic eminence", "d": ["The division of neuroblasts in the dorsal region of the lateral ganglionic eminence. These cells give rise to embryonic interneuron precursors that will migrate tangentially to the olfactory bulb."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010994", "l": "free ubiquitin chain polymerization", "d": ["The process of creating free ubiquitin chains, compounds composed of a large number of ubiquitin monomers. These chains are not conjugated to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045914", "l": "negative regulation of catecholamine metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905494", "l": "negative regulation of G-quadruplex DNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901727", "l": "positive regulation of histone deacetylase activity", "d": ["Any process that activates or increases the frequency, rate or extent of histone deacetylase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032255", "l": "maintenance of secretory granule location", "d": ["Any process in which a secretory granule is maintained in a specific location within a cell and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018985", "l": "pronuclear envelope synthesis", "d": ["Synthesis and ordering of the envelope of pronuclei."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045594", "l": "positive regulation of cumulus cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of ovarian cumulus cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.99325467562582", "identifiers": [{"i": "GO:0046879", "l": "hormone secretion", "d": ["The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900688", "l": "positive regulation of gerfelin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of gerfelin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002853", "l": "negative regulation of T cell mediated cytotoxicity directed against tumor cell target", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001178", "l": "regulation of transcriptional start site selection at RNA polymerase II promoter", "d": ["Any process that modulates the rate, frequency or extent of a process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043309", "l": "regulation of eosinophil degranulation", "d": ["Any process that modulates the frequency, rate, or extent of eosinophil degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046664", "l": "dorsal closure, amnioserosa morphology change", "d": ["The changes that occur during dorsal closure of the shape and structure of the amnioserosa, an epithelium that occupies the dorsal side of the embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021961", "l": "posterior commissure morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901497", "l": "response to diphenyl ether", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenyl ether stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990539", "l": "fructose import across plasma membrane", "d": ["The directed movement of fructose substance from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:2001023", "l": "regulation of response to drug", "d": ["Any process that modulates the frequency, rate or extent of response to drug."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071803", "l": "positive regulation of podosome assembly", "d": ["Any process that activates or increases the rate or extent of podosome assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007075", "l": "positive regulation of transcription involved in exit from mitosis, from RNA polymerase III promoter", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase III promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.029198101185301", "identifiers": [{"i": "GO:0061535", "l": "glutamate secretion, neurotransmission", "d": ["The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018140", "l": "peptide cross-linking via L-cysteine thiazolecarboxylic acid", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl cysteine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048917", "l": "posterior lateral line ganglion development", "d": ["The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090082", "l": "positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of canonical Wnt signaling pathway that positively regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902158", "l": "positive regulation of response to G2 DNA damage checkpoint signaling", "d": ["Any process that activates or increases the frequency, rate or extent of response to G2 DNA damage checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0080028", "l": "nitrile biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900940", "l": "positive regulation of (Z)-nonadeca-1,14-diene metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072229", "l": "metanephric proximal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002365", "l": "gamma-delta T cell lineage commitment", "d": ["The process in which a pro-T cell becomes committed to becoming a gamma-delta T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000259", "l": "positive regulation of protein activation cascade", "d": ["Any process that activates or increases the frequency, rate or extent of protein activation cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072695", "l": "regulation of DNA recombination at telomere", "d": ["Any process that modulates the frequency, rate or extent of DNA recombination within the telomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905336", "l": "negative regulation of aggrephagy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aggrephagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002878", "l": "negative regulation of acute inflammatory response to non-antigenic stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033370", "l": "maintenance of protein location in mast cell secretory granule", "d": ["A process in which a protein is maintained in a secretory granule in a mast cell and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046956", "l": "positive phototaxis", "d": ["The directed movement of a cell or organism towards a source of light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051554", "l": "flavonol metabolic process", "d": ["The chemical reactions and pathways involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0140131", "l": "positive regulation of lymphocyte chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of lymphocyte chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035937", "l": "estrogen secretion", "d": ["The regulated release of estrogen into the circulatory system. Estrogen is a steroid hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044741", "l": "envenomation resulting in negative regulation of sensory perception of pain in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the sensory perception of pain in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001226", "l": "negative regulation of chloride transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chloride transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060670", "l": "branching involved in labyrinthine layer morphogenesis", "d": ["The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051877", "l": "pigment granule aggregation in cell center", "d": ["The directed movement of dispersed pigment granules towards the center of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051159", "l": "D-arabitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0061037", "l": "negative regulation of cartilage development", "d": ["Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900658", "l": "regulation of emericellamide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of emericellamide biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045572", "l": "positive regulation of imaginal disc growth", "d": ["Any process that activates or increases the frequency, rate or extent of imaginal disc growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019232", "l": "perception of rate of movement", "d": ["The series of events by which an organism senses the speed and direction of movement of the body and its parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000971", "l": "negative regulation of detection of glucose", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of detection of glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901854", "l": "5,6,7,8-tetrahydrosarcinapterin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydrosarcinapterin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.438480474645189", "identifiers": [{"i": "GO:0070925", "l": "organelle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000471", "l": "regulation of hematopoietic stem cell migration", "d": ["Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0034094", "l": "regulation of maintenance of meiotic sister chromatid cohesion", "d": ["Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.303328383464915", "identifiers": [{"i": "GO:0042044", "l": "fluid transport", "d": ["The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0006141", "l": "regulation of purine nucleobase metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving purines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.622337805354121", "identifiers": [{"i": "GO:0031348", "l": "negative regulation of defense response", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0043938", "l": "positive regulation of sporulation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033514", "l": "L-lysine catabolic process to acetyl-CoA via L-pipecolate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate L-pipecolate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033347", "l": "tetrose metabolic process", "d": ["The chemical reactions and pathways involving a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905518", "l": "regulation of presynaptic active zone assembly", "d": ["Any process that modulates the frequency, rate or extent of presynaptic active zone assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006283", "l": "transcription-coupled nucleotide-excision repair", "d": ["The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033617", "l": "mitochondrial cytochrome c oxidase assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032082", "l": "negative regulation of type III site-specific deoxyribonuclease activity", "d": ["Any process that stops or reduces the rate of type III restriction endodeoxyribonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071271", "l": "1-butanol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 1-butanol, an alkyl primary alcohol with the formula C4H10O."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062210", "l": "shoot regeneration", "d": ["The regeneration process by which a damaged or lost shoot regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to produce a new shoot meristem and subsequently a new shoot."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.51677448868422", "identifiers": [{"i": "GO:0015031", "l": "protein transport", "d": ["The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000164", "l": "negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090074", "l": "negative regulation of protein homodimerization activity", "d": ["Any process that decreases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048897", "l": "myelination of lateral line nerve axons", "d": ["The formation of compact myelin sheaths around the axons of a lateral line nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036109", "l": "alpha-linolenic acid metabolic process", "d": ["The chemical reactions and pathways involving alpha-linolenic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903928", "l": "cellular response to cyanide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0038010", "l": "positive regulation of signal transduction by receptor internalization", "d": ["Any process in which the internalization of a signaling receptor activates or increases the frequency, rate or extent of signal transduction. Receptor internalization can enhance signaling by concentrating signaling molecules in one location, or by moving a ligand-activated receptor to the location of downstream signaling proteins. Endosomes for example can serve as important intracellular signaling platforms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1901881", "l": "positive regulation of protein depolymerization", "d": ["Any process that activates or increases the frequency, rate or extent of protein depolymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001187", "l": "positive regulation of CD8-positive, alpha-beta T cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006065", "l": "UDP-glucuronate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0002708", "l": "positive regulation of lymphocyte mediated immunity", "d": ["Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090546", "l": "chlorophyll fluorescence", "d": ["The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is re-emitted as light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0086021", "l": "SA node cell to atrial cardiac muscle cell communication by electrical coupling", "d": ["The process that mediates signaling interactions between an SA node cardiomyocyte and an atrial cardiomyocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090517", "l": "L-lysine transmembrane import into vacuole", "d": ["The directed movement of L-lysine into the vacuole across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080163", "l": "regulation of protein serine/threonine phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of protein serine/threonine phosphatase activity: catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048912", "l": "glial cell migration in anterior lateral line nerve", "d": ["The movement of a glial cell along the axons in the anterior lateral line nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140214", "l": "positive regulation of long-chain fatty acid import into cell", "d": ["Any process that activates or increases the frequency, rate or extent of long-chain fatty acid import into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046413", "l": "organomercury catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of organomercury compounds, any organic compound containing a mercury atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021642", "l": "trochlear nerve formation", "d": ["The process that gives rise to the trochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.919848880058524", "identifiers": [{"i": "GO:0060004", "l": "reflex", "d": ["An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0055062", "l": "phosphate ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060470", "l": "positive regulation of cytosolic calcium ion concentration involved in egg activation", "d": ["The process that increases the concentration of calcium ions in the cytosol after fertilization or the physiological activation of an egg."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0019080", "l": "viral gene expression", "d": ["A process by which a viral gene is converted into a mature gene product or products (proteins or RNA). This includes viral transcription, processing to produce a mature RNA product, and viral translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:1900047", "l": "negative regulation of hemostasis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044833", "l": "modulation by virus of host protein transport", "d": ["Any viral process that modulates the frequency, rate or extent of protein transport in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035469", "l": "determination of pancreatic left/right asymmetry", "d": ["Determination of the asymmetric location of the pancreas with respect to the left and right halves of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150176", "l": "positive regulation of phosphatidylethanolamine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylethanolamine metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031456", "l": "glycine betaine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycine betaine, N-trimethylglycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033672", "l": "positive regulation of NAD+ kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0010118", "l": "stomatal movement", "d": ["The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061109", "l": "dense core granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006436", "l": "tryptophanyl-tRNA aminoacylation", "d": ["The process of coupling tryptophan to tryptophanyl-tRNA, catalyzed by tryptophanyl-tRNA synthetase. The tryptophanyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tryptophan-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015946", "l": "methanol oxidation", "d": ["The chemical reactions and pathways resulting in the conversion of methanol to methyl-Coenzyme M."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021703", "l": "locus ceruleus development", "d": ["The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001879", "l": "detection of yeast", "d": ["The series of events in which a stimulus from a yeast is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0010332", "l": "response to gamma radiation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.473441072356337", "identifiers": [{"i": "GO:0007507", "l": "heart development", "d": ["The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0033622", "l": "integrin activation", "d": ["The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001814", "l": "negative regulation of antibody-dependent cellular cytotoxicity", "d": ["Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902265", "l": "abscisic acid homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of abscisic acid within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035387", "l": "negative regulation of Roundabout signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the Roundabout signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007055", "l": "spindle assembly involved in male meiosis II", "d": ["The formation of the spindle during meiosis II of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035522", "l": "monoubiquitinated histone H2A deubiquitination", "d": ["The removal of the ubiquitin group from a monoubiquitinated histone H2A protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061388", "l": "regulation of rate of cell growth", "d": ["Any process that modulates the rate of cell growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002108", "l": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)", "d": ["Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902759", "l": "Mo(VI)-molybdopterin cytosine dinucleotide metabolic process", "d": ["The chemical reactions and pathways involving Mo(VI)-molybdopterin cytosine dinucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0018279", "l": "protein N-linked glycosylation via asparagine", "d": ["The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060435", "l": "bronchiole development", "d": ["The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000097", "l": "regulation of smooth muscle cell-matrix adhesion", "d": ["Any process that modulates the frequency, rate or extent of smooth muscle cell-matrix adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900209", "l": "negative regulation of cardiolipin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiolipin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0046885", "l": "regulation of hormone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032491", "l": "detection of molecule of fungal origin", "d": ["The series of events in which a stimulus from a molecule of fungal origin is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010891", "l": "negative regulation of sequestering of triglyceride", "d": ["Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006230", "l": "TMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of TMP, ribosylthymine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002093", "l": "auditory receptor cell morphogenesis", "d": ["Any process that alters the size or shape of an auditory receptor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902809", "l": "regulation of skeletal muscle fiber differentiation", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905864", "l": "regulation of Atg1/ULK1 kinase complex assembly", "d": ["Any process that modulates the frequency, rate or extent of Atg1/ULK1 kinase complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042636", "l": "negative regulation of hair cycle", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000642", "l": "negative regulation of early endosome to late endosome transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of early endosome to late endosome transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.044281719092751", "identifiers": [{"i": "GO:0044848", "l": "biological phase", "d": ["A distinct period or stage in a biological process or cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015777", "l": "teichoic acid transport", "d": ["The directed movement of teichoic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Teichoic acid is any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071638", "l": "negative regulation of monocyte chemotactic protein-1 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of monocyte chemotactic protein-1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048874", "l": "host-mediated regulation of intestinal microbiota composition", "d": ["The biological process involved in maintaining the steady-state number of cells within a population of free-living cells such as the bacteria in the gut."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0046485", "l": "ether lipid metabolic process", "d": ["The chemical reactions and pathways involving ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075222", "l": "sporangium germination", "d": ["The physiological, developmental and morphological changes that occur in a symbiont sporangium following release from dormancy up to the earliest signs of growth. A sporangium is a structure producing and containing spores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0007630", "l": "jump response", "d": ["The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042213", "l": "m-cresol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of m-cresol (3-hydroxytoluene), the meta-isoform of cresol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070543", "l": "response to linoleic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021673", "l": "rhombomere 7 formation", "d": ["The process that gives rise to rhombomere 7. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060879", "l": "semicircular canal fusion", "d": ["Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms during the process of semicircular canal formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902138", "l": "(-)-secoisolariciresinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (-)-secoisolariciresinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000945", "l": "regulation of amylopectin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of amylopectin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042207", "l": "styrene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of styrene, an aromatic hydrocarbon liquid used in the manufacture of polystyrene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014905", "l": "myoblast fusion involved in skeletal muscle regeneration", "d": ["A process in which non-proliferating myoblasts, after migrating to the site of injury, fuse into existing damaged fibers or fuse to myotubes to form new fibers, as part of the process of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070076", "l": "histone lysine demethylation", "d": ["The modification of a histone by the removal of a methyl group from a lysine residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046230", "l": "2-aminobenzenesulfonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900761", "l": "averantin metabolic process", "d": ["The chemical reactions and pathways involving averantin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904426", "l": "positive regulation of GTP binding", "d": ["Any process that activates or increases the frequency, rate or extent of GTP binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098706", "l": "iron ion import across cell outer membrane", "d": ["The directed movement of iron ions from outside of a cell, across the cell outer membrane and into the periplasmic space."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905638", "l": "negative regulation of mitochondrial mRNA catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial mRNA catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007054", "l": "spindle assembly involved in male meiosis I", "d": ["The formation of the spindle during meiosis I of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904971", "l": "regulation of viral translation", "d": ["Any process that modulates the frequency, rate or extent of viral translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0014073", "l": "response to tropane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009432", "l": "SOS response", "d": ["An error-prone process for repairing damaged microbial DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060529", "l": "squamous basal epithelial stem cell differentiation involved in prostate gland acinus development", "d": ["The process in which a relatively unspecialized epithelial cell acquires specialized features of a squamous basal epithelial stem cell of the prostate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000449", "l": "endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)", "d": ["Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. For example, primary ribosomal RNA transcripts containing three genes, in this order, are produced in E. coli and other prokaryotic species. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1904594", "l": "regulation of termination of RNA polymerase II transcription", "d": ["Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0050893", "l": "sensory processing", "d": ["Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0019432", "l": "triglyceride biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0007501", "l": "mesodermal cell fate specification", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.240853996207278", "identifiers": [{"i": "GO:0022409", "l": "positive regulation of cell-cell adhesion", "d": ["Any process that activates or increases the rate or extent of cell adhesion to another cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044181", "l": "filamentous growth of a multicellular organism", "d": ["The process in which a multicellular organism grows in a threadlike, filamentous shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033246", "l": "positive regulation of penicillin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904702", "l": "regulation of protein localization to adherens junction", "d": ["Any process that modulates the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903141", "l": "negative regulation of establishment of endothelial barrier", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of endothelial barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0006083", "l": "acetate metabolic process", "d": ["The chemical reactions and pathways involving acetate, the anion of acetic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034155", "l": "regulation of toll-like receptor 7 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 7 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0043369", "l": "CD4-positive or CD8-positive, alpha-beta T cell lineage commitment", "d": ["The process in which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive lineage of alpha-beta T cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098784", "l": "biofilm matrix organization", "d": ["A process that results in the assembly, arrangement of constituent parts, or disassembly of a biofilm matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903191", "l": "glyoxal biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glyoxal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036279", "l": "positive regulation of protein export from nucleus in response to glucose starvation", "d": ["Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm in response to deprivation of glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051695", "l": "actin filament uncapping", "d": ["The removal of capping protein from the end of actin filaments to free the ends for addition, exchange or removal of further actin subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019564", "l": "aerobic glycerol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, in the presence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019736", "l": "peptidyl-sarcosine incorporation", "d": ["The incorporation of sarcosine (N-methylglycine) into non-coded peptides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035232", "l": "germ cell attraction", "d": ["The directed movement of a germ cell from their site of production to the gonad, through the attraction of cells towards their target."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901398", "l": "regulation of transforming growth factor beta3 activation", "d": ["Any process that modulates the frequency, rate or extent of transforming growth factor beta3 activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0043063", "l": "intercellular bridge organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the intracellular bridge. An intracellular bridge is a direct link between the cytoplasms of sister cells that allows cells to communicate with one another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905146", "l": "lysosomal protein catabolic process", "d": ["Any cellular protein catabolic process that takes place in a lysosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009214", "l": "cyclic nucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075330", "l": "positive regulation of arbuscule formation for nutrient acquisition from host", "d": ["Any process that activates or increases the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:1902275", "l": "regulation of chromatin organization", "d": ["Any process that modulates the frequency, rate or extent of chromatin organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002491", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class II", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061131", "l": "pancreas field specification", "d": ["The process in which a specific region of the gut is delineated into the area in which the pancreas will develop."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010028", "l": "xanthophyll cycle", "d": ["A cyclic series of interconversions involving three xanthophylls, violoxanthin, antheraxanthin, and zeaxanthin. The xanthophyll cycle is involved in regulating energy dissipation in light harvesting complex II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035678", "l": "neuromast hair cell morphogenesis", "d": ["The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902957", "l": "negative regulation of mitochondrial electron transport, NADH to ubiquinone", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051070", "l": "galactomannan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046070", "l": "dGTP metabolic process", "d": ["The chemical reactions and pathways involving dGTP, guanosine triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901895", "l": "negative regulation of ATPase-coupled calcium transmembrane transporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060720", "l": "spongiotrophoblast cell proliferation", "d": ["The multiplication or reproduction of spongiotrophoblast cells, resulting in the expansion of the population in the spongiotrophoblast layer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019479", "l": "L-alanine oxidation to D-lactate and ammonia", "d": ["The chemical reactions and pathways resulting in the breakdown of L-alanine to D-lactate and ammonia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0001171", "l": "reverse transcription", "d": ["A DNA synthesis process that uses RNA as the initial template for synthesis of DNA, but which also includes an RNase activity to remove the RNA strand of an RNA-DNA heteroduplex produced by the RNA-dependent synthesis step and use of the initial DNA strand as a template for DNA synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006097", "l": "glyoxylate cycle", "d": ["A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.281967957033203", "identifiers": [{"i": "GO:0006979", "l": "response to oxidative stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042810", "l": "pheromone metabolic process", "d": ["The chemical reactions and pathways involving pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110120", "l": "gamma-tubulin complex localization to nuclear side of mitotic spindle pole body", "d": ["Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the nuclear side of the mitotic spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0003279", "l": "cardiac septum development", "d": ["The progression of a cardiac septum over time, from its initial formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0002204", "l": "somatic recombination of immunoglobulin genes involved in immune response", "d": ["The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of and contributing to an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0019448", "l": "L-cysteine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035334", "l": "Notch receptor processing, ligand-independent", "d": ["The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1905710", "l": "positive regulation of membrane permeability", "d": ["Any process that activates or increases the frequency, rate or extent of the passage or uptake of molecules by a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006883", "l": "intracellular sodium ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of sodium ions within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060196", "l": "positive regulation of antisense RNA transcription", "d": ["Any process that increases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905513", "l": "negative regulation of short-term synaptic potentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of short-term synaptic potentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0031052", "l": "programmed DNA elimination by chromosome breakage", "d": ["Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0048229", "l": "gametophyte development", "d": ["The process whose specific outcome is the progression of the gametophyte over time, from its formation to the mature structure. The gametophyte is the gamete-producing individual or phase in the life cycle having alternation of generations. An example of this process is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032247", "l": "negative regulation of purine nucleoside transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.773387538292397", "identifiers": [{"i": "GO:0072527", "l": "pyrimidine-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035190", "l": "syncytial nuclear migration", "d": ["The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0043242", "l": "negative regulation of protein-containing complex disassembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905338", "l": "negative regulation of cohesin unloading", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cohesin unloading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140920", "l": "regulation of thermomorphogenesis", "d": ["Any process that modulates the frequency, rate or extent of thermomorphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014736", "l": "negative regulation of muscle atrophy", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle atrophy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1900117", "l": "regulation of execution phase of apoptosis", "d": ["Any process that modulates the frequency, rate or extent of execution phase of apoptosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045542", "l": "positive regulation of cholesterol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038032", "l": "termination of G protein-coupled receptor signaling pathway", "d": ["The signaling process in which G protein-coupled receptor signaling is brought to an end. For example, through the action of GTPase-activating proteins (GAPs) that act to accelerate hydrolysis of GTP to GDP on G-alpha proteins, thereby terminating the transduced signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.644186068201407", "identifiers": [{"i": "GO:0140546", "l": "defense response to symbiont", "d": ["Reactions triggered in response to the presence of a symbiont that act to protect the cell or organism from damage caused by that symbiont."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0003068", "l": "regulation of systemic arterial blood pressure by acetylcholine", "d": ["The regulation of blood pressure mediated by acetylcholine signaling. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010056", "l": "atrichoblast fate specification", "d": ["The process involved in the specification of an atrichoblast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000304", "l": "positive regulation of ceramide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ceramide biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032719", "l": "negative regulation of TRAIL production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of TRAIL production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900596", "l": "(+)-kotanin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (+)-kotanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0000085", "l": "mitotic G2 phase", "d": ["The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048348", "l": "paraxial mesodermal cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043644", "l": "tetracycline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0006893", "l": "Golgi to plasma membrane transport", "d": ["The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0005994", "l": "melibiose metabolic process", "d": ["The chemical reactions and pathways involving melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150127", "l": "regulation of interleukin-33 production", "d": ["Any process that modulates the frequency, rate or extent of interleukin-33 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045687", "l": "positive regulation of glial cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of glia cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021507", "l": "posterior neuropore closure", "d": ["The joining together of the neural folds of the caudal opening of the neural tube. The posterior neuropore appears before the process of neural tube closure is complete."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.825466069370655", "identifiers": [{"i": "GO:0006486", "l": "protein glycosylation", "d": ["A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010027", "l": "thylakoid membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the thylakoid membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006042", "l": "glucosamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000447", "l": "negative regulation of macrophage migration inhibitory factor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048458", "l": "floral whorl formation", "d": ["The process that gives rise to the floral whorl. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061519", "l": "macrophage homeostasis", "d": ["The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0075260", "l": "regulation of spore-bearing organ development", "d": ["Any process that modulates the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.141482614631713", "identifiers": [{"i": "GO:0031349", "l": "positive regulation of defense response", "d": ["Any process that activates or increases the frequency, rate or extent of a defense response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045886", "l": "negative regulation of synaptic assembly at neuromuscular junction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic assembly at neuromuscular junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010396", "l": "rhamnogalacturonan II metabolic process", "d": ["The chemical reactions and pathways involving rhamnogalacturonan II, a low molecular mass (5-10KDa) pectic polysaccharide. The backbone of RG-II contains at least 8 1,4-linked alpha-D-GalpA residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036160", "l": "melanocyte-stimulating hormone secretion", "d": ["The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000918", "l": "regulation of glucuronoarabinoxylan catabolic process", "d": ["Any process that modulates the frequency, rate or extent of glucuronoarabinoxylan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0070486", "l": "leukocyte aggregation", "d": ["The adhesion of one leukocyte to one or more other leukocytes via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905081", "l": "positive regulation of cerebellar neuron development", "d": ["Any process that activates or increases the frequency, rate or extent of cerebellar neuron development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0090672", "l": "telomerase RNA localization", "d": ["Any process in which telomerase RNA is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902933", "l": "isopentenol metabolic process", "d": ["The chemical reactions and pathways involving isopentenol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006052", "l": "N-acetylmannosamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903501", "l": "positive regulation of mitotic actomyosin contractile ring assembly", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044866", "l": "modulation by host of viral exo-alpha-sialidase activity", "d": ["The process in which a host organism effects a change in viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905692", "l": "endoplasmic reticulum disassembly", "d": ["The disaggregation of an endoplasmic reticulum into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019451", "l": "L-cysteine catabolic process to pyruvate, using cysteine dioxygenase", "d": ["The chemical reactions and pathways resulting in the breakdown into pyruvate of L-cystine, catalyzed by the enzyme cysteine dioxygenase (EC:1.13.11.20)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0043616", "l": "keratinocyte proliferation", "d": ["The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903379", "l": "regulation of mitotic chromosome condensation", "d": ["Any process that modulates the frequency, rate or extent of mitotic chromosome condensation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070965", "l": "positive regulation of neutrophil mediated killing of fungus", "d": ["Any process that increases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905788", "l": "negative regulation of detection of mechanical stimulus involved in sensory perception of touch", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903252", "l": "hercynylcysteine sulfoxide metabolic process", "d": ["The chemical reactions and pathways involving hercynylcysteine sulfoxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046375", "l": "K antigen metabolic process", "d": ["The chemical reactions and pathways involving K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019546", "l": "arginine deiminase pathway", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine and CO2, using the enzyme arginine deiminase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902977", "l": "mitotic DNA replication preinitiation complex assembly", "d": ["Any DNA replication preinitiation complex assembly that is involved in mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990000", "l": "amyloid fibril formation", "d": ["The generation of amyloid fibrils, insoluble fibrous protein aggregates exhibiting beta sheet structure, from proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000837", "l": "regulation of androstenedione secretion", "d": ["Any process that modulates the frequency, rate or extent of androstenedione secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070101", "l": "positive regulation of chemokine-mediated signaling pathway", "d": ["Any process that increases the rate, frequency or extent of a chemokine-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0022601", "l": "menstrual cycle phase", "d": ["The progression of physiological phases, occurring in the endometrium during the menstrual cycle that recur at regular intervals during the reproductive years. The menstrual cycle is an ovulation cycle where the endometrium is shed if pregnancy does not occur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090428", "l": "perianth development", "d": ["The process whose specific outcome is the progression of the perianth over time, from its formation to the mature structure. The perianth is a collective phyllome structure composed of two or more petals, sepals, or tepals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0016116", "l": "carotenoid metabolic process", "d": ["The chemical reactions and pathways involving carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905140", "l": "regulation of apical ectodermal ridge formation", "d": ["Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000096", "l": "positive regulation of Wnt signaling pathway, planar cell polarity pathway", "d": ["Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000337", "l": "positive regulation of endothelial microparticle formation", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial microparticle formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097267", "l": "omega-hydroxylase P450 pathway", "d": ["The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034352", "l": "positive regulation of glial cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.07563785880906", "identifiers": [{"i": "GO:0032990", "l": "cell part morphogenesis", "d": ["The process in which the anatomical structures of a cell part are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003053", "l": "circadian regulation of heart rate", "d": ["Any process in which an organism modulates its heart rate at different values with a regularity of approximately 24 hours."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120304", "l": "integument-mediated background adaptation", "d": ["Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by light sensitive cells in the integument."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0043558", "l": "regulation of translational initiation in response to stress", "d": ["Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002724", "l": "regulation of T cell cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of T cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903961", "l": "positive regulation of anion transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of anion transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.712091546727706", "identifiers": [{"i": "GO:1990748", "l": "cellular detoxification", "d": ["Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042777", "l": "proton motive force-driven plasma membrane ATP synthesis", "d": ["The transport of protons across the plasma membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009185", "l": "ribonucleoside diphosphate metabolic process", "d": ["The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904028", "l": "positive regulation of collagen fibril organization", "d": ["Any process that activates or increases the frequency, rate or extent of collagen fibril organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0006306", "l": "DNA methylation", "d": ["The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900957", "l": "negative regulation of 17-methylnonadec-1-ene biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033610", "l": "oxalate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of oxalate, the organic acid ethanedioate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045110", "l": "intermediate filament bundle assembly", "d": ["The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0006596", "l": "polyamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070954", "l": "negative regulation of neutrophil mediated cytotoxicity", "d": ["Any process that decreases the frequency, rate or extent of the directed killing of a target cell by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032480", "l": "negative regulation of type I interferon production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007436", "l": "larval salivary gland morphogenesis", "d": ["The process, occurring in the larva, by which the anatomical structures of the salivary gland are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0007043", "l": "cell-cell junction assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a junction between cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0045665", "l": "negative regulation of neuron differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903493", "l": "response to clopidogrel", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clopidogrel stimulus. Clopidogrel is a is an oral, thienopyridine-class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019558", "l": "histidine catabolic process to 2-oxoglutarate", "d": ["The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including 2-oxoglutarate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010404", "l": "cell wall hydroxyproline-rich glycoprotein metabolic process", "d": ["The chemical reactions and pathways involving a cell wall hydroxyproline-rich glycoprotein that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072289", "l": "metanephric nephron tubule formation", "d": ["The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000227", "l": "negative regulation of pancreatic A cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019379", "l": "sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)", "d": ["The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905552", "l": "positive regulation of protein localization to endoplasmic reticulum", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0009079", "l": "pyruvate family amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any amino acid that requires pyruvate for its synthesis, e.g. alanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0007077", "l": "mitotic nuclear membrane disassembly", "d": ["The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046285", "l": "flavonoid phytoalexin metabolic process", "d": ["The chemical reactions and pathways involving flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "46.395205470171433", "identifiers": [{"i": "GO:0051649", "l": "establishment of localization in cell", "d": ["Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070171", "l": "negative regulation of tooth mineralization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.117553355927669", "identifiers": [{"i": "GO:0018193", "l": "peptidyl-amino acid modification", "d": ["The alteration of an amino acid residue in a peptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140925", "l": "L-phenylalanine import across plasma membrane", "d": ["The directed movement of L-phenylalanine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001893", "l": "maternal placenta development", "d": ["Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.284222931418633", "identifiers": [{"i": "GO:1901361", "l": "organic cyclic compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of organic cyclic compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000471", "l": "endonucleolytic cleavage in 3'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage within the 3'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, endonucleolytic cleavage within the 3'-ETS of the pre-RNA, which may occur cotranscriptionally, is the first step in rRNA processing, and initiates a cascade of subsequent processing and modification events."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0061008", "l": "hepaticobiliary system development", "d": ["The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006060", "l": "sorbitol metabolic process", "d": ["The chemical reactions and pathways involving sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0009166", "l": "nucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034234", "l": "regulation of ascospore wall chitin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of ascospore wall chitin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060386", "l": "synapse assembly involved in innervation", "d": ["The assembly of a synapse within a target tissue in which a nerve is invading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901303", "l": "negative regulation of cargo loading into COPII-coated vesicle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cargo loading into a COPII-coated vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902354", "l": "blood vessel endothelial cell delamination involved in blood vessel lumen ensheathment", "d": ["Any blood vessel endothelial cell delamination that is involved in blood vessel lumen ensheathment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033571", "l": "lactoferrin transport", "d": ["The directed movement of lactoferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075255", "l": "teliospore formation", "d": ["The set of processes leading to the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032288", "l": "myelin assembly", "d": ["The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035135", "l": "post-embryonic anal fin morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904400", "l": "response to Thyroid stimulating hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045952", "l": "regulation of juvenile hormone catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061924", "l": "regulation of formation of radial glial scaffolds", "d": ["Any process that modulates the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002002", "l": "regulation of angiotensin levels in blood", "d": ["The process that modulates the level of any of the various angiotensinogen proteolytic products in the blood. This occurs by the proteolytic cleavage of angiotensinogen, and its proteolytic products, to create a variety of active peptide hormones, such as angiotensin I and angiotensin II, as well as through the removal of these peptides from the circulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000953", "l": "positive regulation of xyloglucan catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of xyloglucan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090159", "l": "sphingolipid biosynthesis involved in endoplasmic reticulum membrane organization", "d": ["The chemical reactions and pathways resulting in the formation of sphingolipids that contributes to endoplasmic reticulum membrane organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.819009873417293", "identifiers": [{"i": "GO:0030097", "l": "hemopoiesis", "d": ["The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.767641576330163", "identifiers": [{"i": "GO:0061640", "l": "cytoskeleton-dependent cytokinesis", "d": ["A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048612", "l": "post-embryonic ectodermal digestive tract development", "d": ["The process, occurring during the post-embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1904376", "l": "negative regulation of protein localization to cell periphery", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:0050678", "l": "regulation of epithelial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of epithelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905745", "l": "negative regulation of mRNA cis splicing, via spliceosome", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cis splicing, via spliceosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017126", "l": "nucleologenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.362525179576039", "identifiers": [{"i": "GO:0051250", "l": "negative regulation of lymphocyte activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007182", "l": "common-partner SMAD protein phosphorylation", "d": ["The process of introducing a phosphate group on to a common-partner SMAD protein. A common partner SMAD protein binds to pathway-restricted SMAD proteins forming a complex that translocates to the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097474", "l": "retinal cone cell apoptotic process", "d": ["Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140133", "l": "suppression by symbiont of host cytokine production", "d": ["Any process in which a symbiont stops, prevents, or reduces the rate or extent of cytokine production by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033508", "l": "glutamate catabolic process to butyrate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including butyrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901942", "l": "(+)-epi-alpha-bisabolol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (+)-epi-alpha-bisabolol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.378105282841119", "identifiers": [{"i": "GO:0006869", "l": "lipid transport", "d": ["The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0050956", "l": "electroception", "d": ["The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010193", "l": "response to ozone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030007", "l": "intracellular potassium ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of potassium ions within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071727", "l": "cellular response to triacyl bacterial lipopeptide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0071774", "l": "response to fibroblast growth factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035476", "l": "angioblast cell migration", "d": ["The orderly movement of angioblasts, cells involved in blood vessel morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900682", "l": "octadecene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of octadecene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0044804", "l": "nucleophagy", "d": ["A form of autophagy, by which damaged or non-essential parts of the nucleus, or even an entire nucleus is degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0120034", "l": "positive regulation of plasma membrane bounded cell projection assembly", "d": ["Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001154", "l": "regulation of glycolytic fermentation to ethanol", "d": ["Any process that modulates the frequency, rate or extent of glucose catabolic process to ethanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902212", "l": "negative regulation of prolactin signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0043161", "l": "proteasome-mediated ubiquitin-dependent protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905656", "l": "positive regulation of artery smooth muscle contraction", "d": ["Any process that activates or increases the frequency, rate or extent of artery smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071465", "l": "cellular response to desiccation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902193", "l": "2-methylbut-2-enoyl-CoA(4-) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-methylbut-2-enoyl-CoA(4-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000239", "l": "pachytene", "d": ["The cell cycle phase which follows zygotene during prophase I of meiosis, and during which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0032906", "l": "transforming growth factor beta2 production", "d": ["The appearance of transforming growth factor-beta2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010672", "l": "regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle", "d": ["Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0009691", "l": "cytokinin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.545697013636541", "identifiers": [{"i": "GO:0071345", "l": "cellular response to cytokine stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0098765", "l": "meiosis II cell cycle phase", "d": ["A meiotic cell cycle phase that occurs after meiosis I (the first meiotic nuclear division)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000309", "l": "positive regulation of tumor necrosis factor (ligand) superfamily member 11 production", "d": ["Any process that activates or increases the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.426153789046865", "identifiers": [{"i": "GO:0009410", "l": "response to xenobiotic stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903566", "l": "positive regulation of protein localization to cilium", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to cilium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003426", "l": "cytoskeleton polarization involved in growth plate cartilage chondrocyte division", "d": ["A process that is carried out at the cellular level which results in the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904544", "l": "positive regulation of free ubiquitin chain polymerization", "d": ["Any process that activates or increases the frequency, rate or extent of free ubiquitin chain polymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901753", "l": "leukotriene A4 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of leukotriene A4."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0040025", "l": "vulval development", "d": ["The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002035", "l": "brain renin-angiotensin system", "d": ["The process in which an angiotensin-mediated signaling system present in the brain regulates the force with which blood passes through the circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:1903463", "l": "regulation of mitotic cell cycle DNA replication", "d": ["Any process that modulates the frequency, rate or extent of mitotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090323", "l": "prostaglandin secretion involved in immune response", "d": ["The regulated release of a prostaglandin that contributes to the immune response. Prostaglandins are a group of biologically active metabolites which contain a cyclopentane ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098905", "l": "regulation of bundle of His cell action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901327", "l": "response to tacrolimus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.139845358389962", "identifiers": [{"i": "GO:1902652", "l": "secondary alcohol metabolic process", "d": ["The chemical reactions and pathways involving secondary alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044278", "l": "cell wall disruption in another organism", "d": ["The disruption of the cell wall of another organism, leading to damage or temporary subversion of the cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903376", "l": "regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903667", "l": "regulation of chemorepellent activity", "d": ["Any process that modulates the frequency, rate or extent of chemorepellent activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070475", "l": "rRNA base methylation", "d": ["The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061949", "l": "regulation of premature acrosome loss", "d": ["Any process that modulates the rate, frequency or extent of the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0001949", "l": "sebaceous gland cell differentiation", "d": ["The process in which a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0140970", "l": "AIM2 inflammasome complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the AIM2 inflammasome complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070858", "l": "negative regulation of bile acid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0040002", "l": "collagen and cuticulin-based cuticle development", "d": ["Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1903969", "l": "regulation of response to macrophage colony-stimulating factor", "d": ["Any process that modulates the frequency, rate or extent of response to macrophage colony-stimulating factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0070592", "l": "cell wall polysaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a polysaccharide destined to form part of a cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0002784", "l": "regulation of antimicrobial peptide production", "d": ["Any process that modulates the frequency, rate, or extent of antimicrobial peptide production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080057", "l": "sepal vascular tissue pattern formation", "d": ["Vascular tissue pattern formation as it occurs in the sepal of vascular plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098885", "l": "modification of postsynaptic actin cytoskeleton", "d": ["Any process that modifies the structure of a postsynaptic actin cytoskeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0030316", "l": "osteoclast differentiation", "d": ["The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.528602276407113", "identifiers": [{"i": "GO:0023051", "l": "regulation of signaling", "d": ["Any process that modulates the frequency, rate or extent of a signaling process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006181", "l": "dGMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070245", "l": "positive regulation of thymocyte apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903010", "l": "regulation of bone development", "d": ["Any process that modulates the frequency, rate or extent of bone development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042437", "l": "indoleacetic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of indole-3-acetic acid, a compound which functions as a growth regulator in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0090288", "l": "negative regulation of cellular response to growth factor stimulus", "d": ["Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0033344", "l": "cholesterol efflux", "d": ["The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0010229", "l": "inflorescence development", "d": ["The process whose specific outcome is the progression of an inflorescence over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033271", "l": "myo-inositol phosphate transport", "d": ["The directed movement of any phosphorylated myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905555", "l": "positive regulation of blood vessel branching", "d": ["Any process that activates or increases the frequency, rate or extent of blood vessel branching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071929", "l": "alpha-tubulin acetylation", "d": ["The addition of an acetyl group to the lysine 40 residue of alpha-tubulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044131", "l": "negative regulation of development of symbiont in host", "d": ["Any process in which the symbiont stops, prevents or reduces its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052080", "l": "modulation by symbiont of host innate immune response MAPK kinase signaling", "d": ["Any process in which an organism modulates the frequency, rate or extent of a host MAP kinase-mediated signal transduction pathway during the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000480", "l": "endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage within the 5'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. Endonucleolytic cleavage within the 5'-ETS of the pre-RNA is conserved as one of the early steps of rRNA processing in all eukaryotes, but the specific position of cleavage is variable."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0045582", "l": "positive regulation of T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048824", "l": "pigment cell precursor differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a pigment cell precursor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006288", "l": "base-excision repair, DNA ligation", "d": ["The ligation by DNA ligase of DNA strands. Ligation occurs after polymerase action to fill the gap left by the action of endonucleases during base-excision repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0036294", "l": "cellular response to decreased oxygen levels", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060430", "l": "lung saccule development", "d": ["The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0006415", "l": "translational termination", "d": ["The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903120", "l": "protein localization to actin filament bundle", "d": ["A process in which a protein is transported to, or maintained in, the location of an actin filament bundle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021724", "l": "inferior raphe nucleus development", "d": ["The process whose specific outcome is the progression of the inferior raphe nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901929", "l": "alpha-copaene metabolic process", "d": ["The chemical reactions and pathways involving alpha-copaene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097068", "l": "response to thyroxine", "d": ["A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010477", "l": "response to sulfur dioxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036272", "l": "response to gemcitabine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gemcitabine stimulus. Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position, and is used as a drug in the treatment of various carcinomas."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070096", "l": "mitochondrial outer membrane translocase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a mitochondrial outer membrane translocase complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150032", "l": "positive regulation of protein localization to lysosome", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to lysosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0001100", "l": "negative regulation of exit from mitosis", "d": ["Any process involved in the inhibition of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.000891501185137", "identifiers": [{"i": "GO:0010383", "l": "cell wall polysaccharide metabolic process", "d": ["The chemical reactions and pathways involving cell wall polysaccharides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042495", "l": "detection of triacyl bacterial lipopeptide", "d": ["The series of events in which a triacylated bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Triacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of three acyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0034501", "l": "protein localization to kinetochore", "d": ["Any process in which a protein is transported to, or maintained at, the kinetochore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052643", "l": "chlorophyllide metabolic process", "d": ["The chemical reactions and pathways involving chlorophyllides, any chlorophyll lacking the terpenoid side chain such as phytyl or farnesyl."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904966", "l": "positive regulation of vitamin E biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of vitamin E biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0014048", "l": "regulation of glutamate secretion", "d": ["Any process that modulates the frequency, rate or extent of the controlled release of glutamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140904", "l": "cytoophidium organization", "d": ["A process which results in the assembly, arrangement of constituent parts, or disassembly of a cytoophidium. Cytoophidia are mesoscale, intracellular, filamentous structures that contain metabolic enzymes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042366", "l": "cobalamin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0070231", "l": "T cell apoptotic process", "d": ["Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061331", "l": "epithelial cell proliferation involved in Malpighian tubule morphogenesis", "d": ["The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.105947648851327", "identifiers": [{"i": "GO:0007049", "l": "cell cycle", "d": ["The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034126", "l": "positive regulation of MyD88-dependent toll-like receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905440", "l": "cellular response to chondroitin 6'-sulfate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.50898652134218", "identifiers": [{"i": "GO:0048066", "l": "developmental pigmentation", "d": ["The developmental process that results in the deposition of coloring matter in an organism, tissue or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019461", "l": "glutamine catabolic process to fumarate, using glutamate synthase (NADPH)", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with the conversion of glutamine to glutamate catalyzed by the enzyme glutamate synthase (NADPH) (EC:1.4.1.13)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070415", "l": "trehalose metabolism in response to cold stress", "d": ["The chemical reactions and pathways involving trehalose that occur as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.876036511014462", "identifiers": [{"i": "GO:0072697", "l": "protein localization to cell cortex", "d": ["A process in which a protein is transported to, or maintained in, the cell cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990068", "l": "seed dehydration", "d": ["The seed development process whose outcome is the drying of a maturing seed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045198", "l": "establishment of epithelial cell apical/basal polarity", "d": ["The specification and formation of the apicobasal polarity of an epithelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007038", "l": "endocytosed protein transport to vacuole", "d": ["The directed movement of proteins imported into a cell by endocytosis to the vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "48.065430609075051", "identifiers": [{"i": "GO:0009628", "l": "response to abiotic stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900127", "l": "positive regulation of hyaluronan biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904057", "l": "negative regulation of sensory perception of pain", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035910", "l": "ascending aorta morphogenesis", "d": ["The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990417", "l": "snoRNA release from pre-rRNA", "d": ["The release of snoRNA from pre-rRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070609", "l": "regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0009129", "l": "pyrimidine nucleoside monophosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002571", "l": "somatic diversification of T cell receptor genes by N region addition", "d": ["The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the T cell receptor gene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0045766", "l": "positive regulation of angiogenesis", "d": ["Any process that activates or increases angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036290", "l": "protein trans-autophosphorylation", "d": ["The phosphorylation by a protein of a residue on an identical protein. For example, phosphorylation by the other kinase within a homodimer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001988", "l": "positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of heart contraction as a result of the baroreceptor response to decreased blood pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007554", "l": "regulation of ecdysteroid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904187", "l": "regulation of transformation of host cell by virus", "d": ["Any process that modulates the frequency, rate or extent of transformation of host cell by virus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0016122", "l": "xanthophyll metabolic process", "d": ["The chemical reactions and pathways involving xanthophylls, oxygen-containing carotenoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0006638", "l": "neutral lipid metabolic process", "d": ["The chemical reactions and pathways involving neutral lipids, lipids only soluble in solvents of very low polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902154", "l": "positive regulation of response to DNA damage checkpoint signaling", "d": ["Any process that activates or increases the frequency, rate or extent of response to DNA damage checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000781", "l": "positive regulation of double-strand break repair", "d": ["Any process that activates or increases the frequency, rate or extent of double-strand break repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000648", "l": "positive regulation of stem cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of stem cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035963", "l": "cellular response to interleukin-13", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0019344", "l": "cysteine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900137", "l": "negative regulation of chemokine activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chemokine activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072044", "l": "collecting duct development", "d": ["The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032671", "l": "regulation of interleukin-27 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-27 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018059", "l": "N-terminal peptidyl-serine deamination", "d": ["The oxidative deamination of N-terminal peptidyl-serine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903704", "l": "negative regulation of siRNA processing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of siRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0014721", "l": "twitch skeletal muscle contraction", "d": ["A process in which force is generated within twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The twitch skeletal muscle responds to neurostimulations with a contraction followed by a relaxation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002233", "l": "leukocyte chemotaxis involved in immune response", "d": ["The movement of an immune cell in response to an external stimulus a part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110138", "l": "positive regulation of imaginal disc-derived leg joint morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009606", "l": "tropism", "d": ["The movement of an organism, or part of an organism, in response to an external source of stimulus, usually toward or away from it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901526", "l": "positive regulation of mitophagy", "d": ["Any process that activates or increases the frequency, rate or extent of mitophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018215", "l": "protein phosphopantetheinylation", "d": ["The modification of a protein amino acid by phosphopantetheinylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002194", "l": "hepatocyte cell migration", "d": ["The orderly movement of a hepatocyte during the development of the liver. Hepatocytes emerge from the hepatic epithelium, populating the septum transversum and lateral mesenchymal areas of the hepatic lobes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006524", "l": "alanine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alanine, 2-aminopropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905774", "l": "regulation of DNA helicase activity", "d": ["Any process that modulates the frequency, rate or extent of ATP-dependent DNA helicase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903168", "l": "positive regulation of pyrroline-5-carboxylate reductase activity", "d": ["Any process that activates or increases the frequency, rate or extent of pyrroline-5-carboxylate reductase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032665", "l": "regulation of interleukin-21 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-21 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0051100", "l": "negative regulation of binding", "d": ["Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003118", "l": "regulation of vasoconstriction by neuronal norepinephrine", "d": ["Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of norepinephrine released by nerve endings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902846", "l": "positive regulation of mitotic spindle elongation", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic spindle elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.207992593949683", "identifiers": [{"i": "GO:0008206", "l": "bile acid metabolic process", "d": ["The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902427", "l": "regulation of water channel activity", "d": ["Any process that modulates the frequency, rate or extent of water channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904149", "l": "regulation of microglial cell mediated cytotoxicity", "d": ["Any process that modulates the frequency, rate or extent of microglial cell mediated cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035944", "l": "perforin production", "d": ["The appearance of a perforin protein due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990523", "l": "bone regeneration", "d": ["The regrowth of bone following its loss or destruction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0052545", "l": "callose localization", "d": ["Any process in which callose is transported to, and/or maintained in, a specific location. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902333", "l": "nuclear DNA replication DNA ligation", "d": ["Any DNA ligation that is involved in nuclear cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001552", "l": "ovarian follicle atresia", "d": ["A periodic process in which immature ovarian follicles degenerate and are subsequently re-absorbed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019340", "l": "dibenzofuran catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990261", "l": "pre-mRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the unspliced pre-mRNA (pre-messenger RNA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072392", "l": "phenol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phenol, a compound that consists of a benzene ring with one attached hydroxyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1904956", "l": "regulation of midbrain dopaminergic neuron differentiation", "d": ["Any process that modulates the frequency, rate or extent of midbrain dopaminergic neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904364", "l": "positive regulation of calcitonin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of calcitonin secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061048", "l": "negative regulation of branching involved in lung morphogenesis", "d": ["Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099148", "l": "regulation of synaptic vesicle docking", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle docking."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070574", "l": "cadmium ion transmembrane transport", "d": ["A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009915", "l": "phloem sucrose loading", "d": ["The process of loading sucrose into the sieve tube or companion cell of the phloem for long distance transport from source to sink."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090339", "l": "negative regulation of formin-nucleated actin cable assembly", "d": ["Any process that decreases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140924", "l": "L-kynurenine transmembrane transport", "d": ["The directed movement of L-kynurenine across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010571", "l": "positive regulation of nuclear cell cycle DNA replication", "d": ["Any process that activates or increases the frequency, rate or extent of the DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0060384", "l": "innervation", "d": ["The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030389", "l": "fructosamine metabolic process", "d": ["The chemical reactions and pathways involving fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0031529", "l": "ruffle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003036", "l": "detection of pH by aortic body chemoreceptor signaling", "d": ["The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in an aortic body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902973", "l": "mitotic DNA replication DNA ligation", "d": ["Any DNA ligation involved in mitotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902801", "l": "regulation of siRNA-independent facultative heterochromatin formation", "d": ["Any process that modulates the frequency, rate or extent of siRNA-independent facultative heterochromatin assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009942", "l": "longitudinal axis specification", "d": ["The establishment, maintenance and elaboration of the longitudinal axis. In plants, this is the axis that runs from the shoot to the root."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.970323817434654", "identifiers": [{"i": "GO:0046649", "l": "lymphocyte activation", "d": ["A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903500", "l": "negative regulation of mitotic actomyosin contractile ring assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006614", "l": "SRP-dependent cotranslational protein targeting to membrane", "d": ["The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0018342", "l": "protein prenylation", "d": ["The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000553", "l": "positive regulation of T-helper 2 cell cytokine production", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 2 cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120194", "l": "regulation of anther dehiscence", "d": ["Any process involved in the dehiscence of an anther to release the pollen grains contained within it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903369", "l": "negative regulation of foraging behavior", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of foraging behavior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030588", "l": "pseudocleavage", "d": ["Partial constriction of the cytoplasm of a cell to form a furrow that resembles a cleavage furrow but does not complete cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0008055", "l": "ocellus pigment biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ocellus pigments, general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.232064878529073", "identifiers": [{"i": "GO:0072210", "l": "metanephric nephron development", "d": ["The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903952", "l": "regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization", "d": ["Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.426153789046865", "identifiers": [{"i": "GO:0031503", "l": "protein-containing complex localization", "d": ["A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0070232", "l": "regulation of T cell apoptotic process", "d": ["Any process that modulates the occurrence or rate of T cell death by apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021599", "l": "abducens nerve formation", "d": ["The process that gives rise to the abducens nerve. This process pertains to the initial formation of a structure from unspecified parts. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006565", "l": "L-serine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071764", "l": "nuclear outer membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0001762", "l": "beta-alanine transport", "d": ["The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097329", "l": "response to antimetabolite", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimetabolite stimulus. An antimetabolite is a substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140403", "l": "effector-mediated suppression of host innate immune response", "d": ["A process mediated by a molecule secreted by a symbiont that results in the suppression of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010693", "l": "negative regulation of alkaline phosphatase activity", "d": ["Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061384", "l": "heart trabecula morphogenesis", "d": ["The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0090090", "l": "negative regulation of canonical Wnt signaling pathway", "d": ["Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072724", "l": "response to 4-nitroquinoline N-oxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009209", "l": "pyrimidine ribonucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0052020", "l": "modification by symbiont of host cell wall", "d": ["The process in which an organism effects a change in the structure or function of the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150103", "l": "reactive gliosis", "d": ["A neuroinflammatory response, occurring over several days, during which glial cells undergo nonspecific reactive changes in response to damage to the central nervous system (CNS); typically involves the proliferation or hypertrophy of different types of glial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901248", "l": "positive regulation of lung ciliated cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071768", "l": "mycolic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0120055", "l": "small intestinal transit", "d": ["Migration of ingested material along the length of the small intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003052", "l": "circadian regulation of systemic arterial blood pressure", "d": ["Any process in which an organism modulates its blood pressure at different values with a regularity of approximately 24 hours."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031444", "l": "slow-twitch skeletal muscle fiber contraction", "d": ["A process in which force is generated within slow-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The slow-twitch skeletal muscle is characterized by slow time parameters, low force development and resistance to fatigue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061081", "l": "positive regulation of myeloid leukocyte cytokine production involved in immune response", "d": ["Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071289", "l": "cellular response to nickel ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0019477", "l": "L-lysine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903613", "l": "regulation of protein tyrosine phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of protein tyrosine phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0014824", "l": "artery smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the artery. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The artery is a vessel carrying blood away from the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045067", "l": "positive extrathymic T cell selection", "d": ["The process of sparing extrathymically maturing T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090152", "l": "establishment of protein localization to mitochondrial membrane involved in mitochondrial fission", "d": ["The directed movement of a protein to a specific location in the mitochondrial membrane that contributes to mitochondrial fission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903965", "l": "monounsaturated fatty acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of monounsaturated fatty acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000767", "l": "positive regulation of cytoplasmic translation", "d": ["Any process that activates or increases the frequency, rate or extent of cytoplasmic translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110081", "l": "negative regulation of placenta blood vessel development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904882", "l": "regulation of telomerase catalytic core complex assembly", "d": ["Any process that modulates the frequency, rate or extent of telomerase catalytic core complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0098814", "l": "spontaneous synaptic transmission", "d": ["The low level of synaptic transmission that occurs via spontaneous neurotransmitter release into the synaptic cleft in the absence of a presynaptic action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0071046", "l": "nuclear polyadenylation-dependent ncRNA catabolic process", "d": ["The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097490", "l": "sympathetic neuron projection extension", "d": ["Long distance growth of a single sympathetic neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0052546", "l": "cell wall pectin metabolic process", "d": ["The chemical reactions and pathways involving pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900657", "l": "positive regulation of diorcinol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of diorcinol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900716", "l": "regulation of violaceol II biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of violaceol II biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0039019", "l": "pronephric nephron development", "d": ["The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903853", "l": "regulation of stress response to copper ion", "d": ["Any process that modulates the frequency, rate or extent of stress response to copper ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0048024", "l": "regulation of mRNA splicing, via spliceosome", "d": ["Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0003179", "l": "heart valve morphogenesis", "d": ["The process in which the structure of a heart valve is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060785", "l": "regulation of apoptosis involved in tissue homeostasis", "d": ["Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009764", "l": "PEP carboxykinase C4 photosynthesis", "d": ["The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is phosphoenolpyruvate carboxykinase (PEPCK)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990437", "l": "snRNA 2'-O-methylation", "d": ["The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an snRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.961764377177126", "identifiers": [{"i": "GO:0050878", "l": "regulation of body fluid levels", "d": ["Any process that modulates the levels of body fluids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042845", "l": "glycol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903348", "l": "positive regulation of bicellular tight junction assembly", "d": ["Any process that activates or increases the frequency, rate or extent of tight junction assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032121", "l": "meiotic attachment of telomeric heterochromatin to spindle pole body", "d": ["The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the spindle pole body, facilitating bouquet formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009254", "l": "peptidoglycan turnover", "d": ["The continual breakdown and regeneration of peptidoglycan required to maintain the cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901230", "l": "negative regulation of non-canonical Wnt signaling pathway via JNK cascade", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.157169620444122", "identifiers": [{"i": "GO:0002703", "l": "regulation of leukocyte mediated immunity", "d": ["Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021601", "l": "abducens nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the abducens nerve to attain its fully functional state. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006703", "l": "estrogen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019270", "l": "aerobactin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0030244", "l": "cellulose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043158", "l": "heterocyst development", "d": ["The cellular developmental process by which a cell becomes a heterocyst, a cell that carries out nitrogen fixation. This process involves changes to the cell wall, expression of nitrogenase and other proteins involved in nitrogen fixation, and degradation of photosystem II, which produces oxygen. This process is known to occur in some cyanobacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902034", "l": "negative regulation of hematopoietic stem cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061867", "l": "establishment of mitotic spindle asymmetry", "d": ["The mitotic spindle organization process by which a mitotic spindle becomes asymmetric either in position or structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900978", "l": "negative regulation of tatiopterin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052489", "l": "negative regulation by host of symbiont programmed cell death", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904153", "l": "negative regulation of retrograde protein transport, ER to cytosol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0039595", "l": "induction by virus of catabolism of host mRNA", "d": ["The process in which a virus increases the frequency, rate or extent of the breakdown of host messenger RNA (mRNA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006788", "l": "heme oxidation", "d": ["The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in heme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0019336", "l": "phenol-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033029", "l": "regulation of neutrophil apoptotic process", "d": ["Any process that modulates the frequency, rate, or extent of neutrophil apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0060581", "l": "cell fate commitment involved in pattern specification", "d": ["The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000329", "l": "negative regulation of T-helper 17 cell lineage commitment", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell lineage commitment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0150179", "l": "positive regulation of phosphatidylserine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylserine metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0061101", "l": "neuroendocrine cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018401", "l": "peptidyl-proline hydroxylation to 4-hydroxy-L-proline", "d": ["The modification of peptidyl-proline to form 4-hydroxy-L-proline; catalyzed by procollagen-proline,2-oxoglutarate-4-dioxygenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051438", "l": "regulation of ubiquitin-protein transferase activity", "d": ["Any process that modulates the frequency, rate or extent of ubiquitin transferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000254", "l": "regulation of male germ cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of male germ cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035724", "l": "CD24 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CD24, a CD marker and cell adhesion molecule that occurs on many B-lineage cells and mature granulocytes, and is involved in B cell activation and differentiation as well as T cell co-stimulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905602", "l": "positive regulation of receptor-mediated endocytosis involved in cholesterol transport", "d": ["Any process that activates or increases the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1905047", "l": "mitotic spindle pole body organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitotic spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0061678", "l": "Entner-Doudoroff pathway", "d": ["A cellular carbohydrate catabolic process that converts a carbohydrate to pyruvate and either glyceraldehyde or glyceraldehyde-3 phosphate by dehydration and aldol cleavage via a gluconate or 6-phosphogluconate intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0046636", "l": "negative regulation of alpha-beta T cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033302", "l": "quercetin O-glucoside metabolic process", "d": ["The chemical reactions and pathways involving O-glucosylated derivatives of quercetin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032847", "l": "regulation of cellular pH reduction", "d": ["Any process that modulates the frequency, rate, or extent of a process that reduces the internal pH of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019543", "l": "propionate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of propionate, the anion derived from propionic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106213", "l": "kinetochore disassembly involved in meiotic chromosome organization", "d": ["The cell cycle process in which outer kinetochore components delocalize from the centromere, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0003387", "l": "neuron differentiation involved in amphid sensory organ development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron that contributes to the progression of the amphid sensory gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018980", "l": "2,4,5-trichlorophenoxyacetic acid metabolic process", "d": ["The chemical reactions and pathways involving 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound which is widely used as a herbicide, often as a weed killer for home lawns."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010183", "l": "pollen tube guidance", "d": ["The process in which the growth of pollen tube is directed towards the female gametophyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021699", "l": "cerebellar cortex maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051623", "l": "positive regulation of norepinephrine uptake", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061824", "l": "cytosolic ciliogenesis", "d": ["The process in which an axoneme is exposed entirely or partially to the cytoplasm or by which the cytoplasmic portion is assembled or extended. Cytosolic ciliogenesis can occur following compartmentalized ciliogenesis, in which the cilium is formed within a compartment separated from the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990211", "l": "positive regulation by symbiont of jasmonic acid levels in host", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of the jasmonic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0003357", "l": "noradrenergic neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900945", "l": "negative regulation of isoprene metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of isoprene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018011", "l": "N-terminal peptidyl-alanine methylation", "d": ["The methylation of the N-terminal alanine of proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046967", "l": "cytosol to endoplasmic reticulum transport", "d": ["The directed movement of substances from the cytosol to the endoplasmic reticulum of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032536", "l": "regulation of cell projection size", "d": ["A process that modulates the size of a cell projection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043504", "l": "mitochondrial DNA repair", "d": ["The process of restoring mitochondrial DNA after damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097676", "l": "histone H3-K36 dimethylation", "d": ["The modification of histone H3 by addition of two methyl groups to lysine at position 36 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000143", "l": "negative regulation of DNA-templated transcription initiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-templated transcription initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.685364931984026", "identifiers": [{"i": "GO:0016137", "l": "glycoside metabolic process", "d": ["The chemical reactions and pathways involving glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0034650", "l": "cortisol metabolic process", "d": ["The chemical reactions and pathways involving cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901038", "l": "cyanidin 3-O-glucoside metabolic process", "d": ["The chemical reactions and pathways involving cyanidin 3-O-beta-D-glucoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044082", "l": "modulation by symbiont of host small GTPase mediated signal transduction", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of small GTPase mediated signal transduction in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0018352", "l": "protein-pyridoxal-5-phosphate linkage", "d": ["The formation of a linkage between a protein amino acid and pyridoxal-5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034498", "l": "early endosome to Golgi transport", "d": ["The directed movement of substances from early endosomes to the Golgi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098755", "l": "maintenance of seed dormancy by absisic acid", "d": ["The process by which seed dormancy is maintained by the presence of absisic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060005", "l": "vestibular reflex", "d": ["A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902764", "l": "positive regulation of embryonic skeletal joint development", "d": ["Any process that activates or increases the frequency, rate or extent of embryonic skeletal joint development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075322", "l": "regulation of oomycete sporangium development", "d": ["Any process that modulates the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075030", "l": "modulation of formation of symbiont germ tube hook structure for appressorium development", "d": ["Any process that modulates the frequency, rate or extent of symbiont germ tube hook structure formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035726", "l": "common myeloid progenitor cell proliferation", "d": ["The multiplication or reproduction of common myeloid progenitor cells, resulting in the expansion of a cell population. A common myeloid progenitor cell is a progenitor cell committed to the myeloid lineage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0006817", "l": "phosphate ion transport", "d": ["The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905025", "l": "negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902865", "l": "positive regulation of embryonic camera-type eye development", "d": ["Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001241", "l": "positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "d": ["Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0031363", "l": "N-terminal protein amino acid deamination", "d": ["The removal of an amino group from the N-terminal amino acid residue of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001108", "l": "positive regulation of Rho guanyl-nucleotide exchange factor activity", "d": ["Any process that activates or increases the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0003278", "l": "apoptotic process involved in heart morphogenesis", "d": ["Any apoptotic process that contributes to the shaping of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042863", "l": "pyochelin metabolic process", "d": ["The chemical reactions and pathways involving the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120056", "l": "large intestinal transit", "d": ["Migration of ingested material along the length of the large intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090025", "l": "regulation of monocyte chemotaxis", "d": ["Any process that modulates the frequency, rate, or extent of monocyte chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006121", "l": "mitochondrial electron transport, succinate to ubiquinone", "d": ["The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905005", "l": "regulation of epithelial to mesenchymal transition involved in endocardial cushion formation", "d": ["Any process that modulates the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071354", "l": "cellular response to interleukin-6", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0097198", "l": "histone H3-K36 trimethylation", "d": ["The modification of histone H3 by addition of three methyl groups to lysine at position 36 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006101", "l": "citrate metabolic process", "d": ["The chemical reactions and pathways involving citrate, 2-hydroxy-1,2,3-propanetricarboyxlate. Citrate is widely distributed in nature and is an important intermediate in the TCA cycle and the glyoxylate cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0032305", "l": "positive regulation of icosanoid secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the controlled release of an icosanoid from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018971", "l": "anaerobic toluene metabolic process", "d": ["The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, that occur in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032713", "l": "negative regulation of interleukin-4 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034289", "l": "detection of maltose stimulus", "d": ["The series of events in which a maltose stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000812", "l": "regulation of barbed-end actin filament capping", "d": ["Any process that modulates the frequency, rate or extent of barbed-end actin filament capping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0072102", "l": "glomerulus morphogenesis", "d": ["The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.415093686714229", "identifiers": [{"i": "GO:0001821", "l": "histamine secretion", "d": ["The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902170", "l": "cellular response to reactive nitrogen species", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive nitrogen species stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045815", "l": "transcription initiation-coupled chromatin remodeling", "d": ["An epigenetic mechanism of regulation of gene expression that involves chromatin remodeling to capacitate gene expression by either modifying the chromatin fiber, the nucleosomal histones, or the DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106088", "l": "regulation of cell adhesion involved in sprouting angiogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140235", "l": "RNA polyadenylation at postsynapse", "d": ["A polyadenylation event (the enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule) that takes place at a postsynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048796", "l": "swim bladder maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a swim bladder to attain its fully functional state. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0042783", "l": "evasion of host immune response", "d": ["A process by which an organism avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0008315", "l": "G2/MI transition of meiotic cell cycle", "d": ["The cell cycle process in which a cell progresses from meiotic G2 phase to M phase of meiosis I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140570", "l": "extraction of mislocalized protein from mitochondrial outer membrane", "d": ["The removal of a mislocalized protein from the mitochondrial outer membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030922", "l": "peptidyl-tyrosine dehydrogenation to form (E)-2,3-didehydrotyrosine", "d": ["The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(E)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015709", "l": "thiosulfate transport", "d": ["The directed movement of thiosulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905910", "l": "negative regulation of dauer entry", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dauer entry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0051328", "l": "meiotic interphase", "d": ["The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035092", "l": "sperm DNA condensation", "d": ["The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0019290", "l": "siderophore biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051559", "l": "phlobaphene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048831", "l": "regulation of shoot system development", "d": ["Any process that modulates the frequency, rate or extent of shoot development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901469", "l": "regulation of syringal lignin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of syringal lignin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007477", "l": "notum development", "d": ["The process whose specific outcome is the progression of the dorsal part of the body over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071269", "l": "L-homocysteine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-homocysteine, the L-enantiomer of 2-amino-4-sulfanylbutanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071959", "l": "maintenance of mitotic sister chromatid cohesion, arms", "d": ["The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001093", "l": "galactotriose transport", "d": ["The directed movement of a galactotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904636", "l": "response to ionomycin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904095", "l": "negative regulation of endosperm development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endosperm development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021676", "l": "rhombomere 8 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 8. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030713", "l": "follicle cell of egg chamber stalk formation", "d": ["Development of ovarian follicle cells to create the interfollicular stalks that connect the egg chambers of progressive developmental stages. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002732", "l": "positive regulation of dendritic cell cytokine production", "d": ["Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0042490", "l": "mechanoreceptor differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0090673", "l": "endothelial cell-matrix adhesion", "d": ["The binding of an endothelial cell to the extracellular matrix via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0006195", "l": "purine nucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0015996", "l": "chlorophyll catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, into less complex products."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003350", "l": "pulmonary myocardium development", "d": ["The progression of the pulmonary myocardium over time, from its initial formation to the mature structure. The pulmonary myocardium is the myocardial tissue present in the pulmonary vein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160057", "l": "plant endodermal cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a plant endodermal cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007557", "l": "regulation of juvenile hormone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0032951", "l": "regulation of beta-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of beta-glucans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009754", "l": "detection of jasmonic acid stimulus", "d": ["The series of events in which a jasmonic acid stimulus is received by a cell and converted into a molecular signal. Series of events required for a jasmonic acid stimulus to be detected and converted to a signal molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031495", "l": "negative regulation of mating type switching", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0050860", "l": "negative regulation of T cell receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1904359", "l": "regulation of spore germination", "d": ["Any process that modulates the frequency, rate or extent of spore germination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075521", "l": "microtubule-dependent intracellular transport of viral material towards nucleus", "d": ["The directed movement of a virus, or part of a virus, towards the host cell nucleus using host microtubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901783", "l": "p-cumate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of p-cumate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045928", "l": "negative regulation of juvenile hormone metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032654", "l": "regulation of interleukin-11 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-11 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0016077", "l": "sno(s)RNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0044743", "l": "protein transmembrane import into intracellular organelle", "d": ["The directed movement of proteins into an intracellular organelle, across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0050884", "l": "neuromuscular process controlling posture", "d": ["Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900876", "l": "nonadec-1-ene metabolic process", "d": ["The chemical reactions and pathways involving nonadec-1-ene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.651716354923636", "identifiers": [{"i": "GO:0060541", "l": "respiratory system development", "d": ["The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046272", "l": "stilbene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0055118", "l": "negative regulation of cardiac muscle contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070376", "l": "regulation of ERK5 cascade", "d": ["Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK5 cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030070", "l": "insulin processing", "d": ["The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032974", "l": "amino acid transmembrane export from vacuole", "d": ["The directed movement of amino acids out of the vacuole, across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061058", "l": "regulation of peptidoglycan recognition protein signaling pathway", "d": ["Any process that modulates the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150145", "l": "positive regulation of CD80 production", "d": ["Any process that activates or increases the frequency, rate or extent of CD80 biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046050", "l": "UMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of UMP, uridine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042128", "l": "nitrate assimilation", "d": ["The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900589", "l": "violaceol I catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of violaceol I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0008616", "l": "queuosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of queuosines, a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003406", "l": "retinal pigment epithelium development", "d": ["The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051677", "l": "pullulan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0032204", "l": "regulation of telomere maintenance", "d": ["Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006335", "l": "DNA replication-dependent chromatin assembly", "d": ["The formation of nucleosomes on newly synthesized DNA, coupled to strand elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904147", "l": "response to nonylphenol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021728", "l": "inferior reticular formation development", "d": ["The process whose specific outcome is the progression of the inferior reticular formation over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048336", "l": "positive regulation of mesodermal cell fate determination", "d": ["Any process that activates or increases the frequency, rate or extent of mesoderm cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902615", "l": "immune response involved in response to exogenous dsRNA", "d": ["Any immune response that is involved in response to exogenous dsRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048331", "l": "axial mesoderm structural organization", "d": ["The process that contributes to the act of creating the structural organization of the axial mesoderm. This process pertains to the physical shaping of a rudimentary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000423", "l": "negative regulation of eosinophil chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000419", "l": "regulation of eosinophil extravasation", "d": ["Any process that modulates the frequency, rate or extent of eosinophil extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0051926", "l": "negative regulation of calcium ion transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001954", "l": "positive regulation of cell-matrix adhesion", "d": ["Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000970", "l": "regulation of detection of glucose", "d": ["Any process that modulates the frequency, rate or extent of detection of glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046595", "l": "establishment of pole plasm mRNA localization", "d": ["Any process that results in the directed movement of mRNA to the oocyte pole plasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904204", "l": "regulation of skeletal muscle hypertrophy", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900600", "l": "endocrocin metabolic process", "d": ["The chemical reactions and pathways involving endocrocin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019872", "l": "streptomycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of streptomycin, a commonly used antibiotic in cell culture media; it acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0006208", "l": "pyrimidine nucleobase catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:2000677", "l": "regulation of transcription regulatory region DNA binding", "d": ["Any process that modulates the frequency, rate or extent of transcription regulatory region DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900183", "l": "regulation of xanthone-containing compound biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of xanthone-containing compound biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904340", "l": "positive regulation of dopaminergic neuron differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "47.949658210835416", "identifiers": [{"i": "GO:0043412", "l": "macromolecule modification", "d": ["The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902238", "l": "regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator", "d": ["Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.651613913496419", "identifiers": [{"i": "GO:1990542", "l": "mitochondrial transmembrane transport", "d": ["The process in which a solute is transported from one side of a membrane to the other into, out of or within a mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901193", "l": "regulation of formation of translation preinitiation complex", "d": ["Any process that modulates the frequency, rate or extent of formation of translation preinitiation complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045853", "l": "negative regulation of bicoid mRNA localization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002760", "l": "positive regulation of antimicrobial humoral response", "d": ["Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045008", "l": "depyrimidination", "d": ["The disruption of the bond between the sugar in the backbone and the C or T base, causing the base to be removed and leaving a depyrimidinated sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905381", "l": "negative regulation of snRNA transcription by RNA polymerase II", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048245", "l": "eosinophil chemotaxis", "d": ["The movement of an eosinophil in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019092", "l": "mitochondrial srRNA export from mitochondrion", "d": ["The process in which a srRNA, small subunit ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097491", "l": "sympathetic neuron projection guidance", "d": ["The process in which the migration of a sympathetic neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075184", "l": "regulation of infection cushion formation", "d": ["Any process that modulates the frequency, rate or extent of symbiont infection cushion formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033353", "l": "S-adenosylmethionine cycle", "d": ["A cyclic series of interconversions involving S-adenosylmethionine, S-adenosyl-L-homocysteine, L-cysteine, and L-methionine. Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of methionine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904477", "l": "positive regulation of small GTPase binding", "d": ["Any process that activates or increases the frequency, rate or extent of small GTPase binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904151", "l": "positive regulation of microglial cell mediated cytotoxicity", "d": ["Any process that activates or increases the frequency, rate or extent of microglial cell mediated cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:1901532", "l": "regulation of hematopoietic progenitor cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0001833", "l": "inner cell mass cell proliferation", "d": ["The proliferation of cells in the inner cell mass."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120139", "l": "positive regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002806", "l": "negative regulation of antimicrobial peptide biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009144", "l": "purine nucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002158", "l": "osteoclast proliferation", "d": ["The multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901801", "l": "1,5-anhydro-D-fructose metabolic process", "d": ["The chemical reactions and pathways involving 1,5-anhydro-D-fructose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043454", "l": "alkyne catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.654352968788714", "identifiers": [{"i": "GO:0003015", "l": "heart process", "d": ["A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0007350", "l": "blastoderm segmentation", "d": ["The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904562", "l": "phosphatidylinositol 5-phosphate metabolic process", "d": ["The chemical reactions and pathways involving phosphatidylinositol 5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048072", "l": "compound eye pigmentation", "d": ["Establishment of a pattern of pigment in the compound eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.660382697154006", "identifiers": [{"i": "GO:0019538", "l": "protein metabolic process", "d": ["The chemical reactions and pathways involving a protein. Includes protein modification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010478", "l": "chlororespiration", "d": ["A respiratory electron flow (from NAD(P)H to plastoquinone (PQ) and O2) involving both a nonphotochemical reduction and re-oxidation of PQ pool."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0002837", "l": "regulation of immune response to tumor cell", "d": ["Any process that modulates the frequency, rate, or extent of an immune response to tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0009642", "l": "response to light intensity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0048521", "l": "negative regulation of behavior", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097753", "l": "membrane bending", "d": ["A membrane organization process resulting in the bending of a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046895", "l": "N-terminal peptidyl-isoleucine methylation", "d": ["The methylation of the N-terminal isoleucine of proteins to form the derivative N-methyl-L-isoleucine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007087", "l": "mitotic nuclear pore complex reassembly", "d": ["The cell cycle process in which nuclear pore complexes reform during mitotic cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904420", "l": "positive regulation of telomeric loop formation", "d": ["Any process that activates or increases the frequency, rate or extent of telomeric loop formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.362525179576039", "identifiers": [{"i": "GO:0022611", "l": "dormancy process", "d": ["A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030513", "l": "positive regulation of BMP signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003315", "l": "heart rudiment formation", "d": ["The developmental process pertaining to the initial formation of the heart rudiment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0033696", "l": "heterochromatin boundary formation", "d": ["A process that forms a boundary that limits the spreading of heterochromatin along a chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009603", "l": "detection of symbiotic fungus", "d": ["The series of events in which a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism, is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006685", "l": "sphingomyelin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000606", "l": "regulation of cell proliferation involved in mesonephros development", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010706", "l": "ganglioside biosynthetic process via lactosylceramide", "d": ["The chemical reactions and pathways resulting in the formation of gangliosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.465174152298118", "identifiers": [{"i": "GO:0000959", "l": "mitochondrial RNA metabolic process", "d": ["The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042812", "l": "pheromone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0060920", "l": "cardiac pacemaker cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060921", "l": "sinoatrial node cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006659", "l": "phosphatidylserine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902259", "l": "regulation of delayed rectifier potassium channel activity", "d": ["Any process that modulates the frequency, rate or extent of delayed rectifier potassium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0016545", "l": "male courtship behavior, veined wing vibration", "d": ["The process during courtship where the male insect vibrates his wings. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061121", "l": "regulation of positive chemotaxis to cAMP by DIF-2", "d": ["Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090508", "l": "phenylethylamine biosynthetic process involved in synaptic transmission", "d": ["The chemical reactions and pathways resulting in the formation of phenylethylamine that contribute to synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046468", "l": "phosphatidyl-N-monomethylethanolamine metabolic process", "d": ["The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group. Present in trace levels in plants and slightly higher in bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010050", "l": "vegetative phase change", "d": ["Any process involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002272", "l": "plasmacytoid dendritic cell differentiation involved in immune response", "d": ["The process in which an immature plasmacytoid dendritic cell acquires the specialized features of a mature plasmacytoid dendritic cell contributing to an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051564", "l": "positive regulation of smooth endoplasmic reticulum calcium ion concentration", "d": ["Any process that increases the concentration of calcium ions in the smooth endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010105", "l": "negative regulation of ethylene-activated signaling pathway", "d": ["Any process that stops or prevents ethylene (ethene) signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002905", "l": "regulation of mature B cell apoptotic process", "d": ["Any process that modulates the frequency, rate, or extent of mature B cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036148", "l": "phosphatidylglycerol acyl-chain remodeling", "d": ["Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation reactions, to generate phosphatidylglycerol containing different types of fatty acid acyl chains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0050667", "l": "homocysteine metabolic process", "d": ["The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important intermediate in the metabolic reactions of its S-methyl derivative, methionine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018269", "l": "GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0006722", "l": "triterpenoid metabolic process", "d": ["The chemical reactions and pathways involving triterpenoid compounds, terpenoids with six isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905117", "l": "regulation of ribonucleoside-diphosphate reductase activity", "d": ["Any process that modulates the frequency, rate or extent of ribonucleoside-diphosphate reductase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006501", "l": "C-terminal protein lipidation", "d": ["The covalent attachment of a lipid group to the carboxy-terminus of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0014010", "l": "Schwann cell proliferation", "d": ["The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033567", "l": "DNA replication, Okazaki fragment processing", "d": ["The DNA metabolic process, occurring during lagging strand synthesis, by which RNA primers are removed from Okazaki fragments, the resulting gaps filled by DNA polymerization, and the ends ligated to form a continuous strand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901155", "l": "paromomycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of paromomycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072190", "l": "ureter urothelium development", "d": ["The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036069", "l": "light-dependent bacteriochlorophyll biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the presence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905377", "l": "response to D-galactose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072736", "l": "cellular response to tert-butyl hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015953", "l": "pyrimidine nucleotide interconversion", "d": ["The chemical reactions and pathways by which a pyrimidine nucleotide is synthesized from another pyrimidine nucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043552", "l": "positive regulation of phosphatidylinositol 3-kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900366", "l": "negative regulation of defense response to insect", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0016099", "l": "monoterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monoterpenoid compounds, terpenoids having a C10 skeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0042706", "l": "eye photoreceptor cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into an eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0001788", "l": "antibody-dependent cellular cytotoxicity", "d": ["Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150079", "l": "negative regulation of neuroinflammatory response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009252", "l": "peptidoglycan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905041", "l": "regulation of epithelium regeneration", "d": ["Any process that modulates the frequency, rate or extent of epithelium regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904145", "l": "negative regulation of meiotic cell cycle process involved in oocyte maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072449", "l": "response to G1 cell size control checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of mitotic cell cycle G1/S transition size control checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000917", "l": "positive regulation of glucuronoxylan catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of glucuronoxylan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0015865", "l": "purine nucleotide transport", "d": ["The directed movement of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, into, out of or within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.128151444246335", "identifiers": [{"i": "GO:0051173", "l": "positive regulation of nitrogen compound metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902015", "l": "poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolic process", "d": ["The chemical reactions and pathways involving poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071481", "l": "cellular response to X-ray", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048715", "l": "negative regulation of oligodendrocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902782", "l": "response to decane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001231", "l": "regulation of protein localization to prospore membrane", "d": ["Any process that modulates the frequency, rate or extent of protein localization to prospore membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048344", "l": "paraxial mesodermal cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1901863", "l": "positive regulation of muscle tissue development", "d": ["Any process that activates or increases the frequency, rate or extent of muscle tissue development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000480", "l": "negative regulation of cAMP-dependent protein kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000604", "l": "negative regulation of secondary growth", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of secondary growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070978", "l": "voltage-gated calcium channel complex assembly", "d": ["Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007057", "l": "spindle assembly involved in female meiosis I", "d": ["The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis I of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905647", "l": "proline import across plasma membrane", "d": ["The directed movement of proline from outside of a cell into the cytoplasmic compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060673", "l": "cell-cell signaling involved in placenta development", "d": ["Any process that mediates the transfer of information from one cell to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0014820", "l": "tonic smooth muscle contraction", "d": ["A process in which force is generated within tonic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the tonic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Tonic smooth muscle contraction occurs as a sustained continuous contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0050869", "l": "negative regulation of B cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904778", "l": "positive regulation of protein localization to cell cortex", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021992", "l": "cell proliferation involved in neural plate elongation", "d": ["The process of expansion of cell numbers in the neural plate due to cell division of progenitor cells preferentially in the rostrocaudal direction, resulting in the elongation of the tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090165", "l": "regulation of secretion by asymmetric Golgi ribbon formation", "d": ["The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that modulates the controlled release of a substance from a polarized epithelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001303", "l": "lipoxin A4 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900131", "l": "negative regulation of lipid binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140236", "l": "translation at presynapse", "d": ["Translation that occurs at the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0006971", "l": "hypotonic response", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0086064", "l": "cell communication by electrical coupling involved in cardiac conduction", "d": ["The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels and contributes to the process of cardiac conduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0050771", "l": "negative regulation of axonogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901805", "l": "beta-glucoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of beta-glucoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0080184", "l": "response to phenylpropanoid", "d": ["Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a phenylpropanoid stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. A phenylpropanoid is any of secondary metabolites with structures based on a phenylpropane skeleton. The class includes phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules. Phenylpropanoids are also precursors of lignin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0019827", "l": "stem cell population maintenance", "d": ["The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090347", "l": "regulation of cellular organohalogen metabolic process", "d": ["Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0030221", "l": "basophil differentiation", "d": ["The process in which a relatively unspecialized myeloid precursor cell acquires specialized features of a basophil cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019654", "l": "acetate fermentation", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of acetate, yielding energy in the form of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030961", "l": "peptidyl-arginine hydroxylation", "d": ["The hydroxylation of peptidyl-arginine to form peptidyl-hydroxyarginine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045942", "l": "negative regulation of phosphorus utilization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of phosphorus utilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0106295", "l": "resolvin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of resolvins, di- or trihydroxy fatty acids derived from omega-3 polyunsaturated fatty acids, specifically icosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0031339", "l": "negative regulation of vesicle fusion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900461", "l": "positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter", "d": ["Any process that activates or increases the frequency, rate or extent of pseudohyphal growth by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.780700721499244", "identifiers": [{"i": "GO:0022612", "l": "gland morphogenesis", "d": ["The process in which the anatomical structures of a gland are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032666", "l": "regulation of interleukin-22 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-22 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048790", "l": "maintenance of presynaptic active zone structure", "d": ["A process which maintains the organization and the arrangement of proteins at the active zone to ensure the fusion and docking of vesicles and the release of neurotransmitters."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900054", "l": "positive regulation of retinoic acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of retinoic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904991", "l": "negative regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009180", "l": "purine ribonucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045464", "l": "R8 cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an R8 cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046432", "l": "2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolic process", "d": ["The chemical reactions and pathways involving 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018062", "l": "peptidyl-tryptophan succinylation", "d": ["The modification of an N-terminal peptidyl-tryptophan residue to form peptidyl-N2-succinyl-L-tryptophan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902993", "l": "positive regulation of amyloid precursor protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of amyloid precursor protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900162", "l": "negative regulation of phospholipid scramblase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid scramblase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900439", "l": "positive regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus", "d": ["Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.314728742240533", "identifiers": [{"i": "GO:0043069", "l": "negative regulation of programmed cell death", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2001017", "l": "regulation of retrograde axon cargo transport", "d": ["Any process that modulates the frequency, rate or extent of retrograde axon cargo transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046094", "l": "deoxyinosine metabolic process", "d": ["The chemical reactions and pathways involving deoxyinosine, hypoxanthine deoxyriboside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002804", "l": "positive regulation of antifungal peptide production", "d": ["Any process that activates or increases the frequency, rate, or extent of antifungal peptide production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0010389", "l": "regulation of G2/M transition of mitotic cell cycle", "d": ["Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0003170", "l": "heart valve development", "d": ["The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0006776", "l": "vitamin A metabolic process", "d": ["The chemical reactions and pathways involving any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid, all of which are derivatives of beta-carotene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001896", "l": "autolysis", "d": ["A programmed cell death process observed in bacteria and filamentous fungi and leading to spontaneous death by lysis. Examples are lysis of the mother cell during sporulation of Bacillus subtilis and self-degradation of fungal cells in Aspergillus nidulans. Autolysis is also involved in bacterial biofilm formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042968", "l": "homoserine transport", "d": ["The directed movement of homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0060811", "l": "intracellular mRNA localization involved in anterior/posterior axis specification", "d": ["Any process in which mRNA is transported to, or maintained in, a specific location within the oocyte and/or syncytial embryo that contributes to the specification of the anterior/posterior axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904203", "l": "positive regulation of iodide transport", "d": ["Any process that activates or increases the frequency, rate or extent of iodide transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070455", "l": "positive regulation of heme biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.888270688603868", "identifiers": [{"i": "GO:0019318", "l": "hexose metabolic process", "d": ["The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:2000108", "l": "positive regulation of leukocyte apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0043396", "l": "corticotropin-releasing hormone secretion", "d": ["The regulated release of corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. CRH is produced by the hypothalamus and stimulates corticotropic cells of the anterior lobe of the pituitary to produce corticotropic hormone (CTH) and other biologically active substances e.g. 2-endorphin, release of CRH is affected by serum levels of cortisol, by stress and by the sleep/wake cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0009685", "l": "gibberellin metabolic process", "d": ["The chemical reactions and pathways involving gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000490", "l": "negative regulation of hepatic stellate cell activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900229", "l": "negative regulation of single-species biofilm formation in or on host organism", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation in or on host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001731", "l": "formation of translation preinitiation complex", "d": ["The joining of the small ribosomal subunit, ternary complex, and mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.938643630768524", "identifiers": [{"i": "GO:0010558", "l": "negative regulation of macromolecule biosynthetic process", "d": ["Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014815", "l": "initiation of skeletal muscle satellite cell activation by growth factor signaling, involved in skeletal muscle regeneration", "d": ["Signalling between growth factors and their receptors that results in the activation of satellite cell, where this process is involved in skeletal muscle regeneration. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060992", "l": "response to fungicide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061728", "l": "GDP-mannose biosynthetic process from mannose", "d": ["The chemical reactions and pathways resulting in the formation of GDP-mannose from mannose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016255", "l": "attachment of GPI anchor to protein", "d": ["A transamidation reaction that results in the cleavage of the polypeptide chain and the concomitant transfer of the GPI anchor to the newly formed carboxy-terminal amino acid of the anchored protein. The cleaved C-terminal contains the C-terminal GPI signal sequence of the newly synthesized polypeptide chain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070432", "l": "regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0043297", "l": "apical junction assembly", "d": ["The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002018", "l": "renin-angiotensin regulation of aldosterone production", "d": ["The process in which an increase in active angiotensin stimulates the adrenal cortices to secrete aldosterone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0033214", "l": "siderophore-dependent iron import into cell", "d": ["A process in which iron (Fe3+) is solubilized by ferric iron-specific chelators, known as siderophores, excreted by a cell; the iron-siderophore complex is then transported into the cell by specific cell surface receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903366", "l": "negative regulation of fear response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fear response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905829", "l": "negative regulation of prostaglandin catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:1901663", "l": "quinone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of quinone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0021695", "l": "cerebellar cortex development", "d": ["The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120183", "l": "positive regulation of focal adhesion disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061073", "l": "ciliary body morphogenesis", "d": ["The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0050915", "l": "sensory perception of sour taste", "d": ["The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045618", "l": "positive regulation of keratinocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018906", "l": "methyl tert-butyl ether metabolic process", "d": ["The chemical reactions and pathways involving methyl tert-butyl ether, 2-methoxy-2-methylpropane. Methyl tert-butyl ether is a synthetic chemical which is mixed with gasoline for use in reformulated gasoline. It was first introduced as an additive for unleaded gasoline in the 1980s. It is also used as a laboratory reagent and a pharmaceutical agent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052864", "l": "1-deoxy-D-xylulose 5-phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990786", "l": "cellular response to dsDNA", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000792", "l": "positive regulation of mesenchymal cell proliferation involved in lung development", "d": ["Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052575", "l": "carbohydrate localization", "d": ["Any process in which a carbohydrate is transported to, or maintained in, a specific location. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0098653", "l": "centromere clustering", "d": ["The process by which centromeres/kinetochores become localized to clusters."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003134", "l": "endodermal-mesodermal cell signaling involved in heart induction", "d": ["Any process that mediates the transfer of information from endodermal cells to mesodermal cells that contributes to heart induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035349", "l": "coenzyme A transmembrane transport", "d": ["The process in which coenzyme A is transported across a membrane. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032695", "l": "negative regulation of interleukin-12 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001575", "l": "globoside metabolic process", "d": ["The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070453", "l": "regulation of heme biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007023", "l": "post-chaperonin tubulin folding pathway", "d": ["Completion of folding of alpha- and beta-tubulin; takes place subsequent to chaperonin-mediated partial folding; mediated by a complex of folding cofactors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.019725967809748", "identifiers": [{"i": "GO:0016032", "l": "viral process", "d": ["A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0032635", "l": "interleukin-6 production", "d": ["The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016182", "l": "synaptic vesicle budding from endosome", "d": ["Budding of synaptic vesicles during the formation of constitutive recycling vesicles from early endosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905535", "l": "regulation of eukaryotic translation initiation factor 4F complex assembly", "d": ["Any process that modulates the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048022", "l": "negative regulation of melanin biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090463", "l": "intracellular lysine homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of lysine within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044405", "l": "detection of host", "d": ["The set of specific processes that allow an organism to detect the presence of its host via physical or chemical signals. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060641", "l": "mammary gland duct regression in males", "d": ["The process in which the epithelium of the mammary duct is destroyed in males."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120308", "l": "axonemal outer doublet assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an axonemal outer doublet, a part of an axoneme consisting of a doublet microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042618", "l": "poly-hydroxybutyrate metabolic process", "d": ["The chemical reactions and pathways involving poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032653", "l": "regulation of interleukin-10 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-10 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0002911", "l": "regulation of lymphocyte anergy", "d": ["Any process that modulates the frequency, rate, or extent of lymphocyte anergy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0032955", "l": "regulation of division septum assembly", "d": ["Any process that modulates the frequency, rate or extent of division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0048488", "l": "synaptic vesicle endocytosis", "d": ["A vesicle-mediated transport process, in which the synaptic vesicle membrane constituents are retrieved from the presynaptic membrane on the axon terminal after neurotransmitter secretion by exocytosis. Synaptic vesicle endocytosis can occur via clathrin-dependent and clathrin-independent mechanisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009125", "l": "nucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0097094", "l": "craniofacial suture morphogenesis", "d": ["The process in which any suture between cranial and/or facial bones is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048357", "l": "pedicel mucilage biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mucilage that occur in the flower stem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.388251399821804", "identifiers": [{"i": "GO:0008015", "l": "blood circulation", "d": ["The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990858", "l": "cellular response to lectin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0015945", "l": "methanol metabolic process", "d": ["The chemical reactions and pathways involving methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034421", "l": "post-translational protein acetylation", "d": ["The addition of an acetyl group to one or more amino acids in a protein, occurring after the protein has been completely translated and released from the ribosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043922", "l": "negative regulation by host of viral transcription", "d": ["Any process in which a host organism stops, prevents, or reduces the frequency, rate or extent of viral transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905156", "l": "negative regulation of photosynthesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of photosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051958", "l": "methotrexate transport", "d": ["The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002148", "l": "hypochlorous acid metabolic process", "d": ["The chemical reactions and pathways involving hypochlorous acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900638", "l": "negative regulation of asperfuranone biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of asperfuranone biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160001", "l": "extrasynaptic signaling via GABA", "d": ["Cell-cell signaling that starts with the activation of extrasynaptic GABA receptors in neurons through binding of ambient gamma-aminobutyric acid present in the extracellular fluid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.426153789046865", "identifiers": [{"i": "GO:0140353", "l": "lipid export from cell", "d": ["The directed movement of a lipid from a cell, into the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018172", "l": "peptidyl-L-3',4',5'-trihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine", "d": ["The modification of protein tyrosine to peptidyl-L-3',4',5'-dihydroxyphenylalanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0018948", "l": "xylene metabolic process", "d": ["The chemical reactions and pathways involving xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:1901994", "l": "negative regulation of meiotic cell cycle phase transition", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle phase transition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051591", "l": "response to cAMP", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021960", "l": "anterior commissure morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0009262", "l": "deoxyribonucleotide metabolic process", "d": ["The chemical reactions and pathways involving a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001543", "l": "ovarian follicle rupture", "d": ["Disruption of theca cell layer releasing follicular fluid and/or the oocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900663", "l": "positive regulation of emericellamide A biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of emericellamide A biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001292", "l": "codeine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050652", "l": "dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process", "d": ["The elongation of dermatan sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of dermatan sulfate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010815", "l": "bradykinin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the peptide bradykinin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0014029", "l": "neural crest formation", "d": ["The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0019079", "l": "viral genome replication", "d": ["Any process involved directly in viral genome replication, including viral nucleotide metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990953", "l": "intramanchette transport", "d": ["The movement of vesicles and protein complexes carried out by molecular motors, kinesins and dynein, along the microtubule tracks within the manchette and by myosin along actin filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003178", "l": "coronary sinus valve development", "d": ["The progression of the valve of the coronary sinus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048327", "l": "axial mesodermal cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010103", "l": "stomatal complex morphogenesis", "d": ["The process in which the anatomical structures of the stomatal complex are generated and organized. The stomatal complex is the stomatal guard cells and their associated epidermal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0090685", "l": "RNA localization to nucleus", "d": ["A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009155", "l": "purine deoxyribonucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070842", "l": "aggresome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an aggresome; requires the microtubule cytoskeleton and dynein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070963", "l": "positive regulation of neutrophil mediated killing of gram-negative bacterium", "d": ["Any process that increases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.644186068201407", "identifiers": [{"i": "GO:0042594", "l": "response to starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050859", "l": "negative regulation of B cell receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018879", "l": "biphenyl metabolic process", "d": ["The chemical reactions and pathways involving biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060240", "l": "negative regulation of signal transduction involved in conjugation with cellular fusion", "d": ["Any process that decreases the rate, frequency or extent of the series signal transduction involved in conjugation with cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902766", "l": "skeletal muscle satellite cell migration", "d": ["The orderly movement of a skeletal muscle satellite cell from one site to another. Migration of these cells is a key step in the process of growth and repair of skeletal muscle cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021598", "l": "abducens nerve morphogenesis", "d": ["The process in which the anatomical structure of the abducens nerve is generated and organized. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070760", "l": "positive regulation of interleukin-35-mediated signaling pathway", "d": ["Any process that increases the rate, frequency or extent of an interleukin-35-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0010165", "l": "response to X-ray", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044269", "l": "glycerol ether catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0030833", "l": "regulation of actin filament polymerization", "d": ["Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051069", "l": "galactomannan metabolic process", "d": ["The chemical reactions and pathways involving galactomannan, a polysaccharide composed of D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-galactose as single side units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035388", "l": "positive regulation of Roundabout signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the Roundabout signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0009409", "l": "response to cold", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990223", "l": "positive regulation by symbiont of cytokinin levels in host", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of the cytokinin levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904118", "l": "regulation of otic vesicle morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0001172", "l": "RNA-templated transcription", "d": ["The synthesis of an RNA transcript from an RNA template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009677", "l": "double fertilization forming two zygotes", "d": ["Rudimentary double fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the ventral canal cell nucleus to form a second zygote, which soon degenerates. An example of this process is found in the Gnetophytes, such as Welwitschia mirabilis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0043433", "l": "negative regulation of DNA-binding transcription factor activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0000090", "l": "mitotic anaphase", "d": ["The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901025", "l": "ripoptosome assembly involved in extrinsic apoptotic signaling pathway", "d": ["The aggregation, arrangement and bonding together of ripoptosome components leading to apoptosis via the extrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904789", "l": "regulation of mitotic actomyosin contractile ring maintenance", "d": ["Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring maintenance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900328", "l": "negative regulation of mannotriose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mannotriose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003436", "l": "regulation of cell adhesion involved in growth plate cartilage morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix and contributes to the shaping of the growth plate cartilage of an endochondral bone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043950", "l": "positive regulation of cAMP-mediated signaling", "d": ["Any process which activates, maintains or increases the frequency, rate or extent of cAMP-mediated signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044817", "l": "hydrogen generation via biophotolysis", "d": ["The production of hydrogen which results from the dissociation by light of water into molecular hydrogen and oxygen. This process is observed in cyanobacteria and microalgae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904979", "l": "negative regulation of endosome organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endosome organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035918", "l": "negative regulation of voltage-gated calcium channel activity in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated calcium channel in another organism. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021949", "l": "brainstem precerebellar neuron precursor migration", "d": ["The early migration of a precerebellar neuronal precursor in which a cell move from the rhombic lip, orthogonal to the direction of radial migration and ultimately reside in the brainstem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019423", "l": "sulfur oxidation, ferric ion-dependent", "d": ["A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur:ferric ion oxidoreductase, and requires the presence of ferric ion (Fe3+)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904464", "l": "regulation of matrix metallopeptidase secretion", "d": ["Any process that modulates the frequency, rate or extent of matrix metallopeptidase secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0031034", "l": "myosin filament assembly", "d": ["The aggregation, arrangement and bonding together of a filament composed of myosin molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060742", "l": "epithelial cell differentiation involved in prostate gland development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106015", "l": "negative regulation of inflammatory response to wounding", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.684842734364032", "identifiers": [{"i": "GO:0051938", "l": "L-glutamate import", "d": ["The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0061709", "l": "reticulophagy", "d": ["The selective autohagy process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033685", "l": "negative regulation of luteinizing hormone secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035814", "l": "negative regulation of renal sodium excretion", "d": ["Any process that decreases the amount of sodium excreted in urine over a unit of time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033574", "l": "response to testosterone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036322", "l": "pancreatic polypeptide secretion", "d": ["The regulated release of pancreatic polypeptide (PP) from a cell. Pancreatic polypeptide is a 36 amino acid polypeptide secreted by islets of Langerhans cells in the pancreas."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045832", "l": "positive regulation of light-activated channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of light-activated channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061386", "l": "closure of optic fissure", "d": ["The closure of the temporary ventral gap in the optic cup that contributes to its shaping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001194", "l": "regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine", "d": ["Any process that modulates the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0032367", "l": "intracellular cholesterol transport", "d": ["The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0034405", "l": "response to fluid shear stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120271", "l": "negative regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019601", "l": "toluene oxidation via 2-hydroxytoluene", "d": ["The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 2-hydroxytoluene (o-cresol)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052574", "l": "UDP-galactose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0032098", "l": "regulation of appetite", "d": ["Any process which modulates appetite, the desire or physical craving for food."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.586422797268227", "identifiers": [{"i": "GO:0033045", "l": "regulation of sister chromatid segregation", "d": ["Any process that modulates the frequency, rate or extent of sister chromatid segregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0051232", "l": "meiotic spindle elongation", "d": ["The lengthening of the distance between poles of the spindle during a meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031053", "l": "primary miRNA processing", "d": ["A process involved in the conversion of a primary microRNA transcript into a pre-microRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0045924", "l": "regulation of female receptivity", "d": ["Any process that modulates the frequency, rate or extent of the willingness or readiness of a female to receive male advances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0031124", "l": "mRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of an mRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001127", "l": "methane biosynthetic process from formic acid", "d": ["The chemical reactions and pathways resulting in the formation of a methane from a formic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0036315", "l": "cellular response to sterol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0035788", "l": "cell migration involved in metanephros development", "d": ["The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000961", "l": "negative regulation of mitochondrial RNA catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019759", "l": "glycosinolate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1900425", "l": "negative regulation of defense response to bacterium", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003167", "l": "atrioventricular bundle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the atrioventricular bundle. These cells are specialized cardiomyocytes that transmit signals from the AV node to the cardiac Purkinje fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0033008", "l": "positive regulation of mast cell activation involved in immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of mast cell activation as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016540", "l": "protein autoprocessing", "d": ["Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046491", "l": "L-methylmalonyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA. S-methylmalonyl-CoA is an intermediate in the beta oxidation of odd-numbered fatty acids in animals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034436", "l": "glycoprotein transport", "d": ["The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038013", "l": "positive regulation of Wnt signaling pathway by Wnt receptor internalization", "d": ["Any process in which internalization of a Wnt receptor activates or increases the frequency, rate or extent of the Wnt signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019297", "l": "coenzyme B metabolic process", "d": ["The chemical reactions and pathways involving coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.088914107493508", "identifiers": [{"i": "GO:0006766", "l": "vitamin metabolic process", "d": ["The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019552", "l": "glutamate catabolic process via 2-hydroxyglutarate", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-hydroxyglutarate, yielding energy in the form of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090017", "l": "anterior neural plate formation", "d": ["The formation of anterior end of the flat, thickened layer of ectodermal cells known as the neural plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021976", "l": "medulla reticulospinal tract morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0009268", "l": "response to pH", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901760", "l": "beta-L-Ara4N-lipid A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-L-Ara4N-lipid A which occurs as a result of modification of the lipid A moiety of lipopolysaccharide by the addition of the sugar 4-amino-4-deoxy-L-arabinose (L-Ara4N). This strategy is adopted by pathogenic Gram-negative bacteria to evade cationic antimicrobial peptides produced by the innate immune system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902599", "l": "sulfathiazole transmembrane transport", "d": ["The directed movement of sulfathiazole across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061959", "l": "response to (R)-carnitine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an (R)-carnitine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032711", "l": "negative regulation of interleukin-27 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-27 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002668", "l": "negative regulation of T cell anergy", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell anergy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0050967", "l": "detection of electrical stimulus involved in sensory perception of pain", "d": ["The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048350", "l": "positive regulation of paraxial mesodermal cell fate specification", "d": ["Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0046532", "l": "regulation of photoreceptor cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075228", "l": "positive regulation of encysted zoospore germination", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of encysted zoospore germination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032180", "l": "ubiquinone biosynthetic process from tyrosine", "d": ["The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of tyrosine to 4-hydroxybenzoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051043", "l": "regulation of membrane protein ectodomain proteolysis", "d": ["Any process that modulates the frequency, rate or extent of the proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046127", "l": "pyrimidine deoxyribonucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007066", "l": "female meiosis sister chromatid cohesion", "d": ["The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a female."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901267", "l": "cephalosporin C catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cephalosporin C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0009808", "l": "lignin metabolic process", "d": ["The chemical reactions and pathways involving lignins, a class of polymers of phenylpropanoid units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009167", "l": "purine ribonucleoside monophosphate metabolic process", "d": ["The chemical reactions and pathways involving purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905869", "l": "negative regulation of 3'-UTR-mediated mRNA stabilization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052159", "l": "modulation by symbiont of host induced systemic resistance", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060092", "l": "regulation of synaptic transmission, glycinergic", "d": ["Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0030071", "l": "regulation of mitotic metaphase/anaphase transition", "d": ["Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006670", "l": "sphingosine metabolic process", "d": ["The chemical reactions and pathways involving sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015829", "l": "valine transport", "d": ["The directed movement of valine, 2-amino-3-methylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000617", "l": "positive regulation of histone H3-K9 acetylation", "d": ["Any process that activates or increases the frequency, rate or extent of histone H3-K9 acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0042703", "l": "menstruation", "d": ["The cyclic, physiologic discharge through the vagina of blood and endometrial tissues from the nonpregnant uterus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034553", "l": "mitochondrial respiratory chain complex II assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II, in the mitochondrial inner membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0005987", "l": "sucrose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sucrose, the disaccharide fructofuranosyl-glucopyranoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0007424", "l": "open tracheal system development", "d": ["The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0097050", "l": "type B pancreatic cell apoptotic process", "d": ["Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015708", "l": "silicic acid import across plasma membrane", "d": ["The directed movement of silicates from outside of a cell, across the plasma membrane and into the cytosol. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010700", "l": "negative regulation of norepinephrine secretion", "d": ["Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060757", "l": "adult foraging behavior", "d": ["Behavior by which an adult locates food."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060855", "l": "venous endothelial cell migration involved in lymph vessel development", "d": ["The orderly movement of venous endothelial cells out of the veins giving rise to the precursors of lymphatic endothelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1903791", "l": "uracil transmembrane transport", "d": ["The process in which uracil is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010547", "l": "thylakoid membrane disassembly", "d": ["The controlled breakdown of the thylakoid membrane in the context of a normal process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003104", "l": "positive regulation of glomerular filtration", "d": ["Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060360", "l": "negative regulation of leucine import in response to ammonium ion", "d": ["Any process that decreases the rate, frequency or extent of leucine import as a result of an ammonium ion stimulus. Leucine import is the directed movement of leucine into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110032", "l": "positive regulation of G2/MI transition of meiotic cell cycle", "d": ["Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008302", "l": "female germline ring canal formation, actin assembly", "d": ["Recruitment and organization of actin filaments in female germline ring canals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0070950", "l": "regulation of neutrophil mediated killing of bacterium", "d": ["Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a bacterium, the directed killing of a bacterium by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905711", "l": "response to phosphatidylethanolamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0035917", "l": "negative regulation of calcium channel activity in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a calcium channel in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.884204812668166", "identifiers": [{"i": "GO:0032259", "l": "methylation", "d": ["The process in which a methyl group is covalently attached to a molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901207", "l": "regulation of heart looping", "d": ["Any process that modulates the frequency, rate or extent of heart looping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.644186068201407", "identifiers": [{"i": "GO:0006402", "l": "mRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0072340", "l": "lactam catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070989", "l": "oxidative demethylation", "d": ["The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901305", "l": "negative regulation of spermidine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of spermidine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006489", "l": "dolichyl diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a diphosphorylated dolichol derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0000768", "l": "syncytium formation by plasma membrane fusion", "d": ["The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035895", "l": "modulation of mast cell degranulation in another organism", "d": ["Any process in which an organism modulates the frequency, rate or extent of blood mast cell degranulation in another organism. Mast cell degranulation is the regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033661", "l": "effector-mediated defense to host-produced reactive oxygen species", "d": ["A process mediated by a molecule secreted by a symbiont that results in the suppression of reactive oxygen species produced by the host as part of its innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0097354", "l": "prenylation", "d": ["The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups may be added."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038098", "l": "sequestering of BMP from receptor via BMP binding", "d": ["Binding to a bone morphogenetic protein (BMP) in the extracellular region, and inhibiting BMP signaling by preventing BMP from binding to its cell surface receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:0050818", "l": "regulation of coagulation", "d": ["Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0002508", "l": "central tolerance induction", "d": ["Tolerance induction in the central lymphoid organs: the thymus and bone marrow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0019692", "l": "deoxyribose phosphate metabolic process", "d": ["The chemical reactions and pathways involving deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051191", "l": "prosthetic group biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006746", "l": "FADH2 metabolic process", "d": ["The chemical reactions and pathways involving the reduced form of flavin adenine dinucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075275", "l": "telium development", "d": ["The process that leads to the development of a telium, which is a teliospore-bearing sorus of the rust fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0071998", "l": "ascospore release from ascus", "d": ["A developmental process that results in the discharge of ascospores from the ascus. Ascospore release may be active or passive."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033141", "l": "positive regulation of peptidyl-serine phosphorylation of STAT protein", "d": ["Any process that activates or increases the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044827", "l": "modulation by host of viral genome replication", "d": ["A process in which a host organism modulates the frequency, rate or extent of viral genome replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045475", "l": "locomotor rhythm", "d": ["The rhythm of the locomotor activity of an organism during its 24 hour activity cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071945", "l": "regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed", "d": ["A process that modulates flagellum-dependent motility in bacteria by modulating the speed or direction of rotation of a rotary flagellar motor, mediated by interactions between the braking protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0015697", "l": "quaternary ammonium group transport", "d": ["The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140123", "l": "negative regulation of Lewy body formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Lewy body formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0075528", "l": "modulation by virus of host immune response", "d": ["The process in which a virus effects a change in the host immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0021723", "l": "medullary reticular formation development", "d": ["The process whose specific outcome is the progression of the medullary reticular formation over time, from its formation to the mature structure. The medullary reticular formation is a series of brain nuclei located in the medulla oblongata."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002797", "l": "regulation of antibacterial peptide secretion", "d": ["Any process that modulates the frequency, rate, or extent of antibacterial peptide secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075304", "l": "negative regulation of basidiospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061050", "l": "regulation of cell growth involved in cardiac muscle cell development", "d": ["Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901054", "l": "sarcosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sarcosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:2001305", "l": "xanthone-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a xanthone-containing compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019701", "l": "peptidyl-arginine N5-methylation", "d": ["The methylation of peptidyl-arginine on the internal nitrogen-5 (N5) atom (also called delta-nitrogen) to form peptidyl-N5-methyl-L-arginine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000446", "l": "regulation of macrophage migration inhibitory factor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.281967957033203", "identifiers": [{"i": "GO:0042752", "l": "regulation of circadian rhythm", "d": ["Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0071763", "l": "nuclear membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140649", "l": "cell-to-cell migration by invasive hypha", "d": ["The directional movement of a hyphal filament from one host cell to another. This process involves the clearance of plant-derived plasmodesmal occlusion materials, cytoskeleton based constriction of invasive hypha to traverse plasmodesmata. Septins and F-actin are reorganized into an hourglass shape at the point of maximum hyphal constriction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046378", "l": "enterobacterial common antigen metabolic process", "d": ["The chemical reactions and pathways involving enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0048280", "l": "vesicle fusion with Golgi apparatus", "d": ["The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0099638", "l": "endosome to plasma membrane protein transport", "d": ["The directed movement of proteins from the endosome to the plasma membrane in transport vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033080", "l": "immature T cell proliferation in thymus", "d": ["The expansion of an immature T cell population by cell division in the thymus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.958948251787156", "identifiers": [{"i": "GO:0120252", "l": "hydrocarbon metabolic process", "d": ["The chemical reactions and pathways involving a hydrocarbon, a compound consisting of carbon and hydrogen only."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072129", "l": "renal capsule formation", "d": ["The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0014074", "l": "response to purine-containing compound", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1902017", "l": "regulation of cilium assembly", "d": ["Any process that modulates the frequency, rate or extent of cilium assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044794", "l": "positive regulation by host of viral process", "d": ["A process in which a host organism activates or increases the frequency, rate or extent of the release of a process being mediated by a virus with which it is infected."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0015803", "l": "branched-chain amino acid transport", "d": ["The directed movement of branched-chain amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072236", "l": "metanephric loop of Henle development", "d": ["The process whose specific outcome is the progression of the metanephric loop of Henle over time, from its formation to the mature structure. The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048900", "l": "anterior lateral line neuromast primordium migration", "d": ["The migration of a cluster of a relatively undifferentiated cell along the developing anterior lateral line, originating from cranial ectodermal placodes situated between the eye and the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072709", "l": "cellular response to sorbitol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0043368", "l": "positive T cell selection", "d": ["The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032928", "l": "regulation of superoxide anion generation", "d": ["Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018975", "l": "anaerobic 2,4,6-trinitrotoluene metabolic process", "d": ["The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, that occur in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045325", "l": "peptidyl-tryptophan hydroxylation", "d": ["The hydroxylation of peptidyl-tryptophan, to form peptidyl-L-3-hydroxytryptophan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0018195", "l": "peptidyl-arginine modification", "d": ["The modification of peptidyl-arginine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030718", "l": "germ-line stem cell population maintenance", "d": ["Any process by which an organism or tissue maintains a population of germ-line stem cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015987", "l": "GTP synthesis coupled proton transport", "d": ["The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers GTP synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006715", "l": "farnesol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.50898652134218", "identifiers": [{"i": "GO:1901568", "l": "fatty acid derivative metabolic process", "d": ["The chemical reactions and pathways involving fatty acid derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018888", "l": "3-chloroacrylic acid metabolic process", "d": ["The chemical reactions and pathways involving 3-chloroacrylic acid, ClHC=CHCOOH, a chlorinated derivative of acrylic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904389", "l": "rod bipolar cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a rod bipolar cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.920089577627991", "identifiers": [{"i": "GO:0055074", "l": "calcium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006183", "l": "GTP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GTP, guanosine triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060984", "l": "epicardium-derived cardiac vascular smooth muscle cell development", "d": ["The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell that was derived from the epicardium over time, from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021888", "l": "hypothalamus gonadotrophin-releasing hormone neuron development", "d": ["The process whose specific outcome is the progression of a hypothalamus gonadotrophin-releasing hormone neuron over time, from initial commitment of its fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905391", "l": "regulation of protein localization to cell division site involved in cell separation after cytokinesis", "d": ["Any regulation of protein localization to cell division site that is involved in cell separation after cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018001", "l": "N-terminal peptidyl-valine acetylation", "d": ["The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-valine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003359", "l": "noradrenergic neuron fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0007128", "l": "meiotic prophase I", "d": ["The cell cycle phase which is the first stage of meiosis I and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035611", "l": "protein branching point deglutamylation", "d": ["The removal of a branching point glutamate residue. A branching point glutamate connects a glutamate side chain to a gene-encoded glutamate residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.809526531696484", "identifiers": [{"i": "GO:0001957", "l": "intramembranous ossification", "d": ["Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044331", "l": "cell-cell adhesion mediated by cadherin", "d": ["The attachment of one cell to another cell via a cadherin, transmembrane proteins having repeating extracellular calcium ion binding domains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0050942", "l": "positive regulation of pigment cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of pigment cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060910", "l": "negative regulation of DNA replication initiation involved in plasmid copy number maintenance", "d": ["Any process that decreases the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901875", "l": "positive regulation of post-translational protein modification", "d": ["Any process that activates or increases the frequency, rate or extent of post-translational protein modification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903426", "l": "regulation of reactive oxygen species biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035099", "l": "hemocyte migration", "d": ["The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900879", "l": "(Z)-nonadeca-1,14-diene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (Z)-nonadeca-1,14-diene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060427", "l": "lung connective tissue development", "d": ["The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901297", "l": "positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment", "d": ["Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051478", "l": "mannosylglycerate metabolic process", "d": ["The chemical reactions and pathways involving mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900790", "l": "pseurotin A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pseurotin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060847", "l": "endothelial cell fate specification", "d": ["The process involved in the specification of identity of an endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033599", "l": "regulation of mammary gland epithelial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048142", "l": "germarium-derived cystoblast division", "d": ["The four rounds of incomplete mitosis undergone by a cystoblast to form a 16-cell cyst of interconnected cells within a germarium. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120145", "l": "protein localization to basal ectoplasmic specialization", "d": ["A process in which a protein is transported to, or maintained in, a location within a basal ectoplasmic specialization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901882", "l": "4-hydroxycoumarin metabolic process", "d": ["The chemical reactions and pathways involving 4-hydroxycoumarin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000093", "l": "mitotic telophase", "d": ["The cell cycle phase which follows anaphase during M phase of mitosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090319", "l": "positive regulation of chylomicron remodeling", "d": ["Any process that increases the rate, frequency, or extent of chylomicron remodeling. Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002528", "l": "regulation of vascular permeability involved in acute inflammatory response", "d": ["Any process that modulates the extent to which blood vessels can be pervaded by fluid contributing to an acute inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902952", "l": "positive regulation of dendritic spine maintenance", "d": ["Any process that activates or increases the frequency, rate or extent of dendritic spine maintenance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014726", "l": "negative regulation of extraocular skeletal muscle development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034964", "l": "box H/ACA RNA processing", "d": ["Any process involved in the conversion of a primary box H/ACA type small RNA transcript into a mature box H/ACA RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036494", "l": "positive regulation of translation initiation in response to endoplasmic reticulum stress", "d": ["Any process that activates, or increases the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0072007", "l": "mesangial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the kidney as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000761", "l": "positive regulation of N-terminal peptidyl-lysine acetylation", "d": ["Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-lysine acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036277", "l": "response to anticonvulsant", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902735", "l": "negative regulation of receptor-mediated virion attachment to host cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated virion attachment to host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042464", "l": "dosage compensation by hypoactivation of X chromosome", "d": ["Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by an inactivation of a proportion of genes on both of the X chromosomes of the XX sex, leading to a decrease, of half, of the levels of gene expression from these chromosomes. An example of this process is found in Caenorhabditis elegans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048262", "l": "determination of dorsal/ventral asymmetry", "d": ["Determination of asymmetry from the dorsal to the ventral side; as, the dorsoventral axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048457", "l": "floral whorl morphogenesis", "d": ["The process in which the anatomical structures of the floral whorl are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900010", "l": "regulation of corticotropin-releasing hormone receptor activity", "d": ["Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034638", "l": "phosphatidylcholine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "48.754060233541111", "identifiers": [{"i": "GO:0000003", "l": "reproduction", "d": ["The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000683", "l": "regulation of cellular response to X-ray", "d": ["Any process that modulates the frequency, rate or extent of cellular response to X-ray."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903941", "l": "negative regulation of respiratory gaseous exchange", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051237", "l": "maintenance of RNA location", "d": ["Any process in which RNA is maintained in a location and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003366", "l": "cell-matrix adhesion involved in ameboidal cell migration", "d": ["The binding of a cell to the extracellular matrix that contributes to the directed movement of an ameboid cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046253", "l": "anaerobic toluene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030890", "l": "positive regulation of B cell proliferation", "d": ["Any process that activates or increases the rate or extent of B cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030974", "l": "thiamine pyrophosphate transmembrane transport", "d": ["The process in which thiamine pyrophosphate is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150012", "l": "positive regulation of neuron projection arborization", "d": ["Any process that activates or increases the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090360", "l": "platelet-derived growth factor production", "d": ["The appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009446", "l": "putrescine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane; putrescine can be synthesized from arginine or ornithine and is the metabolic precursor of spermidine and spermine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060622", "l": "regulation of ascospore wall beta-glucan biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of ascospore wall beta-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120132", "l": "positive regulation of apoptotic process in bone marrow cell", "d": ["Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in the bone marrow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0006591", "l": "ornithine metabolic process", "d": ["The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021701", "l": "cerebellar Golgi cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072375", "l": "medium-term memory", "d": ["The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097115", "l": "neurexin clustering involved in presynaptic membrane assembly", "d": ["The receptor clustering process involved in assembly of the presynaptic membrane in which neurexins are localized to distinct domains in the cell membrane. Neurexins are synaptic cell surface proteins which act as cell recognition molecules at nerve terminals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035523", "l": "protein K29-linked deubiquitination", "d": ["A protein deubiquitination process in which a K29-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is removed from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010727", "l": "negative regulation of hydrogen peroxide metabolic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0051279", "l": "regulation of release of sequestered calcium ion into cytosol", "d": ["Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042306", "l": "regulation of protein import into nucleus", "d": ["Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032726", "l": "positive regulation of hepatocyte growth factor production", "d": ["Any process that activates or increases the frequency, rate, or extent of hepatocyte growth factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070213", "l": "protein auto-ADP-ribosylation", "d": ["The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0006271", "l": "DNA strand elongation involved in DNA replication", "d": ["The process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000122", "l": "negative regulation of stomatal complex development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of stomatal complex development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:1902292", "l": "cell cycle DNA replication initiation", "d": ["Any DNA replication initiation that is involved in cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060094", "l": "positive regulation of synaptic transmission, glycinergic", "d": ["Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039016", "l": "cell-cell signaling involved in pronephros development", "d": ["Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009760", "l": "C4 photosynthesis", "d": ["The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) in the mesophyll cells to make a 4-carbon acid which is immediately converted to malic acid. The malic acid is then passed across to the bundle sheath cells where it is broken down again to pyruvic acid and CO2. The acid is passed back to the mesophyll cells to be used again, while the CO2 is fed into the reductive pentose-phosphate cycle (Calvin cycle) and converted into sugar and starch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044846", "l": "negative regulation by symbiont of indole acetic acid levels in host", "d": ["Any process in which an organism reduces the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903807", "l": "L-threonine import across plasma membrane", "d": ["The directed movement of L-threonine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060880", "l": "cell morphogenesis involved in semicircular canal fusion", "d": ["The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044655", "l": "phagosome reneutralization", "d": ["Any process that increases the pH of the phagosome, measured by the concentration of the hydrogen ion, as part of the process of phagosome maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075245", "l": "positive regulation of oospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0055048", "l": "anastral spindle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the absence of centrosomes. Formation is initiated by the nucleation of microtubules (MTs) in the vicinity of condensed chromatin. MTs then attach to and congress around the chromatin due to activity of microtubule motors. A bipolar spindle is formed by focusing of the terminal ends of the MT array into spindle poles by molecular motors and cross-linking proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905637", "l": "regulation of mitochondrial mRNA catabolic process", "d": ["Any process that modulates the frequency, rate or extent of mitochondrial mRNA catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902223", "l": "erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of erythrose 4-phosphate/phosphoenolpyruvate family amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0001997", "l": "positive regulation of the force of heart contraction by epinephrine-norepinephrine", "d": ["Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream or released from the nerve endings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046893", "l": "iron incorporation into hydrogenase diiron subcluster via L-cysteine ligation", "d": ["The incorporation of iron into an L-cysteinyl diiron subcluster, found in Fe-hydrogenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.56681308101922", "identifiers": [{"i": "GO:0090596", "l": "sensory organ morphogenesis", "d": ["Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075328", "l": "formation of arbuscule for nutrient acquisition", "d": ["The assembly of an arbuscule, a fine, tree-like hyphal symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902215", "l": "negative regulation of interleukin-4-mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-4-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048623", "l": "seed germination on parent plant", "d": ["The process in which a seed germinates before being shed from the parent plant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046366", "l": "allose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002409", "l": "Langerhans cell chemotaxis", "d": ["The movement of a Langerhans cell in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046957", "l": "negative phototaxis", "d": ["The directed movement of a cell or organism away from a source of light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904402", "l": "response to nocodazole", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002210", "l": "behavioral response to wounding", "d": ["A behavioral response resulting from wounding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905386", "l": "positive regulation of protein localization to presynapse", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0006113", "l": "fermentation", "d": ["The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051614", "l": "inhibition of serotonin uptake", "d": ["Any process that prevents the activation of the directed movement of serotonin into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007053", "l": "spindle assembly involved in male meiosis", "d": ["The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000010", "l": "positive regulation of protein localization to cell surface", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to the cell surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019679", "l": "propionate metabolic process, methylcitrate cycle", "d": ["The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903022", "l": "positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands", "d": ["Any process that activates or increases the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140541", "l": "piRNA transcription", "d": ["The cellular synthesis of Piwi-interacting RNA piRNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033235", "l": "positive regulation of protein sumoylation", "d": ["Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034626", "l": "fatty acid elongation, polyunsaturated fatty acid", "d": ["Elongation of a fatty acid chain into which two or more C-C double bonds have been introduced."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902514", "l": "regulation of calcium ion transmembrane transport via high voltage-gated calcium channel", "d": ["Any process that modulates the frequency, rate or extent of generation of calcium ion transmembrane transport via high voltage-gated calcium channel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015789", "l": "UDP-N-acetylgalactosamine transmembrane transport", "d": ["The directed movement of UDP-N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0003334", "l": "keratinocyte development", "d": ["The process whose specific outcome is the progression of a keratinocyte over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035044", "l": "sperm aster formation", "d": ["Formation and organization of an aster composed of microtubule arrays originating from the sperm basal body and extending virtually to the egg periphery. The sperm aster ensures the appropriate positioning of the male and female pronuclei."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0051294", "l": "establishment of spindle orientation", "d": ["Any process that set the alignment of spindle relative to other cellular structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016257", "l": "N-glycan processing to secreted and cell-surface N-glycans", "d": ["The modification of high-mannose (Man9-Asn) N-glycans by mannosyl-oligosaccharide 1,2-alpha-mannosidase. This may result in Man8GlcNAc2-Asn N-glycans (which in yeast may be subsequently modified by the addition of further mannose residues) or Man5GlcNAc2-Asn N-glycans that are substrates for further diversification in the Golgi apparatus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0015949", "l": "nucleobase-containing small molecule interconversion", "d": ["The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031282", "l": "regulation of guanylate cyclase activity", "d": ["Any process that modulates the frequency, rate or extent of guanylate cyclase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0023021", "l": "termination of signal transduction", "d": ["The signaling process in which signal transduction is brought to an end rather than being reversibly modulated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0000578", "l": "embryonic axis specification", "d": ["The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090392", "l": "sepal giant cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a sepal giant cell. A sepal giant cell is a pavement cell that is part of the sepal epidermis and stretches one fifth the length of the sepal with a chromosome content of 16C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030888", "l": "regulation of B cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of B cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.415767841334464", "identifiers": [{"i": "GO:0001944", "l": "vasculature development", "d": ["The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0002674", "l": "negative regulation of acute inflammatory response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036248", "l": "phytochelatin 4 import into vacuole", "d": ["The directed movement of phytochelatin 4 (PC4) into the vacuole. Phytochelatin 4 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=4, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002780", "l": "antibacterial peptide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an antibacterial peptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0046692", "l": "sperm competition", "d": ["Any process that contributes to the success of sperm fertilization in multiply-mated females."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903451", "l": "negative regulation of G1 to G0 transition", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of G1 to G0 transition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060550", "l": "positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity", "d": ["Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0099518", "l": "vesicle cytoskeletal trafficking", "d": ["The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002353", "l": "plasma kallikrein-kinin cascade", "d": ["A series of reactions that takes place outside the cell occurring in response to tissue damage and initiated within blood plasma by the action of activated Factor XII (Hageman Factor) on prekallikrein to convert it to plasma kallikrein, and the subsequent reaction of plasma kallikrein with high molecular weight kininogen. The ultimate product of the plasma kallikrein-kinin cascade is bradykinin, an agent known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048490", "l": "anterograde synaptic vesicle transport", "d": ["The directed movement of synaptic vesicle along axonal microtubules from the cell body to the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0045740", "l": "positive regulation of DNA replication", "d": ["Any process that activates or increases the frequency, rate or extent of DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071904", "l": "protein N-linked N-acetylgalactosaminylation via asparagine", "d": ["A process of protein N-linked glycosylation via asparagine in which N-acetylgalactosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-galactopyranosyl)amino-4-oxobutanoic acid residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046683", "l": "response to organophosphorus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organophosphorus stimulus. Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0090670", "l": "RNA localization to Cajal body", "d": ["A process in which an RNA is transported to, or maintained in, a Cajal body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990134", "l": "epithelial cell apoptotic process involved in palatal shelf morphogenesis", "d": ["An apoptotic process in a palatal shelf epithelial cell that contributes to the shaping of the palatal shelf."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007112", "l": "male meiosis cytokinesis", "d": ["A cell cycle process that occurs as part of the male meiotic cell cycle and results in the division of the cytoplasm of a cell to produce two daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018274", "l": "peptide cross-linking via L-lysinoalanine", "d": ["The modification of peptidyl-lysine and peptidyl-serine to form a (2Xi,9S)-L-lysinoalanine cross-link."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060732", "l": "positive regulation of inositol phosphate biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061753", "l": "substrate localization to autophagosome", "d": ["The localization process by which an autophagic substrate is delivered to a forming autophagosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001015", "l": "negative regulation of skeletal muscle cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038101", "l": "sequestering of nodal from receptor via nodal binding", "d": ["Binding to a nodal protein in the extracellular region, and inhibiting nodal signaling by preventing nodal from binding to its cell surface receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000847", "l": "negative regulation of corticosteroid hormone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of corticosteroid hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007504", "l": "larval fat body development", "d": ["The process whose specific outcome is the progression of the larval fat body over time, from its formation to the mature structure. The larval fat body consists of a bilaterally symmetrical monolayer of cells lying between the gut and the muscles of the body wall. As in other tissues of the larva, the cells of the fat body complete their divisions in the embryo and increase in size and ploidy during larval life."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0032808", "l": "lacrimal gland development", "d": ["The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045469", "l": "negative regulation of R8 cell spacing in compound eye", "d": ["Any process that stops or prevents the correct R8 cell spacing pattern in a compound eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044847", "l": "iron acquisition from host", "d": ["The process by which a symbiont acquires iron from its host, either from heme or other iron containing molecules such as transferrin and lactoferrin. Begins with either the secretion of symbiont gene products that bind iron- or heme-containing molecules (siderophores and hemophores) from the symbiont cell into the host, or by expression of receptors that bind iron- or heme-containing molecules on the symbiont cell surface. Ends when the iron-containing compound is transported into the symbiont cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141042", "l": "cAMP intoxication in host", "d": ["The production by a symbiont of high levels of cyclic AMP in a host cell, impairing host cellular functions in multiple ways, including ATP depletion, interference with host intracellular signaling, cytoskeletal defects and apoptosis-related cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036015", "l": "response to interleukin-3", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0034661", "l": "ncRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs). Includes the breakdown of cryptic unstable transcripts (CUTs)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030279", "l": "negative regulation of ossification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046354", "l": "mannan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043164", "l": "Gram-negative-bacterium-type cell wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Gram-negative bacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904462", "l": "ergosteryl 3-beta-D-glucoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ergosteryl 3-beta-D-glucoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021963", "l": "spinothalamic tract morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the spinothalamic tract, one of the major routes of nociceptive signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048372", "l": "lateral mesodermal cell fate commitment", "d": ["The process in which a cell becomes committed to become a lateral mesoderm cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075244", "l": "regulation of oospore formation", "d": ["Any process that modulates the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039523", "l": "suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host mRNA transcription by directly inhibiting RNA polymerase II activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900073", "l": "regulation of neuromuscular synaptic transmission", "d": ["Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990522", "l": "tail spike morphogenesis", "d": ["The process in which the nematode tail spike is generated and organized. An example of this process is seen in C. elegans, where the tapered tail spike is formed during embryogenesis by a filamentous process that passes posteriorly through hyp10, the tail ventral hypodermis; the filamentous process is formed by a binucleate cell, the tail-spike cell, that subsequently undergoes programmed cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0051349", "l": "positive regulation of lyase activity", "d": ["Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0018345", "l": "protein palmitoylation", "d": ["The covalent attachment of a palmitoyl group to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900195", "l": "positive regulation of oocyte maturation", "d": ["Any process that activates or increases the frequency, rate or extent of oocyte maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060296", "l": "regulation of cilium beat frequency involved in ciliary motility", "d": ["Any process that modulates the frequency of cilium beating involved in ciliary motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035271", "l": "ring gland development", "d": ["Progression of the ring gland over time, from its formation to a mature structure. The ring gland is a neuroendocrine organ found in higher Dipterans, which is composed of the prothoracic gland, the corpus allatum, and the corpora cardiacum. The ring gland is the site of production and release of ecdysteroids and juvenile hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006191", "l": "deoxyinosine salvage", "d": ["Any process that generates deoxyinosine from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016091", "l": "prenol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150074", "l": "positive regulation of protein-glutamine gamma-glutamyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904625", "l": "negative regulation of glycine secretion, neurotransmission", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glycine secretion, neurotransmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009750", "l": "response to fructose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000732", "l": "strand displacement", "d": ["The rejection of the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903567", "l": "regulation of protein localization to ciliary membrane", "d": ["Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048620", "l": "post-embryonic hindgut morphogenesis", "d": ["The process in which the anatomical structures of the hindgut are generated and organized, during the post-embryonic phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010218", "l": "response to far red light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060741", "l": "prostate gland stromal morphogenesis", "d": ["The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901443", "l": "negative regulation of response to furfural", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to furfural."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0035065", "l": "regulation of histone acetylation", "d": ["Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010098", "l": "suspensor development", "d": ["The process whose specific outcome is the progression of the suspensor over time, from its formation to the mature structure. The suspensor is the extension at the base of the embryo that anchors the embryo in the embryo sac and pushes it into the endosperm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090253", "l": "convergent extension involved in imaginal disc-derived wing morphogenesis", "d": ["The morphogenetic process in which the wing epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to imaginal disc-derived wing morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901585", "l": "regulation of acid-sensing ion channel activity", "d": ["Any process that modulates the frequency, rate or extent of acid-sensing ion channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060754", "l": "positive regulation of mast cell chemotaxis", "d": ["Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009716", "l": "flavonoid phytoalexin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072218", "l": "metanephric ascending thin limb development", "d": ["The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903783", "l": "negative regulation of sodium ion import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion import across the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071215", "l": "cellular response to abscisic acid stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140529", "l": "CMG complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the CMG complex, a protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication. The process begins when additional proteins (e.g. Cdc45 and Sld3) join the loaded, inactive double MCM hexamer at replication origins, and ends when Mcm10 triggers the separation of the Mcm2-7 double hexamers, forming two active CMG complexes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0048311", "l": "mitochondrion distribution", "d": ["Any process that establishes the spatial arrangement of mitochondria between and within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000523", "l": "regulation of T cell costimulation", "d": ["Any process that modulates the frequency, rate or extent of T cell costimulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0071444", "l": "cellular response to pheromone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902660", "l": "negative regulation of glucose mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucose mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060120", "l": "inner ear receptor cell fate commitment", "d": ["The process in which a cell becomes committed to become an inner ear receptor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900157", "l": "regulation of bone mineralization involved in bone maturation", "d": ["Any process that modulates the frequency, rate or extent of bone mineralization involved in bone maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150175", "l": "regulation of phosphatidylethanolamine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylethanolamine metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060629", "l": "regulation of homologous chromosome segregation", "d": ["Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048317", "l": "seed morphogenesis", "d": ["The process in which the anatomical structures of the seed are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033322", "l": "homomethionine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of homomethionine, a non-protein amino acid synthesized from methionine via chain elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0031468", "l": "nuclear membrane reassembly", "d": ["The reformation of the nuclear membranes following their breakdown in the context of a normal process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015830", "l": "diaminopimelate transport", "d": ["The directed movement of diaminopimelate, the anion of 2,6-diaminoheptanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000338", "l": "regulation of chemokine (C-X-C motif) ligand 1 production", "d": ["Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034145", "l": "positive regulation of toll-like receptor 4 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0070302", "l": "regulation of stress-activated protein kinase signaling cascade", "d": ["Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070196", "l": "eukaryotic translation initiation factor 3 complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 3 complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072126", "l": "positive regulation of glomerular mesangial cell proliferation", "d": ["Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009153", "l": "purine deoxyribonucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.008356884950679", "identifiers": [{"i": "GO:0044003", "l": "modulation by symbiont of host process", "d": ["The process in which a symbiont organism effects a change in the structure or processes of its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098729", "l": "germline stem cell symmetric division", "d": ["Division of a germline stem cell to produce two germline stem cells of the same type as the parent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072106", "l": "regulation of ureteric bud formation", "d": ["Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0006406", "l": "mRNA export from nucleus", "d": ["The directed movement of mRNA from the nucleus to the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0019042", "l": "viral latency", "d": ["The process by which, after initial infection, a virus lies dormant within a cell and viral production ceases. The process ends when the virus switches from latency and starts to replicate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140509", "l": "epithelium-like organization", "d": ["The organization of a polarized cell layer during morphogenesis in protozoa; an example is found during culmination in D. discoideum, involving alpha and beta catenins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061001", "l": "regulation of dendritic spine morphogenesis", "d": ["Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036366", "l": "transforming growth factor beta3 activation", "d": ["The release of transforming growth factor beta 3 (TGF-beta3) from its latent state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061966", "l": "establishment of left/right asymmetry", "d": ["The initial formation of the type asymmetry in an organism's body plan or part of an organism with respect to the left and right halves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045770", "l": "positive regulation of asymmetric cell division", "d": ["Any process that activates or increases the frequency, rate or extent of asymmetric cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002289", "l": "NK T cell proliferation involved in immune response", "d": ["The expansion of a NK T cell population by cell division as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036367", "l": "light adaption", "d": ["The ability of a photoreceptor to adjust to varying levels of light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033303", "l": "quercetin O-glucoside biosynthetic process", "d": ["The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of quercetin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032662", "l": "regulation of interleukin-19 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-19 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034670", "l": "chemotaxis to arachidonic acid", "d": ["The directed movement of a motile cell or organism in response to the presence of arachidonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902920", "l": "poly(hydroxyvalerate) metabolic process", "d": ["The chemical reactions and pathways involving poly(hydroxyvalerate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000703", "l": "negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051545", "l": "negative regulation of elastin biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033345", "l": "asparagine catabolic process via L-aspartate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-aspartate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002731", "l": "negative regulation of dendritic cell cytokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0072079", "l": "nephron tubule formation", "d": ["The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036183", "l": "asperthecin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019045", "l": "latent virus replication", "d": ["Any process required for latent viral replication in a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014852", "l": "regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032717", "l": "negative regulation of interleukin-8 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034107", "l": "negative regulation of erythrocyte clearance", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte clearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030541", "l": "plasmid partitioning", "d": ["Any process in which plasmids are segregated or distributed into daughter cells upon cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.760111289607934", "identifiers": [{"i": "GO:0006778", "l": "porphyrin-containing compound metabolic process", "d": ["The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901024", "l": "4-hydroxyphenylacetate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 4-hydroxyphenylacetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010137", "l": "ureide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ureide, the organic form of nitrogen in nitrogen fixing and transporting plants, from IMP, which is synthesized de novo during nitrogen fixation by roots."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051627", "l": "negative regulation of epinephrine uptake", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of epinephrine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033223", "l": "2-aminoethylphosphonate transport", "d": ["The directed movement of 2-aminoethylphosphonate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061213", "l": "positive regulation of mesonephros development", "d": ["Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034122", "l": "negative regulation of toll-like receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904384", "l": "cellular response to sodium phosphate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019245", "l": "D(-)-lactate biosynthetic process from pyruvate", "d": ["The chemical reactions and pathways resulting in the formation of D(-)-lactate from other compounds, including pyruvate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035563", "l": "positive regulation of chromatin binding", "d": ["Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021653", "l": "rhombomere 1 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 1. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009951", "l": "polarity specification of dorsal/ventral axis", "d": ["Any process resulting in the establishment of polarity along the dorsal/ventral axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001199", "l": "negative regulation of dendritic cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071964", "l": "establishment of cell polarity regulating cell shape", "d": ["Any cellular process that results in the specification or formation of a polarized intracellular organization or cell growth pattern that regulates the shape of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022620", "l": "microgametophyte vegetative cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a microgametophyte. The microgametophyte vegetative cell gives rise to the pollen tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032742", "l": "positive regulation of interleukin-19 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-19 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0042780", "l": "tRNA 3'-end processing", "d": ["The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0003407", "l": "neural retina development", "d": ["The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000236", "l": "mitotic prometaphase", "d": ["The cell cycle phase in higher eukaryotes which follows mitotic prophase and during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.651613913496419", "identifiers": [{"i": "GO:0016197", "l": "endosomal transport", "d": ["The directed movement of substances mediated by an endosome, a membrane-bounded organelle that carries materials enclosed in the lumen or located in the endosomal membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019671", "l": "glutamate catabolic process via mesaconate and citramalate", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate via the intermediates mesaconate and S-citramalate, yielding energy in the form of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048836", "l": "specification of increased petal number", "d": ["Any process that increases the number of petals produced in a developing flower."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010400", "l": "rhamnogalacturonan I side chain metabolic process", "d": ["The chemical reactions and pathways involving the side chains of the pectin, rhamnogalacturonan I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0032414", "l": "positive regulation of ion transmembrane transporter activity", "d": ["Any process that activates or increases the activity of an ion transporter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0050854", "l": "regulation of antigen receptor-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0010543", "l": "regulation of platelet activation", "d": ["Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0021595", "l": "rhombomere structural organization", "d": ["The process that contributes to the act of creating the structural organization of the rhombomere structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033601", "l": "positive regulation of mammary gland epithelial cell proliferation", "d": ["Any process that activates or increases the rate or extent of mammary gland epithelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035927", "l": "RNA import into mitochondrion", "d": ["The process in which a rRNA, ribosomal ribonucleic acid, is transported from the cytosol into the mitochondrial matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0015813", "l": "L-glutamate transmembrane transport", "d": ["The directed movement of L-glutamate across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0140205", "l": "oligopeptide import across plasma membrane", "d": ["The directed movement of an oligopeptide from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060118", "l": "vestibular receptor cell development", "d": ["The process whose specific outcome is the progression of a vestibular receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.207992593949683", "identifiers": [{"i": "GO:0007584", "l": "response to nutrient", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035854", "l": "eosinophil fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a eosinophil cell. A eosinophil is any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.456519207772914", "identifiers": [{"i": "GO:0015800", "l": "acidic amino acid transport", "d": ["The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002303", "l": "gamma-delta T cell differentiation involved in immune response", "d": ["The process in which an antigenically naive gamma-delta T cell acquires the specialized features of an effector, regulatory, or memory T cell and contributes to an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035674", "l": "tricarboxylic acid transmembrane transport", "d": ["The process in which a tricarboxylic acid is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0033073", "l": "pinene metabolic process", "d": ["The chemical reactions and pathways involving the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0048806", "l": "genitalia development", "d": ["The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072065", "l": "long descending thin limb bend development", "d": ["The process whose specific outcome is the progression of the long descending thin limb bend over time, from its formation to the mature structure. The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046118", "l": "7-methylguanosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.629619732899364", "identifiers": [{"i": "GO:1901576", "l": "organic substance biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010041", "l": "response to iron(III) ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904339", "l": "negative regulation of dopaminergic neuron differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dopaminergic neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046055", "l": "dGMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002131", "l": "wobble position cytosine ribose methylation", "d": ["The process in which the ribose of cytidine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0010109", "l": "regulation of photosynthesis", "d": ["Any process that modulates the frequency, rate or extent of photosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0007416", "l": "synapse assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904081", "l": "positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation", "d": ["Any positive regulation of transcription from RNA polymerase II promoter that is involved in neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.314728742240533", "identifiers": [{"i": "GO:0009116", "l": "nucleoside metabolic process", "d": ["The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035211", "l": "spermathecum morphogenesis", "d": ["The process in which the anatomical structures of a spermathecum, a sperm storage organ, are generated and organized. Paired spermathecae lie at the anterior end of the insect uterus on the dorsal side. Each spermatheca consists of an oval shaped capsule, connected to the uterus by a spermathecal stalk."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099156", "l": "cell-cell signaling via exosome", "d": ["Cell-cell signaling in which the ligand is carried between cells by an exosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097403", "l": "cellular response to raffinose", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903328", "l": "positive regulation of tRNA metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of tRNA metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0021522", "l": "spinal cord motor neuron differentiation", "d": ["The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051206", "l": "silicate metabolic process", "d": ["The chemical reactions and pathways involving silicates, the salts of silicic acids. Silicates are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000669", "l": "negative regulation of dendritic cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0006513", "l": "protein monoubiquitination", "d": ["Addition of a single ubiquitin group to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035142", "l": "dorsal fin morphogenesis", "d": ["The process in which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031296", "l": "B cell costimulation", "d": ["The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B cell receptor to augment B cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071026", "l": "cytoplasmic RNA surveillance", "d": ["The set of processes involved in identifying and degrading defective or aberrant RNAs within the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060624", "l": "regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process", "d": ["Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0009445", "l": "putrescine metabolic process", "d": ["The chemical reactions and pathways involving putrescine, 1,4-diaminobutane; putrescine can be formed by decarboxylation of ornithine and is the metabolic precursor of spermidine and spermine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0022416", "l": "chaeta development", "d": ["The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003069", "l": "acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure", "d": ["The process in which acetylcholine signaling causes vasodilation, resulting in a change in blood pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072183", "l": "negative regulation of nephron tubule epithelial cell differentiation", "d": ["Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007377", "l": "germ-band extension", "d": ["Elongation of the germ band on the ventral side of the embryo, accompanied by a halving in width. The elongation process pushes the posterior midgut invagination closed and compresses the amnioserosa further."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1900116", "l": "extracellular negative regulation of signal transduction", "d": ["Any negative regulation of signal transduction that takes place in extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0010454", "l": "negative regulation of cell fate commitment", "d": ["Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014877", "l": "response to muscle inactivity involved in regulation of muscle adaptation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus. This process occurs as part of the regulation of muscle adaptation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000290", "l": "deadenylation-dependent decapping of nuclear-transcribed mRNA", "d": ["Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0050765", "l": "negative regulation of phagocytosis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0032120", "l": "ascospore-type prospore membrane formation", "d": ["The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990092", "l": "calcium-dependent self proteolysis", "d": ["The calcium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009943", "l": "adaxial/abaxial axis specification", "d": ["The establishment, maintenance and elaboration of the adaxial / abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0045922", "l": "negative regulation of fatty acid metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0007549", "l": "dosage compensation", "d": ["Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0106030", "l": "neuron projection fasciculation", "d": ["The collection of neuronal projections into a bundle of rods, known as a fascicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061016", "l": "snRNA localization to Cajal body", "d": ["The directed movement of snRNA, small nuclear ribonucleic acid, to a Cajal body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903433", "l": "regulation of constitutive secretory pathway", "d": ["Any process that modulates the frequency, rate or extent of constitutive secretory pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021708", "l": "Lugaro cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature Lugaro cell. Differentiation includes the processes involved in commitment of a neuroblast to a Lugaro cell fate. A Lugaro cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075226", "l": "encysted zoospore germination", "d": ["The physiological, developmental and morphological changes that occur in an encysted zoospore, that germinates by developing a germ tube that may penetrate the host directly or indirectly through an appressorium. An encysted zoospore is a zoospore which has shed its flagellum and whose membrane has fused to form a walled cyst. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051444", "l": "negative regulation of ubiquitin-protein transferase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin transferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045668", "l": "negative regulation of osteoblast differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015842", "l": "aminergic neurotransmitter loading into synaptic vesicle", "d": ["The active transport of aminergic neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action proton pumps."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.250759876326711", "identifiers": [{"i": "GO:0031109", "l": "microtubule polymerization or depolymerization", "d": ["Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990079", "l": "cartilage homeostasis", "d": ["A tissue homeostatic process involved in the maintenance of an internal equilibrium within cartilage, including control of cellular proliferation and death and control of metabolic function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0021984", "l": "adenohypophysis development", "d": ["The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0045940", "l": "positive regulation of steroid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904286", "l": "negative regulation of protein-pyridoxal-5-phosphate linkage", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905467", "l": "positive regulation of G-quadruplex DNA unwinding", "d": ["Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA unwinding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061033", "l": "secretion by lung epithelial cell involved in lung growth", "d": ["The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099000", "l": "viral genome ejection through host cell envelope, contractile tail mechanism", "d": ["Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a contractile tail ejection system consisting of a baseplate, a central tube and an external contractile sheath.  Upon binding to the host cell surface, the baseplate changes its conformation and triggers sheath contraction, driving the rigid internal tail tube through the cell envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901395", "l": "regulation of transforming growth factor beta2 activation", "d": ["Any process that modulates the frequency, rate or extent of transforming growth factor beta2 activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060126", "l": "somatotropin secreting cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.358732272612386", "identifiers": [{"i": "GO:0016072", "l": "rRNA metabolic process", "d": ["The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097750", "l": "endosome membrane tubulation", "d": ["A membrane tubulation process occurring in an endosome membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141044", "l": "epigenetic programming in the endosperm", "d": ["The global programming of epigenetic modifications following binucleate central cell fertilization. This involves DNA methylation at the silent allele. In the endosperm, maternal genomes are hypomethylated compared with the paternal genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019441", "l": "tryptophan catabolic process to kynurenine", "d": ["The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905872", "l": "negative regulation of protein localization to cell leading edge", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000910", "l": "negative regulation of sterol import", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sterol import."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071802", "l": "negative regulation of podosome assembly", "d": ["Any process that stops, prevents or reduces the rate or extent of podosome assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003200", "l": "endocardial cushion to mesenchymal transition involved in heart chamber septation", "d": ["A transition where an endocardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the heart septum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046644", "l": "negative regulation of gamma-delta T cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905612", "l": "positive regulation of mRNA cap binding", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA cap binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044520", "l": "envenomation resulting in positive regulation of vasoactive intestinal polypeptide receptor activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0032387", "l": "negative regulation of intracellular transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0003215", "l": "cardiac right ventricle morphogenesis", "d": ["The process in which the right cardiac ventricle is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006756", "l": "AMP phosphorylation", "d": ["The process of introducing a phosphate group into AMP, adenosine monophosphate, to produce ADP. Addition of two phosphate groups produces ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061117", "l": "negative regulation of heart growth", "d": ["Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900248", "l": "negative regulation of cytoplasmic translational elongation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036108", "l": "4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0098840", "l": "protein transport along microtubule", "d": ["The directed movement of a protein along a microtubule, mediated by motor proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044500", "l": "envenomation resulting in negative regulation of blood pressure in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant decrease of the force with which blood travels through the circulatory system of the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0007320", "l": "insemination", "d": ["The introduction of semen or sperm into the genital tract of a female."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075273", "l": "positive regulation of zygosporangium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000450", "l": "negative regulation of CD8-positive, alpha-beta T cell extravasation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060165", "l": "regulation of timing of subpallium neuron differentiation", "d": ["The process controlling the timing and/or rate at which a relatively unspecialized cell in the subpallium acquires features of a neuron. The subpallium is the base region of the telencephalon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001229", "l": "negative regulation of response to gamma radiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to gamma radiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0055013", "l": "cardiac muscle cell development", "d": ["The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006592", "l": "ornithine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060262", "l": "negative regulation of N-terminal protein palmitoylation", "d": ["Any process that decreases the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071365", "l": "cellular response to auxin stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097590", "l": "archaeal-type flagellum-dependent cell motility", "d": ["Cell motility due to the motion of one or more archaeal-type flagella. An archaeal-type flagellum (also called archaellum) is a non-membrane-bounded organelle superficially similar to a bacterial-type flagellum, but having a different molecular structure and lacking a central channel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0140404", "l": "effector-mediated modulation of host innate immune response by symbiont", "d": ["A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071550", "l": "death-inducing signaling complex assembly", "d": ["A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a death domain (DD) interaction, as part of the extrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.747746368481451", "identifiers": [{"i": "GO:0036072", "l": "direct ossification", "d": ["The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070875", "l": "positive regulation of glycogen metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033478", "l": "UDP-rhamnose metabolic process", "d": ["The chemical reactions and pathways involving UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055019", "l": "negative regulation of cardiac muscle fiber development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071225", "l": "cellular response to muramyl dipeptide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051067", "l": "dihydropteridine metabolic process", "d": ["The chemical reactions and pathways involving 6,7-dihydropteridine, a bicyclic compound with the formula C6H6N4."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021815", "l": "modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration", "d": ["Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097046", "l": "replication fork progression beyond termination site", "d": ["Regulation of DNA replication by a mechanism that allows a DNA replication fork to progress beyond a termination site, which is a region containing fork pausing elements that influence the progression and merging of DNA replication forks."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032700", "l": "negative regulation of interleukin-17 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.240853996207278", "identifiers": [{"i": "GO:1902532", "l": "negative regulation of intracellular signal transduction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072739", "l": "response to anisomycin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900080", "l": "positive regulation of arginine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of arginine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.651613913496419", "identifiers": [{"i": "GO:0007612", "l": "learning", "d": ["Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075139", "l": "response to host iron concentration", "d": ["Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting iron concentration in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010377", "l": "guard cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a stomatal guard cell. Guard cells are located in the leaf epidermis and pairwise surround stomatal pores, which allow CO2 influx for photosynthetic carbon fixation and water loss via transpiration to the atmosphere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900866", "l": "glycolate transport", "d": ["The directed movement of a glycolate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140159", "l": "borate export across plasma membrane", "d": ["The directed movement of borate from inside of a cell, across the plasma membrane and into the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042458", "l": "nopaline catabolic process to proline", "d": ["The chemical reactions and pathways resulting in the breakdown of nopaline into other compounds, including proline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900534", "l": "palmitic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of palmitic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0001946", "l": "lymphangiogenesis", "d": ["Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003023", "l": "baroreceptor detection of increased arterial stretch", "d": ["The series of events by which an increase in diameter of an artery is detected and converted to a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018161", "l": "dipyrrin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043584", "l": "nose development", "d": ["The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001110", "l": "negative regulation of lens epithelial cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lens epithelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904060", "l": "negative regulation of locomotor rhythm", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of locomotor rhythm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0072595", "l": "maintenance of protein localization in organelle", "d": ["Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007524", "l": "adult visceral muscle development", "d": ["The process whose specific outcome is the progression of the adult visceral muscle over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075519", "l": "microtubule-dependent intracellular transport of viral material", "d": ["The directed movement of the viral genome or viral particle within the host cell cytoplasm along host microtubules. Microtubule-dependent transport involves motor proteins like dynein and kinesin and is mostly used by viruses that target their genomes to the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021638", "l": "trigeminal nerve formation", "d": ["The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032211", "l": "negative regulation of telomere maintenance via telomerase", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0086029", "l": "Purkinje myocyte to ventricular cardiac muscle cell signaling", "d": ["Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044628", "l": "positive regulation of complement activation, classical pathway in another organism", "d": ["Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway, in a different organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061358", "l": "negative regulation of Wnt protein secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a Wnt protein from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030206", "l": "chondroitin sulfate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903357", "l": "regulation of transcription initiation by RNA polymerase I", "d": ["Any process that modulates the frequency, rate or extent of transcription initiation from RNA polymerase I promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901835", "l": "positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA", "d": ["Any process that activates or increases the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901810", "l": "beta-carotene metabolic process", "d": ["The chemical reactions and pathways involving beta-carotene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0010658", "l": "striated muscle cell apoptotic process", "d": ["A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019469", "l": "octopine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of octopine (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045113", "l": "regulation of integrin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900492", "l": "negative regulation of [4Fe-4S] cluster assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of [4Fe-4S] cluster assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051986", "l": "negative regulation of attachment of spindle microtubules to kinetochore", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903080", "l": "regulation of C-C chemokine receptor CCR7 signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000353", "l": "positive regulation of endothelial cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0015669", "l": "gas transport", "d": ["The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021818", "l": "modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex radial glia guided migration", "d": ["The changes in the actin cytoskeleton that are necessary for the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075523", "l": "viral translational frameshifting", "d": ["A process which occurs during viral translation, which involves a translational recoding mechanism called programmed ribosomal frameshifting. This causes the ribosome to alter its reading of the mRNA to an a different open reading frame to produce alternate viral proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0046458", "l": "hexadecanal metabolic process", "d": ["The chemical reactions and pathways involving hexadecanal, the C16 straight chain aldehyde."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018990", "l": "ecdysis, chitin-based cuticle", "d": ["The shedding of the old chitin-based cuticlar fragments during the molting cycle. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060617", "l": "positive regulation of mammary placode formation by mesenchymal-epithelial signaling", "d": ["Any process that initiates the formation of a mammary placode through a mechanism that mediates the transfer of information from a mesenchymal cell to an epithelial cell resulting in the epithelial cell adopting the identity of a cell of the mammary placode."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035073", "l": "pupariation", "d": ["The onset of prepupal development when the larval stops crawling, everts its spiracles and the larval cuticle becomes the puparium or pupal case that surrounds the organism for the duration of metamorphosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019697", "l": "L-xylitol catabolic process to xylulose 5-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-xylitol to form xylulose 5-phosphate. L-xylitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070583", "l": "spore membrane bending pathway", "d": ["The process in which a bending force is generated in the prospore membrane to form the characteristic curved shape of the prospore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000769", "l": "syncytium formation by mitosis without cytokinesis", "d": ["The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by one or more rounds of nuclear division without cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044470", "l": "envenomation resulting in negative regulation of blood coagulation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of blood coagulation in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0046643", "l": "regulation of gamma-delta T cell activation", "d": ["Any process that modulates the frequency, rate or extent of gamma-delta T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019311", "l": "sorbose metabolic process", "d": ["The chemical reactions and pathways involving sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070454", "l": "negative regulation of heme biosynthetic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006809", "l": "nitric oxide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2000199", "l": "positive regulation of ribonucleoprotein complex localization", "d": ["Any process that activates or increases the frequency, rate or extent of ribonucleoprotein complex localization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051894", "l": "positive regulation of focal adhesion assembly", "d": ["Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021735", "l": "dentate nucleus development", "d": ["The process whose specific outcome is the progression of the dentate nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0033006", "l": "regulation of mast cell activation involved in immune response", "d": ["Any process that modulates the frequency, rate, or extent of mast cell activation as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071895", "l": "odontoblast differentiation", "d": ["The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0015810", "l": "aspartate transmembrane transport", "d": ["The process in which aspartate is transported across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904926", "l": "response to palmitoleic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075325", "l": "spore dispersal", "d": ["Any process in which an organism disseminates its spores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032648", "l": "regulation of interferon-beta production", "d": ["Any process that modulates the frequency, rate, or extent of interferon-beta production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140964", "l": "intracellular auxin homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of auxin within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900659", "l": "negative regulation of emericellamide biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052156", "l": "modulation by symbiont of host T-cell mediated immune response", "d": ["Any process in which an organism modulates the frequency, rate or extent of the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1900620", "l": "acetate ester biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an acetate esteran acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904263", "l": "positive regulation of TORC1 signaling", "d": ["Any process that activates or increases the frequency, rate or extent of TORC1 signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900559", "l": "austinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of austinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2001169", "l": "regulation of ATP biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of ATP biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072737", "l": "response to diamide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036008", "l": "sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds by phosphorylation of sucrose to form sucrose-6-phosphate. The subsequent actions of a hydrolase and a fructokinase generate fructose-6-phosphate and glucose-6-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900698", "l": "regulation of o-orsellinic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of o-orsellinic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0036336", "l": "dendritic cell migration", "d": ["The movement of a dendritic cell within or between different tissues and organs of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072220", "l": "metanephric descending thin limb development", "d": ["The process whose specific outcome is the progression of the metanephric descending thin limb over time, from its formation to the mature structure. The metanephric descending thin limb is a part of the metanephric loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the metanephric loop of Henle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0033523", "l": "histone H2B ubiquitination", "d": ["The modification of histone H2B by addition of ubiquitin groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0009813", "l": "flavonoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of flavonoids, a group of phenolic derivatives containing a flavan skeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903032", "l": "negative regulation of microtubule plus-end binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microtubule plus-end binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042949", "l": "arbutin transport", "d": ["The directed movement of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071562", "l": "nucleus-vacuole junction assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a nucleus-vacuole junction (NVJ), membrane contact sites formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p. The NVJ plays roles in piecemeal microautophagy of the nucleus and in the cytoplasm-to-vacuole targeting pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150036", "l": "regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission", "d": ["Any process that modulates the frequency, rate or extent of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062236", "l": "ionocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an ionocyte. Ionocytes are specialized epithelial cells that contribute to osmotic homeostasis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019333", "l": "denitrification pathway", "d": ["The reduction of nitrate to dinitrogen by four reactions; each intermediate is transformed to the next lower oxidation state; also part of cellular bioenergetics; the nitrogen compounds can serve as terminal acceptors for electron transport phosphorylation in place of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032263", "l": "GMP salvage", "d": ["Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.470455508855807", "identifiers": [{"i": "GO:0005996", "l": "monosaccharide metabolic process", "d": ["The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031448", "l": "positive regulation of fast-twitch skeletal muscle fiber contraction", "d": ["Any process that activates or increases the frequency, rate or extent of fast-twitch skeletal muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010190", "l": "cytochrome b6f complex assembly", "d": ["Formation of cytochrome b6f complex, a complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen, by the aggregation, arrangement and bonding together of its constituents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0042362", "l": "fat-soluble vitamin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106210", "l": "culmorin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of culmorin, a sesquiterpenoid fungal metabolite and mycotoxin produced by some ascomycete species such as Fusarium culmorum, F. graminearum, F. venenatum and Leptosphaeria oraemaris."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1990891", "l": "mitotic sister chromatid arm separation", "d": ["The cell cycle process in which sister chromatid arms are physically detached from each other during mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060117", "l": "auditory receptor cell development", "d": ["The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046254", "l": "anaerobic toluene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0002861", "l": "regulation of inflammatory response to antigenic stimulus", "d": ["Any process that modulates the frequency, rate, or extent of an inflammatory response to an antigenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0030073", "l": "insulin secretion", "d": ["The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000485", "l": "regulation of glutamine transport", "d": ["Any process that modulates the frequency, rate or extent of glutamine transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034258", "l": "nicotinamide riboside transport", "d": ["The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106022", "l": "positive regulation of vesicle docking", "d": ["Any process that activates or increases the frequency, rate or extent of vesicle docking."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900069", "l": "regulation of cellular hyperosmotic salinity response", "d": ["Any process that modulates the frequency, rate or extent of cellular hyperosmotic salinity response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034157", "l": "positive regulation of toll-like receptor 7 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 7 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000879", "l": "negative regulation of dipeptide transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160006", "l": "Fc receptor-mediated immune complex endocytosis", "d": ["An endocytosis process mediated by the Fc receptor for the purpose of delivery of antigen-bound immunoglobulin to an intracellular compartment where the antigen can be processed and loaded onto MHC molecules. This process selectively targets antigens for presentation by MHC class II or cross-presentation by MHC class I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051756", "l": "meiotic sister chromatid centromere separation", "d": ["The cell cycle process in which the centromeres of sister chromatids are physically detached from each other during meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900927", "l": "negative regulation of L-threonine import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-threonine import into cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.378002841413903", "identifiers": [{"i": "GO:0006873", "l": "intracellular monoatomic ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of monoatomic ions within a cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044509", "l": "envenomation resulting in modulation of signal transduction in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of signal transduction in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905272", "l": "negative regulation of proton-transporting ATP synthase activity, rotational mechanism", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071399", "l": "cellular response to linoleic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900097", "l": "positive regulation of dosage compensation by inactivation of X chromosome", "d": ["Any process that activates or increases the frequency, rate or extent of dosage compensation, by inactivation of X chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:2000060", "l": "positive regulation of ubiquitin-dependent protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.850028330009977", "identifiers": [{"i": "GO:0007498", "l": "mesoderm development", "d": ["The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0044417", "l": "translocation of molecules into host", "d": ["The directed movement of a molecule(s) produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0033530", "l": "raffinose metabolic process", "d": ["The chemical reactions and pathways involving raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901330", "l": "negative regulation of odontoblast differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990690", "l": "Golgi medial cisterna-derived vesicle fusion with Golgi cis cisterna membrane", "d": ["The joining of the lipid bilayer membrane around a Golgi medial cisterna-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0043400", "l": "cortisol secretion", "d": ["The regulated release of cortisol, a steroid hormone that in humans is the major circulating hormone of the cortex, or outer layer, of the adrenal gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904076", "l": "regulation of estrogen biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of estrogen biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901787", "l": "benzoyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving benzoyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090604", "l": "surface biofilm formation", "d": ["A process in which planktonically growing microorganisms grow at the surface of a liquid-air interface and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.722653756574275", "identifiers": [{"i": "GO:0032446", "l": "protein modification by small protein conjugation", "d": ["A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990383", "l": "cellular response to biotin starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of biotin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900351", "l": "regulation of methanofuran biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of methanofuran biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002567", "l": "somatic diversification of FREP-based immune receptors", "d": ["The process that results in the generation of sequence diversity of the FREP-based immune receptors of snails."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090154", "l": "positive regulation of sphingolipid biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000511", "l": "regulation of granzyme A production", "d": ["Any process that modulates the frequency, rate or extent of granzyme A production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098001", "l": "receptor-mediated bacteriophage reversible attachment to host cell", "d": ["Process by which a bacteriophage, using its tail fibers, spikes or a baseplate component, initially recognizes and binds to its specific receptor on the host cell surface. This process is reversible and allows the release of a bacteriophage without affecting infection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002010", "l": "excitation of vasomotor center by baroreceptor signaling", "d": ["The process in which the molecular signal from the arterial baroreceptors is relayed to the vasomotor center causing it to signal increase arterial pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051141", "l": "negative regulation of NK T cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0019527", "l": "pentitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pentitols, any alditol with a chain of five carbon atoms in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905478", "l": "regulation of glutamate-ammonia ligase activity", "d": ["Any process that modulates the frequency, rate or extent of glutamate-ammonia ligase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904857", "l": "regulation of endothelial cell chemotaxis to vascular endothelial growth factor", "d": ["Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0021593", "l": "rhombomere morphogenesis", "d": ["The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903138", "l": "negative regulation of cell wall integrity MAPK cascade", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045611", "l": "negative regulation of hemocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of hemocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0002483", "l": "antigen processing and presentation of endogenous peptide antigen", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019303", "l": "D-ribose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110160", "l": "negative regulation of mitotic spindle formation (spindle phase one)", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904177", "l": "regulation of adipose tissue development", "d": ["Any process that modulates the frequency, rate or extent of adipose tissue development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903393", "l": "positive regulation of adherens junction organization", "d": ["Any process that activates or increases the frequency, rate or extent of adherens junction organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0090224", "l": "regulation of spindle organization", "d": ["Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.651716354923636", "identifiers": [{"i": "GO:0048812", "l": "neuron projection morphogenesis", "d": ["The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000105", "l": "histidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.260243218047506", "identifiers": [{"i": "GO:0140014", "l": "mitotic nuclear division", "d": ["A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900169", "l": "regulation of glucocorticoid mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of glucocorticoid mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900052", "l": "regulation of retinoic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of retinoic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002916", "l": "positive regulation of central B cell anergy", "d": ["Any process that activates or increases the frequency, rate, or extent of central B cell anergy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.819490397197882", "identifiers": [{"i": "GO:0007062", "l": "sister chromatid cohesion", "d": ["The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000790", "l": "regulation of mesenchymal cell proliferation involved in lung development", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046753", "l": "non-lytic viral release", "d": ["The exit of a viral particle from a host cell that does not involve cell lysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033071", "l": "vancomycin metabolic process", "d": ["The chemical reactions and pathways involving vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060678", "l": "dichotomous subdivision of terminal units involved in ureteric bud branching", "d": ["The process in which a ureteric bud bifurcates at its end."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071792", "l": "bacillithiol metabolic process", "d": ["The chemical reactions and pathways involving bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000526", "l": "positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation", "d": ["Any positive regulation of glycoprotein biosynthetic process that is involved in immunological synapse formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070485", "l": "dehydro-D-arabinono-1,4-lactone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019272", "l": "L-alanine biosynthetic process from pyruvate", "d": ["The chemical reactions and pathways resulting in the formation of alanine from other compounds, including pyruvate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006792", "l": "regulation of sulfur utilization", "d": ["Any process that modulates the frequency, rate or extent of sulfur utilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033359", "l": "lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate", "d": ["The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and N-succinyl-2-amino-6-ketopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0008347", "l": "glial cell migration", "d": ["The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0045824", "l": "negative regulation of innate immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009972", "l": "cytidine deamination", "d": ["The removal of amino group in the presence of water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021870", "l": "Cajal-Retzius cell differentiation", "d": ["The process in which a neuroblast acquires specialized structural and/or functional features of a Cajal-Retzius cell, one of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140974", "l": "cellular detoxification of sulfide", "d": ["Any process carried out at the cellular level that reduces or removes the toxicity of a sulfide. These may include chemical modification or transport of sulfide away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038020", "l": "insulin receptor recycling", "d": ["The process that results in the return of an insulin receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive an insulin signal. Internalized insulin receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060254", "l": "regulation of N-terminal protein palmitoylation", "d": ["Any process that modulates the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0018230", "l": "peptidyl-L-cysteine S-palmitoylation", "d": ["The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043099", "l": "pyrimidine deoxyribonucleoside salvage", "d": ["Any process that generates a pyrimidine deoxyribonucleoside from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990519", "l": "pyrimidine nucleotide import into mitochondrion", "d": ["The process in which a pyrimidine nucleotide is transported across the mitochondrial inner membrane, into the mitochondrial matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003092", "l": "renal water retention", "d": ["The process in which renal water excretion is decreased."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045218", "l": "zonula adherens maintenance", "d": ["Maintaining the zonula adherens junction, the cell-cell adherens junction formed near the apex of epithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.759589091987948", "identifiers": [{"i": "GO:0008219", "l": "cell death", "d": ["Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "43.714094008731877", "identifiers": [{"i": "GO:1901360", "l": "organic cyclic compound metabolic process", "d": ["The chemical reactions and pathways involving organic cyclic compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032683", "l": "negative regulation of connective tissue growth factor production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of connective tissue growth factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0000725", "l": "recombinational repair", "d": ["A DNA repair process that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous DNA region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0061181", "l": "regulation of chondrocyte development", "d": ["Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904328", "l": "regulation of myofibroblast contraction", "d": ["Any process that modulates the frequency, rate or extent of myofibroblast contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902011", "l": "poly(ribitol phosphate) teichoic acid metabolic process", "d": ["The chemical reactions and pathways involving poly(ribitol phosphate) teichoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.594043123901756", "identifiers": [{"i": "GO:0043270", "l": "positive regulation of monoatomic ion transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902033", "l": "regulation of hematopoietic stem cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.68653737057361", "identifiers": [{"i": "GO:0008643", "l": "carbohydrate transport", "d": ["The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033602", "l": "negative regulation of dopamine secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0051418", "l": "microtubule nucleation by microtubule organizing center", "d": ["The 'de novo' formation of a microtubule, mediated by the microtubule organizing center."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0001889", "l": "liver development", "d": ["The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0070344", "l": "regulation of fat cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of fat cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060226", "l": "negative regulation of retinal cone cell fate commitment", "d": ["Any process that increases the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0031453", "l": "positive regulation of heterochromatin formation", "d": ["Any process that activates or increases the frequency, rate or extent of heterochromatin formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903675", "l": "negative regulation of cap-dependent translational initiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cap-dependent translational initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0098743", "l": "cell aggregation", "d": ["The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030255", "l": "protein secretion by the type IV secretion system", "d": ["The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type IV protein secretion system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.008356884950679", "identifiers": [{"i": "GO:0031329", "l": "regulation of cellular catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003213", "l": "cardiac right atrium morphogenesis", "d": ["The process in which the right cardiac atrium is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060954", "l": "neural crest-derived cardiac glial cell development", "d": ["The process aimed at the progression of a neural crest-derived cardiac glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904410", "l": "negative regulation of secretory granule organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000431", "l": "regulation of transcription from RNA polymerase II promoter by galactose", "d": ["Any process involving galactose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:2000402", "l": "negative regulation of lymphocyte migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.760111289607934", "identifiers": [{"i": "GO:0061005", "l": "cell differentiation involved in kidney development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0055046", "l": "microgametogenesis", "d": ["The process whose specific outcome is the progression of the pollen grain over time, from its formation as the microspore to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0006636", "l": "unsaturated fatty acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009147", "l": "pyrimidine nucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046183", "l": "L-idonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903061", "l": "positive regulation of protein lipidation", "d": ["Any process that activates or increases the frequency, rate or extent of protein lipidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903471", "l": "regulation of mitotic actomyosin contractile ring contraction", "d": ["Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903723", "l": "negative regulation of centriole elongation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of centriole elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001692", "l": "histamine metabolic process", "d": ["The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010590", "l": "regulation of septum digestion after cytokinesis", "d": ["Any process that modulates the rate, frequency or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002271", "l": "plasmacytoid dendritic cell activation involved in immune response", "d": ["A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045985", "l": "positive regulation of pyrimidine nucleobase metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072633", "l": "interleukin-30 production", "d": ["The appearance of interleukin-30 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035565", "l": "regulation of pronephros size", "d": ["Any process that modulates the size of a pronephric kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060273", "l": "crying behavior", "d": ["The behavior in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905768", "l": "negative regulation of double-stranded telomeric DNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of double-stranded telomeric DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048723", "l": "clypeus development", "d": ["The process whose specific outcome is the progression of the clypeus over time, from its formation to the mature structure. The clypeus is the shield-shaped plate on an insect's head."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001035", "l": "regulation of tongue muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0042102", "l": "positive regulation of T cell proliferation", "d": ["Any process that activates or increases the rate or extent of T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006016", "l": "2-deoxyribose 1-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090107", "l": "regulation of high-density lipoprotein particle assembly", "d": ["Any process that modulates the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904357", "l": "negative regulation of telomere maintenance via telomere lengthening", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0086028", "l": "bundle of His cell to Purkinje myocyte signaling", "d": ["Any process that mediates the transfer of information from a bundle of His cardiomyocyte to a Purkinje myocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042453", "l": "deoxyguanosine metabolic process", "d": ["The chemical reactions and pathways involving deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905099", "l": "positive regulation of guanyl-nucleotide exchange factor activity", "d": ["Any process that activates or increases the frequency, rate or extent of guanyl-nucleotide exchange factor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031584", "l": "activation of phospholipase D activity", "d": ["Any process that initiates the activity of inactive phospholipase D."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002534", "l": "cytokine production involved in inflammatory response", "d": ["The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000201", "l": "negative regulation of ribosomal subunit export from nucleus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal subunit export from nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072045", "l": "convergent extension involved in nephron morphogenesis", "d": ["The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0099545", "l": "trans-synaptic signaling by trans-synaptic complex", "d": ["Cell-cell signaling between presynapse and postsynapse mediated by a trans-synaptic protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097438", "l": "exit from dormancy", "d": ["The dormancy process that results in exit from dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036236", "l": "acyl glucuronidation", "d": ["The modification of an substrate by the conjugation of glucuronic acid to form an acyl-glucuronide (also called an acyl-glucuronoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014834", "l": "skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration", "d": ["Any process by which the number of skeletal muscle satellite cells in a skeletal muscle is maintained during muscle regeneration. There are at least three mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells. Some adult skeletal muscle myoblasts (descendants of activated satellite cells) can develop back into quiescent satellite cells, replenishing the overall pool of satellite cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045599", "l": "negative regulation of fat cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001096", "l": "cellotriose transport", "d": ["The directed movement of a cellotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071238", "l": "cellular response to brefeldin A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990044", "l": "protein localization to lipid droplet", "d": ["A process in which a protein is transported to, or maintained in, a location on or within a lipid droplet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048835", "l": "specification of decreased petal number", "d": ["Any process that reduces the number of petals produced in a developing flower."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900125", "l": "regulation of hyaluronan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900609", "l": "F-9775A metabolic process", "d": ["The chemical reactions and pathways involving F-9775A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000389", "l": "regulation of neutrophil extravasation", "d": ["Any process that modulates the frequency, rate or extent of neutrophil extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901300", "l": "positive regulation of hydrogen peroxide-mediated programmed cell death", "d": ["Any process that activates or increases the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061116", "l": "ductus venosus closure", "d": ["The morphogenesis process in which the ductus venosus changes to no longer permit blood flow after birth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0006582", "l": "melanin metabolic process", "d": ["The chemical reactions and pathways involving melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035289", "l": "posterior head segmentation", "d": ["Partitioning the posterior region of the insect head anlage into gnathal (mandibular, maxillary and labial) segments. Unlike the anterior head (procephalic) segments, formation of the posterior head (gnathal) segments occurs by a similar mechanism to trunk segmentation, where a cascade of gap genes, pair-rule genes and segment-polarity genes subdivide the embryo into progressively smaller domains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010983", "l": "positive regulation of high-density lipoprotein particle clearance", "d": ["Any process that increases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071457", "l": "cellular response to ozone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0048737", "l": "imaginal disc-derived appendage development", "d": ["The process whose specific outcome is the progression of an appendage over time, from its formation in the imaginal disc to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018258", "l": "protein O-linked glycosylation via hydroxyproline", "d": ["The glycosylation of proteins via 04 atom of hydroxyproline to form O4-glycosyl-L-hydroxyproline; the most common form is arabinofuranosyl-4-proline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0021575", "l": "hindbrain morphogenesis", "d": ["The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098658", "l": "inorganic anion import across plasma membrane", "d": ["The directed movement of inorganic anions from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034053", "l": "modulation by symbiont of host defense-related programmed cell death", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046083", "l": "adenine metabolic process", "d": ["The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902247", "l": "geranylgeranyl diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of geranylgeranyl diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097112", "l": "gamma-aminobutyric acid receptor clustering", "d": ["The receptor clustering process in which gamma-aminobutyric acid (GABA) receptors are localized to distinct domains in the cell membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032723", "l": "positive regulation of connective tissue growth factor production", "d": ["Any process that activates or increases the frequency, rate, or extent of connective tissue growth factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019511", "l": "peptidyl-proline hydroxylation", "d": ["The hydroxylation of peptidyl-proline to form peptidyl-hydroxyproline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902092", "l": "positive regulation of fumagillin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of fumagillin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046293", "l": "formaldehyde biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of formaldehyde (methanal, H2C=O), the simplest aldehyde."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010510", "l": "regulation of acetyl-CoA biosynthetic process from pyruvate", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042023", "l": "DNA endoreduplication", "d": ["Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046147", "l": "tetrahydrobiopterin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905675", "l": "negative regulation of adaptive immune memory response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune memory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018221", "l": "peptidyl-serine palmitoylation", "d": ["The covalent attachment of a palmitoyl group to an oxygen (O) atom in a serine residue to form peptidyl-O-palmitoyl-L-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000445", "l": "positive regulation of toll-like receptor 21 signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of toll-like receptor 21 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0051329", "l": "mitotic interphase", "d": ["The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072627", "l": "interleukin-28A production", "d": ["The appearance of interleukin-28A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042817", "l": "pyridoxal metabolic process", "d": ["The chemical reactions and pathways involving 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048464", "l": "flower calyx development", "d": ["The process whose specific outcome is the progression of the flower calyx over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0030194", "l": "positive regulation of blood coagulation", "d": ["Any process that activates or increases the frequency, rate or extent of blood coagulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021804", "l": "negative regulation of cell adhesion in ventricular zone", "d": ["The process that results in the loss of attachments of a cell in the ventricular zone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019524", "l": "keto-D-gluconate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043326", "l": "chemotaxis to folate", "d": ["The directed movement of a motile cell or organism in response to the presence of folate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990680", "l": "response to melanocyte-stimulating hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a melanocyte-stimulating hormone stimulus. The binding of any one of three melanocyte-stimulating hormones causes dispersal of melanosomes in melanophores of poikilothermic vertebrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039675", "l": "exit of virus from host cell nucleus through nuclear pore", "d": ["The directed movement of the viral genome or a viral particle out of the host cell nucleus through the nuclear pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009249", "l": "protein lipoylation", "d": ["The lipoylation of peptidyl-lysine to form peptidyl-N6-lipoyl-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.646043506621545", "identifiers": [{"i": "GO:0098771", "l": "inorganic ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0006874", "l": "intracellular calcium ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of calcium ions within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035223", "l": "leg disc pattern formation", "d": ["The process that gives rise to the patterns of cell differentiation in the leg imaginal disc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902511", "l": "negative regulation of apoptotic DNA fragmentation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0033212", "l": "iron import into cell", "d": ["The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901846", "l": "positive regulation of cell communication by electrical coupling involved in cardiac conduction", "d": ["Any process that activates or increases the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010378", "l": "temperature compensation of the circadian clock", "d": ["The process in which the circadian clock maintains robust and accurate timing over a broad range of physiological temperatures. The circadian clock is an endogenous 24-h timer found in most eukaryotes and in photosynthetic bacteria. The clock drives rhythms in the physiology, biochemistry, and metabolism of the organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0050960", "l": "detection of temperature stimulus involved in thermoception", "d": ["The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902348", "l": "cellular response to strigolactone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070249", "l": "positive regulation of natural killer cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer cell death by apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061006", "l": "regulation of cell proliferation involved in kidney morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009190", "l": "cyclic nucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032202", "l": "telomere assembly", "d": ["A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a telomere at a non-telomeric double-stranded DNA end. A telomere is a terminal region of a linear chromosome that includes telomeric DNA repeats and associated proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000475", "l": "negative regulation of opioid receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of opioid receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048061", "l": "positive gravitaxis", "d": ["The directed movement of a motile cell or organism towards the source of gravity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0002413", "l": "tolerance induction to tumor cell", "d": ["A process of tolerance induction which leads to immunological tolerance of a tumor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0009726", "l": "detection of endogenous stimulus", "d": ["The series of events in which an endogenous stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006795", "l": "regulation of phosphorus utilization", "d": ["Any process that modulates the frequency, rate or extent of phosphorus utilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051987", "l": "positive regulation of attachment of spindle microtubules to kinetochore", "d": ["Any process that activates or increases the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140239", "l": "postsynaptic endocytosis", "d": ["A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072192", "l": "ureter epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell in the urothelium. The urothelium is the epithelial tube of the ureter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905358", "l": "positive regulation of snRNA pseudouridine synthesis", "d": ["Any process that activates or increases the frequency, rate or extent of snRNA pseudouridine synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0006598", "l": "polyamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of polyamines, any organic compound containing two or more amino groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990466", "l": "protein autosumoylation", "d": ["The sumoylation by a protein of one or more of its own amino acid residues, or residues on an identical protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061321", "l": "garland nephrocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0071467", "l": "cellular response to pH", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.523519163150823", "identifiers": [{"i": "GO:0001708", "l": "cell fate specification", "d": ["The cellular developmental process involved in cell fate commitment in which the cell is designated to follow a developmental path, unless they receive extrinsic cues that direct an alternative fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0075296", "l": "positive regulation of ascospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035813", "l": "regulation of renal sodium excretion", "d": ["Any process that modulates the amount of sodium excreted in urine over a unit of time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900334", "l": "negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0097052", "l": "L-kynurenine metabolic process", "d": ["The chemical reactions and pathways involving L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900912", "l": "negative regulation of olefin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of olefin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.934843701089072", "identifiers": [{"i": "GO:0042127", "l": "regulation of cell population proliferation", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902548", "l": "negative regulation of cellular response to vascular endothelial growth factor stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902481", "l": "gamma-tubulin complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a gamma-tubulin complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0072393", "l": "microtubule anchoring at microtubule organizing center", "d": ["Any process in which a microtubule is maintained in a specific location in a cell by attachment to a microtubule organizing center."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000992", "l": "negative regulation of galactomannan catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of galactomannan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097752", "l": "regulation of DNA stability", "d": ["Any process that modulates the stability of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002241", "l": "response to parasitic plant", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a parasitic plant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060252", "l": "positive regulation of glial cell proliferation", "d": ["Any process that activates or increases the rate or extent of glial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0042359", "l": "vitamin D metabolic process", "d": ["The chemical reactions and pathways involving vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097066", "l": "response to thyroid hormone", "d": ["A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0003348", "l": "cardiac endothelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036149", "l": "phosphatidylinositol acyl-chain remodeling", "d": ["Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation reactions, to generate phosphatidylinositol containing different types of fatty acid acyl chains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0032147", "l": "activation of protein kinase activity", "d": ["Any process that initiates the activity of an inactive protein kinase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001232", "l": "positive regulation of protein localization to prospore membrane", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to prospore membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018957", "l": "phenanthrene catabolic process via trans-9(S),10(S)-dihydrodiolphenanthrene", "d": ["The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(S),10(S)-dihydrodiolphenanthrene is the principal intermediate metabolite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0060711", "l": "labyrinthine layer development", "d": ["The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903589", "l": "positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051038", "l": "negative regulation of transcription involved in meiotic cell cycle", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of transcription involved in the meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070502", "l": "capsule poly-gamma-glutamate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds, that forms all or part of a bacterial capsule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048363", "l": "mucilage pectin metabolic process", "d": ["The chemical reactions and pathways involving the pectin component of mucilage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0045685", "l": "regulation of glial cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of glia cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.358732272612386", "identifiers": [{"i": "GO:0050000", "l": "chromosome localization", "d": ["Any process in which a chromosome is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019354", "l": "siroheme biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071783", "l": "endoplasmic reticulum cisternal network organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902344", "l": "negative regulation of maltose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maltose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072278", "l": "metanephric comma-shaped body morphogenesis", "d": ["The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035090", "l": "maintenance of apical/basal cell polarity", "d": ["Retaining the established polarization of a cell along its apical/basal axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0051092", "l": "positive regulation of NF-kappaB transcription factor activity", "d": ["Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0090713", "l": "immunological memory process", "d": ["Any process of the immune system that can contribute to the formation of immunological memory or an immune response based upon activation of immunological memory."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:0044784", "l": "metaphase/anaphase transition of cell cycle", "d": ["The cell cycle process in which a cell progresses from metaphase to anaphase as part of the cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044602", "l": "protein deadenylylation", "d": ["The removal of an adenylyl group (adenosine 5'-monophosphate; AMP) from a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0072576", "l": "liver morphogenesis", "d": ["The process in which the anatomical structures of the liver are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018007", "l": "N-terminal peptidyl-glycine N-glucuronylation", "d": ["The glucuronylation of the N-terminal glycine of proteins to form the derivative D-glucuronyl-N-glycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990832", "l": "slow axonal transport", "d": ["The directed slow movement of non-membranous molecules in nerve cell axons. It is comprised of a Slow Component a (SCa) and a Slow Component b (SCb) which differ in transport rates and protein composition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032927", "l": "positive regulation of activin receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072713", "l": "cellular response to thiabendazole", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071529", "l": "cementum mineralization", "d": ["The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited into the initial acellular cementum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046342", "l": "CDP-diacylglycerol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035762", "l": "dorsal motor nucleus of vagus nerve morphogenesis", "d": ["The process in which the dorsal motor nucleus of the vagus nerve is generated and organized. Morphogenesis pertains to the creation of form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010406", "l": "classical arabinogalactan protein metabolic process", "d": ["The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein containing Hyp, Ala, Ser, Thr and Gly as the major amino acid constituents, and the C-terminus is GPI anchored."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0032105", "l": "negative regulation of response to extracellular stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an extracellular stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0017007", "l": "protein-bilin linkage", "d": ["The covalent linkage of bilin and a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071346", "l": "cellular response to type II interferon", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0070787", "l": "conidiophore development", "d": ["The process whose specific outcome is the progression of the conidiophore over time, from its formation to the mature structure. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006117", "l": "acetaldehyde metabolic process", "d": ["The chemical reactions and pathways involving acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0043303", "l": "mast cell degranulation", "d": ["The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901132", "l": "kanamycin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of kanamycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904707", "l": "positive regulation of vascular associated smooth muscle cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905293", "l": "negative regulation of neural crest cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0014902", "l": "myotube differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0003188", "l": "heart valve formation", "d": ["The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035994", "l": "response to muscle stretch", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a myofibril being extended beyond its slack length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002021", "l": "response to dietary excess", "d": ["The physiological process in which dietary excess is sensed by the central nervous system, resulting in a reduction in food intake and increased energy expenditure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042796", "l": "snRNA transcription by RNA polymerase III", "d": ["The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904438", "l": "regulation of iron ion import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of iron ions import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098994", "l": "disruption of host cell envelope during viral entry", "d": ["The disruption of host cell envelope by viral proteins during virus entry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:0043255", "l": "regulation of carbohydrate biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0014719", "l": "skeletal muscle satellite cell activation", "d": ["The change of a skeletal muscle satellite cell from a mitotically quiescent to a mitotically active state following exposure to some activating factor such as a cellular or soluble ligand. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010877", "l": "lipid transport involved in lipid storage", "d": ["The directed movement of lipids into cells that is part of their accumulation and maintenance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061553", "l": "ganglion maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021844", "l": "interneuron sorting involved in substrate-independent cerebral cortex tangential migration", "d": ["The establishment and response to guidance cues that distribute interneurons to different cerebral cortex structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060683", "l": "regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling", "d": ["Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the epithelial cells to the mesenchymal cells of the salivary gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010345", "l": "suberin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of suberin monomers and suberin polyesters. Suberin monomers are derived from fatty acids and trans-cinnamic acids. The monomers are then cross-linked with glycerols."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032930", "l": "positive regulation of superoxide anion generation", "d": ["Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0061085", "l": "regulation of histone H3-K27 methylation", "d": ["Any process that modulates the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010071", "l": "root meristem specification", "d": ["The specification of a meristem which will give rise to a primary or lateral root."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903970", "l": "negative regulation of response to macrophage colony-stimulating factor", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to macrophage colony-stimulating factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0002883", "l": "regulation of hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of hypersensitivity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:2000095", "l": "regulation of Wnt signaling pathway, planar cell polarity pathway", "d": ["Any process that modulates the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001036", "l": "negative regulation of tongue muscle cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051767", "l": "nitric-oxide synthase biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nitric-oxide synthase, an enzyme which catalyzes the reaction L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990671", "l": "vesicle fusion with Golgi medial cisterna membrane", "d": ["The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi medial cisterna. This can involve anterograde or retrograde transport vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000930", "l": "regulation of cellobiose metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellobiose metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072122", "l": "extraglomerular mesangial cell proliferation", "d": ["The multiplication or reproduction of extraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001186", "l": "negative regulation of CD8-positive, alpha-beta T cell activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002523", "l": "leukocyte migration involved in inflammatory response", "d": ["The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003054", "l": "circadian regulation of systemic arterial blood pressure by the suprachiasmatic nucleus", "d": ["The process in which the suprachiasmatic nucleus modulates blood pressure at different values with a regularity of approximately 24 hours."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905090", "l": "negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010792", "l": "DNA double-strand break processing involved in repair via single-strand annealing", "d": ["The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via single-strand annealing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003301", "l": "physiological cardiac muscle hypertrophy", "d": ["The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905554", "l": "negative regulation of vessel branching", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002600", "l": "positive regulation of antigen processing and presentation of lipid antigen via MHC class Ib", "d": ["Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018285", "l": "iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide", "d": ["The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000075", "l": "negative regulation of cytokinesis, site selection", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of site selection that occurs as part of cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0001738", "l": "morphogenesis of a polarized epithelium", "d": ["The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000566", "l": "positive regulation of CD8-positive, alpha-beta T cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006176", "l": "dATP biosynthetic process from ADP", "d": ["The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate) from other compounds, including ADP, adenosine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039521", "l": "suppression by virus of host autophagy", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of autophagy in the host."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035509", "l": "negative regulation of myosin-light-chain-phosphatase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of myosin-light-chain-phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:1905933", "l": "regulation of cell fate determination", "d": ["Any process that modulates the frequency, rate or extent of cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.656143477476277", "identifiers": [{"i": "GO:0042110", "l": "T cell activation", "d": ["The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022022", "l": "septal cell proliferation", "d": ["The multiplication or reproduction of septal cells, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006655", "l": "phosphatidylglycerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035341", "l": "regulation of inosine transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070257", "l": "positive regulation of mucus secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097271", "l": "protein localization to bud neck", "d": ["A process in which a protein is transported to, or maintained at, a location within a cellular bud neck."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032744", "l": "positive regulation of interleukin-20 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-20 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050984", "l": "peptidyl-serine sulfation", "d": ["The sulfation of peptidyl-serine to form peptidyl-O-sulfo-L-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901356", "l": "beta-D-galactofuranose metabolic process", "d": ["The chemical reactions and pathways involving beta-D-galactofuranose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003347", "l": "epicardial cell to mesenchymal cell transition", "d": ["A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. The epicardium is a part of the pericardium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901858", "l": "regulation of mitochondrial DNA metabolic process", "d": ["Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060032", "l": "notochord regression", "d": ["The developmental process in which the stucture of the notochord is destroyed in an embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902061", "l": "betaine aldehyde metabolic process", "d": ["The chemical reactions and pathways involving betaine aldehyde."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061243", "l": "mesonephric renal vesicle morphogenesis", "d": ["The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045722", "l": "positive regulation of gluconeogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of gluconeogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0030278", "l": "regulation of ossification", "d": ["Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.744066580938323", "identifiers": [{"i": "GO:1990151", "l": "protein localization to cell tip", "d": ["A process in which a protein is transported to, or maintained in, a location at the cell tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036113", "l": "very long-chain fatty-acyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019517", "l": "L-threonine catabolic process to D-lactate", "d": ["The chemical reactions and pathways resulting in the breakdown of L- threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound methylglyoxal, which is subsequently converted to D-lactate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1904105", "l": "positive regulation of convergent extension involved in gastrulation", "d": ["Any process that activates or increases the frequency, rate or extent of convergent extension involved in gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042940", "l": "D-amino acid transport", "d": ["The directed movement of the D-enantiomer of an amino acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070755", "l": "negative regulation of interleukin-35 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-35 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0060425", "l": "lung morphogenesis", "d": ["The process in which the anatomical structures of the lung are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010286", "l": "heat acclimation", "d": ["Any process that increases heat tolerance of an organism in response to high temperatures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090312", "l": "positive regulation of protein deacetylation", "d": ["Any process that increases the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902857", "l": "positive regulation of non-motile cilium assembly", "d": ["Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0034486", "l": "vacuolar transmembrane transport", "d": ["The process in which a solute is transported from one side of the vacuolar membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0001745", "l": "compound eye morphogenesis", "d": ["The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060586", "l": "multicellular organismal-level iron ion homeostasis", "d": ["A chemical homeostatic process involved in the maintenance of a steady state level of iron within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.062476272212777", "identifiers": [{"i": "GO:0014706", "l": "striated muscle tissue development", "d": ["The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000897", "l": "amylopectin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an amylopectin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0018414", "l": "nickel incorporation into metallo-sulfur cluster", "d": ["The incorporation of nickel into a metallo-sulfur cluster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019345", "l": "cysteine biosynthetic process via S-sulfo-L-cysteine", "d": ["The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate S-sulfo-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072309", "l": "mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis", "d": ["The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0072158", "l": "proximal tubule morphogenesis", "d": ["The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000098", "l": "negative regulation of smooth muscle cell-matrix adhesion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell-matrix adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990109", "l": "rejection of pollen from other species", "d": ["The recognition and rejection of pollen of one species by cells in the stigma of another species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048105", "l": "establishment of body hair planar orientation", "d": ["Orientation of body hairs, projections from the surface of an organism, such that the hairs all point in a uniform direction along the surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0050728", "l": "negative regulation of inflammatory response", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001112", "l": "DNA-templated transcription open complex formation", "d": ["Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048089", "l": "regulation of female pigmentation", "d": ["Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in females."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099093", "l": "calcium export from the mitochondrion", "d": ["A process in which a calcium ion (Ca2+) is transported out of the mitochondrial matrix, and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032748", "l": "positive regulation of interleukin-24 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-24 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904039", "l": "negative regulation of iron export across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000424", "l": "positive regulation of eosinophil chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of eosinophil chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902374", "l": "regulation of rRNA catabolic process", "d": ["Any process that modulates the frequency, rate or extent of rRNA catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903574", "l": "negative regulation of cellular response to amino acid starvation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a cellular response to amino acid starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0051090", "l": "regulation of DNA-binding transcription factor activity", "d": ["Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060016", "l": "granulosa cell development", "d": ["The process whose specific outcome is the progression of a granulosa cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a granulosa cell fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090044", "l": "positive regulation of tubulin deacetylation", "d": ["Any process that increases the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "51.953372645748793", "identifiers": [{"i": "GO:0051707", "l": "response to other organism", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021555", "l": "midbrain-hindbrain boundary morphogenesis", "d": ["The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141031", "l": "perturbation by symbiont of host actin cytoskeleton via actin crosslinking", "d": ["The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by actin crosslinking the host actin filaments. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0055071", "l": "manganese ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of manganese ions within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0110018", "l": "cap-independent translational initiation of circular RNA", "d": ["The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate circRNA translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0098904", "l": "regulation of AV node cell action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110042", "l": "negative regulation of pharynx morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of pharynx morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060705", "l": "neuron differentiation involved in salivary gland development", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048033", "l": "heme O metabolic process", "d": ["The chemical reactions and pathways involving heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061921", "l": "peptidyl-lysine propionylation", "d": ["The propionylation of peptidyl-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1904814", "l": "regulation of protein localization to chromosome, telomeric region", "d": ["Any process that modulates the frequency, rate or extent of protein localization to chromosome, telomeric region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003189", "l": "aortic valve formation", "d": ["The developmental process pertaining to the initial formation of the aortic valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034375", "l": "high-density lipoprotein particle remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0120256", "l": "olefinic compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900961", "l": "positive regulation of 17-methylnonadec-1-ene metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061457", "l": "mesonephric cell migration involved in male gonad development", "d": ["The orderly movement of a cell from the mesonephros to the male gonad, contributing to its development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0048546", "l": "digestive tract morphogenesis", "d": ["The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0039007", "l": "pronephric nephron morphogenesis", "d": ["The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042631", "l": "cellular response to water deprivation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071392", "l": "cellular response to estradiol stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045979", "l": "positive regulation of nucleoside metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072196", "l": "proximal/distal pattern formation involved in pronephric nephron development", "d": ["The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of the pronephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.777964009505382", "identifiers": [{"i": "GO:0019236", "l": "response to pheromone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090269", "l": "fibroblast growth factor production", "d": ["The appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019455", "l": "L-cysteine catabolic process via cystine, using cystine reductase", "d": ["The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cystine reductase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071539", "l": "protein localization to centrosome", "d": ["A process in which a protein is transported to, or maintained at, the centrosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030839", "l": "regulation of intermediate filament polymerization", "d": ["Any process that modulates the frequency, rate or extent of the assembly of intermediate filaments by the addition of monomers to a filament."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0016145", "l": "S-glycoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060278", "l": "regulation of ovulation", "d": ["Any process that modulates the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.499776466209866", "identifiers": [{"i": "GO:0060341", "l": "regulation of cellular localization", "d": ["Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009663", "l": "plasmodesma organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasmodesma, a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001246", "l": "negative regulation of phosphatidylcholine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099139", "l": "cheating during chimeric sorocarp development", "d": ["Any process during chimeric sorocarp development that increases by which a cell increases the number of spore cells sharing its genotype at the expense of cells of other genotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0007316", "l": "pole plasm RNA localization", "d": ["Any process in which RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070308", "l": "lens fiber cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0086013", "l": "membrane repolarization during cardiac muscle cell action potential", "d": ["The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990708", "l": "conditioned place preference", "d": ["The associative learning process by which an animal learns and remembers an association between a neutral, unchanging environment and a putatively rewarding, internal state produced by a xenobiotic or drug."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046064", "l": "dCMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dCMP, deoxycytidine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106148", "l": "4-hydroxyindole-3- carbonyl nitrile biosynthesis", "d": ["The chemical reactions and pathways resulting in the formation of 4-hydroxyindole-3- carbonyl nitrile (4-OH-ICN), a cyanogenic glucoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002463", "l": "central tolerance induction to nonself antigen", "d": ["Tolerance induction to nonself antigens in the central lymphoid organs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032244", "l": "positive regulation of nucleoside transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002596", "l": "negative regulation of antigen processing and presentation of peptide antigen via MHC class Ib", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0016046", "l": "detection of fungus", "d": ["The series of events in which a stimulus from a fungus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0070597", "l": "cell wall (1->3)-alpha-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0045639", "l": "positive regulation of myeloid cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.071082486141265", "identifiers": [{"i": "GO:0032835", "l": "glomerulus development", "d": ["The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0002369", "l": "T cell cytokine production", "d": ["Any process that contributes to cytokine production by a T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1901464", "l": "negative regulation of tetrapyrrole biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097332", "l": "response to antipsychotic drug", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902136", "l": "(-)-secoisolariciresinol metabolic process", "d": ["The chemical reactions and pathways involving (-)-secoisolariciresinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039711", "l": "cytoplasmic helical capsid assembly", "d": ["The assembly of a helical viral capsid in the cytoplasm. Occurs by assembling around the viral genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "51.916125143191451", "identifiers": [{"i": "GO:0002252", "l": "immune effector process", "d": ["Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021526", "l": "medial motor column neuron differentiation", "d": ["The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of medial motor column neurons. Medial motor column neurons are generated at all rostrocaudal levels and send axons to the axial muscles (medial group) and to the body wall muscles (lateral group). Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001915", "l": "negative regulation of T cell mediated cytotoxicity", "d": ["Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900800", "l": "cspyrone B1 metabolic process", "d": ["The chemical reactions and pathways involving cspyrone B1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0033327", "l": "Leydig cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061279", "l": "epithelial cell migration involved in mesonephric distal tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902785", "l": "cellular response to undecane", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061364", "l": "apoptotic process involved in luteolysis", "d": ["The apoptotic process that contributes to luteolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007004", "l": "telomere maintenance via telomerase", "d": ["The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034640", "l": "establishment of mitochondrion localization by microtubule attachment", "d": ["The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900282", "l": "regulation of cellobiose catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellobiose catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904059", "l": "regulation of locomotor rhythm", "d": ["Any process that modulates the frequency, rate or extent of locomotor rhythm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902607", "l": "negative regulation of large conductance calcium-activated potassium channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of large conductance calcium-activated potassium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901177", "l": "lycopene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lycopene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033312", "l": "chlorophyll a biosynthetic process via geranylgeranyl-chlorophyll a", "d": ["The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate geranylgeranyl-chlorophyll a."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007542", "l": "primary sex determination, germ-line", "d": ["The transmission of information about sexual status, from the initial general determination, to signals specific to the germ-line."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014912", "l": "negative regulation of smooth muscle cell migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002857", "l": "positive regulation of natural killer cell mediated immune response to tumor cell", "d": ["Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "46.074388257820353", "identifiers": [{"i": "GO:0023061", "l": "signal release", "d": ["The process in which a signal is secreted or discharged into the extracellular medium from a cellular source."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021939", "l": "extracellular matrix-granule cell signaling involved in regulation of granule cell precursor proliferation", "d": ["The process that mediates the transfer of information from the extracellular matrix to granule cell precursors resulting in a decrease in rate of granule cell precursor cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070054", "l": "mRNA splicing, via endonucleolytic cleavage and ligation", "d": ["Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0042130", "l": "negative regulation of T cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904282", "l": "regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I", "d": ["Any process that modulates the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903434", "l": "negative regulation of constitutive secretory pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of constitutive secretory pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046228", "l": "2,4,5-trichlorophenoxyacetic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0000707", "l": "meiotic DNA recombinase assembly", "d": ["During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051945", "l": "negative regulation of catecholamine uptake involved in synaptic transmission", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061436", "l": "establishment of skin barrier", "d": ["Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075264", "l": "regulation of oogonium development", "d": ["Any process that modulates the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061148", "l": "extracellular matrix organization involved in endocardium development", "d": ["A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001042", "l": "negative regulation of septum digestion after cytokinesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0070633", "l": "transepithelial transport", "d": ["The directed movement of a substance from one side of an epithelium to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903556", "l": "negative regulation of tumor necrosis factor superfamily cytokine production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor superfamily cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046061", "l": "dATP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001985", "l": "negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction as a result of the baroreceptor response to increased blood pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:1902480", "l": "protein localization to mitotic spindle", "d": ["A process in which a protein is transported to, or maintained in, a location within a mitotic spindle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0071362", "l": "cellular response to ether", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904451", "l": "regulation of potassium:proton exchanging ATPase activity", "d": ["Any process that modulates the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905364", "l": "regulation of endosomal vesicle fusion", "d": ["Any process that modulates the frequency, rate or extent of endosomal vesicle fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048624", "l": "plantlet formation on parent plant", "d": ["The process in which a new plantlet develops from a meristem on the plant body. As part of this process, when the plantlet is large enough to live independently, the physical connection between the new plantlet and the main plant is severed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019246", "l": "L(+)-lactate biosynthetic process from pyruvate", "d": ["The chemical reactions and pathways resulting in the formation of L(+)-lactate from other compounds, including pyruvate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0098732", "l": "macromolecule deacylation", "d": ["The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a macromolecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000615", "l": "regulation of histone H3-K9 acetylation", "d": ["Any process that modulates the frequency, rate or extent of histone H3-K9 acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0060713", "l": "labyrinthine layer morphogenesis", "d": ["The process in which the labyrinthine layer of the placenta is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901331", "l": "positive regulation of odontoblast differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of odontoblast differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:1901993", "l": "regulation of meiotic cell cycle phase transition", "d": ["Any process that modulates the frequency, rate or extent of meiotic cell cycle phase transition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034402", "l": "recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex", "d": ["The process in which proteins required for 3'-end transcript processing become associated with the RNA polymerase II holoenzyme complex and the 3' end of a transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905256", "l": "negative regulation of RNA binding transcription factor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding transcription factor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0030103", "l": "vasopressin secretion", "d": ["The regulated release of vasopressin from secretory granules into the blood."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044206", "l": "UMP salvage", "d": ["Any process which produces UMP, uridine monophosphate, from derivatives of it (e.g. cytidine, uridine, cytosine) without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071722", "l": "detoxification of arsenic-containing substance", "d": ["Any process that reduces or removes the toxicity of compounds containing arsenic, including arsenates, arsenites, and arsenides. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of arsenic or arsenic-containing compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0050482", "l": "arachidonic acid secretion", "d": ["The controlled release of arachidonic acid from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0043129", "l": "surfactant homeostasis", "d": ["Any process involved in the maintenance of a steady-state level of a surface-active agent that maintains the surface tension of a liquid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039648", "l": "modulation by symbiont of host protein ubiquitination", "d": ["Any process by which a symbiont increases or decreases ubiquitination of target proteins of a host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1905169", "l": "regulation of protein localization to phagocytic vesicle", "d": ["Any process that modulates the frequency, rate or extent of protein localization to phagocytic vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030259", "l": "lipid glycosylation", "d": ["Covalent attachment of a glycosyl residue to a lipid molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098881", "l": "exocytic insertion of neurotransmitter receptor to plasma membrane", "d": ["The exocytic fusion of neurotransmitter receptor-containing vesicles with plasma membrane, resulting in the integration of neurotransmitter receptors into the plasma membrane. This process includes tethering and docking steps that prepare vesicles for fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110031", "l": "negative regulation of G2/MI transition of meiotic cell cycle", "d": ["Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:1904746", "l": "negative regulation of apoptotic process involved in development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902528", "l": "regulation of protein linear polyubiquitination", "d": ["Any process that modulates the frequency, rate or extent of protein linear polyubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000502", "l": "negative regulation of natural killer cell chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of natural killer cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106097", "l": "cellular response to ceramide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0007099", "l": "centriole replication", "d": ["The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0015744", "l": "succinate transport", "d": ["The directed movement of succinate, the dianion of ethane dicarboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140215", "l": "regulation of D-aspartate import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061580", "l": "colon epithelial cell migration", "d": ["The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002788", "l": "regulation of antifungal peptide production", "d": ["Any process that modulates the frequency, rate, or extent of antifungal peptide production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001182", "l": "RNA polymerase I promoter clearance", "d": ["A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase I, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.474657494018913", "identifiers": [{"i": "GO:0007530", "l": "sex determination", "d": ["Any process that establishes and transmits the specification of sexual status of an individual organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.905555711669919", "identifiers": [{"i": "GO:0006302", "l": "double-strand break repair", "d": ["The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0006558", "l": "L-phenylalanine metabolic process", "d": ["The chemical reactions and pathways involving L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902018", "l": "negative regulation of cilium assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071373", "l": "cellular response to luteinizing hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0047484", "l": "regulation of response to osmotic stress", "d": ["Any process that modulates the rate or extent of the response to osmotic stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0003413", "l": "chondrocyte differentiation involved in endochondral bone morphogenesis", "d": ["The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990402", "l": "embryonic liver development", "d": ["The process occurring during the embryonic phase whose specific outcome is the progression of the liver over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0000730", "l": "DNA recombinase assembly", "d": ["The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0051480", "l": "regulation of cytosolic calcium ion concentration", "d": ["Any process involved in the maintenance of an internal steady state of calcium ions within the cytosol of a cell or between the cytosol and its surroundings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903292", "l": "protein localization to Golgi membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within a Golgi membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007280", "l": "pole cell migration", "d": ["The directed movement of a pole cell (germline progenitors in insects) from its site of production at the posterior pole of the embryo through to the site where the gonads will form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900796", "l": "terrequinone A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of terrequinone A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0098933", "l": "disruption by symbiont of host cell envelope", "d": ["The process by which a symbiont breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009177", "l": "pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0072176", "l": "nephric duct development", "d": ["The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.654207985252562", "identifiers": [{"i": "GO:0046942", "l": "carboxylic acid transport", "d": ["The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051460", "l": "negative regulation of corticotropin secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropic hormone from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.850028330009977", "identifiers": [{"i": "GO:0009165", "l": "nucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0030811", "l": "regulation of nucleotide catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070729", "l": "cyclic nucleotide transport", "d": ["The directed movement of a cyclic nucleotide, any nucleotide in which phosphate group is in diester linkage to two positions on the sugar residue, into, out of or within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0043970", "l": "histone H3-K9 acetylation", "d": ["The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 9 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031504", "l": "peptidoglycan-based cell wall organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the peptidoglycan-based cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008362", "l": "chitin-based embryonic cuticle biosynthetic process", "d": ["Synthesis, including the chemical reactions and pathways resulting in the formation of chitin and other components, and deposition of a chitin-based embryonic cuticle by the underlying epidermal epithelium. This tough, waterproof cuticle layer is essential to provide structural integrity of the larval body. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:1902296", "l": "DNA strand elongation involved in cell cycle DNA replication", "d": ["Any DNA strand elongation that is involved in cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034672", "l": "anterior/posterior pattern specification involved in pronephros development", "d": ["The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071879", "l": "positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the adenylate cyclase-activating adrenergic receptor protein signaling pathway. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.058137015083851", "identifiers": [{"i": "GO:0009451", "l": "RNA modification", "d": ["The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032965", "l": "regulation of collagen biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901762", "l": "oxytetracycline catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of oxytetracycline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0051348", "l": "negative regulation of transferase activity", "d": ["Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0002639", "l": "positive regulation of immunoglobulin production", "d": ["Any process that activates or increases the frequency, rate, or extent of immunoglobulin production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043058", "l": "regulation of backward locomotion", "d": ["Any process that modulates the speed, mechanical force, or rhythm of the posterior movement of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003225", "l": "left ventricular trabecular myocardium morphogenesis", "d": ["The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090270", "l": "regulation of fibroblast growth factor production", "d": ["Any process that modulates the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001812", "l": "positive regulation of type I hypersensitivity", "d": ["Any process that activates or increases the frequency, rate or extent of type I hypersensitivity, a type of inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0031579", "l": "membrane raft organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane rafts, small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903342", "l": "negative regulation of meiotic DNA double-strand break formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072199", "l": "regulation of mesenchymal cell proliferation involved in ureter development", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904915", "l": "positive regulation of establishment of protein-containing complex localization to telomere", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0036124", "l": "histone H3-K9 trimethylation", "d": ["The modification of histone H3 by addition of three methyl groups to lysine at position 9 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061322", "l": "disseminated nephrocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is an insect renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043517", "l": "positive regulation of DNA damage response, signal transduction by p53 class mediator", "d": ["Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034195", "l": "L-galactonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-galactonate, the anion of L-galactonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0016525", "l": "negative regulation of angiogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061265", "l": "mesonephric nephron tubule epithelial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0003056", "l": "regulation of vascular associated smooth muscle contraction", "d": ["Any process that increases the frequency, rate or extent of vascular smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035971", "l": "peptidyl-histidine dephosphorylation", "d": ["The removal of phosphoric residues from peptidyl-O-phospho-L-histidine to form peptidyl-histidine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.841553627217166", "identifiers": [{"i": "GO:0033043", "l": "regulation of organelle organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902820", "l": "1-undecene metabolic process", "d": ["The chemical reactions and pathways involving 1-undecene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904897", "l": "regulation of hepatic stellate cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of hepatic stellate cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097392", "l": "chemokine (C-X-C motif) ligand 16 production", "d": ["The appearance of chemokine (C-X-C motif) ligand 16 (CXCL16) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042210", "l": "octamethylcyclotetrasiloxane catabolic process to dimethylsilanediol", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane into dimethylsilanediol. The former is a tetramer of the latter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904004", "l": "positive regulation of sebum secreting cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of sebum secreting cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0061140", "l": "lung secretory cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032769", "l": "negative regulation of monooxygenase activity", "d": ["Any process that stops or reduces the activity of a monooxygenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010695", "l": "regulation of mitotic spindle pole body separation", "d": ["Any process that modulates the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000590", "l": "negative regulation of metanephric mesenchymal cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of metanephric mesenchymal cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045592", "l": "regulation of cumulus cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of ovarian cumulus cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002937", "l": "tRNA 4-thiouridine biosynthesis", "d": ["The processes whereby a uridine residue in a tRNA is converted to 4-thiouridine. Typically 4-thiouridine is found at position 8, in many transfer RNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031550", "l": "positive regulation of brain-derived neurotrophic factor receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050903", "l": "leukocyte activation-dependent arrest", "d": ["The formation of an integrin-dependent strong adhesive bond between leukocytes and blood vessel endothelial cells which is dependent on prior activation of the leukocyte and leads to the firm attachment of the leukocyte to the endothelial surface, typically the third step in cellular extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905296", "l": "negative regulation of neural crest cell fate specification", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046716", "l": "muscle cell cellular homeostasis", "d": ["The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097289", "l": "alpha-ribazole metabolic process", "d": ["The chemical reactions and pathways involving alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904731", "l": "positive regulation of intestinal lipid absorption", "d": ["Any process that activates or increases the frequency, rate or extent of intestinal lipid absorption."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0062009", "l": "secondary palate development", "d": ["The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010610", "l": "regulation of mRNA stability involved in response to stress", "d": ["Any process that modulates the propensity of mRNA molecules to degradation that is part of a change in state or activity of a cell as a result of an exogenous disturbance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006430", "l": "lysyl-tRNA aminoacylation", "d": ["The process of coupling lysine to lysyl-tRNA, catalyzed by lysyl-tRNA synthetase. The lysyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a lysine-accetping tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071656", "l": "negative regulation of granulocyte colony-stimulating factor production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granulocyte colony stimulating factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009926", "l": "auxin polar transport", "d": ["The unidirectional movement of auxin in the stem from tip to base along the vector of gravity or basipetally."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002202", "l": "somatic diversification of variable lymphocyte receptors of jawless fish", "d": ["The somatic process that results in the generation of sequence diversity of the variable lymphocyte receptors (VLR) of jawless fish."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032416", "l": "negative regulation of sodium:proton antiporter activity", "d": ["Any process that stops or reduces the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900759", "l": "positive regulation of D-amino-acid oxidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of D-amino-acid oxidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042795", "l": "snRNA transcription by RNA polymerase II", "d": ["The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "51.846845898039028", "identifiers": [{"i": "GO:0016070", "l": "RNA metabolic process", "d": ["The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1990735", "l": "gamma-tubulin complex localization to mitotic spindle pole body", "d": ["Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at a mitotic spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045022", "l": "early endosome to late endosome transport", "d": ["The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905557", "l": "regulation of mitotic nuclear envelope disassembly", "d": ["Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901322", "l": "response to chloramphenicol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904051", "l": "regulation of protein targeting to vacuole involved in autophagy", "d": ["Any process that modulates the frequency, rate or extent of protein targeting to vacuole involved in autophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904568", "l": "cellular response to wortmannin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902045", "l": "negative regulation of Fas signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Fas signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042676", "l": "compound eye cone cell fate commitment", "d": ["The process in which the cone cells of the compound eye, the lens-secreting cells in the ommatidia, adopt pathways of differentiation that lead to the establishment of their distinct cell type."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055026", "l": "negative regulation of cardiac muscle tissue development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032326", "l": "Mo-molybdopterin cofactor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019658", "l": "glucose fermentation to lactate and acetate", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glucose to lactate and acetate, yielding energy in the form of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016598", "l": "protein arginylation", "d": ["The conjugation of arginine to the N-terminal aspartate or glutamate of a protein; required for the degradation of the protein via the ubiquitin pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0043711", "l": "pilus organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pilus, a short filamentous structure on a bacterial cell, flagella-like in structure and generally present in many copies."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.161881760686384", "identifiers": [{"i": "GO:0032956", "l": "regulation of actin cytoskeleton organization", "d": ["Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902280", "l": "regulation of RNA helicase activity", "d": ["Any process that modulates the frequency, rate or extent of ATP-dependent RNA helicase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009609", "l": "response to symbiotic bacterium", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0040001", "l": "establishment of mitotic spindle localization", "d": ["The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905228", "l": "positive regulation of adhesion of symbiont to host epithelial cell", "d": ["Any process that activates or increases the frequency, rate or extent of adhesion of symbiont to host epithelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904117", "l": "cellular response to vasopressin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904310", "l": "cellular response to cordycepin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006043", "l": "glucosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099052", "l": "vesicle scission involved in clathrin-mediated endocytosis", "d": ["The membrane scission process that is the final step in the formation of a clathrin-coated endocytic vesicle: separation from the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902050", "l": "neosartoricin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of neosartoricin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002848", "l": "positive regulation of T cell tolerance induction to tumor cell", "d": ["Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction to tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.437453848678771", "identifiers": [{"i": "GO:0006886", "l": "intracellular protein transport", "d": ["The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000005", "l": "negative regulation of metanephric S-shaped body morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric S-shaped body morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071940", "l": "fungal-type cell wall assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a fungal-type cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0033144", "l": "negative regulation of intracellular steroid hormone receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001272", "l": "positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis", "d": ["Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002150", "l": "hypochlorous acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hypochlorous acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990210", "l": "positive regulation by symbiont of indole acetic acid levels in host", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060927", "l": "cardiac pacemaker cell fate commitment", "d": ["The commitment of cells to pacemaker cell fates and their capacity to differentiate into pacemaker cells. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009694", "l": "jasmonic acid metabolic process", "d": ["The chemical reactions and pathways involving jasmonic acid, a fatty acid derivative with the formula (1R-(1 alpha, 2 beta(Z)))-3-oxo-2-(2-pentenyl)cyclopentaneacetic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010544", "l": "negative regulation of platelet activation", "d": ["Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002598", "l": "regulation of antigen processing and presentation of lipid antigen via MHC class Ib", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009907", "l": "response to photoperiod, red light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light photoperiod stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106061", "l": "negative regulation of exit from meiosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of exit from meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042381", "l": "hemolymph coagulation", "d": ["Any process in which factors in the hemolymph (the invertebrate equivalent of vertebrate blood and lymph) precipitate into insoluble clots in order to prevent loss of body fluid, and at the same time prevent the movement of microbes. Hemolymph coagulation is also part of the invertebrate humoral immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0016123", "l": "xanthophyll biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0043280", "l": "positive regulation of cysteine-type endopeptidase activity involved in apoptotic process", "d": ["Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002100", "l": "tRNA wobble adenosine to inosine editing", "d": ["The process in which an adenosine in position 34 of a tRNA is post-transcriptionally converted to inosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901896", "l": "positive regulation of ATPase-coupled calcium transmembrane transporter activity", "d": ["Any process that activates or increases the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0016120", "l": "carotene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of carotenes, hydrocarbon carotenoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903455", "l": "negative regulation of androst-4-ene-3,17-dione biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071344", "l": "diphosphate metabolic process", "d": ["The chemical reactions and pathways involving diphosphate, the anion or salt of diphosphoric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0036010", "l": "protein localization to endosome", "d": ["A process in which a protein is transported to, or maintained in, a location within an endosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035720", "l": "intraciliary anterograde transport", "d": ["The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070670", "l": "response to interleukin-4", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018898", "l": "2,4-dichlorobenzoate metabolic process", "d": ["The chemical reactions and pathways involving 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903947", "l": "positive regulation of ventricular cardiac muscle cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of ventricular cardiac muscle cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0016093", "l": "polyprenol metabolic process", "d": ["The chemical reactions and pathways involving polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900044", "l": "regulation of protein K63-linked ubiquitination", "d": ["Any process that modulates the frequency, rate or extent of protein K63-linked ubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.481503109560144", "identifiers": [{"i": "GO:0007420", "l": "brain development", "d": ["The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046207", "l": "trypanothione catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002587", "l": "negative regulation of antigen processing and presentation of peptide antigen via MHC class II", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0160075", "l": "non-canonical inflammasome complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a non-canonical inflammasome complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043040", "l": "tRNA aminoacylation for nonribosomal peptide biosynthetic process", "d": ["The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in nonribosomal peptide synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061122", "l": "positive regulation of positive chemotaxis to cAMP", "d": ["Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140280", "l": "negative regulation of mitotic division septum assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0045851", "l": "pH reduction", "d": ["Any process that reduces the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090650", "l": "cellular response to oxygen-glucose deprivation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903023", "l": "regulation of ascospore-type prospore membrane formation", "d": ["Any process that modulates the frequency, rate or extent of formation of an ascospore-type prospore membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903687", "l": "negative regulation of border follicle cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of border follicle cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904322", "l": "cellular response to forskolin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051107", "l": "negative regulation of DNA ligation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.871876592857262", "identifiers": [{"i": "GO:0016114", "l": "terpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903652", "l": "modulation by virus of host cytoplasmic transport", "d": ["Modulation by an infecting virus of host cytoplasmic transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006334", "l": "nucleosome assembly", "d": ["The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0006991", "l": "response to sterol depletion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000489", "l": "maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)", "d": ["Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018254", "l": "peptidyl-tyrosine adenylylation", "d": ["The adenylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-adenosine)-L-tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021727", "l": "intermediate reticular formation development", "d": ["The process whose specific outcome is the progression of the intermediate reticular formation over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905712", "l": "cellular response to phosphatidylethanolamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0061437", "l": "renal system vasculature development", "d": ["The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0035315", "l": "hair cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a hair cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901629", "l": "regulation of presynaptic membrane organization", "d": ["Any process that modulates the frequency, rate or extent of presynaptic membrane organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042425", "l": "choline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0039695", "l": "DNA-templated viral transcription", "d": ["A transcription process that uses a viral DNA as a template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048697", "l": "positive regulation of collateral sprouting in absence of injury", "d": ["Any process that activates or increases the frequency, rate or extent of collateral sprouting in the absence of injury."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0048916", "l": "posterior lateral line development", "d": ["The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048775", "l": "regulation of leucophore differentiation", "d": ["Any process that modulates the frequency, rate or extent of leucophore differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901263", "l": "positive regulation of sorocarp spore cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of sorocarp spore cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098045", "l": "virus baseplate assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a virus baseplate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905184", "l": "positive regulation of protein serine/threonine phosphatase activity", "d": ["Any process that activates or increases the frequency, rate or extent of protein serine/threonine phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1903329", "l": "regulation of iron-sulfur cluster assembly", "d": ["Any process that modulates the frequency, rate or extent of iron-sulfur cluster assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0150116", "l": "regulation of cell-substrate junction organization", "d": ["Any process that modulates the frequency, rate or extent of cell-substrate junction organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0008069", "l": "dorsal/ventral axis specification, ovarian follicular epithelium", "d": ["Polarization of the ovarian follicle cells along the dorsal/ventral axis. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033398", "l": "zeatin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903906", "l": "regulation of plasma membrane raft polarization", "d": ["Any process that modulates the frequency, rate or extent of plasma membrane raft polarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075276", "l": "regulation of telium development", "d": ["Any process that modulates the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0110156", "l": "methylguanosine-cap decapping", "d": ["Cleavage of the 5'-methylguanosine-cap of an mRNA. The methylguanosine-cap is present at the 5'-end of eukaryotic mRNAs. Decapping inactivates translation initiation and promotes 5'-to-3' decay of mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061002", "l": "negative regulation of dendritic spine morphogenesis", "d": ["Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.192826706633682", "identifiers": [{"i": "GO:0050912", "l": "detection of chemical stimulus involved in sensory perception of taste", "d": ["The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034288", "l": "detection of disaccharide stimulus", "d": ["The series of events in which a stimulus from a disaccharide is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0032242", "l": "regulation of nucleoside transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0090679", "l": "cell differentiation involved in phenotypic switching", "d": ["A cell differentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002720", "l": "positive regulation of cytokine production involved in immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009999", "l": "negative regulation of auditory receptor cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from specifying into an auditory hair cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902074", "l": "response to salt", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042199", "l": "cyanuric acid metabolic process", "d": ["The chemical reactions and pathways involving cyanuric acid, a suspected gastrointestinal or liver toxicant, and a potential degradation product of triazine herbicides, such as atrazine and simazine. It is widely used for the stabilization of available chlorine in swimming pool water and is also the starting compound for the synthesis of many organic derivatives."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0060028", "l": "convergent extension involved in axis elongation", "d": ["The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contributing to the lengthening of the axis of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0020028", "l": "endocytic hemoglobin import into cell", "d": ["The directed movement of hemoglobin into a cell by receptor-mediated endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.085121200529862", "identifiers": [{"i": "GO:0006959", "l": "humoral immune response", "d": ["An immune response mediated through a body fluid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.622337805354121", "identifiers": [{"i": "GO:1900376", "l": "regulation of secondary metabolite biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140140", "l": "mitochondrial guanine nucleotide transmembrane transport", "d": ["The process in which a guanine nucleotide is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046322", "l": "negative regulation of fatty acid oxidation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid oxidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902989", "l": "meiotic telomere maintenance via semi-conservative replication", "d": ["Any telomere maintenance via semi-conservative replication that is involved in meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0007133", "l": "meiotic anaphase I", "d": ["The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990155", "l": "Dsc E3 ubiquitin ligase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a Dsc E3 ubiquitin ligase complex, an E3 ubiquitin ligase complex localized to the ER and Golgi membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0044342", "l": "type B pancreatic cell proliferation", "d": ["The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018887", "l": "4-carboxy-4'-sulfoazobenzene metabolic process", "d": ["The chemical reactions and pathways involving 4-carboxy-4'-sulfoazobenzene, a sulfonated azo compound synthesized by nitro-amine condensation from sulfanilic acid and 4-nitrobenzoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900746", "l": "regulation of vascular endothelial growth factor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of vascular endothelial growth factor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0006566", "l": "threonine metabolic process", "d": ["The chemical reactions and pathways involving threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035635", "l": "entry of bacterium into host cell", "d": ["The process in which a bacterium enters a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019559", "l": "histidine catabolic process to imidazol-5-yl-lactate", "d": ["The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including imidazol-5-yl-lactate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990616", "l": "magnesium ion export from mitochondrion", "d": ["The directed movement of magnesium ions out of mitochondrial matrix into the cytosol by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042104", "l": "positive regulation of activated T cell proliferation", "d": ["Any process that activates or increases the rate or extent of activated T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002368", "l": "B cell cytokine production", "d": ["Any process that contributes to cytokine production by a B cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002473", "l": "non-professional antigen presenting cell antigen processing and presentation", "d": ["The process in which a non-professional antigen presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. Non-professional antigen presenting cells include all cell types but dendritic cells, B cells, T cells, monocytes, macrophages, and neutrophils."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060336", "l": "negative regulation of type II interferon-mediated signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of an interferon-gamma-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901154", "l": "paromomycin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of paromomycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097389", "l": "chemokine (C-C motif) ligand 21 production", "d": ["The appearance of chemokine (C-C motif) ligand 21 (CCL21) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.741834732726957", "identifiers": [{"i": "GO:0006820", "l": "monoatomic anion transport", "d": ["The directed movement of a monoatomic anion, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic anions (also called simple anions) are negatively charged ions consisting of exactly one atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042541", "l": "hemoglobin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043478", "l": "pigment accumulation in response to UV light", "d": ["The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to a UV light stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0052318", "l": "regulation of phytoalexin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140673", "l": "transcription elongation-coupled chromatin remodeling", "d": ["A chromatin remodeling process that reestablishes the chromatin structure following the passage of RNA polymerase II during transcription elongation, thus preventing cryptic transcription initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0033003", "l": "regulation of mast cell activation", "d": ["Any process that modulates the frequency, rate, or extent of mast cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003045", "l": "regulation of systemic arterial blood pressure by physical factors", "d": ["The regulation of blood pressure mediated by detection of forces within the circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.444551060876734", "identifiers": [{"i": "GO:0051223", "l": "regulation of protein transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097366", "l": "response to bronchodilator", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003282", "l": "ventricular septum intermedium development", "d": ["The progression of the ventricular septum intermedium over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900917", "l": "regulation of octadecene metabolic process", "d": ["Any process that modulates the frequency, rate or extent of octadecene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009659", "l": "leucoplast organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046706", "l": "CDP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of CDP, cytidine (5'-)diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046398", "l": "UDP-glucuronate metabolic process", "d": ["The chemical reactions and pathways involving UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905672", "l": "negative regulation of lysosome organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035905", "l": "ascending aorta development", "d": ["The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905302", "l": "negative regulation of macropinocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of macropinocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000124", "l": "regulation of endocannabinoid signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of endocannabinoid signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097156", "l": "fasciculation of motor neuron axon", "d": ["The collection of motor neuron axons into a bundle of rods, known as a fascicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904023", "l": "regulation of glucose catabolic process to lactate via pyruvate", "d": ["Any process that modulates the frequency, rate or extent of glucose catabolic process to lactate via pyruvate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061336", "l": "cell morphogenesis involved in Malpighian tubule morphogenesis", "d": ["The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905465", "l": "regulation of G-quadruplex DNA unwinding", "d": ["Any process that modulates the frequency, rate or extent of G-quadruplex DNA unwinding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0045103", "l": "intermediate filament-based process", "d": ["Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "45.152237763375567", "identifiers": [{"i": "GO:0051606", "l": "detection of stimulus", "d": ["The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021754", "l": "facial nucleus development", "d": ["The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033657", "l": "modification by symbiont of host chloroplast part", "d": ["The process in which an organism effects a change in the structure or function of a component of the host cell chloroplast. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021738", "l": "fastigial nucleus development", "d": ["The process whose specific outcome is the progression of the fastigial nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0120181", "l": "focal adhesion disassembly", "d": ["The disaggregation of a focal adhesion into its constituent components. A focal adhesion is a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also functions as a locus of signal transduction activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0052083", "l": "suppression by symbiont of host cell-mediated immune response", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030321", "l": "transepithelial chloride transport", "d": ["The directed movement of chloride ions from one side of an epithelium to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075251", "l": "uredospore formation", "d": ["The process which specific outcome is the formation of an asexual, dikaryotic, often rusty-colored spore, produced in a structure called a uredinium; mostly found in the rust fungus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060281", "l": "regulation of oocyte development", "d": ["Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036352", "l": "histone H2A-K15 ubiquitination", "d": ["The modification of histone H2A by addition of ubiquitin group at lysine 15 (H2A-K15) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K15 and K63-linked ubiquitin chains are then extended from this monoubiquitin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032223", "l": "negative regulation of synaptic transmission, cholinergic", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060095", "l": "zinc potentiation of synaptic transmission, glycinergic", "d": ["Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission in the presence of zinc. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002949", "l": "tRNA threonylcarbamoyladenosine modification", "d": ["The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0086002", "l": "cardiac muscle cell action potential involved in contraction", "d": ["An action potential that occurs in a cardiac muscle cell and is involved in its contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045583", "l": "regulation of cytotoxic T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of cytotoxic T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035283", "l": "central nervous system segmentation", "d": ["Division of the central nervous system into a series of semi-repetitive parts or segments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060290", "l": "transdifferentiation", "d": ["The conversion of a differentiated cell of one fate into a differentiated cell of another fate without first undergoing cell division or reversion to a more primitive or stem cell-like fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010093", "l": "specification of floral organ identity", "d": ["The process in which the identity of a floral organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900717", "l": "negative regulation of violaceol II biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of violaceol II biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0046552", "l": "photoreceptor cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061043", "l": "regulation of vascular wound healing", "d": ["Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046843", "l": "dorsal appendage formation", "d": ["Establishment of the dorsal filaments, elaborate specializations of the chorion that protrude from the anterior end of the egg and facilitate embryonic respiration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0003352", "l": "regulation of cilium movement", "d": ["Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904259", "l": "regulation of basement membrane assembly involved in embryonic body morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010203", "l": "response to very low fluence red light stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Very low fluence red light is defined in this case as short pulses of red light followed by darkness, providing light levels of less than 0.001 mmol/m2/sec."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990627", "l": "mitochondrial inner membrane fusion", "d": ["The membrane organization process that joins two mitochondrial inner membranes to form a single membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015717", "l": "triose phosphate transport", "d": ["The directed movement of triose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904880", "l": "response to hydrogen sulfide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035474", "l": "selective angioblast sprouting", "d": ["The segregation of angioblasts into discrete arterial and venous vessels from one common precursor vessel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051106", "l": "positive regulation of DNA ligation", "d": ["Any process that activates or increases the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060051", "l": "negative regulation of protein glycosylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051913", "l": "regulation of synaptic plasticity by chemical substance", "d": ["The process in which a chemical substance modulates synaptic plasticity, the ability of synapses to change as circumstances require."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:0097553", "l": "calcium ion transmembrane import into cytosol", "d": ["A process in which a calcium ion is transported from one side of a membrane to the other into the cytosol by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110108", "l": "positive regulation of imaginal disc-derived wing vein specification", "d": ["Any process that activates or increases the frequency, rate or extent of imaginal disc-derived wing vein specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051211", "l": "anisotropic cell growth", "d": ["The process in which a cell irreversibly increases in size in one or more axes, where the growth rate varies according to the direction of growth. Growth may be limited to a particular axis, axes, or to particular locations on the surface of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0090184", "l": "positive regulation of kidney development", "d": ["Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046670", "l": "positive regulation of retinal cell programmed cell death", "d": ["Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090018", "l": "posterior neural plate formation", "d": ["The formation of posterior end of the flat, thickened layer of ectodermal cells known as the neural plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035774", "l": "positive regulation of insulin secretion involved in cellular response to glucose stimulus", "d": ["Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045343", "l": "regulation of MHC class I biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072099", "l": "anterior/posterior pattern specification involved in ureteric bud development", "d": ["The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035377", "l": "transepithelial water transport", "d": ["The directed movement of water (H2O) from one side of an epithelium to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031655", "l": "negative regulation of heat dissipation", "d": ["Any process that stops, prevents, or reduces the rate or extent of heat dissipation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030632", "l": "D-alanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-alanine, the D-enantiomer of the amino acid alanine, i.e (2R)-2-aminopropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902267", "l": "regulation of polyamine transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of polyamine transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044534", "l": "envenomation resulting in modulation of apoptotic process in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of apoptosis in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0070949", "l": "regulation of neutrophil mediated killing of symbiont cell", "d": ["Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a symbiont cell, the directed killing of a symbiont target cell by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002398", "l": "MHC class Ib protein complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000487", "l": "positive regulation of glutamine transport", "d": ["Any process that activates or increases the frequency, rate or extent of glutamine transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003304", "l": "myocardial epithelial involution involved in heart jogging", "d": ["The morphogenetic process in which the myocardium bends along a linear axis and contributes to the process of heart jogging."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000294", "l": "positive regulation of defecation", "d": ["Any process that activates or increases the frequency, rate or extent of defecation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097295", "l": "morphine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.358333567504879", "identifiers": [{"i": "GO:0044057", "l": "regulation of system process", "d": ["Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0032801", "l": "receptor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075525", "l": "viral translational termination-reinitiation", "d": ["A process which occurs as part of viral mRNA translation which allows expression of a downstream open reading frame (ORF) in a dicistronic mRNA. In this process, ribosomes translate the upstream ORF but following termination, a proportion of 40S subunits remain tethered to the mRNA and go on to re-initiate translation at the start codon of the downstream ORF."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050947", "l": "negative regulation of early stripe melanocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of early stripe melanocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1903490", "l": "positive regulation of mitotic cytokinesis", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900650", "l": "negative regulation of dehydroaustinol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dehydroaustinol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905241", "l": "positive regulation of canonical Wnt signaling pathway involved in osteoblast differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0090598", "l": "male anatomical structure morphogenesis", "d": ["The processes by which anatomical structures that are only present in the male organism are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014715", "l": "myoblast fate commitment in trunk", "d": ["The process taking place in the trunk whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0002862", "l": "negative regulation of inflammatory response to antigenic stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900068", "l": "negative regulation of cellular response to alkaline pH", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alkalinity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:1904823", "l": "purine nucleobase transmembrane transport", "d": ["The process in which a purine nucleobase is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031149", "l": "sorocarp stalk cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a sorocarp stalk cell, any of the cellulose-covered cells that form the stalk of a sorocarp. An example of this process is found in Dictyostelium discoideum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018937", "l": "nitroglycerin metabolic process", "d": ["The chemical reactions and pathways involving nitroglycerin, a well-known nitrate ester and an important component of dynamite and other propellants. Toxic to algae, invertebrate, and vertebrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901114", "l": "erythromycin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of erythromycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000226", "l": "regulation of pancreatic A cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060347", "l": "heart trabecula formation", "d": ["The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042689", "l": "regulation of crystal cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of crystal cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000656", "l": "regulation of apolipoprotein binding", "d": ["Any process that modulates the frequency, rate or extent of apolipoprotein binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0048665", "l": "neuron fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090649", "l": "response to oxygen-glucose deprivation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046898", "l": "response to cycloheximide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.232064878529073", "identifiers": [{"i": "GO:0015979", "l": "photosynthesis", "d": ["The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.824513090543306", "identifiers": [{"i": "GO:0006805", "l": "xenobiotic metabolic process", "d": ["The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072265", "l": "metanephric capsule morphogenesis", "d": ["The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046551", "l": "retinal cone cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell. A retinal cone cell is one of the two photoreceptor subtypes in a camera-type eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903516", "l": "regulation of single strand break repair", "d": ["Any process that modulates the frequency, rate or extent of single strand break repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009145", "l": "purine nucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901904", "l": "tyrocidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tyrocidine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900312", "l": "regulation of maltohexaose transport", "d": ["Any process that modulates the frequency, rate or extent of maltohexaose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072230", "l": "metanephric proximal straight tubule development", "d": ["The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903786", "l": "regulation of glutathione biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of glutathione biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045842", "l": "positive regulation of mitotic metaphase/anaphase transition", "d": ["Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0086017", "l": "Purkinje myocyte action potential", "d": ["An action potential that occurs in a Purkinje myocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021531", "l": "spinal cord radial glial cell differentiation", "d": ["The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902858", "l": "propionyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving propionyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0044111", "l": "formation of structure involved in a symbiotic process", "d": ["The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035231", "l": "cytoneme assembly", "d": ["Formation of a cytoneme, a long, thin and polarized actin-based cytoplasmic extension that projects from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050799", "l": "cocaine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0044381", "l": "glucose import in response to insulin stimulus", "d": ["The directed movement of the hexose monosaccharide glucose into a cell as a result of an insulin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0003072", "l": "renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "d": ["The renal process that modulates the force with which blood travels through the circulatory system, by impeding blood flow through the peripheral vasculature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044076", "l": "positive regulation by symbiont of host vacuole organization", "d": ["The process in which a symbiont organism activates or increases the frequency, rate or extent of vacuole organization in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0015820", "l": "leucine transport", "d": ["The directed movement of leucine, 2-amino-4-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000241", "l": "diakinesis", "d": ["The cell cycle phase which follows diplotene during prophase I of meiosis, the separation of homologous chromosomes is complete and crossing over has occurred."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0061986", "l": "negative regulation of transcription by glucose", "d": ["Any process involving glucose that decreases the frequency, rate or extent or transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905511", "l": "positive regulation of myosin II filament assembly", "d": ["Any process that activates or increases the frequency, rate or extent of myosin II filament assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070208", "l": "protein heterotrimerization", "d": ["The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0007562", "l": "eclosion", "d": ["The emergence of an adult insect from a pupa case."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052838", "l": "thiazole metabolic process", "d": ["The chemical reactions and pathways involving thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061267", "l": "mesonephric interstitial fibroblast development", "d": ["The process whose specific outcome is the progression of a mesonephric interstitial fibroblast over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0099136", "l": "chimeric non-reproductive fruiting body development", "d": ["Development of a non-reproductive fruiting body formed by aggregation of cells with different genotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002359", "l": "B-1 B cell proliferation", "d": ["The expansion of a B-1 B cell by cell division. Follows B cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0046504", "l": "glycerol ether biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033541", "l": "fatty acid beta-oxidation, unsaturated, odd number", "d": ["A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on odd-numbered carbons are degraded. In this pathway, a cis-3-enoyl-CoA is generated by the core beta-oxidation pathway, and then converted to a trans-2-enoyl-CoA, which can return to the core beta-oxidation pathway for complete degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044350", "l": "micropinocytosis", "d": ["An endocytosis process that results in the uptake of liquid material by cells from their external environment by invagination of the plasma membrane to form uncoated micropinosomes, differentiated from macropinosomes by their smaller size, on average 95 nm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905497", "l": "negative regulation of triplex DNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of triplex DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905045", "l": "negative regulation of Schwann cell proliferation involved in axon regeneration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900757", "l": "regulation of D-amino-acid oxidase activity", "d": ["Any process that modulates the frequency, rate or extent of D-amino-acid oxidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018096", "l": "peptide cross-linking via S-(2-aminovinyl)-D-cysteine", "d": ["The synthesis of (S,Z)-S-(2-aminovinyl)cysteine forming an intra-polypeptide cross-link between serine and cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046328", "l": "regulation of JNK cascade", "d": ["Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0015975", "l": "energy derivation by oxidation of reduced inorganic compounds", "d": ["The chemical reactions and pathways by which a cell derives energy from inorganic compounds; results in the oxidation of the compounds from which energy is released."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001008", "l": "positive regulation of cellulose biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellulose biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030210", "l": "heparin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140066", "l": "peptidyl-lysine crotonylation", "d": ["The crotonylation of a lysine residue in a protein. Crotonyl is the univalent radical CH3-CH=CH-CO- derived from crotonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019375", "l": "galactolipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035052", "l": "dorsal vessel aortic cell fate commitment", "d": ["The commitment of dorsal vessel cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010046", "l": "response to mycotoxin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0036444", "l": "calcium import into the mitochondrion", "d": ["A process in which a calcium ion (Ca2+) is transported from the cytosol into the mitochondrial matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0050654", "l": "chondroitin sulfate proteoglycan metabolic process", "d": ["The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905068", "l": "positive regulation of canonical Wnt signaling pathway involved in heart development", "d": ["Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904369", "l": "positive regulation of sclerenchyma cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of sclerenchyma cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090356", "l": "negative regulation of auxin metabolic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035080", "l": "heat shock-mediated polytene chromosome puffing", "d": ["The decondensing (loosening) and swelling of the chromosomal sites of heat shock genes on polytene chromosomes in response to a heat shock stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000920", "l": "positive regulation of glucuronoarabinoxylan catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of glucuronoarabinoxylan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002896", "l": "negative regulation of central B cell tolerance induction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902278", "l": "positive regulation of pancreatic amylase secretion", "d": ["Any process that activates or increases the frequency, rate or extent of pancreatic amylase secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0120127", "l": "response to zinc ion starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of zinc ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009704", "l": "de-etiolation", "d": ["The greening response of plants grown in the dark (etiolated) as a result of chloroplast biogenesis and the accumulation of chlorophyll."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902524", "l": "positive regulation of protein K48-linked ubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein K48-linked ubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904347", "l": "regulation of small intestine smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097317", "l": "invasive growth in response to biotic stimulus", "d": ["The growth of colonies in filamentous chains of cells as a result of a biotic stimulus. An example of this is Candida albicans forming invasive filaments in agar medium in response to a serum stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072729", "l": "cellular response to Gentian violet", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904496", "l": "positive regulation of substance P secretion, neurotransmission", "d": ["Any process that activates or increases the frequency, rate or extent of substance P secretion, neurotransmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045686", "l": "negative regulation of glial cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:1901502", "l": "ether catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ether."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902077", "l": "negative regulation of lateral motor column neuron migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lateral motor column neuron migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:1903306", "l": "negative regulation of regulated secretory pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032663", "l": "regulation of interleukin-2 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-2 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071925", "l": "thymic stromal lymphopoietin production", "d": ["The appearance of thymic stromal lymphopoietin (TSLP) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901315", "l": "negative regulation of histone H2A K63-linked ubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A K63-linked ubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0019083", "l": "viral transcription", "d": ["The process by which a viral genome, or part of a viral genome, is transcribed within the host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901935", "l": "beta-caryophyllene metabolic process", "d": ["The chemical reactions and pathways involving beta-caryophyllene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072351", "l": "tricarboxylic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007319", "l": "negative regulation of oskar mRNA translation", "d": ["Any process that stops, prevents or reduces the rate that oskar mRNAs are effectively translated into protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034441", "l": "plasma lipoprotein particle oxidation", "d": ["The modification of a lipid or protein within a plasma lipoprotein particle by oxidation of the lipid or one or more amino acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0045491", "l": "xylan metabolic process", "d": ["The chemical reactions and pathways involving xylan, a polymer containing a beta-1,4-linked D-xylose backbone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0032456", "l": "endocytic recycling", "d": ["The directed movement of membrane-bounded vesicles from endosomes back to the plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106214", "l": "regulation of vesicle fusion with Golgi apparatus", "d": ["Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0007088", "l": "regulation of mitotic nuclear division", "d": ["Any process that modulates the frequency, rate or extent of mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0120316", "l": "sperm flagellum assembly", "d": ["The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:1902022", "l": "L-lysine transport", "d": ["The directed movement of a L-lysine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000422", "l": "regulation of eosinophil chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of eosinophil chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000066", "l": "positive regulation of cortisol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of cortisol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0002007", "l": "detection of hypoxic conditions in blood by chemoreceptor signaling", "d": ["The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061625", "l": "glycolytic process through fructose-1-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of fructose into pyruvate through a fructose-1-phosphate intermediate, with the concomitant production of ATP and NADH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0051890", "l": "regulation of cardioblast differentiation", "d": ["Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904790", "l": "regulation of shelterin complex assembly", "d": ["Any process that modulates the frequency, rate or extent of shelterin complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990485", "l": "anaerobic lactate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039691", "l": "double stranded viral RNA replication", "d": ["A viral genome replication process where the template genome is double stranded RNA (dsRNA). Genomic dsRNA is first transcribed into single-stranded (ss) mRNA, which is then replicated to ds-genomic RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0016117", "l": "carotenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033231", "l": "carbohydrate export", "d": ["The directed movement of carbohydrates out of a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140763", "l": "programmed DNA elimination by elimination of internal DNA segments", "d": ["A programmed DNA elimination mechanism in which specific sequences, namely, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the genome. This process is known to occur in ciliates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0099628", "l": "neurotransmitter receptor diffusion trapping", "d": ["The process by which diffusing neurotransmitter receptor becomes trapped in region of the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032537", "l": "host-seeking behavior", "d": ["The specific behavior of an organism that are associated with finding a host organism; may include behavioral responses to light, temperature, or chemical emanations from the prospective host."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0039636", "l": "suppression by virus of host cell wall biogenesis", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of cell wall biogenesis in the host organism. Cell wall biogenesis includes the biosynthesis of constituent macromolecules, and the assembly and arrangement of these constituent parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051386", "l": "regulation of neurotrophin TRK receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061478", "l": "response to platelet aggregation inhibitor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet aggregation inhibitor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018919", "l": "gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolic process", "d": ["The chemical reactions and pathways involving gamma-1,2,3,4,5,6-hexachlorocyclohexane (also known as Lindane), the most common form of hexachlorohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002345", "l": "peripheral B cell receptor editing", "d": ["The process that takes place mainly in germinal center B cells in which a large number of mutations are generated in the heavy chain and light chain V-region genes and their immediately surrounding introns in order to increase antibody diversity and contribute to affinity maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048848", "l": "neurohypophysis morphogenesis", "d": ["The process in which the anatomical structures of the neurohypophysis are generated and organized. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901543", "l": "negative regulation of ent-pimara-8(14),15-diene biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0043575", "l": "detection of osmotic stimulus", "d": ["The series of events in which a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903911", "l": "positive regulation of receptor clustering", "d": ["Any process that activates or increases the frequency, rate or extent of receptor clustering."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0150146", "l": "cell junction disassembly", "d": ["The disaggregation of a cell junction into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150174", "l": "negative regulation of phosphatidylcholine metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000546", "l": "positive regulation of endothelial cell chemotaxis to fibroblast growth factor", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0045860", "l": "positive regulation of protein kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of protein kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.120403206680479", "identifiers": [{"i": "GO:0048880", "l": "sensory system development", "d": ["The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045658", "l": "regulation of neutrophil differentiation", "d": ["Any process that modulates the frequency, rate or extent of neutrophil differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043636", "l": "bisphenol A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of bisphenol A, 4,4'-(propane-2,2-diyl)diphenol, a synthetic, aromatic organic compound used as a monomer in the manufacture of polycarbonate plastic and in the manufacture of epoxy resins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0046120", "l": "deoxyribonucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038041", "l": "cross-receptor inhibition within G protein-coupled receptor heterodimer", "d": ["Inhibition of one protomer of a G protein-coupled receptor (GPCR) heterodimer by the associated subunit. For example, agonist activation of one cytokine receptor can prevent activation of its associated cytokine receptor subunit."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007278", "l": "pole cell fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into a pole cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006622", "l": "protein targeting to lysosome", "d": ["The process of directing proteins towards the lysosome using signals contained within the protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903690", "l": "negative regulation of wound healing, spreading of epidermal cells", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of wound healing, spreading of epidermal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0043572", "l": "plastid fission", "d": ["The creation of two or more plastids by division of one plastid. A plastid is any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090505", "l": "epiboly involved in wound healing", "d": ["The expansion of one cell sheet over other cells involved in wound healing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071896", "l": "protein localization to adherens junction", "d": ["Any process in which a protein is transported to, and/or maintained at the adherens junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046505", "l": "sulfolipid metabolic process", "d": ["The chemical reactions and pathways involving sulfolipids, any compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902035", "l": "positive regulation of hematopoietic stem cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014063", "l": "negative regulation of serotonin secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.712091546727706", "identifiers": [{"i": "GO:0007009", "l": "plasma membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900948", "l": "negative regulation of isoprene biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of isoprene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019573", "l": "D-arabinose catabolic process to xylulose 5-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of D-arabinose to form xylulose 5-phosphate. D-arabinose is converted into D-ribulose, which is phosphorylated to ribulose-5-phosphate, which is isomerized to give D-xylulose-5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055004", "l": "atrial cardiac myofibril assembly", "d": ["The process whose specific outcome is the progression of the atrial cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903964", "l": "monounsaturated fatty acid metabolic process", "d": ["The chemical reactions and pathways involving monounsaturated fatty acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021951", "l": "chemoattraction involved in precerebellar neuron migration", "d": ["The creation and reception of signals that guide a precerebellar neuron towards their signals, where this process is involved in tangential migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032483", "l": "regulation of Rab protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of Rab protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001795", "l": "type IIb hypersensitivity", "d": ["An inflammatory response resulting in cell death or dysfunction mediated by the direct binding of antibody to cellular receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0046439", "l": "L-cysteine metabolic process", "d": ["The chemical reactions and pathways involving L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0045980", "l": "negative regulation of nucleotide metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051763", "l": "sesquiterpene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002030", "l": "inhibitory G protein-coupled receptor phosphorylation", "d": ["The process that inhibits the signaling function of a G protein-coupled receptor by addition of a phosphate group to its third intracellular loop consensus site."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903248", "l": "regulation of citrulline biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of citrulline biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.470950656012619", "identifiers": [{"i": "GO:0009617", "l": "response to bacterium", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903233", "l": "regulation of calcium ion-dependent exocytosis of neurotransmitter", "d": ["Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990384", "l": "hyaloid vascular plexus regression", "d": ["The developmental process in which the hyaloid vascular plexus is destroyed as a part of its normal progression."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035332", "l": "positive regulation of hippo signaling", "d": ["Any process that activates or increases the frequency, rate or extent of hippo signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900443", "l": "regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus", "d": ["Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072147", "l": "glomerular parietal epithelial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018304", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042722", "l": "alpha-beta T cell activation by superantigen", "d": ["The change in morphology and behavior of alpha-beta T cells resulting from exposure to a superantigen, a microbial antigen with an extremely potent activating effect on T cells that bear a specific variable region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006386", "l": "termination of RNA polymerase III transcription", "d": ["A transcription termination process that completes the production of a primary RNA polymerase II transcript. RNA polymerase III has an intrinsic ability to terminate transcription upon incorporation of at least 4 contiguous U residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090118", "l": "receptor-mediated endocytosis involved in cholesterol transport", "d": ["A receptor-mediated endocytosis process involved in intracellular cholesterol transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900729", "l": "regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903676", "l": "positive regulation of cap-dependent translational initiation", "d": ["Any process that activates or increases the frequency, rate or extent of cap-dependent translational initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071689", "l": "muscle thin filament assembly", "d": ["The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in striated muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008377", "l": "light-induced release of internally sequestered calcium ion", "d": ["The process in which the detection of light triggers the release of internally sequestered calcium ions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0021957", "l": "corticospinal tract morphogenesis", "d": ["Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048158", "l": "oogonium stage", "d": ["The stage in mammalian oogenesis when the primordial germ cell is hardly distinguishable from other cortical cells of the ovary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009114", "l": "hypoxanthine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0014828", "l": "distal stomach smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The distal stomach is composed of the lower body and antrum and develops strong peristaltic phasic contractions that increase in amplitude as they propagate toward the pylorus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1990573", "l": "potassium ion import across plasma membrane", "d": ["The directed movement of potassium ions from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002106", "l": "endonucleolytic cleaveage between SSU-rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)", "d": ["Endonucleolytic cleavages between the SSU-rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. These cleavages liberate tRNAs from the polycistronic transcript as well as separating the SSU and LSU containing transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098866", "l": "multivesicular body fusion to apical plasma membrane", "d": ["The fusion of the membrane of a multivesicular body with the apical plasma membrane, resulting in release of exosomes from the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019629", "l": "propionate catabolic process, 2-methylcitrate cycle", "d": ["The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042217", "l": "1-aminocyclopropane-1-carboxylate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061864", "l": "basement membrane constituent secretion", "d": ["The controlled release of molecules that form the basement membrane, including carbohydrates and glycoproteins by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0001700", "l": "embryonic development via the syncytial blastoderm", "d": ["The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046588", "l": "negative regulation of calcium-dependent cell-cell adhesion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-dependent cell-cell adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902802", "l": "regulation of siRNA-dependent facultative heterochromatin formation", "d": ["Any process that modulates the frequency, rate or extent of siRNA-dependent facultative heterochromatin formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900765", "l": "emericellin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of emericellin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090340", "l": "positive regulation of secretion of lysosomal enzymes", "d": ["Any process that increases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071701", "l": "regulation of MAPK export from nucleus", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a MAP kinase from the nucleus to the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902459", "l": "positive regulation of stem cell population maintenance", "d": ["Any process that activates or increases the frequency, rate or extent of stem cell population maintenance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099183", "l": "trans-synaptic signaling by BDNF, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of brain derived neurotrophic factor (BDNF), that modulates the synaptic transmission properties of the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036046", "l": "protein demalonylation", "d": ["The removal of a malonyl group (CO-CH2-CO), from an amino acid residue within a protein or peptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010219", "l": "regulation of vernalization response", "d": ["Any process that modulates the frequency, rate or extent of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018219", "l": "peptidyl-cysteine S-acetylation", "d": ["The acetylation of peptidyl-cysteine to form peptidyl-S-acetyl-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106117", "l": "acidocalcisome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an acidocalcisome. An acidocalcisome is an electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050845", "l": "teichuronic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035823", "l": "short tract gene conversion", "d": ["A gene conversion process in which a segment of about 50-200 base pairs is transferred from the donor to the acceptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0006059", "l": "hexitol metabolic process", "d": ["The chemical reactions and pathways involving hexitols, any alditol with a chain of six carbon atoms in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070817", "l": "P-TEFb-cap methyltransferase complex localization", "d": ["Any process in which the P-TEFb-cap methyltransferase complex is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032698", "l": "negative regulation of interleukin-15 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-15 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905581", "l": "positive regulation of low-density lipoprotein particle clearance", "d": ["Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle clearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061679", "l": "Entner-Doudoroff pathway through gluconate", "d": ["The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060321", "l": "acceptance of pollen", "d": ["The recognition and acceptance of pollen by cells in the stigma, mediated by the sharing and interaction of the single locus incompatibility haplotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0030850", "l": "prostate gland development", "d": ["The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051867", "l": "general adaptation syndrome, behavioral process", "d": ["The set of behavioral processes that occur as part of the general adaptation syndrome, the response of the body to a strong, stressful stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0050925", "l": "negative regulation of negative chemotaxis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043580", "l": "periplasmic space organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the periplasmic space, the region between the inner (cytoplasmic) and outer membrane in Gram-negative bacteria, or the inner membrane and cell wall in fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061302", "l": "smooth muscle cell-matrix adhesion", "d": ["The binding of a smooth muscle cell to the extracellular matrix via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140676", "l": "oscillatory cAMP signaling", "d": ["Fluctuation in the extracellular cAMP levels due to the alternate activation of adenylate cyclase, which produces cAMP, and phosphodiesterase, which degrades it. Occurs in Dictyostelium during early sorocarp development. Oscillation in signaling result is directional chemotaxis of cells towards the center of the aggregate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046900", "l": "tetrahydrofolylpolyglutamate metabolic process", "d": ["The chemical reactions and pathways involving tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000871", "l": "negative regulation of progesterone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of progesterone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070541", "l": "response to platinum ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902786", "l": "response to dodecane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070243", "l": "regulation of thymocyte apoptotic process", "d": ["Any process that modulates the occurrence or rate of thymocyte death by apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0042596", "l": "fear response", "d": ["The response of an organism to a perceived external threat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048252", "l": "lauric acid metabolic process", "d": ["The chemical reactions and pathways involving lauric acid, a fatty acid with the formula CH3(CH2)10COOH. Derived from vegetable sources."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071411", "l": "cellular response to fluoxetine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007516", "l": "hemocyte development", "d": ["The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021664", "l": "rhombomere 5 morphogenesis", "d": ["The process in which the anatomical structures of rhombomere 5 are generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902611", "l": "cellular response to N-phenylthiourea", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0048733", "l": "sebaceous gland development", "d": ["The process whose specific outcome is the progression of the sebaceous gland over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061244", "l": "mesonephric S-shaped body morphogenesis", "d": ["The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903724", "l": "positive regulation of centriole elongation", "d": ["Any process that activates or increases the frequency, rate or extent of centriole elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010661", "l": "positive regulation of muscle cell apoptotic process", "d": ["Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902972", "l": "premeiotic DNA replication DNA ligation", "d": ["Any DNA ligation involved in meiotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070560", "l": "protein secretion by platelet", "d": ["The regulated release of proteins by a platelet or group of platelets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1900543", "l": "negative regulation of purine nucleotide metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902072", "l": "negative regulation of hypoxia-inducible factor-1alpha signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021887", "l": "hypothalamus gonadotrophin-releasing hormone neuron fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a hypothalamus neuron that releases gonadotrophin-releasing hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905750", "l": "negative regulation of endosome to plasma membrane protein transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endosome to plasma membrane protein transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048498", "l": "establishment of petal orientation", "d": ["The process that determines the orientation of petals with reference to the central axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061451", "l": "retrotrapezoid nucleus development", "d": ["The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1901578", "l": "negative regulation of alkane biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of alkane biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061161", "l": "positive regulation of establishment of bipolar cell polarity regulating cell shape", "d": ["Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043289", "l": "apocarotenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of apocarotenoids by the oxidative cleavage of carotenoids. Many apocarotenoids are biologically important e.g. retinal and abscisic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048600", "l": "oocyte fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into an oocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0060632", "l": "regulation of microtubule-based movement", "d": ["Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014018", "l": "neuroblast fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a neuroblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046192", "l": "anaerobic phenol-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0098534", "l": "centriole assembly", "d": ["A cellular process that results in the assembly of one or more centrioles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033362", "l": "lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway", "d": ["The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in two enzymatic steps."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904643", "l": "response to curcumin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003150", "l": "muscular septum morphogenesis", "d": ["The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070803", "l": "negative regulation of metula development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070586", "l": "cell-cell adhesion involved in gastrulation", "d": ["The attachment of one cell to another cell affecting gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0097345", "l": "mitochondrial outer membrane permeabilization", "d": ["The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0098856", "l": "intestinal lipid absorption", "d": ["Any process in which lipids are taken up from the contents of the intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120268", "l": "paraflagellar rod assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a paraflagellar rod, a large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046667", "l": "compound eye retinal cell programmed cell death", "d": ["Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903856", "l": "regulation of cytokinin dehydrogenase activity", "d": ["Any process that modulates the frequency, rate or extent of cytokinin dehydrogenase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048491", "l": "retrograde synaptic vesicle transport", "d": ["The directed movement of synaptic vesicle along axonal microtubules from the presynapse to the cell body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035180", "l": "larval wandering behavior", "d": ["The movement of a third instar larva through a substrate in search of a pupation site. This movement occurs without feeding and is characterized by short bursts of forward movement, separated by stops and repeated side-to-side head probes, followed normally by a change in direction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0007567", "l": "parturition", "d": ["The reproductive process in which the parent is separated from its offspring either by giving birth to live young or by laying eggs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.415093686714229", "identifiers": [{"i": "GO:0010453", "l": "regulation of cell fate commitment", "d": ["Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045541", "l": "negative regulation of cholesterol biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045794", "l": "negative regulation of cell volume", "d": ["Any process that decreases cell volume."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042669", "l": "regulation of inner ear auditory receptor cell fate specification", "d": ["Any process that mediates the specification of a cell into an auditory hair cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072426", "l": "response to G2 DNA damage checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of G2/M transition DNA damage checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070707", "l": "RNA dinucleotide insertion", "d": ["The modification of an RNA molecule by insertion of a dinucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0034349", "l": "glial cell apoptotic process", "d": ["Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010742", "l": "macrophage derived foam cell differentiation", "d": ["The process in which a monocyte acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150073", "l": "regulation of protein-glutamine gamma-glutamyltransferase activity", "d": ["Any process that modulates the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110114", "l": "negative regulation of lipid transporter activity", "d": ["Any process that decreases the frequency, rate, or extent of lipid transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000805", "l": "negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072016", "l": "glomerular parietal epithelial cell development", "d": ["The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.362525179576039", "identifiers": [{"i": "GO:0006487", "l": "protein N-linked glycosylation", "d": ["A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000528", "l": "negative regulation of myeloid dendritic cell chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902153", "l": "regulation of response to DNA damage checkpoint signaling", "d": ["Any process that modulates the frequency, rate or extent of response to DNA damage checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:1901976", "l": "regulation of cell cycle checkpoint", "d": ["Any process that modulates the frequency, rate or extent of cell cycle checkpoint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002432", "l": "granuloma formation", "d": ["The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070947", "l": "neutrophil-mediated killing of fungus", "d": ["The directed killing of a fungal cell by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048026", "l": "positive regulation of mRNA splicing, via spliceosome", "d": ["Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160030", "l": "pollen intine formation", "d": ["Formation of pollen intine, the inner layer of the pollen wall. The reticulate pollen wall pattern consists of two layers, exine and intine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071871", "l": "response to epinephrine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903534", "l": "regulation of lactose biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of lactose biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002268", "l": "follicular dendritic cell differentiation", "d": ["The process in which a relatively unspecialized precursor cell acquires the specialized features of a follicular dendritic cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044503", "l": "modulation of G protein-coupled receptor activity in another organism", "d": ["The process in which an organism effects a change in the activity of a G protein-coupled receptor in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045633", "l": "positive regulation of mechanoreceptor differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006392", "l": "transcription elongation by mitochondrial RNA polymerase", "d": ["The extension of an RNA molecule after transcription initiation and promoter clearance at mitochondrial promoter by the addition of ribonucleotides catalyzed by a mitchondrial RNA polymerase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140433", "l": "regulation of protein localization to meiotic spindle pole body", "d": ["Any process that modulates the frequency, rate or extent of protein localization to a meiotic spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007137", "l": "meiotic metaphase II", "d": ["The cell cycle phase, following prophase II, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000458", "l": "regulation of astrocyte chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of astrocyte chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016330", "l": "second mitotic wave involved in compound eye morphogenesis", "d": ["A discrete cell cycle in the third instar eye imaginal disc after progression of the morphogenetic furrow that contributes to compound eye morphogenesis. It is essential for generation of a sufficient pool of uncommitted cells to develop complete ommatidia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034171", "l": "regulation of toll-like receptor 11 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 11 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990933", "l": "microtubule cytoskeleton attachment to nuclear envelope", "d": ["A process in which the microtubule cytoskeleton is attached to the nuclear envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0019577", "l": "aldaric acid metabolic process", "d": ["The chemical reactions and pathways involving aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.088418960336696", "identifiers": [{"i": "GO:0000226", "l": "microtubule cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010587", "l": "miRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0000209", "l": "protein polyubiquitination", "d": ["Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0032108", "l": "negative regulation of response to nutrient levels", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016345", "l": "female meiotic chromosome movement towards spindle pole", "d": ["The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during female meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002876", "l": "positive regulation of chronic inflammatory response to antigenic stimulus", "d": ["Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015716", "l": "organic phosphonate transport", "d": ["The directed movement of phosphonates into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051711", "l": "negative regulation of killing of cells of another organism", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the killing by an organism of cells in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:1901419", "l": "regulation of response to alcohol", "d": ["Any process that modulates the frequency, rate or extent of response to alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0036006", "l": "cellular response to macrophage colony-stimulating factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003355", "l": "cilium movement involved in otolith formation", "d": ["The directed, self-propelled movement of cilia of inner ear epithelial cells, resulting the aggregation of otolith seed particles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060723", "l": "regulation of cell proliferation involved in embryonic placenta development", "d": ["Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900487", "l": "regulation of [2Fe-2S] cluster assembly", "d": ["Any process that modulates the frequency, rate or extent of [2Fe-2S] cluster assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031425", "l": "chloroplast RNA processing", "d": ["The conversion of a primary RNA molecule transcribed from a chloroplast genome into one or more mature RNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060186", "l": "outer ear emergence", "d": ["The growth of the outer ear."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019273", "l": "L-alanine biosynthetic process via ornithine", "d": ["The chemical reactions and pathways resulting in the formation of L-alanine, via the intermediate ornithine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021707", "l": "cerebellar granule cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0048087", "l": "positive regulation of developmental pigmentation", "d": ["Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0062028", "l": "regulation of stress granule assembly", "d": ["Any process that modulates the rate, frequency or extent of stress granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006932", "l": "substrate-dependent cell migration, cell contraction", "d": ["The translocation of the cell body forward during cell migration, mediated by tractional force on its substrate and tension in the cortical cytoskeleton. Adhesions transmit propulsive forces and serve as traction points over which the cell moves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021749", "l": "ventral cochlear nucleus development", "d": ["The process whose specific outcome is the progression of the ventral cochlear nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002393", "l": "lysosomal enzyme production involved in inflammatory response", "d": ["The synthesis or release of lysosomal enzymes following a stimulus as part of a inflammatory response, resulting in an increase in intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019498", "l": "n-octane oxidation", "d": ["The chemical reactions and pathways resulting in the conversion of n-octane to octanoyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903255", "l": "hercynylselenocysteine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hercynylselenocysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021788", "l": "chemoattraction of branchiomotor neuron axon in neural tube", "d": ["The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905678", "l": "negative regulation of adaptive immune effector response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune effector response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051866", "l": "general adaptation syndrome", "d": ["General adaptation syndrome is the set of changes in various organ systems of the body, especially the pituitary-endocrine system, in response to a wide range of strong external stimuli, both physiological and psychological. It is described as having three stages: alarm reaction, where the body detects the external stimulus; adaptation, where the body engages defensive countermeasures against the stressor; and exhaustion, where the body begins to run out of defenses."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070662", "l": "mast cell proliferation", "d": ["The expansion of a mast cell population by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009810", "l": "stilbene metabolic process", "d": ["The chemical reactions and pathways involving stilbenes, a class of polyketides formed from a molecule of cinnamic acid and three molecules of malonyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044565", "l": "dendritic cell proliferation", "d": ["The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.062476272212777", "identifiers": [{"i": "GO:0051603", "l": "proteolysis involved in protein catabolic process", "d": ["The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.636998499829652", "identifiers": [{"i": "GO:0045165", "l": "cell fate commitment", "d": ["The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048302", "l": "regulation of isotype switching to IgG isotypes", "d": ["Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021520", "l": "spinal cord motor neuron cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.965407664364811", "identifiers": [{"i": "GO:0009892", "l": "negative regulation of metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0051224", "l": "negative regulation of protein transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990689", "l": "endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with Golgi cis cisterna membrane", "d": ["The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPII-coated transport vesicles involved in anterograde transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0070942", "l": "neutrophil mediated cytotoxicity", "d": ["The directed killing of a target cell by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034232", "l": "ascospore wall chitin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0043647", "l": "inositol phosphate metabolic process", "d": ["The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140958", "l": "target-directed miRNA degradation", "d": ["The process in which a miRNA is targeted for degradation by a non-coding RNA or mRNA. The binding of an RNA to a target miRNA within a RISC complex results in either ubiquitin-mediated degradation of AGO protein or the displacement of the 3' end of the miRNA, exposing it to nucleases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0014869", "l": "detection of muscle inactivity", "d": ["The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903657", "l": "negative regulation of type IV pilus biogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of type IV pilus biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141007", "l": "siRNA-mediated retrotransposon silencing by heterochromatin formation", "d": ["A retrotransposon silencing mechanism in which a siRNA triggers heterochromatin assembly. Heterochromatin is a chromatin conformation that is refractory to transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140633", "l": "CARD8 inflammasome complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a CARD8 inflammasome complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0052801", "l": "bicyclic nitroimidazole metabolic process", "d": ["The chemical reactions and pathways involving bicyclic nitroimidazoles, imidazole derivatives with two rings and a nitro group attached to one ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051083", "l": "'de novo' cotranslational protein folding", "d": ["The process of assisting in the correct noncovalent assembly of the ribosome-bound nascent chains of a multidomain protein whilst other parts of the protein are still being translated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140781", "l": "ilicicolin H biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ilicicolin H, a 4-hydroxy-2-pyridone alkaloid that has potent and broad antifungal activities by inhibiting the mitochondrial respiration chain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0042373", "l": "vitamin K metabolic process", "d": ["The chemical reactions and pathways involving any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0031923", "l": "pyridoxine transport", "d": ["The directed movement of pyridoxine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061621", "l": "canonical glycolysis", "d": ["The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900763", "l": "averantin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of averantin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900075", "l": "positive regulation of neuromuscular synaptic transmission", "d": ["Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0060113", "l": "inner ear receptor cell differentiation", "d": ["The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046213", "l": "methyl ethyl ketone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905916", "l": "negative regulation of cell differentiation involved in phenotypic switching", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation involved in phenotypic switching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903948", "l": "negative regulation of atrial cardiac muscle cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of atrial cardiac muscle cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902063", "l": "betaine aldehyde biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of betaine aldehyde."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905303", "l": "positive regulation of macropinocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of macropinocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0007431", "l": "salivary gland development", "d": ["The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048772", "l": "leucophore differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a leucophore cell. Leucophores are pigment cells derived from the neural crest. They contain uric acid or other purine crystals, deposited in stacks called leucosomes. This gives them a white appearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.725591100956891", "identifiers": [{"i": "GO:0044706", "l": "multi-multicellular organism process", "d": ["A multicellular organism process which involves another multicellular organism of the same or different species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106147", "l": "fraxetin biosynthesis", "d": ["The chemical reactions and pathways resulting in the formation of fraxetin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097279", "l": "histamine secretion mediated by IgE immunoglobulin", "d": ["Histamine release triggered by the binding of an antigen to an IgE immunoglobulin bound to the cell surface. An example is mast cell histamine degranulation as a result of exposure of mast cell-bound IgE to alder tree pollen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0043045", "l": "post-fertilization epigenetic regulation of gene expression", "d": ["A epigenetic process that happens during embryonic development that modulates gene expression potential at later stages of development of the organism, including the adult. Epigenetic regulation takes place via chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine DNA methylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097150", "l": "neuronal stem cell population maintenance", "d": ["Any process in by an organism or tissue maintains a population of neuronal stem cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904453", "l": "positive regulation of potassium:proton exchanging ATPase activity", "d": ["Any process that activates or increases the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905826", "l": "negative regulation of selenocysteine metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900579", "l": "(17Z)-protosta-17(20),24-dien-3beta-ol metabolic process", "d": ["The chemical reactions and pathways involving (17Z)-protosta-17(20),24-dien-3beta-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1904580", "l": "regulation of intracellular mRNA localization", "d": ["Any process that modulates the frequency, rate or extent of intracellular mRNA localization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0042451", "l": "purine nucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0001991", "l": "regulation of systemic arterial blood pressure by circulatory renin-angiotensin", "d": ["The process in which angiotensinogen metabolites in the bloodstream modulate the force with which blood passes through the circulatory system. The process begins when renin is released and cleaves angiotensinogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901495", "l": "negative regulation of cysteine metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cysteine metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0050926", "l": "regulation of positive chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1901723", "l": "negative regulation of cell proliferation involved in kidney development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072024", "l": "macula densa development", "d": ["The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021793", "l": "chemorepulsion of branchiomotor axon", "d": ["The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001176", "l": "regulation of mediator complex assembly", "d": ["Any process that modulates the frequency, rate or extent of mediator complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0030473", "l": "nuclear migration along microtubule", "d": ["The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046156", "l": "siroheme metabolic process", "d": ["The chemical reactions and pathways involving siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045651", "l": "positive regulation of macrophage differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903927", "l": "response to cyanide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019470", "l": "4-hydroxyproline catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046248", "l": "alpha-pinene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060996", "l": "dendritic spine development", "d": ["The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0048242", "l": "epinephrine secretion", "d": ["The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003226", "l": "right ventricular compact myocardium morphogenesis", "d": ["The process in which the anatomical structures of the right ventricular compact myocardium are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001223", "l": "negative regulation of neuron migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0055012", "l": "ventricular cardiac muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090241", "l": "negative regulation of histone H4 acetylation", "d": ["Any process that decreases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061309", "l": "cardiac neural crest cell development involved in outflow tract morphogenesis", "d": ["The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0110073", "l": "regulation of apical constriction involved in ventral furrow formation", "d": ["Any process that modulates the frequency, rate or extent of apical constriction involved in ventral furrow formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032306", "l": "regulation of prostaglandin secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of a prostaglandin from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035127", "l": "post-embryonic limb morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0009855", "l": "determination of bilateral symmetry", "d": ["The establishment of an organism's body plan or part of an organism with respect to a single longitudinal plane. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0009226", "l": "nucleotide-sugar biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106426", "l": "regulation of kainate selective glutamate receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of tge kainate selective glutamate receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.939870552020253", "identifiers": [{"i": "GO:0009952", "l": "anterior/posterior pattern specification", "d": ["The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010575", "l": "positive regulation of vascular endothelial growth factor production", "d": ["Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061818", "l": "tRNA folding", "d": ["The process of assisting in the folding of tRNAs into the correct tertiary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0010114", "l": "response to red light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140043", "l": "lipid droplet localization to prospore membrane leading edge", "d": ["Any process in which a lipid droplet is transported to, or maintained to the prospore membrane leading edge."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071653", "l": "negative regulation of chemokine (C-C motif) ligand 1 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:2000273", "l": "positive regulation of signaling receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of signaling receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009094", "l": "L-phenylalanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002597", "l": "positive regulation of antigen processing and presentation of peptide antigen via MHC class Ib", "d": ["Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010890", "l": "positive regulation of sequestering of triglyceride", "d": ["Any process that increases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071873", "l": "response to norepinephrine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097739", "l": "negative regulation of ferrichrome biosynthetic process in response to iron", "d": ["Any process that stops, prevents or reduces the rate of ferrichrome biosynthetic process in response to an iron stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043407", "l": "negative regulation of MAP kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0007309", "l": "oocyte axis specification", "d": ["The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046107", "l": "uracil biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901645", "l": "regulation of synoviocyte proliferation", "d": ["Any process that modulates the frequency, rate or extent of synoviocyte proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098934", "l": "retrograde dendritic transport", "d": ["The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905043", "l": "positive regulation of epithelium regeneration", "d": ["Any process that activates or increases the frequency, rate or extent of epithelium regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033307", "l": "phytol salvage", "d": ["A process that generates phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol, from derivatives of it without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003163", "l": "sinoatrial node development", "d": ["The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0099515", "l": "actin filament-based transport", "d": ["The transport of organelles or other particles from one location in the cell to another along actin filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.381173084437549", "identifiers": [{"i": "GO:0042445", "l": "hormone metabolic process", "d": ["The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001256", "l": "regulation of store-operated calcium entry", "d": ["Any process that modulates the frequency, rate or extent of store-operated calcium entry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0106091", "l": "glial cell projection elongation", "d": ["The process of creating an elongation or projection from a glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032752", "l": "positive regulation of interleukin-3 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-3 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003273", "l": "cell migration involved in endocardial cushion formation", "d": ["The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060958", "l": "endocardial cell development", "d": ["The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033539", "l": "fatty acid beta-oxidation using acyl-CoA dehydrogenase", "d": ["A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA dehydrogenase; the electrons removed by oxidation pass through the respiratory chain to oxygen and leave H2O as the product. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052704", "l": "ergothioneine biosynthesis from histidine via gamma-glutamyl-hercynylcysteine sulfoxide", "d": ["The pathway resulting in the formation of ergothioneine from histidine via a set of steps in which gamma-glutamyl-hercynylcysteine sulfoxide is formed as an intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051663", "l": "oocyte nucleus localization involved in oocyte dorsal/ventral axis specification", "d": ["The directed movement of the nucleus to a specific location within a cell during the establishment and maintenance of the dorsal/ventral axis of the oocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903279", "l": "regulation of calcium:sodium antiporter activity", "d": ["Any process that modulates the frequency, rate or extent of calcium:sodium antiporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1902307", "l": "positive regulation of sodium ion transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010057", "l": "trichoblast fate specification", "d": ["The process involved in the specification of a trichoblast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070682", "l": "proteasome regulatory particle assembly", "d": ["The aggregation, arrangement and bonding together of a mature, active proteasome regulatory particle complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901170", "l": "naphthalene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of naphthalene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039513", "l": "suppression by virus of host catalytic activity", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host enzyme activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031921", "l": "pyridoxal phosphate transport", "d": ["The directed movement of pyridoxal phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904886", "l": "beta-catenin destruction complex disassembly", "d": ["The disaggregation of a beta-catenin destruction complex into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046499", "l": "S-adenosylmethioninamine metabolic process", "d": ["The chemical reactions and pathways involving S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032724", "l": "positive regulation of fractalkine production", "d": ["Any process that activates or increases the frequency, rate, or extent of fractalkine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070806", "l": "negative regulation of phialide development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035878", "l": "nail development", "d": ["The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904793", "l": "regulation of euchromatin binding", "d": ["Any process that modulates the frequency, rate or extent of euchromatin binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051547", "l": "regulation of keratinocyte migration", "d": ["Any process that modulates the frequency, rate or extent of keratinocyte migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.646478505545467", "identifiers": [{"i": "GO:0051656", "l": "establishment of organelle localization", "d": ["The directed movement of an organelle to a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075246", "l": "negative regulation of oospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140041", "l": "cellular detoxification of methylglyoxal", "d": ["Any process carried out at the cellular level that reduces or removes the toxicity of methylglyoxal. These may include chemical modification or transport of methylglyoxal away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002933", "l": "lipid hydroxylation", "d": ["The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008058", "l": "ocellus pigment granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the ocellus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019568", "l": "arabinose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of arabinose, arabino-pentose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006535", "l": "cysteine biosynthetic process from serine", "d": ["The chemical reactions and pathways resulting in the formation of cysteine from other compounds, including serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0031644", "l": "regulation of nervous system process", "d": ["Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0021772", "l": "olfactory bulb development", "d": ["The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990217", "l": "suppression by symbiont of host phytoalexin production", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of phytoalexin production in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902839", "l": "negative regulation of nuclear migration along microtubule", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000754", "l": "regulation of sphingomyelin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of sphingomyelin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045743", "l": "positive regulation of fibroblast growth factor receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:2000889", "l": "cellodextrin metabolic process", "d": ["The chemical reactions and pathways involving a cellodextrin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046446", "l": "purine alkaloid metabolic process", "d": ["The chemical reactions and pathways involving purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990556", "l": "mitochondrial isopropylmalate transmembrane transport", "d": ["The process in which 2-isopropylmalate(2-) is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099632", "l": "protein transport within plasma membrane", "d": ["A process in which protein is transported from one region of the plasma membrane to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032077", "l": "positive regulation of deoxyribonuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900158", "l": "negative regulation of bone mineralization involved in bone maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bone mineralization involved in bone maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904723", "l": "negative regulation of Wnt-Frizzled-LRP5/6 complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002439", "l": "chronic inflammatory response to antigenic stimulus", "d": ["A chronic inflammatory response to an antigenic stimulus. A chronic inflammatory response persists indefinitely during days, weeks, or months in the life of an individual."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060064", "l": "Spemann organizer formation at the anterior end of the primitive streak", "d": ["Formation of the specialized region at the anterior end of the primitive streak of the embryo that acts as the main signaling center establishing the body plan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905335", "l": "regulation of aggrephagy", "d": ["Any process that modulates the frequency, rate or extent of aggrephagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019647", "l": "formaldehyde assimilation via ribulose monophosphate cycle", "d": ["The pathway in which formaldehyde is used as a carbon source in the ribulose monophosphate cycle. Methanotrophic bacteria produce formaldehyde from the oxidation of methane and methanol, and then assimilate it via the ribulose monophosphate cycle to form intermediates of the central metabolic routes that are subsequently used for biosynthesis of cell material. Three molecules of formaldehyde are assimilated, forming a three-carbon intermediate of central metabolism; in this pathway, all cellular carbon is assimilated at the oxidation level of formaldehyde."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042338", "l": "cuticle development involved in collagen and cuticulin-based cuticle molting cycle", "d": ["Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this process is found in Caenorhabditis elegans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0061224", "l": "mesonephric glomerulus development", "d": ["The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904585", "l": "response to putrescine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904457", "l": "positive regulation of neuronal action potential", "d": ["Any process that activates or increases the frequency, rate or extent of neuronal action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032014", "l": "positive regulation of ARF protein signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of ARF protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032676", "l": "regulation of interleukin-7 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-7 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046179", "l": "keto-D-gluconate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007074", "l": "positive regulation of transcription involved in exit from mitosis, from RNA polymerase II promoter", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033138", "l": "positive regulation of peptidyl-serine phosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990922", "l": "hepatic stellate cell proliferation", "d": ["The multiplication or reproduction of hepatic stellate cells, resulting in the expansion of a hepatic stellate cell population. Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0044071", "l": "modulation by symbiont of host cell cycle", "d": ["The process in which a symbiont organism effects a change in its host's cell cycle through direct interactions with the host cell macromolecular machinery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904913", "l": "regulation of establishment of protein-containing complex localization to telomere", "d": ["Any process that modulates the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0008089", "l": "anterograde axonal transport", "d": ["The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903950", "l": "negative regulation of AV node cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045494", "l": "photoreceptor cell maintenance", "d": ["Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046171", "l": "octanol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of octanol, the 8-carbon alcohol with the formula C8H17OH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901400", "l": "positive regulation of transforming growth factor beta3 activation", "d": ["Any process that activates or increases the frequency, rate or extent of transforming growth factor beta3 activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.689198976159247", "identifiers": [{"i": "GO:0050882", "l": "voluntary musculoskeletal movement", "d": ["The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system that can be controlled at will."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046306", "l": "alkanesulfonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0000742", "l": "karyogamy involved in conjugation with cellular fusion", "d": ["During sexual reproduction, the creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. This occurs after cytogamy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901534", "l": "positive regulation of hematopoietic progenitor cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019281", "l": "L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine", "d": ["The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-succinyl-L-homoserine and cystathionine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044348", "l": "plant-type cell wall cellulose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, which forms part of the cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160034", "l": "positive regulation of Toll receptor ligand protein activation cascade", "d": ["Any process that activates or increases the frequency, rate or extent of Toll receptor ligand protein activation cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007158", "l": "neuron cell-cell adhesion", "d": ["The attachment of a neuron to another cell via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003110", "l": "positive regulation of the force of heart contraction by neuronal norepinephrine", "d": ["The process in which the release of norepinephrine from nerve endings modulates the force of heart muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034176", "l": "negative regulation of toll-like receptor 12 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 12 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043306", "l": "positive regulation of mast cell degranulation", "d": ["Any process that activates or increases the frequency, rate or extent of mast cell degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904848", "l": "negative regulation of cell chemotaxis to fibroblast growth factor", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell chemotaxis to fibroblast growth factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000494", "l": "positive regulation of interleukin-18-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-18-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0034092", "l": "negative regulation of maintenance of sister chromatid cohesion", "d": ["Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0032885", "l": "regulation of polysaccharide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904038", "l": "regulation of iron export across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042358", "l": "thiamine diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901807", "l": "capsanthin metabolic process", "d": ["The chemical reactions and pathways involving capsanthin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901964", "l": "positive regulation of cell proliferation involved in outflow tract morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021650", "l": "vestibulocochlear nerve formation", "d": ["The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075247", "l": "aeciospore formation", "d": ["The process in which a dikaryotic spore of typically a rust fungus is produced in an aecium; in heteroecious rusts, the aeciospore is a spore stage that infects the alternate host."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033623", "l": "regulation of integrin activation", "d": ["Any process that modulates the frequency, rate, or extent of integrin activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.959712637402532", "identifiers": [{"i": "GO:0032870", "l": "cellular response to hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106236", "l": "rhamnolipid biosynthesis", "d": ["The chemical reactions and pathways resulting in the formation/production of a glycolipid surfactant that acts as a bacterial biofilm dispersal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009234", "l": "menaquinone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0060029", "l": "convergent extension involved in organogenesis", "d": ["The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contribution to the shaping of an organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097353", "l": "centrolateral pattern formation", "d": ["The regionalization process in which the areas along the centrolateral axis are established that will lead to differences in cell differentiation, or in which cells interpret a specific environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000204", "l": "negative regulation of ribosomal large subunit export from nucleus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal large subunit export from nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.473338630929121", "identifiers": [{"i": "GO:0072009", "l": "nephron epithelium development", "d": ["The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009559", "l": "embryo sac central cell differentiation", "d": ["The process in which the two uncellularized polar nuclei cellularize, fuse and acquire the specialized features of a mononucleate diploid central cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0021543", "l": "pallium development", "d": ["The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.550707717106313", "identifiers": [{"i": "GO:0009913", "l": "epidermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071497", "l": "cellular response to freezing", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061674", "l": "gap filling involved in double-strand break repair via nonhomologous end joining", "d": ["Repair of the gaps in the DNA helix using a discontinuous template during double-strand break repair via nonhomologous end joining."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060023", "l": "soft palate development", "d": ["The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.934711109505606", "identifiers": [{"i": "GO:0014047", "l": "glutamate secretion", "d": ["The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:1903038", "l": "negative regulation of leukocyte cell-cell adhesion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0060415", "l": "muscle tissue morphogenesis", "d": ["The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0038016", "l": "insulin receptor internalization", "d": ["A receptor-mediated endocytosis process that results in the movement of an insulin receptor from the plasma membrane to the inside of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0044826", "l": "viral genome integration into host DNA", "d": ["The insertion into a host genome of viral DNA, usually by the action of an integrase enzyme. Once integrated, the provirus persists in the host cell and serves as a template for the transcription of viral genes and replication of the viral genome, leading to the production of new viruses."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0048859", "l": "formation of anatomical boundary", "d": ["The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901961", "l": "isobutanol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isobutanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "28.332585464545698", "identifiers": [{"i": "GO:0048856", "l": "anatomical structure development", "d": ["The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046071", "l": "dGTP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dGTP, guanosine triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0030917", "l": "midbrain-hindbrain boundary development", "d": ["The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000591", "l": "positive regulation of metanephric mesenchymal cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of metanephric mesenchymal cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0099548", "l": "trans-synaptic signaling by nitric oxide", "d": ["Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032816", "l": "positive regulation of natural killer cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000176", "l": "positive regulation of pro-T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900066", "l": "positive regulation of ethanol catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of ethanol catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903006", "l": "positive regulation of protein K63-linked deubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein K63-linked deubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010424", "l": "DNA methylation on cytosine within a CG sequence", "d": ["The covalent transfer of a methyl group to C-5 or N-4 of a cytosine located within a CG sequence in a DNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000437", "l": "regulation of monocyte extravasation", "d": ["Any process that modulates the frequency, rate or extent of monocyte extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071139", "l": "resolution of recombination intermediates", "d": ["The cleavage and rejoining of intermediates, such as Holliday junctions, formed during DNA recombination to produce two intact molecules in which genetic material has been exchanged."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051256", "l": "mitotic spindle midzone assembly", "d": ["The cell cycle process in which the aggregation, arrangement and bonding together of a set of components forms the spindle midzone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060623", "l": "regulation of chromosome condensation", "d": ["Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905448", "l": "positive regulation of mitochondrial ATP synthesis coupled electron transport", "d": ["Any process that activates or increases the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0034368", "l": "protein-lipid complex remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within a protein-lipid complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051486", "l": "isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate pathway that contributes to terpenoid biosynthesis. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007402", "l": "ganglion mother cell fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into a ganglion mother cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0007525", "l": "somatic muscle development", "d": ["The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017180", "l": "peptidyl-diphthine biosynthetic process from peptidyl-histidine", "d": ["The chemical reactions and pathways resulting in the formation of peptidyl-diphthine from other compounds, including peptidyl-histidine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031142", "l": "induction of conjugation upon nitrogen starvation", "d": ["The process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008071", "l": "maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded", "d": ["Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by somatic cells. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075315", "l": "positive regulation of basidium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046622", "l": "positive regulation of organ growth", "d": ["Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905665", "l": "positive regulation of calcium ion import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097294", "l": "'de novo' XMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate, from simpler precursors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009773", "l": "photosynthetic electron transport in photosystem I", "d": ["A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, X) through a chain of electron transport molecules in the thylakoid membrane until they reach ferredoxin which passes the electron to the ultimate electron acceptor; NADP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048325", "l": "negative regulation of axial mesodermal cell fate determination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0035196", "l": "miRNA processing", "d": ["A process leading to the generation of a functional miRNA. Includes the cleavage of stem-loop RNA precursors into microRNAs (miRNAs). miRNAs are a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein, or by increasing the degradation of non-protein-coding RNA transcripts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900243", "l": "negative regulation of synaptic vesicle endocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032229", "l": "negative regulation of synaptic transmission, GABAergic", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048149", "l": "behavioral response to ethanol", "d": ["Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903999", "l": "negative regulation of eating behavior", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904005", "l": "regulation of phospholipase D activity", "d": ["Any process that modulates the frequency, rate or extent of phospholipase D activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0110095", "l": "cellular detoxification of aldehyde", "d": ["Any process carried out at the cellular level that reduces or removes the toxicity of an aldehyde. These may include transport of aldehydes away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.000891501185137", "identifiers": [{"i": "GO:0045137", "l": "development of primary sexual characteristics", "d": ["The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901995", "l": "positive regulation of meiotic cell cycle phase transition", "d": ["Any process that activates or increases the frequency, rate or extent of meiotic cell cycle phase transition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061855", "l": "negative regulation of neuroblast migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0007519", "l": "skeletal muscle tissue development", "d": ["The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021725", "l": "superior raphe nucleus development", "d": ["The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071410", "l": "cellular response to cyclopentenone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0050427", "l": "3'-phosphoadenosine 5'-phosphosulfate metabolic process", "d": ["The chemical reactions and pathways involving 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046217", "l": "indole phytoalexin metabolic process", "d": ["The chemical reactions and pathways involving indole phytoalexins, any indole compound produced by plants as part of their defense response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900629", "l": "methanophenazine metabolic process", "d": ["The chemical reactions and pathways involving methanophenazine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098514", "l": "detection of high humidity stimulus involved in sensory perception", "d": ["The series of events in which a high humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of high humidity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0099010", "l": "modification of postsynaptic structure", "d": ["Any process that modifies the structure of a postsynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035645", "l": "enteric smooth muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0039694", "l": "viral RNA genome replication", "d": ["The replication of a viral RNA genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046641", "l": "positive regulation of alpha-beta T cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of alpha-beta T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090291", "l": "negative regulation of osteoclast proliferation", "d": ["Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071278", "l": "cellular response to cesium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903445", "l": "protein transport from ciliary membrane to plasma membrane", "d": ["The directed movement of protein from ciliary membrane to plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021561", "l": "facial nerve development", "d": ["The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033336", "l": "caudal fin development", "d": ["The process whose specific outcome is the progression of the caudal fin over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900573", "l": "emodin metabolic process", "d": ["The chemical reactions and pathways involving emodin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0071027", "l": "nuclear RNA surveillance", "d": ["A process that identifies and degrades defective or aberrant RNAs within the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010501", "l": "RNA secondary structure unwinding", "d": ["The process in which a secondary structure of RNA are broken or 'melted'."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002813", "l": "regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria", "d": ["Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071611", "l": "granulocyte colony-stimulating factor production", "d": ["The appearance of granulocyte colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009298", "l": "GDP-mannose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901767", "l": "carbapenem metabolic process", "d": ["The chemical reactions and pathways involving carbapenem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031494", "l": "regulation of mating type switching", "d": ["Any process that modulates the frequency, rate or extent of mating type switching, the conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904374", "l": "cellular response to kainic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010808", "l": "positive regulation of synaptic vesicle priming", "d": ["Any process that increases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902357", "l": "2-isopropylmalate(2-) transmembrane transport", "d": ["The process in which 2-isopropylmalate(2-) is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033474", "l": "indoleacetic acid conjugate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002745", "l": "antigen processing and presentation initiated by receptor mediated uptake of antigen", "d": ["Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0060441", "l": "epithelial tube branching involved in lung morphogenesis", "d": ["The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060635", "l": "positive regulation of (1->3)-beta-D-glucan biosynthetic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018959", "l": "aerobic phenol-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.843307841253292", "identifiers": [{"i": "GO:0050962", "l": "detection of light stimulus involved in sensory perception", "d": ["The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0019321", "l": "pentose metabolic process", "d": ["The chemical reactions and pathways involving a pentose, any monosaccharide with a chain of five carbon atoms in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0030858", "l": "positive regulation of epithelial cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901855", "l": "5,6,7,8-tetrahydrosarcinapterin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydrosarcinapterin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0016539", "l": "intein-mediated protein splicing", "d": ["The removal of an internal amino acid sequence (an intein) from a protein during protein maturation; the excision of inteins is precise and the N- and C-terminal exteins are joined by a normal peptide bond. Protein splicing involves 4 nucleophilic displacements by the 3 conserved splice junction residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0030728", "l": "ovulation", "d": ["The release of a mature ovum/oocyte from an ovary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904736", "l": "negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071594", "l": "thymocyte aggregation", "d": ["The adhesion of one thymocyte (an immature T cell) to one or more other thymocytes via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018880", "l": "4-chlorobiphenyl metabolic process", "d": ["The chemical reactions and pathways involving 4-chlorobiphenyl, a member of the polychlorinated biphenyl (PCB) group of compounds, a very stable group of synthetic organic compounds composed of a biphenyl nucleus with 1-10 chlorine substituents. 4-chlorobiphenyl has been used as a model substrate to investigate PCB degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048691", "l": "positive regulation of axon extension involved in regeneration", "d": ["Any process that activates, maintains or increases the rate of axon extension involved in regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.470950656012619", "identifiers": [{"i": "GO:0006833", "l": "water transport", "d": ["The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060521", "l": "mesenchymal-epithelial cell signaling involved in prostate induction", "d": ["Signaling at short range from urogenital sinus mesenchymal cells to cells of the urogenital epithelium resulting in the epithelial cells adopting a prostatic fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071463", "l": "cellular response to humidity", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "47.652916243075964", "identifiers": [{"i": "GO:0003013", "l": "circulatory system process", "d": ["A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009802", "l": "cinnamic acid ester biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ester derivatives of cinnamic acid, phenylpropenoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009441", "l": "glycolate metabolic process", "d": ["The chemical reactions and pathways involving glycolate, the anion of hydroxyethanoic acid (glycolic acid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006769", "l": "nicotinamide metabolic process", "d": ["The chemical reactions and pathways involving nicotinamide, pyridine-3-carboxamide, the amide of nicotinic acid. It is a member of the B complex of vitamins and occurs widely in living organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:1900377", "l": "negative regulation of secondary metabolite biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0007310", "l": "oocyte dorsal/ventral axis specification", "d": ["The establishment, maintenance and elaboration of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031024", "l": "interphase microtubule organizing center assembly", "d": ["The aggregation, arrangement and bonding together of a set of components, including gamma-tubulin and other proteins, to form an interphase microtubule organizing center."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000491", "l": "small nucleolar ribonucleoprotein complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins and a snoRNA to form a small nucleolar ribonucleoprotein (snoRNP) complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046085", "l": "adenosine metabolic process", "d": ["The chemical reactions and pathways involving adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021647", "l": "vestibulocochlear nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0006911", "l": "phagocytosis, engulfment", "d": ["The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.139845358389962", "identifiers": [{"i": "GO:0070661", "l": "leukocyte proliferation", "d": ["The expansion of a leukocyte population by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032632", "l": "interleukin-3 production", "d": ["The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905229", "l": "cellular response to thyrotropin-releasing hormone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900899", "l": "regulation of heptadecane metabolic process", "d": ["Any process that modulates the frequency, rate or extent of heptadecane metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019325", "l": "anaerobic fructose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903489", "l": "positive regulation of lactation", "d": ["Any process that activates or increases the frequency, rate or extent of lactation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0002367", "l": "cytokine production involved in immune response", "d": ["The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046336", "l": "ethanolamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010705", "l": "meiotic DNA double-strand break processing involved in reciprocal meiotic recombination", "d": ["The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs resulting in double strand break formation and repair through a double Holliday junction intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060646", "l": "internal mammary gland bud epithelial cell differentiation", "d": ["The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an internal epithelial cell of the mammary gland bud. Internal cells are small and of irregular shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036040", "l": "curcumin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the polyphenol, curcumin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2000144", "l": "positive regulation of DNA-templated transcription initiation", "d": ["Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1904458", "l": "regulation of substance P secretion", "d": ["Any process that modulates the frequency, rate or extent of substance P secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051014", "l": "actin filament severing", "d": ["The process in which an actin filament is broken down into smaller filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014703", "l": "oscillatory muscle contraction", "d": ["A process in which force is generated within oscillatory skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Oscillatory muscle contraction occurs in insect wing muscles and is characterized by asynchrony between action potential and contraction and by stretch activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006245", "l": "TDP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of TDP, ribosylthymine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060169", "l": "negative regulation of adenosine receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:2000282", "l": "regulation of cellular amino acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060413", "l": "atrial septum morphogenesis", "d": ["The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0002323", "l": "natural killer cell activation involved in immune response", "d": ["The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0015727", "l": "lactate transport", "d": ["The directed movement of lactate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070275", "l": "aerobic ammonia oxidation to nitrite via pyruvic oxime", "d": ["The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen. Hydroxylamine is produced enzymatically, and, in the presence of pyruvate, forms pyruvic oxime in a spontaneous, non-enzymatic reaction; pyruvic oxime is then converted to nitrite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048784", "l": "pigment biosynthetic process involved in pigment granule maturation", "d": ["The chemical reactions and pathways resulting in the formation of a pigment, contributing to the process in which a membrane-bounded organelle develops into a pigment granule. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0007032", "l": "endosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045656", "l": "negative regulation of monocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:1903115", "l": "regulation of actin filament-based movement", "d": ["Any process that modulates the frequency, rate or extent of actin filament-based movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048677", "l": "axon extension involved in regeneration", "d": ["Long distance growth of a single axon process involved in regeneration of the neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062230", "l": "negative regulation of larval somatic muscle development", "d": ["Any process that decreases the rate, frequency or extent of larval somatic muscle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901798", "l": "positive regulation of signal transduction by p53 class mediator", "d": ["Any process that activates or increases the frequency, rate or extent of signal transduction by p53 class mediator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010337", "l": "regulation of salicylic acid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving salicylic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060011", "l": "Sertoli cell proliferation", "d": ["The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070291", "l": "N-acylethanolamine metabolic process", "d": ["The chemical reactions and pathways involving N-acylethanolamines. An N-acylethanolamine is an ethanolamine substituted at nitrogen by an acyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035779", "l": "angioblast cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0044561", "l": "modulation of ion channel activity in another organism", "d": ["Any process in which an organism effects a change in the frequency, rate or extent of the activity of an ion channel in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0009834", "l": "plant-type secondary cell wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall after cell expansion is complete. An example of this is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046190", "l": "aerobic phenol-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0008204", "l": "ergosterol metabolic process", "d": ["The chemical reactions and pathways involving ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds. It is the most important of the D provitamins and is converted to vitamin D2 on irradiation with UV light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048932", "l": "myelination of posterior lateral line nerve axons", "d": ["The formation of compact myelin sheaths around the axons of the posterior lateral line nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007161", "l": "calcium-independent cell-matrix adhesion", "d": ["The binding of a cell to the extracellular matrix via adhesion molecules that do not require the presence of calcium for the interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0070507", "l": "regulation of microtubule cytoskeleton organization", "d": ["Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072673", "l": "lamellipodium morphogenesis", "d": ["A process that is carried out at the cellular level and in which the structure of a lamellipodium is organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000765", "l": "response to pheromone regulating pheromone-induced unidirectional conjugation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that regulates the process of pheromone-induced unidirectional conjugation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901832", "l": "all-trans-neoxanthin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of all-trans-neoxanthin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0018933", "l": "nicotine metabolic process", "d": ["The chemical reactions and pathways involving nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010935", "l": "regulation of macrophage cytokine production", "d": ["Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060018", "l": "astrocyte fate commitment", "d": ["The commitment of a cells to a specific astrocyte fate and its restriction to develop only into an astrocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018146", "l": "keratan sulfate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.871876592857262", "identifiers": [{"i": "GO:0032350", "l": "regulation of hormone metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0000957", "l": "mitochondrial RNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0016128", "l": "phytosteroid metabolic process", "d": ["The chemical reactions and pathways involving phytosteroids, steroids of higher plants that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009911", "l": "positive regulation of flower development", "d": ["Any process that activates or increases the frequency, rate or extent of flower development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0030157", "l": "pancreatic juice secretion", "d": ["The regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904224", "l": "negative regulation of glucuronosyltransferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucuronosyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140040", "l": "mitochondrial polycistronic RNA processing", "d": ["The conversion of polycistronic RNA transcribed from a mitochondrial genome into mono- or bi-cistronic RNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0038017", "l": "Wnt receptor internalization", "d": ["A receptor-mediated endocytosis process that results in the movement of a Wnt receptor from the plasma membrane to the inside of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0015780", "l": "nucleotide-sugar transmembrane transport", "d": ["The directed movement of nucleotide-sugars into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nucleotide-sugars are any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002846", "l": "regulation of T cell tolerance induction to tumor cell", "d": ["Any process that modulates the frequency, rate, or extent of T cell tolerance induction to tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034445", "l": "negative regulation of plasma lipoprotein oxidation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein particle oxidation, occurring in the blood plasma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0035916", "l": "modulation of calcium channel activity in another organism", "d": ["Any process in which an organism effects a change in the frequency, rate or extent of the activity of a calcium channel in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0008358", "l": "maternal determination of anterior/posterior axis, embryo", "d": ["The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072733", "l": "response to staurosporine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900949", "l": "positive regulation of isoprene biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of isoprene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0071515", "l": "mating-type locus imprinting", "d": ["A genomic imprinting process in which a stable single-strand DNA lesion triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905715", "l": "regulation of cornification", "d": ["Any process that modulates the frequency, rate or extent of cornification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0009668", "l": "plastid membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of either of the lipid bilayers surrounding a plastid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019266", "l": "asparagine biosynthetic process from oxaloacetate", "d": ["The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including oxaloacetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0001574", "l": "ganglioside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140977", "l": "cellular detoxification of acetone", "d": ["Any process carried out at the cellular level that reduces or removes the toxicity of acetone. These may include chemical modification, for example to methylglyoxal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070286", "l": "axonemal dynein complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097350", "l": "neutrophil clearance", "d": ["The selective elimination of senescent neutrophils from the body by autoregulatory mechanisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090143", "l": "nucleoid organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleoid. The nucleoid is the region of a bacterial cell, virion, mitochondrion or chloroplast to which the DNA is confined."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0046129", "l": "purine ribonucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900318", "l": "regulation of methane biosynthetic process from dimethylamine", "d": ["Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900005", "l": "positive regulation of serine-type endopeptidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of serine-type endopeptidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900714", "l": "negative regulation of violaceol I biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of violaceol I biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048401", "l": "negative regulation of intermediate mesodermal cell fate specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052003", "l": "disruption of defense-related host salicylic acid-mediated signal transduction pathway", "d": ["Any process in which a symbiont interferes with host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120257", "l": "peptidyl-threonine acetylation", "d": ["The acetylation of peptidyl-threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071032", "l": "nuclear mRNA surveillance of mRNP export", "d": ["The set of processes involved in identifying and degrading incorrectly formed or aberrant nuclear mRNPs docked at the nuclear pore complex prior to export to the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.345706059805423", "identifiers": [{"i": "GO:1901137", "l": "carbohydrate derivative biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of carbohydrate derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900215", "l": "negative regulation of apoptotic process involved in metanephric collecting duct development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900639", "l": "positive regulation of asperfuranone biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of asperfuranone biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033377", "l": "maintenance of protein location in T cell secretory granule", "d": ["A process in which a protein is maintained in a secretory granule in a T cell and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090531", "l": "L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose", "d": ["The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate GDP-alpha-D-mannose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033487", "l": "pelargonidin 3-O-glucoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pelargonidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000719", "l": "negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0043372", "l": "positive regulation of CD4-positive, alpha-beta T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052110", "l": "occlusion by symbiont of host vascular system", "d": ["The process in which an organism reduces the flow of fluid within its host's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000175", "l": "negative regulation of pro-T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0051541", "l": "elastin metabolic process", "d": ["The chemical reactions and pathways involving elastin, a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.062480095235458", "identifiers": [{"i": "GO:0030323", "l": "respiratory tube development", "d": ["The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033121", "l": "regulation of purine nucleotide catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003428", "l": "chondrocyte intercalation involved in growth plate cartilage morphogenesis", "d": ["The orderly movement of a chondrocyte from one site to another that contributes to the shaping of growth plate cartilage in an endochondral bone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021668", "l": "rhombomere 6 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 6. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006189", "l": "'de novo' IMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0003266", "l": "regulation of secondary heart field cardioblast proliferation", "d": ["Any process that modulates the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048484", "l": "enteric nervous system development", "d": ["The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gallbladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901277", "l": "tartrate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tartrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901928", "l": "cadinene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cadinene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019595", "l": "non-phosphorylated glucose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of non-phosphorylated forms of glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046210", "l": "nitric oxide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042691", "l": "positive regulation of crystal cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of crystal cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070241", "l": "positive regulation of activated T cell autonomous cell death", "d": ["Any process that activates or increases the frequency, rate or extent of activated T cell autonomous cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140717", "l": "entry into host through the stromata", "d": ["Entry of a symbiont into host plant tissue via the stromata, microscopic pores in the epidermis of the aerial parts of terrestrial plants. These pores are essential for photosynthesis, as they allow CO2 to diffuse into the plant. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097166", "l": "lens epithelial cell proliferation", "d": ["The multiplication or reproduction of lens epithelial cells, resulting in the expansion of a cell population. Lens epithelial cells make up the lens epithelium, which is located in the anterior portion of the lens between the lens capsule and the lens fibers and is a simple cuboidal epithelium. The epithelial cells of the lens regulate most of the homeostatic functions of the lens such as osmolarity and liquid volume. The lens epithelial cells also serve as the progenitors for new lens fibers. The lens epithelium constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000858", "l": "regulation of aldosterone secretion", "d": ["Any process that modulates the frequency, rate or extent of aldosterone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0001771", "l": "immunological synapse formation", "d": ["The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902460", "l": "regulation of mesenchymal stem cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0016577", "l": "histone demethylation", "d": ["The modification of histones by removal of methyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061270", "l": "mesonephric intraglomerular mesangial cell proliferation", "d": ["The multiplication or reproduction of intraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0032652", "l": "regulation of interleukin-1 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-1 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033349", "l": "apiose metabolic process", "d": ["The chemical reactions and pathways involving apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0007308", "l": "oocyte construction", "d": ["The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903084", "l": "protein localization to condensed nuclear chromosome", "d": ["A process in which a protein is transported to, or maintained in, a location within a condensed nuclear chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990403", "l": "embryonic brain development", "d": ["The process occurring during the embryonic phase whose specific outcome is the progression of the brain over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014814", "l": "axon regeneration at neuromuscular junction", "d": ["The regrowth of axons following their loss or damage at the neuromuscular junction. Motor axons regenerate after injury and they form neuro-muscular junctions with skeletal myofibers similar to normal ones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060956", "l": "endocardial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0060419", "l": "heart growth", "d": ["The increase in size or mass of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904234", "l": "positive regulation of aconitate hydratase activity", "d": ["Any process that activates or increases the frequency, rate or extent of aconitate hydratase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901167", "l": "3-chlorocatechol metabolic process", "d": ["The chemical reactions and pathways involving 3-chlorocatechol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0006369", "l": "termination of RNA polymerase II transcription", "d": ["A transcription termination process that completes the production of a primary RNA polymerase II transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902994", "l": "regulation of phospholipid efflux", "d": ["Any process that modulates the frequency, rate or extent of phospholipid efflux."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061782", "l": "vesicle fusion with vesicle", "d": ["Fusion of the membrane of a transport vesicle with a target membrane on another vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051755", "l": "meiotic sister chromatid arm separation", "d": ["The cell cycle process in which sister chromatid arms are physically detached from each other during meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075508", "l": "entry of viral genome into host nucleus via retainment of capsid in nuclear pore complex and release of genome into nucleoplasm", "d": ["Viral penetration into the host nucleus where a viral capsid enters the host nuclear pore complex (NPC) but remains attached to the pore on the nuclear side. The capsid then disassembles, releasing the viral genome into the nucleoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901815", "l": "astaxanthin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of astaxanthin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090528", "l": "smooth septate junction assembly", "d": ["The assembly of a smooth septate junction, a septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003285", "l": "septum secundum development", "d": ["The progression of the septum secundum over time, from its initial formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903300", "l": "negative regulation of hexokinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hexokinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900136", "l": "regulation of chemokine activity", "d": ["Any process that modulates the frequency, rate or extent of chemokine activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150142", "l": "positive regulation of CD86 production", "d": ["Any process that activates or increases the frequency, rate or extent of CD86 biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900595", "l": "(+)-kotanin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (+)-kotanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0030219", "l": "megakaryocyte differentiation", "d": ["The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0071398", "l": "cellular response to fatty acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046444", "l": "FMN metabolic process", "d": ["The chemical reactions and pathways involving FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044398", "l": "envenomation resulting in induction of edema in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the swelling of soft tissues of the bitten organism as a result of excess water accumulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061484", "l": "hematopoietic stem cell homeostasis", "d": ["Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0050993", "l": "dimethylallyl diphosphate metabolic process", "d": ["The chemical reactions and pathways involving dimethylallyl diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903803", "l": "L-glutamine import across plasma membrane", "d": ["The directed movement of L-glutamine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030953", "l": "astral microtubule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of astral microtubules, any of the spindle microtubules that radiate in all directions from the spindle poles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.7920354431539", "identifiers": [{"i": "GO:0016570", "l": "histone modification", "d": ["The covalent alteration of one or more amino acid residues within a histone protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035277", "l": "spiracle morphogenesis, open tracheal system", "d": ["The process in which the anatomical structures of a spiracle are generated and organized. Spiracles are the openings in the insect open tracheal system; externally they connect to the epidermis and internally they connect to the tracheal trunk."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007446", "l": "imaginal disc growth", "d": ["The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990764", "l": "myofibroblast contraction", "d": ["The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a myofibroblast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0000920", "l": "septum digestion after cytokinesis", "d": ["The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000434", "l": "carbon catabolite repression of transcription from RNA polymerase II promoter by galactose", "d": ["Any process involving galactose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061415", "l": "negative regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source", "d": ["A transcription regulation process in which the presence of a nonfermentable carbon source leads to a decrease of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043415", "l": "positive regulation of skeletal muscle tissue regeneration", "d": ["Any process that activates or increase the rate of skeletal muscle regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071799", "l": "cellular response to prostaglandin D stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098995", "l": "disruption by virus of host envelope lipopolysaccharide during virus entry", "d": ["The breakdown of lipopolysaccharides in a host cell envelope during virus entry into a host cell. For example a phage entering a gram-negative bacterium may actively break down outer membrane lipopolysaccharides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.378002841413903", "identifiers": [{"i": "GO:0062013", "l": "positive regulation of small molecule metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900230", "l": "positive regulation of single-species biofilm formation in or on host organism", "d": ["Any process that activates or increases the frequency, rate or extent of single-species biofilm formation in or on host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003265", "l": "regulation of primary heart field cardioblast proliferation", "d": ["Any process that modulates the frequency, rate or extent of cardioblast proliferation in the primary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. In mammals the primary heart field gives rise to the left ventricle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042198", "l": "nylon metabolic process", "d": ["The chemical reactions and pathways involving nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072732", "l": "cellular response to calcium ion starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of calcium ions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018165", "l": "peptidyl-tyrosine uridylylation", "d": ["The uridylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-uridine)-L-tyrosine, found in glutamine synthetase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:0034755", "l": "iron ion transmembrane transport", "d": ["A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046598", "l": "positive regulation of viral entry into host cell", "d": ["Any process that activates or increases the frequency, rate or extent of the introduction of viral entry into the host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140569", "l": "extraction of mislocalized protein from ER membrane", "d": ["The removal of a mislocalized protein from the endoplasmic reticulum (ER) membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120310", "l": "amastigogenesis", "d": ["The morphological, biochemical and genetic changes that induce the differentiation of metacyclic parasites into amastigotes in some of the Trypanosomatidae species such as Leishmania parasites and Trypanosoma cruzi. This process occurs inside the cells of the mammalian hosts, particularly in macrophages and other phagocytic cells for Leishmania parasites."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903884", "l": "regulation of chemokine (C-C motif) ligand 20 production", "d": ["Any process that modulates the frequency, rate or extent of chemokine (C-C motif) ligand 20 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.257531776866248", "identifiers": [{"i": "GO:0008152", "l": "metabolic process", "d": ["The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071000", "l": "response to magnetism", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903749", "l": "positive regulation of establishment of protein localization to mitochondrion", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of protein localization to mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0046928", "l": "regulation of neurotransmitter secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.053789595961774", "identifiers": [{"i": "GO:1903825", "l": "organic acid transmembrane transport", "d": ["The process in which an organic acid is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051715", "l": "cytolysis in another organism", "d": ["The killing by an organism of a cell in another organism by means of the rupture of cell membranes and the loss of cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901102", "l": "gramicidin S catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of gramicidin S."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0055021", "l": "regulation of cardiac muscle tissue growth", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0097028", "l": "dendritic cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075323", "l": "positive regulation of oomycete sporangium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007463", "l": "R2/R5 cell fate commitment", "d": ["The process in which the R2/R5 photoreceptors commit to their cell fate. R2 and R5 are paired photoreceptors which contribute the outer rhabdomeres."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036378", "l": "calcitriol biosynthetic process from calciol", "d": ["Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021893", "l": "cerebral cortex GABAergic interneuron fate commitment", "d": ["The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into a GABAergic interneuron residing in the cerebral cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900849", "l": "regulation of pseurotin A biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of pseurotin A biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905541", "l": "regulation of L-arginine import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of L-arginine import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003152", "l": "morphogenesis of an epithelial fold involved in embryonic heart tube formation", "d": ["The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.06379513530257", "identifiers": [{"i": "GO:0051168", "l": "nuclear export", "d": ["The directed movement of substances out of the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905401", "l": "positive regulation of activated CD4-positive, alpha-beta T cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060436", "l": "bronchiole morphogenesis", "d": ["The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061381", "l": "cell migration in diencephalon", "d": ["The orderly movement of a cell that will reside in the diencephalon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042209", "l": "orcinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:0072396", "l": "response to cell cycle checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of cell cycle checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052653", "l": "3',5'-cyclic diguanylic acid metabolic process", "d": ["The chemical reactions and pathways involving 3',5'-cyclic diguanylic acid, a cyclic purine dinucleotide in which the base groups are guanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903658", "l": "positive regulation of type IV pilus biogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of type IV pilus biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046324", "l": "regulation of glucose import", "d": ["Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.523981342372721", "identifiers": [{"i": "GO:0032386", "l": "regulation of intracellular transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of substances within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120314", "l": "negative regulation of oocyte karyosome formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0007556", "l": "regulation of juvenile hormone metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019367", "l": "fatty acid elongation, saturated fatty acid", "d": ["Elongation of a saturated fatty acid chain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900329", "l": "positive regulation of mannotriose transport", "d": ["Any process that activates or increases the frequency, rate or extent of mannotriose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0043213", "l": "bacteriocin transport", "d": ["The directed movement of a bacteriocin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Bacteriocins are a group of antibiotics produced by bacteria and are encoded by a group of naturally occurring plasmids, e.g. Col E1. Bacteriocins are toxic to bacteria closely related to the bacteriocin producing strain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048291", "l": "isotype switching to IgG isotypes", "d": ["The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042415", "l": "norepinephrine metabolic process", "d": ["The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090209", "l": "negative regulation of triglyceride metabolic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902016", "l": "poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.32568854542945", "identifiers": [{"i": "GO:0007589", "l": "body fluid secretion", "d": ["The controlled release of a fluid by a cell or tissue in an animal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0051851", "l": "modulation by host of symbiont process", "d": ["The process in which an organism effects a change in the structure or processes of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044361", "l": "negative regulation of voltage-gated potassium channel activity in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901466", "l": "regulation of ferulate catabolic process", "d": ["Any process that modulates the frequency, rate or extent of ferulate catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:0019400", "l": "alditol metabolic process", "d": ["The chemical reactions and pathways involving alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902432", "l": "protein localization to division septum", "d": ["A process in which a protein is transported to, or maintained in, a location within a division septum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046041", "l": "ITP metabolic process", "d": ["The chemical reactions and pathways involving ITP, inosine triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036258", "l": "multivesicular body assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903939", "l": "regulation of TORC2 signaling", "d": ["Any process that modulates the frequency, rate or extent of TORC2 signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061220", "l": "mesonephric macula densa development", "d": ["The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034344", "l": "regulation of type III interferon production", "d": ["Any process that modulates the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0008037", "l": "cell recognition", "d": ["The process in which a cell in an organism interprets its surroundings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019353", "l": "protoporphyrinogen IX biosynthetic process from glutamate", "d": ["The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glutamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090259", "l": "regulation of retinal ganglion cell axon guidance", "d": ["Any process that modulates the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002900", "l": "positive regulation of central B cell deletion", "d": ["Any process that activates or increases the frequency, rate, or extent of central B cell deletion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905003", "l": "picolinic acid metabolic process", "d": ["The chemical reactions and pathways involving picolinic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033389", "l": "putrescine biosynthetic process from arginine, using agmatinase", "d": ["The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in a single enzymatic step."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044179", "l": "hemolysis in another organism", "d": ["The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905887", "l": "autoinducer AI-2 transmembrane transport", "d": ["The process in which (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol (autoinducer AI-2) is transported across a membrane. AI-2 is produced by prokaryotes and is believed to play a role in quorum sensing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002749", "l": "antigen processing and presentation initiated by toll-like receptor mediated phagocytosis of antigen", "d": ["Antigen processing and presentation which is initiated by phagocytosis of antigen bound directly or indirectly to a cell surface toll-like receptor (TLR)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904041", "l": "regulation of cystathionine beta-synthase activity", "d": ["Any process that modulates the frequency, rate or extent of cystathionine beta-synthase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010234", "l": "anther wall tapetum cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a tapetal cell of anthers in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902856", "l": "negative regulation of non-motile cilium assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of non-motile cilium assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0110003", "l": "regulation of tRNA C5-cytosine methylation", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA C5-cytosine methylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:1901656", "l": "glycoside transport", "d": ["The directed movement of a glycoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0010830", "l": "regulation of myotube differentiation", "d": ["Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904674", "l": "positive regulation of somatic stem cell population maintenance", "d": ["Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0065005", "l": "protein-lipid complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins and lipids to form a protein-lipid complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905260", "l": "positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021720", "l": "superior olivary nucleus formation", "d": ["The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.651716354923636", "identifiers": [{"i": "GO:0070848", "l": "response to growth factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900824", "l": "positive regulation of ergot alkaloid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ergot alkaloid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001058", "l": "D-tagatose 6-phosphate metabolic process", "d": ["The chemical reactions and pathways involving a D-tagatose 6-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0060491", "l": "regulation of cell projection assembly", "d": ["Any process that modulates the rate, frequency, or extent of cell projection assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060533", "l": "bronchus cartilage morphogenesis", "d": ["The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.021355091518231", "identifiers": [{"i": "GO:0044770", "l": "cell cycle phase transition", "d": ["The cell cycle process by which a cell commits to entering the next cell cycle phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043154", "l": "negative regulation of cysteine-type endopeptidase activity involved in apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019286", "l": "glycine betaine biosynthetic process from glycine", "d": ["The chemical reactions and pathways resulting in the formation of glycine betaine from other compounds, including glycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033308", "l": "hydroxyectoine transport", "d": ["The directed movement of hydroxyectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904411", "l": "positive regulation of secretory granule organization", "d": ["Any process that activates or increases the frequency, rate or extent of secretory granule organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900030", "l": "regulation of pectin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of pectin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0090357", "l": "regulation of tryptophan metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904296", "l": "negative regulation of osmolarity-sensing cation channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of osmolarity-sensing cation channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090299", "l": "regulation of neural crest formation", "d": ["Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019277", "l": "UDP-N-acetylgalactosamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036101", "l": "leukotriene B4 catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061964", "l": "negative regulation of entry into reproductive diapause", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002051", "l": "osteoblast fate commitment", "d": ["The commitment of mesenchymal cells to the specific cell fate of an osteoblast. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010068", "l": "protoderm histogenesis", "d": ["The formation of the primary meristem or meristematic tissue that gives rise to the epidermis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072054", "l": "renal outer medulla development", "d": ["The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900740", "l": "positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032730", "l": "positive regulation of interleukin-1 alpha production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-1 alpha production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.871888620241165", "identifiers": [{"i": "GO:0034502", "l": "protein localization to chromosome", "d": ["Any process in which a protein is transported to, or maintained at, a specific location on a chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015792", "l": "arabinitol transmembrane transport", "d": ["The process in which arabitol is transported across a lipid bilayer, from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.594043123901756", "identifiers": [{"i": "GO:0031330", "l": "negative regulation of cellular catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0048895", "l": "lateral line nerve glial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a glial cell in a lateral line nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120066", "l": "pyloric canal smooth muscle contraction", "d": ["A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal part of the pylorus between the pyloric antrum and the pyloric sphincter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098582", "l": "innate vocalization behavior", "d": ["A vocalisation behavior that is innate, i.e. that does not need to be learned in order to occur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0010893", "l": "positive regulation of steroid biosynthetic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033086", "l": "negative regulation of extrathymic T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of extrathymic T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003381", "l": "epithelial cell morphogenesis involved in gastrulation", "d": ["The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0006012", "l": "galactose metabolic process", "d": ["The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904108", "l": "protein localization to ciliary inversin compartment", "d": ["A process in which a protein is transported to, or maintained in, a location within a ciliary inversin compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031954", "l": "positive regulation of protein autophosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030704", "l": "vitelline membrane formation", "d": ["Construction of the vitelline membrane portion of the egg shell, a rigid structure required to maintain the shape of the egg."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090032", "l": "negative regulation of steroid hormone biosynthetic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010207", "l": "photosystem II assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a photosystem II complex on the thylakoid membrane. The photosystem II complex consists of at least 20 polypeptides and around 80 cofactors in most organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:1903467", "l": "negative regulation of mitotic DNA replication initiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048927", "l": "posterior lateral line neuromast support cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0042160", "l": "lipoprotein modification", "d": ["The chemical reactions and pathways resulting in the covalent alteration of one or more amino acid or lipid residues occurring in a lipoprotein, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019478", "l": "D-amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-amino acids, the D-enantiomers of amino acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048649", "l": "caste determination, influence by genetic factors", "d": ["The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071333", "l": "cellular response to glucose stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035264", "l": "multicellular organism growth", "d": ["The increase in size or mass of an entire multicellular organism, as opposed to cell growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060721", "l": "regulation of spongiotrophoblast cell proliferation", "d": ["Any process that modulates the rate, frequency or extent of spongiotrophoblast cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2001307", "l": "xanthone-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a xanthone-containing compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032463", "l": "negative regulation of protein homooligomerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of protein homooligomerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902070", "l": "positive regulation of sphingolipid mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of sphingolipid signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099048", "l": "CRISPR-cas system", "d": ["A defense response of that serves to clear host cells of foreign DNA and RNA. It has three distinct stage: acquisition of foreign DNA by integration into CRISPR loci in the host chromosome, CRISPR RNA (crRNA) biogenesis, and target interference. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeat, which describes the nature of the loci."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035440", "l": "tuberculosinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tuberculosinol (halima-5,6,dien-15-ol), a secondary metabolite in Mycobacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002334", "l": "transitional two stage B cell differentiation", "d": ["The process in which immature B cells from the bone marrow acquire the specialized features of T2 stage B cells in the spleen. T2 stage B cells express CD23 but not CD21."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009229", "l": "thiamine diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1990009", "l": "retinal cell apoptotic process", "d": ["Any apoptotic process in a retinal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.824318789188837", "identifiers": [{"i": "GO:0072376", "l": "protein activation cascade", "d": ["A sequential series of modifications to a set of proteins where the product of one reaction catalyzes the following reaction, ultimately leading to the generation of a mature protein. Modifications typically include proteolysis or covalent modification, and may also include binding events."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090431", "l": "alkyl caffeate ester biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ester derivatives of alkyl caffeate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0034113", "l": "heterotypic cell-cell adhesion", "d": ["The attachment of a cell to a cell of a different type via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019283", "l": "L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine", "d": ["The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including O-phospho-L-homoserine and cystathionine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0099538", "l": "synaptic signaling via neuropeptide", "d": ["Cell-cell signaling to or from a synapse, mediated by a peptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000706", "l": "negative regulation of dense core granule biogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900234", "l": "regulation of Kit signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of Kit signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014898", "l": "cardiac muscle hypertrophy in response to stress", "d": ["The physiological enlargement or overgrowth of all or part of the heart muscle due to an increase in size (not length) of individual cardiac muscle fibers, without cell division, as a result of a disturbance in organismal or cellular homeostasis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902124", "l": "(+)-pinoresinol metabolic process", "d": ["The chemical reactions and pathways involving (+)-pinoresinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0045727", "l": "positive regulation of translation", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018359", "l": "protein-heme P460 linkage via heme P460-bis-L-cysteine-L-tyrosine", "d": ["The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042343", "l": "indole glucosinolate metabolic process", "d": ["The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances based on 2,3-benzopyrrole, formed during the catabolism of tryptophan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061705", "l": "sucrose catabolic process to fructose-6-phosphate through glucose and fructose", "d": ["The chemical reactions and pathways resulting in the breakdown of sucrose, to yield fructose-6-phosphate through both glucose and fructose intermediates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:2001235", "l": "positive regulation of apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052131", "l": "positive aerotaxis", "d": ["The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072751", "l": "cellular response to L-thialysine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904345", "l": "negative regulation of gastric mucosal blood circulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1905939", "l": "regulation of gonad development", "d": ["Any process that modulates the frequency, rate or extent of gonad development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010119", "l": "regulation of stomatal movement", "d": ["Any process that modulates the frequency, rate or extent of stomatal movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901428", "l": "regulation of syringal lignin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of syringal lignin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903681", "l": "regulation of epithelial cell-cell adhesion involved in epithelium migration", "d": ["Any process that modulates the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010724", "l": "regulation of definitive erythrocyte differentiation", "d": ["Any process that modulates the rate, frequency, or extent of definitive erythrocyte differentiation. Definitive erythrocyte differentiation occurs as part of the process of definitive hemopoiesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003090", "l": "positive regulation of the force of heart contraction by neuronal epinephrine-norepinephrine", "d": ["Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine released from the nerve endings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901975", "l": "glycerate transmembrane transport", "d": ["The process in which glycerate is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902727", "l": "negative regulation of growth factor dependent skeletal muscle satellite cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902362", "l": "melanocyte apoptotic process", "d": ["Any apoptotic process in a melanocyte, the main structural component of the epidermis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0043945", "l": "positive regulation of asexual sporulation resulting in formation of a cellular spore", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900558", "l": "austinol metabolic process", "d": ["The chemical reactions and pathways involving austinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032457", "l": "fast endocytic recycling", "d": ["The directed movement of membrane-bounded vesicles from peripheral endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:1903475", "l": "mitotic actomyosin contractile ring assembly", "d": ["Any actomyosin contractile ring assembly that is involved in mitotic cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000931", "l": "negative regulation of cellobiose metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036215", "l": "response to stem cell factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031587", "l": "positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036227", "l": "mitotic G2 cell cycle arrest in response to glucose starvation", "d": ["The process in which the mitotic cell cycle is halted during G2 phase as a result of deprivation of glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018415", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide", "d": ["The incorporation of iron into a 3Fe-2S cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901347", "l": "negative regulation of secondary cell wall biogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell wall biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010793", "l": "regulation of mRNA export from nucleus", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0032722", "l": "positive regulation of chemokine production", "d": ["Any process that activates or increases the frequency, rate, or extent of chemokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060613", "l": "fat pad development", "d": ["The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900168", "l": "positive regulation of glial cell-derived neurotrophic factor production", "d": ["Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021979", "l": "hypothalamus cell differentiation", "d": ["The differentiation of cells that will contribute to the structure and function of the hypothalamus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030238", "l": "male sex determination", "d": ["The specification of male sex of an individual organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0044277", "l": "cell wall disassembly", "d": ["A process that results in the breakdown of the cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032701", "l": "negative regulation of interleukin-18 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.193892402340154", "identifiers": [{"i": "GO:0010001", "l": "glial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031509", "l": "subtelomeric heterochromatin formation", "d": ["The compaction of chromatin into heterochromatin at the subtelomeric region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015962", "l": "diadenosine triphosphate metabolic process", "d": ["The chemical reactions and pathways involving diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0010310", "l": "regulation of hydrogen peroxide metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0071560", "l": "cellular response to transforming growth factor beta stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:2000816", "l": "negative regulation of mitotic sister chromatid separation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid separation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:2001088", "l": "trisaccharide transport", "d": ["The directed movement of a trisaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060870", "l": "cell wall disassembly involved in floral organ abscission", "d": ["A cellular process that results in the breakdown of the cell wall that contributes to the process of floral organ abscission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.398694714732429", "identifiers": [{"i": "GO:0010648", "l": "negative regulation of cell communication", "d": ["Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0003307", "l": "regulation of Wnt signaling pathway involved in heart development", "d": ["Any process that modulates the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061263", "l": "mesonephric glomerular mesangial cell development", "d": ["The process whose specific outcome is the progression of a glomerular mesangial cell in the mesonephros over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001813", "l": "regulation of antibody-dependent cellular cytotoxicity", "d": ["Any process that modulates the frequency, rate, or extent of antibody-dependent cellular cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0034050", "l": "programmed cell death induced by symbiont", "d": ["Cell death resulting from activation of endogenous cellular processes after interaction with a symbiont (defined as the smaller of two, or more, organisms engaged in symbiosis, a close interaction encompassing mutualism through parasitism). This can be triggered by direct interaction with the organism, for example, contact with penetrating hyphae of a fungus; or an indirect interaction such as symbiont-secreted molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0055011", "l": "atrial cardiac muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a cardiac muscle cell in the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000501", "l": "regulation of natural killer cell chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of natural killer cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0039656", "l": "modulation by virus of host gene expression", "d": ["The process in which a virus effects a change in gene expression in its host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032307", "l": "negative regulation of prostaglandin secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a prostaglandin from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0050914", "l": "sensory perception of salty taste", "d": ["The series of events required to receive a salty taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075135", "l": "disruption of host calcium or calmodulin-mediated signal transduction", "d": ["Any process in which the symbiont organism interferes with calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0016059", "l": "deactivation of rhodopsin mediated signaling", "d": ["The process of restoring the photoreceptor cell to its unexcited state after termination of the stimulus (photon)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0031640", "l": "killing of cells of another organism", "d": ["Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034120", "l": "positive regulation of erythrocyte aggregation", "d": ["Any process that activates or increases the frequency, rate, or extent of erythrocyte aggregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120116", "l": "glucagon processing", "d": ["The formation of mature glucagon by proteolysis of the precursor proglucagon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050830", "l": "defense response to Gram-positive bacterium", "d": ["Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0007300", "l": "ovarian nurse cell to oocyte transport", "d": ["Transfer of constituents synthesized in the ovarian nurse cells to the oocyte, through the ring canals, as the egg chamber is growing. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009294", "l": "DNA-mediated transformation", "d": ["The direct uptake and incorporation of exogenous genetic material (DNA or RNA) into a cell from its surroundings through the cell envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000705", "l": "achiasmate meiosis I", "d": ["The first division of meiosis in which homologous chromosomes are paired and segregated from each other, occurring in the constitutive absence of chiasmata."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.474657494018913", "identifiers": [{"i": "GO:0001823", "l": "mesonephros development", "d": ["The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140710", "l": "regulation of Frizzled Nuclear Import pathway", "d": ["Any process that modulates the frequency, rate or extent of a Frizzled Nuclear Import pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900671", "l": "negative regulation of F-9775A biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of F-9775A biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901794", "l": "3-(3-hydroxyphenyl)propanoate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxyphenyl)propanoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048838", "l": "release of seed from dormancy", "d": ["The process in which the dormant state is broken in a seed. Dormancy is characterized by a suspension of physiological activity that can be reactivated upon release."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046874", "l": "quinolinate metabolic process", "d": ["The chemical reactions and pathways involving quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0003415", "l": "chondrocyte hypertrophy", "d": ["The growth of a chondrocyte, where growth contributes to the progression of the chondrocyte over time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0032434", "l": "regulation of proteasomal ubiquitin-dependent protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034510", "l": "centromere separation", "d": ["The cell cycle process in which centromeres are physically detached from each other during chromosome separation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902722", "l": "positive regulation of prolactin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of prolactin secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140203", "l": "spermidine import across plasma membrane", "d": ["The directed movement of spermidine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002525", "l": "acute inflammatory response to non-antigenic stimulus", "d": ["An acute inflammatory response to non-antigenic stimuli such as heat or physical trauma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150153", "l": "positive regulation of interleukin-17A production", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-17A production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061706", "l": "glycolytic process from sucrose through glucose and fructose", "d": ["The chemical reactions and pathways resulting in the breakdown of sucrose into pyruvate through both glucose and fructose intermediates, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035193", "l": "larval central nervous system remodeling", "d": ["Reorganization of the pre-existing, functional larval central nervous system into one that can serve the novel behavioral needs of the adult. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902474", "l": "positive regulation of protein localization to synapse", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045692", "l": "negative regulation of embryo sac central cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac central cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904839", "l": "negative regulation of male germ-line stem cell asymmetric division", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of male germ-line stem cell asymmetric division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905176", "l": "positive regulation of vascular associated smooth muscle cell dedifferentiation", "d": ["Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell dedifferentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904272", "l": "L-tryptophan import across plasma membrane", "d": ["The directed movement of L-tryptophan from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903340", "l": "positive regulation of cell wall organization or biogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cell wall organization or biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902681", "l": "regulation of replication fork arrest at rDNA repeats", "d": ["Any process that modulates the frequency, rate or extent of replication fork arrest at rDNA repeats."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009246", "l": "enterobacterial common antigen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0034497", "l": "protein localization to phagophore assembly site", "d": ["Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010630", "l": "regulation of transcription, start site selection", "d": ["Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA by a mechanism that selects the start site along that template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032290", "l": "peripheral nervous system myelin formation", "d": ["The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007474", "l": "imaginal disc-derived wing vein specification", "d": ["The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0044379", "l": "protein localization to actin cortical patch", "d": ["A process in which a protein is transported to, or maintained in, an actin cortical patch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072718", "l": "response to cisplatin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900319", "l": "negative regulation of methane biosynthetic process from dimethylamine", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072305", "l": "negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis", "d": ["Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010612", "l": "regulation of cardiac muscle adaptation", "d": ["Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.398664172980133", "identifiers": [{"i": "GO:0060627", "l": "regulation of vesicle-mediated transport", "d": ["Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.000891501185137", "identifiers": [{"i": "GO:0060537", "l": "muscle tissue development", "d": ["The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1904861", "l": "excitatory synapse assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0140121", "l": "Lewy body formation", "d": ["The aggregation, arrangement and bonding together of a set of components to form a Lewy body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002259", "l": "endothelial cell activation within high endothelial venule involved in immune response", "d": ["A change in the morphology or behavior of an endothelial cell within a high endothelial venule resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110076", "l": "negative regulation of ferroptosis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ferroptosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903294", "l": "regulation of glutamate secretion, neurotransmission", "d": ["Any process that modulates the frequency, rate or extent of glutamate secretion, neurotransmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099588", "l": "positive regulation of postsynaptic cytosolic calcium concentration", "d": ["Any process that increases the concentration of calcium ions in the postsynaptic cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000383", "l": "regulation of ectoderm development", "d": ["Any process that modulates the frequency, rate or extent of ectoderm development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0051350", "l": "negative regulation of lyase activity", "d": ["Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017199", "l": "N-terminal peptidyl-threonine acetylation", "d": ["The acetylation of the N-terminal threonine of proteins to form the derivative N-acetyl-L-threonine; catalyzed by peptide alpha-N-acetyltransferase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.364943696244829", "identifiers": [{"i": "GO:0032880", "l": "regulation of protein localization", "d": ["Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0019614", "l": "catechol-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036001", "l": "'de novo' pyridoxal 5'-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyridoxal 5'-phosphate, the active form of vitamin B6, from simpler components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071409", "l": "cellular response to cycloheximide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051356", "l": "visual perception involved in equilibrioception", "d": ["The series of events during equilibrioception required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual input plays an important role in the ability of an organism to perceive its orientation with respect to gravity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903850", "l": "regulation of cristae formation", "d": ["Any process that modulates the frequency, rate or extent of cristae formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0002384", "l": "hepatic immune response", "d": ["An immune response taking place in the liver."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902085", "l": "fumagillin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fumagillin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000205", "l": "positive regulation of ribosomal large subunit export from nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of ribosomal large subunit export from nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046044", "l": "TMP metabolic process", "d": ["The chemical reactions and pathways involving TMP, ribosylthymine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140712", "l": "negative regulation of Frizzled Nuclear Import pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a Frizzled Nuclear Import pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.72235522081229", "identifiers": [{"i": "GO:0098657", "l": "import into cell", "d": ["The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990854", "l": "vacuole-ER tethering", "d": ["The attachment of a lytic vacuole to the endoplasmic reticulum, which may facilitate exchange of metabolites between the organelles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904446", "l": "positive regulation of establishment of Sertoli cell barrier", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of Sertoli cell barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061589", "l": "calcium activated phosphatidylserine scrambling", "d": ["The movement of a population of phosphatidylserine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051158", "l": "L-arabitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046621", "l": "negative regulation of organ growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061857", "l": "endoplasmic reticulum stress-induced pre-emptive quality control", "d": ["The response to endoplasimic reticulum stress in which nascent proteins are degraded by attenuation of their translocation into the ER followed by rerouting to the cytosol without cleavage of the signal peptide, and subsequent degradation by the proteasome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018953", "l": "p-cymene metabolic process", "d": ["The chemical reactions and pathways involving p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010266", "l": "response to vitamin B1", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120042", "l": "negative regulation of macrophage proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071244", "l": "cellular response to carbon dioxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110023", "l": "negative regulation of cardiac muscle myoblast proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090064", "l": "activation of microtubule nucleation", "d": ["Any process that starts the inactive process of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0021548", "l": "pons development", "d": ["The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010371", "l": "regulation of gibberellin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0055092", "l": "sterol homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of sterol within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032581", "l": "ER-dependent peroxisome organization", "d": ["A process of peroxisome organization in which assembly or arrangement of constituent parts takes place in the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071603", "l": "endothelial cell-cell adhesion", "d": ["The attachment of an endothelial cell to another endothelial cell via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060044", "l": "negative regulation of cardiac muscle cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000225", "l": "negative regulation of testosterone biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of testosterone biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009203", "l": "ribonucleoside triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002270", "l": "plasmacytoid dendritic cell activation", "d": ["A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031173", "l": "otolith mineralization completed early in development", "d": ["The formation of otoliths during embryogenesis with completion in early postembryonic development. Formation occurs by precipitation of specific crystal forms of calcium carbonate around an organic core of extracellular matrix proteins. Otoconia (otoliths) are small (~10 micron) dense extracellular particles present in the otolith end organs of the vertebrate inner ear."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0034472", "l": "snRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of an snRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060809", "l": "mesodermal to mesenchymal transition involved in gastrulation", "d": ["The epithelial to mesenchymal transition process in which a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019374", "l": "galactolipid metabolic process", "d": ["The chemical reactions and pathways involving galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071812", "l": "positive regulation of fever generation by positive regulation of prostaglandin secretion", "d": ["Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901634", "l": "positive regulation of synaptic vesicle membrane organization", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle membrane organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.470950656012619", "identifiers": [{"i": "GO:0075136", "l": "response to host", "d": ["Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018191", "l": "peptidyl-serine octanoylation", "d": ["The octanoylation of peptidyl-serine to form peptidyl-O3-octanoyl-L-serine, typical of the protein ghrelin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0072699", "l": "protein localization to cortical microtubule cytoskeleton", "d": ["A process in which a protein is transported to, or maintained at, a location within the cortical microtubule cytoskeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072096", "l": "negative regulation of branch elongation involved in ureteric bud branching", "d": ["Any process that reduces the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140735", "l": "lovastatin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lovastatin (also known as mevinolin, mevacor or monacolin K), a hypolipidemic inhibitor of (3S)-hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1905421", "l": "regulation of plant organ morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of plant organ morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061124", "l": "positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone", "d": ["Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0075109", "l": "modulation by symbiont of host receptor-mediated signal transduction", "d": ["Any process in which the symbiont modulates the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The receptor is defined as a protein on the cell membrane or within the cytoplasm or cell nucleus that binds to a specific molecule (a ligand) such as a neurotransmitter or a hormone or other substance, and initiates the cellular response to the ligand. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.141482614631713", "identifiers": [{"i": "GO:0010628", "l": "positive regulation of gene expression", "d": ["Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000952", "l": "negative regulation of xyloglucan catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061962", "l": "negative regulation of heme oxygenase activity", "d": ["Any process that stops, prevents, or reduces the frequency or rate of heme oxygenase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0110040", "l": "pharynx morphogenesis", "d": ["The process in which the anatomical structures of the pharynx are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905239", "l": "regulation of canonical Wnt signaling pathway involved in osteoblast differentiation", "d": ["Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900903", "l": "negative regulation of hexadecanal biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990258", "l": "histone glutamine methylation", "d": ["The modification of a histone by addition of a methyl group to an glutamine residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1902103", "l": "negative regulation of metaphase/anaphase transition of meiotic cell cycle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902294", "l": "cell cycle DNA replication termination", "d": ["Any DNA replication termination that is involved in cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060218", "l": "hematopoietic stem cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061066", "l": "positive regulation of dauer larval development", "d": ["Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0019401", "l": "alditol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090114", "l": "COPII-coated vesicle budding", "d": ["The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900373", "l": "positive regulation of purine nucleotide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of purine nucleotide biosynthetic processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051004", "l": "regulation of lipoprotein lipase activity", "d": ["Any process that modulates the activity of the enzyme lipoprotein lipase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002328", "l": "pro-B cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.116918913335823", "identifiers": [{"i": "GO:0099003", "l": "vesicle-mediated transport in synapse", "d": ["Any vesicle-mediated transport that occurs in a synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0032957", "l": "inositol trisphosphate metabolic process", "d": ["The chemical reactions and pathways involving myo-inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.592623214224929", "identifiers": [{"i": "GO:0060348", "l": "bone development", "d": ["The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032531", "l": "regulation of follicle cell microvillus organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900205", "l": "apoptotic process involved in metanephric nephron tubule development", "d": ["Any apoptotic process that is involved in metanephric nephron tubule development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140406", "l": "L-alanine export across the plasma membrane", "d": ["The directed movement of L-alanine from inside of a cell, across the plasma membrane and into the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0060259", "l": "regulation of feeding behavior", "d": ["Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032968", "l": "positive regulation of transcription elongation by RNA polymerase II", "d": ["Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085017", "l": "entry into host cell by a symbiont-containing vacuole", "d": ["The invasion by a symbiont of a cell of a host organism, forming a vacuole in which the symbiont resides. The vacuole membrane is formed from lipids and proteins derived from both host and symbiont. Begins when the symbiont attaches on to the host cell membrane which invaginates and deepens as the symbiont enters, and ends when the host cell membrane closes behind the newly-formed vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060645", "l": "peripheral mammary gland bud epithelial cell differentiation", "d": ["The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an epithelial cell at the periphery of the mammary gland bud. Cells at the periphery of the bud are larger that those of the surrounding epithelium and are arranged concentrically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140916", "l": "zinc ion import into lysosome", "d": ["The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a lysosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0040019", "l": "positive regulation of embryonic development", "d": ["Any process that activates or increases the frequency, rate or extent of embryonic development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045974", "l": "regulation of translation, ncRNA-mediated", "d": ["Any process, mediated by small non-coding RNAs, that modulates the frequency, rate or extent that mRNAs are effectively translated into protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060093", "l": "negative regulation of synaptic transmission, glycinergic", "d": ["Any process that stops or decreases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0045465", "l": "R8 cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of the R8 photoreceptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039606", "l": "suppression by virus of host translation initiation", "d": ["Any process in which a virus prevents or reduces the frequency, rate or extent of host translation initiation, the host process preceding formation of the peptide bond between the first two amino acids of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002681", "l": "somatic recombination of T cell receptor gene segments", "d": ["The process in which T cell receptor genes are formed through recombination of the germline genetic elements, also known as T cell receptor gene segments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043105", "l": "negative regulation of GTP cyclohydrolase I activity", "d": ["Any process that stops or reduces the activity of the enzyme GTP cyclohydrolase I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901545", "l": "response to raffinose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042352", "l": "GDP-L-fucose salvage", "d": ["The formation of GDP-L-fucose from L-fucose, without de novo synthesis. L-fucose is phosphorylated by fucokinase and then converted by fucose-1-phosphate guanylyltransferase (EC:2.7.7.30)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990481", "l": "mRNA pseudouridine synthesis", "d": ["The intramolecular conversion of uridine to pseudouridine in an mRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0021761", "l": "limbic system development", "d": ["The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035688", "l": "T-helper 1 cell diapedesis", "d": ["The passage of a T-helper 1 cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.282738951573606", "identifiers": [{"i": "GO:0043254", "l": "regulation of protein-containing complex assembly", "d": ["Any process that modulates the frequency, rate or extent of protein complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.281967957033203", "identifiers": [{"i": "GO:0048002", "l": "antigen processing and presentation of peptide antigen", "d": ["The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.569439710577498", "identifiers": [{"i": "GO:0006633", "l": "fatty acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032821", "l": "negative regulation of natural killer cell proliferation involved in immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900286", "l": "negative regulation of cellotriose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010274", "l": "hydrotropism", "d": ["Growth or movement in a sessile organism toward or away from water, as of the roots of a plant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900931", "l": "positive regulation of L-tyrosine import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of L-tyrosine import into the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001118", "l": "tetrahydromethanopterin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a tetrahydromethanopterin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070910", "l": "cell wall macromolecule catabolic process involved in cell wall disassembly", "d": ["The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003140", "l": "determination of left/right asymmetry in lateral mesoderm", "d": ["The establishment of the lateral mesoderm with respect to the left and right halves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.980302069293842", "identifiers": [{"i": "GO:0031099", "l": "regeneration", "d": ["The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902646", "l": "regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098718", "l": "serine import across plasma membrane", "d": ["The directed movement of serine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0032594", "l": "protein transport within lipid bilayer", "d": ["The directed movement of a protein from one location to another within a lipid bilayer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902654", "l": "aromatic primary alcohol metabolic process", "d": ["The chemical reactions and pathways involving aromatic primary alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042052", "l": "rhabdomere development", "d": ["The assembly and arrangement of a rhabdomere within a cell. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097695", "l": "establishment of protein-containing complex localization to telomere", "d": ["The directed movement of a protein-containing macromolecular complex to a specific location in the telomeric region of a chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039673", "l": "evasion by virus of host dendritic cell activity", "d": ["Any process by which a virus avoids the effects mediated by the host organism's dendritic cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901033", "l": "positive regulation of response to reactive oxygen species", "d": ["Any process that activates or increases the frequency, rate or extent of response to reactive oxygen species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903444", "l": "negative regulation of brown fat cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905852", "l": "positive regulation of backward locomotion", "d": ["Any process that activates or increases the frequency, rate or extent of backward locomotion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902208", "l": "regulation of bacterial-type flagellum assembly", "d": ["Any process that modulates the frequency, rate or extent of bacterial-type flagellum assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010120", "l": "camalexin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071357", "l": "cellular response to type I interferon", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903711", "l": "spermidine transmembrane transport", "d": ["The process in which spermidine is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046387", "l": "deoxyribose 1,5-bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085020", "l": "protein K6-linked ubiquitination", "d": ["A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is added to a protein. K6-linked ubiquitination is involved in DNA repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0051625", "l": "epinephrine uptake", "d": ["The directed movement of epinephrine into a cell, typically presynaptic neurons or glial cells. Epinephrine is a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0071853", "l": "fungal-type cell wall disassembly", "d": ["A cellular process that results in the breakdown of a fungal-type cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.05504842691775", "identifiers": [{"i": "GO:0048232", "l": "male gamete generation", "d": ["Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090251", "l": "protein localization involved in establishment of planar polarity", "d": ["Any process in which a protein is transported to, and/or maintained in, a specific location in a cell that contributes to the establishment of planar polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902946", "l": "protein localization to early endosome", "d": ["A process in which a protein is transported to, or maintained in, a location within an early endosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048658", "l": "anther wall tapetum development", "d": ["The process whose specific outcome is the progression of the anther wall tapetum over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019620", "l": "aerobic benzoate metabolic process", "d": ["The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the presence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042191", "l": "methylmercury metabolic process", "d": ["The chemical reactions and pathways involving methylmercury (MeHg+), a highly toxic organometal which can accumulate in tissues, particularly in fish species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046236", "l": "mandelate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001803", "l": "regulation of type III hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of type III hypersensitivity, a type of inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900151", "l": "regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "d": ["Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048362", "l": "pedicel mucilage metabolic process", "d": ["The chemical reactions and pathways involving mucilage that occur in the flower stem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0050766", "l": "positive regulation of phagocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of phagocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099153", "l": "synaptic transmission, serotonergic", "d": ["The vesicular release of serotonin from a presynapse, across a chemical synapse, the subsequent activation of serotonin receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021572", "l": "rhombomere 6 development", "d": ["The process whose specific outcome is the progression of rhombomere 6 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0070341", "l": "fat cell proliferation", "d": ["The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0022018", "l": "lateral ganglionic eminence cell proliferation", "d": ["The multiplication or reproduction of lateral ganglionic eminence cells, resulting in the expansion of the cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0052040", "l": "modulation by symbiont of host programmed cell death", "d": ["Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990659", "l": "sequestering of manganese ion", "d": ["The process of binding or confining manganese ions such that they are separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075331", "l": "negative regulation of arbuscule formation for nutrient acquisition from host", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033356", "l": "UDP-L-arabinose metabolic process", "d": ["The chemical reactions and pathways involving UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0045830", "l": "positive regulation of isotype switching", "d": ["Any process that activates or increases the frequency, rate or extent of isotype switching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003116", "l": "regulation of vasoconstriction by norepinephrine", "d": ["Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream or released by nerve endings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900959", "l": "regulation of 17-methylnonadec-1-ene metabolic process", "d": ["Any process that modulates the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015951", "l": "purine ribonucleotide interconversion", "d": ["The chemical reactions and pathways by which a purine ribonucleotide is synthesized from another purine ribonucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901546", "l": "regulation of synaptic vesicle lumen acidification", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle lumen acidification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006425", "l": "glutaminyl-tRNA aminoacylation", "d": ["The process of coupling glutamine to glutaminyl-tRNA, catalyzed by glutaminyl-tRNA synthetase. The glutaminyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901999", "l": "homogentisate metabolic process", "d": ["The chemical reactions and pathways involving homogentisate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:2000028", "l": "regulation of photoperiodism, flowering", "d": ["Any process that modulates the frequency, rate or extent of photoperiodism, flowering."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903630", "l": "regulation of aminoacyl-tRNA ligase activity", "d": ["Any process that modulates the frequency, rate or extent of aminoacyl-tRNA ligase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903373", "l": "positive regulation of endoplasmic reticulum tubular network organization", "d": ["Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum tubular network organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033348", "l": "tetrose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019549", "l": "glutamate catabolic process to succinate via succinate semialdehyde", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the pyruvate-dependent gamma aminobutyrate (GABA) transaminase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002025", "l": "norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure", "d": ["A process that results in an increase in the diameter of an artery during the norepinephrine-epinephrine response to blood pressure change."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0015691", "l": "cadmium ion transport", "d": ["The directed movement of cadmium (Cd) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902568", "l": "positive regulation of eosinophil activation", "d": ["Any process that activates or increases the frequency, rate or extent of eosinophil activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003047", "l": "regulation of systemic arterial blood pressure by epinephrine", "d": ["The regulation of blood pressure mediated by the catecholamine signaling molecule epinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.04268446953737", "identifiers": [{"i": "GO:0001503", "l": "ossification", "d": ["The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016201", "l": "synaptic target inhibition", "d": ["The process in which a neuronal cell in a multicellular organism recognizes chemorepellent signals that inhibit its growth toward the source."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110140", "l": "flagellum attachment zone organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a flagellum attachment zone. FAZ is a network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.047418632139539", "identifiers": [{"i": "GO:0022607", "l": "cellular component assembly", "d": ["The aggregation, arrangement and bonding together of a cellular component."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060057", "l": "apoptotic process involved in mammary gland involution", "d": ["Any apoptotic process that triggers the activity of proteolytic caspases whose actions dismantle the mammary epithelial cells resulting in their programmed cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0061780", "l": "mitotic cohesin loading", "d": ["The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA as part of the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075011", "l": "positive regulation of germ tube formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0110111", "l": "negative regulation of animal organ morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990611", "l": "regulation of cytoplasmic translational initiation in response to stress", "d": ["Modulation of the frequency, rate or extent of cytoplasmic translational initiation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002581", "l": "negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150151", "l": "regulation of interleukin-17A production", "d": ["Any process that modulates the frequency, rate or extent of interleukin-17A production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0042492", "l": "gamma-delta T cell differentiation", "d": ["The process in which a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075720", "l": "establishment of episomal latency", "d": ["A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a distinct genetic entity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0021532", "l": "neural tube patterning", "d": ["The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000215", "l": "negative regulation of proline metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of proline metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0021924", "l": "cell proliferation in external granule layer", "d": ["The multiplication or reproduction of neuroblasts resulting in the expansion of a cell population in the external granule layer of the hindbrain. The external granule layer is the layer that originates from the rostral half of the rhombic lip in the first rhombomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046063", "l": "dCMP metabolic process", "d": ["The chemical reactions and pathways involving dCMP, deoxycytidine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061481", "l": "response to TNF agonist", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a TNF agonist stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010832", "l": "negative regulation of myotube differentiation", "d": ["Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018896", "l": "dibenzothiophene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901301", "l": "regulation of cargo loading into COPII-coated vesicle", "d": ["Any process that modulates the frequency, rate or extent of cargo loading into COPII-coated vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0002679", "l": "respiratory burst involved in defense response", "d": ["A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150037", "l": "regulation of calcium-dependent activation of synaptic vesicle fusion", "d": ["Any process that modulates the frequency, rate or extent of calcium-dependent activation of synaptic vesicle fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0003309", "l": "type B pancreatic cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048385", "l": "regulation of retinoic acid receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:1903707", "l": "negative regulation of hemopoiesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051162", "l": "L-arabitol metabolic process", "d": ["The chemical reactions and pathways involving L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010321", "l": "regulation of vegetative phase change", "d": ["Any process that modulates the frequency, rate or extent of vegetative phase change. Vegetative phase change is the set of post-embryonic processes involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901853", "l": "5,6,7,8-tetrahydrosarcinapterin metabolic process", "d": ["The chemical reactions and pathways involving 5,6,7,8-tetrahydrosarcinapterin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.819490397197882", "identifiers": [{"i": "GO:0006956", "l": "complement activation", "d": ["Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0032222", "l": "regulation of synaptic transmission, cholinergic", "d": ["Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0008594", "l": "photoreceptor cell morphogenesis", "d": ["The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904195", "l": "regulation of granulosa cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of granulosa cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900973", "l": "positive regulation of sarcinapterin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of sarcinapterin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0000753", "l": "cell morphogenesis involved in conjugation with cellular fusion", "d": ["The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902325", "l": "negative regulation of chlorophyll biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044658", "l": "pore formation in host plasma membrane", "d": ["The disruption of host plasma membrane integrity by formation of a pore, resulting in deregulated ion homeostasis, and cellular dysfunction that can result in cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901470", "l": "negative regulation of syringal lignin catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030711", "l": "positive regulation of border follicle cell delamination", "d": ["Any process that increases the frequency, rate or extent of border cell delamination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106044", "l": "guanine deglycation", "d": ["The removal of a sugar or dicarbonyl from a glycated guanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070489", "l": "T cell aggregation", "d": ["The adhesion of one T cell to one or more other T cells via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903622", "l": "regulation of RNA polymerase III activity", "d": ["Any process that modulates the frequency, rate or extent of RNA polymerase III activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901094", "l": "negative regulation of protein homotetramerization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein homotetramerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051331", "l": "meiotic G2 phase", "d": ["The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.686661695795102", "identifiers": [{"i": "GO:0006119", "l": "oxidative phosphorylation", "d": ["The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051628", "l": "positive regulation of epinephrine uptake", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of epinephrine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001211", "l": "negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019357", "l": "nicotinate nucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061456", "l": "mesenchymal stem cell migration involved in uteric bud morphogenesis", "d": ["The orderly movement of a mesenchymal stem cell from one site to another contributing to the shaping of the ureteric bud. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051951", "l": "positive regulation of glutamate uptake involved in transmission of nerve impulse", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009794", "l": "regulation of mitotic cell cycle, embryonic", "d": ["Any process that modulates the frequency, rate or extent of replication and segregation of genetic material in the embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003132", "l": "mesodermal-endodermal cell signaling involved in heart induction", "d": ["Any process that mediates the transfer of information from mesodermal cells to endodermal cells that contributes to heart induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035063", "l": "nuclear speck organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of nuclear specks, a class of nuclear body in which splicing factors are localized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0072189", "l": "ureter development", "d": ["The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072730", "l": "response to papulacandin B", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098700", "l": "neurotransmitter loading into synaptic vesicle", "d": ["The active transport of neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action of proton pumps."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905152", "l": "positive regulation of voltage-gated sodium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of voltage-gated sodium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035764", "l": "dorsal motor nucleus of vagus nerve formation", "d": ["The process that gives rise to the dorsal motor nucleus of the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903048", "l": "regulation of acetylcholine-gated cation channel activity", "d": ["Any process that modulates the frequency, rate or extent of acetylcholine-gated cation channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0044483", "l": "envenomation resulting in impairment of hemostasis in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the process of hemostasis - the stopping of bleeding or the arrest of the circulation to an organ or part - in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0017198", "l": "N-terminal peptidyl-serine acetylation", "d": ["The acetylation of the N-terminal serine of proteins to form the derivative N-acetyl-L-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019328", "l": "anaerobic gallate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048559", "l": "establishment of floral organ orientation", "d": ["The process that determines the orientation of the floral organs with reference to the central axis of the flower."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046361", "l": "2-oxobutyrate metabolic process", "d": ["The chemical reactions and pathways involving 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1904356", "l": "regulation of telomere maintenance via telomere lengthening", "d": ["Any process that modulates the frequency, rate or extent of telomere maintenance via telomere lengthening."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052519", "l": "positive regulation of nutrient release by symbiont", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903488", "l": "negative regulation of lactation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lactation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070246", "l": "natural killer cell apoptotic process", "d": ["Any apoptotic process in a natural killer cell, a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008635", "l": "activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c", "d": ["Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process and is mediated by cytochrome c."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0086074", "l": "Purkinje myocyte-ventricular cardiac muscle cell adhesion involved in cell communication", "d": ["The attachment of an Purkinje myocyte to a ventricular cardiac muscle cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:2000401", "l": "regulation of lymphocyte migration", "d": ["Any process that modulates the frequency, rate or extent of lymphocyte migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0001992", "l": "regulation of systemic arterial blood pressure by vasopressin", "d": ["The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140409", "l": "positive regulation of mRNA alternative polyadenylation", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA alternative polyadenylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903403", "l": "negative regulation of renal phosphate excretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of renal phosphate excretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990765", "l": "colon smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0002644", "l": "negative regulation of tolerance induction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902789", "l": "cellular response to isooctane", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0039653", "l": "suppression by virus of host transcription", "d": ["Any process in which a virus stops, prevents, or reduces the activity of host DNA-dependent transcription; the cellular synthesis of RNA on a template of DNA. Viral proteins can interfere with either host RNA polymerase or with transcription factors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903651", "l": "positive regulation of cytoplasmic transport", "d": ["Any process that activates or increases the frequency, rate or extent of cytoplasmic transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046701", "l": "insecticide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of insecticides, chemicals used to kill insects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044523", "l": "envenomation resulting in damage of muscle extracellular matrix in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, damaging the extracellular matrix of muscle cells and ultimately resulting in muscle necrosis in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0035672", "l": "oligopeptide transmembrane transport", "d": ["The process in which an oligopeptide is transported across a membrane. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097119", "l": "postsynaptic density protein 95 clustering", "d": ["The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045188", "l": "regulation of circadian sleep/wake cycle, non-REM sleep", "d": ["Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0062132", "l": "regulation of L-glutamine biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of L-glutamine biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035079", "l": "polytene chromosome puffing", "d": ["The decondensing (loosening) and swelling of the chromosomal sites of target genes on polytene chromosomes following response to a stimulus, to facilitate sudden bursts of transcriptional activity in response to transient environmental signals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010060", "l": "negative regulation of atrichoblast fate specification", "d": ["Any process that suppresses atrichoblast fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014826", "l": "vein smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the vein. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The vein is a vessel carrying blood away from the capillary beds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0086027", "l": "AV node cell to bundle of His cell signaling", "d": ["Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009733", "l": "response to auxin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051631", "l": "regulation of acetylcholine uptake", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046239", "l": "phthalate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phthalate, the anion of phthalic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090191", "l": "negative regulation of branching involved in ureteric bud morphogenesis", "d": ["Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0032986", "l": "protein-DNA complex disassembly", "d": ["The disaggregation of a protein-DNA complex into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0050671", "l": "positive regulation of lymphocyte proliferation", "d": ["Any process that activates or increases the rate or extent of lymphocyte proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "51.047156898492226", "identifiers": [{"i": "GO:0006793", "l": "phosphorus metabolic process", "d": ["The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.115092299077254", "identifiers": [{"i": "GO:0050974", "l": "detection of mechanical stimulus involved in sensory perception", "d": ["The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0022030", "l": "telencephalon glial cell migration", "d": ["The orderly movement of glial cells through the telencephalon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902256", "l": "regulation of apoptotic process involved in outflow tract morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0039665", "l": "permeabilization of host organelle membrane involved in viral entry into host cell", "d": ["Induction of organellar membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with a viral capsid. Results in release of the virus contents from an organelle into the host cell cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060522", "l": "inductive mesenchymal to epithelial cell signaling", "d": ["Signaling at short range from mesenchymal cells to cells of an epithelium that results in a developmental change in the epithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002304", "l": "gamma-delta intraepithelial T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990893", "l": "mitotic chromosome centromere condensation", "d": ["The cell cycle process in which centromere chromatin structure is compacted prior to and during mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021794", "l": "thalamus development", "d": ["The process in which the thalamus changes over time, from its initial formation to its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044760", "l": "modulation by symbiont of host cholinergic synaptic transmission", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0050798", "l": "activated T cell proliferation", "d": ["The expansion of a T cell population following activation by an antigenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903677", "l": "regulation of cap-independent translational initiation", "d": ["Any process that modulates the frequency, rate or extent of cap-independent translational initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072567", "l": "chemokine (C-X-C motif) ligand 2 production", "d": ["The appearance of chemokine (C-X-C motif) ligand 2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0106134", "l": "positive regulation of cardiac muscle cell contraction", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac muscle cell contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0043633", "l": "polyadenylation-dependent RNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3'-end of the target RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901029", "l": "negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.430588326526099", "identifiers": [{"i": "GO:0002790", "l": "peptide secretion", "d": ["The controlled release of a peptide from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0048846", "l": "axon extension involved in axon guidance", "d": ["The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099556", "l": "trans-synaptic signaling by carbon monoxide, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, via the release and reception of carbon monoxide molecules, that modulates the synaptic transmission properties of the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0097176", "l": "epoxide metabolic process", "d": ["The chemical reactions and pathways involving epoxides, compounds in which an oxygen atom is directly attached to two adjacent or non-adjacent carbon atoms of a carbon chain or ring system; thus cyclic ethers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048093", "l": "positive regulation of male pigmentation", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in males."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0060947", "l": "cardiac vascular smooth muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106101", "l": "ER-dependent peroxisome localization", "d": ["A process in which a protein is transported to, or maintained at, a location in a peroxisome via the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160035", "l": "negative regulation of Toll receptor ligand protein activation cascade", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Toll receptor ligand protein activation cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.024910309174537", "identifiers": [{"i": "GO:0042180", "l": "cellular ketone metabolic process", "d": ["The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0018974", "l": "2,4,6-trinitrotoluene metabolic process", "d": ["The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid. It is prepared from toluene treated with concentrated sulfuric and nitric acids and is used in shells, bombs, and blasting explosives."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.003741351937961", "identifiers": [{"i": "GO:0022602", "l": "ovulation cycle process", "d": ["A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0120180", "l": "cell-substrate junction disassembly", "d": ["The disaggregation of a cell-substrate junction into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0000128", "l": "flocculation", "d": ["The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019588", "l": "anaerobic glycerol catabolic process", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol, yielding energy in the form of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904025", "l": "positive regulation of glucose catabolic process to lactate via pyruvate", "d": ["Any process that activates or increases the frequency, rate or extent of glucose catabolic process to lactate via pyruvate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0031645", "l": "negative regulation of nervous system process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019356", "l": "nicotinate nucleotide biosynthetic process from tryptophan", "d": ["The chemical reactions and pathways resulting in the formation of nicotinate nucleotide from other compounds, including tryptophan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048452", "l": "petal structural organization", "d": ["The process that contributes to the act of creating the structural organization of the petal. This process pertains to the physical shaping of a rudimentary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.576969997299727", "identifiers": [{"i": "GO:0035929", "l": "steroid hormone secretion", "d": ["The regulated release of any steroid that acts as a hormone into the circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045584", "l": "negative regulation of cytotoxic T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cytotoxic T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900742", "l": "negative regulation of filamentous growth of a population of unicellular organisms in response to pH", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901580", "l": "regulation of telomeric RNA transcription from RNA pol II promoter", "d": ["Any process that modulates the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002269", "l": "leukocyte activation involved in inflammatory response", "d": ["A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000758", "l": "agglutination involved in conjugation with mutual genetic exchange", "d": ["The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation without cellular fusion of a unicellular organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901055", "l": "trimethylenediamine metabolic process", "d": ["The chemical reactions and pathways involving trimethylenediamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0099075", "l": "mitochondrion-derived vesicle mediated transport", "d": ["Transport from the mitochondrion, mediated by mitochondrion derived vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046161", "l": "heme a catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of heme a, a derivative of heme found in cytochrome aa3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009710", "l": "tropane alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110164", "l": "positive regulation of mitotic spindle elongation (spindle phase three)", "d": ["Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060510", "l": "type II pneumocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0000820", "l": "regulation of glutamine family amino acid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014838", "l": "myoblast fate specification involved in skeletal muscle regeneration", "d": ["The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099083", "l": "retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission", "d": ["Modulation of synaptic transmittion by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.679817763985781", "identifiers": [{"i": "GO:0016477", "l": "cell migration", "d": ["The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001010", "l": "negative regulation of plant-type cell wall cellulose biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:1905897", "l": "regulation of response to endoplasmic reticulum stress", "d": ["Any process that modulates the frequency, rate or extent of response to endoplasmic reticulum stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0002028", "l": "regulation of sodium ion transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070494", "l": "regulation of thrombin-activated receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of a thrombin-activated receptor signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032875", "l": "regulation of DNA endoreduplication", "d": ["Any process that modulates the frequency, rate or extent of DNA endoreduplication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0051275", "l": "beta-glucan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of beta-glucans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045201", "l": "maintenance of neuroblast polarity", "d": ["The maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0051899", "l": "membrane depolarization", "d": ["The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034239", "l": "regulation of macrophage fusion", "d": ["Any process that modulates the frequency, rate or extent of macrophage fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904170", "l": "regulation of bleb assembly", "d": ["Any process that modulates the frequency, rate or extent of bleb assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900728", "l": "cardiac neural crest cell delamination involved in outflow tract morphogenesis", "d": ["Any cardiac neural crest cell delamination that is involved in outflow tract morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0051785", "l": "positive regulation of nuclear division", "d": ["Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106154", "l": "perithecium formation", "d": ["The process of producing flask-shaped fruiting bodies, called perithecia. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901518", "l": "aspyridone A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aspyridone A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0022001", "l": "negative regulation of anterior neural cell fate commitment of the neural plate", "d": ["Any process that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0009200", "l": "deoxyribonucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.685364931984026", "identifiers": [{"i": "GO:0017148", "l": "negative regulation of translation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042371", "l": "vitamin K biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072762", "l": "cellular response to carbendazim", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:1903429", "l": "regulation of cell maturation", "d": ["Any process that modulates the frequency, rate or extent of cell maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042152", "l": "RNA-mediated DNA recombination", "d": ["The reverse transcription of an RNA molecule followed by recombination between the resultant cDNA and its homologous chromosomal allele."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032709", "l": "negative regulation of interleukin-25 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-25 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900710", "l": "regulation of tensidol B biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of tensidol B biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0007439", "l": "ectodermal digestive tract development", "d": ["The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045329", "l": "carnitine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060633", "l": "negative regulation of transcription initiation by RNA polymerase II", "d": ["Any process that decreases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006583", "l": "melanin biosynthetic process from tyrosine", "d": ["The chemical reactions and pathways resulting in the formation of melanin from other compounds, including tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0180011", "l": "cytoplasmic polyadenylation", "d": ["Any process by which dormant, translationally inactive mRNAs become activated via the elongation of their poly(A) tails in the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046694", "l": "sperm incapacitation", "d": ["The process in which the use of stored sperm from the first-mating male is inhibited by the seminal fluid of subsequently mating males."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0043030", "l": "regulation of macrophage activation", "d": ["Any process that modulates the frequency or rate of macrophage activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0032410", "l": "negative regulation of transporter activity", "d": ["Any process that stops or reduces the activity of a transporter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0062089", "l": "regulation of taurine biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of taurine biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019533", "l": "cellobiose transport", "d": ["The directed movement of cellobiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0075114", "l": "disruption of host transmembrane receptor-mediated signal transduction", "d": ["Any process in which a symbiont interferes with transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009567", "l": "double fertilization forming a zygote and endosperm", "d": ["Fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033249", "l": "positive regulation of penicillin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106096", "l": "response to ceramide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019696", "l": "toluene oxidation via toluene-cis-1,2-dihydrodiol", "d": ["The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form toluene-cis-1,2-dihydrodiol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0036363", "l": "transforming growth factor beta activation", "d": ["The release of transforming growth factor beta (TGF-beta) from its latent state. TGF-beta is secreted as part of a large latent complex (LLC) that is targeted to the extracellular matrix. Release of TGFbeta from its latent state is required for TGFbeta to bind to its receptors, and can occur by a variety of mechanisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070223", "l": "sulfide oxidation, using sulfur dioxygenase", "d": ["A sulfide oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051417", "l": "microtubule nucleation by spindle pole body", "d": ["The 'de novo' formation of a microtubule, mediated by the spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046891", "l": "peptidyl-cysteine S-carbamoylation", "d": ["The carbamoylation of peptidyl-cysteine to form peptidyl-S-carbamoyl-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033671", "l": "negative regulation of NAD+ kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045587", "l": "negative regulation of gamma-delta T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097195", "l": "pilomotor reflex", "d": ["The reflex process in which the arrectores pilorum (hair follicle) muscles contract and cause the hair to stand erect."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048773", "l": "erythrophore differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an erythrophore cell. Erythrophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives them an orange to red appearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090230", "l": "regulation of centromere complex assembly", "d": ["Any process that modulates the rate, frequency, or extent of centromere complex assembly, the aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032679", "l": "regulation of TRAIL production", "d": ["Any process that modulates the frequency, rate, or extent of TRAIL production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.824318789188837", "identifiers": [{"i": "GO:0009698", "l": "phenylpropanoid metabolic process", "d": ["The chemical reactions and pathways involving aromatic derivatives of trans-cinnamic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0014887", "l": "cardiac muscle adaptation", "d": ["The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:1905214", "l": "regulation of RNA binding", "d": ["Any process that modulates the frequency, rate or extent of RNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0022013", "l": "pallium cell proliferation in forebrain", "d": ["The multiplication or reproduction of pallium cells in the forebrain, resulting in the expansion of the cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007429", "l": "secondary branching, open tracheal system", "d": ["Sprouting of secondary branches in an open tracheal system. These form from the tips of primary branches and are formed by individual cells that roll up into unicellular tubes. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090350", "l": "negative regulation of cellular organofluorine metabolic process", "d": ["Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002266", "l": "follicular dendritic cell activation", "d": ["A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0046543", "l": "development of secondary female sexual characteristics", "d": ["The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. In female humans, these include growth of axillary and pubic hair, breast development and menstrual periods. Their development occurs in response to sex hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080160", "l": "selenate transport", "d": ["The directed movement of selenate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033278", "l": "cell proliferation in midbrain", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.871876592857262", "identifiers": [{"i": "GO:0051261", "l": "protein depolymerization", "d": ["The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019408", "l": "dolichol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043272", "l": "ethylene biosynthesis involved in jasmonic acid and ethylene-dependent systemic resistance", "d": ["The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), occurring as part of the process of jasmonic acid and ethylene-dependent systemic resistance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072008", "l": "glomerular mesangial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the kidney as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060242", "l": "contact inhibition", "d": ["The series of events in which information about the density of cells in a population is received by direct cell-cell contact and is converted into a molecular signal, resulting in the cessation of cell growth or proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042547", "l": "cell wall modification involved in multidimensional cell growth", "d": ["The series of events resulting in chemical or structural changes to existing cell walls and contribute to multidimensional cell growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.155424086811493", "identifiers": [{"i": "GO:0046148", "l": "pigment biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901927", "l": "cadinene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cadinene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0021846", "l": "cell proliferation in forebrain", "d": ["The creation of greater cell numbers in the forebrain due to cell division of progenitor cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060299", "l": "negative regulation of sarcomere organization", "d": ["Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0018058", "l": "N-terminal protein amino acid deamination, from amino carbon", "d": ["The oxidative deamination of the alpha carbon of an encoded N-terminal amino acid, to form pyruvic acid retaining an amide bond between its 1-carboxyl group and the adjacent residue. The pyruvate 2-oxo group may become an enzyme active site, or it may be reduced to an alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0009965", "l": "leaf morphogenesis", "d": ["The process in which the anatomical structures of the leaf are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071309", "l": "cellular response to phylloquinone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009212", "l": "pyrimidine deoxyribonucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060725", "l": "regulation of coreceptor activity", "d": ["Any process that modulates the rate or frequency of coreceptor activity, combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0098762", "l": "meiotic cell cycle phase", "d": ["One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071296", "l": "cellular response to biotin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046426", "l": "negative regulation of receptor signaling pathway via JAK-STAT", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a receptor signaling pathway via JAK-STAT."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000537", "l": "regulation of B cell chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of B cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033609", "l": "oxalate metabolic process", "d": ["The chemical reactions and pathways involving oxalate, the organic acid ethanedioate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002941", "l": "synoviocyte proliferation", "d": ["The multiplication or reproduction of type B synoviocytes by cell division, resulting in the expansion of their population. A type B synoviocyte is a fibroblast-like cell found in synovial tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905947", "l": "positive regulation of response to calcium ion", "d": ["Any process that activates or increases the frequency, rate or extent of response to calcium ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099045", "l": "viral extrusion", "d": ["The process whereby a filamentous phage particle is released from a bacterial host cell via a concerted mechanism of assembly and secretion. Neosynthesized virions are coordinately exported as they are assembled at the cell surface in a secretory process that leaves the host cell fully viable. Non-capsid proteins form structures that facilitate translocation through the inner membrane and outer membranes. A viral single-stranded DNA binding protein coats progeny viral DNA molecules to generate the intracellular precursor for assembly of phage particles as they are extruded through the membranes of the bacterial host. The structural proteins of the virus are anchored in the inner membrane before their incorporation into the phage particle. As assembly proceeds, the phage genome traverses the inner and outer membranes until the entire DNA molecule has been coated and extruded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0044793", "l": "negative regulation by host of viral process", "d": ["A process in which a host organism stops, prevents or reduces the frequency, rate or extent of a process being mediated by a virus with which it is infected."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010819", "l": "regulation of T cell chemotaxis", "d": ["Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0034340", "l": "response to type I interferon", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033621", "l": "nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts", "d": ["The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0080140", "l": "regulation of jasmonic acid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving jasmonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904563", "l": "phosphatidylinositol 5-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidylinositol 5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045696", "l": "positive regulation of embryo sac egg cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of embryo sac egg cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0009225", "l": "nucleotide-sugar metabolic process", "d": ["The cellular chemical reactions and pathways involving nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903086", "l": "negative regulation of sinapate ester biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sinapate ester biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071910", "l": "determination of liver left/right asymmetry", "d": ["Determination of the asymmetric location of the liver with respect to the left and right halves of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015733", "l": "shikimate transmembrane transport", "d": ["The process in which shikimate is transported across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033051", "l": "aminophosphonate metabolic process", "d": ["The chemical reactions and pathways involving aminophosphonates, phosphonic acid derivatives that contain an amino group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036512", "l": "trimming of second mannose on A branch", "d": ["The removal of the second alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052074", "l": "positive regulation by symbiont of host salicylic acid-mediated defense response", "d": ["Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905109", "l": "regulation of pulmonary blood vessel remodeling", "d": ["Any process that modulates the frequency, rate or extent of pulmonary blood vessel remodeling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070831", "l": "basement membrane assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015976", "l": "carbon utilization", "d": ["A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing substances, and ends when carbon is incorporated into the cell or organism's metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006964", "l": "positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria", "d": ["Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0060972", "l": "left/right pattern formation", "d": ["The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901451", "l": "regulation of response to benzene", "d": ["Any process that modulates the frequency, rate or extent of response to benzene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900432", "l": "negative regulation of filamentous growth of a population of unicellular organisms in response to heat", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003113", "l": "positive regulation of heart rate by neuronal norepinephrine", "d": ["The process in which the secretion of norepinephrine released from nerve endings increases the rate of heart muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014871", "l": "cross bridge formation involved in regulation of the velocity of shortening in skeletal muscle contraction", "d": ["The process in which actin and myosin interact, split ATP and generate force during skeletal muscle contraction. This process is one of the components of the regulation of the force of skeletal muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901836", "l": "regulation of transcription of nucleolar large rRNA by RNA polymerase I", "d": ["Any process that modulates the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0071559", "l": "response to transforming growth factor beta", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045689", "l": "negative regulation of antipodal cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of antipodal cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032225", "l": "regulation of synaptic transmission, dopaminergic", "d": ["Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061096", "l": "negative regulation of turning behavior involved in mating", "d": ["Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090462", "l": "intracellular ornithine homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of orthinine within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000469", "l": "negative regulation of peroxidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of peroxidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902207", "l": "positive regulation of interleukin-2-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-2-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902567", "l": "negative regulation of eosinophil activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:2000758", "l": "positive regulation of peptidyl-lysine acetylation", "d": ["Any process that activates or increases the frequency, rate or extent of peptidyl-lysine acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044467", "l": "glial cell-derived neurotrophic factor production", "d": ["The regulated release of glial cell line-derived neurotrophic factor from a cell. Glial cell-derived neurotrophic factor (GDNF) is a small protein that potently promotes the survival of many types of neurons, notably dopaminergic and motor neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905091", "l": "positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization", "d": ["Any process that activates or increases the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120303", "l": "visually-mediated background adaptation", "d": ["Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by melanopsin-expressing eye cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904032", "l": "regulation of t-SNARE clustering", "d": ["Any process that modulates the frequency, rate or extent of t-SNARE clustering."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0006414", "l": "translational elongation", "d": ["The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018288", "l": "iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071923", "l": "negative regulation of cohesin loading", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072032", "l": "proximal convoluted tubule segment 2 development", "d": ["The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901268", "l": "cephalosporin C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cephalosporin C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035464", "l": "regulation of transforming growth factor receptor beta signaling pathway involved in determination of left/right asymmetry", "d": ["Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway that is involved in the determination of organismal asymmetry with regard to its left and right halves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000673", "l": "positive regulation of motor neuron apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0097201", "l": "negative regulation of transcription from RNA polymerase II promoter in response to stress", "d": ["Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034403", "l": "alignment of 3' and 5' splice sites of mRNA", "d": ["Recognition of both the 5' and 3'-splice sites and positioning them in the correct alignment with respect to each other so that the second catalytic step of nuclear mRNA splicing can occur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034243", "l": "regulation of transcription elongation by RNA polymerase II", "d": ["Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003237", "l": "sinus venosus formation", "d": ["The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010985", "l": "negative regulation of lipoprotein particle clearance", "d": ["Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0052009", "l": "disruption by symbiont of host cell wall", "d": ["A process carried out by a symbiont that breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900821", "l": "orlandin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of orlandin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070676", "l": "intralumenal vesicle formation", "d": ["The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008103", "l": "oocyte microtubule cytoskeleton polarization", "d": ["Establishment and maintenance of a specific axis of polarity of the oocyte microtubule network. The axis is set so that the minus and plus ends of the microtubules of the mid stage oocyte are positioned along the anterior cortex and at the posterior pole, respectively. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035884", "l": "arabinan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of arabinan, a polysaccharide composed of arabinose residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902255", "l": "positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "d": ["Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:2000114", "l": "regulation of establishment of cell polarity", "d": ["Any process that modulates the frequency, rate or extent of establishment of cell polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052164", "l": "symbiont defense to host-produced reactive oxygen species", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003400", "l": "regulation of COPII vesicle coating", "d": ["Any process that modulates the rate, frequency, or extent of the addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010778", "l": "meiotic DNA repair synthesis involved in reciprocal meiotic recombination", "d": ["The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0002062", "l": "chondrocyte differentiation", "d": ["The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009563", "l": "synergid differentiation", "d": ["The process in which an uncellularized nucleus cellularizes and acquires the specialized features of a synergid cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042000", "l": "translocation of peptides or proteins into host", "d": ["The directed movement of peptides or proteins produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046462", "l": "monoacylglycerol metabolic process", "d": ["The chemical reactions and pathways involving monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0140590", "l": "effector-mediated suppression of host defense response", "d": ["A process mediated by a molecule secreted by a symbiont that results in the supression of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.98780181426379", "identifiers": [{"i": "GO:0031268", "l": "pseudopodium organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903770", "l": "negative regulation of beta-galactosidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of beta-galactosidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046355", "l": "mannan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000372", "l": "Group I intron splicing", "d": ["The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097331", "l": "response to cytarabine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytarabine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019393", "l": "glucarate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucarate, the anion of glucaric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010394", "l": "homogalacturonan metabolic process", "d": ["The chemical reactions and pathways involving homogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0034614", "l": "cellular response to reactive oxygen species", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000672", "l": "negative regulation of motor neuron apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160073", "l": "Casparian strip assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a Casparian strip, a region of plant cell wall specialised to act as a seal to prevent back leakage of secreted material."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001213", "l": "negative regulation of vasculogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015795", "l": "sorbitol transmembrane transport", "d": ["The directed movement of sorbitol across a membrane. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090519", "l": "anoxia protection", "d": ["Any process in which an organism or cell protects itself from anoxia, which may also result in resistance to repeated exposure to anoxia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.905555711669919", "identifiers": [{"i": "GO:0030537", "l": "larval behavior", "d": ["Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035777", "l": "pronephric distal tubule development", "d": ["The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046713", "l": "borate transport", "d": ["The directed movement of borate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903891", "l": "regulation of ATF6-mediated unfolded protein response", "d": ["Any process that modulates the frequency, rate or extent of the ATF6-mediated unfolded protein response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "47.94201155806968", "identifiers": [{"i": "GO:0098916", "l": "anterograde trans-synaptic signaling", "d": ["Cell-cell signaling from pre to post-synapse, across the synaptic cleft."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070843", "l": "misfolded protein transport", "d": ["The directed movement of misfolded proteins in a cell, including the movement of proteins between specific compartments or structures within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:0043903", "l": "regulation of biological process involved in symbiotic interaction", "d": ["Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1903792", "l": "negative regulation of monoatomic anion transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anion transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071315", "l": "cellular response to morphine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "37.015827766557585", "identifiers": [{"i": "GO:0002009", "l": "morphogenesis of an epithelium", "d": ["The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051165", "l": "2,5-dihydroxypyridine metabolic process", "d": ["The chemical reactions and pathways involving 2,5-dihydroxypyridine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0018197", "l": "peptidyl-aspartic acid modification", "d": ["The modification of peptidyl-aspartic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0044088", "l": "regulation of vacuole organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003219", "l": "cardiac right ventricle formation", "d": ["The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010267", "l": "ta-siRNA processing", "d": ["A process leading to the generation of a functional trans-acting small interfering RNA (ta-siRNA). ta-siRNAs function like miRNAs to guide cleavage of target mRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018109", "l": "peptidyl-arginine phosphorylation", "d": ["The phosphorylation of peptidyl-arginine to form omega-N-phospho-L-arginine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042208", "l": "propylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070930", "l": "trans-translation-dependent protein tagging", "d": ["A protein modification process in which a polypeptide is added to a nascent polypeptide cotranslationally by trans-translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0045010", "l": "actin nucleation", "d": ["The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043406", "l": "positive regulation of MAP kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of MAP kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034438", "l": "lipoprotein amino acid oxidation", "d": ["The modification of a lipoprotein by oxidation of one or more amino acids in the protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048094", "l": "male pigmentation", "d": ["Establishment of a pattern of pigment in males."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075342", "l": "disruption by symbiont of host cell PML body", "d": ["The breakdown, by the symbiont, of a PML body within a host cell. A PML body is a nuclear body that reacts against SP100 auto-antibodies (PML = promyelocytic leukemia). The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003193", "l": "pulmonary valve formation", "d": ["The developmental process pertaining to the initial formation of the pulmonary valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034149", "l": "positive regulation of toll-like receptor 5 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 5 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905914", "l": "positive regulation of calcium ion export across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion export across the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160048", "l": "craniofacial suture closure", "d": ["The process of fusing together the edges of a craniofacial suture."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002676", "l": "regulation of chronic inflammatory response", "d": ["Any process that modulates the frequency, rate, or extent of a chronic inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045328", "l": "cytochrome P450 4A1-heme linkage", "d": ["The covalent linkage of heme to cytochrome P450 4A1 via hydroxyheme-L-glutamyl ester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031652", "l": "positive regulation of heat generation", "d": ["Any process that activates or increases the rate or extent of heat generation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.527781272052167", "identifiers": [{"i": "GO:0061448", "l": "connective tissue development", "d": ["The progression of a connective tissue over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044579", "l": "butyryl-CoA biosynthetic process from acetyl-CoA", "d": ["The chemical reactions and pathway resulting in the formation of butyryl-CoA, starting from acetyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0039537", "l": "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the host viral-induced cytoplasmic pattern recognition receptor signaling pathway. This is a mechanism by which the virus evades the host innate immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1903052", "l": "positive regulation of proteolysis involved in protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of proteolysis involved in protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060749", "l": "mammary gland alveolus development", "d": ["The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002212", "l": "behavioral defense response to nematode", "d": ["A behavioral response seeking to protect an organism from an a perceived external threat from a nematode or nematodes to that organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019360", "l": "nicotinamide nucleotide biosynthetic process from niacinamide", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide nucleotide from other compounds, including niacinamide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140724", "l": "positive regulation of patulin biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of patulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010304", "l": "PSII associated light-harvesting complex II catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0036181", "l": "protein localization to linear element", "d": ["A cellular protein localization process in which a protein is transported to, or maintained at, a linear element. A linear element is a proteinaceous scaffold associated with S. pombe chromosomes during meiotic prophase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046626", "l": "regulation of insulin receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of insulin receptor signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045774", "l": "negative regulation of beta 2 integrin biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009949", "l": "polarity specification of anterior/posterior axis", "d": ["Any process resulting in the establishment of polarity along the anterior/posterior axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1905161", "l": "protein localization to phagocytic vesicle", "d": ["A process in which a protein is transported to, or maintained in, a location within a phagocytic vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007096", "l": "regulation of exit from mitosis", "d": ["Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018259", "l": "RNA-protein covalent cross-linking via peptidyl-serine", "d": ["The formation of a covalent cross-link between RNA and a peptidyl-serine residue by the formation of O-(phospho-5'-5NA)-L-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902318", "l": "synthesis of RNA primer involved in nuclear cell cycle DNA replication", "d": ["Any synthesis of RNA primer that is involved in nuclear cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0044002", "l": "acquisition of nutrients from host", "d": ["The process that begins with the production and formation of structures and molecules in an organism that are required for the acquisition and utilization of nutrients from its host organism, and the ends with the acquirement of the nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900342", "l": "regulation of methane biosynthetic process from dimethyl sulfide", "d": ["Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904086", "l": "regulation of epiboly involved in gastrulation with mouth forming second", "d": ["Any process that modulates the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042544", "l": "melibiose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.158834410454425", "identifiers": [{"i": "GO:0048284", "l": "organelle fusion", "d": ["The creation of a single organelle from two or more organelles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043095", "l": "regulation of GTP cyclohydrolase I activity", "d": ["Any process that modulates the activity of the enzyme GTP cyclohydrolase I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045966", "l": "positive regulation of ecdysteroid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0042869", "l": "aldarate transmembrane transport", "d": ["The process in which aldarate is transported across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1905405", "l": "regulation of mitotic cohesin loading", "d": ["Any process that modulates the frequency, rate or extent of mitotic cohesin loading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.586422797268227", "identifiers": [{"i": "GO:0032060", "l": "bleb assembly", "d": ["The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0075025", "l": "initiation of appressorium formation", "d": ["The process in which a relatively unspecialized cell starts to acquire specialized features of the symbiont appressorium to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061359", "l": "regulation of Wnt signaling pathway by Wnt protein secretion", "d": ["Any process that modulates the frequency, rate or extent of the activity of the Wnt signaling pathway by the controlled release of a Wnt protein from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071690", "l": "cardiac muscle myosin thick filament assembly", "d": ["The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in cardiac muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000555", "l": "negative regulation of T-helper 1 cell cytokine production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018069", "l": "peptide cross-linking via 4'-(L-tryptophan)-L-tryptophyl quinone", "d": ["The cross-linking of a tryptophan residue to tryptophyl quinone to form 4'-(L-tryptophan)-L-tryptophyl quinone, a cofactor found at the active site of methylamine dehydrogenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900291", "l": "regulation of galactotriose transport", "d": ["Any process that modulates the frequency, rate or extent of galactotriose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006617", "l": "SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition", "d": ["The process in which SRP binds to the signal peptide in a nascent protein, causing protein elongation to pause, during cotranslational membrane targeting."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015806", "l": "S-methylmethionine transport", "d": ["The directed movement of S-methylmethionine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090507", "l": "phenylethylamine metabolic process involved in synaptic transmission", "d": ["The chemical reactions and pathways involving phenylethylamine that contribute to synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903526", "l": "negative regulation of membrane tubulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane tubulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046373", "l": "L-arabinose metabolic process", "d": ["The chemical reactions and pathways involving L-arabinose, the D-enantiomer of arabino-pentose. L-arabinose occurs free, e.g. in the heartwood of many conifers, and in the combined state, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides etc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.905555711669919", "identifiers": [{"i": "GO:1903008", "l": "organelle disassembly", "d": ["The disaggregation of an organelle into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904806", "l": "regulation of protein oxidation", "d": ["Any process that modulates the frequency, rate or extent of protein oxidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035025", "l": "positive regulation of Rho protein signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0015701", "l": "bicarbonate transport", "d": ["The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043420", "l": "anthranilate metabolic process", "d": ["The chemical reactions and pathways involving anthranilate (2-aminobenzoate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060505", "l": "epithelial cell proliferation involved in lung bud dilation", "d": ["The multiplication or reproduction of epithelial cells that contribute to the radial growth of a lung bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000952", "l": "aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanoate, 4-hydroxyphenylethanoate, or 2-(Indol-3-yl)-ethanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0014057", "l": "positive regulation of acetylcholine secretion, neurotransmission", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034203", "l": "glycolipid translocation", "d": ["The translocation, or flipping, of glycolipid molecules from one monolayer of a membrane bilayer to the opposite monolayer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0071462", "l": "cellular response to water stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0034300", "l": "sporangiospore formation", "d": ["The process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001089", "l": "maltotriose transport", "d": ["The directed movement of a maltotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099044", "l": "vesicle tethering to endoplasmic reticulum", "d": ["The initial, indirect interaction between a transport vesicle membrane and the membrane of the endoplasmic reticulum. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046327", "l": "glycerol biosynthetic process from pyruvate", "d": ["The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, from other compounds, including pyruvate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001016", "l": "positive regulation of skeletal muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902958", "l": "positive regulation of mitochondrial electron transport, NADH to ubiquinone", "d": ["Any process that activates or increases the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032065", "l": "maintenance of protein location in cell cortex", "d": ["A process in which a protein or protein complex is maintained in a specific location in the cell cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106336", "l": "yolk syncytial layer development", "d": ["The progression of the yolk syncytial layer over time, from its initial formation to the mature structure. The yolk syncytial layer is the peripheral layer of the yolk cell including nuclei and non-yolky cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060121", "l": "vestibular receptor cell stereocilium organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of vestibular hair cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080185", "l": "effector-mediated induction of plant hypersensitive response by symbiont", "d": ["A symbiont process in which a molecule secreted by the symbiont activates a resistance gene-dependent defense response signaling pathway in the plant host, in order to activate a hypersensitive response to induce necrosis. In the plant, this process involves the direct or indirect recognition of the symbiont effector protein for example through plant resistance receptor or R proteins (or R genes)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070994", "l": "detection of oxidative stress", "d": ["The series of events in which a stimulus indicating oxidative stress is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009772", "l": "photosynthetic electron transport in photosystem II", "d": ["A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, Q) through a chain of electron transport molecules in the thylakoid membrane until they reach the ultimate electron acceptor of Photosystem II, which is plastocyanin (PC). The electron is then passed to the P700 chlorophyll a molecules of the reaction centre of photosystem I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.180456990045087", "identifiers": [{"i": "GO:0015850", "l": "organic hydroxy compound transport", "d": ["The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001192", "l": "negative regulation of gamma-delta T cell activation involved in immune response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gamma-delta T cell activation involved in immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048778", "l": "regulation of erythrophore differentiation", "d": ["Any process that modulates the frequency, rate or extent of erythrophore differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0006418", "l": "tRNA aminoacylation for protein translation", "d": ["The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061280", "l": "epithelial cell migration involved in mesonephric proximal tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003115", "l": "regulation of vasoconstriction by epinephrine", "d": ["Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream or released by nerve endings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902884", "l": "positive regulation of response to oxidative stress", "d": ["Any process that activates or increases the frequency, rate or extent of response to oxidative stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900617", "l": "emericellamide A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of emericellamide A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000977", "l": "regulation of forebrain neuron differentiation", "d": ["Any process that modulates the frequency, rate or extent of forebrain neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0035822", "l": "gene conversion", "d": ["A DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor. The resulting acceptor sequence is identical to that of the donor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019428", "l": "allantoin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of allantoin, (2,5-dioxo-4-imidazolidinyl)urea."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033466", "l": "trans-zeatin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072360", "l": "vascular cord development", "d": ["The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0090317", "l": "negative regulation of intracellular protein transport", "d": ["Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0003208", "l": "cardiac ventricle morphogenesis", "d": ["The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061375", "l": "mammillotectal axonal tract development", "d": ["The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030476", "l": "ascospore wall assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an ascospore wall. During sporulation in Ascomycota, each ascospore nucleus becomes surrounded by a specialized spore wall, formed by deposition of spore wall components in the lumenal space between the outer and inner leaflets of the prospore membrane. An example of this process is found in Saccharomyces cerevisiae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010250", "l": "S-methylmethionine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of S-methyl-methionine (SMM) from methionine and S-adenosyl-methionine (Ado-Met), catalyzed by methionine S-methyltransferase (MMT). SMM can be reconverted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000572", "l": "positive regulation of interleukin-4-dependent isotype switching to IgE isotypes", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1905343", "l": "regulation of cohesin unloading", "d": ["Any process that modulates the frequency, rate or extent of cohesin unloading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.920089577627991", "identifiers": [{"i": "GO:0097237", "l": "cellular response to toxic substance", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903587", "l": "regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "d": ["Any process that modulates the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033481", "l": "galacturonate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of galacturonate, the anion of galacturonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905023", "l": "positive regulation of threonine-tRNA ligase activity", "d": ["Any process that activates or increases the frequency, rate or extent of threonine-tRNA ligase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903572", "l": "positive regulation of protein kinase D signaling", "d": ["Any process that activates or increases the frequency, rate or extent of protein kinase D signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048281", "l": "inflorescence morphogenesis", "d": ["The process in which the anatomical structures of inflorescences are generated and organized. An inflorescence is the part of a seed plant body that is usually above ground and that can bear flowers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0019805", "l": "quinolinate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032364", "l": "intracellular oxygen homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of oxygen within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0099558", "l": "maintenance of synapse structure", "d": ["A process that preserves the structural organistation and orientation of a synaptic cellular component such as the synaptic cytoskeleton and molecular scaffolds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905020", "l": "positive regulation of methionine-tRNA ligase activity", "d": ["Any process that activates or increases the frequency, rate or extent of methionine-tRNA ligase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900651", "l": "positive regulation of dehydroaustinol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of dehydroaustinol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009610", "l": "response to symbiotic fungus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0050819", "l": "negative regulation of coagulation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901333", "l": "positive regulation of lateral root development", "d": ["Any process that activates or increases the frequency, rate or extent of lateral root development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072279", "l": "convergent extension involved in metanephric nephron morphogenesis", "d": ["The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.809526531696484", "identifiers": [{"i": "GO:0048732", "l": "gland development", "d": ["The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0043555", "l": "regulation of translation in response to stress", "d": ["Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043048", "l": "dolichyl monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a phosphorylated dolichol derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.957130793257818", "identifiers": [{"i": "GO:1901575", "l": "organic substance catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0035120", "l": "post-embryonic appendage morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of an appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010198", "l": "synergid death", "d": ["Synergid cells undergo degeneration and death in response to penetration by the pollen tube. It is an active process that involves a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001081", "l": "nitrogen catabolite repression of transcription from RNA polymerase II promoter", "d": ["A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061875", "l": "negative regulation of hepatic stellate cell contraction", "d": ["Any process that modulates stops, prevents, or reduces the frequency, rate or extent of hepatic stellate cell contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061219", "l": "mesonephric mesenchyme development", "d": ["The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1901608", "l": "regulation of vesicle transport along microtubule", "d": ["Any process that modulates the frequency, rate or extent of vesicle transport along microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000256", "l": "allantoin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009452", "l": "7-methylguanosine RNA capping", "d": ["The sequence of enzymatic reactions by which the 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904015", "l": "cellular response to serotonin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001144", "l": "regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0030730", "l": "sequestering of triglyceride", "d": ["The process of binding or confining any triester of glycerol such that it is separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044638", "l": "envenomation resulting in positive regulation of complement activation, classical pathway in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the positive regulation of complement activation via the classical pathway of the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905660", "l": "mitotic checkpoint complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a mitotic checkpoint complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046191", "l": "aerobic phenol-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0048679", "l": "regulation of axon regeneration", "d": ["Any process that modulates the frequency, rate or extent of axon regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090737", "l": "telomere maintenance via telomere trimming", "d": ["A process that contributes to the maintenance of proper telomeric length and structure via the activation of telomere shortening pathways that compensate telomerase-dependent excessive telomere elongation. Telomere attrition is mediated by a mechanism which involves the generation of single-stranded C-rich telomeric DNA, and the formation and removal of double-stranded telomeric circular DNA (T-circles). Telomere trimming is an independent pathway to recombination-mediated telomere elongation and the well-documented gradual telomere attrition that accompanies cellular replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901270", "l": "lipooligosaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lipooligosaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060335", "l": "positive regulation of type II interferon-mediated signaling pathway", "d": ["Any process that increases the rate, frequency or extent of an interferon-gamma-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0046440", "l": "L-lysine metabolic process", "d": ["The chemical reactions and pathways involving L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid, i.e. (2S)-2,6-diaminohexanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106278", "l": "regulation of UDP-N-acetylglucosamine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the UDP-N_acetylglucosamine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022614", "l": "membrane to membrane docking", "d": ["The initial attachment of a membrane to a target membrane, mediated by proteins protruding from the two membranes. Docking requires only that the membranes come close enough for the proteins to interact and adhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040015", "l": "negative regulation of multicellular organism growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903668", "l": "negative regulation of chemorepellent activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chemorepellent activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902813", "l": "negative regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.330199557084356", "identifiers": [{"i": "GO:2000027", "l": "regulation of animal organ morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of animal organ morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019512", "l": "lactose catabolic process via tagatose-6-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate tagatose-6-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903588", "l": "negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010061", "l": "regulation of trichoblast fate specification", "d": ["Any process that modulates trichoblast fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990443", "l": "peptidyl-threonine autophosphorylation", "d": ["The phosphorylation by a protein of one or more of its own threonine amino acid residues, or a threonine residue on an identical protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021571", "l": "rhombomere 5 development", "d": ["The process whose specific outcome is the progression of rhombomere 5 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0050772", "l": "positive regulation of axonogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of axonogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0031134", "l": "sister chromatid biorientation", "d": ["The cell cycle process in which sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0003283", "l": "atrial septum development", "d": ["The progression of the atrial septum over time, from its initial formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098987", "l": "regulation of modification of synapse structure, modulating synaptic transmission", "d": ["Any process that regulates the modification of synaptic structure and as a result regulates synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0097588", "l": "archaeal or bacterial-type flagellum-dependent cell motility", "d": ["Cell motility due to movement of bacterial- or archaeal-type flagella."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034975", "l": "protein folding in endoplasmic reticulum", "d": ["A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072744", "l": "cellular response to trichodermin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0032310", "l": "prostaglandin secretion", "d": ["The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072185", "l": "metanephric cap development", "d": ["The biological process whose specific outcome is the progression of the metanephric cap from an initial condition to its mature state. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001128", "l": "methane biosynthetic process from methylamine", "d": ["The chemical reactions and pathways resulting in the formation of a methane from a methylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000444", "l": "negative regulation of toll-like receptor 21 signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 21 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904342", "l": "negative regulation of colon smooth muscle contraction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1901562", "l": "response to paraquat", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046312", "l": "phosphoarginine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphoarginine, a phosphorylated derivative of the amino acid arginine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002136", "l": "tRNA wobble base lysidine biosynthesis", "d": ["The process in which the carbonyl of cytosine at position 34 of a tRNA is post-transcriptionally replaced by lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.086235947127733", "identifiers": [{"i": "GO:1901293", "l": "nucleoside phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nucleoside phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.824318789188837", "identifiers": [{"i": "GO:0046835", "l": "carbohydrate phosphorylation", "d": ["The process of introducing a phosphate group into a carbohydrate, any organic compound based on the general formula Cx(H2O)y."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046850", "l": "regulation of bone remodeling", "d": ["Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0002209", "l": "behavioral defense response", "d": ["A behavioral response seeking to protect an organism from an a perceived external threat to that organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060474", "l": "positive regulation of flagellated sperm motility involved in capacitation", "d": ["The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0052026", "l": "modulation by symbiont of host transcription", "d": ["Any process in which an organism modulates the frequency, rate or extent of its host's transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061558", "l": "cranial ganglion maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048911", "l": "efferent axon development in anterior lateral line nerve", "d": ["The process whose specific outcome is the progression of an efferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the anterior lateral line nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019471", "l": "4-hydroxyproline metabolic process", "d": ["The chemical reactions and pathways involving 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. The presence of hydroxyproline is essential to produce stable triple helical tropocollagen, hence the problems caused by ascorbate deficiency in scurvy. This unusual amino acid is also present in considerable amounts in the major glycoprotein of primary plant cell walls."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905270", "l": "Meynert cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a Meynert cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.664775500092716", "identifiers": [{"i": "GO:0098869", "l": "cellular oxidant detoxification", "d": ["Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010791", "l": "DNA double-strand break processing involved in repair via synthesis-dependent strand annealing", "d": ["The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via synthesis-dependent strand annealing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0015855", "l": "pyrimidine nucleobase transport", "d": ["The directed movement of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001267", "l": "regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060815", "l": "regulation of translation involved in anterior/posterior axis specification", "d": ["Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098849", "l": "cellular detoxification of cadmium ion", "d": ["Any process that reduces or removes the toxicity of cadmium cations in a cell. These include transport of cadmium cations away from sensitive areas and to compartments or complexes whose purpose is sequestration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043635", "l": "methylnaphthalene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of methylnaphthalene, an organic compound, C10H7CH3, obtained from coal tar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.415093686714229", "identifiers": [{"i": "GO:0002920", "l": "regulation of humoral immune response", "d": ["Any process that modulates the frequency, rate, or extent of a humoral immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045220", "l": "positive regulation of FasL production", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0009648", "l": "photoperiodism", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. The critical day length varies between species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030723", "l": "ovarian fusome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of ovarian cells, an organelle derived from the spectrosome. It anchors the mitotic spindle pole to provide orientation during cystoblast cell divisions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.248384282929521", "identifiers": [{"i": "GO:2000242", "l": "negative regulation of reproductive process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070731", "l": "cGMP transport", "d": ["The directed movement of cyclic GMP (cGMP), into, out of or within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070881", "l": "regulation of proline transport", "d": ["Any process that modulates the frequency, rate or extent of proline transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106046", "l": "guanine deglycation, glyoxal removal", "d": ["The removal of glyoxal from a glycated guanine, to form glycolate and a deglycated guanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060301", "l": "positive regulation of cytokine activity", "d": ["Any process that increases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.644186068201407", "identifiers": [{"i": "GO:0048469", "l": "cell maturation", "d": ["The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0022615", "l": "protein to membrane docking", "d": ["The initial attachment of a protein to a target membrane, mediated by a proteins protruding from the target membrane. Docking requires only that the proteins come close enough to interact and adhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072134", "l": "nephrogenic mesenchyme morphogenesis", "d": ["The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000874", "l": "regulation of glyoxylate cycle", "d": ["Any process that modulates the frequency, rate or extent of glyoxylate cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071671", "l": "regulation of smooth muscle cell chemotaxis", "d": ["Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000614", "l": "positive regulation of thyroid-stimulating hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of thyroid-stimulating hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.60886360909339", "identifiers": [{"i": "GO:0015931", "l": "nucleobase-containing compound transport", "d": ["The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0090435", "l": "protein localization to nuclear envelope", "d": ["A process in which a protein is transported to, or maintained at, a location within a nuclear envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0002943", "l": "tRNA dihydrouridine synthesis", "d": ["The process whereby a uridine in a transfer RNA is converted to dihydrouridine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900053", "l": "negative regulation of retinoic acid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of retinoic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019390", "l": "glucuronoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044636", "l": "envenomation resulting in modulation of complement activation, classical pathway in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the regulation of complement activation via the classical pathway of the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905029", "l": "positive regulation of membrane depolarization during AV node cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of membrane depolarization during AV node cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097749", "l": "membrane tubulation", "d": ["A membrane organization process resulting in the formation of a tubular projection. This may face inwardly (as in tubular membrane invaginations) or outwardly (as in endosomal tubules)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:2000099", "l": "regulation of establishment or maintenance of bipolar cell polarity", "d": ["Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:1902750", "l": "negative regulation of cell cycle G2/M phase transition", "d": ["Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110072", "l": "apical constriction involved in ventral furrow formation", "d": ["The actin-mediated process that results in contraction of the apical end of a polarized columnar epithelial cell, contributing to formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903838", "l": "negative regulation of mRNA 3'-UTR binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mRNA 3'-UTR binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.330951936344348", "identifiers": [{"i": "GO:0000041", "l": "transition metal ion transport", "d": ["The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:1900378", "l": "positive regulation of secondary metabolite biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0017000", "l": "antibiotic biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0042255", "l": "ribosome assembly", "d": ["The aggregation, arrangement and bonding together of the mature ribosome and of its subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003324", "l": "pancreatic D cell development", "d": ["The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098972", "l": "anterograde dendritic transport of mitochondrion", "d": ["The directed movement of mitochondria along microtubules in dendrites towards the postsynapse and away from the cell body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901279", "l": "D-ribose 5-phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-ribose 5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902572", "l": "negative regulation of serine-type peptidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of serine-type peptidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.733023282803451", "identifiers": [{"i": "GO:0006954", "l": "inflammatory response", "d": ["The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0062170", "l": "lutein metabolic process", "d": ["The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform lutein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006105", "l": "succinate metabolic process", "d": ["The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0008354", "l": "germ cell migration", "d": ["The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070447", "l": "positive regulation of oligodendrocyte progenitor proliferation", "d": ["Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0048892", "l": "lateral line nerve development", "d": ["The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060769", "l": "positive regulation of epithelial cell proliferation involved in prostate gland development", "d": ["Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072647", "l": "interferon-epsilon production", "d": ["The appearance of interferon-epsilon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052112", "l": "occlusion by symbiont of host xylem", "d": ["The process in which an organism reduces the flow of fluid within the host xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:1902967", "l": "protein localization to mitotic spindle midzone", "d": ["A process in which a protein is transported to, or maintained in, a location within a mitotic spindle midzone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902371", "l": "negative regulation of tRNA catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tRNA catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.760111289607934", "identifiers": [{"i": "GO:0050673", "l": "epithelial cell proliferation", "d": ["The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048662", "l": "negative regulation of smooth muscle cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0042732", "l": "D-xylose metabolic process", "d": ["The chemical reactions and pathways involving D-xylose, a naturally occurring plant polysaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904727", "l": "negative regulation of replicative senescence", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of replicative senescence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0160017", "l": "regulation of platelet rolling", "d": ["Any process that modulates the frequency, rate or extent of platelet rolling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070092", "l": "regulation of glucagon secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of glucagon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901411", "l": "negative regulation of tetrapyrrole biosynthetic process from glutamate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002336", "l": "B-1 B cell lineage commitment", "d": ["The process in which an immature B cell becomes committed to become a B-1 B cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044527", "l": "formation of peptidyl-cystine persulfide by sulphur transfer from H2S", "d": ["The modification of a peptidyl-cystine residue in a protein by the direct addition of H2S, followed by the removal of 2 protons to form peptidyl-cysteine persulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.82875340147023", "identifiers": [{"i": "GO:0050801", "l": "monoatomic ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of monoatomic ions within an organism or cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0097623", "l": "potassium ion export across plasma membrane", "d": ["The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0009414", "l": "response to water deprivation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044634", "l": "negative regulation of complement activation, alternative pathway in another organism", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway, in a different organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060842", "l": "arterial endothelial cell differentiation", "d": ["The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071570", "l": "cement gland development", "d": ["The process whose specific outcome is the progression of the cement gland over time, from its formation to the mature structure. The cement gland is a simple mucus-secreting organ positioned at the anterior of amphibious embryos. The cement gland attaches the newly hatched embryo to a support before the hatchling can swim well or feed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009904", "l": "chloroplast accumulation movement", "d": ["The relocation process in which chloroplasts in photosynthetic cells move toward a brighter area in a cell to optimize photosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:1902100", "l": "negative regulation of metaphase/anaphase transition of cell cycle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046269", "l": "toluene-4-sulfonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of toluene-4-sulfonate, 4-methylbenzenesulfonate, the anion of sulfonic acid attached to a methylbenzene molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904835", "l": "dorsal root ganglion morphogenesis", "d": ["The developmental process by which a dorsal root ganglion is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042928", "l": "ferrichrome import into cell", "d": ["A process in which ferrichrome is transported into the cell by specific cell surface receptors. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021582", "l": "medulla oblongata maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036068", "l": "light-independent chlorophyll biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the absence of light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904663", "l": "regulation of N-terminal peptidyl-methionine acetylation", "d": ["Any process that modulates the frequency, rate or extent of N-terminal peptidyl-methionine acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019475", "l": "L-lysine catabolic process to acetate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035262", "l": "gonad morphogenesis", "d": ["The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901286", "l": "iron-sulfur-molybdenum cofactor metabolic process", "d": ["The chemical reactions and pathways involving iron-sulfur-molybdenum cofactor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044392", "l": "peptidyl-lysine malonylation", "d": ["The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903855", "l": "positive regulation of stress response to copper ion", "d": ["Any process that activates or increases the frequency, rate or extent of stress response to copper ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046901", "l": "tetrahydrofolylpolyglutamate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0034627", "l": "'de novo' NAD biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan or aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900500", "l": "regulation of butyryl-CoA catabolic process to butyrate", "d": ["Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butyrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0099601", "l": "regulation of neurotransmitter receptor activity", "d": ["Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106150", "l": "zearalenone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of zearalenone, a mycotoxin produced by several Fusarium species, is most commonly found as a contaminant in stored grain and has chronic estrogenic effects on mammals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905580", "l": "positive regulation of ERBB3 signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of ERBB3 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140913", "l": "viral release via disruption of host peptidoglycan cell wall", "d": ["The dissemination of mature viral particles from a host cell, caused by a virus hydrolyzing the peptidoglycan cell wall of the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000998", "l": "negative regulation of cellulose catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellulose catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900831", "l": "D-leucine metabolic process", "d": ["The chemical reactions and pathways involving D-leucine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015911", "l": "long-chain fatty acid import across plasma membrane", "d": ["The directed movement of a long-chain fatty acid from outside of a cell, across the plasma membrane and into the cytosol. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034393", "l": "positive regulation of smooth muscle cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033326", "l": "cerebrospinal fluid secretion", "d": ["The regulated release of cerebrospinal fluid (CSF) from the choroid plexus of the lateral, third and fourth ventricles. The cerebrospinal fluid is a clear liquid that located within the ventricles, spinal canal, and subarachnoid spaces."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016318", "l": "ommatidial rotation", "d": ["The process in which photoreceptors are arranged in ommatidia in the dorsal and ventral fields to be mirror images. The polarity is established in the imaginal discs concurrently with cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046710", "l": "GDP metabolic process", "d": ["The chemical reactions and pathways involving GDP, guanosine 5'-diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0006953", "l": "acute-phase response", "d": ["An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090137", "l": "epithelial cell-cell adhesion involved in epithelium migration", "d": ["The attachment of an epithelial cell to another epithelial cell via adhesion molecules that contributes to epithelium migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904705", "l": "regulation of vascular associated smooth muscle cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002068", "l": "glandular epithelial cell development", "d": ["The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0010623", "l": "programmed cell death involved in cell development", "d": ["The activation of endogenous cellular processes that result in the death of a cell as part of its development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0021983", "l": "pituitary gland development", "d": ["The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048627", "l": "myoblast development", "d": ["The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019896", "l": "axonal transport of mitochondrion", "d": ["The directed movement of mitochondria along microtubules in nerve cell axons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000690", "l": "regulation of cardiac muscle cell myoblast differentiation", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036018", "l": "cellular response to erythropoietin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051595", "l": "response to methylglyoxal", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072241", "l": "metanephric DCT cell development", "d": ["The process whose specific outcome is the progression of a metanephric distal convoluted tubule cell over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903918", "l": "regulation of actin filament severing", "d": ["Any process that modulates the frequency, rate or extent of actin filament severing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042857", "l": "chrysobactin metabolic process", "d": ["The chemical reactions and pathways involving the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.260243218047506", "identifiers": [{"i": "GO:0090174", "l": "organelle membrane fusion", "d": ["The joining of two lipid bilayers to form a single organelle membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140743", "l": "regulation of lncRNA transcription", "d": ["Any process that modulates the frequency, rate or extent of the synthesis of a lncRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021791", "l": "chemoattraction of branchiomotor neuron axon in branchial arch mesenchyme", "d": ["The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000857", "l": "positive regulation of mineralocorticoid secretion", "d": ["Any process that activates or increases the frequency, rate or extent of mineralocorticoid secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035600", "l": "tRNA methylthiolation", "d": ["The addition of a methylthioether group (-SCH3) to a nucleotide in a tRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042066", "l": "perineurial glial growth", "d": ["Glial cell growth that occurs in the perineurium, a cell layer that ensheaths projections of peripheral nerves, such as motor axons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034244", "l": "negative regulation of transcription elongation by RNA polymerase II", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031174", "l": "lifelong otolith mineralization", "d": ["The formation and growth of otoliths throughout the life of the organism. Otoliths are the large extracellular ear-stones of the fish inner ear, produced by precipitation of specific crystal forms of calcium carbonate on organic matrices. The otolith enlarges throughout the life of the fish, as layers of calcium carbonate are added."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905174", "l": "regulation of vascular associated smooth muscle cell dedifferentiation", "d": ["Any process that modulates the frequency, rate or extent of vascular smooth muscle cell dedifferentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0048144", "l": "fibroblast proliferation", "d": ["The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060100", "l": "positive regulation of phagocytosis, engulfment", "d": ["Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120151", "l": "positive regulation of mitotic actomyosin contractile ring disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009909", "l": "regulation of flower development", "d": ["Any process that modulates the frequency, rate or extent of flower development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052707", "l": "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine", "d": ["The pathway resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine from histidine. Histidine undergoes three methylations by a histidine-alpha-N-methyltransferase (EC:2.1.1.44) to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:0090287", "l": "regulation of cellular response to growth factor stimulus", "d": ["Any process that modulates the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046782", "l": "regulation of viral transcription", "d": ["Any process that modulates the frequency, rate or extent of the transcription of the viral genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002613", "l": "regulation of monocyte antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003345", "l": "proepicardium cell migration involved in pericardium morphogenesis", "d": ["The coordinated movement of a mesenchymal proepicardial cell to the surface of the developing heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0009107", "l": "lipoate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901697", "l": "olivetolic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of olivetolic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903468", "l": "positive regulation of DNA replication initiation", "d": ["Any process that activates or increases the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034442", "l": "regulation of lipoprotein oxidation", "d": ["Any process that modulates the frequency, rate or extent of lipoprotein oxidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046665", "l": "amnioserosa maintenance", "d": ["Maintenance of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0090497", "l": "mesenchymal cell migration", "d": ["The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900985", "l": "vindoline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of vindoline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032981", "l": "mitochondrial respiratory chain complex I assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0006221", "l": "pyrimidine nucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045311", "l": "invasive growth in response to pheromone", "d": ["The growth of colonies in filamentous chains of cells as a result of a pheromone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061533", "l": "norepinephrine secretion, neurotransmission", "d": ["The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061183", "l": "regulation of dermatome development", "d": ["Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904868", "l": "telomerase catalytic core complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a telomerase catalytic core complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061476", "l": "response to anticoagulant", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticoagulant stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071996", "l": "glutathione transmembrane import into vacuole", "d": ["The directed movement of glutathione into the vacuole across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900819", "l": "orlandin metabolic process", "d": ["The chemical reactions and pathways involving orlandin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905635", "l": "FACT complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a FACT complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032113", "l": "regulation of carbohydrate phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of carbohydrate phosphatase activity, the catalysis of the hydrolysis of phosphate from a carbohydrate phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904336", "l": "negative regulation of ductus arteriosus closure", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ductus arteriosus closure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042574", "l": "retinal metabolic process", "d": ["The chemical reactions and pathways involving retinal, a compound that plays an important role in the visual process in most vertebrates. In the retina, retinal combines with opsins to form visual pigments. Retinal is one of the forms of vitamin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.281967957033203", "identifiers": [{"i": "GO:1902680", "l": "positive regulation of RNA biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0014873", "l": "response to muscle activity involved in regulation of muscle adaptation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus. This process occurs as part of the regulation of muscle adaptation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1901403", "l": "positive regulation of tetrapyrrole metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018260", "l": "protein guanylylation", "d": ["The addition of phospho-guanosine to a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.437453848678771", "identifiers": [{"i": "GO:0072657", "l": "protein localization to membrane", "d": ["A process in which a protein is transported to, or maintained in, a specific location in a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902068", "l": "regulation of sphingolipid mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of sphingolipid signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035750", "l": "protein localization to myelin sheath abaxonal region", "d": ["Any process in which a protein is transported to, and/or maintained in, the abaxonal region of the myelin sheath. The abaxonal region is the region of the myelin sheath furthest from the axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901039", "l": "regulation of peptide antigen transport", "d": ["Any process that modulates the frequency, rate or extent of peptide antigen transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1903715", "l": "regulation of aerobic respiration", "d": ["Any process that modulates the frequency, rate or extent of aerobic respiration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044349", "l": "DNA excision", "d": ["The removal of a section of DNA from a larger DNA molecule by the making of dual incisions that flank the section to be excised."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.124646994401843", "identifiers": [{"i": "GO:0002274", "l": "myeloid leukocyte activation", "d": ["A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0003229", "l": "ventricular cardiac muscle tissue development", "d": ["The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009647", "l": "skotomorphogenesis", "d": ["The control of plant growth, development, and differentiation in response to growth in darkness."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046473", "l": "phosphatidic acid metabolic process", "d": ["The chemical reactions and pathways involving phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0043385", "l": "mycotoxin metabolic process", "d": ["The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035348", "l": "acetyl-CoA transmembrane transport", "d": ["The process in which acetyl-CoA is transported across a membrane. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075278", "l": "negative regulation of telium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008542", "l": "visual learning", "d": ["Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.964041781481406", "identifiers": [{"i": "GO:0006629", "l": "lipid metabolic process", "d": ["The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015796", "l": "galactitol transmembrane transport", "d": ["The directed movement of galactitol across a membrane. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060963", "l": "positive regulation of ribosomal protein gene transcription by RNA polymerase II", "d": ["Any process that increases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903216", "l": "regulation of protein processing involved in protein targeting to mitochondrion", "d": ["Any process that modulates the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031534", "l": "minus-end directed microtubule sliding", "d": ["The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000556", "l": "positive regulation of T-helper 1 cell cytokine production", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 1 cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015700", "l": "arsenite transport", "d": ["The directed movement of arsenite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070294", "l": "renal sodium ion absorption", "d": ["A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0140454", "l": "protein aggregate center assembly", "d": ["The reversible aggregation of misfolded proteins and chaperones, formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900915", "l": "negative regulation of octadecene biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of octadecene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072738", "l": "cellular response to diamide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904471", "l": "negative regulation of endothelin production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelin production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071975", "l": "cell swimming", "d": ["Cell motility that results in the smooth movement of a cell through a liquid medium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106220", "l": "pyocyanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrocyanin, an iminium betaine that is 5-methylphenazin-5-ium which is substituted at position 1 by an oxidanidyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901125", "l": "candicidin metabolic process", "d": ["The chemical reactions and pathways involving candicidin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.664775500092716", "identifiers": [{"i": "GO:0051258", "l": "protein polymerization", "d": ["The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140141", "l": "mitochondrial potassium ion transmembrane transport", "d": ["The process in which a potassium ion is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0150098", "l": "glial cell-neuron signaling", "d": ["Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signalling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003356", "l": "regulation of cilium beat frequency", "d": ["Any process that modulates the frequency of cilium movement, the directed, self-propelled movement of a cilium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.179240568382518", "identifiers": [{"i": "GO:0009056", "l": "catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006550", "l": "isoleucine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110097", "l": "regulation of calcium import into the mitochondrion", "d": ["Any process that modulates the frequency, rate or extent of calcium import into the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072020", "l": "proximal straight tubule development", "d": ["The process whose specific outcome is the progression of the proximal straight tubule over time, from its formation to the mature structure. The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "36.25435738894609", "identifiers": [{"i": "GO:0051179", "l": "localization", "d": ["Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072308", "l": "negative regulation of metanephric nephron tubule epithelial cell differentiation", "d": ["Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021905", "l": "forebrain-midbrain boundary formation", "d": ["The process whose specific outcome is the creation of the forebrain-midbrain boundary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0006474", "l": "N-terminal protein amino acid acetylation", "d": ["The acetylation of the N-terminal amino acid of proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099642", "l": "retrograde axonal protein transport", "d": ["The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061142", "l": "mesothelial-mesenchymal cell signaling involved in early lung development", "d": ["Any process that mediates the transfer of information from a mesothelial cell to an epithelial cell and contributes to the development of the lung."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901133", "l": "kanamycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of kanamycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0099590", "l": "neurotransmitter receptor internalization", "d": ["A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0042174", "l": "negative regulation of sporulation resulting in formation of a cellular spore", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.569439710577498", "identifiers": [{"i": "GO:1903320", "l": "regulation of protein modification by small protein conjugation or removal", "d": ["Any process that modulates the frequency, rate or extent of protein modification by small protein conjugation or removal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900793", "l": "shamixanthone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of shamixanthone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903551", "l": "regulation of extracellular exosome assembly", "d": ["Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002660", "l": "positive regulation of peripheral tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002471", "l": "monocyte antigen processing and presentation", "d": ["The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046709", "l": "IDP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of IDP, inosine 5'-diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0035482", "l": "gastric motility", "d": ["The spontaneous peristaltic movements of the stomach that aid in digestion, moving food through the stomach and out through the pyloric sphincter into the duodenum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010254", "l": "nectary development", "d": ["The process whose specific outcome is the progression of the floral nectaries over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036070", "l": "light-independent bacteriochlorophyll biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the absence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060858", "l": "vesicle-mediated transport involved in floral organ abscission", "d": ["The directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002750", "l": "antigen processing and presentation following macropinocytosis", "d": ["Antigen processing and presentation which is initiated by uptake of antigen via macropinocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071572", "l": "histone H3-K56 deacetylation", "d": ["The modification of histone H3 by the removal of an acetyl group from lysine at position 56 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0030301", "l": "cholesterol transport", "d": ["The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045228", "l": "slime layer polysaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polysaccharides in the slime layer, a diffused layer of polysaccharide exterior to the bacterial cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021556", "l": "central nervous system formation", "d": ["The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905553", "l": "regulation of blood vessel branching", "d": ["Any process that modulates the frequency, rate or extent of blood vessel branching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0046247", "l": "terpene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048036", "l": "central complex development", "d": ["The process whose specific outcome is the progression of the central complex over time, from its formation to the mature structure. The central complex region of the insect brain is thought to be crucial for control of locomotive behavior. Located in the middle of the two protocerebral hemispheres, it comprises four neuropilar regions, the fan-shaped body, the ellipsoid body, the protocerebral bridge and the paired noduli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003274", "l": "endocardial cushion fusion", "d": ["The cell-cell adhesion process of mesenchymal cardiac cushion cells that contributes to the process of cushion shaping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:1902440", "l": "protein localization to mitotic spindle pole body", "d": ["A process in which a protein is transported to, or maintained in, a location within a mitotic spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0048884", "l": "neuromast development", "d": ["The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901314", "l": "regulation of histone H2A K63-linked ubiquitination", "d": ["Any process that modulates the frequency, rate or extent of histone H2A K63-linked ubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090618", "l": "DNA clamp unloading", "d": ["The process of removing the PCNA complex from DNA when Okazaki fragments are completed or the replication fork terminates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060130", "l": "thyroid-stimulating hormone-secreting cell development", "d": ["The process whose specific outcome is the progression of a thyroid-stimulating hormone-secreting cell over time, from its formation to the mature structure. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000770", "l": "negative regulation of establishment or maintenance of cell polarity regulating cell shape", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0021546", "l": "rhombomere development", "d": ["The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0097081", "l": "vascular associated smooth muscle cell fate commitment", "d": ["The commitment of cells to a vascular smooth muscle cell fate and their capacity to differentiate into vascular smooth muscle cells. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060502", "l": "epithelial cell proliferation involved in lung morphogenesis", "d": ["The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902794", "l": "siRNA-independent facultative heterochromatin formation", "d": ["The formation of facultative heterochromatin into a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process independent of small interfering RNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901075", "l": "negative regulation of engulfment of apoptotic cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of engulfment of apoptotic cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046628", "l": "positive regulation of insulin receptor signaling pathway", "d": ["Any process that increases the frequency, rate or extent of insulin receptor signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060885", "l": "clearance of cells from fusion plate by apoptotic process", "d": ["Any apoptotic process that contributes to the shaping of the semicircular canal by removing cells in the fusion plate, forming the loops of the canals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902744", "l": "negative regulation of lamellipodium organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.356779217613806", "identifiers": [{"i": "GO:0003341", "l": "cilium movement", "d": ["The directed, self-propelled movement of a cilium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031540", "l": "regulation of anthocyanin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035038", "l": "female pronucleus assembly", "d": ["Assembly of the haploid nucleus of the unfertilized egg."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.021355091518231", "identifiers": [{"i": "GO:0003333", "l": "amino acid transmembrane transport", "d": ["The process in which an amino acid is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072201", "l": "negative regulation of mesenchymal cell proliferation", "d": ["Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045812", "l": "negative regulation of Wnt signaling pathway, calcium modulating pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0002825", "l": "regulation of T-helper 1 type immune response", "d": ["Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006663", "l": "platelet activating factor biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990414", "l": "replication-born double-strand break repair via sister chromatid exchange", "d": ["The repair of a replication-born double-strand DNA break in which the DNA molecule is repaired using the homologous sequence of the sister chromatid which serves as a template to repair the breaks."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090521", "l": "podocyte cell migration", "d": ["The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000354", "l": "cis assembly of pre-catalytic spliceosome", "d": ["Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901620", "l": "regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning", "d": ["Any process that modulates the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016348", "l": "imaginal disc-derived leg joint morphogenesis", "d": ["The process in which the anatomical structures of an imaginal disc-derived leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140861", "l": "DNA repair-dependent chromatin remodeling", "d": ["A chromatin remodeling process that allows DNA repair enzyme to access genomic DNA and repair DNA lesions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.250759876326711", "identifiers": [{"i": "GO:0002696", "l": "positive regulation of leukocyte activation", "d": ["Any process that activates or increases the frequency, rate, or extent of leukocyte activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0042048", "l": "olfactory behavior", "d": ["The behavior of an organism in response to an odor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001920", "l": "negative regulation of receptor recycling", "d": ["Any process that stops, prevents, or reduces the rate of receptor recycling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0072156", "l": "distal tubule morphogenesis", "d": ["The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902584", "l": "positive regulation of response to water deprivation", "d": ["Any process that activates or increases the frequency, rate or extent of response to water deprivation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:1901796", "l": "regulation of signal transduction by p53 class mediator", "d": ["Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048716", "l": "labrum morphogenesis", "d": ["The process in which the anatomical structures of labrum are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0015847", "l": "putrescine transport", "d": ["The directed movement of putrescine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0072235", "l": "metanephric distal tubule development", "d": ["The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901755", "l": "vitamin D3 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of vitamin D3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900706", "l": "positive regulation of siderophore biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of siderophore biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006847", "l": "plasma membrane acetate transport", "d": ["The directed movement of acetate across a plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901453", "l": "positive regulation of response to benzene", "d": ["Any process that activates or increases the frequency, rate or extent of response to benzene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007021", "l": "tubulin complex assembly", "d": ["The aggregation and bonding together of alpha- and beta-tubulin to form a tubulin heterodimer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905240", "l": "negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905294", "l": "positive regulation of neural crest cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140729", "l": "self-resistance to endogenously produced metabolite", "d": ["A process that reduces or removes the toxicity of an endogenously produced substance. Mechanisms of resistance to endogenously produced compounds include modification the compound, export, sequestration, or mutations in the target enzyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903337", "l": "positive regulation of vacuolar transport", "d": ["Any process that activates or increases the frequency, rate or extent of vacuolar transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042620", "l": "poly(3-hydroxyalkanoate) metabolic process", "d": ["The chemical reactions and pathways involving poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048628", "l": "myoblast maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.261087039309942", "identifiers": [{"i": "GO:0045596", "l": "negative regulation of cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0032907", "l": "transforming growth factor beta3 production", "d": ["The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905919", "l": "negative regulation of CoA-transferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CoA-transferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080092", "l": "regulation of pollen tube growth", "d": ["Any process that modulates the frequency, rate or extent of pollen tube growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904321", "l": "response to forskolin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099145", "l": "regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane", "d": ["Any process that modulates the frequency, rate or extent of exocytic fusion of neurotransmitter receptor containing vesicles into the postsynaptic membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018406", "l": "protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan", "d": ["The glycosylation of a peptidyl-tryptophan residue by the transfer of alpha-mannopyranose from dolichyl-activated mannose to the indole ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0016338", "l": "calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules", "d": ["The attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003086", "l": "regulation of systemic arterial blood pressure by local renal renin-angiotensin", "d": ["The process in which angiotensinogen metabolites in the kidney modulate the force with which blood passes through the renal circulatory system. The process begins when renin cleaves angiotensinogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019372", "l": "lipoxygenase pathway", "d": ["The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0106288", "l": "regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA", "d": ["Any process that modulates the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.207992593949683", "identifiers": [{"i": "GO:0000747", "l": "conjugation with cellular fusion", "d": ["A conjugation process that results in the union of cellular and genetic information from compatible mating types. An example of this process is found in Saccharomyces cerevisiae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060942", "l": "neural crest-derived cardiac fibroblast cell differentiation", "d": ["The process in which a neural crest cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905856", "l": "negative regulation of pentose-phosphate shunt", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pentose-phosphate shunt."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.642927237245431", "identifiers": [{"i": "GO:0007565", "l": "female pregnancy", "d": ["The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901915", "l": "positive regulation of capsule organization", "d": ["Any process that activates or increases the frequency, rate or extent of capsule organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0035967", "l": "cellular response to topologically incorrect protein", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033563", "l": "dorsal/ventral axon guidance", "d": ["The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070393", "l": "teichoic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090419", "l": "negative regulation of transcription involved in G2/M transition of mitotic cell cycle", "d": ["Any process that inhibits or decreases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000314", "l": "negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903331", "l": "positive regulation of iron-sulfur cluster assembly", "d": ["Any process that activates or increases the frequency, rate or extent of iron-sulfur cluster assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0002544", "l": "chronic inflammatory response", "d": ["Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0070099", "l": "regulation of chemokine-mediated signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of a chemokine-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903890", "l": "positive regulation of plant epidermal cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of plant epidermal cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021552", "l": "midbrain-hindbrain boundary structural organization", "d": ["The process that contributes to the act of creating the structural organization of the midbrain-hindbrain boundary structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051600", "l": "regulation of endocytosis by exocyst localization", "d": ["Any process in which an exocyst is transported to, or maintained in, a specific location that results in the modulation of endocytosis. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099644", "l": "protein localization to presynaptic membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within a presynaptic membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990768", "l": "gastric mucosal blood circulation", "d": ["The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010572", "l": "positive regulation of platelet activation", "d": ["Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0000965", "l": "mitochondrial RNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046722", "l": "lactic acid secretion", "d": ["The controlled release of lactic acid, 2-hydroxypropanoic acid, by a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0043300", "l": "regulation of leukocyte degranulation", "d": ["Any process that modulates the frequency, rate, or extent of leukocyte degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903219", "l": "negative regulation of malate dehydrogenase (decarboxylating) (NADP+) activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051005", "l": "negative regulation of lipoprotein lipase activity", "d": ["Any process that stops or reduces the activity of the enzyme lipoprotein lipase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120138", "l": "regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150099", "l": "neuron-glial cell signaling", "d": ["Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signalling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.115164699299683", "identifiers": [{"i": "GO:0019233", "l": "sensory perception of pain", "d": ["The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031290", "l": "retinal ganglion cell axon guidance", "d": ["The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:0045446", "l": "endothelial cell differentiation", "d": ["The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021562", "l": "vestibulocochlear nerve development", "d": ["The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060009", "l": "Sertoli cell development", "d": ["The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003292", "l": "cardiac septum cell differentiation", "d": ["The process in which an endocardial cushion cell becomes a cell of a cardiac septum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0002237", "l": "response to molecule of bacterial origin", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045659", "l": "negative regulation of neutrophil differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of neutrophil differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046442", "l": "aerobactin metabolic process", "d": ["The chemical reactions and pathways involving aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009136", "l": "purine nucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0010464", "l": "regulation of mesenchymal cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.096227290700369", "identifiers": [{"i": "GO:0061564", "l": "axon development", "d": ["The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060588", "l": "negative regulation of lipoprotein lipid oxidation", "d": ["Any process that decreases the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036392", "l": "chemokine (C-C motif) ligand 20 production", "d": ["The appearance of chemokine (C-C motif) ligand 20 (CCL20) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0007563", "l": "regulation of eclosion", "d": ["Any process that modulates the frequency, rate or extent of the emergence of an insect from a pupa-case or of a larva from an egg."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019261", "l": "1,4-dichlorobenzene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0002516", "l": "B cell deletion", "d": ["The apoptotic death of B cells which is part of B cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0015995", "l": "chlorophyll biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000947", "l": "positive regulation of amylopectin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of amylopectin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.760111289607934", "identifiers": [{"i": "GO:0040034", "l": "regulation of development, heterochronic", "d": ["Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090058", "l": "metaxylem development", "d": ["The process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904763", "l": "chaperone-mediated autophagy translocation complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a chaperone-mediated autophagy translocation complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900586", "l": "arugosin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of arugosin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0052804", "l": "nitroimidazole catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nitroimidazoles, imidazole derivatives with a nitro group attached to one ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0061985", "l": "carbon catabolite repression", "d": ["A process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of the metabolism of other carbon sources."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010662", "l": "regulation of striated muscle cell apoptotic process", "d": ["Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0072070", "l": "loop of Henle development", "d": ["The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.990900157612501", "identifiers": [{"i": "GO:0032505", "l": "reproduction of a single-celled organism", "d": ["The biological process in which new individuals are produced by one or two single-celled organisms. The new individuals inherit some proportion of their genetic material from the parent or parents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070328", "l": "triglyceride homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042696", "l": "menarche", "d": ["The beginning of the menstrual cycle; the first menstrual cycle in an individual."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905425", "l": "negative regulation of Wnt-mediated midbrain dopaminergic neuron differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905123", "l": "regulation of glucosylceramidase activity", "d": ["Any process that modulates the frequency, rate or extent of glucosylceramidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006068", "l": "ethanol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0044806", "l": "G-quadruplex DNA unwinding", "d": ["The process by which G-quadruplex (also known as G4) DNA, which is a four-stranded DNA structure held together by guanine base pairing, is unwound or 'melted'."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010656", "l": "negative regulation of muscle cell apoptotic process", "d": ["Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042186", "l": "o-xylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090051", "l": "negative regulation of cell migration involved in sprouting angiogenesis", "d": ["Any process that decreases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010864", "l": "positive regulation of protein histidine kinase activity", "d": ["Any process that increases the frequency, rate or extent of protein histidine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0080094", "l": "response to trehalose-6-phosphate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097070", "l": "ductus arteriosus closure", "d": ["The morphogenesis process in which the ductus arteriosus changes to no longer permit blood flow after birth. The ductus arteriosus is the shunt between the aorta and the pulmonary artery which allows blood to bypass the fetus' lungs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120266", "l": "positive regulation of chromosome attachment to the nuclear envelope", "d": ["Any process that activates or increases the frequency, rate or extent of the chromosome attachment to the nuclear envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003335", "l": "corneocyte development", "d": ["The process whose specific outcome is the progression of the corneocyte over time, from its formation to the mature structure. A corneocyte is the last stage of development of a keratinocyte where the keratinocyte flattens, loses its nucleus and eventually delaminates from the epidermis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042684", "l": "cardioblast cell fate commitment", "d": ["The process in which a cell becomes committed to becoming a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019709", "l": "iron incorporation into iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide", "d": ["The incorporation of iron into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0097252", "l": "oligodendrocyte apoptotic process", "d": ["Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.790184063220053", "identifiers": [{"i": "GO:1901987", "l": "regulation of cell cycle phase transition", "d": ["Any process that modulates the frequency, rate or extent of cell cycle phase transition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007294", "l": "germarium-derived oocyte fate determination", "d": ["The cell fate determination process in which a germarium-derived cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0048086", "l": "negative regulation of developmental pigmentation", "d": ["Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.003741351937961", "identifiers": [{"i": "GO:0061546", "l": "tyramine secretion, neurotransmission", "d": ["The regulated release of a tyramine by a cell in which the tyramine acts as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048373", "l": "lateral mesodermal cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039010", "l": "specification of pronephric distal tubule identity", "d": ["The process in which the distal tubule of the pronephric nephron acquires its identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0072089", "l": "stem cell proliferation", "d": ["The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0021889", "l": "olfactory bulb interneuron differentiation", "d": ["The process in which a neuroblast acquires specialized features of an interneuron residing in the olfactory bulb."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0050729", "l": "positive regulation of inflammatory response", "d": ["Any process that activates or increases the frequency, rate or extent of the inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0016321", "l": "female meiosis chromosome segregation", "d": ["The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0050928", "l": "negative regulation of positive chemotaxis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006786", "l": "heme C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heme c, a derivative of heme found in cytochromes c, b4, and f."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0045988", "l": "negative regulation of striated muscle contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043098", "l": "purine deoxyribonucleoside salvage", "d": ["Any process which produces a purine deoxyribonucleoside from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035028", "l": "leading edge cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019043", "l": "establishment of viral latency", "d": ["A process by which a virus establishes a latent state within its host, either as an integrated provirus within the host genome or as an episome, where viral genome remains in the cytoplasm or nucleus as distinct objects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903408", "l": "positive regulation of P-type sodium:potassium-exchanging transporter activity", "d": ["Any process that activates or increases the frequency, rate or extent of sodium:potassium-exchanging ATPase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0140975", "l": "disruption of cellular anatomical structure in another organism", "d": ["The disruption of a cellular component of another organism, leading to damage or temporary subversion of that structure. In some cases this can cause malfunctioning of the cells and death of the target organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0009900", "l": "dehiscence", "d": ["The opening of an anther, fruit or other structure, which permits the escape of reproductive bodies contained within it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061295", "l": "regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis", "d": ["Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905036", "l": "positive regulation of antifungal innate immune response", "d": ["Any process that activates or increases the frequency, rate or extent of an antifungal innate immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990379", "l": "lipid transport across blood-brain barrier", "d": ["The directed movement of lipid molecules passing through the blood-brain barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019071", "l": "viral DNA cleavage involved in viral genome maturation", "d": ["The cleavage of viral DNA into singular functional units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021667", "l": "rhombomere 6 morphogenesis", "d": ["The process in which the anatomical structure of rhombomere 6 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0120028", "l": "negative regulation of osmosensory signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045684", "l": "positive regulation of epidermis development", "d": ["Any process that activates or increases the frequency, rate or extent of epidermis development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900340", "l": "negative regulation of methane biosynthetic process from formic acid", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from formic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072041", "l": "positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis", "d": ["Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0061718", "l": "glucose catabolic process to pyruvate", "d": ["The chemical reactions and pathways resulting in the breakdown of glucose, with the production of pyruvate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021711", "l": "cerebellar unipolar brush cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature unipolar brush cell in the cerebellum. Differentiation includes the processes involved in commitment of a neuroblast to a unipolar brush cell fate. A unipolar brush cell is a glutamatergic interneuron found in the cerebellar cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902938", "l": "regulation of intracellular calcium activated chloride channel activity", "d": ["Any process that modulates the frequency, rate or extent of intracellular calcium activated chloride channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071995", "l": "phytochelatin import into vacuole", "d": ["The directed movement of phytochelatins into the vacuole. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0007368", "l": "determination of left/right symmetry", "d": ["The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:1901992", "l": "positive regulation of mitotic cell cycle phase transition", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cell cycle phase transition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090189", "l": "regulation of branching involved in ureteric bud morphogenesis", "d": ["Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071970", "l": "fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in fungal cell walls."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042037", "l": "peptidyl-histidine methylation, to form pros-methylhistidine", "d": ["The methylation of peptidyl-L-histidine to form peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050980", "l": "detection of light stimulus involved in magnetoreception", "d": ["The series of events involved in magnetoception in which a light stimulus is received and converted into a molecular signal. Downstream processing of the light information in addition to other sensory data allows organisms to perceive the orientation of a magnetic field."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033476", "l": "indoleacetic acid ester conjugate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an a sugar or polyol through an ester bond."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0061726", "l": "mitochondrion disassembly", "d": ["The disaggregation of a mitochondrion into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002913", "l": "positive regulation of lymphocyte anergy", "d": ["Any process that activates or increases the frequency, rate, or extent of lymphocyte anergy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032939", "l": "positive regulation of translation in response to oxidative stress", "d": ["Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.794851102982726", "identifiers": [{"i": "GO:0048872", "l": "homeostasis of number of cells", "d": ["Any biological process involved in the maintenance of the steady-state number of cells within a population of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033355", "l": "ascorbate glutathione cycle", "d": ["A cyclic series of interconversions involving L-ascorbate and glutathione that scavenges hydrogen peroxide and reduces it to water, with concomitant oxidation of NADPH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0034311", "l": "diol metabolic process", "d": ["The chemical reactions and pathways involving a diol, a compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048931", "l": "posterior lateral line nerve glial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902321", "l": "methyl-branched fatty acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of methyl-branched fatty acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045679", "l": "regulation of R8 cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of R8 differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007537", "l": "inactivation of recombination (HML)", "d": ["The inactivation of recombination at sequences around a mating type donor locus, with the consequence that the other donor is the only one available for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010588", "l": "cotyledon vascular tissue pattern formation", "d": ["Vascular tissue pattern formation as it occurs in the cotyledon of vascular plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060699", "l": "regulation of endoribonuclease activity", "d": ["Any process that modulates the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019234", "l": "sensory perception of fast pain", "d": ["The series of events required for an organism to receive a fast pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Fast pain is often subjectively described as a sharp or stabbing pain; in humans, the signals from a fast pain stimulus are perceived and relayed along myelinated A-delta fibers to the central nervous system, reaching their target in about 0.1 seconds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034031", "l": "ribonucleoside bisphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051616", "l": "regulation of histamine uptake", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter histamine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071227", "l": "cellular response to molecule of oomycetes origin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.426153789046865", "identifiers": [{"i": "GO:0032409", "l": "regulation of transporter activity", "d": ["Any process that modulates the activity of a transporter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0032631", "l": "interleukin-27 production", "d": ["The appearance of interleukin-27 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035350", "l": "FAD transmembrane transport", "d": ["The process in which flavin-adenine dinucleotide (FAD) is transported across a membrane. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031449", "l": "regulation of slow-twitch skeletal muscle fiber contraction", "d": ["Any process that modulates the frequency, rate or extent of slow-twitch skeletal muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1904847", "l": "regulation of cell chemotaxis to fibroblast growth factor", "d": ["Any process that modulates the frequency, rate or extent of cell chemotaxis to fibroblast growth factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900597", "l": "demethylkotanin metabolic process", "d": ["The chemical reactions and pathways involving demethylkotanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034115", "l": "negative regulation of heterotypic cell-cell adhesion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046296", "l": "glycolate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycolate, the anion of hydroxyethanoic acid (glycolic acid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071401", "l": "cellular response to triglyceride", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0072173", "l": "metanephric tubule morphogenesis", "d": ["The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0110126", "l": "phloem loading", "d": ["The process of loading solutes into the sieve tube or companion cell of the phloem for long distance transport from source to sink."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021763", "l": "subthalamic nucleus development", "d": ["The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.187403162058388", "identifiers": [{"i": "GO:0060361", "l": "flight", "d": ["Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0098903", "l": "regulation of membrane repolarization during action potential", "d": ["Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061989", "l": "sperm karyosome formation", "d": ["The chromosome organization process in which meiotic chromosomes in the spem nucleus cluster together to form a compact spherical structure called the karyosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900141", "l": "regulation of oligodendrocyte apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090059", "l": "protoxylem development", "d": ["The process whose specific outcome is the progression of the protoxylem over time, from its formation to the mature structure. The protoxylem comprises the first formed elements of the primary xylem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.381173084437549", "identifiers": [{"i": "GO:0071214", "l": "cellular response to abiotic stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904961", "l": "quiescent center organization", "d": ["The process that contributes to the act of creating the structural organization of the quiescent center. This process pertains to the physical shaping of a rudimentary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000435", "l": "positive regulation of transcription from RNA polymerase II promoter by galactose", "d": ["Any process involving galactose that activates or increases the rate of transcription from an RNA polymerase II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045874", "l": "positive regulation of sevenless signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the sevenless signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140531", "l": "regulation of osmosensory signaling MAPK cascade", "d": ["Any process that modulates the frequency, rate or extent of osmosensory signaling MAPK cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010402", "l": "pectic arabinan metabolic process", "d": ["The chemical reactions and pathways involving pectic arabinan, a polymer with an alpha-(1->5)-linked L-arabinofuranose (Araf) backbone that can be substituted with Araf-alpha-(1->2)-, Araf-alpha-(1->3)-, and/or Araf-alpha-(1->3)-Araf-alpha-(1->3)-side chains. Arabinan can be found as a side chain of the pectin rhamnogalacturonan I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070927", "l": "negative regulation of ATP:ADP antiporter activity", "d": ["Any process that stops or reduces the activity of an ATP:ADP antiporter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051621", "l": "regulation of norepinephrine uptake", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061297", "l": "positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis", "d": ["Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0016264", "l": "gap junction assembly", "d": ["Assembly of gap junctions, which are found in most animal tissues, and serve as direct connections between the cytoplasms of adjacent cells. They provide open channels through the plasma membrane, allowing ions and small molecules (less than approximately a thousand daltons) to diffuse freely between neighboring cells, but preventing the passage of proteins and nucleic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900993", "l": "(-)-secologanin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (-)-secologanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015754", "l": "allose transmembrane transport", "d": ["The process in which allose is transported across a lipid bilayer, from one side of a membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0042868", "l": "antisense RNA metabolic process", "d": ["The chemical reactions and pathways involving antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042550", "l": "photosystem I stabilization", "d": ["The stabilization of the photosystem I protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "43.429740795491313", "identifiers": [{"i": "GO:0071702", "l": "organic substance transport", "d": ["The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0016138", "l": "glycoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902873", "l": "negative regulation of horizontal cell localization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of horizontal cell localization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904515", "l": "positive regulation of TORC2 signaling", "d": ["Any process that activates or increases the frequency, rate or extent of TORC2 signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0016081", "l": "synaptic vesicle docking", "d": ["The initial (indirect) attachment of a synaptic vesicle membrane to the presynaptic active zone membrane, mediated by proteins protruding from the membrane and proteins of the presynaptic active zone cytoplasmic component. Synaptic vesicle tethering is the first step in this process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901283", "l": "5,6,7,8-tetrahydromethanopterin metabolic process", "d": ["The chemical reactions and pathways involving 5,6,7,8-tetrahydromethanopterin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032656", "l": "regulation of interleukin-13 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-13 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060034", "l": "notochord cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000413", "l": "regulation of fibronectin-dependent thymocyte migration", "d": ["Any process that modulates the frequency, rate or extent of fibronectin-dependent thymocyte migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0006279", "l": "premeiotic DNA replication", "d": ["The replication of DNA that precedes meiotic cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006627", "l": "protein processing involved in protein targeting to mitochondrion", "d": ["The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090377", "l": "seed trichome initiation", "d": ["The process in which the developmental fate of an epidermal cell becomes restricted such that it will develop into a seed trichome, causing a change in the orientation of cell division in the ovule epidermis at or just before anthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061968", "l": "maintenance of left/right asymmetry", "d": ["The organization process that preserves the asymmetry in an organism's body plan or part of an organism with respect to the left and right halves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0001960", "l": "negative regulation of cytokine-mediated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097379", "l": "dorsal spinal cord interneuron posterior axon guidance", "d": ["The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the posterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048510", "l": "regulation of timing of transition from vegetative to reproductive phase", "d": ["The process controlling the point in time during development when a vegetative meristem will change its identity to become an inflorescence or floral meristem, and/or the rate at which the change occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048060", "l": "negative gravitaxis", "d": ["The directed movement of a motile cell or organism away from the source of gravity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901234", "l": "positive regulation of convergent extension involved in axis elongation", "d": ["Any process that activates or increases the frequency, rate or extent of convergent extension involved in axis elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045052", "l": "protein insertion into ER membrane by GPI attachment sequence", "d": ["A process of protein insertion into the endoplasmic reticulum (ER) membrane in which proteins become anchored to the phospholipid bilayer by a covalently attached glycosylphosphatidylinositol (GPI) molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.207992593949683", "identifiers": [{"i": "GO:0090329", "l": "regulation of DNA-templated DNA replication", "d": ["Any process that modulates the rate, frequency, or extent of DNA-templated DNA replication, the process in which new strands of DNA are synthesized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071285", "l": "cellular response to lithium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0031076", "l": "embryonic camera-type eye development", "d": ["The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902990", "l": "mitotic telomere maintenance via semi-conservative replication", "d": ["Any telomere maintenance via semi-conservative replication that is involved in mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015756", "l": "fucose transmembrane transport", "d": ["The process in which fucose is transported across a lipid bilayer, from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140195", "l": "positive regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process", "d": ["Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002014", "l": "vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure", "d": ["The vasoconstriction that is triggered by vasomotor excitation resulting from the detection of high carbon dioxide levels in the vasomotor center of the central nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015834", "l": "peptidoglycan-associated peptide transport", "d": ["The directed movement of peptidoglycan peptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060893", "l": "limb granular cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an limb granular cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001250", "l": "positive regulation of ammonia assimilation cycle", "d": ["Any process that activates or increases the frequency, rate or extent of ammonia assimilation cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003403", "l": "optic vesicle formation", "d": ["The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.958948251787156", "identifiers": [{"i": "GO:0072006", "l": "nephron development", "d": ["The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043155", "l": "negative regulation of photosynthesis, light reaction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the light-dependent reaction of photosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046062", "l": "dCDP metabolic process", "d": ["The chemical reactions and pathways involving dCDP, deoxycytidine 5'-diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0050829", "l": "defense response to Gram-negative bacterium", "d": ["Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019716", "l": "N-terminal peptidyl-alanine monomethylation", "d": ["The monomethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N-methyl-L-alanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016024", "l": "CDP-diacylglycerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.675373588411375", "identifiers": [{"i": "GO:0000956", "l": "nuclear-transcribed mRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032770", "l": "positive regulation of monooxygenase activity", "d": ["Any process that activates or increases the activity of a monooxygenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902853", "l": "negative regulation of nuclear migration during mitotic telophase", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration during mitotic telophase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990880", "l": "cellular detoxification of copper ion", "d": ["Any process that reduces or removes the toxicity of copper ions in a cell. These include transport of copper cations away from sensitive areas and to compartments or complexes whose purpose is sequestration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048671", "l": "negative regulation of collateral sprouting", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014712", "l": "positive regulation of branchiomeric skeletal muscle development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002499", "l": "proteolysis within endosome associated with antigen processing and presentation", "d": ["The hydrolysis of a peptide bond or bonds within a protein by endosomal resident proteases contributing to antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014061", "l": "regulation of norepinephrine secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904597", "l": "negative regulation of connective tissue replacement involved in inflammatory response wound healing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of wound healing connective tissue replacement, which may be replaced with fibrotic material, that occurs as part of an inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060779", "l": "secondary leaflet morphogenesis", "d": ["The process in which the secondary leaflet attains its shape. A secondary leaflet develops by branching or division of a primary leaflet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.881467751602372", "identifiers": [{"i": "GO:0007611", "l": "learning or memory", "d": ["The acquisition and processing of information and/or the storage and retrieval of this information over time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032080", "l": "negative regulation of type I site-specific deoxyribonuclease activity", "d": ["Any process that stops or reduces the rate of type I restriction endodeoxyribonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904738", "l": "vascular associated smooth muscle cell migration", "d": ["The orderly movement of a vascular associated smooth muscle cell from one site to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0090696", "l": "post-embryonic plant organ development", "d": ["Development, taking place during the post-embryonic phase of a plant tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905431", "l": "microcystin transport", "d": ["The directed movement of a microcystin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019046", "l": "release from viral latency", "d": ["The process by which a virus begins to replicate following a latency replication decision (switch)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009115", "l": "xanthine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.398694714732429", "identifiers": [{"i": "GO:0050778", "l": "positive regulation of immune response", "d": ["Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045999", "l": "negative regulation of ecdysteroid secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of ecdysteroid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0014808", "l": "release of sequestered calcium ion into cytosol by sarcoplasmic reticulum", "d": ["The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002410", "l": "plasmacytoid dendritic cell chemotaxis", "d": ["The movement of a plasmacytoid dendritic cell in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901394", "l": "positive regulation of transforming growth factor beta1 activation", "d": ["Any process that activates or increases the frequency, rate or extent of transforming growth factor beta1 activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0061537", "l": "glycine secretion, neurotransmission", "d": ["The controlled release of glycine by a cell, in which glycine acts as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007450", "l": "dorsal/ventral pattern formation, imaginal disc", "d": ["The establishment, maintenance and elaboration of the dorsal/ventral axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0021681", "l": "cerebellar granular layer development", "d": ["The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0098776", "l": "protein transport across the cell outer membrane", "d": ["The directed movement of proteins across the cell outer membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033090", "l": "positive regulation of extrathymic T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of extrathymic T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032233", "l": "positive regulation of actin filament bundle assembly", "d": ["Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.850028330009977", "identifiers": [{"i": "GO:1901990", "l": "regulation of mitotic cell cycle phase transition", "d": ["Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060611", "l": "mammary gland fat development", "d": ["The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110109", "l": "negative regulation of imaginal disc-derived wing vein specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived wing vein specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032696", "l": "negative regulation of interleukin-13 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-13 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014894", "l": "response to denervation involved in regulation of muscle adaptation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a denervation stimulus. This process occurs as part of the regulation of muscle adaptation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903863", "l": "P granule assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a P granule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006751", "l": "glutathione catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045977", "l": "positive regulation of mitotic cell cycle, embryonic", "d": ["Any process that activates or increases the frequency, rate or extent of progression through the embryonic mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051006", "l": "positive regulation of lipoprotein lipase activity", "d": ["Any process that activates or increases the activity of the enzyme lipoprotein lipase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0006390", "l": "mitochondrial transcription", "d": ["The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046826", "l": "negative regulation of protein export from nucleus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019370", "l": "leukotriene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0031455", "l": "glycine betaine metabolic process", "d": ["The chemical reactions and pathways involving glycine betaine, N-trimethylglycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0072022", "l": "descending thin limb development", "d": ["The process whose specific outcome is the progression of the descending thin limb over time, from its formation to the mature structure. The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032511", "l": "late endosome to vacuole transport via multivesicular body sorting pathway", "d": ["The directed movement of substances from endosomes to vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903542", "l": "negative regulation of exosomal secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.60886360909339", "identifiers": [{"i": "GO:0090257", "l": "regulation of muscle system process", "d": ["Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.853579598310013", "identifiers": [{"i": "GO:0097435", "l": "supramolecular fiber organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031104", "l": "dendrite regeneration", "d": ["The regrowth of dendrites in response to their loss or damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002195", "l": "2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine-tRNA biosynthesis", "d": ["The chemical reactions and pathways involved in the biosynthesis of 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine (ms2io6A), a modified nucleoside present in position 37 (adjacent to and 3' of the anticodon) of tRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097116", "l": "gephyrin clustering involved in postsynaptic density assembly", "d": ["The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030843", "l": "negative regulation of intermediate filament depolymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament depolymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070444", "l": "oligodendrocyte progenitor proliferation", "d": ["The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904902", "l": "ESCRT III complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an ESCRT III complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060874", "l": "posterior semicircular canal development", "d": ["The progession of the posterior semicircular canal from its initial formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099113", "l": "negative regulation of presynaptic cytosolic calcium concentration", "d": ["Any process that decreases the concentration of calcium ions in the presynaptic cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018153", "l": "isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine", "d": ["The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glutamine to produce N6-(L-isoglutamyl)-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001002", "l": "positive regulation of xylan catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of xylan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902860", "l": "propionyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of propionyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051597", "l": "response to methylmercury", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060452", "l": "positive regulation of cardiac muscle contraction", "d": ["Any process that increases the frequency, rate or extent of cardiac muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140321", "l": "suppression of host autophagy", "d": ["Any process in which a symbiont organism decreases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045919", "l": "positive regulation of cytolysis", "d": ["Any process that activates or increases the frequency, rate or extent of cytolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901001", "l": "negative regulation of response to salt stress", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to salt stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015719", "l": "allantoate transport", "d": ["The directed movement of allantoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901142", "l": "insulin metabolic process", "d": ["The chemical reactions and pathways involving insulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072301", "l": "regulation of metanephric glomerular mesangial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of metanephric glomerular mesangial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903388", "l": "regulation of synaptic vesicle uncoating", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle uncoating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000167", "l": "regulation of planar cell polarity pathway involved in neural tube closure", "d": ["Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048454", "l": "sepal structural organization", "d": ["The process that contributes to the act of creating the structural organization of the sepal. This process pertains to the physical shaping of a rudimentary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0010821", "l": "regulation of mitochondrion organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.086235947127733", "identifiers": [{"i": "GO:0120251", "l": "hydrocarbon biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a hydrocarbon, a compound consisting of carbon and hydrogen only."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.466824939696082", "identifiers": [{"i": "GO:0043588", "l": "skin development", "d": ["The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0030166", "l": "proteoglycan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046097", "l": "deoxyuridine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902867", "l": "negative regulation of retina development in camera-type eye", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035094", "l": "response to nicotine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090335", "l": "regulation of brown fat cell differentiation", "d": ["Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048664", "l": "neuron fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a neuron regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006797", "l": "polyphosphate metabolic process", "d": ["The chemical reactions and pathways involving a polyphosphate, the anion or salt of polyphosphoric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010550", "l": "regulation of PSII associated light-harvesting complex II catabolic process", "d": ["Any process that modulates the chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043451", "l": "alkene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046673", "l": "negative regulation of compound eye retinal cell programmed cell death", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900434", "l": "regulation of filamentous growth of a population of unicellular organisms in response to starvation", "d": ["Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160036", "l": "positive regulation of postsynaptic density assembly", "d": ["Any process that activates or increases the frequency, rate or extent of postsynaptic density assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072030", "l": "short nephron development", "d": ["The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070496", "l": "positive regulation of thrombin-activated receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071460", "l": "cellular response to cell-matrix adhesion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell-matrix adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075513", "l": "caveolin-mediated endocytosis of virus by host cell", "d": ["Any caveolin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins when material is taken up into plasma membrane caveolae - specialized lipid rafts that form 50-70 nm flask-shaped invaginations of the plasma membrane - which then pinch off to form endocytic caveolar carriers containing the virus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:2000967", "l": "negative regulation of cell wall polysaccharide catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell wall polysaccharide catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042395", "l": "ecdysis, collagen and cuticulin-based cuticle", "d": ["The shedding of the old collagen and cuticulin-based cuticle fragments during the molting cycle. Examples of this process are found in invertebrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0046416", "l": "D-amino acid metabolic process", "d": ["The chemical reactions and pathways involving D-amino acids, the D-enantiomers of amino acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061011", "l": "hepatic duct development", "d": ["The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019099", "l": "female germ-line sex determination", "d": ["The determination of sex and sexual phenotype in a female organism's germ line."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901600", "l": "strigolactone metabolic process", "d": ["The chemical reactions and pathways involving strigolactone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.421413444370778", "identifiers": [{"i": "GO:0016485", "l": "protein processing", "d": ["Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032605", "l": "hepatocyte growth factor production", "d": ["The appearance of hepatocyte growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051693", "l": "actin filament capping", "d": ["The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010875", "l": "positive regulation of cholesterol efflux", "d": ["Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904016", "l": "response to Thyroglobulin triiodothyronine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0044010", "l": "single-species biofilm formation", "d": ["A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045800", "l": "negative regulation of chitin-based cuticle tanning", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of chitin-based cuticular tanning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0001522", "l": "pseudouridine synthesis", "d": ["The intramolecular conversion of uridine to pseudouridine within an RNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903407", "l": "negative regulation of P-type sodium:potassium-exchanging transporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sodium:potassium-exchanging ATPase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904691", "l": "negative regulation of type B pancreatic cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006175", "l": "dATP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009830", "l": "cell wall modification involved in abscission", "d": ["A cellular process that results in the breakdown of the cell wall that contributes to the process of abscission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901705", "l": "L-isoleucine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-isoleucine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072117", "l": "head kidney formation", "d": ["The developmental process pertaining to the initial formation of the head kidney. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901146", "l": "mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis", "d": ["Any mesenchymal cell apoptotic process that is involved in mesonephric nephron morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0033182", "l": "regulation of histone ubiquitination", "d": ["Any process that modulates the frequency, rate or extent of the addition of a ubiquitin group to a histone protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014881", "l": "regulation of myofibril size", "d": ["Any process that modulates the size of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003224", "l": "left ventricular compact myocardium morphogenesis", "d": ["The process in which the anatomical structures of cardiac left ventricular compact myocardium are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.103692674465897", "identifiers": [{"i": "GO:0031327", "l": "negative regulation of cellular biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902627", "l": "regulation of assembly of large subunit precursor of preribosome", "d": ["Any process that modulates the frequency, rate or extent of assembly of a large subunit precursor of preribosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0046015", "l": "regulation of transcription by glucose", "d": ["Any process involving glucose that modulates the frequency, rate or extent or transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0042745", "l": "circadian sleep/wake cycle", "d": ["The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036309", "l": "protein localization to M-band", "d": ["Any process in which a protein is transported to, and/or maintained in, the M band. The M band is the midline of aligned thick filaments in a sarcomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000433", "l": "carbon catabolite repression of transcription from RNA polymerase II promoter by glucose", "d": ["A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific RNA polymerase II-transcribed genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048530", "l": "fruit morphogenesis", "d": ["The process in which the anatomical structures of a fruit are generated and organized. A fruit is a reproductive body of a seed plant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904237", "l": "positive regulation of substrate-dependent cell migration, cell attachment to substrate", "d": ["Any process that activates or increases the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0045117", "l": "azole transmembrane transport", "d": ["The directed movement of azoles, heterocyclic compounds found in many biologically important substances, across a lipid bilayer, across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900501", "l": "negative regulation of butyryl-CoA catabolic process to butyrate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butyrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018405", "l": "protein-keratan sulfate linkage via keratan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine", "d": ["Keratan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and threonine residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019928", "l": "peptide cross-linking via 3-(S-L-cysteinyl)-L-aspartic acid", "d": ["The cross-linking of a cysteine residue to an aspartic acid residue to form 3-(S-L-cysteinyl)-L-aspartic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007086", "l": "vesicle fusion with nuclear membrane involved in mitotic nuclear envelope reassembly", "d": ["The cell cycle process that results in the joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the nucleus, and contributes to mitotic nuclear envelope reassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0014832", "l": "urinary bladder smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044526", "l": "formation of peptidyl-cystine persulfide by sulphur transfer from free cysteine", "d": ["The modification of a peptidyl-cystine residue in a protein by the transfer of a sulfur atom from a free cysteine (in the process converting the free cysteine to alanine) to the peptidyl-cysteine to form peptidyl-cysteine persulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900727", "l": "osmoregulated periplasmic glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of osmoregulated periplasmic glucan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062102", "l": "female germline stem cell symmetric division", "d": ["Division of a female germline stem cell to produce two germline stem cells of the same type as the parent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060689", "l": "cell differentiation involved in salivary gland development", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014806", "l": "smooth muscle hyperplasia", "d": ["A process, occurring in smooth muscle, in which there is an increase in cell number by cell division, often leading to an increase in the size of an organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0032530", "l": "regulation of microvillus organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0061552", "l": "ganglion morphogenesis", "d": ["The process in which the anatomical structures of ganglion are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "44.120435048772805", "identifiers": [{"i": "GO:0006950", "l": "response to stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021756", "l": "striatum development", "d": ["The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1904533", "l": "regulation of telomeric loop disassembly", "d": ["Any process that modulates the frequency, rate or extent of telomeric loop disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0021898", "l": "commitment of multipotent stem cells to neuronal lineage in forebrain", "d": ["The initial commitment of cells whereby the developmental fate of a cell becomes restricted such that it will develop into some type of neuron in the forebrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902003", "l": "regulation of amyloid-beta formation", "d": ["Any process that modulates the frequency, rate or extent of amyloid-beta formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042761", "l": "very long-chain fatty acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a very long chain fatty acid, a fatty acid with an aliphatic tail of 22 or more carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0035904", "l": "aorta development", "d": ["The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007376", "l": "cephalic furrow formation", "d": ["Formation of a partial necklace of inturning tissue on the lateral sides of the embryo, along the dorsal-ventral axis. This furrow demarcates head from thorax in the developing protostome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140651", "l": "futile creatine cycle", "d": ["The phosphorylation and dephosphorylation of creatine in a futile cycle, which dissipates the high energy charge of phosphocreatine as heat without performing any mechanical or chemical work. The futile creatine cycle takes place in thermogenic fat cells and is part of adaptive thermogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002924", "l": "negative regulation of humoral immune response mediated by circulating immunoglobulin", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0043101", "l": "purine-containing compound salvage", "d": ["Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090617", "l": "mitochondrial mRNA 5'-end processing", "d": ["Any process involved in forming the mature 5' end of an mRNA molecule that derives from the mitochondrial genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902152", "l": "positive regulation of response to DNA integrity checkpoint signaling", "d": ["Any process that activates or increases the frequency, rate or extent of response to DNA integrity checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "47.56089296480954", "identifiers": [{"i": "GO:0006996", "l": "organelle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0034102", "l": "erythrocyte clearance", "d": ["The selective elimination of erythrocytes from the body by autoregulatory mechanisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032762", "l": "mast cell cytokine production", "d": ["Any process that contributes to cytokine production by a mast cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0007455", "l": "eye-antennal disc morphogenesis", "d": ["The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001801", "l": "positive regulation of type IIb hypersensitivity", "d": ["Any process that activates or increases the frequency, rate or extent of type IIb hypersensitivity, a type of inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021833", "l": "cell-matrix adhesion involved in tangential migration using cell-cell interactions", "d": ["The interaction of a cell and the extracellular matrix involved in the directed tangential movement of cells mediated by cell-cell interactions in the developing cerebral cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019571", "l": "D-arabinose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-arabinose, the D-enantiomer of arabino-pentose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900295", "l": "negative regulation of heptasaccharide transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of heptasaccharide transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0043122", "l": "regulation of I-kappaB kinase/NF-kappaB signaling", "d": ["Any process that modulates I-kappaB kinase/NF-kappaB signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070189", "l": "kynurenine metabolic process", "d": ["The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043466", "l": "pyrimidine nucleobase fermentation", "d": ["The anaerobic conversion of pyrimidine nucleobases, yielding energy in the form of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060834", "l": "oral/aboral axis specification", "d": ["The establishment, maintenance and elaboration of a line that delineates the mouth and the anus of an embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901404", "l": "regulation of tetrapyrrole catabolic process", "d": ["Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903781", "l": "positive regulation of cardiac conduction", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac conduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015814", "l": "p-aminobenzoyl-glutamate transport", "d": ["The directed movement of p-aminobenzoyl-glutamate, the anion of p-aminobenzoyl-glutamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000344", "l": "positive regulation of acrosome reaction", "d": ["Any process that activates or increases the frequency, rate or extent of the acrosome reaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0001866", "l": "NK T cell proliferation", "d": ["The expansion of a NK T cell population by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0051954", "l": "positive regulation of amine transport", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0071677", "l": "positive regulation of mononuclear cell migration", "d": ["Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0009067", "l": "aspartate family amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046836", "l": "glycolipid transport", "d": ["The directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0021527", "l": "spinal cord association neuron differentiation", "d": ["The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902216", "l": "positive regulation of interleukin-4-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-4-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0006085", "l": "acetyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090246", "l": "convergent extension involved in somitogenesis", "d": ["The morphogenetic process in which a presomitic mesoderm narrows along the left-right axis and lengthens in the rostral-caudal axis contributing to somitogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160029", "l": "kidney cortex tubule cell dedifferentiation", "d": ["The process in which a kidney cortex tubule cell (specialized epithelial cell of the kidney) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009146", "l": "purine nucleoside triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014725", "l": "regulation of extraocular skeletal muscle development", "d": ["Any process that modulates the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000965", "l": "positive regulation of cellooligosaccharide catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellooligosaccharide catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002041", "l": "intussusceptive angiogenesis", "d": ["The formation of new blood vessels as a result of the insertion and extension of lumenal tissue pillars."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000083", "l": "regulation of transcription involved in G1/S transition of mitotic cell cycle", "d": ["Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044067", "l": "modification by symbiont of host cell-cell junction", "d": ["The process in which a symbiont organism effects a change in the structure or function of its host intercellular junction, a specialized region of connection between two cells. Intercellular junction include tight junctions and adherens junctions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035124", "l": "embryonic caudal fin morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905375", "l": "cellular response to homocysteine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060526", "l": "prostate glandular acinus morphogenesis", "d": ["The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061407", "l": "positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061236", "l": "mesonephric comma-shaped body morphogenesis", "d": ["The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0001776", "l": "leukocyte homeostasis", "d": ["The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042855", "l": "eugenol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032361", "l": "pyridoxal phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905010", "l": "positive regulation of L-lysine import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of L-lysine import into cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048782", "l": "negative regulation of cyanophore differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cyanophore differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1905606", "l": "regulation of presynapse assembly", "d": ["Any process that modulates the frequency, rate or extent of presynapse assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010913", "l": "regulation of sterigmatocystin biosynthetic process", "d": ["Any process that modulates the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0042713", "l": "sperm ejaculation", "d": ["The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.943330421159466", "identifiers": [{"i": "GO:0051171", "l": "regulation of nitrogen compound metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0005991", "l": "trehalose metabolic process", "d": ["The chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0009260", "l": "ribonucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090374", "l": "oligopeptide export from mitochondrion", "d": ["The process in which an oligopeptide is transported out of the mitochondrial matrix. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901665", "l": "negative regulation of NAD+ ADP-ribosyltransferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060516", "l": "primary prostatic bud elongation", "d": ["The increase in size of the prostatic bud as it forms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030959", "l": "peptide cross-linking via 3'-(3'-L-tyrosinyl)-L-tyrosine", "d": ["The modification of two peptidyl-tyrosines to form a 3'-(3'-L-tyrosinyl)-L-tyrosine protein cross-link."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000295", "l": "regulation of hydrogen peroxide catabolic process", "d": ["Any process that modulates the frequency, rate or extent of hydrogen peroxide catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099646", "l": "neurotransmitter receptor transport, plasma membrane to endosome", "d": ["Vesicle-mediated transport of a neurotransmitter receptor vesicle from the plasma membrane to the endosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0031156", "l": "regulation of sorocarp development", "d": ["Any process that modulates the frequency, rate or extent of sorocarp development. An example of this process is found in Dictyostelium discoideum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0051969", "l": "regulation of transmission of nerve impulse", "d": ["Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000110", "l": "negative regulation of macrophage apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080172", "l": "petal epidermis patterning", "d": ["The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the cells in the petal epidermis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001018", "l": "negative regulation of retrograde axon cargo transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0045761", "l": "regulation of adenylate cyclase activity", "d": ["Any process that modulates the frequency, rate or extent of adenylate cyclase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0030707", "l": "follicle cell of egg chamber development", "d": ["The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035857", "l": "eosinophil fate specification", "d": ["The process involved in the specification of identity of an eosinophil cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905217", "l": "response to astaxanthin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045775", "l": "positive regulation of beta 2 integrin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071590", "l": "nicotinamide riboside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900441", "l": "negative regulation of filamentous growth of a population of unicellular organisms in response to neutral pH", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0006570", "l": "tyrosine metabolic process", "d": ["The chemical reactions and pathways involving tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010223", "l": "secondary shoot formation", "d": ["The process that gives rise to secondary (or auxiliary or axillary) shoots in plants. This process pertains to the initial formation of a structure from unspecified parts. These secondary shoots originate from secondary meristems initiated in the axils of leaf primordia. Axillary meristems function like the shoot apical meristem of the primary shoot initating the development of lateral organs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140748", "l": "positive regulation of regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002586", "l": "regulation of antigen processing and presentation of peptide antigen via MHC class II", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0042310", "l": "vasoconstriction", "d": ["A decrease in the diameter of blood vessels, especially arteries, due to constriction of smooth muscle cells that line the vessels, and usually causing an increase in blood pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0006521", "l": "regulation of cellular amino acid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010372", "l": "positive regulation of gibberellin biosynthetic process", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0044406", "l": "adhesion of symbiont to host", "d": ["The attachment of a symbiont to its host via either adhesion molecules, general stickiness, or other mechanisms. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903942", "l": "positive regulation of respiratory gaseous exchange", "d": ["Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904870", "l": "negative regulation of protein localization to Cajal body", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to Cajal body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032335", "l": "regulation of activin secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002939", "l": "tRNA N1-guanine methylation", "d": ["The process whereby a guanine in tRNA is methylated at position N1 of the guanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902260", "l": "negative regulation of delayed rectifier potassium channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of delayed rectifier potassium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014714", "l": "myoblast fate commitment in head", "d": ["The process, taking place in the head, whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904193", "l": "negative regulation of cholangiocyte apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039576", "l": "disruption by virus of host JAK-STAT cascade via inhibition of JAK1 activity", "d": ["Any process in which interferes with a JAK-STAT signal cascade in a host organism by reducing the activity of host JAK1 (Janus Kinase 1)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0034087", "l": "establishment of mitotic sister chromatid cohesion", "d": ["The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042339", "l": "keratan sulfate metabolic process", "d": ["The chemical reactions and pathways involving keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0070897", "l": "transcription preinitiation complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), required for transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904217", "l": "regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity", "d": ["Any process that modulates the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099611", "l": "regulation of action potential firing threshold", "d": ["Any process that regulates the potential at which an axon potential is triggered."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901174", "l": "phytoene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytoene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0062161", "l": "regulation of pyocyanine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of a pyocyanine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000676", "l": "positive regulation of type B pancreatic cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010651", "l": "negative regulation of cell communication by electrical coupling", "d": ["Any process that decreases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0048499", "l": "synaptic vesicle membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the membrane surrounding a synaptic vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016560", "l": "protein import into peroxisome matrix, docking", "d": ["The process in which a complex formed of a peroxisome targeting sequence (PTS) receptor bound to a PTS-bearing protein docks with translocation machinery in the peroxisomal membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901911", "l": "adenosine 5'-(hexahydrogen pentaphosphate) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of adenosine 5'-(hexahydrogen pentaphosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009118", "l": "regulation of nucleoside metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0016446", "l": "somatic hypermutation of immunoglobulin genes", "d": ["Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0045939", "l": "negative regulation of steroid metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.669997983625713", "identifiers": [{"i": "GO:0048863", "l": "stem cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0101025", "l": "nuclear membrane biogenesis", "d": ["The process in which a nuclear membrane is synthesized, aggregates, and bonds together."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033139", "l": "regulation of peptidyl-serine phosphorylation of STAT protein", "d": ["Any process that modulates the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010788", "l": "COPI coating of Golgi vesicle, cis-Golgi to rough ER", "d": ["The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of cis-Golgi to rough ER transport vesicles, forming a vesicle coat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0012502", "l": "induction of programmed cell death", "d": ["A process which directly activates any of the steps required for programmed cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0072711", "l": "cellular response to hydroxyurea", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0006743", "l": "ubiquinone metabolic process", "d": ["The chemical reactions and pathways involving ubiquinone, a lipid-soluble electron-transporting coenzyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007371", "l": "ventral midline determination", "d": ["The regionalization process in which the area where the ventral midline will form is specified."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0098779", "l": "positive regulation of mitophagy in response to mitochondrial depolarization", "d": ["Any process that activates or increases the frequency, rate or extent of mitophagy in response to mitochondrial depolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042337", "l": "cuticle development involved in chitin-based cuticle molting cycle", "d": ["The synthesis and deposition of a chitin-based non-cellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021796", "l": "cerebral cortex regionalization", "d": ["The regionalization process that results in the creation of areas within the cerebral cortex that will direct the behavior of cell migration and differentiation as the cortex develops."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0060887", "l": "limb epidermis development", "d": ["The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046160", "l": "heme a metabolic process", "d": ["The chemical reactions and pathways involving heme a, a derivative of heme found in cytochrome aa3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0032276", "l": "regulation of gonadotropin secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006877", "l": "intracellular cobalt ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of cobalt ions within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000772", "l": "regulation of cellular senescence", "d": ["Any process that modulates the frequency, rate or extent of cellular senescence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072560", "l": "type B pancreatic cell maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904531", "l": "positive regulation of actin filament binding", "d": ["Any process that activates or increases the frequency, rate or extent of actin filament binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035847", "l": "uterine epithelium development", "d": ["The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904022", "l": "positive regulation of G protein-coupled receptor internalization", "d": ["Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor internalization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0031392", "l": "regulation of prostaglandin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0001407", "l": "glycerophosphodiester transmembrane transport", "d": ["The process in which a glycerophosphodiester is transported across a membrane. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0051189", "l": "prosthetic group metabolic process", "d": ["The chemical reactions and pathways involving a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905489", "l": "regulation of sensory neuron axon guidance", "d": ["Any process that modulates the frequency, rate or extent of sensory neuron axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0090136", "l": "epithelial cell-cell adhesion", "d": ["The attachment of an epithelial cell to another epithelial cell via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001116", "l": "methanopterin-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a methanopterin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035761", "l": "dorsal motor nucleus of vagus nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900939", "l": "negative regulation of (Z)-nonadeca-1,14-diene metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904298", "l": "regulation of transcytosis", "d": ["Any process that modulates the frequency, rate or extent of transcytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071397", "l": "cellular response to cholesterol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075253", "l": "positive regulation of uredospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032646", "l": "regulation of hepatocyte growth factor production", "d": ["Any process that modulates the frequency, rate, or extent of hepatocyte growth factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901868", "l": "ecgonine methyl ester catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ecgonine methyl ester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032230", "l": "positive regulation of synaptic transmission, GABAergic", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903476", "l": "protein localization to cell division site involved in mitotic actomyosin contractile ring assembly", "d": ["Any protein localization to cell division site that is involved in mitotic actomyosin contractile ring assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904444", "l": "regulation of establishment of Sertoli cell barrier", "d": ["Any process that modulates the frequency, rate or extent of establishment of Sertoli cell barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048938", "l": "lateral line nerve glial cell morphogenesis involved in differentiation", "d": ["The process in which the structure of a glial cell in a lateral line nerve is generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in a lateral line nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006684", "l": "sphingomyelin metabolic process", "d": ["The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033197", "l": "response to vitamin E", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046133", "l": "pyrimidine ribonucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900104", "l": "regulation of hyaluranon cable assembly", "d": ["Any process that modulates the frequency, rate or extent of hyaluranon cable assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030002", "l": "intracellular monoatomic anion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of monoatomic anions within a cell. Monatomic anions (also called simple anions) are anions consisting of exactly one atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002036", "l": "regulation of L-glutamate import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of L-glutamate import into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010462", "l": "regulation of light-activated voltage-gated calcium channel activity", "d": ["Any process that modulates the frequency, rate or extent of light-activated voltage-gated calcium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007323", "l": "peptide pheromone maturation", "d": ["The generation of a mature, active peptide pheromone via processes unique to its processing and modification. An example of this process is found in Saccharomyces cerevisiae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0061065", "l": "regulation of dauer larval development", "d": ["Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019235", "l": "sensory perception of slow pain", "d": ["The series of events required for an organism to receive a slow pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Slow pain is often subjectively described as an aching or throbbing pain; in humans, the signals from a slow pain stimulus are perceived and relayed along unmyelinated C fibers to the central nervous system, reaching their target in about 1 second. Slow pain is often associated with tissue destruction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901809", "l": "capsanthin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of capsanthin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002031", "l": "G protein-coupled receptor internalization", "d": ["The process that results in the uptake of a G protein-coupled receptor into an endocytic vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000714", "l": "positive regulation of maintenance of meiotic sister chromatid cohesion, arms", "d": ["Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019526", "l": "pentitol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pentitols, any alditol with a chain of five carbon atoms in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1901420", "l": "negative regulation of response to alcohol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003050", "l": "regulation of systemic arterial blood pressure by atrial natriuretic peptide", "d": ["The regulation of blood pressure mediated by the signaling molecule atrial natriuretic peptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046772", "l": "viral budding from outer nuclear membrane", "d": ["The envelopment of a virus, in which the naked capsid evaginates from the host outer nuclear membrane system, thus acquiring a membrane envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0009827", "l": "plant-type cell wall modification", "d": ["The series of events leading to chemical and structural alterations of an existing cellulose and pectin-containing cell wall that can result in loosening, increased extensibility or disassembly. An example of this is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034128", "l": "negative regulation of MyD88-independent toll-like receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048693", "l": "regulation of collateral sprouting of injured axon", "d": ["Any process that modulates the frequency, rate or extent of collateral sprouting of an injured axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0090646", "l": "mitochondrial tRNA processing", "d": ["The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group, in the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099015", "l": "degradation of host chromosome by virus", "d": ["The catabolic breakdown of the DNA of a host chromosome by a virus. This occurs during infection of bacteria by some phages. It frees up a large pool of nucleoside 5'-triphophates for use in viral DNA synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0097186", "l": "amelogenesis", "d": ["The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905384", "l": "regulation of protein localization to presynapse", "d": ["Any process that modulates the frequency, rate or extent of protein localization to presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090700", "l": "maintenance of plant organ identity", "d": ["The process in which the identity of a plant organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900246", "l": "positive regulation of RIG-I signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of RIG-I signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044554", "l": "modulation of heart rate in another organism", "d": ["Any process that modulates the frequency or rate of heart contraction of another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019364", "l": "pyridine nucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:1902107", "l": "positive regulation of leukocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0003379", "l": "establishment of cell polarity involved in gastrulation cell migration", "d": ["The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090219", "l": "negative regulation of lipid kinase activity", "d": ["Any process that decreases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120164", "l": "conidium germination", "d": ["The physiological and developmental changes that occur in a conidium or asexual spore following release from dormancy up to the earliest signs of development such as swelling of conidia, adhesion and nuclear decondensation followed by hyphal growth several hours later. In many genera of plant pathogenic fungi (e.g. Magnaporthe, Colletotrichum, Ustilago), swelling of the hyphal tips to form appressorium, metabolic activities including respiration, RNA and protein synthesis and trehalose breakdown and changes in cell wall composition can be detected in conidium germination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0021576", "l": "hindbrain formation", "d": ["The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048250", "l": "iron import into the mitochondrion", "d": ["The process in which iron is transported from the cytosol into the mitochondrial matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0009163", "l": "nucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035728", "l": "response to hepatocyte growth factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.071082486141265", "identifiers": [{"i": "GO:0022037", "l": "metencephalon development", "d": ["The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0034758", "l": "positive regulation of iron ion transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902915", "l": "negative regulation of protein polyubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein polyubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090602", "l": "sieve element enucleation", "d": ["The process in which nucleated precursor cells lose their nucleus as part of sieve element differentiation. The nuclear contents are released and degraded in the cytoplasm at the same time as other organelles are rearranged and the cytosol is degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0071635", "l": "negative regulation of transforming growth factor beta production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080060", "l": "integument development", "d": ["The process whose specific outcome is the progression of the integument over time, from its formation to the mature structure. Integument is one of the layers of tissue that usually covers the ovule, enveloping the nucellus and forming the micropyle at the apex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0039709", "l": "cytoplasmic capsid assembly", "d": ["The assembly of a virus capsid that occurs in the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0090132", "l": "epithelium migration", "d": ["The process in which the population of cells that make up an epithelium undergo directed movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001110", "l": "RNA polymerase III promoter clearance", "d": ["A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase III, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0071450", "l": "cellular response to oxygen radical", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061566", "l": "CMP phosphorylation", "d": ["The process of introducing a phosphate group into CMP, cytidine monophosphate, to produce CDP. Addition of two phosphate groups produces CTP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0009085", "l": "lysine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0043281", "l": "regulation of cysteine-type endopeptidase activity involved in apoptotic process", "d": ["Any process that modulates the activity of a cysteine-type endopeptidase involved in apoptosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022017", "l": "neuroblast division in pallium", "d": ["The division of neuroblasts in the pallium. Neuroblasts are precursor cells that give rise to neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0045581", "l": "negative regulation of T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904387", "l": "cellular response to L-phenylalanine derivative", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090038", "l": "negative regulation of protein kinase C signaling", "d": ["Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0051300", "l": "spindle pole body organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB). The SPB is the microtubule organizing center in fungi, and is functionally homologous to the animal cell centrosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032378", "l": "negative regulation of intracellular lipid transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062120", "l": "LinE complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components during meiotic prophase to form a LinE complex, the protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032773", "l": "positive regulation of tyrosinase activity", "d": ["Any process that activates or increases the activity of a tyrosinase enzyme monophenol oxygenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904461", "l": "ergosteryl 3-beta-D-glucoside metabolic process", "d": ["The chemical reactions and pathways involving ergosteryl 3-beta-D-glucoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900218", "l": "negative regulation of apoptotic process involved in metanephric nephron tubule development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075291", "l": "positive regulation of aplanospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007303", "l": "cytoplasmic transport, nurse cell to oocyte", "d": ["The directed movement of cytoplasmic constituents synthesized in the nurse cells to the oocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0007499", "l": "ectoderm and mesoderm interaction", "d": ["A cell-cell signaling process occurring between the two gastrulation-generated layers of the ectoderm and the mesoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030853", "l": "negative regulation of granulocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050834", "l": "molybdenum incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide", "d": ["The incorporation of molybdenum into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043152", "l": "induction of bacterial agglutination", "d": ["Any process in which infecting bacteria are clumped together by a host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900906", "l": "negative regulation of hexadecanal metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904331", "l": "regulation of error-prone translesion synthesis", "d": ["Any process that modulates the frequency, rate or extent of error-prone translesion synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0050843", "l": "S-adenosylmethionine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0021966", "l": "corticospinal neuron axon guidance", "d": ["The process in which the migration of an axon growth cone of a neuron that is part of the corticospinal tract is directed from the cerebral cortex layer V to the spinal cord dorsal funiculus in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901905", "l": "response to tamsulosin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tamsulosin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0045332", "l": "phospholipid translocation", "d": ["The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007056", "l": "spindle assembly involved in female meiosis", "d": ["The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902241", "l": "copal-8-ol diphosphate(3-) metabolic process", "d": ["The chemical reactions and pathways involving copal-8-ol diphosphate(3-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0035935", "l": "androgen secretion", "d": ["The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045964", "l": "positive regulation of dopamine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044514", "l": "envenomation resulting in positive regulation of G protein-coupled receptor activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of G protein-coupled receptor activity in of the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001694", "l": "histamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090172", "l": "microtubule cytoskeleton organization involved in homologous chromosome segregation", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins that contributes to chromosomal pairing and precedes synapsis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904595", "l": "positive regulation of termination of RNA polymerase II transcription", "d": ["Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902725", "l": "negative regulation of satellite cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902620", "l": "positive regulation of microtubule minus-end binding", "d": ["Any process that activates or increases the frequency, rate or extent of microtubule minus-end binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1901046", "l": "positive regulation of egg-laying behavior", "d": ["Any process that activates or increases the frequency, rate or extent of oviposition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036299", "l": "non-recombinational interstrand cross-link repair", "d": ["Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that does not involve homologous DNA recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061038", "l": "uterus morphogenesis", "d": ["The process in which anatomical structures of the uterus are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0014842", "l": "regulation of skeletal muscle satellite cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle satellite cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021655", "l": "rhombomere 2 morphogenesis", "d": ["The process in which the anatomical structure of rhombomere 2 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031621", "l": "negative regulation of fever generation", "d": ["Any process that stops, prevents, or reduces the rate or extent of fever generation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055005", "l": "ventricular cardiac myofibril assembly", "d": ["The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019510", "l": "S-adenosylhomocysteine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of S-adenosylhomocysteine, forming homocysteine and then methionine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "37.214409830454265", "identifiers": [{"i": "GO:0021915", "l": "neural tube development", "d": ["The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060288", "l": "formation of a compartment boundary", "d": ["Formation of a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021568", "l": "rhombomere 2 development", "d": ["The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090538", "l": "peptide pheromone secretion", "d": ["The regulated release of a peptide pheromone from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006225", "l": "UDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP, uridine (5'-)diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902384", "l": "glycyrrhetinate metabolic process", "d": ["The chemical reactions and pathways involving glycyrrhetinate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031121", "l": "equatorial microtubule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins at the midpoint of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075186", "l": "negative regulation of infection cushion formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900079", "l": "regulation of arginine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of arginine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090309", "l": "positive regulation of DNA methylation-dependent heterochromatin formation", "d": ["Any process that increases the rate, frequency, or extent of DNA methylation-dependent heterochromatin formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021997", "l": "neural plate axis specification", "d": ["The pattern specification process in which the axes of the nervous system are established."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033396", "l": "beta-alanine biosynthetic process via 3-ureidopropionate", "d": ["The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-ureidopropionate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070656", "l": "mechanoreceptor differentiation involved in mechanosensory epithelium regeneration", "d": ["Differentiation of new mechanoreceptors to replace those lost or destroyed by injury."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071231", "l": "cellular response to folic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048447", "l": "sepal morphogenesis", "d": ["The process in which the anatomical structures of the sepal are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006785", "l": "heme B biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heme B, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0045839", "l": "negative regulation of mitotic nuclear division", "d": ["Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010158", "l": "abaxial cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an abaxial cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905766", "l": "positive regulation of protection from non-homologous end joining at telomere", "d": ["Any process that activates or increases the frequency, rate or extent of protection from non-homologous end joining at telomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051367", "l": "peptidyl-serine decanoylation", "d": ["The decanoylation of peptidyl-serine to form peptidyl-O3-decanoyl-L-serine, typical of the protein ghrelin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903761", "l": "negative regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021722", "l": "superior olivary nucleus maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0075216", "l": "positive regulation of spore encystment on host", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990683", "l": "DNA double-strand break attachment to nuclear envelope", "d": ["A process in which the DNA double-strand breaks are attached to the inner surface of the nuclear envelope proximal to the spindle pole body, or iMTOCs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0044557", "l": "relaxation of smooth muscle", "d": ["A process in which the extent of smooth muscle contraction is reduced. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0120093", "l": "regulation of peptidyl-lysine crotonylation", "d": ["Any process that modulates the frequency, rate or extent of crotonylation of a lysine residue in a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:2000058", "l": "regulation of ubiquitin-dependent protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of ubiquitin-dependent protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001074", "l": "regulation of metanephric ureteric bud development", "d": ["Any process that modulates the frequency, rate or extent of metanephric ureteric bud development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051930", "l": "regulation of sensory perception of pain", "d": ["Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905095", "l": "negative regulation of apolipoprotein A-I-mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071977", "l": "bacterial-type flagellum-dependent swimming motility", "d": ["Bacterial-type flagellum-dependent cell motility that results in the smooth movement of a cell through a liquid medium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002502", "l": "peptide antigen assembly with MHC class I protein complex", "d": ["The binding of a peptide to the antigen binding groove of an MHC class I protein complex. Class I here refers to classical class I molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904960", "l": "positive regulation of cytochrome-c oxidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of cytochrome-c oxidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900385", "l": "negative regulation of flavonol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of flavonol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000484", "l": "cleavage between SSU-rRNA and 5.8S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000635", "l": "negative regulation of primary miRNA processing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of primary microRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0009071", "l": "serine family amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905671", "l": "regulation of lysosome organization", "d": ["Any process that modulates the frequency, rate or extent of lysosome organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033354", "l": "chlorophyll cycle", "d": ["A cyclic series of interconversions involving chlorophyll a, chlorophyll b and several chlorophyllide intermediates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0031114", "l": "regulation of microtubule depolymerization", "d": ["Any process that modulates the frequency, rate or extent of microtubule depolymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990784", "l": "response to dsDNA", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007362", "l": "terminal region determination", "d": ["Specification of the terminal regions (the two non-segmented ends) of the embryo by the gap genes; exemplified in insects by the actions of huckebein and tailless gene products."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032114", "l": "regulation of glucose-6-phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of glucose-6-phosphatase activity, the catalysis of the reaction: D-glucose 6-phosphate + H2O = D-glucose + phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050747", "l": "positive regulation of lipoprotein metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904815", "l": "negative regulation of protein localization to chromosome, telomeric region", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to chromosome, telomeric region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046445", "l": "benzyl isoquinoline alkaloid metabolic process", "d": ["The chemical reactions and pathways involving benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:2000159", "l": "regulation of planar cell polarity pathway involved in heart morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019542", "l": "propionate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of propionate, the anion derived from propionic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904943", "l": "negative regulation of cardiac ventricle formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902836", "l": "positive regulation of proline import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of proline import into cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0021891", "l": "olfactory bulb interneuron development", "d": ["The process whose specific outcome is the progression of an interneuron residing in the olfactory bulb, from its initial commitment, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032901", "l": "positive regulation of neurotrophin production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of a neurotrophin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990969", "l": "modulation by host of viral RNA-binding transcription factor activity", "d": ["A process in which a host organism modulates the frequency, rate or extent of the activity of a viral RNA-binding transcription factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070811", "l": "glycerol-2-phosphate transmembrane transport", "d": ["The process in which glycerol-2-phosphate is transported across a membrane. Glycerol-2-phosphate is a phosphoric monoester of glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021718", "l": "superior olivary nucleus development", "d": ["The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140301", "l": "pollen-stigma interaction", "d": ["The interactions (or cell to cell communication) that occur between the pollen grain (male gametophyte) and the stigmatic tissues of the female sporophyte after the pollen reaches the stigmatic papillae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0043615", "l": "astrocyte cell migration", "d": ["The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0030979", "l": "alpha-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900327", "l": "regulation of mannotriose transport", "d": ["Any process that modulates the frequency, rate or extent of mannotriose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0099552", "l": "trans-synaptic signaling by lipid, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901216", "l": "positive regulation of neuron death", "d": ["Any process that activates or increases the frequency, rate or extent of neuron death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060753", "l": "regulation of mast cell chemotaxis", "d": ["Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035386", "l": "regulation of Roundabout signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the Roundabout signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.004905482618113", "identifiers": [{"i": "GO:0009636", "l": "response to toxic substance", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030721", "l": "spectrosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spectrosome, a germline specific spherical organelle that is the precursor to the fusome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090248", "l": "cell migration involved in somitogenic axis elongation", "d": ["Any process involved in the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0031103", "l": "axon regeneration", "d": ["The regrowth of axons following their loss or damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007496", "l": "anterior midgut development", "d": ["The process whose specific outcome is the progression of the anterior midgut over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071206", "l": "establishment of protein localization to juxtaparanode region of axon", "d": ["The directed movement of a protein to the juxtaparanode region of an axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0048528", "l": "post-embryonic root development", "d": ["The process whose specific outcome is the progression of the post-embryonic root over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0014745", "l": "negative regulation of muscle adaptation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902935", "l": "protein localization to septin ring", "d": ["A process in which a protein is transported to, or maintained in, a location within a septin ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035552", "l": "oxidative single-stranded DNA demethylation", "d": ["Removal of the methyl group from one or more nucleotides within a single-stranded DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110045", "l": "negative regulation of cell cycle switching, mitotic to meiotic cell cycle", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1902262", "l": "apoptotic process involved in blood vessel morphogenesis", "d": ["Any apoptotic process that is involved in blood vessel morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0030091", "l": "protein repair", "d": ["The process of restoring a protein to its original state after damage by such things as oxidation or spontaneous decomposition of residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034970", "l": "histone H3-R2 methylation", "d": ["The modification of histone H3 by addition of a methyl group to arginine at position 2 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902965", "l": "regulation of protein localization to early endosome", "d": ["Any process that modulates the frequency, rate or extent of protein localization to early endosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140878", "l": "griseofulvin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of griseofulvin, an important antifungal drug that has been in use for a long time for treating dermatophyte infections."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032468", "l": "Golgi calcium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901892", "l": "negative regulation of cell septum assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell septum assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0048525", "l": "negative regulation of viral process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034247", "l": "snoRNA splicing", "d": ["The process of removing sections of a primary snoRNA transcript to remove sequences not present in the mature form of the snoRNA and joining the remaining sections to form the mature form of the snoRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000894", "l": "cellotriose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a cellotriose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051759", "l": "sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation", "d": ["The directed movement of sister chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048397", "l": "positive regulation of intermediate mesodermal cell fate determination", "d": ["Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007157", "l": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "d": ["The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0034404", "l": "nucleobase-containing small molecule biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0060027", "l": "convergent extension involved in gastrulation", "d": ["The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.116918913335823", "identifiers": [{"i": "GO:0052553", "l": "modulation by symbiont of host immune response", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905830", "l": "positive regulation of prostaglandin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of prostaglandin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042374", "l": "phylloquinone metabolic process", "d": ["The chemical reactions and pathways involving phylloquinone, a quinone-derived compound synthesized by green plants. Phylloquinone has vitamin K activity and is known as vitamin K1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:1902319", "l": "DNA strand elongation involved in nuclear cell cycle DNA replication", "d": ["Any DNA strand elongation that is involved in nuclear cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0015888", "l": "thiamine transport", "d": ["The directed movement of thiamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904935", "l": "positive regulation of cell proliferation in midbrain", "d": ["Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900135", "l": "positive regulation of renin secretion into blood stream", "d": ["Any process that activates or increases the frequency, rate or extent of renin secretion into blood stream."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0048320", "l": "axial mesoderm formation", "d": ["The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901743", "l": "2-deoxystreptamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-deoxystreptamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035745", "l": "T-helper 2 cell cytokine production", "d": ["Any process that contributes to cytokine production by a T-helper 2 cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097097", "l": "nasal suture morphogenesis", "d": ["The process in which the nasal suture is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "48.982585856456822", "identifiers": [{"i": "GO:0048468", "l": "cell development", "d": ["The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033243", "l": "positive regulation of amine catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0080111", "l": "DNA demethylation", "d": ["The removal of a methyl group from one or more nucleotides within an DNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010809", "l": "negative regulation of synaptic vesicle priming", "d": ["Any process that decreases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021853", "l": "cerebral cortex GABAergic interneuron migration", "d": ["The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902273", "l": "negative regulation of (R)-carnitine transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of (R)-carnitine transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0071827", "l": "plasma lipoprotein particle organization", "d": ["A protein-lipid complex subunit organization process that results in the formation, disassembly, or alteration of a plasma lipoprotein particle. A plasma lipoprotein particle is a spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070952", "l": "regulation of neutrophil mediated killing of gram-positive bacterium", "d": ["Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-positive bacterium, the directed killing of a gram-positive bacterium by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905178", "l": "regulation of cardiac muscle tissue regeneration", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle tissue regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019744", "l": "hopanoid metabolic process", "d": ["The chemical reactions and pathways involving hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070365", "l": "hepatocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0005981", "l": "regulation of glycogen catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000438", "l": "negative regulation of monocyte extravasation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of monocyte extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042847", "l": "sorbose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043589", "l": "skin morphogenesis", "d": ["The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010909", "l": "positive regulation of heparan sulfate proteoglycan biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018262", "l": "isopeptide cross-linking", "d": ["The formation of a covalent cross-link between or within peptide chains, where either the amino group or the carboxyl group, or both, are not attached to the alpha carbon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097736", "l": "aerial mycelium formation", "d": ["The process by which hyphae grow in an upward or outward direction from the surface of the substrate; from there, propagative spores develop in or on characteristic structures that are distinctive of some fungal and bacterial species. The species that form an aerial mycelium develop conidiophores at the ends of the aerial hyphae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097302", "l": "lipoprotein biosynthetic process via diacylglyceryl transfer", "d": ["The chemical reactions and pathways by which diacylglyceryl transfer leads to formation of a water-soluble protein-lipid complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0009068", "l": "aspartate family amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.362525179576039", "identifiers": [{"i": "GO:0019730", "l": "antimicrobial humoral response", "d": ["An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904527", "l": "negative regulation of microtubule binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microtubule binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904698", "l": "negative regulation of acinar cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007130", "l": "synaptonemal complex assembly", "d": ["The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001106", "l": "regulation of Rho guanyl-nucleotide exchange factor activity", "d": ["Any process that modulates the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901758", "l": "butirosin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of butirosin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900495", "l": "negative regulation of butyryl-CoA biosynthetic process from acetyl-CoA", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010449", "l": "root meristem growth", "d": ["The increase in size or mass of a root meristem, a population of undifferentiated cells in a plant root which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into the growth of the root."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904463", "l": "ergosteryl 3-beta-D-glucoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ergosteryl 3-beta-D-glucoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990294", "l": "peptidyl-threonine trans-autophosphorylation", "d": ["The phosphorylation of a peptidyl-threonine to form peptidyl-O-phospho-L-threonine on an identical protein. For example, phosphorylation by the other kinase within a homodimer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046945", "l": "N-terminal peptidyl-alanine N-carbamoylation", "d": ["The carbamylation of the N-terminal alanine of proteins to form the derivative N-carbamoyl-L-alanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000522", "l": "positive regulation of immunological synapse formation", "d": ["Any process that activates or increases the frequency, rate or extent of immunological synapse formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0072203", "l": "cell proliferation involved in metanephros development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019464", "l": "glycine decarboxylation via glycine cleavage system", "d": ["The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0089704", "l": "L-glutamate transmembrane export from vacuole", "d": ["The directed movement of L-glutamate out of the vacuole, across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019708", "l": "peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine", "d": ["The synthesis of peptidyl-glycine cholest-5-en-3-beta-ol ester at the carboxy-terminus of autolytically cleaved proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0045433", "l": "male courtship behavior, veined wing generated song production", "d": ["The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0045168", "l": "cell-cell signaling involved in cell fate commitment", "d": ["Signaling at long or short range between cells that results in the commitment of a cell to a certain fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003246", "l": "embryonic cardiac muscle cell growth involved in heart morphogenesis", "d": ["The growth of a cardiac muscle cell during the embryonic period, that contributes to the shaping of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072161", "l": "mesenchymal cell differentiation involved in kidney development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0048819", "l": "regulation of hair follicle maturation", "d": ["Any process that modulates the frequency, rate or extent of hair follicle maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904188", "l": "negative regulation of transformation of host cell by virus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transformation of host cell by virus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010342", "l": "endosperm cellularization", "d": ["The separation of the multi-nucleate endosperm into individual cells. In many plant species, the endosperm that nurtures the embryo in the seed initially develops as a syncytium. This syncytial phase ends with simultaneous partitioning of the multi-nucleate cytoplasm into individual cells, a process referred to as cellularization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071252", "l": "cellular response to sulfur dioxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000605", "l": "positive regulation of secondary growth", "d": ["Any process that activates or increases the frequency, rate or extent of secondary growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0060760", "l": "positive regulation of response to cytokine stimulus", "d": ["Any process that increases the rate, frequency, or extent of a response to cytokine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905595", "l": "regulation of low-density lipoprotein particle receptor binding", "d": ["Any process that modulates the frequency, rate or extent of low-density lipoprotein particle receptor binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0055064", "l": "chloride ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of chloride ions within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0017121", "l": "plasma membrane phospholipid scrambling", "d": ["The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072191", "l": "ureter smooth muscle development", "d": ["The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042220", "l": "response to cocaine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019655", "l": "glycolytic fermentation to ethanol", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glucose; it is converted into ethanol and carbon dioxide (CO2), producing two molecules of ATP for each molecule of glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900198", "l": "positive regulation of penicillin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of penicillin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071976", "l": "cell gliding", "d": ["Cell motility that results in the smooth movement of a cell along a solid surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061433", "l": "cellular response to caloric restriction", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of caloric restriction, insufficient food energy intake."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1903332", "l": "regulation of protein folding", "d": ["Any process that modulates the frequency, rate or extent of protein folding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0036135", "l": "Schwann cell migration", "d": ["The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintainance and function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903315", "l": "negative regulation of nitrogen cycle metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nitrogen cycle metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0072111", "l": "cell proliferation involved in kidney development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032828", "l": "positive regulation of natural killer cell differentiation involved in immune response", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905570", "l": "positive regulation of ferrichrome biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ferrichrome biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043387", "l": "mycotoxin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a mycotoxin, any poisonous substance produced by a fungus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902780", "l": "response to nonane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048279", "l": "vesicle fusion with endoplasmic reticulum", "d": ["The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901714", "l": "positive regulation of urea catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of urea catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0060220", "l": "camera-type eye photoreceptor cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell in a camera-type eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002540", "l": "leukotriene production involved in inflammatory response", "d": ["The synthesis or release of any leukotriene following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0007202", "l": "activation of phospholipase C activity", "d": ["The initiation of the activity of the inactive enzyme phospolipase C as the result of The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030310", "l": "poly-N-acetyllactosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0160077", "l": "lipid droplet fusion", "d": ["The process by which a single lipid droplet is created from the fusion of two or more lipid droplets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070131", "l": "positive regulation of mitochondrial translation", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019102", "l": "male somatic sex determination", "d": ["The determination of sex and sexual phenotypes in a male organism's soma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900208", "l": "regulation of cardiolipin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cardiolipin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010797", "l": "regulation of multivesicular body size involved in endosome transport", "d": ["Any process that modulates the volume of a multivesicular body as part of the directed movement of substances from endosomes to lysosomes or vacuoles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010536", "l": "positive regulation of activation of Janus kinase activity", "d": ["Any process that increases the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904866", "l": "ventral tegmental area development", "d": ["The process whose specific outcome is the progression of a ventral tegmental area (VTA) over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.934711109505606", "identifiers": [{"i": "GO:0035249", "l": "synaptic transmission, glutamatergic", "d": ["The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902803", "l": "regulation of synaptic vesicle transport", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060213", "l": "positive regulation of nuclear-transcribed mRNA poly(A) tail shortening", "d": ["Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061504", "l": "cyclic threonylcarbamoyladenosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyclic threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070562", "l": "regulation of vitamin D receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of vitamin D receptor signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901325", "l": "response to antimycin A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021946", "l": "deep nuclear neuron cell migration", "d": ["The directed movement of a deep nuclear neuron from the ventricular zone to the deep hindbrain nuclei."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0050901", "l": "leukocyte tethering or rolling", "d": ["Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0097531", "l": "mast cell migration", "d": ["The movement of a mast cell within or between different tissues and organs of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "33.641327394574667", "identifiers": [{"i": "GO:0065007", "l": "biological regulation", "d": ["Any process that modulates a measurable attribute of any biological process, quality or function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902688", "l": "regulation of NAD metabolic process", "d": ["Any process that modulates the frequency, rate or extent of NAD metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016183", "l": "synaptic vesicle coating", "d": ["The formation of clathrin coated pits in the presynaptic membrane endocytic zone, triggered by the presence of high concentrations of synaptic vesicle components. This process leads to, but does not include budding of the membrane to form new vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050666", "l": "regulation of homocysteine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002619", "l": "regulation of non-professional antigen presenting cell antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.261443428098588", "identifiers": [{"i": "GO:0030010", "l": "establishment of cell polarity", "d": ["The specification and formation of anisotropic intracellular organization or cell growth patterns."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002399", "l": "MHC class II protein complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1902413", "l": "negative regulation of mitotic cytokinesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060525", "l": "prostate glandular acinus development", "d": ["The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902752", "l": "regulation of renal amino acid absorption", "d": ["Any process that modulates the frequency, rate or extent of renal amino acid absorption."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901319", "l": "positive regulation of trehalose catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of trehalose catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904506", "l": "negative regulation of telomere maintenance in response to DNA damage", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance in response to DNA damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002484", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902729", "l": "negative regulation of proteoglycan biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0042403", "l": "thyroid hormone metabolic process", "d": ["The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905163", "l": "negative regulation of phagosome maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phagosome maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048375", "l": "negative regulation of lateral mesodermal cell fate determination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904859", "l": "positive regulation of endothelial cell chemotaxis to vascular endothelial growth factor", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003432", "l": "cell growth involved in growth plate cartilage chondrocyte morphogenesis", "d": ["The growth of a growth plate cartilage chondrocyte, where growth contributes to the shaping of the chondrocyte over time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0097711", "l": "ciliary basal body-plasma membrane docking", "d": ["The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane."]}, {"i": "REACT:R-HSA-5620912.1", "d": []}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016200", "l": "synaptic target attraction", "d": ["The process in which a neuronal cell in a multicellular organism recognizes chemoattractant signals from, and grows towards, potential targets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070995", "l": "NADPH oxidation", "d": ["A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADPH, to the oxidized form, NADP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901092", "l": "positive regulation of protein tetramerization", "d": ["Any process that activates or increases the frequency, rate or extent of protein tetramerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902270", "l": "(R)-carnitine transmembrane transport", "d": ["The process in which (R)-carnitine is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0072182", "l": "regulation of nephron tubule epithelial cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019298", "l": "coenzyme B biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0042065", "l": "glial cell growth", "d": ["Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900032", "l": "regulation of trichome patterning", "d": ["Any process that modulates the frequency, rate or extent of trichome patterning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036155", "l": "acylglycerol acyl-chain remodeling", "d": ["Remodeling the acyl chains of an acylglycerol, through sequential deacylation and re-acylation reactions, to generate an acylglycerol containing different types of fatty acid acyl chains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903931", "l": "positive regulation of pyrimidine-containing compound salvage", "d": ["Any process that activates or increases the frequency, rate or extent of pyrimidine-containing compound salvage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007312", "l": "oocyte nucleus migration involved in oocyte dorsal/ventral axis specification", "d": ["The directed movement of the oocyte nucleus within the cell as part of the establishment and maintenance of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000420", "l": "negative regulation of eosinophil extravasation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046216", "l": "indole phytoalexin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of indole phytoalexins, any indole compound produced by plants as part of their defense response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010888", "l": "negative regulation of lipid storage", "d": ["Any process that decreases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051080", "l": "meiosis II nuclear membrane disassembly", "d": ["The controlled breakdown of the nuclear membranes during the second division of meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905694", "l": "negative regulation of phosphatidic acid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090117", "l": "endosome to lysosome transport of low-density lipoprotein particle", "d": ["The directed movement of low-density lipoprotein particle from endosomes to lysosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048453", "l": "sepal formation", "d": ["The process that gives rise to the sepal. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061868", "l": "hepatic stellate cell migration", "d": ["The orderly movement of a hepatic stellate cell from one site to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0009699", "l": "phenylpropanoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aromatic derivatives of trans-cinnamic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.509418971541265", "identifiers": [{"i": "GO:0071554", "l": "cell wall organization or biogenesis", "d": ["A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902317", "l": "nuclear DNA replication termination", "d": ["Any DNA replication termination that is involved in nuclear cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902728", "l": "positive regulation of growth factor dependent skeletal muscle satellite cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0021785", "l": "branchiomotor neuron axon guidance", "d": ["The process in which a branchiomotor neuron growth cone is directed to a specific target site. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0071867", "l": "response to monoamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000543", "l": "positive regulation of gastrulation", "d": ["Any process that activates or increases the frequency, rate or extent of gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002044", "l": "blood vessel endothelial cell migration involved in intussusceptive angiogenesis", "d": ["The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels during intussusceptive angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009050", "l": "glycopeptide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycopeptides, a compound in which carbohydrate is covalently attached to an oligopeptide composed of residues of L and/or D-amino acids. The term usually denotes a product of proteolytic degradation of a glycoprotein but includes glycated peptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0080182", "l": "histone H3-K4 trimethylation", "d": ["The modification of histone H3 by addition of three methyl groups to lysine at position 4 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030809", "l": "negative regulation of nucleotide biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072313", "l": "metanephric glomerular epithelial cell development", "d": ["The process whose specific outcome is the progression of a metanephric glomerular epithelial cell over time, from its formation to the mature structure. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001285", "l": "negative regulation of BMP secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of BMP secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901129", "l": "gentamycin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of gentamycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902131", "l": "(+)-lariciresinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (+)-lariciresinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901500", "l": "response to p-xylene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a p-xylene stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0006498", "l": "N-terminal protein lipidation", "d": ["The covalent attachment of a lipid group to the amino terminus of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.946808109399541", "identifiers": [{"i": "GO:0007417", "l": "central nervous system development", "d": ["The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031541", "l": "negative regulation of anthocyanin biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034345", "l": "negative regulation of type III interferon production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044572", "l": "[4Fe-4S] cluster assembly", "d": ["The incorporation of four iron atoms and four sulfur atoms into an iron-sulfur cluster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903949", "l": "positive regulation of atrial cardiac muscle cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of atrial cardiac muscle cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045938", "l": "positive regulation of circadian sleep/wake cycle, sleep", "d": ["Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048378", "l": "regulation of lateral mesodermal cell fate specification", "d": ["Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044387", "l": "negative regulation of protein kinase activity by regulation of protein phosphorylation", "d": ["The stopping, prevention, or reduction in frequency, rate or extent of protein kinase activity as a result of regulating the phosphorylation status of that protein kinase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035832", "l": "berbamunine metabolic process", "d": ["The chemical reactions and pathways involving berbamunine, an isoquinoline alkaloid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046497", "l": "nicotinate nucleotide metabolic process", "d": ["The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid, or niacin)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051585", "l": "negative regulation of dopamine uptake involved in synaptic transmission", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of dopamine into a presynaptic neuron or glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0044344", "l": "cellular response to fibroblast growth factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097528", "l": "execution phase of necroptosis", "d": ["A stage of the necroptotic process that starts after a necroptotic signal has been relayed to the execution machinery. Key steps of the execution phase are swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. The execution phase ends when the cell has died."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0006024", "l": "glycosaminoglycan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007454", "l": "labial disc morphogenesis", "d": ["The process in which the anatomical structures derived from the labial disc are generated and organized. This includes the transformation of a labial imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including parts of the proboscis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904330", "l": "positive regulation of myofibroblast contraction", "d": ["Any process that activates or increases the frequency, rate or extent of myofibroblast contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021721", "l": "superior olivary nucleus structural organization", "d": ["The process that contributes to the act of creating the structural organization of the superior olivary nucleus structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106146", "l": "sideretin biosynthesis", "d": ["The chemical reactions and pathways resulting in the formation of sideretin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.675373588411375", "identifiers": [{"i": "GO:1901661", "l": "quinone metabolic process", "d": ["The chemical reactions and pathways involving quinone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048313", "l": "Golgi inheritance", "d": ["The partitioning of Golgi apparatus between daughter cells at cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "45.072489031630809", "identifiers": [{"i": "GO:0007610", "l": "behavior", "d": ["The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000409", "l": "positive regulation of T cell extravasation", "d": ["Any process that activates or increases the frequency, rate or extent of T cell extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000132", "l": "establishment of mitotic spindle orientation", "d": ["A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006585", "l": "dopamine biosynthetic process from tyrosine", "d": ["The chemical reactions and pathways resulting in the formation of dopamine (3,4-dihydroxyphenylethylamine) from L-tyrosine, via the metabolic precursor 3,4-dihydroxy-L-phenylalanine (L-dopa). Dopamine is a catecholamine neurotransmitter and a metabolic precursor of norepinephrine and epinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0010517", "l": "regulation of phospholipase activity", "d": ["Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0098728", "l": "germline stem cell asymmetric division", "d": ["The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071726", "l": "cellular response to diacyl bacterial lipopeptide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071230", "l": "cellular response to amino acid stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039710", "l": "cytoplasmic icosahedral capsid assembly", "d": ["The assembly of an icosahedral viral capsid in the cytoplasm. Often occurs by assembling around the viral genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900132", "l": "positive regulation of lipid binding", "d": ["Any process that activates or increases the frequency, rate or extent of lipid binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032007", "l": "negative regulation of TOR signaling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061633", "l": "transport-coupled glycolytic process through glucose-6-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, in which the glucose is converted to glucose-6-phosphate intermediate coupled to transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1990139", "l": "protein localization to nuclear periphery", "d": ["A process in which a protein is transported to, or maintained in, a location within the nuclear periphery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0061438", "l": "renal system vasculature morphogenesis", "d": ["The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903015", "l": "regulation of exo-alpha-sialidase activity", "d": ["Any process that modulates the frequency, rate or extent of exo-alpha-sialidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0055008", "l": "cardiac muscle tissue morphogenesis", "d": ["The process in which the anatomical structures of cardiac muscle tissue are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120315", "l": "positive regulation of oocyte karyosome formation", "d": ["Any process that activates or increases the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2000024", "l": "regulation of leaf development", "d": ["Any process that modulates the frequency, rate or extent of leaf development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0005985", "l": "sucrose metabolic process", "d": ["The chemical reactions and pathways involving sucrose, the disaccharide fructofuranosyl-glucopyranoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140754", "l": "reorganization of cellular membranes to establish viral sites of replication", "d": ["A process in intracellular membranes are reorganized by viral proteins that perturb membrane integrity and can cause an extensive rearrangement of cellular membranes, forming membranous webs, which are thought to be the site of replication or certain viruses, for example the HPV virus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0099625", "l": "ventricular cardiac muscle cell membrane repolarization", "d": ["The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043378", "l": "positive regulation of CD8-positive, alpha-beta T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140609", "l": "phycocyanobilin biosynthetic process", "d": ["The chemical reactions or pathway resulting in the formation of phycocyanobilin, which involves the oxidative cleavage of heme by a heme oxygenase (HO) to form biliverdin IX alpha. Biliverdin IX alpha is subsequently converted to phycocyanobilin by a ferredoxin-dependent oxidoreductase (PCYA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098544", "l": "maintenance of protein complex location", "d": ["Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000140", "l": "negative regulation of octopamine signaling pathway involved in response to food", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway involved in response to food."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044559", "l": "envenomation resulting in modulation of voltage-gated potassium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated potassium channel in the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0042724", "l": "thiamine-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), and related compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021802", "l": "somal translocation", "d": ["The radial migration of cells from the ventricular zone that is independent of radial glial cells. Cells extend processes that terminate at the pial surface and follow the processes as they migrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.773387538292397", "identifiers": [{"i": "GO:0001906", "l": "cell killing", "d": ["Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075329", "l": "regulation of arbuscule formation for nutrient acquisition from host", "d": ["Any process that modulates the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.191563080215587", "identifiers": [{"i": "GO:0043171", "l": "peptide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2001104", "l": "heptasaccharide transport", "d": ["The directed movement of a heptasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046376", "l": "GDP-alpha-D-mannosylchitobiosyldiphosphodolichol metabolic process", "d": ["The chemical reactions and pathways involving GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098006", "l": "viral DNA genome packaging, headful", "d": ["The encapsulation of the viral genome within the capsid where DNA is packaged into the capsid until the capsid is full."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0002584", "l": "negative regulation of antigen processing and presentation of peptide antigen", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045699", "l": "positive regulation of synergid differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of synergid cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044258", "l": "intestinal lipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0007008", "l": "outer mitochondrial membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial outer membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043323", "l": "positive regulation of natural killer cell degranulation", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer cell degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905723", "l": "negative regulation of trypanothione biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of trypanothione biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010164", "l": "response to cesium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035880", "l": "embryonic nail plate morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of a nail plate are generated and organized. The nail plate is the hard and translucent portion of the nail, composed of keratin, and serves to protect the tips of digits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090290", "l": "positive regulation of osteoclast proliferation", "d": ["Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052078", "l": "disruption of host pathogen-associated molecular pattern receptor signaling pathway", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of a host PMAP signaling pathwaay, initiated by a ligand binding of a pattern recognition receptor (PRR) to activate a plant innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0080170", "l": "hydrogen peroxide transmembrane transport", "d": ["The process in which hydrogen peroxide is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035118", "l": "embryonic pectoral fin morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048108", "l": "peptide cross-linking via 4-amino-3-isothiazolidinone", "d": ["The formation of 4-amino-3-isothiazolinone cross-links by the formation of a sulfenylamide bond between cysteine or cysteine sulfenic acid, and the alpha-amido of the following residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071485", "l": "cellular response to absence of light", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0051673", "l": "perturbation of plasma membrane integrity in another organism", "d": ["The disruption of the cell membrane of another organism, leading to damage or temporary subversion of the membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990001", "l": "inhibition of cysteine-type endopeptidase activity involved in apoptotic process", "d": ["Any process that prevents the activation of an inactive cysteine-type endopeptidase involved in an apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903845", "l": "negative regulation of cellular response to transforming growth factor beta stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to transforming growth factor beta stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902383", "l": "11-oxo-beta-amyrin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 11-oxo-beta-amyrin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902833", "l": "positive regulation of cell proliferation in dorsal spinal cord", "d": ["Any process that activates or increases the frequency, rate or extent of cell proliferation in dorsal spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904093", "l": "negative regulation of autophagic cell death", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of autophagic cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0007413", "l": "axonal fasciculation", "d": ["The collection of axons into a bundle of rods, known as a fascicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0034453", "l": "microtubule anchoring", "d": ["Any process in which a microtubule is maintained in a specific location in a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990818", "l": "L-arginine transmembrane export from vacuole", "d": ["The directed movement of L-arginine out of the vacuole, across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046842", "l": "trisporic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of trisporic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106225", "l": "peptidyl-lysine 2-hydroxyisobutyrylation", "d": ["The 2-hydroxyisobutyrylation of a lysine residue in a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905322", "l": "positive regulation of mesenchymal stem cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061581", "l": "corneal epithelial cell migration", "d": ["The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090625", "l": "siRNA-mediated gene silencing by mRNA destabilization", "d": ["An siRNA-mediated post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), an siRNA will typically direct cleavage by base pairing with perfect or near-perfect complementarity to the target mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061205", "l": "paramesonephric duct development", "d": ["The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903563", "l": "microtubule bundle formation involved in horsetail-astral microtubule organization", "d": ["Any microtubule bundle formation that is involved in horsetail-astral microtubule organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002448", "l": "mast cell mediated immunity", "d": ["Any process involved in the carrying out of an immune response by a mast cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0098727", "l": "maintenance of cell number", "d": ["Any process by which the numbers of cells of a particular type or in a tissue are maintained."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0051953", "l": "negative regulation of amine transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106113", "l": "positive regulation of mitotic cohesin ssDNA (lagging strand) loading", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904972", "l": "negative regulation of viral translation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of viral translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900762", "l": "averantin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of averantin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905636", "l": "positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0003085", "l": "negative regulation of systemic arterial blood pressure", "d": ["The process that reduces the force with which blood travels through the systemic arterial circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002354", "l": "central B cell negative selection", "d": ["Any process leading to negative selection of B cells in the bone marrow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000324", "l": "positive regulation of glucocorticoid receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of glucocorticoid receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098863", "l": "nuclear migration by microtubule mediated pushing forces", "d": ["The directed movement of the nucleus by pushing forces exerted by polymerization of backward-extending microtubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051337", "l": "amitosis", "d": ["Nuclear division that occurs by simple constriction of the nucleus without chromosome condensation or spindle formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905213", "l": "negative regulation of mitotic chromosome condensation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009780", "l": "photosynthetic NADP+ reduction", "d": ["An NADPH regeneration process that contributes to the light reactions of photosynthesis. The light reactions of photosynthesis use energy from photons to generate high-energy electrons. These electrons are used directly to reduce NADP+ to NADPH. NADPH is a relatively stable molecule and can pass on its hydrogen atom to other molecules in chemical reactions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097171", "l": "ADP-L-glycero-beta-D-manno-heptose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901768", "l": "carbapenem catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carbapenem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905630", "l": "response to glyceraldehyde", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035920", "l": "negative regulation of high voltage-gated calcium channel activity in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a high voltage-gated calcium channel in another organism. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051134", "l": "negative regulation of NK T cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031064", "l": "negative regulation of histone deacetylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the removal of acetyl groups from histones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045993", "l": "negative regulation of translational initiation by iron", "d": ["Any process involving iron that stops, prevents or reduces the rate of translational initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015910", "l": "long-chain fatty acid import into peroxisome", "d": ["The directed movement of a long-chain fatty acid into a peroxisome. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033242", "l": "negative regulation of amine catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.414603710654305", "identifiers": [{"i": "GO:2000147", "l": "positive regulation of cell motility", "d": ["Any process that activates or increases the frequency, rate or extent of cell motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000726", "l": "negative regulation of cardiac muscle cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905917", "l": "positive regulation of cell differentiation involved in phenotypic switching", "d": ["Any process that activates or increases the frequency, rate or extent of cell differentiation involved in phenotypic switching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048343", "l": "paraxial mesodermal cell fate commitment", "d": ["The process in which a cell becomes committed to become a paraxial mesoderm cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0016079", "l": "synaptic vesicle exocytosis", "d": ["Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000872", "l": "positive regulation of progesterone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of progesterone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051686", "l": "establishment of ER localization", "d": ["The directed movement of the endoplasmic reticulum to a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010868", "l": "negative regulation of triglyceride biosynthetic process", "d": ["Any process that decreases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021672", "l": "rhombomere 7 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 7. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905187", "l": "negative regulation of metaphase/anaphase transition of meiosis I", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032614", "l": "interleukin-11 production", "d": ["The appearance of interleukin-11 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140408", "l": "regulation of mRNA alternative polyadenylation", "d": ["Any process that modulates the frequency, rate or extent of mRNA alternative polyadenylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901771", "l": "daunorubicin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of daunorubicin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032460", "l": "negative regulation of protein oligomerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.892466024748572", "identifiers": [{"i": "GO:0006081", "l": "cellular aldehyde metabolic process", "d": ["The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090206", "l": "negative regulation of cholesterol metabolic process", "d": ["Any process that decreases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050675", "l": "regulation of urothelial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of urothelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903333", "l": "negative regulation of protein folding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein folding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021717", "l": "inferior olivary nucleus maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032834", "l": "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response", "d": ["Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070922", "l": "RISC complex assembly", "d": ["The process in which a single-stranded small RNA is incorporated within the RNA-initiated silencing complex (RISC). The assembly includes the maturation of the small RNA, the stabilization of the complex by accessory proteins of the RISC complex, duplex separation and the release of the second strand, forming a base-pairing completent complex that mediates gene silencing by small RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.542510287032449", "identifiers": [{"i": "GO:0012501", "l": "programmed cell death", "d": ["A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021705", "l": "locus ceruleus formation", "d": ["The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060449", "l": "bud elongation involved in lung branching", "d": ["The process in which a bud in the lung grows out from the point where it is formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1901623", "l": "regulation of lymphocyte chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0140279", "l": "regulation of mitotic division septum assembly", "d": ["Any process that modulates the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035751", "l": "regulation of lysosomal lumen pH", "d": ["Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0009657", "l": "plastid organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plastid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0051209", "l": "release of sequestered calcium ion into cytosol", "d": ["The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071835", "l": "mating pheromone secretion involved in regulation of conjugation with cellular fusion", "d": ["The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that regulates the union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905263", "l": "positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination", "d": ["Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071228", "l": "cellular response to tumor cell", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0043084", "l": "penile erection", "d": ["The hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016260", "l": "selenocysteine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of selenocysteine, an essential component of glutathione peroxidase and some other proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075138", "l": "response to host oxygen tension environment", "d": ["Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting oxygen tension in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903520", "l": "negative regulation of mammary gland involution", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mammary gland involution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048779", "l": "negative regulation of erythrophore differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of erythrophore differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140204", "l": "pyridoxal import across plasma membrane", "d": ["The directed movement of pyridoxal from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903548", "l": "negative regulation of growth hormone activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of growth hormone activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903391", "l": "regulation of adherens junction organization", "d": ["Any process that modulates the frequency, rate or extent of adherens junction organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051819", "l": "induction by symbiont of tumor or growth in host", "d": ["The process in which a symbiont causes the formation of a mass of cells in a host organism. While these growths are often called nodules, they are not formed as nitrogen-fixing structures, but rather to provide an environment for the symbiont to grow. In this sense they are parasitic structures rather than mutualistic."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0046121", "l": "deoxyribonucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010343", "l": "singlet oxygen-mediated programmed cell death", "d": ["Programmed cell death induced by singlet oxygen. Programmed cell death is the cell death resulting from activation of endogenous cellular processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000286", "l": "receptor internalization involved in canonical Wnt signaling pathway", "d": ["A receptor internalization process that contributes to canonical Wnt signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902257", "l": "negative regulation of apoptotic process involved in outflow tract morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0000731", "l": "DNA synthesis involved in DNA repair", "d": ["Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous intact duplex as the template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "51.976759198207681", "identifiers": [{"i": "GO:0010033", "l": "response to organic substance", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0006363", "l": "termination of RNA polymerase I transcription", "d": ["A transcription termination process that completes the production of a ribosomal RNA transcript. RNAP I termination requires binding of a terminator protein to specific sequences downstream of the transcription unit."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060364", "l": "frontal suture morphogenesis", "d": ["The process in which the frontal suture is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035713", "l": "response to nitrogen dioxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097095", "l": "frontonasal suture morphogenesis", "d": ["The process in which the frontonasal suture, between frontal and nasal bones, is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071474", "l": "cellular hyperosmotic response", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046009", "l": "positive regulation of female receptivity, post-mating", "d": ["Any process that increases the receptiveness of a female to male advances subsequent to mating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046318", "l": "negative regulation of glucosylceramide biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052780", "l": "chitobiose metabolic process", "d": ["The chemical reactions and pathways involving chitobioses, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0032435", "l": "negative regulation of proteasomal ubiquitin-dependent protein catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110124", "l": "positive regulation of myotube cell migration", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902900", "l": "gut granule assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a gut granule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.780700721499244", "identifiers": [{"i": "GO:0003009", "l": "skeletal muscle contraction", "d": ["A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048527", "l": "lateral root development", "d": ["The process whose specific outcome is the progression of the lateral root over time, from its formation to the mature structure. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036241", "l": "glutamate catabolic process to 4-hydroxybutyrate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate into 4-hydroxybutyrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900967", "l": "positive regulation of methanophenazine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of methanophenazine metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0080129", "l": "proteasome core complex assembly", "d": ["The aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002239", "l": "response to oomycetes", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an oomycetes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060704", "l": "acinar cell differentiation involved in salivary gland development", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014813", "l": "skeletal muscle satellite cell commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a satellite cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002383", "l": "immune response in brain or nervous system", "d": ["An immune response taking place in the brain or nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035278", "l": "miRNA-mediated gene silencing by inhibition of translation", "d": ["An RNA interference pathway in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.622337805354121", "identifiers": [{"i": "GO:0046890", "l": "regulation of lipid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1901380", "l": "negative regulation of potassium ion transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032347", "l": "regulation of aldosterone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048755", "l": "branching morphogenesis of a nerve", "d": ["The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0046323", "l": "glucose import", "d": ["The directed movement of the hexose monosaccharide glucose into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0022606", "l": "establishment of proximal/distal cell polarity", "d": ["The specification and formation of the polarity of a cell along its proximal/distal axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0071625", "l": "vocalization behavior", "d": ["The behavior in which an organism produces sounds by a mechanism involving its respiratory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0042269", "l": "regulation of natural killer cell mediated cytotoxicity", "d": ["Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007381", "l": "specification of segmental identity, labial segment", "d": ["The specification of the characteristic structures of the labial segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031539", "l": "positive regulation of anthocyanin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways involving anthocyanins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.381173084437549", "identifiers": [{"i": "GO:0046883", "l": "regulation of hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0043574", "l": "peroxisomal transport", "d": ["Transport of substances into, out of or within a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903472", "l": "negative regulation of mitotic actomyosin contractile ring contraction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060035", "l": "notochord cell development", "d": ["The process whose specific outcome is the progression of a notochord cell over time, from its formation to its mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048174", "l": "negative regulation of short-term neuronal synaptic plasticity", "d": ["A process that decreases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.651716354923636", "identifiers": [{"i": "GO:0036075", "l": "replacement ossification", "d": ["Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0140448", "l": "signaling receptor ligand precursor processing", "d": ["The cleavage of a peptide bond in a precursor form of a signaling receptor ligand, resulting in the mature (active) form of the ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903866", "l": "palisade mesophyll development", "d": ["The process whose specific outcome is the progression of a palisade mesophyll over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0060209", "l": "estrus", "d": ["The estrous cycle phase in which a female is sexually receptive."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043421", "l": "anthranilate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of anthranilate (2-aminobenzoate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0120110", "l": "interphase mitotic telomere clustering", "d": ["The process whereby the mitotic telomeres are gathered together during, or prior to, attachment to the nuclear envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018903", "l": "1,3-dichloropropene metabolic process", "d": ["The chemical reactions and pathways involving members of the 1,3-dichloropropene family, which includes cis- and trans-1,3-dichloropropene. The 1,3-dichloropropenes are chlorinated hydrocarbons and the major active ingredients of commercial products for control of plant-parasitic nematodes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048725", "l": "cibarial fish-trap bristle development", "d": ["The process whose specific outcome is the progression of the cibarial fish-trap bristle over time, from its formation to the mature structure. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0052081", "l": "modulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway", "d": ["Any process in which an organism modulates the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010573", "l": "vascular endothelial growth factor production", "d": ["The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090126", "l": "protein-containing complex assembly involved in synapse maturation", "d": ["The aggregation, arrangement and bonding together of a set of components to form a protein complex that contributes to synapse maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030329", "l": "prenylcysteine metabolic process", "d": ["The chemical reactions and pathways involving prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010021", "l": "amylopectin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amylopectin, the (1->4) linked alpha glucose units with alpha-(1->6) linkages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007481", "l": "haltere disc morphogenesis", "d": ["The process in which the anatomical structures derived from the haltere disc are generated and organized. This includes the transformation of a haltere imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042407", "l": "cristae formation", "d": ["The assembly of cristae, the inwards folds of the inner mitochondrial membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000710", "l": "negative regulation of maintenance of meiotic sister chromatid cohesion, centromeric", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060014", "l": "granulosa cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039564", "l": "disruption by virus of host JAK-STAT cascade via inhibition of STAT2 activity", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT2 (signal transducer and activator of transcription 2)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902233", "l": "negative regulation of positive thymic T cell selection", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of positive thymic T cell selection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071647", "l": "negative regulation of macrophage inflammatory protein-1 gamma production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900017", "l": "positive regulation of cytokine production involved in inflammatory response", "d": ["Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901128", "l": "gentamycin metabolic process", "d": ["The chemical reactions and pathways involving gentamycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042952", "l": "beta-ketoadipate pathway", "d": ["A pathway of aromatic compound degradation by ortho-cleavage; one branch converts protocatechuate, derived from phenolic compounds, to beta-ketoadipate, and the other branch converts catechol, generated from various aromatic hydrocarbons, amino aromatics, and lignin monomers, also to beta-ketoadipate. Two additional steps accomplish the conversion of beta-ketoadipate to tricarboxylic acid cycle intermediates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033248", "l": "negative regulation of penicillin catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071308", "l": "cellular response to menaquinone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900033", "l": "negative regulation of trichome patterning", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of trichome patterning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045035", "l": "sensory organ precursor cell division", "d": ["The series of four asymmetric divisions undergone by the sensory organ precursor cells to generate cells that have distinct cell fates. For example, in the external sensory organ, the precursor cells give rise to one multidendritic neuron and four additional cells (the socket, shaft, sheath cells and the external sense neuron)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903415", "l": "flavonoid transport from endoplasmic reticulum to plant-type vacuole", "d": ["The directed movement of flavonoid from endoplasmic reticulum to plant-type vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032130", "l": "medial membrane band assembly", "d": ["The assembly of a sterol-rich region of the plasma membrane at the cell surface overlying the contractile ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006867", "l": "asparagine transport", "d": ["The directed movement of asparagine, alpha-aminosuccinamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "45.541196816171663", "identifiers": [{"i": "GO:0048519", "l": "negative regulation of biological process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003421", "l": "growth plate cartilage axis specification", "d": ["The establishment, maintenance and elaboration of the columnar cartilage along the axis of a long bone that contributes to bone growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035490", "l": "regulation of leukotriene production involved in inflammatory response", "d": ["Any process that modulates the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032788", "l": "saturated monocarboxylic acid metabolic process", "d": ["The chemical reactions and pathways involving saturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and fully saturated C-C bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0052041", "l": "suppression by symbiont of host programmed cell death", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071836", "l": "nectar secretion", "d": ["The controlled release of a nectar by a cell or a tissue. Nectar is a fluid secreted by many angiosperms to promote pollination by providing a reward to pollinators. Nectar may also deter certain organisms from visiting or play other biological roles. Nectar is a complex solution that may include the following types of compounds: sugars, amino acids, organic acids, alkaloids, flavonoids, glycosides, vitamins, phenolics, metal ions, oils, free fatty acids, and proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904612", "l": "response to 2,3,7,8-tetrachlorodibenzodioxine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060518", "l": "cell migration involved in prostatic bud elongation", "d": ["The orderly movement of epithelial cells from one site to another contributing to the elongation of the primary prostatic bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006264", "l": "mitochondrial DNA replication", "d": ["The process in which new strands of DNA are synthesized in the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0034341", "l": "response to type II interferon", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905911", "l": "positive regulation of dauer entry", "d": ["Any process that activates or increases the frequency, rate or extent of dauer entry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905816", "l": "negative regulation of dorsal/ventral axon guidance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dorsal/ventral axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0000291", "l": "nuclear-transcribed mRNA catabolic process, exonucleolytic", "d": ["The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap or the 3'-poly(A) tail."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018897", "l": "dibenzothiophene desulfurization", "d": ["The removal of the sulfur atom from dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0018216", "l": "peptidyl-arginine methylation", "d": ["The addition of a methyl group to an arginine residue in a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000918", "l": "division septum site selection", "d": ["The process of marking the site where a division septum will form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904770", "l": "intramembranous bone morphogenesis", "d": ["The developmental process by which an intramembranous bone is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033383", "l": "geranyl diphosphate metabolic process", "d": ["The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019661", "l": "glucose catabolic process to lactate via pyruvate", "d": ["The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, via canonical glycolysis, yielding energy in the form of adenosine triphosphate (ATP)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901785", "l": "p-cresol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of p-cresol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019352", "l": "protoporphyrinogen IX biosynthetic process from glycine", "d": ["The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1990608", "l": "mitotic spindle pole body localization", "d": ["A process in which a mitotic spindle pole body is transported to, or maintained in, a specific cellular location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.790184063220053", "identifiers": [{"i": "GO:0040008", "l": "regulation of growth", "d": ["Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.594043123901756", "identifiers": [{"i": "GO:0046632", "l": "alpha-beta T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000207", "l": "negative regulation of ribosomal small subunit export from nucleus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal small subunit export from nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030325", "l": "adrenal gland development", "d": ["The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042372", "l": "phylloquinone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006227", "l": "dUDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dUDP, deoxyuridine diphosphate (2'-deoxy-5'-uridylyl phosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035137", "l": "hindlimb morphogenesis", "d": ["The process in which the anatomical structures of the hindlimb are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002554", "l": "serotonin secretion by platelet", "d": ["The regulated release of serotonin by a platelet or group of platelets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0039654", "l": "fusion of virus membrane with host endosome membrane", "d": ["Fusion of a virus membrane with a host endosome membrane. Occurs after internalization of the virus through the endosomal pathway, and results in release of the virus contents into the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900842", "l": "positive regulation of helvolic acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of helvolic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903447", "l": "geraniol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of geraniol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.124646994401843", "identifiers": [{"i": "GO:0001764", "l": "neuron migration", "d": ["The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046090", "l": "deoxyadenosine metabolic process", "d": ["The chemical reactions and pathways involving deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006586", "l": "indolalkylamine metabolic process", "d": ["The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "30.659656384310537", "identifiers": [{"i": "GO:0009791", "l": "post-embryonic development", "d": ["The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000012", "l": "regulation of auxin polar transport", "d": ["Any process that modulates the frequency, rate or extent of auxin polar transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000652", "l": "regulation of secondary cell wall biogenesis", "d": ["Any process that modulates the frequency, rate or extent of secondary cell wall biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0042176", "l": "regulation of protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014028", "l": "notochord formation", "d": ["The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036074", "l": "metaplastic ossification", "d": ["Direct ossification in which bone formation occurs as result of the direct transformation of non-bone cells into bone cells without cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0006692", "l": "prostanoid metabolic process", "d": ["The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075530", "l": "establishment of latency as a linear episome", "d": ["A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as linear structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060316", "l": "positive regulation of ryanodine-sensitive calcium-release channel activity", "d": ["Any process that increases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.712091546727706", "identifiers": [{"i": "GO:0097305", "l": "response to alcohol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001810", "l": "regulation of type I hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of type I hypersensitivity, a type of inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110077", "l": "vesicle-mediated intercellular transport", "d": ["A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0002786", "l": "regulation of antibacterial peptide production", "d": ["Any process that modulates the frequency, rate, or extent of antibacterial peptide production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120068", "l": "regulation of stomach fundus smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of any stomach fundus smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036067", "l": "light-dependent chlorophyll biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the presence of light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0039657", "l": "suppression by virus of host gene expression", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of gene expression in the host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099574", "l": "regulation of protein catabolic process at synapse, modulating synaptic transmission", "d": ["Any process that modulates synaptic transmission by regulating protein degradation at the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904592", "l": "positive regulation of protein refolding", "d": ["Any process that activates or increases the frequency, rate or extent of protein refolding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:1903959", "l": "regulation of monoatomic anion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of anion transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901187", "l": "regulation of ephrin receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of ephrin receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019607", "l": "phenylethylamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071336", "l": "regulation of hair follicle cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of hair follicle cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904697", "l": "regulation of acinar cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of acinar cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006001", "l": "fructose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fructose, the ketohexose arabino-2-hexulose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.200727389249643", "identifiers": [{"i": "GO:0002682", "l": "regulation of immune system process", "d": ["Any process that modulates the frequency, rate, or extent of an immune system process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.473342453951815", "identifiers": [{"i": "GO:0048477", "l": "oogenesis", "d": ["The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120190", "l": "negative regulation of bile acid secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044734", "l": "envenomation resulting in positive regulation of acid-sensing ion channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant positive regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032836", "l": "glomerular basement membrane development", "d": ["The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060697", "l": "positive regulation of phospholipid catabolic process", "d": ["Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900760", "l": "negative regulation of sterigmatocystin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sterigmatocystin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002337", "l": "B-1a B cell differentiation", "d": ["The process in which B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0008365", "l": "adult chitin-based cuticle development", "d": ["Synthesis and deposition of the chitin-based cuticle of adults following the apolysis of the pupal cuticle. The adult insect cuticle contains cuticullin, a protein epicuticle and a lamellate procuticle. An example of this process is adult chitin-based cuticle development in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021574", "l": "rhombomere 8 development", "d": ["The process whose specific outcome is the progression of rhombomere 8 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046520", "l": "sphingoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:0006704", "l": "glucocorticoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006237", "l": "deoxycytidine salvage", "d": ["Any process that generates deoxycytidine, 2-deoxyribosylcytosine, from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901045", "l": "negative regulation of egg-laying behavior", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of oviposition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048057", "l": "R3/R4 development", "d": ["The process whose specific outcome is the progression of the R3 and R4 pair of photoreceptors in the eye over time, from their formation to the mature structures. R3 and R4 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097477", "l": "lateral motor column neuron migration", "d": ["The orderly movement of a lateral motor column neuron from one site to another. A lateral motor column neuron is a motor neuron that is generated only on limb levels and send axons into the limb mesenchyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0048881", "l": "mechanosensory lateral line system development", "d": ["The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0002580", "l": "regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032708", "l": "negative regulation of interleukin-24 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-24 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002201", "l": "somatic diversification of DSCAM-based immune receptors", "d": ["The somatic process that results in the generation of sequence diversity of the DSCAM-based immune receptors of insects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990076", "l": "cell wall polysaccharide catabolic process involved in abscission", "d": ["Any cell wall polysaccharide catabolic process that is involved in abscission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.086235947127733", "identifiers": [{"i": "GO:0071482", "l": "cellular response to light stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0060285", "l": "cilium-dependent cell motility", "d": ["Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0086071", "l": "atrial cardiac muscle cell-AV node cell adhesion involved in cell communication", "d": ["The attachment of an atrial cardiomyocyte to an AV node cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003380", "l": "establishment or maintenance of cytoskeleton polarity involved in gastrulation", "d": ["Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035504", "l": "regulation of myosin light chain kinase activity", "d": ["Any process that modulates the frequency, rate or extent of myosin light chain kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901672", "l": "positive regulation of systemic acquired resistance", "d": ["Any process that activates or increases the frequency, rate or extent of systemic acquired resistance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007220", "l": "Notch receptor processing", "d": ["The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.444551060876734", "identifiers": [{"i": "GO:0061138", "l": "morphogenesis of a branching epithelium", "d": ["The process in which the anatomical structures of a branched epithelium are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106014", "l": "regulation of inflammatory response to wounding", "d": ["Any process that modulates the frequency, rate or extent of the inflammatory response to wounding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021719", "l": "superior olivary nucleus morphogenesis", "d": ["The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0007625", "l": "grooming behavior", "d": ["The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0050932", "l": "regulation of pigment cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of pigmented cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060598", "l": "dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis", "d": ["The process in which the terminal end of a mammary duct bifurcates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048109", "l": "peptide cross-linking via 2-amino-3-isothiazolidinone-L-serine", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link through a process of forming first an intermediate cysteine sulfenic acid by peroxide oxidation, followed by condensation with the alpha-amido of the following serine residue and the release of water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009443", "l": "pyridoxal 5'-phosphate salvage", "d": ["Any process that generates pyridoxal 5'-phosphate, the active form of vitamin B6, from derivatives of it without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0120185", "l": "MBF transcription complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an MBF transcription complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0075016", "l": "appressorium formation", "d": ["The process in which a swollen, flattened portion of a symbiont filament is formed on or near its host organism, to adhere to and for the purpose of penetrating the host surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901837", "l": "negative regulation of transcription of nucleolar large rRNA by RNA polymerase I", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transcription of nuclear large rRNA transcript mediated by RNA polymerase I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.327400668044291", "identifiers": [{"i": "GO:0030865", "l": "cortical cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106216", "l": "positive regulation of vesicle fusion with Golgi apparatus", "d": ["Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002867", "l": "regulation of B cell deletion", "d": ["Any process that modulates the frequency, rate, or extent of B cell deletion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0035088", "l": "establishment or maintenance of apical/basal cell polarity", "d": ["Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090156", "l": "intracellular sphingolipid homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of sphingolipids within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098785", "l": "biofilm matrix assembly", "d": ["A process that results in the assembly of a biofilm matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036242", "l": "glutamate catabolic process to succinate via 2-oxoglutarate-dependent GABA-transaminase activity", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the 2-oxoglutarate-dependent gamma aminobutyrate (GABA) transaminase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900581", "l": "(17Z)-protosta-17(20),24-dien-3beta-ol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (17Z)-protosta-17(20),24-dien-3beta-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0009809", "l": "lignin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046123", "l": "purine deoxyribonucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any purine deoxyribonucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018378", "l": "cytochrome c-heme linkage via heme-L-cysteine", "d": ["The linkage of cytochromes and other heme proteins to heme via heme-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048035", "l": "heme O catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903784", "l": "positive regulation of sodium ion import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of sodium ion import across the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035852", "l": "horizontal cell localization", "d": ["Any process in which a horizontal cell is transported to, and/or maintained in, a specific location within the inner nuclear layer (INL) of the retina. A horizontal cell is a neuron that laterally connects other neurons in the inner nuclear layer (INL) of the retina. Targeting of retinal neurons to the appropriate lamina is vital to establish the architecture of the retina."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903381", "l": "regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042419", "l": "epinephrine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000473", "l": "positive regulation of hematopoietic stem cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903302", "l": "regulation of pyruvate kinase activity", "d": ["Any process that modulates the frequency, rate or extent of pyruvate kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000335", "l": "regulation of endothelial microparticle formation", "d": ["Any process that modulates the frequency, rate or extent of endothelial microparticle formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006180", "l": "deoxyguanosine salvage", "d": ["Any process that generates deoxyguanosine from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900078", "l": "positive regulation of cellular response to insulin stimulus", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0090083", "l": "regulation of inclusion body assembly", "d": ["Any process that modulates the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072198", "l": "mesenchymal cell proliferation involved in ureter development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046087", "l": "cytidine metabolic process", "d": ["The chemical reactions and pathways involving cytidine, cytosine riboside, a widely distributed nucleoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0007591", "l": "molting cycle, chitin-based cuticle", "d": ["The periodic shedding of part or all of a chitin-based cuticle, which is then replaced by a new cuticle. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090540", "l": "bacterial cellulose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as it occurs in certain types of bacteria, mainly Acetobacter, Sarcina ventriculi and Agrobacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905822", "l": "regulation of mitotic sister chromatid arm separation", "d": ["Any process that modulates the frequency, rate or extent of mitotic sister chromatid arm separation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0005998", "l": "xylulose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of xylulose, the ketopentose threo-2-pentulose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048208", "l": "COPII vesicle coating", "d": ["The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048656", "l": "anther wall tapetum formation", "d": ["The process that gives rise to the anther wall tapetum. This process pertains to the initial formation of a structure from unspecified parts. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060423", "l": "foregut regionalization", "d": ["The pattern specification process that results in the spatial subdivision of an axis or axes along the foregut to define an area or volume in which specific patterns of cell differentiation will take place."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071272", "l": "morphine metabolic process", "d": ["The chemical reactions and pathways involving morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019255", "l": "glucose 1-phosphate metabolic process", "d": ["The chemical reactions and pathways involving glucose 1-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0030852", "l": "regulation of granulocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of granulocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903517", "l": "negative regulation of single strand break repair", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of single strand break repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0060571", "l": "morphogenesis of an epithelial fold", "d": ["The morphogenetic process in which an epithelial sheet bends along a linear axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000559", "l": "regulation of CD24 production", "d": ["Any process that modulates the frequency, rate or extent of CD24 biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0060231", "l": "mesenchymal to epithelial transition", "d": ["A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021633", "l": "optic nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the optic nerve. This process pertains to the physical shaping of a rudimentary structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900680", "l": "positive regulation of ferricrocin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ferricrocin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045746", "l": "negative regulation of Notch signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904640", "l": "response to methionine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902341", "l": "xylitol transmembrane transport", "d": ["The directed movement of a xylitol across a membrane. Xylitol is a polyalcohol (pentane-1,2,3,4,5-pentol), produced by hydrogenation of xylose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140846", "l": "positive regulation of promoter clearance from RNA polymerase II promoter", "d": ["A process that activates or increases the frequency, rate or extent of the transition from the initiation to the elongation phases of transcription by RNA polymerase II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003411", "l": "cell motility involved in camera-type eye morphogenesis", "d": ["Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062212", "l": "regulation of mitotic DNA replication initiation from early origin", "d": ["Any process that modulates the frequency, rate or extent of firing from an early origin of replication involved in mitotic DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000346", "l": "negative regulation of hepatocyte proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050930", "l": "induction of positive chemotaxis", "d": ["Any process that initiates the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.470950656012619", "identifiers": [{"i": "GO:0030162", "l": "regulation of proteolysis", "d": ["Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090045", "l": "positive regulation of deacetylase activity", "d": ["Any process that activates or increases the frequency, rate or extent of deacetylase activity, the catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006362", "l": "transcription elongation by RNA polymerase I", "d": ["The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I specific promoter by the addition of ribonucleotides catalyzed by RNA polymerase I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009245", "l": "lipid A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0070253", "l": "somatostatin secretion", "d": ["The regulated release of somatostatin from secretory granules in the D cells of the pancreas."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071863", "l": "regulation of cell proliferation in bone marrow", "d": ["A process that modulates the frequency, rate or extent of cell proliferation in the bone marrow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1990074", "l": "polyuridylation-dependent mRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end of the target mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006185", "l": "dGDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070862", "l": "negative regulation of protein exit from endoplasmic reticulum", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0051310", "l": "metaphase plate congression", "d": ["The alignment of chromosomes at the metaphase plate (spindle equator), a plane halfway between the poles of the spindle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002509", "l": "central tolerance induction to self antigen", "d": ["Tolerance induction in the central lymphoid organs directed at self antigens."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006201", "l": "GMP catabolic process to IMP", "d": ["The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including inosine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990791", "l": "dorsal root ganglion development", "d": ["The process whose specific outcome is the progression of a dorsal root ganglion over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0045471", "l": "response to ethanol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0009948", "l": "anterior/posterior axis specification", "d": ["The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0048440", "l": "carpel development", "d": ["The process whose specific outcome is the progression of the carpel over time, from its formation to the mature structure. A carpel is an organ (generally believed to be a modified foliar unit) at the centre of a flower, bearing one or more ovules and having its margins fused together or with other carpels to enclose the ovule in an ovary, and consisting also of a stigma and usually a style."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010790", "l": "meiotic sister chromatid cohesion involved in meiosis II", "d": ["The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030211", "l": "heparin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900516", "l": "negative regulation of xylose catabolic process to ethanol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of xylose catabolic process to ethanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902438", "l": "response to vanadate(3-)", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0009553", "l": "embryo sac development", "d": ["The process whose specific outcome is the progression of the embryo sac over time, from its formation to the mature structure. The process begins with the meiosis of the megasporocyte to form four haploid megaspores. Three of the megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. The two polar nuclei fuse resulting in a mononucleate diploid endosperm mother cell. The three antipodal cells degenerate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900610", "l": "F-9775A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of F-9775A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036088", "l": "D-serine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-serine, the D-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120122", "l": "prolactin metabolic process", "d": ["The chemical reactions and pathways involving prolactin, a protein hormone of the anterior pituitary gland that promotes lactation in response to the suckling stimulus of hungry young mammals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003024", "l": "baroreceptor detection of decreased arterial stretch", "d": ["The series of events by which a decrease in diameter of an artery is detected and converted to a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0031943", "l": "regulation of glucocorticoid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902797", "l": "negative regulation of snoRNA processing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018278", "l": "N-terminal peptidyl-threonine deamination", "d": ["The deamination of N-terminal peptidyl-threonine to form peptidyl-2-oxobutanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021753", "l": "superior salivary nucleus development", "d": ["The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903227", "l": "xanthosine metabolic process", "d": ["The chemical reactions and pathways involving xanthosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0032272", "l": "negative regulation of protein polymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010350", "l": "cellular response to magnesium starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of magnesium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007181", "l": "transforming growth factor beta receptor complex assembly", "d": ["The aggregation, arrangement and bonding together of a ligand-bound type II transforming growth factor beta (TGF-beta) receptor dimer with a type I TGF-beta receptor dimer, following ligand binding, to form a heterotetrameric TGF-beta receptor complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046435", "l": "3-(3-hydroxy)phenylpropionate metabolic process", "d": ["The chemical reactions and pathways involving 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002424", "l": "T cell mediated immune response to tumor cell", "d": ["An immune response mediated by a T cell triggered in response to the presence of a tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021620", "l": "hypoglossal nerve formation", "d": ["The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0009804", "l": "coumarin metabolic process", "d": ["The chemical reactions and pathways involving coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044836", "l": "D-xylose fermentation", "d": ["The anaerobic enzymatic conversion of D-xylose to ethanol, yielding energy in the form of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0051552", "l": "flavone metabolic process", "d": ["The chemical reactions and pathways involving flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0010518", "l": "positive regulation of phospholipase activity", "d": ["Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071605", "l": "monocyte chemotactic protein-1 production", "d": ["The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900635", "l": "heptadecane metabolic process", "d": ["The chemical reactions and pathways involving heptadecane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019918", "l": "peptidyl-arginine methylation, to symmetrical-dimethyl arginine", "d": ["The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N'(omega)-dimethyl-L-arginine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070315", "l": "G1 to G0 transition involved in cell differentiation", "d": ["A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters G0 phase, in the context of cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900064", "l": "positive regulation of peroxisome organization", "d": ["Any process that activates or increases the frequency, rate or extent of peroxisome organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "34.336083833758757", "identifiers": [{"i": "GO:0050789", "l": "regulation of biological process", "d": ["Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0002785", "l": "negative regulation of antimicrobial peptide production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075252", "l": "regulation of uredospore formation", "d": ["Any process that modulates the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010842", "l": "retina layer formation", "d": ["The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0044362", "l": "negative regulation of molecular function in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the function of proteins in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902465", "l": "negative regulation of histone H3-K27 trimethylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K27 trimethylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075219", "l": "modulation of zoospore encystment on host", "d": ["Any process that modulates the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002053", "l": "positive regulation of mesenchymal cell proliferation", "d": ["The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070268", "l": "cornification", "d": ["A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032967", "l": "positive regulation of collagen biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097029", "l": "mature conventional dendritic cell differentiation", "d": ["The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0006555", "l": "methionine metabolic process", "d": ["The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0051581", "l": "negative regulation of neurotransmitter uptake", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000435", "l": "negative regulation of protein neddylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein neddylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0003310", "l": "pancreatic A cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014837", "l": "myoblast fate determination involved in skeletal muscle regeneration", "d": ["The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900056", "l": "negative regulation of leaf senescence", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leaf senescence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034729", "l": "histone H3-K79 methylation", "d": ["The modification of histone H3 by addition of a methyl group to lysine at position 79 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905757", "l": "negative regulation of primary cell septum biogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of primary cell septum biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904226", "l": "regulation of glycogen synthase activity, transferring glucose-1-phosphate", "d": ["Any process that modulates the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061380", "l": "superior colliculus development", "d": ["The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904959", "l": "regulation of cytochrome-c oxidase activity", "d": ["Any process that modulates the frequency, rate or extent of cytochrome-c oxidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050668", "l": "positive regulation of homocysteine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving homocysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060040", "l": "retinal bipolar neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061184", "l": "positive regulation of dermatome development", "d": ["Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021666", "l": "rhombomere 5 formation", "d": ["The process that gives rise to rhombomere 5. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042859", "l": "chrysobactin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905356", "l": "regulation of snRNA pseudouridine synthesis", "d": ["Any process that modulates the frequency, rate or extent of snRNA pseudouridine synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902430", "l": "negative regulation of amyloid-beta formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901352", "l": "negative regulation of phosphatidylglycerol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylglycerol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097628", "l": "distal tip cell migration", "d": ["The orderly movement of a distal tip cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046091", "l": "deoxyadenosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001129", "l": "methane biosynthetic process from dimethylamine", "d": ["The chemical reactions and pathways resulting in the formation of a methane from a dimethylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071679", "l": "commissural neuron axon guidance", "d": ["The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905171", "l": "positive regulation of protein localization to phagocytic vesicle", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to phagocytic vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0003062", "l": "regulation of heart rate by chemical signal", "d": ["The regulation of the rate of heart contraction mediated by chemical signaling, hormonal, autocrine or paracrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901833", "l": "all-trans-neoxanthin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of all-trans-neoxanthin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072168", "l": "specification of anterior mesonephric tubule identity", "d": ["The process in which the tubules of the anterior mesonephros acquire their identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019584", "l": "galactonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of galactonate, the anion of galactonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001680", "l": "tRNA 3'-terminal CCA addition", "d": ["Post-transcriptional addition of the terminal 3' CCA sequence to a tRNA which does not encode this sequence within the primary transcript. CCA addition proceeds by the sequential addition of CTP, CTP, and then ATP to the 3' end of the tRNA, yielding a diphosphate with each nucleotide addition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902596", "l": "negative regulation of DNA replication origin binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication origin binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0098760", "l": "response to interleukin-7", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002316", "l": "follicular B cell differentiation", "d": ["The process in which a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033146", "l": "regulation of intracellular estrogen receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051415", "l": "microtubule nucleation by interphase microtubule organizing center", "d": ["The 'de novo' formation of a microtubule by the interphase microtubule organizing center during interphase, the stage of cell cycle between successive rounds of chromosome segregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0140499", "l": "negative regulation of mitotic spindle assembly checkpoint signaling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of negative regulation of mitotic spindle assembly checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901355", "l": "response to rapamycin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071367", "l": "cellular response to brassinosteroid stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072352", "l": "tricarboxylic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0033366", "l": "protein localization to secretory granule", "d": ["A process in which a protein is transported to, or maintained in, a location within a secretory granule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048236", "l": "plant-type sporogenesis", "d": ["The formation of plant spores derived from the products of meiosis. The spore gives rise to gametophytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0033397", "l": "zeatin metabolic process", "d": ["The chemical reactions and pathways involving zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0036177", "l": "filamentous growth of a population of unicellular organisms in response to pH", "d": ["The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904604", "l": "negative regulation of advanced glycation end-product receptor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of advanced glycation end-product receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0015835", "l": "peptidoglycan transport", "d": ["The directed movement of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000206", "l": "regulation of ribosomal small subunit export from nucleus", "d": ["Any process that modulates the frequency, rate or extent of ribosomal small subunit export from nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070684", "l": "seminal clot liquefaction", "d": ["The reproductive process in which coagulated semen becomes liquid following ejaculation, allowing the progressive release of motile spermatozoa."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:1990896", "l": "protein localization to cell cortex of cell tip", "d": ["A process in which a protein is transported to, or maintained in, the cell cortex of the cell tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002411", "l": "T cell tolerance induction to tumor cell", "d": ["A process of tolerance induction dependent on T cells which leads to immunological tolerance of a tumor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006710", "l": "androgen catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033605", "l": "positive regulation of catecholamine secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0006476", "l": "protein deacetylation", "d": ["The removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030573", "l": "bile acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010600", "l": "regulation of auxin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1901862", "l": "negative regulation of muscle tissue development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009989", "l": "cell-matrix recognition", "d": ["Cell recognition that involves the interaction of the cell with the extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0039507", "l": "suppression by virus of host molecular function", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002348", "l": "central B cell positive selection", "d": ["Any process leading to positive selection of B cells in the bone marrow. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032286", "l": "central nervous system myelin maintenance", "d": ["The process in which the structure and material content of mature central nervous system myelin is kept in a functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000570", "l": "positive regulation of T-helper 2 cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 2 cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062001", "l": "negative regulation of cardiac endothelial to mesenchymal transition", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac endothelial to mesenchymal transition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060701", "l": "negative regulation of ribonuclease activity", "d": ["Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000856", "l": "negative regulation of mineralocorticoid secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mineralocorticoid secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110119", "l": "positive regulation of very-low-density lipoprotein particle clearance", "d": ["Any process that increases the frequency, rate or extent of very-low-density lipoprotein particle clearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060663", "l": "apoptotic process involved in salivary gland cavitation", "d": ["Any apoptotic process in which the solid core of the gland is hollowed out to form the duct."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905062", "l": "positive regulation of cardioblast proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of cardioblast proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905416", "l": "regulation of amoeboid sperm motility", "d": ["Any process that modulates the frequency, rate or extent of amoeboid sperm motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901157", "l": "neomycin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of neomycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003405", "l": "optic vesicle elongation", "d": ["The developmental growth that results in the lengthening of the optic vesicle in the posterior direction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.071082486141265", "identifiers": [{"i": "GO:0002791", "l": "regulation of peptide secretion", "d": ["Any process that modulates the frequency, rate, or extent of peptide secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009206", "l": "purine ribonucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0002446", "l": "neutrophil mediated immunity", "d": ["Any process involved in the carrying out of an immune response by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060817", "l": "inactivation of paternal X chromosome", "d": ["Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes specifically on the paternal X-chromosome in the XX sex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0071604", "l": "transforming growth factor beta production", "d": ["The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071673", "l": "positive regulation of smooth muscle cell chemotaxis", "d": ["Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090348", "l": "regulation of cellular organofluorine metabolic process", "d": ["Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045688", "l": "regulation of antipodal cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of antipodal cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099049", "l": "clathrin coat assembly involved in endocytosis", "d": ["The process that results in the assembly of clathrin triskelia into a clathrin cage during endocytosis. Clathrin is recruited to the plasma membrane via interaction with scaffolding proteins that bridge between clathtin and cell surface receptors. Clathrin coat formation is concomittant with coated pit formation leading to endocytic vesicle formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061972", "l": "dermal bone morphogenesis", "d": ["The process in which bone which forms superficially in the organism are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021627", "l": "olfactory nerve morphogenesis", "d": ["The process in which the anatomical structure of the olfactory nerve is generated and organized. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001075", "l": "negative regulation of metanephric ureteric bud development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of metanephric ureteric bud development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046006", "l": "regulation of activated T cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of activated T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070759", "l": "negative regulation of interleukin-35-mediated signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of an interleukin-35-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030205", "l": "dermatan sulfate metabolic process", "d": ["The chemical reactions and pathways involving dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. They are important components of ground substance or intercellular cement of skin and some connective tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905509", "l": "protein localization to interphase microtubule organizing center", "d": ["A process in which a protein is transported to, or maintained in, a location within an interphase microtubule organizing center."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900279", "l": "regulation of CD4-positive, alpha-beta T cell costimulation", "d": ["Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003343", "l": "septum transversum development", "d": ["The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019313", "l": "allose metabolic process", "d": ["The chemical reactions and pathways involving allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904990", "l": "regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003342", "l": "proepicardium development", "d": ["The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042639", "l": "telogen", "d": ["The resting phase of hair cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0120246", "l": "acetylenic compound metabolic process", "d": ["The chemical reactions and pathways involving an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051771", "l": "negative regulation of nitric-oxide synthase biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016269", "l": "O-glycan processing, core 3", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 3 O-glycan structure, GlcNAc-beta-(1->3)-GalNAc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001298", "l": "N(omega),N(omega)-dimethyl-L-arginine metabolic process", "d": ["The chemical reactions and pathways involving N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009201", "l": "ribonucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.740773438186515", "identifiers": [{"i": "GO:0051604", "l": "protein maturation", "d": ["Any process leading to the attainment of the full functional capacity of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110037", "l": "regulation of nematode male tail tip morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of nematode male tail tip morphogenesis, the process in which the anatomical structure of the adult male tail tip is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003412", "l": "establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis", "d": ["The specification and formation of the apicobasal polarity of an epithelial cell that contributes to the shaping of a camera-type eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0035195", "l": "miRNA-mediated gene silencing", "d": ["A post-transcriptional gene silencing pathway in which regulatory microRNAs (miRNAs) elicit silencing of specific target genes. miRNAs are endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate protein production by either of two posttranscriptional mechanisms: endonucleolytic cleavage of the RNA (often mRNA) or mRNA translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA. miRNAs are present in all the animals and in plants, whereas siRNAs are present in lower animals and in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070844", "l": "polyubiquitinated protein transport", "d": ["The directed movement of polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042840", "l": "D-glucuronate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-glucuronate, the D-enantiomer of glucuronate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905429", "l": "response to glycine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046931", "l": "pore complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a pore complex. A pore complex is a small opening in a membrane that allows the passage of liquids and/or gases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046162", "l": "heme C metabolic process", "d": ["The chemical reactions and pathways involving heme c, a derivative of heme found in cytochromes c, b4, and f."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021512", "l": "spinal cord anterior/posterior patterning", "d": ["The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060755", "l": "negative regulation of mast cell chemotaxis", "d": ["Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050835", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019686", "l": "purine nucleoside interconversion", "d": ["The chemical reactions and pathways by which a purine nucleoside is synthesized from another purine nucleoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902380", "l": "positive regulation of endoribonuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of endoribonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0006517", "l": "protein deglycosylation", "d": ["The removal of sugar residues from a glycosylated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032086", "l": "regulation of type III site-specific deoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of a type III restriction endodeoxyribonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097327", "l": "response to antineoplastic agent", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antineoplastic agent stimulus. An antineoplastic agent is a substance that inhibits or prevents the proliferation of neoplasms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032630", "l": "interleukin-26 production", "d": ["The appearance of interleukin-26 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901952", "l": "negative regulation of anterograde dense core granule transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anterograde dense core granule transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.626192998115265", "identifiers": [{"i": "GO:0009058", "l": "biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0010823", "l": "negative regulation of mitochondrion organization", "d": ["Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901081", "l": "negative regulation of relaxation of smooth muscle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of smooth muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045901", "l": "positive regulation of translational elongation", "d": ["Any process that activates or increases the frequency, rate or extent of translational elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010910", "l": "positive regulation of heparan sulfate proteoglycan biosynthesis by positive regulation of epimerase activity", "d": ["Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis by an increase in epimerase activity. This epimerase activity catalyzes the reaction that converts D-glucuronate into its diastereoisomer in heparan sulfate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039644", "l": "suppression by virus of host NF-kappaB cascade", "d": ["Any process in which a virus stops, prevents, or reduces a host NF-kappaB cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018145", "l": "protein-DNA covalent cross-linking via peptidyl-serine", "d": ["The formation of a covalent cross-link between DNA and a peptidyl-serine residue by the formation of O-(phospho-5'-DNA)-L-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902951", "l": "negative regulation of dendritic spine maintenance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dendritic spine maintenance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.316418070386277", "identifiers": [{"i": "GO:0016064", "l": "immunoglobulin mediated immune response", "d": ["An immune response mediated by immunoglobulins, whether cell-bound or in solution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036489", "l": "neuromelanin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of neuromelanin. Neuromelanin is a polymer of 5,6-dihydroxyindole monomers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000724", "l": "positive regulation of cardiac vascular smooth muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1904201", "l": "regulation of iodide transport", "d": ["Any process that modulates the frequency, rate or extent of iodide transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051694", "l": "pointed-end actin filament capping", "d": ["The binding of a protein or protein complex to the pointed (or minus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0140632", "l": "canonical inflammasome complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an inflammasome complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060664", "l": "epithelial cell proliferation involved in salivary gland morphogenesis", "d": ["The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009946", "l": "proximal/distal axis specification", "d": ["The establishment, maintenance and elaboration of the proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018178", "l": "peptidyl-threonine adenylylation", "d": ["The adenylylation of peptidyl-threonine to form peptidyl-O-(phospho-5'-adenosine)-L-threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060244", "l": "negative regulation of cell proliferation involved in contact inhibition", "d": ["Any process that stops, prevents or reduces the rate or extent of cell proliferation in response to cell density."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0080036", "l": "regulation of cytokinin-activated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of cytokinin signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000441", "l": "negative regulation of toll-like receptor 15 signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 15 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090676", "l": "calcium ion transmembrane transport via low voltage-gated calcium channel", "d": ["A process in which a calcium ion is transported from one side of a membrane to the other by means of a low voltage-gated calcium channel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0044182", "l": "filamentous growth of a population of unicellular organisms", "d": ["The process in which a group of unicellular organisms grow in a threadlike, filamentous shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0044553", "l": "modulation of biological quality in another organism", "d": ["Any process that modulates the frequency, rate or extent of a biological quality in another organism. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072119", "l": "head kidney structural organization", "d": ["The process that contributes to the act of creating the structural organization of the head kidney. This process pertains to the physical shaping of a rudimentary structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046852", "l": "positive regulation of bone remodeling", "d": ["Any process that activates or increases the frequency, rate or extent of bone remodeling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:1905037", "l": "autophagosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097082", "l": "vascular associated smooth muscle cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019589", "l": "anaerobic glycerol catabolic process to propane-1,3-diol", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol into propane-1,3-diol and water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062029", "l": "positive regulation of stress granule assembly", "d": ["Any process that starts or increases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.468544520863134", "identifiers": [{"i": "GO:0090529", "l": "cell septum assembly", "d": ["The assembly and arrangement of a cellular component that is composed of peptidoglycan and often chitin in addition to other materials and usually forms perpendicular to the long axis of a cell or hypha. It grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061187", "l": "regulation of rDNA heterochromatin formation", "d": ["Any process that modulates the rate, frequency, or extent of rDNA heterochromatin formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.415093686714229", "identifiers": [{"i": "GO:0021782", "l": "glial cell development", "d": ["The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0021515", "l": "cell differentiation in spinal cord", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080167", "l": "response to karrikin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a karrikin stimulus. Karrikins are signaling molecules in smoke from burning vegetation that trigger seed germination for many angiosperms (flowering plants)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903752", "l": "positive regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "d": ["Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902146", "l": "positive regulation of response to cell cycle checkpoint signaling", "d": ["Any process that activates or increases the frequency, rate or extent of response to cell cycle checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.768275768238951", "identifiers": [{"i": "GO:0016054", "l": "organic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061790", "l": "dense core granule docking", "d": ["The initial attachment of a dense core granule membrane to the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060534", "l": "trachea cartilage development", "d": ["The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903184", "l": "L-dopa metabolic process", "d": ["The chemical reactions and pathways involving L-dopa."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046333", "l": "octopamine metabolic process", "d": ["The chemical reactions and pathways involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904026", "l": "regulation of collagen fibril organization", "d": ["Any process that modulates the frequency, rate or extent of collagen fibril organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048720", "l": "posterior cibarial plate morphogenesis", "d": ["The process in which the anatomical structures of the posterior cibarial plate are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010874", "l": "regulation of cholesterol efflux", "d": ["Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021917", "l": "somatic motor neuron fate commitment", "d": ["The commitment of unspecified motor neurons to specific motor neuron cell along the anterior-posterior axis of the spinal cord and their capacity to differentiate into specific motor neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0060756", "l": "foraging behavior", "d": ["Behavior by which an organism locates food."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046584", "l": "enniatin metabolic process", "d": ["The chemical reactions and pathways involving enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.959712637402532", "identifiers": [{"i": "GO:0034504", "l": "protein localization to nucleus", "d": ["A process in which a protein transports or maintains the localization of another protein to the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905654", "l": "regulation of artery smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of artery smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903565", "l": "negative regulation of protein localization to cilium", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001563", "l": "detection of protozoan", "d": ["The series of events in which a stimulus from a protozoan is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0014015", "l": "positive regulation of gliogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097211", "l": "cellular response to gonadotropin-releasing hormone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:1903729", "l": "regulation of plasma membrane organization", "d": ["Any process that modulates the frequency, rate or extent of plasma membrane organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071909", "l": "determination of stomach left/right asymmetry", "d": ["Determination of the asymmetric location of the stomach with respect to the left and right halves of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042733", "l": "embryonic digit morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060978", "l": "angiogenesis involved in coronary vascular morphogenesis", "d": ["Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030277", "l": "maintenance of gastrointestinal epithelium", "d": ["Protection of epithelial surfaces of the gastrointestinal tract from proteolytic and caustic digestive agents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048702", "l": "embryonic neurocranium morphogenesis", "d": ["The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. The neurocranium is the portion of the vertebrate skull surrounding the brain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071028", "l": "nuclear mRNA surveillance", "d": ["A process that identifies and degrades defective or aberrant mRNAs within the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007388", "l": "posterior compartment specification", "d": ["The process involved in the specification of cell identity in the posterior compartments of the segmented embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0032366", "l": "intracellular sterol transport", "d": ["The directed movement of sterols within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0062107", "l": "regulation of protein localization to non-growing cell tip", "d": ["Any process that modulates the frequency, rate or extent of protein localization to a non-growing cell tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.762734528272794", "identifiers": [{"i": "GO:0055080", "l": "monoatomic cation homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of monoatomic cations within an organism or cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0060037", "l": "pharyngeal system development", "d": ["The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:1901891", "l": "regulation of cell septum assembly", "d": ["Any process that modulates the frequency, rate or extent of cell septum assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.825956045430587", "identifiers": [{"i": "GO:0042692", "l": "muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a muscle cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901737", "l": "(R)-mevalonic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (R)-mevalonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072285", "l": "mesenchymal to epithelial transition involved in metanephric renal vesicle formation", "d": ["A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0140074", "l": "cardiac endothelial to mesenchymal transition", "d": ["A transition where a cardiac endothelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. Endocardial cells (specialized endothelial cells that line the heart) undergo EndMT, and give rise to mesenchymal cells necessary for proper heart development. EndMT, specifically generates valve progenitor cells that give rise to the mitral and tricuspid valves. EndMT also contributes to endocardial cushion formation, as well as to generation of cardiac fibroblasts and smooth muscle cells, but not cardiac myocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002803", "l": "positive regulation of antibacterial peptide production", "d": ["Any process that activates or increases the frequency, rate, or extent of antibacterial peptide production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030207", "l": "chondroitin sulfate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903354", "l": "regulation of distal tip cell migration", "d": ["Any process that modulates the frequency, rate or extent of distal tip cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075241", "l": "positive regulation of zoospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036154", "l": "diacylglycerol acyl-chain remodeling", "d": ["Remodeling the acyl chains of diacylglycerol, through sequential deacylation and re-acylation reactions, to generate diacylglycerol containing different types of fatty acid acyl chains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051660", "l": "establishment of centrosome localization", "d": ["The directed movement of the centrosome to a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033540", "l": "fatty acid beta-oxidation using acyl-CoA oxidase", "d": ["A fatty acid beta-oxidation pathway in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039666", "l": "virion attachment to host cell pilus", "d": ["The process by which a virion attaches to a host cell by binding to a pilus on the host cell surface. Pili are retractile filaments that protrude from gram-negative bacteria. Filamentous viruses can attach to the pilus tip, whereas icosahedral viruses can attach to the pilus side."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046010", "l": "positive regulation of circadian sleep/wake cycle, non-REM sleep", "d": ["Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035518", "l": "histone H2A monoubiquitination", "d": ["The modification of histone H2A by addition of a single ubiquitin group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000670", "l": "positive regulation of dendritic cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042474", "l": "middle ear morphogenesis", "d": ["The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904211", "l": "membrane protein proteolysis involved in retrograde protein transport, ER to cytosol", "d": ["Any membrane protein proteolysis that is involved in retrograde protein transport, ER to cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1901215", "l": "negative regulation of neuron death", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neuron death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0002181", "l": "cytoplasmic translation", "d": ["The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0065001", "l": "specification of axis polarity", "d": ["The pattern specification process in which the polarity of a body or organ axis is established and maintained."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002551", "l": "mast cell chemotaxis", "d": ["The movement of a mast cell in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090055", "l": "positive regulation of silent mating-type cassette heterochromatin formation", "d": ["Any process that increases the frequency, rate, or extent of heterochromatin formation at silent mating-type cassette."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905433", "l": "negative regulation of retrograde trans-synaptic signaling by neuropeptide", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0060078", "l": "regulation of postsynaptic membrane potential", "d": ["Any process that modulates the potential difference across a post-synaptic membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.819490397197882", "identifiers": [{"i": "GO:0050727", "l": "regulation of inflammatory response", "d": ["Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0042816", "l": "vitamin B6 metabolic process", "d": ["The chemical reactions and pathways involving any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901457", "l": "regulation of response to acetate", "d": ["Any process that modulates the frequency, rate or extent of response to acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046304", "l": "2-nitropropane catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-nitropropane, a clear, colorless liquid with a mild, fruity odor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900072", "l": "positive regulation of sulfite transport", "d": ["Any process that activates or increases the frequency, rate or extent of sulfite transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140635", "l": "neutrophil dispersal", "d": ["The movement of a neutrophil away from the site of wound or infection following its initial migration to the site."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900718", "l": "positive regulation of violaceol II biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of violaceol II biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:0002339", "l": "B cell selection", "d": ["The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1905153", "l": "regulation of membrane invagination", "d": ["Any process that modulates the frequency, rate or extent of membrane invagination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010523", "l": "negative regulation of calcium ion transport into cytosol", "d": ["Any process that decreases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150069", "l": "negative regulation of tubulin deacetylase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033495", "l": "ferulate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0045455", "l": "ecdysteroid metabolic process", "d": ["The chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids ubiquitous in insects and other arthropods, in which they initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031549", "l": "negative regulation of brain-derived neurotrophic factor receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016060", "l": "metarhodopsin inactivation", "d": ["The process in which metarhodopsin is prevented from generating molecular signals. Activated rhodopsin (R*) is inactivated by a two-step process: first, R* is phosphorylated by rhodopsin kinase which lowers the activity of R*. Second, the protein arrestin binds to phosphorylated R* to de-activate it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060163", "l": "subpallium neuron fate commitment", "d": ["The process in which in the subpallium, the developmental fate of a cell becomes restricted such that it will develop into a neuron. The subpallium is the base region of the telencephalon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905193", "l": "negative regulation of chloroplast fission", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chloroplast fission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900900", "l": "negative regulation of heptadecane metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905070", "l": "anterior visceral endoderm cell migration", "d": ["The orderly movement of an anterior visceral endoderm cell from one site to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901696", "l": "cannabinoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cannabinoid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002632", "l": "negative regulation of granuloma formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051475", "l": "glucosylglycerol transmembrane transport", "d": ["The directed movement of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol, across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032734", "l": "positive regulation of interleukin-11 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-11 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0046662", "l": "regulation of egg-laying behavior", "d": ["Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019129", "l": "peptidyl-leucine racemization", "d": ["The racemization of peptidyl-leucine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002297", "l": "T-helper 2 cell lineage commitment", "d": ["The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 2 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to extracellular organisms such as helminths, enhanced production of particular antibody isotypes, and pathological conditions such as allergy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061067", "l": "negative regulation of dauer larval development", "d": ["Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018429", "l": "copper incorporation into copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide", "d": ["The incorporation of copper into a 4Cu-S copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035608", "l": "protein deglutamylation", "d": ["The removal of a glutamate residue from a protein. Glutamate residues in proteins can be gene-encoded, or added as side chains during the protein modification process of polyglutamylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016557", "l": "peroxisome membrane biogenesis", "d": ["The process in which a peroxisome membrane is synthesized, aggregates, and bonds together."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034180", "l": "negative regulation of toll-like receptor 13 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 13 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060793", "l": "sweat gland placode formation", "d": ["The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0090030", "l": "regulation of steroid hormone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090446", "l": "negative regulation of nematode larval development, heterochronic", "d": ["Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and decreases the rate at which this time point is reached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902859", "l": "propionyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of propionyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006481", "l": "C-terminal protein methylation", "d": ["The methylation of the C-terminal amino acid of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030844", "l": "positive regulation of intermediate filament depolymerization", "d": ["Any process that activates or increases the frequency, rate or extent of intermediate filament depolymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1905915", "l": "regulation of cell differentiation involved in phenotypic switching", "d": ["Any process that modulates the frequency, rate or extent of cell differentiation involved in phenotypic switching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062168", "l": "negative regulation of plus-end directed microtubule sliding", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of plus-end directed microtubule sliding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1900264", "l": "positive regulation of DNA-directed DNA polymerase activity", "d": ["Any process that activates or increases the frequency, rate or extent of DNA-directed DNA polymerase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.426153789046865", "identifiers": [{"i": "GO:0002706", "l": "regulation of lymphocyte mediated immunity", "d": ["Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900836", "l": "positive regulation of emericellin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of emericellin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034373", "l": "intermediate-density lipoprotein particle remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within an intermediate-density lipoprotein particle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035322", "l": "mesenchymal cell migration involved in limb bud formation", "d": ["The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010787", "l": "COPI coating of Golgi vesicle, inter-Golgi cisterna", "d": ["The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of inter-Golgi cisterna transport vesicles, forming a vesicle coat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010748", "l": "negative regulation of long-chain fatty acid import across plasma membrane", "d": ["Any process that decreases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010907", "l": "positive regulation of glucose metabolic process", "d": ["Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0044781", "l": "bacterial-type flagellum organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051133", "l": "regulation of NK T cell activation", "d": ["Any process that modulates the frequency, rate or extent of natural killer T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000716", "l": "negative regulation of maintenance of mitotic sister chromatid cohesion, arms", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001313", "l": "UDP-4-deoxy-4-formamido-beta-L-arabinopyranose metabolic process", "d": ["The chemical reactions and pathways involving a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032443", "l": "regulation of ergosterol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060268", "l": "negative regulation of respiratory burst", "d": ["Any process that decreases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0034111", "l": "negative regulation of homotypic cell-cell adhesion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.240853996207278", "identifiers": [{"i": "GO:0043467", "l": "regulation of generation of precursor metabolites and energy", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033473", "l": "indoleacetic acid conjugate metabolic process", "d": ["The chemical reactions and pathways involving any indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1905063", "l": "regulation of vascular associated smooth muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0032056", "l": "positive regulation of translation in response to stress", "d": ["Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900540", "l": "fumonisin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fumonisin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902007", "l": "regulation of toxin transport", "d": ["Any process that modulates the frequency, rate or extent of toxin transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090180", "l": "positive regulation of thiamine biosynthetic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007615", "l": "anesthesia-resistant memory", "d": ["The memory process that results in the formation of consolidated memory resistant to disruption of the patterned activity of the brain, without requiring protein synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072055", "l": "renal cortex development", "d": ["The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061144", "l": "alveolar secondary septum development", "d": ["The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045339", "l": "farnesyl diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of farnesyl diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015871", "l": "choline transport", "d": ["The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000221", "l": "negative regulation of pseudohyphal growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0075733", "l": "intracellular transport of virus", "d": ["The directed movement of a virus, or part of a virus, within the host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009700", "l": "indole phytoalexin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990771", "l": "clathrin-dependent extracellular exosome endocytosis", "d": ["The clathrin-mediated endocytosis of an extracellular exosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905067", "l": "negative regulation of canonical Wnt signaling pathway involved in heart development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018922", "l": "iprodione metabolic process", "d": ["The chemical reactions and pathways involving prodione, a colorless, odorless crystal. It is used as a dicarboximide contact fungicide to control a wide variety of crop diseases by inhibiting the germination of spores and the growth of the fungal mat (mycelium)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902009", "l": "positive regulation of toxin transport", "d": ["Any process that activates or increases the frequency, rate or extent of toxin transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046360", "l": "2-oxobutyrate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1902686", "l": "mitochondrial outer membrane permeabilization involved in programmed cell death", "d": ["The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of a programmed cell death process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070121", "l": "Kupffer's vesicle development", "d": ["The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905614", "l": "negative regulation of developmental vegetative growth", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of developmental vegetative growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0046864", "l": "isoprenoid transport", "d": ["The directed movement of isoprenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Isoprenoids comprise a group of compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035281", "l": "pre-miRNA export from nucleus", "d": ["Transport of pre-microRNAs (pre-miRNAs) from the nucleus to the cytoplasm. Pre-miRNAs are a ~60-70 nucleotide stem loop intermediate in miRNA production, produced by the nuclear cleavage of a primary miRNA (pri-mRNA) transcript. Pre-miRNAs are transported from the nucleus to the cytoplasm where further cleavage occurs to produce a mature miRNA product."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098736", "l": "negative regulation of the force of heart contraction", "d": ["Any process that decreases the force of heart muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900485", "l": "positive regulation of protein targeting to vacuolar membrane", "d": ["Any process that activates or increases the frequency, rate or extent of protein targeting to vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0000245", "l": "spliceosomal complex assembly", "d": ["The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110008", "l": "ncRNA deadenylation", "d": ["Shortening of the poly(A) tail of a nuclear-transcribed ncRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905374", "l": "response to homocysteine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010996", "l": "response to auditory stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032425", "l": "positive regulation of mismatch repair", "d": ["Any process that activates or increases the frequency, rate or extent of mismatch repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002892", "l": "regulation of type II hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of type II hypersensitivity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0019883", "l": "antigen processing and presentation of endogenous antigen", "d": ["The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900038", "l": "negative regulation of cellular response to hypoxia", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hypoxia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007594", "l": "puparial adhesion", "d": ["The adhesion of the puparia of Diptera to their substrate; normally effected by a 'glue' secreted by the larval salivary gland and expectorated at the time of pupariation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904412", "l": "regulation of cardiac ventricle development", "d": ["Any process that modulates the frequency, rate or extent of cardiac ventricle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090289", "l": "regulation of osteoclast proliferation", "d": ["Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0018211", "l": "peptidyl-tryptophan modification", "d": ["The chemical alteration of a tryptophan residue in a peptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.642927237245431", "identifiers": [{"i": "GO:0009895", "l": "negative regulation of catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0007097", "l": "nuclear migration", "d": ["The directed movement of the nucleus to a specific location within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0021823", "l": "cerebral cortex tangential migration using cell-cell interactions", "d": ["The process in which neurons interact with each other to promote migration along a tangential plane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.024910309174537", "identifiers": [{"i": "GO:0042330", "l": "taxis", "d": ["The directed movement of a motile cell or organism in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900091", "l": "regulation of raffinose biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of raffinose biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039645", "l": "modulation by virus of host G1/S transition checkpoint", "d": ["Any viral process that modulates the frequency, rate or extent of the host cell G1/S transition checkpoint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070809", "l": "negative regulation of Hulle cell development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901281", "l": "fructoselysine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fructoselysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.569439710577498", "identifiers": [{"i": "GO:0001959", "l": "regulation of cytokine-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048814", "l": "regulation of dendrite morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of dendrite morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902463", "l": "protein localization to cell leading edge", "d": ["A process in which a protein is transported to, or maintained in, a location within a cell leading edge."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0043153", "l": "entrainment of circadian clock by photoperiod", "d": ["The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061472", "l": "karyomere membrane fusion", "d": ["Process whereby karyomere membranes fuse during interphase to form a single lobed nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071274", "l": "isoquinoline alkaloid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043438", "l": "acetoacetic acid metabolic process", "d": ["The chemical reactions and pathways involving acetoacetic acid, 3-oxobutanoic acid; the empirical formula is C4H6O3 or CH3COCH2COOH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010024", "l": "phytochromobilin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytochromobilin, which involves the oxidative cleavage of heme by a heme oxygenase(HO) to form biliverdin IX alpha."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051410", "l": "detoxification of nitrogen compound", "d": ["Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099141", "l": "cellular response to protozoan", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0002776", "l": "antimicrobial peptide secretion", "d": ["The regulated release of an antimicrobial peptide from a cell or a tissue. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904818", "l": "visceral peritoneum development", "d": ["The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090103", "l": "cochlea morphogenesis", "d": ["The process in which the cochlea is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0009453", "l": "energy taxis", "d": ["The directed movement of a motile cell or organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0015740", "l": "C4-dicarboxylate transport", "d": ["The directed movement of a C4-dicarboxylate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A C4-dicarboxylate is the anion of a dicarboxylic acid that contains four carbon atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0061307", "l": "cardiac neural crest cell differentiation involved in heart development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0110116", "l": "regulation of compound eye photoreceptor cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0044407", "l": "single-species biofilm formation in or on host organism", "d": ["A process in which microorganisms of the same species attach to and grow in or on a host species, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the microorganisms' growth rate and gene transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003297", "l": "heart wedging", "d": ["The morphogenetic process in which the aorta inserts between the atrioventricular valves, contributing to the shaping of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0007533", "l": "mating type switching", "d": ["The conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0032682", "l": "negative regulation of chemokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of chemokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045617", "l": "negative regulation of keratinocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090513", "l": "L-histidine transmembrane import into vacuole", "d": ["The directed movement of L-histidine into the vacuole across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.567074069783395", "identifiers": [{"i": "GO:0051701", "l": "biological process involved in interaction with host", "d": ["An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901195", "l": "positive regulation of formation of translation preinitiation complex", "d": ["Any process that activates or increases the frequency, rate or extent of formation of translation preinitiation complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098777", "l": "protein secretion by the type VIII secretion system", "d": ["Protein secretion through the outer membrane via the mechanism used for the secretion of curli subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034241", "l": "positive regulation of macrophage fusion", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070786", "l": "positive regulation of growth of unicellular organism as a thread of attached cells", "d": ["Any process that activates or increases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007491", "l": "sternite morphogenesis", "d": ["The process in which the anatomical structures of the sternite are generated and organized. The sternite is the plate or sclerite on the underside of a body segment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000350", "l": "generation of catalytic spliceosome for second transesterification step", "d": ["Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007390", "l": "germ-band shortening", "d": ["The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001107", "l": "negative regulation of Rho guanyl-nucleotide exchange factor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000890", "l": "cellodextrin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a cellodextrin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021651", "l": "rhombomere 1 morphogenesis", "d": ["The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051491", "l": "positive regulation of filopodium assembly", "d": ["Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010444", "l": "guard mother cell differentiation", "d": ["The process in which a meristemoid acquires the specialized features of a guard mother cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902311", "l": "regulation of copper ion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of copper ion transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000594", "l": "positive regulation of metanephric DCT cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of metanephric DCT cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035429", "l": "gluconate transmembrane transport", "d": ["The process in which gluconate is transported across a membrane. Gluconate is the aldonic acid derived from glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036344", "l": "platelet morphogenesis", "d": ["Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0033750", "l": "ribosome localization", "d": ["A process in which a ribosome is transported to, and/or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097151", "l": "positive regulation of inhibitory postsynaptic potential", "d": ["Any process that activates or increases the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071728", "l": "beak development", "d": ["The progression of the beak over time from its initial formation until its mature state. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043051", "l": "regulation of pharyngeal pumping", "d": ["Any process that modulates the contraction and relaxation movements of the pharyngeal muscle that mediates feeding in nematodes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0044633", "l": "modulation of complement activation, alternative pathway in another organism", "d": ["A process that modulates the frequency, rate or extent of complement activation, via the alternative pathway, in a different organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051473", "l": "glucosylglycerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048940", "l": "anterior lateral line nerve glial cell morphogenesis involved in differentiation", "d": ["The process in which the structures of a glial cell in the anterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the anterior lateral line nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032898", "l": "neurotrophin production", "d": ["The appearance of a neurotrophin due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. A neurotrophin is any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900668", "l": "negative regulation of endocrocin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endocrocin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046108", "l": "uridine metabolic process", "d": ["The chemical reactions and pathways involving uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000936", "l": "regulation of cellotriose catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellotriose catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021742", "l": "abducens nucleus development", "d": ["The process whose specific outcome is the progression of the abducens nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062165", "l": "positive regulation of pseudohyphal septin ring assembly", "d": ["Any process that increases the rate, frequency or extent of pseudohyphal septin ring formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0097168", "l": "mesenchymal stem cell proliferation", "d": ["The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045953", "l": "negative regulation of natural killer cell mediated cytotoxicity", "d": ["Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051878", "l": "lateral element assembly", "d": ["The cell cycle process in which lateral elements are formed. Axial elements form a proteinaceous core between the two sister chromatids of each chromosome; the two axial elements then connect along their entire lengths by fine fibers known as transverse filaments, forming the lateral elements."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0050796", "l": "regulation of insulin secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of insulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900690", "l": "negative regulation of gliotoxin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gliotoxin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0009735", "l": "response to cytokinin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031648", "l": "protein destabilization", "d": ["Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055112", "l": "delamination involved in gastrulation with mouth forming second", "d": ["The splitting or migration of one epithelial sheet into two involved in the process of deuterostomic gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072115", "l": "head kidney morphogenesis", "d": ["The process in which the anatomical structures of the head kidney are generated and organized. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0070631", "l": "spindle pole body localization", "d": ["Any process in which a spindle pole body is transported to, or maintained in, a specific location. A spindle pole body is a type of microtubule organizing center found in fungal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0080121", "l": "AMP transport", "d": ["The directed movement of AMP, adenosine monophosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.939870552020253", "identifiers": [{"i": "GO:0007517", "l": "muscle organ development", "d": ["The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0140246", "l": "protein catabolic process at synapse", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein at a synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140515", "l": "mitotic nuclear bridge organization", "d": ["A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the mitotic nuclear bridge during closed mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0051208", "l": "sequestering of calcium ion", "d": ["The process of binding or confining calcium ions such that they are separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021656", "l": "rhombomere 2 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 2. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0098516", "l": "detection of high humidity", "d": ["The series of events in which high humidity is detected and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032058", "l": "positive regulation of translational initiation in response to stress", "d": ["Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071034", "l": "CUT catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cryptic unstable transcripts (CUTs)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902963", "l": "negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904947", "l": "folate import into mitochondrion", "d": ["The process in which folic acid is transported from the cytosol into the mitochondrial matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061064", "l": "negative regulation of nematode larval development", "d": ["Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035164", "l": "embryonic plasmatocyte differentiation", "d": ["The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1901662", "l": "quinone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of quinone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051016", "l": "barbed-end actin filament capping", "d": ["The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904877", "l": "positive regulation of DNA ligase activity", "d": ["Any process that activates or increases the frequency, rate or extent of DNA ligase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.509418971541265", "identifiers": [{"i": "GO:0022407", "l": "regulation of cell-cell adhesion", "d": ["Any process that modulates the frequency, rate or extent of attachment of a cell to another cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.967140482697559", "identifiers": [{"i": "GO:0048193", "l": "Golgi vesicle transport", "d": ["The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.367421731069243", "identifiers": [{"i": "GO:0015812", "l": "gamma-aminobutyric acid transport", "d": ["The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031991", "l": "regulation of actomyosin contractile ring contraction", "d": ["Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis that takes place as part of a cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007317", "l": "regulation of pole plasm oskar mRNA localization", "d": ["Any process that modulates the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051497", "l": "negative regulation of stress fiber assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1990845", "l": "adaptive thermogenesis", "d": ["The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034197", "l": "triglyceride transport", "d": ["The directed movement of triglyceride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0051260", "l": "protein homooligomerization", "d": ["The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048924", "l": "posterior lateral line neuromast mantle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast mantle cell. (N.B. This may be development of neuromast mantle cell type or a set of cells of neuromast mantle cell type. This will involve the change of a cell or set of cells from one cell identity to another). Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.08946168400751", "identifiers": [{"i": "GO:0045321", "l": "leukocyte activation", "d": ["A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060214", "l": "endocardium formation", "d": ["Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0001890", "l": "placenta development", "d": ["The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903521", "l": "positive regulation of mammary gland involution", "d": ["Any process that activates or increases the frequency, rate or extent of mammary gland involution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.598265520774746", "identifiers": [{"i": "GO:0009566", "l": "fertilization", "d": ["The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060862", "l": "negative regulation of floral organ abscission", "d": ["Any process that decreases the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000390", "l": "spliceosomal complex disassembly", "d": ["Disassembly of a spliceosomal complex with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901431", "l": "regulation of response to cycloalkane", "d": ["Any process that modulates the frequency, rate or extent of response to cycloalkane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052865", "l": "1-deoxy-D-xylulose 5-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042865", "l": "pyochelin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051942", "l": "negative regulation of amino acid uptake involved in synaptic transmission", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043521", "l": "regulation of myosin II filament disassembly", "d": ["Any process that modulates the frequency, rate or extent of the disassembly of a bipolar filament composed of myosin II molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051619", "l": "inhibition of histamine uptake", "d": ["Any process that prevents the activation of the directed movement of histamine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045578", "l": "negative regulation of B cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046315", "l": "phosphocreatine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0045926", "l": "negative regulation of growth", "d": ["Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048400", "l": "positive regulation of intermediate mesodermal cell fate specification", "d": ["Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.871876592857262", "identifiers": [{"i": "GO:0048707", "l": "instar larval or pupal morphogenesis", "d": ["The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903397", "l": "positive regulation of secondary cell septum biogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of secondary cell septum biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070899", "l": "mitochondrial tRNA wobble uridine modification", "d": ["The process in which a uridine in position 34 of a mitochondrial tRNA is post-transcriptionally modified."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0042634", "l": "regulation of hair cycle", "d": ["Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.117739917690763", "identifiers": [{"i": "GO:0051321", "l": "meiotic cell cycle", "d": ["Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044080", "l": "modulation by symbiont of host cGMP-mediated signal transduction", "d": ["Any process in which a symbiont organism modulates the rate, frequency or extent of cGMP-mediated signaling in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0030032", "l": "lamellipodium assembly", "d": ["Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000349", "l": "negative regulation of CD40 signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the CD40 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035753", "l": "maintenance of DNA trinucleotide repeats", "d": ["Any process involved in sustaining the fidelity and copy number of DNA trinucleotide repeats. DNA trinucleotide repeats are naturally occurring runs of three base-pairs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904557", "l": "L-alanine transmembrane transport", "d": ["The directed movement of L-alanine across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.921291834945805", "identifiers": [{"i": "GO:0007631", "l": "feeding behavior", "d": ["Behavior associated with the intake of food."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903090", "l": "pyridoxal transmembrane transport", "d": ["The process in which pyridoxal is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003393", "l": "neuron migration involved in retrograde extension", "d": ["The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072093", "l": "metanephric renal vesicle formation", "d": ["The developmental process pertaining to the initial formation of the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014711", "l": "regulation of branchiomeric skeletal muscle development", "d": ["Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0090368", "l": "regulation of ornithine metabolic process", "d": ["Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010197", "l": "polar nucleus fusion", "d": ["The merging of the polar nuclei, the two nuclei contained within the same cell that are created from the mitotic division of the megaspore during angiosperm reproduction. Polar nuclear fusion takes place in the ovule, forming in the fusion nucleus and giving rise to the endosperm when fertilized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.543898531459924", "identifiers": [{"i": "GO:0050905", "l": "neuromuscular process", "d": ["Any process pertaining to the functions of the nervous and muscular systems of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903610", "l": "regulation of calcium-dependent ATPase activity", "d": ["Any process that modulates the frequency, rate or extent of calcium-dependent ATPase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099592", "l": "endocytosed synaptic vesicle processing via endosome", "d": ["The process in which endocytosed synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072152", "l": "glomerular mesangial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular mesangial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046804", "l": "peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide", "d": ["The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide (3-methyl-L-lanthionine sulfoxide), as found in the antibiotic actagardine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0010507", "l": "negative regulation of autophagy", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035477", "l": "regulation of angioblast cell migration involved in selective angioblast sprouting", "d": ["Any process that modulates the frequency, rate or extent of angioblast cell migration involved in selective angioblast sprouting."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140642", "l": "meiotic spindle formation (spindle phase two)", "d": ["The spindle organization process in which the spindle is maintained at a constant length during meiotic metaphase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900189", "l": "positive regulation of cell adhesion involved in single-species biofilm formation", "d": ["Any process that activates or increases the frequency, rate or extent of cell adhesion involved in single-species biofilm formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0010960", "l": "magnesium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046265", "l": "thiocyanate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of thiocyanate, any anion of thiocyanic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009912", "l": "auditory receptor cell fate commitment", "d": ["The process in which the cellular identity of auditory hair cells is acquired and determined."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052075", "l": "positive regulation by symbiont of host jasmonic acid-mediated defense response", "d": ["Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0046546", "l": "development of primary male sexual characteristics", "d": ["The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160027", "l": "egg deposition", "d": ["The multicellular organismal reproductive process that results in the movement of an egg from within an organism into the external environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0045913", "l": "positive regulation of carbohydrate metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097738", "l": "substrate mycelium formation", "d": ["The process by which, in some fungal species, hyphae grow as a network of invasive thread-like filaments formed from chains of attached cells within a solid or semi-solid substrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032455", "l": "nerve growth factor processing", "d": ["The generation of a mature nerve growth factor (NGF) by proteolysis of a precursor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0051510", "l": "regulation of unidimensional cell growth", "d": ["Any process that modulates the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:1903510", "l": "mucopolysaccharide metabolic process", "d": ["The chemical reactions and pathways involving mucopolysaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0085029", "l": "extracellular matrix assembly", "d": ["The aggregation, arrangement and bonding together of the extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015673", "l": "silver ion transport", "d": ["The directed movement of silver (Ag) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046132", "l": "pyrimidine ribonucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033542", "l": "fatty acid beta-oxidation, unsaturated, even number", "d": ["A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106299", "l": "resolution phase response", "d": ["An active host response phase of acute inflammation driven by specialized pro-resolving mediators (SPMs) and signaling pathways, enabling timely tissue regeneration and return of function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000304", "l": "response to singlet oxygen", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033532", "l": "stachyose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032677", "l": "regulation of interleukin-8 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-8 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090425", "l": "acinar cell differentiation", "d": ["The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0035794", "l": "positive regulation of mitochondrial membrane permeability", "d": ["Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019449", "l": "L-cysteine catabolic process to hypotaurine", "d": ["The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including hypotaurine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003316", "l": "establishment of myocardial progenitor cell apical/basal polarity", "d": ["The specification and formation of the apicobasal polarity of an myocardial progenitor cell that contributes to the formation of the heart rudiment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071660", "l": "positive regulation of IP-10 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of IP-10."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.760368348201226", "identifiers": [{"i": "GO:0009584", "l": "detection of visible light", "d": ["The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021847", "l": "ventricular zone neuroblast division", "d": ["The proliferation of neuroblasts in the ventricular zone of the cerebral cortex. The neuronal progenitors of these cells will migrate radially."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140872", "l": "viridicatumtoxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of viridicatumtoxin, a tetracycline-like fungal meroterpenoid with a unique, fused spirobicyclic ring system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045591", "l": "positive regulation of regulatory T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060946", "l": "cardiac blood vessel endothelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904135", "l": "positive regulation of convergent extension involved in rhombomere morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033519", "l": "phytyl diphosphate metabolic process", "d": ["The chemical reactions and pathways involving phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090318", "l": "regulation of chylomicron remodeling", "d": ["Any process that modulates the rate, frequency, or extent of chylomicron remodeling. Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901115", "l": "erythromycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of erythromycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046599", "l": "regulation of centriole replication", "d": ["Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034983", "l": "peptidyl-lysine deacetylation", "d": ["The removal of an acetyl group from an acetylated lysine residue in a peptide or protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060363", "l": "cranial suture morphogenesis", "d": ["The process in which any suture between cranial bones is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0050433", "l": "regulation of catecholamine secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of catecholamines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062143", "l": "L-propargylglycine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-propargylglycine (Pra). L-propargylglycine is an antibiotic produced by Streptomyces bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097178", "l": "ruffle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.316418070386277", "identifiers": [{"i": "GO:0045580", "l": "regulation of T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902127", "l": "(-)-lariciresinol metabolic process", "d": ["The chemical reactions and pathways involving (-)-lariciresinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019650", "l": "glycolytic fermentation to butanediol", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into butanediol; effected by some members of the Enterobacteriaceae, e.g. Enterobacter, Erwinia, Klebsiella, and Serratia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014064", "l": "positive regulation of serotonin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0006071", "l": "glycerol metabolic process", "d": ["The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010080", "l": "regulation of floral meristem growth", "d": ["Any process involved in maintaining the size and shape of a floral meristem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.062476272212777", "identifiers": [{"i": "GO:0007595", "l": "lactation", "d": ["The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0043562", "l": "cellular response to nitrogen levels", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of inorganic nitrogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:2000904", "l": "regulation of starch metabolic process", "d": ["Any process that modulates the frequency, rate or extent of starch metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019678", "l": "propionate metabolic process, methylmalonyl pathway", "d": ["The chemical reactions and pathways involving propionate that occur in the methylmalonyl pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0008618", "l": "7-methylguanosine metabolic process", "d": ["The chemical reactions and pathways involving 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.152542716964341", "identifiers": [{"i": "GO:1901617", "l": "organic hydroxy compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of organic hydroxy compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900882", "l": "17-methylnonadec-1-ene metabolic process", "d": ["The chemical reactions and pathways involving 17-methylnonadec-1-ene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080027", "l": "response to herbivore", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a herbivore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0043093", "l": "FtsZ-dependent cytokinesis", "d": ["A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903042", "l": "negative regulation of chondrocyte hypertrophy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071528", "l": "tRNA re-export from nucleus", "d": ["The directed movement from the nucleus to the cytoplasm of a tRNA that was previously exported to the cytoplasm and then imported back into the nucleus. The processes of primary tRNA export and secondary export (re-export) can be distinguished because in organisms in which tRNA splicing occurs in the cytoplasm, the export of a mature tRNA must occur by re-export."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060552", "l": "positive regulation of fructose 1,6-bisphosphate metabolic process", "d": ["Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003066", "l": "positive regulation of heart rate by norepinephrine", "d": ["The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061869", "l": "regulation of hepatic stellate cell migration", "d": ["Any process that modulates the frequency, rate or extent of hepatic stellate cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090506", "l": "axillary shoot meristem initiation", "d": ["A developmental process that results in the initiation of an axillary shoot meristem. An axillary shoot meristem is a shoot meristem formed in the axil of a leaf."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009630", "l": "gravitropism", "d": ["The orientation of plant parts under the stimulation of gravity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904802", "l": "RITS complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a RITS complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019280", "l": "L-methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine", "d": ["The chemical reactions and pathways resulting in the formation of methionine from other compounds, including homoserine, via the intermediates O-acetyl-L-homoserine and cystathionine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.987832356016085", "identifiers": [{"i": "GO:0050432", "l": "catecholamine secretion", "d": ["The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072123", "l": "intraglomerular mesangial cell proliferation", "d": ["The multiplication or reproduction of intraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0031102", "l": "neuron projection regeneration", "d": ["The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0002474", "l": "antigen processing and presentation of peptide antigen via MHC class I", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046163", "l": "heme C catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of heme C, a derivative of heme found in cytochromes c, b4, and f."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904851", "l": "positive regulation of establishment of protein localization to telomere", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of protein localization to telomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000078", "l": "positive regulation of type B pancreatic cell development", "d": ["Any process that activates or increases the frequency, rate or extent of pancreatic B cell development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033638", "l": "modulation by symbiont of host heat acclimation", "d": ["Any process in which an organism modulates the host's tolerance to high temperatures, above the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002487", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class I via endolysosomal pathway", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in an endolysosome. Class I here refers to classical class I molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903060", "l": "negative regulation of protein lipidation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein lipidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021616", "l": "glossopharyngeal nerve formation", "d": ["The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048811", "l": "male analia morphogenesis", "d": ["The process in which the anatomical structures of the analia of the male are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904182", "l": "regulation of pyruvate dehydrogenase activity", "d": ["Any process that modulates the frequency, rate or extent of pyruvate dehydrogenase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903192", "l": "sesquarterpene metabolic process", "d": ["The chemical reactions and pathways involving sesquarterpene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0045862", "l": "positive regulation of proteolysis", "d": ["Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033350", "l": "apiose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903714", "l": "isoleucine transmembrane transport", "d": ["The directed movement of isoleucine across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903832", "l": "regulation of cellular response to amino acid starvation", "d": ["Any process that modulates the frequency, rate or extent of cellular response to amino acid starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0006089", "l": "lactate metabolic process", "d": ["The chemical reactions and pathways involving lactate, the anion of lactic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032687", "l": "negative regulation of interferon-alpha production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051462", "l": "regulation of cortisol secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of cortisol from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003275", "l": "apoptotic process involved in outflow tract morphogenesis", "d": ["Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071432", "l": "peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion", "d": ["The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of conjugation with cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061071", "l": "urethra epithelium development", "d": ["The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0003419", "l": "growth plate cartilage chondrocyte proliferation", "d": ["The multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905321", "l": "negative regulation of mesenchymal stem cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0051056", "l": "regulation of small GTPase mediated signal transduction", "d": ["Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001060", "l": "D-glycero-D-manno-heptose 7-phosphate metabolic process", "d": ["The chemical reactions and pathways involving a D-glycero-D-manno-heptose 7-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1905632", "l": "protein localization to euchromatin", "d": ["A process in which a protein is transported to, or maintained in, a location within an euchromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902796", "l": "regulation of snoRNA processing", "d": ["Any process that modulates the frequency, rate or extent of snoRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0072127", "l": "renal capsule development", "d": ["The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019619", "l": "3,4-dihydroxybenzoate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3,4-dihydroxybenzoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0060638", "l": "mesenchymal-epithelial cell signaling", "d": ["Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.509418971541265", "identifiers": [{"i": "GO:0006401", "l": "RNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901452", "l": "negative regulation of response to benzene", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to benzene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0030641", "l": "regulation of cellular pH", "d": ["Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048579", "l": "negative regulation of long-day photoperiodism, flowering", "d": ["Any process that stops, prevents or reduces long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045046", "l": "protein import into peroxisome membrane", "d": ["The targeting of proteins into the peroxisomal membrane. The process is not well understood, but both signals and mechanism differ from those involved in peroxisomal matrix protein import."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0019299", "l": "rhamnose metabolic process", "d": ["The chemical reactions and pathways involving rhamnose, the hexose 6-deoxy-L-mannose. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035696", "l": "monocyte extravasation", "d": ["The migration of a monocyte from the blood vessels into the surrounding tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044208", "l": "'de novo' AMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070177", "l": "contractile vacuole discharge", "d": ["The regulated release of water from a contractile vacuole to the outside of a cell by fusion of the contractile vacuole membrane with the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.879406879579491", "identifiers": [{"i": "GO:0062197", "l": "cellular response to chemical stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106428", "l": "positive regulation of kainate selective glutamate receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048441", "l": "petal development", "d": ["The process whose specific outcome is the progression of the petal over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000551", "l": "regulation of T-helper 2 cell cytokine production", "d": ["Any process that modulates the frequency, rate or extent of T-helper 2 cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.330951936344348", "identifiers": [{"i": "GO:0006473", "l": "protein acetylation", "d": ["The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060592", "l": "mammary gland formation", "d": ["The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1905024", "l": "regulation of membrane repolarization during ventricular cardiac muscle cell action potential", "d": ["Any process that modulates the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090213", "l": "regulation of radial pattern formation", "d": ["Any process that modulates the rate, frequency or extent of radial pattern formation, the regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002043", "l": "blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "d": ["The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population contributing to sprouting angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001986", "l": "negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure", "d": ["Any process that decreases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the baroreceptor response to increased blood pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905390", "l": "cellular response to leukotriene B4", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046371", "l": "dTDP-mannose metabolic process", "d": ["The chemical reactions and pathways involving dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:1904063", "l": "negative regulation of cation transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0060456", "l": "positive regulation of digestive system process", "d": ["Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046778", "l": "modification by virus of host mRNA processing", "d": ["Any viral process that interferes with the processing of mRNA in the host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0010212", "l": "response to ionizing radiation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072143", "l": "mesangial cell development", "d": ["The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990960", "l": "basophil homeostasis", "d": ["The process of regulating the proliferation and elimination of basophils such that the total number of basophils within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1904251", "l": "regulation of bile acid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of bile acid metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0045056", "l": "transcytosis", "d": ["The directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0030433", "l": "ubiquitin-dependent ERAD pathway", "d": ["The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010779", "l": "meiotic DNA repair synthesis involved in meiotic gene conversion", "d": ["The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051190", "l": "prosthetic group catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905778", "l": "negative regulation of exonuclease activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of exonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905362", "l": "negative regulation of endosomal vesicle fusion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endosomal vesicle fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:2000107", "l": "negative regulation of leukocyte apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0061180", "l": "mammary gland epithelium development", "d": ["The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0042088", "l": "T-helper 1 type immune response", "d": ["An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902079", "l": "D-valine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-valine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.675373588411375", "identifiers": [{"i": "GO:0009743", "l": "response to carbohydrate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021990", "l": "neural plate formation", "d": ["The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099610", "l": "action potential initiation", "d": ["The initiating cycle of an action potential. In vertebrate neurons this typically occurs at an axon hillock. Not all initiated axon potentials propagate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018057", "l": "peptidyl-lysine oxidation", "d": ["The oxidation of the terminal amino-methylene groups of peptidyl-L-lysine or peptidyl-5-hydroxy-L-lysine to aldehyde groups to form allysine or hydroxyallysine residues, respectively; these are intermediates in the formation of covalent cross-links between adjacent polypeptide chains in proteins such as collagens."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006055", "l": "CMP-N-acetylneuraminate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0046693", "l": "sperm storage", "d": ["The retention of sperm by a female following mating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0071472", "l": "cellular response to salt stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0010766", "l": "negative regulation of sodium ion transport", "d": ["Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0060324", "l": "face development", "d": ["The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0051311", "l": "meiotic metaphase plate congression", "d": ["The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140039", "l": "cell-cell adhesion in response to extracellular stimulus", "d": ["The attachment of one cell to another cell via adhesion molecules as a result of an extracellular stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044492", "l": "envenomation resulting in modulation of voltage-gated sodium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated sodium channel in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046668", "l": "regulation of retinal cell programmed cell death", "d": ["Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035562", "l": "negative regulation of chromatin binding", "d": ["Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901066", "l": "syringal lignin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of syringal lignin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009761", "l": "CAM photosynthesis", "d": ["The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) to make malic acid. The malic acid is then passed into the vacuole where it is stored until daylight, when it is shuttled back out to be used as a substrate in the light reaction of photosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071406", "l": "cellular response to methylmercury", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0009187", "l": "cyclic nucleotide metabolic process", "d": ["The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0006688", "l": "glycosphingolipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "37.205847785672724", "identifiers": [{"i": "GO:0001838", "l": "embryonic epithelial tube formation", "d": ["The morphogenesis of an embryonic epithelium into a tube-shaped structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000061", "l": "regulation of ureter smooth muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902571", "l": "regulation of serine-type peptidase activity", "d": ["Any process that modulates the frequency, rate or extent of serine-type peptidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044375", "l": "regulation of peroxisome size", "d": ["Any process that modulates the volume of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060970", "l": "embryonic heart tube dorsal/ventral pattern formation", "d": ["The regionalization process in which the areas along the dorsal/ventral axis of the embryonic heart tube are established. This process will determine the patterns of cell differentiation along the axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035747", "l": "natural killer cell chemotaxis", "d": ["The directed movement of a natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062176", "l": "R-loop processing", "d": ["A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007058", "l": "spindle assembly involved in female meiosis II", "d": ["The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis II of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0060463", "l": "lung lobe morphogenesis", "d": ["The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032008", "l": "positive regulation of TOR signaling", "d": ["Any process that activates or increases the frequency, rate or extent of TOR signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905593", "l": "positive regulation of optical nerve axon regeneration", "d": ["Any process that activates or increases the frequency, rate or extent of optical nerve axon regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0061842", "l": "microtubule organizing center localization", "d": ["Any process in which the microtubule organizing center is transported to, and/or maintained in, a specific location within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:1901655", "l": "cellular response to ketone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048930", "l": "glial cell migration in posterior lateral line nerve", "d": ["The movement of a glial cell along the axons in the posterior lateral line nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0071715", "l": "icosanoid transport", "d": ["The directed movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072766", "l": "centromere clustering at the mitotic interphase nuclear envelope", "d": ["The process in which chromatin, or kinetochores are anchored to the nuclear envelope. This process involves the microtubule cytoskeleton, and nuclear tethering factors and is responsible for the Rabl-like configuration of chromosomes in the interphase nuclei."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.659246641645865", "identifiers": [{"i": "GO:0030036", "l": "actin cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0046320", "l": "regulation of fatty acid oxidation", "d": ["Any process that modulates the frequency, rate or extent of fatty acid oxidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902597", "l": "positive regulation of DNA replication origin binding", "d": ["Any process that activates or increases the frequency, rate or extent of DNA replication origin binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904318", "l": "regulation of smooth muscle contraction involved in micturition", "d": ["Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021538", "l": "epithalamus development", "d": ["The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000288", "l": "positive regulation of myoblast proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of myoblast proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003429", "l": "growth plate cartilage chondrocyte morphogenesis", "d": ["The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090222", "l": "centrosome-templated microtubule nucleation", "d": ["The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from the centrosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0035220", "l": "wing disc development", "d": ["Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070481", "l": "nuclear-transcribed mRNA catabolic process, non-stop decay", "d": ["The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that is lacking a stop codon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140971", "l": "regulation of AIM2 inflammasome complex assembly", "d": ["Any process that modulates the frequency, rate or extent of AIM2 inflammasome complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0008592", "l": "regulation of Toll signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the Tl signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071930", "l": "negative regulation of transcription involved in G1/S transition of mitotic cell cycle", "d": ["Any process that stop, prevents or decreases transcription as part of the G1/S transition of the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048506", "l": "regulation of timing of meristematic phase transition", "d": ["Any process that modulates the rate, frequency or extent of a change in identity of a meristem at a characteristic predetermined time point."]}]}
{"type": "biolink:BiologicalProcess", "ic": "37.224497020821836", "identifiers": [{"i": "GO:0001841", "l": "neural tube formation", "d": ["The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035946", "l": "mitochondrial mRNA surveillance", "d": ["The set of processes involved in identifying and degrading messenger RNA (mRNA) within the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900006", "l": "positive regulation of dendrite development", "d": ["Any process that activates or increases the frequency, rate or extent of dendrite development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097167", "l": "circadian regulation of translation", "d": ["Any process that modulates the frequency, rate or extent of mRNA translation with a regularity of approximately 24 hours."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905847", "l": "negative regulation of cellular response to oxidopamine", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidopamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:1902224", "l": "ketone body metabolic process", "d": ["The chemical reactions and pathways involving ketone body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002623", "l": "negative regulation of B cell antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0031338", "l": "regulation of vesicle fusion", "d": ["Any process that modulates the frequency, rate or extent of vesicle fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036032", "l": "neural crest cell delamination", "d": ["The negative regulation of cell adhesion process in which a neural crest cell physically separates from the rest of the neural tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905943", "l": "negative regulation of formation of growth cone in injured axon", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of formation of growth cone in injured axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033325", "l": "choline biosynthetic process via phosphoryl-ethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate phosphoryl-ethanolamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010690", "l": "negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress", "d": ["Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a disturbance in organismal or cellular homeostasis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900988", "l": "ajmaline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ajmaline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0006359", "l": "regulation of transcription by RNA polymerase III", "d": ["Any process that modulates the frequency, rate or extent of transcription mediated by RNA ploymerase III."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046307", "l": "Z-phenylacetaldoxime biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0021533", "l": "cell differentiation in hindbrain", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000991", "l": "regulation of galactomannan catabolic process", "d": ["Any process that modulates the frequency, rate or extent of galactomannan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0002715", "l": "regulation of natural killer cell mediated immunity", "d": ["Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.330199557084356", "identifiers": [{"i": "GO:0006400", "l": "tRNA modification", "d": ["The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904421", "l": "response to D-galactosamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031632", "l": "positive regulation of synaptic vesicle fusion to presynaptic active zone membrane", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0032640", "l": "tumor necrosis factor production", "d": ["The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097288", "l": "7-cyano-7-deazaguanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032424", "l": "negative regulation of mismatch repair", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mismatch repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0045745", "l": "positive regulation of G protein-coupled receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904154", "l": "positive regulation of retrograde protein transport, ER to cytosol", "d": ["Any process that activates or increases the frequency, rate or extent of retrograde protein transport, ER to cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035495", "l": "regulation of SNARE complex disassembly", "d": ["Any process that modulates the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060940", "l": "epithelial to mesenchymal transition involved in cardiac fibroblast development", "d": ["A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905823", "l": "negative regulation of mitotic sister chromatid arm separation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid arm separation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000015", "l": "regulation of determination of dorsal identity", "d": ["Any process that modulates the frequency, rate or extent of determination of dorsal identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042914", "l": "colicin transport", "d": ["The directed movement of a colicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018926", "l": "methanesulfonic acid metabolic process", "d": ["The chemical reactions and pathways involving methanesulfonic acid, a strong acid produced by the oxidation of dimethyl sulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1904036", "l": "negative regulation of epithelial cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043215", "l": "daunorubicin transport", "d": ["The directed movement of daunorubicin, an anthracycline antibiotic produced by Streptomyces coeruleorubidus or S. peucetius and used as an antineoplastic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0071542", "l": "dopaminergic neuron differentiation", "d": ["The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071412", "l": "cellular response to genistein", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0045981", "l": "positive regulation of nucleotide metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072723", "l": "cellular response to amitrole", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902691", "l": "respiratory basal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a respiratory basal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060490", "l": "lateral sprouting involved in lung morphogenesis", "d": ["The process in which a branch forms along the side of the lung epithelial tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043442", "l": "acetoacetic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002533", "l": "lysosomal enzyme secretion involved in inflammatory response", "d": ["The regulated release of lysosomal enzymes by a cell as part of an inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002628", "l": "regulation of proteolysis associated with antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034077", "l": "butanediol metabolic process", "d": ["The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002559", "l": "type I hypersensitivity mediated by basophils", "d": ["An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035024", "l": "negative regulation of Rho protein signal transduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000160", "l": "negative regulation of planar cell polarity pathway involved in heart morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1903666", "l": "positive regulation of asexual reproduction", "d": ["Any process that activates or increases the frequency, rate or extent of asexual reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904114", "l": "positive regulation of muscle filament sliding", "d": ["Any process that activates or increases the frequency, rate or extent of muscle filament sliding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016319", "l": "mushroom body development", "d": ["The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0110113", "l": "positive regulation of lipid transporter activity", "d": ["Any process that increases the frequency, rate, or extent of lipid transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900364", "l": "negative regulation of mRNA polyadenylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mRNA polyadenylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035125", "l": "embryonic anal fin morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the embryonic anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019315", "l": "D-allose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090547", "l": "response to low humidity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of low humidity stimulus, reduced moisture in the atmosphere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006719", "l": "juvenile hormone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030709", "l": "border follicle cell delamination", "d": ["The delamination process that results in the splitting off of border cells from the anterior epithelium, prior to border cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150144", "l": "negative regulation of CD80 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD80 biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006973", "l": "intracellular accumulation of glycerol", "d": ["The accumulation of glycerol within a cell, for example by increased glycerol biosynthesis combined with decreased permeability of the cell membrane to glycerol, in response to the detection of a hyperosmotic environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072092", "l": "ureteric bud invasion", "d": ["The process in which the ureteric bud grows along its axis and contributes to the formation of the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0046390", "l": "ribose phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904156", "l": "DN3 thymocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a DN3 thymocyte. A DN3 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25+."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008583", "l": "mystery cell differentiation", "d": ["The process in which an undifferentiated cell acquires the features of a mystery cell. The mystery cells are a precluster of cells that emerge from the compound eye morphogenetic furrow, normally positioned between R3 and R4. They then disappear into the surrounding pool of undifferentiated cells and have no known fate in the mature ommatidium. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900076", "l": "regulation of cellular response to insulin stimulus", "d": ["Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002138", "l": "retinoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the biosynthesis of retinoic acid, one of the three components that makes up vitamin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030391", "l": "fructosamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0039674", "l": "exit of virus from host cell nucleus", "d": ["The directed movement of the viral genome or a viral particle out of the host cell nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900741", "l": "regulation of filamentous growth of a population of unicellular organisms in response to pH", "d": ["Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.675373588411375", "identifiers": [{"i": "GO:0002821", "l": "positive regulation of adaptive immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of an adaptive immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001197", "l": "basement membrane assembly involved in embryonic body morphogenesis", "d": ["Any basement membrane assembly that is involved in embryonic body morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0002455", "l": "humoral immune response mediated by circulating immunoglobulin", "d": ["An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1904809", "l": "regulation of dense core granule transport", "d": ["Any process that modulates the frequency, rate or extent of dense core granule transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140821", "l": "UDP-beta-L-arabinofuranose import into Golgi lumen", "d": ["The directed movement of UDP-beta-L-arabinofuranose from the cytosol to the Golgi apparatus of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090228", "l": "positive regulation of red or far-red light signaling pathway", "d": ["Any process that increases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1902633", "l": "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:0042558", "l": "pteridine-containing compound metabolic process", "d": ["The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0070914", "l": "UV-damage excision repair", "d": ["A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033513", "l": "L-lysine catabolic process to acetyl-CoA via 5-aminopentanamide", "d": ["The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate 5-aminopentanamide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019630", "l": "quinate metabolic process", "d": ["The chemical reactions and pathways involving quinate, the anion of quinic acid. The acid occurs commonly in plants, either free or as esters, and is used as a medicine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2000387", "l": "regulation of antral ovarian follicle growth", "d": ["Any process that modulates the frequency, rate or extent of antral ovarian follicle growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0006353", "l": "DNA-templated transcription termination", "d": ["The completion of transcription: the RNA polymerase pauses, the RNA-DNA hybrid dissociates, followed by the release of the RNA polymerase from its DNA template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002603", "l": "positive regulation of antigen processing and presentation of polysaccharide antigen via MHC class II", "d": ["Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:1901679", "l": "nucleotide transmembrane transport", "d": ["The directed movement of nucleotide across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010426", "l": "DNA methylation on cytosine within a CHH sequence", "d": ["The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within an asymmetric CHH sequence in a DNA molecule. H stands for an adenine, cytosine, or thymine nucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060022", "l": "hard palate development", "d": ["The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060063", "l": "Spemann organizer formation at the embryonic shield", "d": ["Formation of the specialized region of the embryonic shield of the embryo that acts as the main signaling center establishing the teleost body plan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000885", "l": "galactoglucomannan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a galactoglucomannan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1901421", "l": "positive regulation of response to alcohol", "d": ["Any process that activates or increases the frequency, rate or extent of response to alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035016", "l": "elongation of arista lateral", "d": ["The increase in length of the aristal laterals. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.235616146829116", "identifiers": [{"i": "GO:0061647", "l": "histone H3-K9 modification", "d": ["The modification of histone H3 at a lysine in position 9 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090669", "l": "telomerase RNA stabilization", "d": ["Prevention of degradation of telomerase RNA (TERC) molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0001570", "l": "vasculogenesis", "d": ["The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000513", "l": "positive regulation of granzyme A production", "d": ["Any process that activates or increases the frequency, rate or extent of granzyme A production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0046484", "l": "oxazole or thiazole metabolic process", "d": ["The chemical reactions and pathways involving oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000244", "l": "spliceosomal tri-snRNP complex assembly", "d": ["The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0032528", "l": "microvillus organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903898", "l": "negative regulation of PERK-mediated unfolded protein response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the PERK-mediated unfolded protein response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.551999999910333", "identifiers": [{"i": "GO:0043170", "l": "macromolecule metabolic process", "d": ["The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903116", "l": "positive regulation of actin filament-based movement", "d": ["Any process that activates or increases the frequency, rate or extent of actin filament-based movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035532", "l": "negative regulation of chemokine (C-C motif) ligand 6 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.594043123901756", "identifiers": [{"i": "GO:0016311", "l": "dephosphorylation", "d": ["The process of removing one or more phosphoric (ester or anhydride) residues from a molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990656", "l": "t-SNARE clustering", "d": ["The clustering process in which t-SNARES are localized to distinct domains in the cell membrane. t-SNAREs are cell surface proteins which are part of secretory microdomain assemblies."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140505", "l": "regulation of microlipophagy", "d": ["Any process that modulates the frequency, rate or extent of microlipophagy, the microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.910167345505712", "identifiers": [{"i": "GO:0034219", "l": "carbohydrate transmembrane transport", "d": ["The process in which a carbohydrate is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000373", "l": "Group II intron splicing", "d": ["The splicing of Group II introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group II introns and containing splice site consensus sequences, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions (mechanistically similar to those for splicing of nuclear mRNAs) initiated by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903869", "l": "negative regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044510", "l": "envenomation resulting in positive regulation of signal transduction in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of signal transduction in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090216", "l": "positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity", "d": ["Any process that increases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071414", "l": "cellular response to methotrexate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051121", "l": "hepoxilin metabolic process", "d": ["The chemical reactions and pathways involving hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106107", "l": "regulation of (R)-mevalonic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of (R)-mevalonic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051111", "l": "peptidyl-histidine adenylylation", "d": ["The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine) or peptidyl-3'-(phospho-5'-adenosine)-L-histidine (otherwise known as pi-AMP-histidine, pros-AMP-histidine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0080171", "l": "lytic vacuole organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0080147", "l": "root hair cell development", "d": ["The process whose specific outcome is the progression of a root hair cell over time, from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "50.030058490207793", "identifiers": [{"i": "GO:0001501", "l": "skeletal system development", "d": ["The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:2001259", "l": "positive regulation of cation channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of cation channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902157", "l": "regulation of response to G2 DNA damage checkpoint signaling", "d": ["Any process that modulates the frequency, rate or extent of response to G2 DNA damage checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018016", "l": "N-terminal peptidyl-proline dimethylation", "d": ["The methylation of the N-terminal proline of proteins to form the derivative N,N-dimethyl-L-proline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905487", "l": "negative regulation of anterior/posterior axon guidance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anterior/posterior axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:2000516", "l": "positive regulation of CD4-positive, alpha-beta T cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0042416", "l": "dopamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075297", "l": "negative regulation of ascospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0048461", "l": "flower structural organization", "d": ["The process that contributes to the act of creating the structural organization of the flower. This process pertains to the physical shaping of a rudimentary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008340", "l": "determination of adult lifespan", "d": ["The pathways that regulate the duration of the adult phase of the life-cycle of an animal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060745", "l": "mammary gland branching involved in pregnancy", "d": ["The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.527781272052167", "identifiers": [{"i": "GO:0018393", "l": "internal peptidyl-lysine acetylation", "d": ["The addition of an acetyl group to a non-terminal lysine residue in a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070889", "l": "platelet alpha granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet alpha granule. A platelet alpha granule is a secretory organelle found in blood platelets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018150", "l": "peptide cross-linking via 3-(3'-L-histidyl)-L-tyrosine", "d": ["The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3-(3'-L-histidyl)-L-tyrosine protein cross-link."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071246", "l": "cellular response to chlorate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0002890", "l": "negative regulation of immunoglobulin mediated immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901392", "l": "regulation of transforming growth factor beta1 activation", "d": ["Any process that modulates the frequency, rate or extent of transforming growth factor beta1 activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061108", "l": "seminal vesicle epithelium development", "d": ["The progression of the seminal vesicle epithelium over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:0051099", "l": "positive regulation of binding", "d": ["Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905027", "l": "regulation of membrane depolarization during AV node cell action potential", "d": ["Any process that modulates the frequency, rate or extent of membrane depolarization during AV node cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006653", "l": "1,2-diacyl-sn-glycero-3-phosphocholine metabolic process", "d": ["The chemical reactions and pathways involving any 1,2-diacyl-sn-glycero-3-phosphocholine, the compounds most commonly designated lecithin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900647", "l": "negative regulation of chanoclavine-I aldehyde biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0006094", "l": "gluconeogenesis", "d": ["The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903352", "l": "L-ornithine transmembrane transport", "d": ["The directed movement of L-ornithine across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034194", "l": "D-galactonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-galactonate, the anion of D-galactonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0050687", "l": "negative regulation of defense response to virus", "d": ["Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0033067", "l": "macrolide metabolic process", "d": ["The chemical reactions and pathways involving macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0009806", "l": "lignan metabolic process", "d": ["The chemical reactions and pathways involving lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035530", "l": "chemokine (C-C motif) ligand 6 production", "d": ["The appearance of chemokine (C-C motif) ligand 6 (CCL6) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033860", "l": "regulation of NAD(P)H oxidase activity", "d": ["Any process that modulates the activity of the enzyme NAD(P)H oxidase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.367421731069243", "identifiers": [{"i": "GO:0050776", "l": "regulation of immune response", "d": ["Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007407", "l": "neuroblast activation", "d": ["A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0072538", "l": "T-helper 17 type immune response", "d": ["An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0050990", "l": "N-terminal protein amino acid carbamoylation", "d": ["The carbamoylation of the N-terminal amino acid of proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002781", "l": "antifungal peptide production", "d": ["The synthesis or release of an antifungal peptide during an immune response, resulting in an increase in intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001981", "l": "baroreceptor detection of arterial stretch", "d": ["The series of events by which the change in diameter of an artery is detected and converted to a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0009851", "l": "auxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070372", "l": "regulation of ERK1 and ERK2 cascade", "d": ["Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071469", "l": "cellular response to alkaline pH", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901717", "l": "positive regulation of gamma-aminobutyric acid catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0035459", "l": "vesicle cargo loading", "d": ["The formation of a macromolecular complex between the coat proteins and proteins and/or lipoproteins that are going to be transported by a vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090721", "l": "primary adaptive immune response involving T cells and B cells", "d": ["An adaptive immune response mediated by naive T or B cells against an antigen not previously encountered by immune system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903743", "l": "negative regulation of anterograde synaptic vesicle transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anterograde synaptic vesicle transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039557", "l": "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity", "d": ["Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of IRF7 (interferon regulatory factor-7). IRF7 a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF7, which allows IRF7 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:1903020", "l": "positive regulation of glycoprotein metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990544", "l": "mitochondrial ATP transmembrane transport", "d": ["The process in which ATP is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018301", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon", "d": ["The incorporation of iron into an iron-sulfur cluster by tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001263", "l": "regulation of C-C chemokine binding", "d": ["Any process that modulates the frequency, rate or extent of C-C chemokine binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030185", "l": "nitric oxide transport", "d": ["The directed movement of nitric oxide, nitrogen monoxide, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0061371", "l": "determination of heart left/right asymmetry", "d": ["Determination of the asymmetric location of the heart with respect to the left and right halves of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000062", "l": "negative regulation of ureter smooth muscle cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045961", "l": "negative regulation of development, heterochronic", "d": ["Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and decreases the rate at which this time point is reached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0021814", "l": "cell motility involved in cerebral cortex radial glia guided migration", "d": ["The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042487", "l": "regulation of odontogenesis of dentin-containing tooth", "d": ["Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051862", "l": "translocation of molecules into symbiont", "d": ["The directed movement of molecule(s) produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045880", "l": "positive regulation of smoothened signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of smoothened signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099645", "l": "neurotransmitter receptor localization to postsynaptic specialization membrane", "d": ["A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0086015", "l": "SA node cell action potential", "d": ["An action potential that occurs in a sinoatrial node cardiac muscle cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051652", "l": "maintenance of chromosome location", "d": ["Any process in which a chromosome is maintained in a specific location within a cell and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905560", "l": "negative regulation of kinetochore assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of kinetochore assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0002891", "l": "positive regulation of immunoglobulin mediated immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002227", "l": "innate immune response in mucosa", "d": ["Any process of the innate immune response that takes place in the mucosal tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071767", "l": "mycolic acid metabolic process", "d": ["The chemical reactions and pathways involving mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032258", "l": "cytoplasm to vacuole transport by the Cvt pathway", "d": ["A cytoplasm to vacuole targeting pathway that uses machinery common with autophagy. The Cvt vesicle is formed when the receptor protein, Atg19, binds to the complexes of the target protein (aminopeptidase or alpha-mannosidase homododecamers), forming the Cvt complex. Atg11 binds to Atg9 and transports the Cvt complex to the pre-autophagosome (PAS). The phagophore membrane expands around the Cvt complex (excluding bulk cytoplasm) forming the Cvt vesicle. This pathway is mostly observed in yeast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0044360", "l": "modulation of voltage-gated potassium channel activity in another organism", "d": ["Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990515", "l": "3' transitive RNA interference", "d": ["An RNA interference where the silencing signal spreads 3' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "37.150712341524098", "identifiers": [{"i": "GO:0009792", "l": "embryo development ending in birth or egg hatching", "d": ["The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0040040", "l": "thermosensory behavior", "d": ["Behavior that is dependent upon the sensation of temperature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0071470", "l": "cellular response to osmotic stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990946", "l": "meiosis I/meiosis II transition", "d": ["The cell cycle process in which a cell progresses from meiosis I to meiosis II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090086", "l": "negative regulation of protein deubiquitination", "d": ["Any process that decreases the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002232", "l": "leukocyte chemotaxis involved in inflammatory response", "d": ["The movement of an immune cell in response to an external stimulus contributing to an inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034151", "l": "regulation of toll-like receptor 6 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 6 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009293", "l": "transduction", "d": ["A type of horizontal gene transfer in which genetic material is introduced into a cell mediated by a virus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090606", "l": "single-species surface biofilm formation", "d": ["A process in which microorganisms produce an extracellular matrix and form multicellular aggregates at an air-liquid interface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000002", "l": "negative regulation of DNA damage checkpoint", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a DNA damage checkpoint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006545", "l": "glycine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.83044649042801", "identifiers": [{"i": "GO:0050910", "l": "detection of mechanical stimulus involved in sensory perception of sound", "d": ["The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.062480095235458", "identifiers": [{"i": "GO:0042755", "l": "eating behavior", "d": ["The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070934", "l": "CRD-mediated mRNA stabilization", "d": ["An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060695", "l": "negative regulation of cholesterol transporter activity", "d": ["Any process that decreases the rate, frequency, or extent of cholesterol transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901461", "l": "negative regulation of response to formic acid", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to formic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001043", "l": "positive regulation of septum digestion after cytokinesis", "d": ["Any process that activates or increases the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0007288", "l": "sperm axoneme assembly", "d": ["The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071646", "l": "regulation of macrophage inflammatory protein-1 gamma production", "d": ["Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902062", "l": "betaine aldehyde catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of betaine aldehyde."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0034343", "l": "type III interferon production", "d": ["The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035545", "l": "determination of left/right asymmetry in nervous system", "d": ["The establishment of the nervous system with respect to the left and right halves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007228", "l": "positive regulation of hh target transcription factor activity", "d": ["Any process that increases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates, members of the Gli protein family are activated in this way. Activation of the Gli/Ci transcription factor is distinct from its stabilization, when proteolytic cleavage is inhibited."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061925", "l": "negative regulation of formation of radial glial scaffolds", "d": ["Any process that reduces the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043985", "l": "histone H4-R3 methylation", "d": ["The modification of histone H4 by addition of a methyl group to arginine at position 3 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032331", "l": "negative regulation of chondrocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0062125", "l": "regulation of mitochondrial gene expression", "d": ["Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901876", "l": "regulation of calcium ion binding", "d": ["Any process that modulates the frequency, rate or extent of calcium ion binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006142", "l": "regulation of pyrimidine nucleobase metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051290", "l": "protein heterotetramerization", "d": ["The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018102", "l": "peptidyl-arginine hydroxylation to peptidyl-4-hydroxy-L-arginine", "d": ["The hydroxylation of peptidyl-arginine to form peptidyl-4-hydroxy-L-arginine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904900", "l": "negative regulation of myosin II filament organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.706690997211318", "identifiers": [{"i": "GO:0099046", "l": "clearance of foreign intracellular nucleic acids", "d": ["A defense process that protects an organism from DNA or RNA from an invading organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110074", "l": "positive regulation of apical constriction involved in ventral furrow formation", "d": ["Any process that activates or increases the frequency, rate or extent of apical constriction involved in ventral furrow formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1903578", "l": "regulation of ATP metabolic process", "d": ["Any process that modulates the frequency, rate or extent of ATP metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0021985", "l": "neurohypophysis development", "d": ["The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903812", "l": "L-serine import across plasma membrane", "d": ["The directed movement of L-serine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070623", "l": "regulation of thiamine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035524", "l": "proline transmembrane transport", "d": ["The directed movement of proline, pyrrolidine-2-carboxylic acid, across a membrane by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0010921", "l": "regulation of phosphatase activity", "d": ["Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900029", "l": "positive regulation of ruffle assembly", "d": ["Any process that activates or increases the frequency, rate or extent of ruffle assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900445", "l": "positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus", "d": ["Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042297", "l": "vocal learning", "d": ["A behavioral process whose outcome is a relatively long-lasting behavioral change whereby an organism modifies innate vocalizations to imitate sounds produced by others."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0006277", "l": "DNA amplification", "d": ["The process in which the number of copies of a gene is increased in certain cells as extra copies of DNA are made in response to certain signals of cell development or of stress from the environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003286", "l": "atrial septum intermedium development", "d": ["The progression of the atrial septum intermedium over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905631", "l": "cellular response to glyceraldehyde", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904210", "l": "VCP-NPL4-UFD1 AAA ATPase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a VCP-NPL4-UFD1 AAA ATPase complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "37.727153865801462", "identifiers": [{"i": "GO:0019226", "l": "transmission of nerve impulse", "d": ["The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021816", "l": "extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration", "d": ["The rearrangements of the microtubule cytoskeleton that result in the extension of a leading process, where this process is involved in the movement of cells along radial glial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0019682", "l": "glyceraldehyde-3-phosphate metabolic process", "d": ["The chemical reactions and pathways involving glyceraldehyde-3-phosphate, an important intermediate in glycolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044256", "l": "protein digestion", "d": ["The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested proteins into components that may be easily absorbed and directed into metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021852", "l": "pyramidal neuron migration to cerebral cortex", "d": ["The migration of a pyramidal neuron precursor from the ventricular zone to the correct layer of the cerebral cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902840", "l": "positive regulation of nuclear migration along microtubule", "d": ["Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140290", "l": "peptidyl-serine ADP-deribosylation", "d": ["The removal of ADP-ribose from ADP-ribosylserine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051973", "l": "positive regulation of telomerase activity", "d": ["Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0072178", "l": "nephric duct morphogenesis", "d": ["The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.348726733271597", "identifiers": [{"i": "GO:0050881", "l": "musculoskeletal movement", "d": ["The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.868753869559903", "identifiers": [{"i": "GO:0007155", "l": "cell adhesion", "d": ["The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904583", "l": "response to polyamine macromolecule", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051967", "l": "negative regulation of synaptic transmission, glutamatergic", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090385", "l": "phagosome-lysosome fusion", "d": ["The creation of a phagolysosome from a phagosome and a lysosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048694", "l": "positive regulation of collateral sprouting of injured axon", "d": ["Any process that activates, maintains or increases the rate of collateral sprouting of an injured axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000019", "l": "negative regulation of male gonad development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0140049", "l": "regulation of endocardial cushion to mesenchymal transition", "d": ["Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1904396", "l": "regulation of neuromuscular junction development", "d": ["Any process that modulates the frequency, rate or extent of neuromuscular junction development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032431", "l": "activation of phospholipase A2 activity", "d": ["Any process that initiates the activity of the inactive enzyme phospholipase A2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0071708", "l": "immunoglobulin light chain V-J recombination", "d": ["The process in which immunoglobulin light chain V and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021809", "l": "neurotrophic factor signaling initiating cell movement, involved in cerebral cortex radial glia guided migration", "d": ["Signaling between members of the neurotrophin family and their receptors that result in the start of cell motility as a component of the process of cerebral cortex glial-mediated radial migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000056", "l": "regulation of Wnt signaling pathway involved in digestive tract morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0061684", "l": "chaperone-mediated autophagy", "d": ["The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900598", "l": "demethylkotanin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of demethylkotanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060653", "l": "epithelial cell differentiation involved in mammary gland cord morphogenesis", "d": ["The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901610", "l": "positive regulation of vesicle transport along microtubule", "d": ["Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905177", "l": "tracheary element differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a tracheary element."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010244", "l": "response to low fluence blue light stimulus by blue low-fluence system", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a low fluence blue light stimulus by the blue low-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue low-fluence system responds to blue light at or below 0.1 micromols/m2. In certain species excitation of the blue low fluence system induces the transcription of a number of nuclear and plastid coded genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014002", "l": "astrocyte development", "d": ["The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048136", "l": "male germ-line cyst formation", "d": ["Formation of a group of interconnected cells derived from a single male gonial founder cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0002387", "l": "immune response in gut-associated lymphoid tissue", "d": ["Immune response taking place in the gut-associated lymphoid tissue (GALT). GALT includes Peyer's patches, appendix, and solitary lymph nodules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904611", "l": "cellular response to 3,3',4,4',5-pentachlorobiphenyl", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0002579", "l": "positive regulation of antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048067", "l": "cuticle pigmentation", "d": ["Establishment of a pattern of pigment in the cuticle of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071047", "l": "polyadenylation-dependent mRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048143", "l": "astrocyte activation", "d": ["A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0043174", "l": "nucleoside salvage", "d": ["Any process which produces a nucleotide, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide), from derivatives of it without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900433", "l": "positive regulation of filamentous growth of a population of unicellular organisms in response to heat", "d": ["Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000691", "l": "negative regulation of cardiac muscle cell myoblast differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000684", "l": "negative regulation of cellular response to X-ray", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to X-ray."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044598", "l": "doxorubicin metabolic process", "d": ["The chemical reactions and pathways involving doxorubicin, an anthracycline antibiotic, used in cancer chemotherapy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0018377", "l": "protein myristoylation", "d": ["The covalent attachment of a myristoyl group to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018188", "l": "peptidyl-proline di-hydroxylation", "d": ["The modification of peptidyl-proline to form trans-2,3-cis-3,4-dihydroxy-L-proline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019060", "l": "intracellular transport of viral protein in host cell", "d": ["The directed movement of a viral protein within the host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902014", "l": "poly(glycerol phosphate) teichoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(glycerol phosphate) teichoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010762", "l": "regulation of fibroblast migration", "d": ["Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160076", "l": "negative regulation of non-canonical inflammasome complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of non-canonical inflammasome complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120011", "l": "intermembrane sterol transfer", "d": ["The transport of sterols between membranes in which a sterol molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.066601674840506", "identifiers": [{"i": "GO:0061458", "l": "reproductive system development", "d": ["The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071387", "l": "cellular response to cortisol stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018977", "l": "1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process", "d": ["The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0045806", "l": "negative regulation of endocytosis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019402", "l": "galactitol metabolic process", "d": ["The chemical reactions and pathways involving galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090255", "l": "cell proliferation involved in imaginal disc-derived wing morphogenesis", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0086046", "l": "membrane depolarization during SA node cell action potential", "d": ["The process in which SA node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045199", "l": "maintenance of epithelial cell apical/basal polarity", "d": ["The maintenance of the apicobasal polarity of an epithelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901087", "l": "benzylpenicillin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of benzylpenicillin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035199", "l": "salt aversion", "d": ["The specific avoidance actions or reactions of an organism in response to the perception of salt."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0032372", "l": "negative regulation of sterol transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904537", "l": "negative regulation of mitotic telomere tethering at nuclear periphery", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic telomere tethering at nuclear periphery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0006760", "l": "folic acid-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010896", "l": "regulation of triglyceride catabolic process", "d": ["Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903316", "l": "positive regulation of nitrogen cycle metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of nitrogen cycle metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003430", "l": "growth plate cartilage chondrocyte growth", "d": ["The growth of a growth plate cartilage chondrocyte, where growth contributes to the progression of the chondrocyte over time from one condition to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006713", "l": "glucocorticoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048631", "l": "regulation of skeletal muscle tissue growth", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0002654", "l": "positive regulation of tolerance induction dependent upon immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055111", "l": "ingression involved in gastrulation with mouth forming second", "d": ["The migration of individual cells into the embryo involved in deuterostomic gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0061492", "l": "asymmetric protein localization to old or new spindle pole body", "d": ["Any process in which a protein is transported to, or maintained to either the old or new spindle pole body resulting in its being distributed asymmetrically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021747", "l": "cochlear nucleus development", "d": ["The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000381", "l": "regulation of alternative mRNA splicing, via spliceosome", "d": ["Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0031061", "l": "negative regulation of histone methylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090013", "l": "regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation", "d": ["Any process that modulates the frequency, rate or extent of any TGF-beta receptor signaling pathway that contributes to the formation of the primitive streak."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990739", "l": "granulosa cell proliferation", "d": ["The multiplication or reproduction of granulosa cells, resulting in the expansion of the granulosa cells population. A granulosa cell is a supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030026", "l": "intracellular manganese ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of manganese ions within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032848", "l": "negative regulation of cellular pH reduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a process that reduces the internal pH of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0080144", "l": "intracellular amino acid homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of amino acids within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0010718", "l": "positive regulation of epithelial to mesenchymal transition", "d": ["Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900204", "l": "apoptotic process involved in metanephric collecting duct development", "d": ["Any apoptotic process that is involved in metanephric collecting duct development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031918", "l": "positive regulation of synaptic metaplasticity", "d": ["A process that increases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.701131597012193", "identifiers": [{"i": "GO:0045184", "l": "establishment of protein localization", "d": ["The directed movement of a protein to a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900297", "l": "regulation of hexasaccharide transport", "d": ["Any process that modulates the frequency, rate or extent of hexasaccharide transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0106001", "l": "intestinal hexose absorption", "d": ["Uptake of hexoses, notably D-glucose, fructose, and galactose, into the blood by absorption from the small intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904404", "l": "response to formaldehyde", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051327", "l": "meiotic M phase", "d": ["A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902482", "l": "regulatory T cell apoptotic process", "d": ["Any apoptotic process in a regulatory T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061447", "l": "endocardial cushion cell fate specification", "d": ["The process involved in the specification of endocardial cushion cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035185", "l": "preblastoderm mitotic cell cycle", "d": ["The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. This is the first phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048376", "l": "positive regulation of lateral mesodermal cell fate determination", "d": ["Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0051031", "l": "tRNA transport", "d": ["The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033479", "l": "UDP-D-galacturonate metabolic process", "d": ["The chemical reactions and pathways involving UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048837", "l": "sorocarp sorus development", "d": ["The process whose specific outcome is the progression of the sorocarp sorus over time, from its formation to the mature structure. A sorocarp sorus is the spore containing structure of a sorocarp."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0010950", "l": "positive regulation of endopeptidase activity", "d": ["Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048621", "l": "post-embryonic digestive tract morphogenesis", "d": ["The process, occurring during the post-embryonic phase, by which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007621", "l": "negative regulation of female receptivity", "d": ["Any process that stops, prevents or reduces the receptiveness of a female to male advances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042211", "l": "dimethylsilanediol catabolic process", "d": ["The aerobic chemical reactions and pathways resulting in the breakdown of dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048853", "l": "forebrain morphogenesis", "d": ["The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050823", "l": "peptide antigen stabilization", "d": ["Any process involved in maintaining the structure and integrity of a peptide antigen and preventing it from being degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061158", "l": "3'-UTR-mediated mRNA destabilization", "d": ["An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070671", "l": "response to interleukin-12", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042426", "l": "choline catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048616", "l": "post-embryonic anterior midgut (ectodermal) morphogenesis", "d": ["The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the post-embryonic phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048164", "l": "distinct antral spaces stage", "d": ["The stage in oogenesis when the antral spaces become distinct and the first polar body forms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061192", "l": "negative regulation of vacuole fusion, non-autophagic", "d": ["Any process that decreases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106400", "l": "double-strand break repair via transcription-associated homologous recombination", "d": ["A mechanism of homologous recombination and DNA repair in which transcript RNA is used as a template for DSB repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904021", "l": "negative regulation of G protein-coupled receptor internalization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of G protein-coupled receptor internalization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002283", "l": "neutrophil activation involved in immune response", "d": ["The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1902415", "l": "regulation of mRNA binding", "d": ["Any process that modulates the frequency, rate or extent of mRNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009960", "l": "endosperm development", "d": ["The process whose specific outcome is the progression of the endosperm over time, from its formation to the mature structure. The endosperm is formed during fertilization and provides nutrients to the developing embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0021516", "l": "dorsal spinal cord development", "d": ["The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0042726", "l": "flavin-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000813", "l": "negative regulation of barbed-end actin filament capping", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of barbed-end actin filament capping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046642", "l": "negative regulation of alpha-beta T cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0034088", "l": "maintenance of mitotic sister chromatid cohesion", "d": ["The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0033374", "l": "protein localization to T cell secretory granule", "d": ["A process in which a protein is transported to, or maintained in, a location within a secretory granule in a T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006170", "l": "dAMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006603", "l": "phosphocreatine metabolic process", "d": ["The chemical reactions and pathways involving phosphocreatine, a phosphagen of creatine present in high concentration in striated muscle which is synthesized and broken down by creatine phosphokinase to buffer ATP concentration. It acts as an immediate energy reserve for muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.722653756574275", "identifiers": [{"i": "GO:0015837", "l": "amine transport", "d": ["The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0003228", "l": "atrial cardiac muscle tissue development", "d": ["The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904890", "l": "negative regulation of excitatory synapse assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140538", "l": "negative regulation of conjugation with zygote", "d": ["A process that prevents a zygote from fusing an additional cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900960", "l": "negative regulation of 17-methylnonadec-1-ene metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039677", "l": "exit of virus from host cell nucleus via nuclear envelope disassembly", "d": ["The directed movement of the viral genome or a viral particle out of the host cell nucleus that involves disruption of the nuclear membrane envelope by the virus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070596", "l": "(1->3)-alpha-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019622", "l": "3-(3-hydroxy)phenylpropionate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099019", "l": "maintenance of protein localization at growing cell tip", "d": ["Any process in which localization of a protein is maintained at the growing cell tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0100008", "l": "regulation of fever generation by prostaglandin biosynthetic process", "d": ["Any prostaglandin biosynthetic process process that regulates fever generation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033337", "l": "dorsal fin development", "d": ["The process whose specific outcome is the progression of the dorsal fin over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044809", "l": "chemokine (C-C motif) ligand 17 production", "d": ["The appearance of chemokine (C-C motif) ligand 17 (CCL17) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032533", "l": "regulation of follicle cell microvillus length", "d": ["A process that modulates the length of a microvillus on a follicle cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014879", "l": "detection of electrical stimulus involved in regulation of muscle adaptation", "d": ["The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0006714", "l": "sesquiterpenoid metabolic process", "d": ["The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905682", "l": "positive regulation of innate immunity memory response", "d": ["Any process that activates or increases the frequency, rate or extent of innate immunity memory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901002", "l": "positive regulation of response to salt stress", "d": ["Any process that activates or increases the frequency, rate or extent of response to salt stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905050", "l": "positive regulation of metallopeptidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of metallopeptidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.003741351937961", "identifiers": [{"i": "GO:2001233", "l": "regulation of apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0017008", "l": "protein-phycobiliviolin linkage", "d": ["The linkage of the chromophore phycobiliviolin to phycoerythrocyanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071651", "l": "positive regulation of chemokine (C-C motif) ligand 5 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045994", "l": "positive regulation of translational initiation by iron", "d": ["Any process involving iron that activates or increases the rate of translational initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.142364941642427", "identifiers": [{"i": "GO:0043934", "l": "sporulation", "d": ["The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035941", "l": "androstenedione secretion", "d": ["The regulated release of androstenedione (androst-4-ene-3,17-dione) into the circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039023", "l": "pronephric duct morphogenesis", "d": ["The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0017158", "l": "regulation of calcium ion-dependent exocytosis", "d": ["Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002530", "l": "regulation of systemic arterial blood pressure involved in acute-phase response", "d": ["Any process that modulates the force with which blood travels through the circulatory system that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042679", "l": "compound eye cone cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085001", "l": "formation of stylet for nutrient acquisition", "d": ["The assembly of a stylet, a hollow protrusible spear-like symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000685", "l": "positive regulation of cellular response to X-ray", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to X-ray."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140847", "l": "negative regulation of promoter clearance from RNA polymerase II promoter", "d": ["A process that stops, prevents or reduces the transition from the initiation to the elongation phases of transcription by RNA polymerase II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014807", "l": "regulation of somitogenesis", "d": ["Any process that modulates the frequency, rate or extent of somitogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.470950656012619", "identifiers": [{"i": "GO:0008406", "l": "gonad development", "d": ["The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032251", "l": "positive regulation of adenosine transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903904", "l": "negative regulation of establishment of T cell polarity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021506", "l": "anterior neuropore closure", "d": ["The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:2000416", "l": "regulation of eosinophil migration", "d": ["Any process that modulates the frequency, rate or extent of eosinophil migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021589", "l": "cerebellum structural organization", "d": ["The process that contributes to the act of creating the structural organization of the cerebellum. This process pertains to the physical shaping of a rudimentary structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903951", "l": "positive regulation of AV node cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of AV node cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035154", "l": "terminal cell fate specification, open tracheal system", "d": ["The process in which a cell in an open tracheal system becomes capable of differentiating autonomously into a terminal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Terminal cells send long and bifurcated hollow branches toward target tissues to allow oxygen exchange."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0099554", "l": "trans-synaptic signaling by soluble gas, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903988", "l": "iron ion export across plasma membrane", "d": ["The directed movement of iron ions from inside of a cell, across the plasma membrane and into the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070109", "l": "positive regulation of interleukin-27-mediated signaling pathway", "d": ["Any process that increases the rate, frequency or extent of an interleukin-27-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140493", "l": "very long-chain fatty acid beta-oxidation", "d": ["A fatty acid beta-oxidation pathway acting on a very long chain fatty acid, a fatty acid with an aliphatic tail of 22 or more carbons. The partway stars with the conversion of an acyl-CoA to a trans-2-enoyl-CoA, catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:1903305", "l": "regulation of regulated secretory pathway", "d": ["Any process that modulates the frequency, rate or extent of regulated secretory pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0035272", "l": "exocrine system development", "d": ["Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901232", "l": "regulation of convergent extension involved in axis elongation", "d": ["Any process that modulates the frequency, rate or extent of convergent extension involved in axis elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0055115", "l": "entry into diapause", "d": ["The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902638", "l": "neural crest cell differentiation involved in parathyroid gland development", "d": ["Any neural crest cell differentiation that is involved in parathyroid gland development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060692", "l": "mesenchymal cell differentiation involved in salivary gland development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.888270688603868", "identifiers": [{"i": "GO:0002526", "l": "acute inflammatory response", "d": ["Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900956", "l": "regulation of 17-methylnonadec-1-ene biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0019094", "l": "pole plasm mRNA localization", "d": ["Any process in which mRNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031215", "l": "shell calcification", "d": ["The precipitation of calcium carbonate onto the organic matrix of a shell, such as a mollusc shell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002452", "l": "B cell receptor editing", "d": ["The process of replacing receptors on B cells, in which RAG gene expression allows continued light-chain gene rearrangement and expression of a new light change which combines with the previous heavy chain to form a new receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0045807", "l": "positive regulation of endocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042423", "l": "catecholamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903460", "l": "mitotic DNA replication leading strand elongation", "d": ["Any leading strand elongation that is involved in mitotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0071456", "l": "cellular response to hypoxia", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901859", "l": "negative regulation of mitochondrial DNA metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002689", "l": "negative regulation of leukocyte chemotaxis", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.819490397197882", "identifiers": [{"i": "GO:0070201", "l": "regulation of establishment of protein localization", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072326", "l": "vulval cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell regardless of its environment; upon determination, the cell fate cannot be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902048", "l": "neosartoricin metabolic process", "d": ["The chemical reactions and pathways involving neosartoricin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009215", "l": "purine deoxyribonucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032736", "l": "positive regulation of interleukin-13 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-13 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000865", "l": "negative regulation of estradiol secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of estradiol secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014734", "l": "skeletal muscle hypertrophy", "d": ["The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060655", "l": "branching involved in mammary gland cord morphogenesis", "d": ["The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1900370", "l": "positive regulation of post-transcriptional gene silencing by RNA", "d": ["Any process that activates or increases the frequency, rate or extent of post-transcriptional gene silencing by RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090063", "l": "positive regulation of microtubule nucleation", "d": ["Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030710", "l": "regulation of border follicle cell delamination", "d": ["Any process that regulates the frequency, rate or extent of border cell delamination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002527", "l": "vasodilation involved in acute inflammatory response", "d": ["An increase in the internal diameter of blood vessels, especially arterioles or capillaries, usually resulting in a decrease in blood pressure contributing to an acute inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0009301", "l": "snRNA transcription", "d": ["The synthesis of small nuclear RNA (snRNA) from a DNA template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0003159", "l": "morphogenesis of an endothelium", "d": ["The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019351", "l": "dethiobiotin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dethiobiotin, a derivative of biotin in which the sulfur atom has been replaced by two hydrogen atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900140", "l": "regulation of seedling development", "d": ["Any process that modulates the frequency, rate or extent of seedling development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0045995", "l": "regulation of embryonic development", "d": ["Any process that modulates the frequency, rate or extent of embryonic development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072039", "l": "regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis", "d": ["Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032764", "l": "negative regulation of mast cell cytokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0032006", "l": "regulation of TOR signaling", "d": ["Any process that modulates the frequency, rate or extent of TOR signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901980", "l": "positive regulation of inward rectifier potassium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of inward rectifier potassium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:1902904", "l": "negative regulation of supramolecular fiber organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902926", "l": "inulin metabolic process", "d": ["The chemical reactions and pathways involving inulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902128", "l": "(-)-lariciresinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (-)-lariciresinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901817", "l": "beta-zeacarotene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of beta-zeacarotene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2001139", "l": "negative regulation of phospholipid transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110026", "l": "regulation of DNA strand resection involved in replication fork processing", "d": ["Any process that modulates the frequency, rate or extent of DNA strand resection involved in replication fork processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905828", "l": "regulation of prostaglandin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of prostaglandin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2001025", "l": "positive regulation of response to drug", "d": ["Any process that activates or increases the frequency, rate or extent of response to drug."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0002320", "l": "lymphoid progenitor cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072667", "l": "maintenance of protein location in vacuole", "d": ["Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098003", "l": "viral tail assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a virus tail."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901367", "l": "response to L-cysteine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042955", "l": "dextrin transport", "d": ["The directed movement of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140192", "l": "regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process", "d": ["Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:2000211", "l": "regulation of glutamate metabolic process", "d": ["Any process that modulates the frequency, rate or extent of glutamate metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990809", "l": "endoplasmic reticulum tubular network membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0072077", "l": "renal vesicle morphogenesis", "d": ["The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0031452", "l": "negative regulation of heterochromatin formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0031063", "l": "regulation of histone deacetylation", "d": ["Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070383", "l": "DNA cytosine deamination", "d": ["The removal of an amino group from a cytosine residue in DNA, forming a uracil residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0010640", "l": "regulation of platelet-derived growth factor receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030038", "l": "contractile actin filament bundle assembly", "d": ["Assembly of actin filament bundles in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032571", "l": "response to vitamin K", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000055", "l": "ribosomal large subunit export from nucleus", "d": ["The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903394", "l": "protein localization to kinetochore involved in kinetochore assembly", "d": ["Any protein localization to kinetochore that is involved in kinetochore assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034108", "l": "positive regulation of erythrocyte clearance", "d": ["Any process that activates or increases the frequency, rate, or extent of erythrocyte clearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070741", "l": "response to interleukin-6", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051467", "l": "detection of steroid hormone stimulus", "d": ["The series of events by which a steroid hormone stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098913", "l": "membrane depolarization during ventricular cardiac muscle cell action potential", "d": ["The process in which ventricular cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060359", "l": "response to ammonium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0001555", "l": "oocyte growth", "d": ["The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0086051", "l": "membrane repolarization during Purkinje myocyte action potential", "d": ["The process in which ions are transported across a membrane such that the Purkinje myocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045585", "l": "positive regulation of cytotoxic T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of cytotoxic T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904261", "l": "positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903062", "l": "regulation of reverse cholesterol transport", "d": ["Any process that modulates the frequency, rate or extent of reverse cholesterol transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.651716354923636", "identifiers": [{"i": "GO:0016049", "l": "cell growth", "d": ["The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900349", "l": "negative regulation of methane biosynthetic process from methylamine", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990167", "l": "protein K27-linked deubiquitination", "d": ["A protein deubiquitination process in which a K27-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is removed from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902083", "l": "negative regulation of peptidyl-cysteine S-nitrosylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-cysteine S-nitrosylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018152", "l": "peptide cross-linking via 3'-(1'-L-histidyl)-L-tyrosine", "d": ["The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3'-(1'-L-histidyl)-L-tyrosine protein cross-link."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000450", "l": "cleavage of bicistronic rRNA transcript (SSU-rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage of pre-rRNAs originally produced as a bicistronic rRNA transcript that contains the SSU-rRNA and the LSU-rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with two genes in this order are produced in Archaeal species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007495", "l": "visceral mesoderm-endoderm interaction involved in midgut development", "d": ["The process of cell-cell signaling between visceral mesoderm cells and endoderm cells that is involved in the differentiation of cells in the midgut."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043691", "l": "reverse cholesterol transport", "d": ["The directed movement of peripheral cell cholesterol, cholest-5-en-3-beta-ol, towards the liver for catabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060122", "l": "inner ear receptor cell stereocilium organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of inner ear receptor cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052028", "l": "induction by symbiont of host signal transduction pathway", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901060", "l": "p-hydroxyphenyl lignin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of p-hydroxyphenyl lignin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048542", "l": "lymph gland development", "d": ["The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is one of the sites of hemocyte differentiation. It consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905579", "l": "negative regulation of ERBB3 signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ERBB3 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901504", "l": "triazole transport", "d": ["The directed movement of a triazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905143", "l": "eukaryotic translation initiation factor 2 complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2 complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0099519", "l": "dense core granule cytoskeletal transport", "d": ["The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032250", "l": "negative regulation of adenosine transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033399", "l": "cis-zeatin metabolic process", "d": ["The chemical reactions and pathways involving cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:2000831", "l": "regulation of steroid hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of steroid hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990048", "l": "anterograde neuronal dense core vesicle transport", "d": ["The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045918", "l": "negative regulation of cytolysis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cytolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042867", "l": "pyruvate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyruvate, 2-oxopropanoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901599", "l": "(-)-pinoresinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (-)-pinoresinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000785", "l": "regulation of autophagosome assembly", "d": ["Any process that modulates the frequency, rate or extent of autophagosome assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0051236", "l": "establishment of RNA localization", "d": ["The directed movement of RNA to a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901885", "l": "2-hydroxybenzoyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving 2-hydroxybenzoyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071978", "l": "bacterial-type flagellum-dependent swarming motility", "d": ["Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0070602", "l": "regulation of centromeric sister chromatid cohesion", "d": ["Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061141", "l": "lung ciliated cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001403", "l": "invasive growth in response to glucose limitation", "d": ["A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904530", "l": "negative regulation of actin filament binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of actin filament binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015883", "l": "FAD transport", "d": ["The directed movement of flavin-adenine dinucleotide (FAD) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014825", "l": "stomach fundus smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the fundus of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fundus is the portion of the stomach that lies above the cardiac notch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150031", "l": "regulation of protein localization to lysosome", "d": ["Any process that modulates the frequency, rate or extent of protein localization to lysosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0055014", "l": "atrial cardiac muscle cell development", "d": ["The process whose specific outcome is the progression of an atrial cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903074", "l": "TRAIL death-inducing signaling complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a TRAIL death-inducing signaling complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001545", "l": "primary ovarian follicle growth", "d": ["Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072155", "l": "epithelial cell migration involved in nephron tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061560", "l": "cranial ganglion formation", "d": ["The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080126", "l": "ovary septum development", "d": ["The process whose specific outcome is the progression of the ovary septum over time, from its formation to the mature structure. The ovary septum is the thin partition that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022619", "l": "generative cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a generative cell. The generative cell gives rise to the sperm cells in the male gametophyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045663", "l": "positive regulation of myoblast differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001037", "l": "positive regulation of tongue muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902246", "l": "cis-abienol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cis-abienol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903629", "l": "positive regulation of dUTP diphosphatase activity", "d": ["Any process that activates or increases the frequency, rate or extent of dUTP diphosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000744", "l": "karyogamy involved in conjugation with mutual genetic exchange", "d": ["During sexual reproduction, the creation of a single nucleus from two nuclei as a result of fusing the nuclear envelopes that surround each nuclei. This takes place following the mutual exchange of one of the two nuclei produced by the mitosis that follows the second meiotic nuclear division. This occurs in ciliated protozoans such as Tetrahymena."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.069090159478471", "identifiers": [{"i": "GO:1903131", "l": "mononuclear cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060131", "l": "corticotropin hormone secreting cell development", "d": ["The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0031630", "l": "regulation of synaptic vesicle fusion to presynaptic active zone membrane", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120133", "l": "negative regulation of actin cortical patch assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin cortical patches."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044465", "l": "modulation of sensory perception of pain in another organism", "d": ["A process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal, in a different organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902751", "l": "positive regulation of cell cycle G2/M phase transition", "d": ["Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098714", "l": "malate import across plasma membrane", "d": ["The directed movement of malate from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060383", "l": "positive regulation of DNA strand elongation", "d": ["Any process that increases the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901124", "l": "bacitracin A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of bacitracin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0006754", "l": "ATP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042317", "l": "penicillin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019341", "l": "dibenzo-p-dioxin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901348", "l": "positive regulation of secondary cell wall biogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of secondary cell wall biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021757", "l": "caudate nucleus development", "d": ["The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0031505", "l": "fungal-type cell wall organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033537", "l": "ajugose biosynthetic process using galactinol:raffinose galactosyltransferase", "d": ["The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactinol:raffinose galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of galactinol to the oligosaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000822", "l": "regulation of behavioral fear response", "d": ["Any process that modulates the frequency, rate or extent of behavioral fear response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900070", "l": "negative regulation of cellular hyperosmotic salinity response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular hyperosmotic salinity response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0052559", "l": "induction by symbiont of host immune response", "d": ["Any process in which a symbiont activates the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0034091", "l": "regulation of maintenance of sister chromatid cohesion", "d": ["Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061056", "l": "sclerotome development", "d": ["The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905695", "l": "positive regulation of phosphatidic acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050972", "l": "detection of mechanical stimulus involved in echolocation", "d": ["The series of events involved in echolocation in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of a reflected sound wave (an echo), which the organism uses to determine the distance to the object that reflected the sound wave."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051257", "l": "meiotic spindle midzone assembly", "d": ["The formation of the spindle midzone, the area in the center of the spindle where the spindle microtubules from opposite poles overlap, as a part of the process of meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071038", "l": "nuclear polyadenylation-dependent tRNA catabolic process", "d": ["The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an aberrant or incorrectly modified transfer RNA (tRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.656143477476277", "identifiers": [{"i": "GO:0031347", "l": "regulation of defense response", "d": ["Any process that modulates the frequency, rate or extent of a defense response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018379", "l": "cytochrome c-heme linkage via heme-bis-L-cysteine", "d": ["The linkage of cytochromes and other heme proteins to heme via heme-bis-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045997", "l": "negative regulation of ecdysteroid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.149125385476992", "identifiers": [{"i": "GO:0045934", "l": "negative regulation of nucleobase-containing compound metabolic process", "d": ["Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099178", "l": "regulation of retrograde trans-synaptic signaling by endocanabinoid", "d": ["Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by an endocannabinoid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070509", "l": "calcium ion import", "d": ["The directed movement of calcium ions into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072318", "l": "clathrin coat disassembly", "d": ["The disaggregation of a clathrin coat into its constituent components; results in stripping or removing the clathrin coat from clathrin-coated vesicles (CCV) before fusing with their targets. CVVs transport cargo from plasma membrane and trans-Golgi to the endosomal system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904777", "l": "negative regulation of protein localization to cell cortex", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048673", "l": "collateral sprouting of intact axon in response to injury", "d": ["The process in which outgrowths develop from the axons of intact undamaged neurons as a result of injury to an axon. The collateral sprouts typically appear from undamaged axons in a tissue which has had part of its nerve supply removed, and they can often innervate successfully any cells that have lost some or all of their original synaptic input."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060915", "l": "mesenchymal cell differentiation involved in lung development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000911", "l": "positive regulation of sterol import", "d": ["Any process that activates or increases the frequency, rate or extent of sterol import."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071378", "l": "cellular response to growth hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905611", "l": "negative regulation of mRNA cap binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cap binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0002686", "l": "negative regulation of leukocyte migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901715", "l": "regulation of gamma-aminobutyric acid catabolic process", "d": ["Any process that modulates the frequency, rate or extent of gamma-aminobutyric acid catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901793", "l": "3-(3-hydroxyphenyl)propanoate metabolic process", "d": ["The chemical reactions and pathways involving 3-(3-hydroxyphenyl)propanoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030043", "l": "actin filament fragmentation", "d": ["The severing of actin filaments into numerous short fragments, usually mediated by actin severing proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903199", "l": "negative regulation of L-dopa decarboxylase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa decarboxylase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1990182", "l": "exosomal secretion", "d": ["The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000839", "l": "positive regulation of androstenedione secretion", "d": ["Any process that activates or increases the frequency, rate or extent of androstenedione secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014031", "l": "mesenchymal cell development", "d": ["The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0016131", "l": "brassinosteroid metabolic process", "d": ["The chemical reactions and pathways involving brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905890", "l": "regulation of cellular response to very-low-density lipoprotein particle stimulus", "d": ["Any process that modulates the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0101026", "l": "mitotic nuclear membrane biogenesis", "d": ["A process in which the nuclear inner or outer membrane is synthesized, aggregates, and bonds together during mitotic nuclear division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051792", "l": "medium-chain fatty acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a fatty acid with an aliphatic tail of 6 to 12 carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071400", "l": "cellular response to oleic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0018945", "l": "organosilicon metabolic process", "d": ["The chemical reactions and pathways involving any organosilicon, organic compounds that contain silicon, a nonmetal element analogous to carbon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900873", "l": "pentadec-1-ene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pentadec-1-ene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033360", "l": "lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate", "d": ["The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and L-2-acetamido-6-oxoheptanedioate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006556", "l": "S-adenosylmethionine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033088", "l": "negative regulation of immature T cell proliferation in thymus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903424", "l": "fluoride transmembrane transport", "d": ["The process in which fluoride is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0043277", "l": "apoptotic cell clearance", "d": ["The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903295", "l": "negative regulation of glutamate secretion, neurotransmission", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glutamate secretion, neurotransmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002529", "l": "regulation of plasma kallikrein-kinin cascade", "d": ["Any process that modulates the frequency, rate, or extent of the plasma kallikrein-kinin cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042884", "l": "microcin transport", "d": ["The directed movement of microcin, a class of glycine-rich, bactericidal peptides (antibiotics) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903372", "l": "negative regulation of endoplasmic reticulum tubular network organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum tubular network organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0043474", "l": "pigment metabolic process involved in pigmentation", "d": ["The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007221", "l": "positive regulation of transcription of Notch receptor target", "d": ["The activation of transcription of specific genes as a result of Notch signaling, mediated by the Notch intracellular domain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090315", "l": "negative regulation of protein targeting to membrane", "d": ["Any process that decreases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000427", "l": "positive regulation of apoptotic cell clearance", "d": ["Any process that activates or increases the frequency, rate or extent of apoptotic cell clearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901113", "l": "erythromycin metabolic process", "d": ["The chemical reactions and pathways involving erythromycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902949", "l": "positive regulation of tau-protein kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of tau-protein kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015745", "l": "tartrate transmembrane transport", "d": ["The process in which tartrate is transported across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030909", "l": "non-intein-mediated protein splicing", "d": ["The post-translational removal of peptide sequences from within a protein sequence, by a process not involving inteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071298", "l": "cellular response to L-ascorbic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032323", "l": "lipoate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lipoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010895", "l": "negative regulation of ergosterol biosynthetic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060980", "l": "cell migration involved in coronary vasculogenesis", "d": ["The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000094", "l": "negative regulation of mesonephric nephron tubule epithelial cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060409", "l": "positive regulation of acetylcholine metabolic process", "d": ["Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903519", "l": "regulation of mammary gland involution", "d": ["Any process that modulates the frequency, rate or extent of mammary gland involution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000493", "l": "box H/ACA snoRNP assembly", "d": ["The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0072171", "l": "mesonephric tubule morphogenesis", "d": ["The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0021783", "l": "preganglionic parasympathetic fiber development", "d": ["The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051496", "l": "positive regulation of stress fiber assembly", "d": ["Any process that activates or increases the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003227", "l": "right ventricular trabecular myocardium morphogenesis", "d": ["The process in which the anatomical structures of the right ventricular myocardium are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903915", "l": "positive regulation of fusion of virus membrane with host plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of fusion of virus membrane with host plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033055", "l": "D-arginine metabolic process", "d": ["The chemical reactions and pathways involving D-arginine, the D-enantiomer of the amino acid arginine, i.e. (2R)-2-amino-5-(carbamimidamido)pentanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070490", "l": "protein pupylation", "d": ["The process in which a Pup protein is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of Pup and the epsilon-amino group of a lysine residue of the target protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902312", "l": "negative regulation of copper ion transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of copper ion transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010989", "l": "negative regulation of low-density lipoprotein particle clearance", "d": ["Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046671", "l": "negative regulation of retinal cell programmed cell death", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042413", "l": "carnitine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901521", "l": "aspyridone B biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aspyridone B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.509418971541265", "identifiers": [{"i": "GO:0015872", "l": "dopamine transport", "d": ["The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014001", "l": "sclerenchyma cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a sclerenchyma cell. A sclerenchyma cell is a plant cell with thick lignified walls, normally dead at maturity and specialized for structural strength. Includes fiber cells, that are greatly elongated; and sclereids, that are more isodiametric. Intermediate types exist. Cells may or may not be devoid of protoplasm at maturity. Cell form and size are variable."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1904338", "l": "regulation of dopaminergic neuron differentiation", "d": ["Any process that modulates the frequency, rate or extent of dopaminergic neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0001806", "l": "type IV hypersensitivity", "d": ["An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009199", "l": "ribonucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000032", "l": "cell wall mannoprotein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001099", "l": "maltotetraose transport", "d": ["The directed movement of a maltotetraoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0099174", "l": "regulation of presynapse organization", "d": ["Any process that modulates the physical form of a presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018243", "l": "protein O-linked glycosylation via threonine", "d": ["The glycosylation of protein via the O3 atom of peptidyl-threonine, forming O3-glycosyl-L-threonine; the most common forms are N-acetylgalactosaminyl, mannosyl, and galactosyl threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042685", "l": "cardioblast cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a cardioblast cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003239", "l": "conus arteriosus morphogenesis", "d": ["The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033319", "l": "UDP-D-xylose metabolic process", "d": ["The chemical reactions and pathways involving UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070460", "l": "thyroid-stimulating hormone secretion", "d": ["The regulated release of thyroid-stimulating hormone, a peptide hormone that stimulates the activity of the thyroid gland, from secretory granules in the anterior pituitary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035156", "l": "fusion cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a fusion cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Fusion cells allow the interconnection of adjacent tracheal metameres during tracheal tube fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904274", "l": "tricellular tight junction assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a tricellular tight junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0086019", "l": "cell-cell signaling involved in cardiac conduction", "d": ["Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905824", "l": "positive regulation of mitotic sister chromatid arm separation", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid arm separation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036107", "l": "4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate metabolic process", "d": ["The chemical reactions and pathways involving 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904055", "l": "negative regulation of cholangiocyte proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160078", "l": "negative regulation of lipid droplet fusion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lipid droplet fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021665", "l": "rhombomere 5 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 5. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:1902404", "l": "mitotic actomyosin contractile ring contraction", "d": ["Any actomyosin contractile ring contraction that is involved in mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900847", "l": "negative regulation of naphtho-gamma-pyrone biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901052", "l": "sarcosine metabolic process", "d": ["The chemical reactions and pathways involving sarcosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070777", "l": "D-aspartate transport", "d": ["The directed movement of D-aspartate, the D-enantiomer of the anion of (2R)-2-aminobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904656", "l": "regulation of sensory perception of sweet taste", "d": ["Any process that modulates the frequency, rate or extent of sensory perception of sweet taste."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044622", "l": "negative regulation of cell migration in another organism", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045831", "l": "negative regulation of light-activated channel activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of light-activated channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901176", "l": "lycopene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lycopene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.071082486141265", "identifiers": [{"i": "GO:0030488", "l": "tRNA methylation", "d": ["The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006864", "l": "pyrimidine nucleotide transport", "d": ["The directed movement of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, into, out of or within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072383", "l": "plus-end-directed vesicle transport along microtubule", "d": ["The directed movement of a vesicle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140464", "l": "subnuclear spatial organization of silent mating-type cassette heterochromatin", "d": ["The localization of silent mating-type cassette heterochromatin at a specific location in the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900453", "l": "negative regulation of long-term synaptic depression", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of long term synaptic depression."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902635", "l": "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006222", "l": "UMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097402", "l": "neuroblast migration", "d": ["The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903709", "l": "uterine gland development", "d": ["The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036521", "l": "modulation by symbiont of host protein localization to phagocytic vesicle", "d": ["Any process in which an organism modulates the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071703", "l": "detection of organic substance", "d": ["The series of events in which an organic substance stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001116", "l": "protein-DNA-RNA complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins, DNA, and RNA molecules to form a protein-DNA-RNA complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072223", "l": "metanephric glomerular mesangium development", "d": ["The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036116", "l": "long-chain fatty-acyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072725", "l": "cellular response to 4-nitroquinoline N-oxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905839", "l": "negative regulation of telomeric D-loop disassembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomeric D-loop disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0044580", "l": "butyryl-CoA catabolic process", "d": ["The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061000", "l": "negative regulation of dendritic spine development", "d": ["Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033274", "l": "response to vitamin B2", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:1901880", "l": "negative regulation of protein depolymerization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905904", "l": "positive regulation of mesoderm formation", "d": ["Any process that activates or increases the frequency, rate or extent of mesoderm formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072090", "l": "mesenchymal stem cell proliferation involved in nephron morphogenesis", "d": ["The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population, that contributes to the shaping of a nephron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0006571", "l": "tyrosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048834", "l": "specification of petal number", "d": ["Any process that modulates the number of petals formed in a flower."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060115", "l": "vestibular receptor cell fate commitment", "d": ["The process in which a cell becomes committed to become a vestibular receptor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000481", "l": "maturation of 5S rRNA", "d": ["Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901373", "l": "lipid hydroperoxide transport", "d": ["The directed movement of a lipid hydroperoxide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903280", "l": "negative regulation of calcium:sodium antiporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium:sodium antiporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043353", "l": "enucleate erythrocyte differentiation", "d": ["The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900670", "l": "regulation of F-9775A biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of F-9775A biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009769", "l": "photosynthesis, light harvesting in photosystem II", "d": ["After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem II, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090053", "l": "positive regulation of pericentric heterochromatin formation", "d": ["Any process that increases the frequency, rate or extent of pericentric heterochromatin formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072260", "l": "metanephric interstitial fibroblast fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric interstitial fibroblast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019560", "l": "histidine catabolic process to hydantoin-5-propionate", "d": ["The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including hydantoin-5-propionate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032627", "l": "interleukin-23 production", "d": ["The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046529", "l": "imaginal disc fusion, thorax closure", "d": ["The joining of the parts of the wing imaginal discs, giving rise to the adult thorax."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072029", "l": "long nephron development", "d": ["The process whose specific outcome is the progression of a long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0002691", "l": "regulation of cellular extravasation", "d": ["Any process that modulates the frequency, rate, or extent of cellular extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061573", "l": "actin filament bundle retrograde transport", "d": ["A process of actin filament bundle distribution that results in the arrangement of actin filament bundles from the periphery toward the interior of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062027", "l": "positive regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process", "d": ["Any process that starts or increases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061511", "l": "centriole elongation", "d": ["The centrosome organization process by which a centriole increases in length as part of the process of replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0001787", "l": "natural killer cell proliferation", "d": ["The expansion of a natural killer cell population by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097053", "l": "L-kynurenine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0018256", "l": "protein formylation", "d": ["The addition of a formyl group to a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048197", "l": "Golgi membrane coat protein complex assembly", "d": ["The aggregation, arrangement and bonding together of priming complexes to form a coat on a Golgi membrane. Priming complexes associate laterally and additional coat proteins are recruited from the cytosol to the forming coat. Cargo proteins diffuse into the budding site and become trapped by their interactions with the coat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110066", "l": "negative regulation of interphase mitotic telomere clustering", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mitotic telomere clustering during interphase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900515", "l": "regulation of xylose catabolic process to ethanol", "d": ["Any process that modulates the frequency, rate or extent of xylose catabolic process to ethanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0010633", "l": "negative regulation of epithelial cell migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010755", "l": "regulation of plasminogen activation", "d": ["Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900095", "l": "regulation of dosage compensation by inactivation of X chromosome", "d": ["Any process that modulates the frequency, rate or extent of dosage compensation, by inactivation of X chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0001910", "l": "regulation of leukocyte mediated cytotoxicity", "d": ["Any process that modulates the frequency, rate, or extent of leukocyte mediated cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0072002", "l": "Malpighian tubule development", "d": ["The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019074", "l": "viral RNA genome packaging", "d": ["The packaging of viral RNA (single-stranded or double-stranded) into a nucleocapsid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030717", "l": "oocyte karyosome formation", "d": ["The chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061168", "l": "regulation of hair follicle placode formation", "d": ["Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0035337", "l": "fatty-acyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903297", "l": "regulation of hypoxia-induced intrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903272", "l": "positive regulation of cytoplasmic translational elongation through polyproline stretches", "d": ["Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070407", "l": "oxidation-dependent protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the oxidation of one or more amino acid residues in the protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031460", "l": "glycine betaine transport", "d": ["The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0033081", "l": "regulation of T cell differentiation in thymus", "d": ["Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071213", "l": "cellular response to 1-aminocyclopropane-1-carboxylic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0043392", "l": "negative regulation of DNA binding", "d": ["Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000430", "l": "regulation of transcription from RNA polymerase II promoter by glucose", "d": ["Any process involving glucose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061355", "l": "Wnt protein secretion", "d": ["The controlled release of a Wnt protein from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901776", "l": "mitomycin C catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mitomycin C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900093", "l": "positive regulation of raffinose biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of raffinose biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0090718", "l": "adaptive immune effector response", "d": ["An adaptive immune response that involves one or more immune effector processes and takes place during the effector phase of the adaptive immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900578", "l": "gerfelin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of gerfelin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900602", "l": "endocrocin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of endocrocin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902982", "l": "DNA strand elongation involved in premeiotic DNA replication", "d": ["Any DNA strand elongation involved in meiotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070430", "l": "positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904598", "l": "positive regulation of connective tissue replacement involved in inflammatory response wound healing", "d": ["Any process that activates or increases the frequency, rate or extent of wound healing connective tissue replacement, which may be replaced with fibrotic material, that occurs as part of an inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905679", "l": "positive regulation of adaptive immune effector response", "d": ["Any process that activates or increases the frequency, rate or extent of adaptive immune effector response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080040", "l": "positive regulation of cellular response to phosphate starvation", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to phosphate starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099703", "l": "induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration", "d": ["The induction of synaptic vesicle release by any process that leads to a rise in intracellular calcium ion concentration at the presynapse. This is the first step in synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002812", "l": "biosynthetic process of antibacterial peptides active against Gram-negative bacteria", "d": ["The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-negative bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.481503109560144", "identifiers": [{"i": "GO:0044403", "l": "biological process involved in symbiotic interaction", "d": ["A process carried out by gene products in an organism that enable the organism to engage in a symbiotic relationship, a more or less intimate association, with another organism. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061031", "l": "endodermal digestive tract morphogenesis", "d": ["The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090028", "l": "positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion", "d": ["Any process that increases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0009133", "l": "nucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903971", "l": "positive regulation of response to macrophage colony-stimulating factor", "d": ["Any process that activates or increases the frequency, rate or extent of response to macrophage colony-stimulating factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051464", "l": "positive regulation of cortisol secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of cortisol from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042666", "l": "negative regulation of ectodermal cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from specifying into an ectoderm cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014045", "l": "establishment of endothelial blood-brain barrier", "d": ["Establishment of the endothelial barrier between the blood and the brain. The endothelial cells in the brain capillaries are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060523", "l": "prostate epithelial cord elongation", "d": ["The developmental growth process in which solid chords of prostate epithelium increase in length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901393", "l": "negative regulation of transforming growth factor beta1 activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta1 activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0097300", "l": "programmed necrotic cell death", "d": ["A necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900270", "l": "positive regulation of reverse transcription", "d": ["Any process that activates or increases the frequency, rate or extent of reverse transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.000891501185137", "identifiers": [{"i": "GO:0033260", "l": "nuclear DNA replication", "d": ["The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060272", "l": "embryonic skeletal joint morphogenesis", "d": ["The process in which the anatomical structures of skeletal joints are generated and organized during the embryonic phase. A skeletal joint is the connecting structure between the bones of the skeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990431", "l": "priRNA 3'-end processing", "d": ["The process of forming the mature 3' end of a priRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900187", "l": "regulation of cell adhesion involved in single-species biofilm formation", "d": ["Any process that modulates the frequency, rate or extent of cell adhesion involved in single-species biofilm formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0001911", "l": "negative regulation of leukocyte mediated cytotoxicity", "d": ["Any process that stops, prevents, or reduces the rate of leukocyte mediated cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0051305", "l": "chromosome movement towards spindle pole", "d": ["The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043567", "l": "regulation of insulin-like growth factor receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of insulin-like growth factor receptor signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904043", "l": "positive regulation of cystathionine beta-synthase activity", "d": ["Any process that activates or increases the frequency, rate or extent of cystathionine beta-synthase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070433", "l": "negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036051", "l": "protein localization to trailing edge", "d": ["A process in which a protein is transported to, or maintained at, the trailing edge. The trailing edge is the area of a motile cell opposite to the direction of movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097222", "l": "mitochondrial mRNA polyadenylation", "d": ["The enzymatic addition of a sequence of 40-60 adenylyl residues at the 3' end of a eukaryotic mitochondrial mRNA primary transcript. Mitochondria contain both stabilizing and destabilizing poly(A) tails."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034429", "l": "tectobulbar tract morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:2000116", "l": "regulation of cysteine-type endopeptidase activity", "d": ["Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905582", "l": "response to mannose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043571", "l": "maintenance of CRISPR repeat elements", "d": ["Any process involved in sustaining CRISPR repeat clusters, including capture of new spacer elements, expansion or contraction of clusters, propagation of the leader sequence and repeat clusters within a genome, transfer of repeat clusters and CRISPR-associated (cas) genes to new genomes, transcription of the CRISPR repeat arrays into RNA and processing, and interaction of CRISPR/cas loci with the host genome. CRISPR (clustered regularly interspaced short palindromic repeat) elements are a family of sequence elements containing multiple direct repeats of 24-48 bp with weak dyad symmetry which are separated by regularly sized nonrepetitive spacer sequences."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097551", "l": "mitochondrial double-strand break repair", "d": ["The repair of double-strand breaks in mitochondrial DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0032351", "l": "negative regulation of hormone metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002099", "l": "tRNA wobble guanine modification", "d": ["The process in which a guanine in t position 34 of a tRNA is post-transcriptionally modified."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900572", "l": "diorcinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of diorcinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048823", "l": "nucleate erythrocyte development", "d": ["The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001507", "l": "acetylcholine catabolic process in synaptic cleft", "d": ["The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003185", "l": "sinoatrial valve morphogenesis", "d": ["The process in which the structure of the sinoatrial valve is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030812", "l": "negative regulation of nucleotide catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046279", "l": "3,4-dihydroxybenzoate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 3,4-dihydroxybenzoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901328", "l": "response to cytochalasin B", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032186", "l": "cellular bud neck septin ring organization", "d": ["Control of the formation, spatial distribution, and breakdown of a septin ring located at the bud neck."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009684", "l": "indoleacetic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of indole-3-acetic acid, a compound which functions as a growth regulator in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:1900908", "l": "regulation of olefin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of olefin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018238", "l": "peptidyl-lysine carboxyethylation", "d": ["The modification of peptidyl-lysine to form peptidyl-N6-1-carboxyethyl-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000840", "l": "regulation of dehydroepiandrosterone secretion", "d": ["Any process that modulates the frequency, rate or extent of dehydroepiandrosterone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039685", "l": "rolling hairpin viral DNA replication", "d": ["A viral DNA replication process where a 3' hairpin structure in the viral single-stranded DNA (ssDNA) template serves as a primer for host enzymes to synthesize DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904686", "l": "regulation of mitotic spindle disassembly", "d": ["Any process that modulates the frequency, rate or extent of mitotic spindle disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034233", "l": "regulation of cell wall chitin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cell wall chitin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904419", "l": "negative regulation of telomeric loop formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061614", "l": "miRNA transcription", "d": ["The cellular synthesis of microRNA (miRNA) transcripts. MicroRNA genes are synthesized as primary (pri) miRNA transcripts and subsequently processed to produce the ~22nt miRNAs that function in gene regulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097390", "l": "chemokine (C-X-C motif) ligand 12 production", "d": ["The appearance of chemokine (C-X-C motif) ligand 12 (CXCL12) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010081", "l": "regulation of inflorescence meristem growth", "d": ["Any process involved in maintaining the size and shape of an inflorescence meristem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:1901381", "l": "positive regulation of potassium ion transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048264", "l": "determination of ventral identity", "d": ["The regionalization process that results in the determination of the identity of part of an organism or organ where those parts are of the type that occur in the ventral region. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036350", "l": "mannose-specific flocculation", "d": ["The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to mannose residues on the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0006998", "l": "nuclear envelope organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048919", "l": "posterior lateral line neuromast development", "d": ["The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060806", "l": "negative regulation of cell differentiation involved in embryonic placenta development", "d": ["Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900268", "l": "regulation of reverse transcription", "d": ["Any process that modulates the frequency, rate or extent of reverse transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000341", "l": "regulation of chemokine (C-X-C motif) ligand 2 production", "d": ["Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051550", "l": "aurone metabolic process", "d": ["The chemical reactions and pathways involving aurones, a series of plant flavonoids that provide a yellow colour to flowers. They have the basic skeletal structure of two benzene rings joined by a linear C3 chain (C6-C3-C6). Aurones exist mostly as 6-O-glucosides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021764", "l": "amygdala development", "d": ["The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150143", "l": "regulation of CD80 production", "d": ["Any process that modulates the frequency, rate or extent of CD80 biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043551", "l": "regulation of phosphatidylinositol 3-kinase activity", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylinositol 3-kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an inositol lipid at the 3' position of the inositol ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.655739316124155", "identifiers": [{"i": "GO:0009308", "l": "amine metabolic process", "d": ["The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002800", "l": "regulation of antifungal peptide secretion", "d": ["Any process that modulates the frequency, rate, or extent of antifungal peptide secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901547", "l": "negative regulation of synaptic vesicle lumen acidification", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle lumen acidification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032024", "l": "positive regulation of insulin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of insulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0050846", "l": "teichuronic acid metabolic process", "d": ["The chemical reactions and pathways involving teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0032891", "l": "negative regulation of organic acid transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051936", "l": "gamma-aminobutyric acid reuptake", "d": ["The uptake of gamma-aminobutyric acid (GABA, 4-aminobutyrate) by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072249", "l": "metanephric podocyte development", "d": ["The process whose specific outcome is the progression of a metanephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051140", "l": "regulation of NK T cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of natural killer T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010731", "l": "protein glutathionylation", "d": ["The protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032085", "l": "regulation of type II site-specific deoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of a type II restriction endodeoxyribonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106121", "l": "positive regulation of cobalamin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of a cobalamin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901118", "l": "cephamycin C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cephamycin C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019426", "l": "bisulfite reduction", "d": ["The chemical reactions and pathways resulting in the reduction of sulfate to thiosulfate via bisulfite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010483", "l": "pollen tube reception", "d": ["Interaction between the pollen tube, part of the male gametophyte, and the ovule, part of the female gametophyte, that results in the arrest of pollen tube growth, rupture of the pollen tube and the release of the sperm cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042248", "l": "maintenance of polarity of follicular epithelium", "d": ["The maintenance of an established polarized follicular epithelial sheet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904247", "l": "positive regulation of polynucleotide adenylyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of polynucleotide adenylyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051896", "l": "regulation of protein kinase B signaling", "d": ["Any process that modulates the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903862", "l": "positive regulation of oxidative phosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902120", "l": "negative regulation of meiotic spindle elongation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of meiotic spindle elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048611", "l": "embryonic ectodermal digestive tract development", "d": ["The process, occurring during the embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0009953", "l": "dorsal/ventral pattern formation", "d": ["The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006307", "l": "DNA dealkylation involved in DNA repair", "d": ["The repair of alkylation damage, e.g. the removal of the alkyl group at the O6-position of guanine by O6-alkylguanine-DNA alkyltransferase (AGT)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010568", "l": "regulation of budding cell apical bud growth", "d": ["Any process that modulates the frequency, rate or extent of growth at the tip of a bud, in a cell that reproduces by budding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035513", "l": "oxidative RNA demethylation", "d": ["The removal of the methyl group from one or more nucleotides within an RNA molecule involving oxidation (i.e. electron loss) of one or more atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045540", "l": "regulation of cholesterol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039579", "l": "suppression by virus of host ISG15-protein conjugation", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host ubiquitin-like protein ISG15 conjugation to a susbtrate. ISG15 is a ubiquitin-like protein that is conjugated to lysine residues on various target proteins. Viruses escape from the antiviral activity of ISG15 by using different mechanisms; the influenza B virus NS1 protein for instance blocks the covalent linkage of ISG15 to its target proteins by directly interacting with ISG15. The papain-like protease from the coronavirus cleaves ISG15 derivatives."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021855", "l": "hypothalamus cell migration", "d": ["The directed movement of a cell into the hypothalamus region of the forebrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.773387538292397", "identifiers": [{"i": "GO:0044036", "l": "cell wall macromolecule metabolic process", "d": ["The chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1902025", "l": "nitrate import", "d": ["The directed movement of nitrate into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905410", "l": "regulation of mitotic cohesin unloading", "d": ["Any process that modulates the frequency, rate or extent of mitotic cohesin unloading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034342", "l": "response to type III interferon", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006669", "l": "sphinganine-1-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045902", "l": "negative regulation of translational fidelity", "d": ["Any process that decreases the ability of the translational apparatus to interpret the genetic code."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006032", "l": "chitin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001079", "l": "nitrogen catabolite regulation of transcription from RNA polymerase II promoter", "d": ["A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904853", "l": "protein localization to ascospore wall", "d": ["A process in which a protein is transported to, or maintained in, a location within an ascospore wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034653", "l": "retinoic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021622", "l": "oculomotor nerve morphogenesis", "d": ["The process in which the anatomical structure of the oculomotor nerve is generated and organized. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900436", "l": "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation", "d": ["Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007534", "l": "gene conversion at mating-type locus", "d": ["The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030208", "l": "dermatan sulfate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dermatan sulfate, any glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036084", "l": "GDP-fucose import into endoplasmic reticulum lumen", "d": ["The directed movement of GDP-fucose into the endoplasmic reticulum lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030949", "l": "positive regulation of vascular endothelial growth factor receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900178", "l": "negative regulation of aflatoxin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aflatoxin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043707", "l": "cell adhesion involved in single-species biofilm formation in or on host organism", "d": ["The attachment of a cell to either a host cell or a microbial cell of the same species, or to an underlying host substrate, such as the extracellular matrix, via cell adhesion molecules, occurring during the formation of a biofilm in or on a host species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003019", "l": "central nervous system control of baroreceptor feedback", "d": ["The neurological process in which nerve impulses arising in the aorta or the carotid sinuses travel to the medulla and reach the nucleus of tractus solaris."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106410", "l": "box C/D RNA 5'-end processing", "d": ["Any process involved in forming the mature 5' end of a box C/D RNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902355", "l": "endothelial tube lumen extension involved in blood vessel lumen ensheathment", "d": ["Any endothelial tube lumen extension that is involved in blood vessel lumen ensheathment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097118", "l": "neuroligin clustering involved in postsynaptic membrane assembly", "d": ["The receptor clustering process involved in assembly of the postsynaptic membrane in which neuroligins are localized to distinct domains in the cell membrane. Neuroligins are neuronal cell surface proteins on the postsynaptic membrane that mediate synapse formation between neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021859", "l": "pyramidal neuron differentiation", "d": ["The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901178", "l": "spheroidene metabolic process", "d": ["The chemical reactions and pathways involving spheroidene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021839", "l": "interneuron-substratum interaction involved in interneuron migration from the subpallium to the cortex", "d": ["The process in which migrating interneurons interact with an external substratum as a component of migration from the subpallium to the cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001095", "l": "mannotriose transport", "d": ["The directed movement of a mannotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048734", "l": "proboscis morphogenesis", "d": ["The process in which the anatomical structures of the proboscis are generated and organized. The proboscis is the trunk-like extension of the mouthparts on the adult head."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903889", "l": "negative regulation of plant epidermal cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plant epidermal cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072116", "l": "pronephros formation", "d": ["The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0120168", "l": "detection of hot stimulus involved in thermoception", "d": ["The series of events in which a hot stimulus is received and converted into a molecular signal as part of thermoception."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090265", "l": "positive regulation of immune complex clearance by monocytes and macrophages", "d": ["Any process that increases the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000954", "l": "methionine catabolic process to 3-methylthiopropanoate", "d": ["The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanoate is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002563", "l": "somatic diversification of immune receptors via alternate splicing", "d": ["The process in which immune receptor genes are diversified through alternate splicing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110069", "l": "syncytial embryo cellularization", "d": ["The separation of a syncytial embryo into individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048394", "l": "intermediate mesodermal cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a intermediate mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000261", "l": "negative regulation of blood coagulation, common pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, common pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000163", "l": "regulation of planar cell polarity pathway involved in outflow tract morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050493", "l": "GPI anchor biosynthetic process via N-threonyl-glycosylphosphatidylinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-threonyl ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a threonyl-peptide bond in the carboxy-terminal region of a membrane-associated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904320", "l": "positive regulation of smooth muscle contraction involved in micturition", "d": ["Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072151", "l": "mesangial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesangial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0000019", "l": "regulation of mitotic recombination", "d": ["Any process that modulates the frequency, rate or extent of DNA recombination during mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048095", "l": "female pigmentation", "d": ["Establishment of a pattern of pigment in females."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003075", "l": "renal vasodilation of the peripheral vascular system involved in regulation of systemic arterial blood pressure", "d": ["The renal process that modulates the force with which blood travels through the circulatory system, by vasodilation of the peripheral vascular system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015769", "l": "melibiose transport", "d": ["The directed movement of melibiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000457", "l": "endonucleolytic cleavage between SSU-rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)", "d": ["Endonucleolytic cleavage to separate a pre-SSU-rRNA from a pre-LSU-rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.98780181426379", "identifiers": [{"i": "GO:1903531", "l": "negative regulation of secretion by cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "48.861480641430951", "identifiers": [{"i": "GO:0031323", "l": "regulation of cellular metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003120", "l": "regulation of vasoconstriction by circulating epinephrine", "d": ["Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000834", "l": "regulation of androgen secretion", "d": ["Any process that modulates the frequency, rate or extent of androgen secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900816", "l": "ochratoxin A metabolic process", "d": ["The chemical reactions and pathways involving ochratoxin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1905033", "l": "positive regulation of membrane repolarization during cardiac muscle cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0007484", "l": "imaginal disc-derived genitalia development", "d": ["The process whose specific outcome is the progression of the genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905034", "l": "regulation of antifungal innate immune response", "d": ["Any process that modulates the frequency, rate or extent of an antifungal innate immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.585103934178449", "identifiers": [{"i": "GO:0120255", "l": "olefinic compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0052863", "l": "1-deoxy-D-xylulose 5-phosphate metabolic process", "d": ["The chemical reactions and pathways involving 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034169", "l": "positive regulation of toll-like receptor 10 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 10 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.576417257927446", "identifiers": [{"i": "GO:0009101", "l": "glycoprotein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902843", "l": "positive regulation of netrin-activated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of netrin-activated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.843307841253292", "identifiers": [{"i": "GO:0051253", "l": "negative regulation of RNA metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035609", "l": "C-terminal protein deglutamylation", "d": ["The removal of a C-terminal, gene-encoded glutamate residue from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901386", "l": "negative regulation of voltage-gated calcium channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:1901978", "l": "positive regulation of cell cycle checkpoint", "d": ["Any process that activates or increases the frequency, rate or extent of cell cycle checkpoint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0098721", "l": "uracil import across plasma membrane", "d": ["The directed movement of uracil from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061719", "l": "glucose catabolic process to pyruvate utilizing ADP", "d": ["The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, with the concomitant production of a small amount of ATP and the utilization of ADP in the initial kinase reactions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072672", "l": "neutrophil extravasation", "d": ["The migration of a neutrophil from the blood vessels into the surrounding tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902668", "l": "negative regulation of axon guidance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0120077", "l": "angiogenic sprout fusion", "d": ["The connection of an angiogenic sprout to another vessel or sprout during the formation of vascular networks by sprouting angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.79713023523334", "identifiers": [{"i": "GO:0033674", "l": "positive regulation of kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0033517", "l": "myo-inositol hexakisphosphate metabolic process", "d": ["The chemical reactions and pathways involving phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.576417257927446", "identifiers": [{"i": "GO:0048762", "l": "mesenchymal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010403", "l": "pectic arabinogalactan I metabolic process", "d": ["The chemical reactions and pathways involving pectic arabinogalactan I, an alpha-(1,4)-linked D-galactopyranose backbone that is substituted with alpha-l-Araf residues via the O-3 of the D-galactose residues. Arabinogalactan I can be found as a side chain of rhamnogalacturonan I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900277", "l": "negative regulation of proteinase activated receptor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of proteinase activated receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0016110", "l": "tetraterpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tetraterpenoid compounds, terpenoids with eight isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000712", "l": "resolution of meiotic recombination intermediates", "d": ["The cleavage and rejoining of intermediates, such as Holliday junctions, formed during meiotic recombination to produce two intact molecules in which genetic material has been exchanged."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0061240", "l": "mesonephric nephron tubule morphogenesis", "d": ["The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140961", "l": "cellular detoxification of metal ion", "d": ["Any process carried out at the cellular level that reduces or removes the toxicity of a metal ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021617", "l": "glossopharyngeal nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the glossopharyngeal nerve. This process pertains to the physical shaping of a rudimentary structure. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031118", "l": "rRNA pseudouridine synthesis", "d": ["The intramolecular conversion of uridine to pseudouridine in an rRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039540", "l": "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity", "d": ["Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of RIG-1 (also known as DDX58). The cytoplasmic pattern recognition RIG-I recognizes viral RNA synthesized during active viral replication and signals to protect the host against viral infection, for example by inducing the expression of antiviral cytokines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0009272", "l": "fungal-type cell wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a fungal-type cell wall. The fungal-type cell wall contains beta-glucan and may contain chitin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0030878", "l": "thyroid gland development", "d": ["The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904660", "l": "regulation of sensory perception of bitter taste", "d": ["Any process that modulates the frequency, rate or extent of sensory perception of bitter taste."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006218", "l": "uridine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033489", "l": "cholesterol biosynthetic process via desmosterol", "d": ["The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate desmosterol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901221", "l": "positive regulation of cardiac chamber morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018363", "l": "peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium", "d": ["The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072461", "l": "response to meiotic recombination checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of meiotic recombination checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000342", "l": "negative regulation of chemokine (C-X-C motif) ligand 2 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032438", "l": "melanosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045221", "l": "negative regulation of FasL production", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032702", "l": "negative regulation of interleukin-19 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-19 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018870", "l": "anaerobic 2-aminobenzoate metabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-aminobenzoate, a derivative of benzoic acid with an NH2 group attached to C2, that occurs in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099539", "l": "neuropeptide secretion from presynapse", "d": ["The secretion of neuropeptides contained within a dense core vesicle by fusion of the granule with the presynaptic membrane, stimulated by a rise in cytosolic calcium ion concentration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905849", "l": "negative regulation of forward locomotion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of forward locomotion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048728", "l": "proboscis development", "d": ["The process whose specific outcome is the progression of the proboscis over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901828", "l": "zeaxanthin bis(beta-D-glucoside) metabolic process", "d": ["The chemical reactions and pathways involving zeaxanthin bis(beta-D-glucoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905899", "l": "regulation of smooth muscle tissue development", "d": ["Any process that modulates the frequency, rate or extent of smooth muscle tissue development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990359", "l": "stress response to zinc ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a zinc ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0070482", "l": "response to oxygen levels", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009099", "l": "valine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060758", "l": "foraging behavior by probing substrate", "d": ["Foraging behavior in which an anatomical part of the organism is inserted into the substrate to locate food."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990441", "l": "negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002004", "l": "secretion of vasopressin involved in fast regulation of systemic arterial blood pressure", "d": ["The regulated release of the hormone vasopressin into the blood stream by the hypothalamus and pituitary gland contributing to fast regulation of blood pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903859", "l": "regulation of dendrite extension", "d": ["Any process that modulates the frequency, rate or extent of dendrite extension."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0043144", "l": "sno(s)RNA processing", "d": ["Any process involved in the conversion of a primary snoRNA family RNA transcript into a mature snoRNA (eukaryota) or sRNA (archaea)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0048706", "l": "embryonic skeletal system development", "d": ["The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036529", "l": "protein deglycation, glyoxal removal", "d": ["The removal of glyoxal from a glycated protein, to form glycolate and a deglycated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009992", "l": "intracellular water homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of water within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019468", "l": "nopaline catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nopaline (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903623", "l": "negative regulation of RNA polymerase III activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase III activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900811", "l": "helvolic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of helvolic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903102", "l": "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904520", "l": "regulation of myofibroblast cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of myofibroblast cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.879406879579491", "identifiers": [{"i": "GO:0052173", "l": "response to defenses of other organism", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0120322", "l": "lipid modification by small protein conjugation", "d": ["A lipid modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target lipid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904992", "l": "positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000717", "l": "nucleotide-excision repair, DNA duplex unwinding", "d": ["The unwinding, or local denaturation, of the DNA duplex to create a bubble around the site of the DNA damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903002", "l": "positive regulation of lipid transport across blood-brain barrier", "d": ["Any process that activates or increases the frequency, rate or extent of lipid transport across blood-brain barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.282684029872676", "identifiers": [{"i": "GO:0009894", "l": "regulation of catabolic process", "d": ["Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048323", "l": "axial mesodermal cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030050", "l": "vesicle transport along actin filament", "d": ["Movement of a vesicle along an actin filament, mediated by motor proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007425", "l": "epithelial cell fate determination, open tracheal system", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into an epithelial cell within an open tracheal system regardless of its environment; upon determination, the cell fate cannot be reversed. Tracheal cells are set aside as 10 clusters of approximately 80 cells on each side of the embryo (termed tracheal placodes). An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901351", "l": "regulation of phosphatidylglycerol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylglycerol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036288", "l": "response to ximelagatran", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ximelagatran stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901058", "l": "p-hydroxyphenyl lignin metabolic process", "d": ["The chemical reactions and pathways involving p-hydroxyphenyl lignin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0001887", "l": "selenium compound metabolic process", "d": ["The chemical reactions and pathways involving compounds that contain selenium, such as selenocysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044859", "l": "protein insertion into plasma membrane raft", "d": ["The process in which a protein is incorporated into a plasma membrane raft."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901364", "l": "funalenone metabolic process", "d": ["The chemical reactions and pathways involving funalenone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010777", "l": "meiotic mismatch repair involved in reciprocal meiotic recombination", "d": ["A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902090", "l": "regulation of fumagillin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of fumagillin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018885", "l": "carbon tetrachloride metabolic process", "d": ["The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.651613913496419", "identifiers": [{"i": "GO:0021602", "l": "cranial nerve morphogenesis", "d": ["The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060619", "l": "cell migration involved in mammary placode formation", "d": ["The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071287", "l": "cellular response to manganese ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030703", "l": "eggshell formation", "d": ["Construction of the eggshell, a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051096", "l": "positive regulation of helicase activity", "d": ["Any process that activates or increases the activity of a helicase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904368", "l": "regulation of sclerenchyma cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of sclerenchyma cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0035891", "l": "exit from host cell", "d": ["The movement of an organism out of a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097318", "l": "invasive growth in response to abiotic stimulus", "d": ["The growth of colonies in filamentous chains of cells as a result of a abiotic stimulus. An example of this process is found in Candida albicans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990878", "l": "cellular response to gastrin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0042481", "l": "regulation of odontogenesis", "d": ["Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902364", "l": "negative regulation of protein localization to spindle pole body", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903647", "l": "negative regulation of chlorophyll catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061196", "l": "fungiform papilla development", "d": ["The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019392", "l": "glucarate metabolic process", "d": ["The chemical reactions and pathways involving glucarate, the dianion of glucaric acid, an aldaric acid derived from either glucose or gulose. There are two enantiomers L- and D-glucarate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033634", "l": "positive regulation of cell-cell adhesion mediated by integrin", "d": ["Any process that activates or increases the frequency, rate, or extent of cell-cell adhesion mediated by integrin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900946", "l": "positive regulation of isoprene metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of isoprene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000269", "l": "regulation of fibroblast apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of fibroblast apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002622", "l": "regulation of B cell antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035191", "l": "nuclear axial expansion", "d": ["The stepwise asymmetric spreading out of nuclei internally along the anterior-posterior axis of the developing insect embryo during mitotic cycles 4 to 6. This movement leads to the distribution of nuclei in a hollow ellipsoid underlying the cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072721", "l": "cellular response to dithiothreitol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0043634", "l": "polyadenylation-dependent ncRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032600", "l": "chemokine receptor transport out of membrane raft", "d": ["The directed movement of a chemokine receptor out of a membrane raft."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001261", "l": "negative regulation of semaphorin-plexin signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of semaphorin-plexin signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090367", "l": "negative regulation of mRNA modification", "d": ["Any process that decreases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0086003", "l": "cardiac muscle cell contraction", "d": ["The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a cardiac muscle cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010146", "l": "fructan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fructan a polysaccharide consisting of fructose residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042039", "l": "vanadium incorporation into metallo-sulfur cluster", "d": ["The incorporation of vanadium a metallo-sulfur cluster such as VFe(7-8)S(n)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044519", "l": "envenomation resulting in modulation of vasoactive intestinal polypeptide receptor activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000961", "l": "negative regulation of cellooligosaccharide metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902844", "l": "positive regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway", "d": ["A negative regulation of canonical Wnt signaling pathway that results in positive regulation of spinal cord association neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046004", "l": "positive regulation of syncytial blastoderm mitotic cell cycle", "d": ["Any process that activates or increases the rate or extent of progression through the syncytial blastoderm mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070374", "l": "positive regulation of ERK1 and ERK2 cascade", "d": ["Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.503963827996756", "identifiers": [{"i": "GO:0046530", "l": "photoreceptor cell differentiation", "d": ["The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097533", "l": "cellular stress response to acid chemical", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048170", "l": "positive regulation of long-term neuronal synaptic plasticity", "d": ["A process that increases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0071025", "l": "RNA surveillance", "d": ["A process that identifies and degrades defective or aberrant RNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010306", "l": "rhamnogalacturonan II biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of rhamnogalacturonan II, a low molecular mass (5 - 10KDa) pectic polysaccharide, conserved in the primary walls of dicotyledenous and monocotyledenous plants and gymnosperms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0089703", "l": "L-aspartate transmembrane export from vacuole", "d": ["The directed movement of L-aspartate out of the vacuole, across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150190", "l": "negative regulation of interleukin-32 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-32 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0035287", "l": "head segmentation", "d": ["Partitioning the insect head anlage into a fixed number of segmental units. The number of segments composing the insect head has long been a subject of debate, but it is generally agreed that there are 6 or 7 segments. From anterior to posterior the head segments are the procephalic segments (labral, (ocular), antennal and intercalary) and the gnathal segments (mandibular, maxillary and labial)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0002118", "l": "aggressive behavior", "d": ["A behavioral interaction between organisms in which one organism has the intention of inflicting physical damage on another individual."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071700", "l": "olfactory placode maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902733", "l": "regulation of growth plate cartilage chondrocyte differentiation", "d": ["Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904968", "l": "positive regulation of monopolar spindle attachment to meiosis I kinetochore", "d": ["Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0006808", "l": "regulation of nitrogen utilization", "d": ["Any process that modulates the frequency, rate or extent of nitrogen utilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.008356884950679", "identifiers": [{"i": "GO:0009991", "l": "response to extracellular stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0000122", "l": "negative regulation of transcription by RNA polymerase II", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085030", "l": "symbiotic process benefiting host", "d": ["A process carried out by symbiont gene products that enables a symbiotic interaction with a host organism, that is beneficial to the host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019123", "l": "peptidyl-methionine racemization", "d": ["The racemization of peptidyl-methionine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903721", "l": "positive regulation of I-kappaB phosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of I-kappaB phosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071505", "l": "response to mycophenolic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050676", "l": "negative regulation of urothelial cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of urothelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042077", "l": "protein phosphate-linked glycosylation via serine", "d": ["The glycosylation of peptidyl-serine through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905751", "l": "positive regulation of endosome to plasma membrane protein transport", "d": ["Any process that activates or increases the frequency, rate or extent of endosome to plasma membrane protein transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003296", "l": "apoptotic process involved in atrial ventricular junction remodeling", "d": ["Any apoptotic process that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.594043123901756", "identifiers": [{"i": "GO:0046164", "l": "alcohol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0090693", "l": "plant organ senescence", "d": ["A plant organ developmental process during which a plant dismantles cellular components to reclaim the cellular building blocks and nutrients that have been deposited in the plant organs during growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "34.014782413652306", "identifiers": [{"i": "GO:0050877", "l": "nervous system process", "d": ["A organ system process carried out by any of the organs or tissues of neurological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046311", "l": "prenylcysteine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061390", "l": "positive regulation of direction of cell growth", "d": ["Any process that increases the direction of cell growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035228", "l": "negative regulation of glutamate-cysteine ligase activity", "d": ["Any process that stops or reduces the activity of the enzyme glutamate-cysteine ligase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043577", "l": "chemotropism", "d": ["The movement of an organism, or part of an organism, in response to an external chemical gradient, usually toward or away from it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046039", "l": "GTP metabolic process", "d": ["The chemical reactions and pathways involving GTP, guanosine triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001264", "l": "negative regulation of C-C chemokine binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120117", "l": "T cell meandering migration", "d": ["The random-like motility observed for T cells in lymph nodes which enhances surveillance of antigens presented by major histocompatibility complex (MHC) molecules on antigen presenting cells (APCs)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051544", "l": "positive regulation of elastin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000312", "l": "regulation of kainate selective glutamate receptor activity", "d": ["Any process that modulates the frequency, rate or extent of kainate selective glutamate receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.506234140084757", "identifiers": [{"i": "GO:0034101", "l": "erythrocyte homeostasis", "d": ["Any process of regulating the production and elimination of erythrocytes within an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901954", "l": "regulation of retrograde dense core granule transport", "d": ["Any process that modulates the frequency, rate or extent of retrograde dense core granule transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046687", "l": "response to chromate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070370", "l": "cellular heat acclimation", "d": ["Any process that increases heat tolerance of a cell in response to high temperatures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099001", "l": "viral genome ejection through host cell envelope, long flexible tail mechanism", "d": ["Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a long, flexible tail ejection system consisting a baseplate, a central tube and a terminator complex which attaches the tail to the phage capsid. Upon binding to the host cell surface, the baseplate changes its conformation and triggers genome ejection into the host cell cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.06379513530257", "identifiers": [{"i": "GO:0006605", "l": "protein targeting", "d": ["The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010684", "l": "tricyclic triterpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071525", "l": "pyrrolysine metabolic process", "d": ["The chemical reactions and pathways involving pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902986", "l": "regulation of lysine biosynthetic process via aminoadipic acid", "d": ["Any process that modulates the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901788", "l": "benzoyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of benzoyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032342", "l": "aldosterone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060762", "l": "regulation of branching involved in mammary gland duct morphogenesis", "d": ["Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:1901463", "l": "regulation of tetrapyrrole biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018251", "l": "peptidyl-tyrosine dehydrogenation", "d": ["The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-dehydrotyrosine coupled with cyclization of neighboring residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904184", "l": "positive regulation of pyruvate dehydrogenase activity", "d": ["Any process that activates or increases the frequency, rate or extent of pyruvate dehydrogenase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0044458", "l": "motile cilium assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a motile cilium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043162", "l": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018967", "l": "tetrachloroethylene metabolic process", "d": ["The chemical reactions and pathways involving tetrachloroethylene (tetrachloroethene), a derivative of ethene with the hydrogen atoms replaced by chlorines. Tetrachloroethene has been used primarily as a solvent in dry-cleaning industries and to a lesser extent as a degreasing solvent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0051875", "l": "pigment granule localization", "d": ["Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071300", "l": "cellular response to retinoic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046382", "l": "GDP-D-rhamnose metabolic process", "d": ["The chemical reactions and pathways involving GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035964", "l": "COPI-coated vesicle budding", "d": ["The evagination of a Golgi membrane, resulting in formation of a COPI-coated vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900060", "l": "negative regulation of ceramide biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071994", "l": "phytochelatin transmembrane transport", "d": ["The process in which a phytochelatin is transported across a membrane. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905212", "l": "positive regulation of fibroblast chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of fibroblast chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052084", "l": "modulation by symbiont of host ethylene-mediated defense response", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140530", "l": "MCM complex loading", "d": ["The protein localization process in which two MCM complexes become associated with chromatin at replication origins. MCM loading begins when origin-bound ORC and Cdc6 (Cdc18 in fission yeast) recruit one MCM2-7/Cdt1 complex to the origin, includes formation of a succession of intermediate complexes and ATP hydrolysis-dependent Mcm2-7 ring closure, and ends when two MCM hexamers fully encircle DNA, and are oriented head-to-head. The double hexamer is inactive for DNA unwinding. MCM loading takes place during G1 phase, and precedes CMG complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090656", "l": "t-circle formation", "d": ["A telomere maintenance process that results in the formation of a telomeric circle, or t-circle. A t-circle is an extrachromosomal duplex or single-stranded circular DNA molecule composed of t-arrays. T-circles are involved in the control of telomere length via alternative-lengthening of telomeres (ALT) pathway and telomere rapid deletion (TRD)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990785", "l": "response to water-immersion restraint stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of water immersion while being held immobile."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902795", "l": "siRNA-mediated facultative heterochromatin formation", "d": ["The formation of facultative heterochromatin into a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process mediated by a small interfering RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901437", "l": "regulation of toluene metabolic process", "d": ["Any process that modulates the frequency, rate or extent of toluene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046226", "l": "coumarin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903722", "l": "regulation of centriole elongation", "d": ["Any process that modulates the frequency, rate or extent of centriole elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002048", "l": "pyoverdine metabolic process", "d": ["The chemical reactions and pathways involving the siderochrome pyoverdine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000985", "l": "positive regulation of ATP citrate synthase activity", "d": ["Any process that activates or increases the frequency, rate or extent of ATP citrate synthase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061816", "l": "proteaphagy", "d": ["The selective autophagy process that clears 26S proteasomes; homeostatic mechanism within the ubiquitin system that modulates proteolytic capacity and eliminates damaged particles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0002026", "l": "regulation of the force of heart contraction", "d": ["Any process that modulates the extent of heart contraction, changing the force with which blood is propelled."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0043981", "l": "histone H4-K5 acetylation", "d": ["The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090193", "l": "positive regulation of glomerulus development", "d": ["Any process that increases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010954", "l": "positive regulation of protein processing", "d": ["Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:0050885", "l": "neuromuscular process controlling balance", "d": ["Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032208", "l": "negative regulation of telomere maintenance via recombination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.744066580938323", "identifiers": [{"i": "GO:1905508", "l": "protein localization to microtubule organizing center", "d": ["A process in which a protein is transported to, or maintained in, a location within a microtubule organizing center."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035836", "l": "ergot alkaloid metabolic process", "d": ["The chemical reactions and pathways involving an ergot alkaloid, an indole alkaloid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010055", "l": "atrichoblast differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an atrichoblast, a root epidermal cell that will not give rise to a root hair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032775", "l": "DNA methylation on adenine", "d": ["The covalent transfer of a methyl group to N-6 of adenine in a DNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900360", "l": "regulation of pentasaccharide transport", "d": ["Any process that modulates the frequency, rate or extent of pentasaccharide transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901874", "l": "negative regulation of post-translational protein modification", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of post-translational protein modification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018899", "l": "1,2-dichloroethane metabolic process", "d": ["The chemical reactions and pathways involving 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904053", "l": "positive regulation of protein targeting to vacuole involved in autophagy", "d": ["Any process that activates or increases the frequency, rate or extent of protein targeting to vacuole involved in autophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0034635", "l": "glutathione transport", "d": ["The directed movement of glutathione, the tripeptide glutamylcysteinylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900809", "l": "fumigaclavine C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fumigaclavine C, a fungal ergot alkaloid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0043379", "l": "memory T cell differentiation", "d": ["The process in which a newly activated T cell acquires specialized features of a memory T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009662", "l": "etioplast organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an etioplast. An etioplast is a plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046847", "l": "filopodium assembly", "d": ["The assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033379", "l": "maintenance of protease location in T cell secretory granule", "d": ["A process in which a protease is maintained in a secretory granule in a T cell and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006005", "l": "L-fucose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-fucose (6-deoxy-L-galactose)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902758", "l": "bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of bis(molybdopterin guanine dinucleotide)molybdenum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000655", "l": "negative regulation of cellular response to testosterone stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to testosterone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0044646", "l": "envenomation resulting in modulation of complement activation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation in the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904810", "l": "negative regulation of dense core granule transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071544", "l": "diphosphoinositol polyphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0003230", "l": "cardiac atrium development", "d": ["The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0042244", "l": "spore wall assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a spore wall; a spore wall is the specialized envelope lying outside the cell membrane of a spore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990884", "l": "RNA acetylation", "d": ["The posttranscriptional addition of one or more acetyl groups to specific residues in an RNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002608", "l": "negative regulation of myeloid dendritic cell antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090680", "l": "viral release via disruption of host outer membrane", "d": ["The dissemination of mature viral particles from a host cell via the destabilization of the cell outer membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0048678", "l": "response to axon injury", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021958", "l": "gracilis tract morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the gracilis tract, a group of axons that are from neurons involved in proprioception from the lower trunk and lower limb."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032812", "l": "positive regulation of epinephrine secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0030225", "l": "macrophage differentiation", "d": ["The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902395", "l": "regulation of 1-deoxy-D-xylulose-5-phosphate synthase activity", "d": ["Any process that modulates the frequency, rate or extent of 1-deoxy-D-xylulose-5-phosphate synthase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010665", "l": "regulation of cardiac muscle cell apoptotic process", "d": ["Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.07563785880906", "identifiers": [{"i": "GO:0048592", "l": "eye morphogenesis", "d": ["The process in which the anatomical structures of the eye are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0016129", "l": "phytosteroid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071446", "l": "cellular response to salicylic acid stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900326", "l": "positive regulation of maltotriulose transport", "d": ["Any process that activates or increases the frequency, rate or extent of maltotriulose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000439", "l": "positive regulation of monocyte extravasation", "d": ["Any process that activates or increases the frequency, rate or extent of monocyte extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070617", "l": "negative regulation of thiamine diphosphate biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090245", "l": "axis elongation involved in somitogenesis", "d": ["The developmental growth that results in the elongation of the rostral-caudal axis that contributes to somitogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "48.814814537272589", "identifiers": [{"i": "GO:0048522", "l": "positive regulation of cellular process", "d": ["Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0003314", "l": "heart rudiment morphogenesis", "d": ["The process in which the anatomical structures of the heart rudiment are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006234", "l": "TTP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of TTP, ribosylthymine triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070581", "l": "rolling circle DNA replication", "d": ["A DNA-dependent DNA replication process in which a single-stranded DNA molecule is synthesized from a circular duplex template. Replication typically does not cease when one circumference has been replicated, but continues around the circumference several more times, producing a long single strand comprising multimers of the replicon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.264201259456904", "identifiers": [{"i": "GO:0032787", "l": "monocarboxylic acid metabolic process", "d": ["The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036287", "l": "response to iloperidone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iloperidone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007433", "l": "larval salivary gland boundary specification", "d": ["Determination in a larval organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051045", "l": "negative regulation of membrane protein ectodomain proteolysis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072075", "l": "metanephric mesenchyme development", "d": ["The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010206", "l": "photosystem II repair", "d": ["Proteolysis of the damaged D1 protein and re-assembly of a new D1 subunit in the photosystem II following photoinhibition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048246", "l": "macrophage chemotaxis", "d": ["The movement of a macrophage in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061127", "l": "negative regulation of positive chemotaxis to cAMP by DIF-1", "d": ["Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001980", "l": "regulation of systemic arterial blood pressure by ischemic conditions", "d": ["The process that modulates blood pressure by the detection of carbon dioxide levels in the brain stem. Increased levels activate the sympathetic vasoconstrictor mechanism increasing the force with which blood flows through the circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904417", "l": "positive regulation of xenophagy", "d": ["Any process that activates or increases the frequency, rate or extent of xenophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048346", "l": "positive regulation of paraxial mesodermal cell fate determination", "d": ["Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000706", "l": "meiotic DNA double-strand break processing", "d": ["The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904634", "l": "negative regulation of podocyte apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051454", "l": "intracellular pH elevation", "d": ["Any process that increases the internal pH of a cell, measured by the concentration of the hydrogen ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043317", "l": "regulation of cytotoxic T cell degranulation", "d": ["Any process that modulates the frequency, rate, or extent of cytotoxic T cell degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:1902905", "l": "positive regulation of supramolecular fiber organization", "d": ["Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046350", "l": "galactosaminoglycan metabolic process", "d": ["The chemical reactions and pathways involving galactosaminoglycans, any one of a group of polysaccharides that contain amino sugars derived from the galactose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0048069", "l": "eye pigmentation", "d": ["Establishment of a pattern of pigment in the eye of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0032271", "l": "regulation of protein polymerization", "d": ["Any process that modulates the frequency, rate or extent of the process of creating protein polymers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001126", "l": "positive regulation of translational frameshifting", "d": ["Any process that activates or increases the frequency, rate or extent of translational frameshifting."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:1904375", "l": "regulation of protein localization to cell periphery", "d": ["Any process that modulates the frequency, rate or extent of protein localization to cell periphery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010125", "l": "mycothiol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:1901071", "l": "glucosamine-containing compound metabolic process", "d": ["The chemical reactions and pathways involving glucosamine-containing compounds (glucosamines)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014836", "l": "myoblast fate commitment involved in skeletal muscle regeneration", "d": ["The process in which the developmental fate of a satellite cell becomes restricted such that it will develop into a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018003", "l": "peptidyl-lysine N6-acetylation", "d": ["The acetylation of the peptidyl-lysine of proteins to form the derivative peptidyl-N6-acetyl-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1905048", "l": "regulation of metallopeptidase activity", "d": ["Any process that modulates the frequency, rate or extent of metallopeptidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904094", "l": "positive regulation of autophagic cell death", "d": ["Any process that activates or increases the frequency, rate or extent of autophagic cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:1903318", "l": "negative regulation of protein maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051611", "l": "regulation of serotonin uptake", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of the monoamine neurotransmitter serotonin into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071030", "l": "nuclear mRNA surveillance of spliceosomal pre-mRNA splicing", "d": ["The set of processes involved in identifying and degrading incorrectly spliced pre-mRNAs within the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014817", "l": "skeletal muscle satellite cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009189", "l": "deoxyribonucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018341", "l": "peptidyl-lysine modification to peptidyl-N6-pyruvic acid 2-iminyl-L-lysine", "d": ["The modification of peptidyl-lysine to form peptidyl-N6-pyruvic acid 2-iminyl-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0001881", "l": "receptor recycling", "d": ["The process that results in the return of receptor molecules to an active state and an active cellular location after they have been stimulated by a ligand. An active state is when the receptor is ready to receive a signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046495", "l": "nicotinamide riboside metabolic process", "d": ["The chemical reactions and pathways involving nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001190", "l": "positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell", "d": ["Any process that activates or increases the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0007113", "l": "endomitotic cell cycle", "d": ["A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003272", "l": "endocardial cushion formation", "d": ["The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904172", "l": "positive regulation of bleb assembly", "d": ["Any process that activates or increases the frequency, rate or extent of bleb assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0002343", "l": "peripheral B cell selection", "d": ["Any B cell selection process that occurs in the periphery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902281", "l": "negative regulation of RNA helicase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent RNA helicase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060174", "l": "limb bud formation", "d": ["The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039705", "l": "viral translational readthrough", "d": ["The continuation of translation of a viral mRNA beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061249", "l": "mesonephric glomerular capillary formation", "d": ["The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019387", "l": "methanogenesis, from methanol", "d": ["The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including methanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990575", "l": "mitochondrial L-ornithine transmembrane transport", "d": ["The process in which L-ornithine is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042635", "l": "positive regulation of hair cycle", "d": ["Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031274", "l": "positive regulation of pseudopodium assembly", "d": ["Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061152", "l": "trachea submucosa development", "d": ["The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903673", "l": "mitotic cleavage furrow formation", "d": ["Any cleavage furrow formation that is involved in mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034302", "l": "akinete formation", "d": ["The process in which an akinete, a thick-walled (encysted) dormant cell derived from the enlargement of a vegetative cell, is formed. Akinetes typically have granular cytoplasm, are more resistant to environmental extremes than vegetative cells, and are characteristic of several groups of Cyanobacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901455", "l": "negative regulation of response to toluene", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to toluene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097250", "l": "mitochondrial respirasome assembly", "d": ["The aggregation, arrangement and bonding together of a set of respiratory enzyme complexes of the mitochondrial inner membrane (including, for example, complex II, complex III, complex IV) to form a large supercomplex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046003", "l": "negative regulation of syncytial blastoderm mitotic cell cycle", "d": ["Any process that stops, prevents or reduces the rate or extent of progression through the syncytial blastoderm mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032492", "l": "detection of molecule of oomycetes origin", "d": ["The series of events in which a stimulus from a molecule of oomycetes origin is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0002468", "l": "dendritic cell antigen processing and presentation", "d": ["The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140023", "l": "tRNA adenosine deamination to inosine", "d": ["The removal of an amine group from an adenosine to produce inosine within a tRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032489", "l": "regulation of Cdc42 protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905906", "l": "regulation of amyloid fibril formation", "d": ["Any process that modulates the frequency, rate or extent of amyloid fibril formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001124", "l": "regulation of translational frameshifting", "d": ["Any process that modulates the frequency, rate or extent of translational frameshifting."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060907", "l": "positive regulation of macrophage cytokine production", "d": ["Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905082", "l": "regulation of mitochondrial translational elongation", "d": ["Any process that modulates the frequency, rate or extent of mitochondrial translational elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0060573", "l": "cell fate specification involved in pattern specification", "d": ["The process involved in the specification of the identity of a cell in a field of cells that is being instructed as to how to differentiate. Once specification has taken place, that cell will be committed to differentiate down a specific pathway if left in its normal environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098792", "l": "xenophagy", "d": ["The selective autophagy process in which a region of cytoplasm containing an intracellular pathogen or some part of an intracellular pathogen (e.g. viral capsid) is enclosed in a double membrane bound autophagosome, which then fuses with the lysosome leading to degradation of the contents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060766", "l": "negative regulation of androgen receptor signaling pathway", "d": ["Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060172", "l": "astral microtubule depolymerization", "d": ["The removal of tubulin heterodimers from one or both ends of an astral microtubule. An astral microtubule is any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043921", "l": "modulation by host of viral transcription", "d": ["Any process in which a host organism modulates the frequency, rate or extent of viral transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051569", "l": "regulation of histone H3-K4 methylation", "d": ["Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098886", "l": "modification of dendritic spine", "d": ["Any process that modifies the structure of a dendritic spine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904140", "l": "negative regulation of microglial cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.06379513530257", "identifiers": [{"i": "GO:0048563", "l": "post-embryonic animal organ morphogenesis", "d": ["Morphogenesis, during the post-embryonic phase, of an animal tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033030", "l": "negative regulation of neutrophil apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0032309", "l": "icosanoid secretion", "d": ["The controlled release of icosanoids, any of a group of C20 polyunsaturated fatty acids from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019652", "l": "lactate fermentation to propionate and acetate", "d": ["The anaerobic enzymatic conversion of lactate to propionate, concomitant with the oxidation of lactate to acetate and CO2 and yielding energy in the form of adenosine triphosphate (ATP)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902892", "l": "positive regulation of root hair elongation", "d": ["Any process that activates or increases the frequency, rate or extent of root hair elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140249", "l": "protein catabolic process at postsynapse", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904362", "l": "regulation of calcitonin secretion", "d": ["Any process that modulates the frequency, rate or extent of calcitonin secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.163904156342888", "identifiers": [{"i": "GO:0006812", "l": "monoatomic cation transport", "d": ["The directed movement of a monoatomic cation, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007415", "l": "defasciculation of motor neuron axon", "d": ["Separation of a motor axon away from a bundle of axons known as a fascicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0060219", "l": "camera-type eye photoreceptor cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1990772", "l": "substance P secretion", "d": ["The regulated release of substance P, a peptide hormone that is involved in neurotransmission, inflammation, and antimicrobial activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0086012", "l": "membrane depolarization during cardiac muscle cell action potential", "d": ["The process in which cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.850028330009977", "identifiers": [{"i": "GO:0046651", "l": "lymphocyte proliferation", "d": ["The expansion of a lymphocyte population by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0034310", "l": "primary alcohol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061047", "l": "positive regulation of branching involved in lung morphogenesis", "d": ["Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051457", "l": "maintenance of protein location in nucleus", "d": ["Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072750", "l": "cellular response to leptomycin B", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:1902778", "l": "response to alkane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.349985564227573", "identifiers": [{"i": "GO:0010647", "l": "positive regulation of cell communication", "d": ["Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140210", "l": "protein transport along microtubule to kinetochore", "d": ["Any process in which a protein is transported to the kinetochore along a microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904843", "l": "cellular response to nitroglycerin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035640", "l": "exploration behavior", "d": ["The specific behavior of an organism in response to a novel environment or stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016561", "l": "protein import into peroxisome matrix, translocation", "d": ["The process in which proteins are moved across the peroxisomal membrane into the matrix. It is likely that the peroxisome targeting sequence receptor remains associated with cargo proteins during translocation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0046271", "l": "phenylpropanoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aromatic derivatives of trans-cinnamic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900963", "l": "negative regulation of methanophenazine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000969", "l": "positive regulation of AMPA receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of AMPA selective glutamate receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902239", "l": "negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071323", "l": "cellular response to chitin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042750", "l": "hibernation", "d": ["Any process in which an organism enters and maintains a period of dormancy in which to pass the winter. It is characterized by narcosis and by sharp reduction in body temperature and metabolic activity and by a depression of vital signs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021929", "l": "stellate cell precursor proliferation", "d": ["The multiplication or reproduction of neuroblasts that will give rise to stellate cells. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050902", "l": "leukocyte adhesive activation", "d": ["The activation of loosely bound or rolling leukocytes by signals displayed on blood vessel endothelial cells, which is typically the second step in cellular extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001562", "l": "response to protozoan", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008612", "l": "peptidyl-lysine modification to peptidyl-hypusine", "d": ["The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905670", "l": "TORC2 complex disassembly", "d": ["The disaggregation of a TORC2 complex into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120076", "l": "negative regulation of endocardial cushion cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of endocardial cushion cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905799", "l": "regulation of intraciliary retrograde transport", "d": ["Any process that modulates the frequency, rate or extent of intraciliary retrograde transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035521", "l": "monoubiquitinated histone deubiquitination", "d": ["The removal of the ubiquitin group from a monoubiquitinated histone protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900409", "l": "positive regulation of cellular response to oxidative stress", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to oxidative stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042412", "l": "taurine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0046794", "l": "transport of virus", "d": ["The directed movement of a virus, or part of a virus, into, out of, or within a host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048776", "l": "negative regulation of leucophore differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of leucophore differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072575", "l": "epithelial cell proliferation involved in liver morphogenesis", "d": ["The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033614", "l": "chloroplast proton-transporting ATP synthase complex assembly", "d": ["The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the chloroplast thylakoid membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070342", "l": "brown fat cell proliferation", "d": ["The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061970", "l": "maintenance of right sidedness", "d": ["The organization process that preserves the right sidedness in an organism's body plan or part of an organism with respect to the left and right halves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090104", "l": "pancreatic epsilon cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic epsilon cell. A pancreatic epsilon cell is a cell in the pancreas that secretes ghrelin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003262", "l": "endocardial progenitor cell migration to the midline involved in heart field formation", "d": ["The orderly movement of an endocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into endocardial cells of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032078", "l": "negative regulation of endodeoxyribonuclease activity", "d": ["Any process that stops or reduces the rate of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900025", "l": "negative regulation of substrate adhesion-dependent cell spreading", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of substrate adhesion-dependent cell spreading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003114", "l": "positive regulation of heart rate by circulating norepinephrine", "d": ["The process in which the secretion of norepinephrine into the bloodstream increases the rate of heart muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0006772", "l": "thiamine metabolic process", "d": ["The chemical reactions and pathways involving thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0048439", "l": "flower morphogenesis", "d": ["The process in which the anatomical structures of the flower are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.356779217613806", "identifiers": [{"i": "GO:0071826", "l": "protein-RNA complex organization", "d": ["Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002606", "l": "positive regulation of dendritic cell antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062123", "l": "regulation of linear element maturation", "d": ["Any process that modulates the rate, frequency or extent of linear element maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045007", "l": "depurination", "d": ["The disruption of the bond between the sugar in the backbone and the A or G base, causing the base to be removed and leaving a depurinated sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0052316", "l": "phytoalexin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phytoalexins, any of a range of substances produced by plants as part of their defense response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0033619", "l": "membrane protein proteolysis", "d": ["The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060610", "l": "mesenchymal cell differentiation involved in mammary gland development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000863", "l": "positive regulation of estrogen secretion", "d": ["Any process that activates or increases the frequency, rate or extent of estrogen secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044484", "l": "envenomation resulting in fibrinolysis in another organism", "d": ["The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinolysis, a process that solubilizes fibrin, chiefly by the proteolytic action of plasmin, in the bloodstream of the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000698", "l": "positive regulation of epithelial cell differentiation involved in kidney development", "d": ["Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098941", "l": "anterograde trans-synaptic signaling by trans-synaptic protein complex", "d": ["Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by a trans-synaptic protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080064", "l": "4,4-dimethyl-9beta,19-cyclopropylsterol oxidation", "d": ["A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4,4-dimethyl-9beta,19-cyclopropylsterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy, 4-beta-methyl-9beta,19-cyclopropylsterol + 3 NADP+ + 3 H2O."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900590", "l": "violaceol I biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of violaceol I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060315", "l": "negative regulation of ryanodine-sensitive calcium-release channel activity", "d": ["Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902970", "l": "premeiotic DNA replication DNA duplex unwinding", "d": ["Any DNA duplex unwinding involved in meiotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035544", "l": "negative regulation of SNARE complex assembly", "d": ["Any process that decreases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903226", "l": "positive regulation of endodermal cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021901", "l": "early neuron fate commitment in forebrain", "d": ["The commitment of neuroepithelial cell to become a neuron that will reside in the forebrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052786", "l": "alpha-linked polysaccharide catabolism to maltotriose", "d": ["The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltotriose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072135", "l": "kidney mesenchymal cell proliferation", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population in the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0001766", "l": "membrane raft polarization", "d": ["The clustering and aggregation of a membrane into domains. This serves as a mechanism to compartmentalize cellular activities and to establish cell polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900271", "l": "regulation of long-term synaptic potentiation", "d": ["Any process that modulates the frequency, rate or extent of long-term synaptic potentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.724229354797117", "identifiers": [{"i": "GO:2000241", "l": "regulation of reproductive process", "d": ["Any process that modulates the frequency, rate or extent of reproductive process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902176", "l": "negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034463", "l": "90S preribosome assembly", "d": ["The aggregation, arrangement and bonding together of proteins and RNA molecules to form a 90S preribosome. The 90S preribosome represents the complex that forms on the primary rRNA transcript before it splits into the small subunit and large subunit portions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060579", "l": "ventral spinal cord interneuron fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a ventral spinal cord interneuron. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043427", "l": "carbon fixation by 3-hydroxypropionate cycle", "d": ["An autotrophic carbon dioxide fixation pathway by which two molecules of carbon dioxide are fixed to form glyoxylate. Acetyl coenzyme A (acetyl-CoA) is assumed to be converted to malate, and two CO2 molecules are thereby fixed. Malyl-CoA is thought to be cleaved to acetyl-CoA, the starting molecule, and glyoxylate, the carbon fixation product."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0048449", "l": "floral organ formation", "d": ["The process that gives rise to floral organs. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034298", "l": "arthrospore formation", "d": ["The formation of conidia by the conversion of a pre-existing hypha. An arthrospore is produced by the last cell on a hypha breaking off and dispersing. Usually the walls thicken and the cell(s) separates before swelling of each spore. Sometimes further septa form in each cell prior to disarticulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090109", "l": "regulation of cell-substrate junction assembly", "d": ["Any process that modulates the rate, frequency, or extent of cell-substrate junction assembly. Cell-substrate junction assembly is the aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901210", "l": "regulation of cardiac chamber formation", "d": ["Any process that modulates the frequency, rate or extent of cardiac chamber formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905310", "l": "regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075266", "l": "negative regulation of oogonium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039505", "l": "suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II", "d": ["Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class II protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.000891501185137", "identifiers": [{"i": "GO:0021545", "l": "cranial nerve development", "d": ["The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032538", "l": "regulation of host-seeking behavior", "d": ["Any process that modulates the frequency, rate or extent of any behavior associated with finding a host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900616", "l": "emericellamide A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of emericellamide A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002665", "l": "negative regulation of T cell tolerance induction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140479", "l": "ergothioneine biosynthesis from histidine via hercynylcysteine sulfoxide synthase", "d": ["A biosynthetic process that results in the formation of ergothioneine from histidine via a set of steps including the hercynylcysteine sulfoxide synthase reaction, which converts N-alpha,N-alpha,N-alpha-trimethyl-L-histidine directly to hercynylcysteine sulfoxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0003281", "l": "ventricular septum development", "d": ["The progression of the ventricular septum over time from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901482", "l": "L-lysine import into vacuole involved in cellular response to nitrogen starvation", "d": ["A L-lysine import into the vacuole that is involved in cellular response to nitrogen starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051876", "l": "pigment granule dispersal", "d": ["The directed movement of pigment granules within a cell towards the cell periphery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0050709", "l": "negative regulation of protein secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1990700", "l": "nucleolar chromatin organization", "d": ["Any process that results in the specification, formation or maintenance of the physical structure of nucleolar chromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0099517", "l": "synaptic vesicle transport along microtubule", "d": ["The directed movement of synaptic vesicles along microtubules within a cell, powered by molecular motors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048543", "l": "phytochrome chromophore biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the phytochrome chromophore. The phytochrome chromophore is a linear tetrapyrrolic prosthetic group covalently attached to the large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far red light absorbing form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905230", "l": "response to borneol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001172", "l": "positive regulation of glycolytic fermentation to ethanol", "d": ["Any process that activates or increases the frequency, rate or extent of glucose catabolic process to ethanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905211", "l": "negative regulation of fibroblast chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051127", "l": "positive regulation of actin nucleation", "d": ["Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900408", "l": "negative regulation of cellular response to oxidative stress", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0046886", "l": "positive regulation of hormone biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032650", "l": "regulation of interleukin-1 alpha production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-1 alpha production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120008", "l": "positive regulation of glutamatergic neuron differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140914", "l": "zinc ion import into secretory vesicle", "d": ["The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a secretory vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006219", "l": "deoxyuridine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002795", "l": "negative regulation of antimicrobial peptide secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007509", "l": "mesoderm migration involved in gastrulation", "d": ["The migration of mesodermal cells during gastrulation to help establish the multilayered body plan of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903066", "l": "regulation of protein localization to cell tip", "d": ["Any process that modulates the frequency, rate or extent of protein localization to cell tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070958", "l": "negative regulation of neutrophil mediated killing of gram-positive bacterium", "d": ["Any process that decreases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010069", "l": "zygote asymmetric cytokinesis in embryo sac", "d": ["The division of the zygote in a plane perpendicular to the long axis of the embryo sac to produce a larger basal cell near the micropyle and a small terminal cell close to what was the central cell and is now the developing endosperm. An example of this process is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.261443428098588", "identifiers": [{"i": "GO:0086065", "l": "cell communication involved in cardiac conduction", "d": ["Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044098", "l": "DNA secretion by the type IV secretion system", "d": ["The controlled release of DNA by a cell, via the type IV secretion system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033534", "l": "verbascose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904134", "l": "negative regulation of convergent extension involved in rhombomere morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030994", "l": "primary cell septum disassembly", "d": ["Dissolution of the primary septum during cell separation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901104", "l": "tetracenomycin C metabolic process", "d": ["The chemical reactions and pathways involving tetracenomycin C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034165", "l": "positive regulation of toll-like receptor 9 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.482821972649937", "identifiers": [{"i": "GO:0006935", "l": "chemotaxis", "d": ["The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:1903170", "l": "negative regulation of calcium ion transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030034", "l": "microvillar actin bundle assembly", "d": ["Assembly of the parallel bundle of actin filaments at the core of a microvillus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015956", "l": "bis(5'-nucleosidyl) oligophosphate metabolic process", "d": ["The chemical reactions and pathways involving a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070921", "l": "regulation of siRNA processing", "d": ["Any process that modulates the frequency, rate or extent of siRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:0072338", "l": "lactam metabolic process", "d": ["The chemical reactions and pathways involving lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0021873", "l": "forebrain neuroblast division", "d": ["The division of a neuroblast located in the forebrain. Neuroblast division gives rise to at least another neuroblast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018949", "l": "m-xylene metabolic process", "d": ["The chemical reactions and pathways involving m-xylene, (1,3-dimethylbenzene) a colorless, liquid aromatic hydrocarbon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1905208", "l": "negative regulation of cardiocyte differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001112", "l": "regulation of cellular response to hepatocyte growth factor stimulus", "d": ["Any process that modulates the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048198", "l": "Golgi vesicle bud deformation and release", "d": ["The process in which cytosolic coat proteins fit together in a basketlike convex framework to form a coated deformed region on the cytoplasmic surface of the membrane. The deformed region forms into a complete vesicle and is released."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060771", "l": "phyllotactic patterning", "d": ["The radial pattern formation process that results in the formation of plant organs (leaves or leaf-like structures) or flower primordia around a central axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0016188", "l": "synaptic vesicle maturation", "d": ["Steps required to form an initiated synaptic vesicle into a fully formed and transmissible synaptic vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990619", "l": "histone H3-K9 deacetylation", "d": ["The modification of histone H3 by the removal of an acetyl group from lysine at position 9 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.701260003289605", "identifiers": [{"i": "GO:0032412", "l": "regulation of monoatomic ion transmembrane transporter activity", "d": ["Any process that modulates the activity of an ion transporter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990787", "l": "negative regulation of hh target transcription factor activity", "d": ["Any process that decreases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates members of the Gli protein family are activated by Hedgehog signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090135", "l": "actin filament branching", "d": ["The formation of daughter actin filament branches at an angle on the sides of preexisting mother filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032973", "l": "amino acid export across plasma membrane", "d": ["The directed movement of amino acids from inside of a cell, across the plasma membrane and into the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0016241", "l": "regulation of macroautophagy", "d": ["Any process that modulates the frequency, rate or extent of macroautophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031412", "l": "gas vesicle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a gas vesicle. A gas vesicle is a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060098", "l": "membrane reorganization involved in phagocytosis, engulfment", "d": ["The assembly and arrangement of the plasma membrane that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060640", "l": "positive regulation of dentin-containing tooth bud formation by mesenchymal-epithelial signaling", "d": ["Any process that initiates the formation of a tooth bud by the secretion of a signal from a mesenchymal cell and its reception and subsequent change in the identity of an epithelial cell of the tooth bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902010", "l": "negative regulation of translation in response to endoplasmic reticulum stress", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045955", "l": "negative regulation of calcium ion-dependent exocytosis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of calcium ion-dependent exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048783", "l": "positive regulation of cyanophore differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of cyanophore differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071486", "l": "cellular response to high light intensity", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014720", "l": "tonic skeletal muscle contraction", "d": ["A process in which force is generated within tonic skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The tonic skeletal muscle is characterized by long lasting contractile responses and high resistance to fatigue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.644186068201407", "identifiers": [{"i": "GO:0042552", "l": "myelination", "d": ["The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072187", "l": "metanephric cap formation", "d": ["The developmental process pertaining to the initial formation of a metanephric cap from unspecified parts. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070073", "l": "clustering of voltage-gated calcium channels", "d": ["The process in which voltage-gated calcium channels become localized together in high densities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009711", "l": "purine alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072060", "l": "outer medullary collecting duct development", "d": ["The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0080053", "l": "response to phenylalanine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900834", "l": "regulation of emericellin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of emericellin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010540", "l": "basipetal auxin transport", "d": ["The unidirectional movement of auxin from the apex to base of an organ, including the shoot, leaf, primary root, or lateral root."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043507", "l": "positive regulation of JUN kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of JUN kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032874", "l": "positive regulation of stress-activated MAPK cascade", "d": ["Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003051", "l": "angiotensin-mediated drinking behavior", "d": ["The drinking behavior that is mediated by the action of angiotensin in the brain. Angiotensin stimulates the brain centers that control thirst."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900359", "l": "positive regulation of nigerotriose transport", "d": ["Any process that activates or increases the frequency, rate or extent of nigerotriose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0002441", "l": "histamine secretion involved in inflammatory response", "d": ["The regulated release of histamine by a cell as part of an inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046784", "l": "viral mRNA export from host cell nucleus", "d": ["The directed movement of intronless viral mRNA from the host nucleus to the cytoplasm for translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0030436", "l": "asexual sporulation", "d": ["The formation of spores derived from the products of an asexual cell division. Examples of this process are found in bacteria and fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.187403162058388", "identifiers": [{"i": "GO:0008366", "l": "axon ensheathment", "d": ["Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0106071", "l": "positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006646", "l": "phosphatidylethanolamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903793", "l": "positive regulation of monoatomic anion transport", "d": ["Any process that activates or increases the frequency, rate or extent of anion transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0031345", "l": "negative regulation of cell projection organization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002291", "l": "T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell", "d": ["The change in morphology and behavior of a mature or immature T cell resulting from exposure to an antigen for which its T cell receptor is specific bound to an MHC molecule on an antigen presenting cell, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.506234140084757", "identifiers": [{"i": "GO:0044093", "l": "positive regulation of molecular function", "d": ["Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002787", "l": "negative regulation of antibacterial peptide production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900752", "l": "malonic acid transport", "d": ["The directed movement of a malonic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0086047", "l": "membrane depolarization during Purkinje myocyte cell action potential", "d": ["The process in which Purkinje myocyte membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0048865", "l": "stem cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a stem cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048380", "l": "negative regulation of lateral mesodermal cell fate specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009184", "l": "purine deoxyribonucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032757", "l": "positive regulation of interleukin-8 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-8 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098942", "l": "retrograde trans-synaptic signaling by trans-synaptic protein complex", "d": ["Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by trans-synaptic protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901781", "l": "p-cumate metabolic process", "d": ["The chemical reactions and pathways involving p-cumate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051355", "l": "proprioception involved in equilibrioception", "d": ["The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0030046", "l": "parallel actin filament bundle assembly", "d": ["Assembly of actin filament bundles in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902166", "l": "negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018426", "l": "O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine. The polypeptide backbones of glycoproteins and mucin-like proteoglycans are extensively modified with a complex array of phosphoglycan chains that are linked to Ser/Thr-rich domains via a common Man-alpha1-PO4-Ser linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019389", "l": "glucuronoside metabolic process", "d": ["The chemical reactions and pathways involving glucuronosides, any compound formed by combination in glycosidic linkage of a hydroxy compound with the anomeric carbon atom of a glucuronate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0019885", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class I", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018173", "l": "peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine", "d": ["The chemical reactions and pathways resulting in the formation of peptidyl-1-thioglycine from other compounds, including peptidyl-glycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000806", "l": "positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled", "d": ["Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072291", "l": "epithelial cell migration involved in metanephric distal tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to metanephric distal tubule morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002033", "l": "angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure", "d": ["The process that increases the diameter of a blood vessel via the renin-angiotensin system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0046459", "l": "short-chain fatty acid metabolic process", "d": ["The chemical reactions and pathways involving a fatty acid with an aliphatic tail of less than 6 carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0019760", "l": "glucosinolate metabolic process", "d": ["The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036090", "l": "cleavage furrow ingression", "d": ["Advancement of the cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000426", "l": "negative regulation of apoptotic cell clearance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic cell clearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905073", "l": "regulation of tight junction disassembly", "d": ["Any process that modulates the frequency, rate or extent of tight junction disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010691", "l": "negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels", "d": ["Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a stimulus reflecting the presence, absence, or concentration of nutrients."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904432", "l": "regulation of ferrous iron binding", "d": ["Any process that modulates the frequency, rate or extent of ferrous iron binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021678", "l": "third ventricle development", "d": ["The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001746", "l": "Bolwig's organ morphogenesis", "d": ["The morphogenetic process in which the anatomical structures of the larval eye in Drosophila are generated and organized. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0048821", "l": "erythrocyte development", "d": ["The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010360", "l": "negative regulation of anion channel activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035653", "l": "clathrin-coated vesicle cargo loading, AP-1-mediated", "d": ["Formation of a macromolecular complex between proteins of the AP-1 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. The AP-1 adaptor protein complex is a component of the cytoplasmic coat found on clathrin-coated vesicles, and binds to sorting signals of cargo to facilitate their trafficking."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0031129", "l": "inductive cell-cell signaling", "d": ["Signaling at short range between cells of different ancestry and developmental potential that results in one cell or group of cells effecting a developmental change in the other. This is often done by secretion of proteins by one cell which affects the neighboring cells and causes them to adopt a certain fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060582", "l": "cell fate determination involved in pattern specification", "d": ["A process involved in commitment of a cell to a fate in a developmental field. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072154", "l": "proximal convoluted tubule segment 1 cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into an S1 cell in the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.432445482536949", "identifiers": [{"i": "GO:1903532", "l": "positive regulation of secretion by cell", "d": ["Any process that activates or increases the frequency, rate or extent of secretion by cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030213", "l": "hyaluronan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007460", "l": "R8 cell fate commitment", "d": ["The process in which the R8 photoreceptor commits to its cell fate. The R8 receptor contributes the central part of the rhabdomere in the basal parts of the ommatidium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000388", "l": "positive regulation of antral ovarian follicle growth", "d": ["Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046396", "l": "D-galacturonate metabolic process", "d": ["The chemical reactions and pathways involving D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid. D-galacturonic acid is a component of plant gums and bacterial cell walls."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034268", "l": "discadenine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0098751", "l": "bone cell development", "d": ["The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990036", "l": "calcium ion import into sarcoplasmic reticulum", "d": ["The directed movement of calcium ions into a sarcoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072577", "l": "endothelial cell apoptotic process", "d": ["Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0046456", "l": "icosanoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034460", "l": "uropod assembly", "d": ["The assembly of a uropod by rearrangement of the cytoskeleton and overlying membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070638", "l": "pyridine nucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075302", "l": "regulation of basidiospore formation", "d": ["Any process that modulates the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi Basidiomycetes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032822", "l": "positive regulation of natural killer cell proliferation involved in immune response", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0097283", "l": "keratinocyte apoptotic process", "d": ["Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903140", "l": "regulation of establishment of endothelial barrier", "d": ["Any process that modulates the frequency, rate or extent of establishment of endothelial barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902204", "l": "positive regulation of hepatocyte growth factor receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000479", "l": "regulation of cAMP-dependent protein kinase activity", "d": ["Any process that modulates the frequency, rate or extent of cAMP-dependent protein kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.443919496911477", "identifiers": [{"i": "GO:0043010", "l": "camera-type eye development", "d": ["The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.757808809870852", "identifiers": [{"i": "GO:1901699", "l": "cellular response to nitrogen compound", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1904616", "l": "regulation of actin binding", "d": ["Any process that modulates the frequency, rate or extent of actin binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042361", "l": "menaquinone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of menaquinones, any of the quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0090042", "l": "tubulin deacetylation", "d": ["The removal of an acetyl group from tubulin. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0051503", "l": "adenine nucleotide transport", "d": ["The directed movement of adenine nucleotides, ATP, ADP, and/or AMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903268", "l": "positive regulation of ornithine catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of ornithine catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905100", "l": "regulation of apoptosome assembly", "d": ["Any process that modulates the frequency, rate or extent of apoptosome assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904027", "l": "negative regulation of collagen fibril organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900886", "l": "positive regulation of tridecane biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of tridecane biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900000", "l": "regulation of anthocyanin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of anthocyanin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032923", "l": "organic phosphonate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Synthesis of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043468", "l": "regulation of fucose catabolic process", "d": ["Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of fucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001927", "l": "exocyst assembly", "d": ["The aggregation, arrangement and bonding together of various polypeptides into the exocyst complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022021", "l": "caudal ganglionic eminence cell proliferation", "d": ["The multiplication or reproduction of caudal ganglionic eminence cells, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902245", "l": "cis-abienol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cis-abienol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.115164699299683", "identifiers": [{"i": "GO:0099124", "l": "axonal dopamine secretion", "d": ["The regulated release of dopamine from an axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0007628", "l": "adult walking behavior", "d": ["The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035610", "l": "protein side chain deglutamylation", "d": ["The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042671", "l": "retinal cone cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905365", "l": "regulation of intralumenal vesicle formation", "d": ["Any process that modulates the frequency, rate or extent of intralumenal vesicle formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039700", "l": "fusion of viral membrane with host outer nuclear membrane", "d": ["Fusion of a viral primary envelope with the host outer nuclear membrane during nuclear egress. The transitory primary envelope is acquired by the virus as it buds at the inner nuclear membrane and gains access to the perinuclear space. This membrane is lost by fusing with the host outer nuclear membrane during nuclear exit."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903599", "l": "positive regulation of autophagy of mitochondrion", "d": ["Any process that activates or increases the frequency, rate or extent of mitochondrion degradation by autophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:2000272", "l": "negative regulation of signaling receptor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045467", "l": "R7 cell development", "d": ["The process whose specific outcome is the progression of the R7 photoreceptor over time, from its formation to the mature structure. The R7 photoreceptor is the last photoreceptor to develop in the ommatidium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903644", "l": "regulation of chaperone-mediated protein folding", "d": ["Any process that modulates the frequency, rate or extent of chaperone-mediated protein folding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0080117", "l": "secondary growth", "d": ["Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of secondary vascular tissues by the vascular cambium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007419", "l": "ventral cord development", "d": ["The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019593", "l": "mannitol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901797", "l": "negative regulation of signal transduction by p53 class mediator", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction by p53 class mediator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048877", "l": "homeostasis of number of retina cells", "d": ["Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the retina."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0006534", "l": "cysteine metabolic process", "d": ["The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0000422", "l": "autophagy of mitochondrion", "d": ["The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902564", "l": "negative regulation of neutrophil activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902685", "l": "positive regulation of receptor localization to synapse", "d": ["Any process that activates or increases the frequency, rate or extent of receptor localization to synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900322", "l": "negative regulation of maltotetraose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maltotetraose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010714", "l": "positive regulation of collagen metabolic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0042133", "l": "neurotransmitter metabolic process", "d": ["The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904850", "l": "negative regulation of establishment of protein localization to telomere", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to telomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.824513090543306", "identifiers": [{"i": "GO:0006665", "l": "sphingolipid metabolic process", "d": ["The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060143", "l": "positive regulation of syncytium formation by plasma membrane fusion", "d": ["Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021931", "l": "rostral hindbrain neuronal precursor cell proliferation", "d": ["The multiplication or reproduction of neuroblasts that will give rise to neurons of the lateral pontine nucleus and the locus ceruleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904944", "l": "positive regulation of cardiac ventricle formation", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904109", "l": "positive regulation of cholesterol import", "d": ["Any process that activates or increases the frequency, rate or extent of cholesterol import."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.248384282929521", "identifiers": [{"i": "GO:0051493", "l": "regulation of cytoskeleton organization", "d": ["Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060812", "l": "orthodenticle mRNA localization", "d": ["Any process in which orthodenticle mRNA is transported to and maintained in the oocyte and/or syncytial embryo as part of the process that will specify the anterior/posterior axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072053", "l": "renal inner medulla development", "d": ["The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035906", "l": "descending aorta development", "d": ["The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015843", "l": "methylammonium transport", "d": ["The directed movement of methylammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051515", "l": "positive regulation of monopolar cell growth", "d": ["Any process that activates or increases the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060067", "l": "cervix development", "d": ["The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900724", "l": "positive regulation of protein adenylylation", "d": ["Any process that activates or increases the frequency, rate or extent of protein adenylylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.777964009505382", "identifiers": [{"i": "GO:0052572", "l": "response to host immune response", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046819", "l": "protein secretion by the type V secretion system", "d": ["The process in which proteins mediate their own secretion across the outer membrane through a beta-barrel pore structure formed by the C-terminal domain of the protein precursor. Following passage across the outer membrane, the mature protein is released from the pore by an autocatalytic activity. Proteins secreted by the Type V system are first translocated across the plasma membrane by the Sec pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0003084", "l": "positive regulation of systemic arterial blood pressure", "d": ["The process that increases the force with which blood travels through the systemic arterial circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0031100", "l": "animal organ regeneration", "d": ["The regrowth of a lost or destroyed animal organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090355", "l": "positive regulation of auxin metabolic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071828", "l": "apolipoprotein E recycling", "d": ["The process in which chylomicron remnant-associated apolipoprotein E is internalized by endocytosis, localized to recycling endosomes and then secreted in association with a high-density lipoprotein particle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002925", "l": "positive regulation of humoral immune response mediated by circulating immunoglobulin", "d": ["Any process that activates or increases the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904796", "l": "regulation of core promoter binding", "d": ["Any process that modulates the frequency, rate or extent of core promoter binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042711", "l": "maternal behavior", "d": ["Female behaviors associated with the care and rearing of offspring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1990736", "l": "regulation of vascular associated smooth muscle cell membrane depolarization", "d": ["Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a vascular smooth muscle cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0072224", "l": "metanephric glomerulus development", "d": ["The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "43.226712970641344", "identifiers": [{"i": "GO:0071840", "l": "cellular component organization or biogenesis", "d": ["A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0030222", "l": "eosinophil differentiation", "d": ["The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032334", "l": "inhibin secretion", "d": ["The regulated release of an inhibin, either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099149", "l": "regulation of postsynaptic neurotransmitter receptor internalization", "d": ["Any process that modulates the frequency, rate or extent of endocytosis of neurotransmitter receptor at the postsynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097430", "l": "copper ion import across prospore membrane", "d": ["The directed movement of copper ions from outside of a cell, across an ascospore-type prospore membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061332", "l": "Malpighian tubule bud morphogenesis", "d": ["The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901734", "l": "quercetin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of quercetin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048690", "l": "regulation of axon extension involved in regeneration", "d": ["Any process that modulates the frequency, rate or extent of axon extension involved in regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018163", "l": "protein-DNA covalent cross-linking via the 5'-end to peptidyl-tyrosine", "d": ["The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-DNA)-L-tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002082", "l": "regulation of oxidative phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031446", "l": "regulation of fast-twitch skeletal muscle fiber contraction", "d": ["Any process that modulates the frequency, rate or extent of fast-twitch skeletal muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.154928939654667", "identifiers": [{"i": "GO:0002819", "l": "regulation of adaptive immune response", "d": ["Any process that modulates the frequency, rate, or extent of an adaptive immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071948", "l": "activation-induced B cell apoptotic process", "d": ["B cell apoptotic process that occurs upon engagement of either the B cell receptor or CD40. Engagement of either receptor, but not both, leads to expression of fas or related receptors that make the B cell susceptible to fas-ligand mediated death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070666", "l": "regulation of mast cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of mast cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003392", "l": "cell adhesion involved in retrograde extension", "d": ["The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001732", "l": "formation of cytoplasmic translation initiation complex", "d": ["Joining of the large ribosomal subunit with the translation preinitiation complex, with release of IF2/eIF2 and IF3/eIF3 or IF5B/eIF5B. This leaves the functional ribosome at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010398", "l": "xylogalacturonan metabolic process", "d": ["The chemical reactions and pathways involving xylogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted on C-3 with beta-D-xylopyranose residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140076", "l": "negative regulation of lipoprotein transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lipoprotein transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003284", "l": "septum primum development", "d": ["The progression of the septum primum over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034585", "l": "21U-RNA metabolic process", "d": ["The chemical reactions and pathways involving 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098924", "l": "retrograde trans-synaptic signaling by nitric oxide", "d": ["Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030512", "l": "negative regulation of transforming growth factor beta receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015882", "l": "L-ascorbic acid transmembrane transport", "d": ["The process in which L-ascorbic acid is transported across a lipid bilayer, from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060989", "l": "lipid tube assembly involved in organelle fusion", "d": ["The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040033", "l": "sRNA-mediated gene silencing", "d": ["A post-transcriptional gene silencing pathway mediated by the action of small regulatory non-coding RNAs (sRNAs). sRNAs are 20-500 nucleotides in length and found in bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048092", "l": "negative regulation of male pigmentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in males."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0016243", "l": "regulation of autophagosome size", "d": ["Any process that modulates the size of the autophagosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904034", "l": "positive regulation of t-SNARE clustering", "d": ["Any process that activates or increases the frequency, rate or extent of t-SNARE clustering."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045697", "l": "regulation of synergid differentiation", "d": ["Any process that modulates the frequency, rate or extent of synergid cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902184", "l": "negative regulation of shoot apical meristem development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of shoot apical meristem development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097388", "l": "chemokine (C-C motif) ligand 19 production", "d": ["The appearance of chemokine (C-C motif) ligand 19 (CCL19) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0150202", "l": "negative regulation of transport across blood-brain barrier", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transport across blood-brain barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0061035", "l": "regulation of cartilage development", "d": ["Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060038", "l": "cardiac muscle cell proliferation", "d": ["The expansion of a cardiac muscle cell population by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0046620", "l": "regulation of organ growth", "d": ["Any process that modulates the frequency, rate or extent of growth of an organ of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048395", "l": "regulation of intermediate mesodermal cell fate determination", "d": ["Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051469", "l": "vesicle fusion with vacuole", "d": ["The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071793", "l": "bacillithiol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075248", "l": "regulation of aeciospore formation", "d": ["Any process that modulates the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098731", "l": "skeletal muscle satellite stem cell maintenance involved in skeletal muscle regeneration", "d": ["Any process by which the number of skeletal muscle satellite stem cells in a skeletal muscle is maintained during skeletal muscle regeneration. There are at least two mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072302", "l": "negative regulation of metanephric glomerular mesangial cell proliferation", "d": ["Any process that decreases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002032", "l": "desensitization of G protein-coupled receptor signaling pathway by arrestin", "d": ["The process that inhibits the signaling function of a G protein-coupled receptor by uncoupling the receptor from its downstream G proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902237", "l": "positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046102", "l": "inosine metabolic process", "d": ["The chemical reactions and pathways involving inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042784", "l": "evasion of host immune response via modulation of host complement system", "d": ["Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030648", "l": "aminoglycoside antibiotic biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.503963827996756", "identifiers": [{"i": "GO:1902903", "l": "regulation of supramolecular fiber organization", "d": ["Any process that modulates the frequency, rate or extent of supramolecular fiber organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030980", "l": "alpha-glucan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alpha-glucans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150052", "l": "regulation of postsynapse assembly", "d": ["Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010116", "l": "positive regulation of abscisic acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070600", "l": "fungal-type cell wall (1->3)-alpha-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002306", "l": "CD4-positive gamma-delta intraepithelial T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902076", "l": "regulation of lateral motor column neuron migration", "d": ["Any process that modulates the frequency, rate or extent of lateral motor column neuron migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0032888", "l": "regulation of mitotic spindle elongation", "d": ["Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070754", "l": "regulation of interleukin-35 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-35 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031272", "l": "regulation of pseudopodium assembly", "d": ["Any process that modulates the frequency, rate or extent of the assembly of pseudopodia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1990153", "l": "maintenance of protein localization to heterochromatin", "d": ["A process in which a protein is maintained in a location in telomeric heterochromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0018993", "l": "somatic sex determination", "d": ["The determination of sex and sexual phenotypes in an organism's soma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905736", "l": "negative regulation of L-proline import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-proline import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051335", "l": "meiosis II nuclear membrane reassembly", "d": ["The reformation of the nuclear membrane during meiosis II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060297", "l": "regulation of sarcomere organization", "d": ["Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901324", "l": "response to trichodermin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0060462", "l": "lung lobe development", "d": ["The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0031445", "l": "regulation of heterochromatin formation", "d": ["Any process that modulates the frequency, rate, extent or location of heterochromatin formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0050831", "l": "male-specific defense response to bacterium", "d": ["A set of reactions, specific to males, that are triggered in response to the presence of a bacterium that act to protect the cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061806", "l": "regulation of DNA recombination at centromere", "d": ["Any process that modulates the frequency, rate or extent of DNA recombination within centromeric DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034982", "l": "mitochondrial protein processing", "d": ["The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007367", "l": "segment polarity determination", "d": ["Division of the 14 parasegments of the embryo into anterior and posterior compartments; exemplified by the actions of the segment polarity gene products."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017192", "l": "N-terminal peptidyl-glutamine acetylation", "d": ["The acetylation of a glutamine residue in protein to form the N5-methyl-L-glutamine derivative. The occurrence of this modification has not been confirmed. Its annotation in sequence databases is either due to the misidentification of 2-pyrrolidone-5-carboxylic acid, or to inappropriate homolog comparisons when proteolytic modification is more probable."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0007338", "l": "single fertilization", "d": ["The union of male and female gametes to form a zygote."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075606", "l": "transport of viral material towards nucleus", "d": ["The directed movement of a virus, or part of a virus, towards the host cell nucleus. The process begins after viral entry, and ends when the viral material is at the nuclear membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900754", "l": "4-hydroxyphenylacetate transport", "d": ["The directed movement of a 4-hydroxyphenylacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009183", "l": "purine deoxyribonucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904198", "l": "negative regulation of regulation of vascular associated smooth muscle cell membrane depolarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061111", "l": "epithelial-mesenchymal cell signaling involved in lung development", "d": ["Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.741814295060699", "identifiers": [{"i": "GO:0044270", "l": "cellular nitrogen compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140075", "l": "regulation of lipoprotein transport", "d": ["Any process that controls lipoprotein transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0090148", "l": "membrane fission", "d": ["A process that is carried out at the cellular level which results in the separation of a single continuous membrane into two membranes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097466", "l": "ubiquitin-dependent glycoprotein ERAD pathway", "d": ["An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900242", "l": "regulation of synaptic vesicle endocytosis", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000659", "l": "regulation of interleukin-1-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of interleukin-1-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902924", "l": "poly(hydroxyalkanoate) biosynthetic process from glucose", "d": ["The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0001897", "l": "cytolysis by symbiont of host cells", "d": ["The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018881", "l": "bromoxynil metabolic process", "d": ["The chemical reactions and pathways involving bromoxynil, C7H3Br2NO, a dibrominated phenol derivative with a cyano (-CN) group attached. Bromoxynil is used as a herbicide for post-emergent control of annual broadleaf weeds and works by inhibiting photosynthesis in the target plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904718", "l": "negative regulation of AMPA glutamate receptor clustering", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor clustering."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.783030043623796", "identifiers": [{"i": "GO:1901292", "l": "nucleoside phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.362525179576039", "identifiers": [{"i": "GO:0072348", "l": "sulfur compound transport", "d": ["The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905115", "l": "regulation of lateral attachment of mitotic spindle microtubules to kinetochore", "d": ["Any process that modulates the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045128", "l": "negative regulation of reciprocal meiotic recombination", "d": ["Any process that decreases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0071375", "l": "cellular response to peptide hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045068", "l": "negative extrathymic T cell selection", "d": ["The process of elimination of extrathymically maturing T cells which react strongly with self-antigens."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901736", "l": "(R)-mevalonic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (R)-mevalonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033670", "l": "regulation of NAD+ kinase activity", "d": ["Any process that modulates the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0006523", "l": "alanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alanine, 2-aminopropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002315", "l": "marginal zone B cell differentiation", "d": ["The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051220", "l": "cytoplasmic sequestering of protein", "d": ["The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002807", "l": "positive regulation of antimicrobial peptide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.327400668044291", "identifiers": [{"i": "GO:1901991", "l": "negative regulation of mitotic cell cycle phase transition", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032953", "l": "regulation of (1->3)-beta-D-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0006067", "l": "ethanol metabolic process", "d": ["The chemical reactions and pathways involving ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000082", "l": "regulation of L-ascorbic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of L-ascorbic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071643", "l": "regulation of chemokine (C-C motif) ligand 4 production", "d": ["Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.651613913496419", "identifiers": [{"i": "GO:0120253", "l": "hydrocarbon catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a hydrocarbon, a compound consisting of carbon and hydrogen only."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007374", "l": "posterior midgut invagination", "d": ["Formation of a cup-shaped invagination at the posterior end of the embryo, bringing the posterior midgut and hindgut primordia into the interior."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007176", "l": "regulation of epidermal growth factor-activated receptor activity", "d": ["Any process that modulates the frequency, rate or extent of EGF-activated receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0007632", "l": "visual behavior", "d": ["The behavior of an organism in response to a visual stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0002885", "l": "positive regulation of hypersensitivity", "d": ["Any process that activates or increases the frequency, rate, or extent of hypersensitivity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0032241", "l": "positive regulation of nucleobase-containing compound transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021986", "l": "habenula development", "d": ["The progression of the habenula over time from its initial formation until its mature state. The habenula is the group of nuclei that makes up the stalk of the pineal gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0036212", "l": "contractile ring maintenance", "d": ["The process in which the contractile ring is maintained, typically in response to an internal or external cue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050837", "l": "peptide cross-linking via L-cysteinyl-L-selenocysteine", "d": ["The formation of a selenide-sulfide bond to form the cystine-like L-cysteinyl-L-selenocysteine, as in vertebrate selenopeptide P."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007366", "l": "periodic partitioning by pair rule gene", "d": ["Allocation of cells to parasegments in the embryo, through the action of overlapping series of pair rule gene activities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901173", "l": "phytoene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phytoene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900884", "l": "regulation of tridecane biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of tridecane biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0030416", "l": "methylamine metabolic process", "d": ["The chemical reactions and pathways involving methylamine (CH3NH2)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904891", "l": "positive regulation of excitatory synapse assembly", "d": ["Any process that activates or increases the frequency, rate or extent of excitatory synapse assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0071498", "l": "cellular response to fluid shear stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060448", "l": "dichotomous subdivision of terminal units involved in lung branching", "d": ["The process in which a lung bud bifurcates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.155424086811493", "identifiers": [{"i": "GO:0006970", "l": "response to osmotic stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021648", "l": "vestibulocochlear nerve morphogenesis", "d": ["The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009970", "l": "cellular response to sulfate starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043124", "l": "negative regulation of I-kappaB kinase/NF-kappaB signaling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075316", "l": "negative regulation of basidium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0003433", "l": "chondrocyte development involved in endochondral bone morphogenesis", "d": ["The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0020014", "l": "schizogony", "d": ["Cell division by multiple fission in which nuclei and other organelles in the parent cell divide repeatedly and move to the cell periphery before internal membranes develop around them, producing a large number of daughter cells simultaneously."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900421", "l": "positive regulation of cellular alcohol catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellular alcohol catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903671", "l": "negative regulation of sprouting angiogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sprouting angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031944", "l": "negative regulation of glucocorticoid metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903976", "l": "negative regulation of glial cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0075071", "l": "modulation by symbiont of host autophagy", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150022", "l": "apical dendrite development", "d": ["The process whose specific outcome is the progression of an apical dendrite over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903858", "l": "protein localization to old growing cell tip", "d": ["A process in which a protein is transported to, or maintained in, a location within an old growing cell tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001519", "l": "peptide amidation", "d": ["The posttranslational conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides. Occurs to over half of all peptide hormones to give bioactive peptides. This is a two step process catalyzed by a peptidyl-glycine alpha-hydroxylating monooxygenase and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase. In some organisms, this process is catalyzed by two separate enzymes, whereas in higher organisms, one polypeptide catalyzes both reactions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903940", "l": "negative regulation of TORC2 signaling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of TORC2 signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0090481", "l": "pyrimidine nucleotide-sugar transmembrane transport", "d": ["The process in which a pyrimidine nucleotide-sugar is transported across a membrane. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903459", "l": "mitotic DNA replication lagging strand elongation", "d": ["Any lagging strand elongation that is involved in mitotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0051923", "l": "sulfation", "d": ["The addition of a sulfate group to a molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072539", "l": "T-helper 17 cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 17 (Th17) cell. A Th17 cell is a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905205", "l": "positive regulation of connective tissue replacement", "d": ["Any process that activates or increases the frequency, rate or extent of connective tissue replacement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902640", "l": "propan-2-ol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of propan-2-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0072202", "l": "cell differentiation involved in metanephros development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019473", "l": "L-lysine catabolic process to glutarate, by acetylation", "d": ["The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including glutarate, by acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061195", "l": "taste bud formation", "d": ["The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.713784635685485", "identifiers": [{"i": "GO:0050870", "l": "positive regulation of T cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903446", "l": "geraniol metabolic process", "d": ["The chemical reactions and pathways involving geraniol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900507", "l": "negative regulation of iron-sulfur-molybdenum cofactor assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060024", "l": "rhythmic synaptic transmission", "d": ["Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0002515", "l": "B cell anergy", "d": ["Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:1903326", "l": "regulation of tRNA metabolic process", "d": ["Any process that modulates the frequency, rate or extent of tRNA metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001554", "l": "luteolysis", "d": ["The lysis or structural demise of the corpus luteum. During normal luteolysis, two closely related events occur. First, there is loss of the capacity to synthesize and secrete progesterone (functional luteolysis) followed by loss of the cells that comprise the corpus luteum (structural luteolysis). Preventing luteolysis is crucial to maintain pregnancy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048326", "l": "positive regulation of axial mesodermal cell fate determination", "d": ["Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0050730", "l": "regulation of peptidyl-tyrosine phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097324", "l": "melanocyte migration", "d": ["The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.503963827996756", "identifiers": [{"i": "GO:0002688", "l": "regulation of leukocyte chemotaxis", "d": ["Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0090504", "l": "epiboly", "d": ["The expansion of one cell sheet over other cells or yolk."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001317", "l": "kojic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of kojic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0007532", "l": "regulation of mating-type specific transcription, DNA-templated", "d": ["Any mating-type specific process that modulates the frequency, rate or extent of cellular DNA-templated transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0043133", "l": "hindgut contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070472", "l": "regulation of uterine smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of uterine smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001546", "l": "preantral ovarian follicle growth", "d": ["Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990938", "l": "peptidyl-aspartic acid autophosphorylation", "d": ["The phosphorylation by a protein of one or more of its own aspartate amino acid residues, or an aspartate residue on an identical protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045037", "l": "protein import into chloroplast stroma", "d": ["The targeting and import of proteins into the chloroplast stroma. Import depends on ATP hydrolysis catalyzed by stromal chaperones. Chloroplast stromal proteins, such as the S subunit of rubisco, have a N-terminal stromal-import sequence of about 44 amino acids which is cleaved from the protein precursor after import."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016261", "l": "selenocysteine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of selenocysteine, an essential component of glutathione peroxidase and some other proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900604", "l": "tensidol A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tensidol A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010482", "l": "regulation of epidermal cell division", "d": ["Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905485", "l": "positive regulation of motor neuron migration", "d": ["Any process that activates or increases the frequency, rate or extent of motor neuron migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904242", "l": "regulation of pancreatic trypsinogen secretion", "d": ["Any process that modulates the frequency, rate or extent of pancreatic trypsinogen secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0006858", "l": "extracellular transport", "d": ["The transport of substances that occurs outside cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060877", "l": "regionalization involved in semicircular canal formation", "d": ["The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.777964009505382", "identifiers": [{"i": "GO:0033238", "l": "regulation of amine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1905936", "l": "regulation of germ cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of germ cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0098543", "l": "detection of other organism", "d": ["The series of events in which a stimulus from another organism is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010729", "l": "positive regulation of hydrogen peroxide biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060696", "l": "regulation of phospholipid catabolic process", "d": ["Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0008611", "l": "ether lipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006231", "l": "dTMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0043650", "l": "dicarboxylic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.892466024748572", "identifiers": [{"i": "GO:0043094", "l": "cellular metabolic compound salvage", "d": ["Any process which produces a useful metabolic compound from derivatives of it without de novo synthesis, as carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0046037", "l": "GMP metabolic process", "d": ["The chemical reactions and pathways involving GMP, guanosine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901127", "l": "candicidin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of candicidin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000458", "l": "endonucleolytic cleavage between LSU-rRNA and 5S rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)", "d": ["Endonucleolytic cleavage to separate a pre-LSU-rRNA from a pre-5S rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140706", "l": "protein-containing complex localization to centriolar satellite", "d": ["A protein-containing complex localization by which the complex is transported to, or maintained in, the centriolar satellite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061763", "l": "multivesicular body-lysosome fusion", "d": ["The organelle membrane fusion process in which the membrane of a multivesicular body fuses with a lysosome to create a hybrid organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098038", "l": "non-replicative DNA transposition", "d": ["Process by which a transposable element is excised from the donor site and integrated at the target site without replication of the element. Also referred to as cut-and-paste transposition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043179", "l": "rhythmic excitation", "d": ["Any process involved in the generation of rhythmic, synchronous excitatory synaptic inputs in a neural circuit."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0018924", "l": "mandelate metabolic process", "d": ["The chemical reactions and pathways involving mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0042197", "l": "halogenated hydrocarbon metabolic process", "d": ["The chemical reactions and pathways involving halogenated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with halogen atoms. Halogens include fluorine, chlorine, bromine and iodine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120143", "l": "negative regulation of ecdysone receptor-mediated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0051455", "l": "monopolar spindle attachment to meiosis I kinetochore", "d": ["The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis I. During meiosis I sister kinetochores are lying next to each other facing the same spindle pole and monopolar attachment of the chromatid to the spindle occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006427", "l": "histidyl-tRNA aminoacylation", "d": ["The process of coupling histidine to histidyl-tRNA, catalyzed by histidyl-tRNA synthetase. The histidyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3''-OH group of a histidine-accetping tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021713", "l": "inferior olivary nucleus development", "d": ["The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046761", "l": "viral budding from plasma membrane", "d": ["A viral budding that starts with formation of a curvature in the host plasma membrane around which the virion particle assembles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901775", "l": "mitomycin C metabolic process", "d": ["The chemical reactions and pathways involving mitomycin C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150044", "l": "regulation of postsynaptic dense core vesicle exocytosis", "d": ["Any process that modulates the frequency, rate or extent of postsynaptic dense core vesicle exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0032611", "l": "interleukin-1 beta production", "d": ["The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000828", "l": "regulation of parathyroid hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of parathyroid hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:2000832", "l": "negative regulation of steroid hormone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010186", "l": "positive regulation of cellular defense response", "d": ["Any process that activates or increases the frequency, rate or extent of cellular defense response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014843", "l": "growth factor dependent regulation of skeletal muscle satellite cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903228", "l": "xanthosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of xanthosine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:1902749", "l": "regulation of cell cycle G2/M phase transition", "d": ["Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.432445482536949", "identifiers": [{"i": "GO:0008380", "l": "RNA splicing", "d": ["The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0050775", "l": "positive regulation of dendrite morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003233", "l": "bulbus arteriosus morphogenesis", "d": ["The process in which the bulbus arteriosus is generated and organized. The bulbus arteriosus is an elastic cardiac chamber."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901220", "l": "negative regulation of cardiac chamber morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034242", "l": "negative regulation of syncytium formation by plasma membrane fusion", "d": ["Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.450148715325263", "identifiers": [{"i": "GO:0007608", "l": "sensory perception of smell", "d": ["The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048774", "l": "cyanophore differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a cyanophore cell. Cyanophores are pigment cells derived from the neural crest. They contain a blue pigment of unknown chemical composition. The pigment is stored in fibrous organelles termed cyanosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000434", "l": "regulation of protein neddylation", "d": ["Any process that modulates the frequency, rate or extent of protein neddylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062227", "l": "positive regulation of adult somatic muscle development", "d": ["Any process that increases the rate, frequency or extent of adult somatic muscle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002940", "l": "tRNA N2-guanine methylation", "d": ["The process whereby a guanine in a tRNA is methylated at the N2 position of guanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905546", "l": "cellular response to phenylpropanoid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylpropanoid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051601", "l": "exocyst localization", "d": ["Any process in which an exocyst is transported to, or maintained in, a specific location. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905233", "l": "response to codeine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051612", "l": "negative regulation of serotonin uptake", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of serotonin into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0019319", "l": "hexose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009131", "l": "pyrimidine nucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904049", "l": "negative regulation of spontaneous neurotransmitter secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of spontaneous neurotransmitter secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903985", "l": "regulation of intestinal D-glucose absorption", "d": ["Any process that modulates the frequency, rate or extent of intestinal D-glucose absorption."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.622337805354121", "identifiers": [{"i": "GO:0001763", "l": "morphogenesis of a branching structure", "d": ["The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046498", "l": "S-adenosylhomocysteine metabolic process", "d": ["The chemical reactions and pathways involving S-adenosylhomocysteine; the L-enantiomer is formed from S-adenosylmethionine and is a strong inhibitor of S-adenosylmethionine-mediated methylation reactions. It can be cleaved to form adenosine and homocysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035210", "l": "prepupal development", "d": ["The process whose specific outcome is the progression of the prepupa over time, from its formation to the mature structure. The prepupal stage is a life stage interposed between the larval and the pupal stages in insects that undergo a complete metamorphosis. The start of the pre-pupal stage is marked by pupariation, and the end is marked by pupation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0010962", "l": "regulation of glucan biosynthetic process", "d": ["Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905344", "l": "prostaglandin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of prostaglandin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035364", "l": "thymine transport", "d": ["The directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903860", "l": "negative regulation of dendrite extension", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dendrite extension."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046645", "l": "positive regulation of gamma-delta T cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0034103", "l": "regulation of tissue remodeling", "d": ["Any process that modulates the frequency, rate, or extent of tissue remodeling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021784", "l": "postganglionic parasympathetic fiber development", "d": ["The process whose specific outcome is the progression of the postganglionic portion of the parasympathetic fiber over time, from its formation to the mature structure. The parasympathetic fiber is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900801", "l": "cspyrone B1 catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cspyrone B1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.349985564227573", "identifiers": [{"i": "GO:1901701", "l": "cellular response to oxygen-containing compound", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0003158", "l": "endothelium development", "d": ["The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060650", "l": "epithelial cell proliferation involved in mammary gland bud elongation", "d": ["The multiplication or reproduction of mammary gland bud epithelial cells, resulting in the elongation of the bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1904923", "l": "regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "d": ["Any process that modulates the frequency, rate or extent of autophagy of mitochondrion in response to mitochondrial depolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0045933", "l": "positive regulation of muscle contraction", "d": ["Any process that activates or increases the frequency, rate or extent of muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015885", "l": "5-formyltetrahydrofolate transport", "d": ["The directed movement of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, into, out of, within, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0030198", "l": "extracellular matrix organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905868", "l": "regulation of 3'-UTR-mediated mRNA stabilization", "d": ["Any process that modulates the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097323", "l": "B cell adhesion", "d": ["The attachment of a B cell to another cell via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0008655", "l": "pyrimidine-containing compound salvage", "d": ["Any process that generates a pyrimidine-containing compound, a nucleobase, nucleoside, nucleotide or nucleic acid that contains a pyrimidine base, from derivatives of them without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042424", "l": "catecholamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150013", "l": "negative regulation of neuron projection arborization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902230", "l": "negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0062223", "l": "regulation of somatic muscle development", "d": ["Any process that regulates the rate, frequency or extent of somatic muscle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030962", "l": "peptidyl-arginine dihydroxylation to peptidyl-3,4-dihydroxy-L-arginine", "d": ["The dihydroxylation of peptidyl-arginine to form peptidyl-3,4-dihydroxy-L-arginine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042986", "l": "positive regulation of amyloid precursor protein biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061961", "l": "positive regulation of heme oxygenase activity", "d": ["Any process that activates or increases the frequency or rate of heme oxygenase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0043618", "l": "regulation of transcription from RNA polymerase II promoter in response to stress", "d": ["Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042714", "l": "dosage compensation complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001916", "l": "positive regulation of T cell mediated cytotoxicity", "d": ["Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990168", "l": "protein K33-linked deubiquitination", "d": ["A protein deubiquitination process in which a K33-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is removed from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036300", "l": "B cell receptor internalization", "d": ["A receptor-mediated endocytosis process that results in the movement of a B cell receptor from the plasma membrane to the inside of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070837", "l": "dehydroascorbic acid transport", "d": ["The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901864", "l": "capsorubin metabolic process", "d": ["The chemical reactions and pathways involving capsorubin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0007306", "l": "egg chorion assembly", "d": ["Construction of the chorion portion of the egg, which is a protective, noncellular membrane that surrounds the eggs of various animals including insects and fish."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0070650", "l": "actin filament bundle distribution", "d": ["Any cellular process that establishes the spatial arrangement of actin filament bundles within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035702", "l": "monocyte homeostasis", "d": ["The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:1905818", "l": "regulation of chromosome separation", "d": ["Any process that modulates the frequency, rate or extent of chromosome separation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018134", "l": "peptide cross-linking via glycine oxazolecarboxylic acid", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046479", "l": "glycosphingolipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0062044", "l": "negative regulation of cardiac epithelial to mesenchymal transition", "d": ["Any process that stops or decreases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019300", "l": "rhamnose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of rhamnose, the hexose 6-deoxy-L-mannose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009597", "l": "detection of virus", "d": ["The series of events in which a stimulus from a virus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042467", "l": "orthokinesis", "d": ["The movement of a cell or organism in response to a stimulus in which the speed or frequency of movement is increased or decreased."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019480", "l": "L-alanine oxidation to pyruvate via D-alanine", "d": ["The chemical reactions and pathways resulting in the breakdown of L-alanine to pyruvate, with D-alanine as an intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1901626", "l": "regulation of postsynaptic membrane organization", "d": ["Any process that modulates the frequency, rate or extent of postsynaptic membrane organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051217", "l": "molybdenum incorporation via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide)", "d": ["The incorporation of molybdenum into a protein via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044828", "l": "negative regulation by host of viral genome replication", "d": ["A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral genome replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042188", "l": "1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1901724", "l": "positive regulation of cell proliferation involved in kidney development", "d": ["Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060066", "l": "oviduct development", "d": ["The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006079", "l": "(1->6)-beta-D-glucan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (1->6)-beta-D-glucans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000132", "l": "negative regulation of tyramine signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of tyramine signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905424", "l": "regulation of Wnt-mediated midbrain dopaminergic neuron differentiation", "d": ["Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044575", "l": "cellulosome assembly", "d": ["The assembly of a cellulosome, a macromolecular multi-enzyme complex in bacteria that facilitates the breakdown of cellulase, hemicellulase and pectin in the plant cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0042747", "l": "circadian sleep/wake cycle, REM sleep", "d": ["A stage in the circadian sleep cycle during which dreams occur and the body undergoes marked changes including rapid eye movement, loss of reflexes, and increased pulse rate and brain activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018281", "l": "GSI anchor biosynthetic process via N-seryl-glycosylsphingolipidinositolethanolamine", "d": ["The formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0000495", "l": "box H/ACA RNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a box H/ACA RNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.444551060876734", "identifiers": [{"i": "GO:0030324", "l": "lung development", "d": ["The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900654", "l": "positive regulation of demethylkotanin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of demethylkotanin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0044416", "l": "induction by symbiont of host defense response", "d": ["The activation by an organism of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060556", "l": "regulation of vitamin D biosynthetic process", "d": ["Any process that modulates the rate frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042082", "l": "GSI anchor biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a glycosylsphingolipidinositol (GSI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The sphingolipid group is linked, via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via a ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GSI anchors have variants on this canonical linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0051055", "l": "negative regulation of lipid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0043582", "l": "sporangium development", "d": ["The process whose specific outcome is the progression of the sporangium over time, from its formation to the mature structure. A sporangium is a structure producing and containing spores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017195", "l": "N-terminal peptidyl-lysine N2-acetylation", "d": ["The acetylation of the N-terminal lysine of proteins to form the derivative N2-acetyl-L-lysine. The occurrence of this modification has not been confirmed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:0000917", "l": "division septum assembly", "d": ["The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902623", "l": "negative regulation of neutrophil migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0071063", "l": "sensory perception of wind", "d": ["The series of events required for an organism to receive sensory mechanical stimulus resulting from air flow, convert it to a molecular signal, and recognize and characterize the signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018026", "l": "peptidyl-lysine monomethylation", "d": ["The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010067", "l": "procambium histogenesis", "d": ["The formation of the primary meristem or meristematic tissue that gives rise to the primary vascular tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900655", "l": "regulation of diorcinol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of diorcinol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097694", "l": "establishment of RNA localization to telomere", "d": ["The directed movement of RNA to a specific location in the telomeric region of a chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110079", "l": "regulation of placenta blood vessel development", "d": ["Any process that modulates the frequency, rate or extent of placenta blood vessel development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046141", "l": "corrin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990781", "l": "response to immobilization stress combined with electrical stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus given while being held immobile."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018006", "l": "N-terminal protein amino acid glucuronylation", "d": ["The glucuronylation of the N-terminal amino acid of proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061588", "l": "calcium activated phospholipid scrambling", "d": ["The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034153", "l": "positive regulation of toll-like receptor 6 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 6 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.349257862016486", "identifiers": [{"i": "GO:0080134", "l": "regulation of response to stress", "d": ["Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002284", "l": "myeloid dendritic cell differentiation involved in immune response", "d": ["The process in which an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010415", "l": "unsubstituted mannan metabolic process", "d": ["The chemical reactions and pathways involving the mannan backbone, the unsubstituted polymer of D-mannose units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002880", "l": "regulation of chronic inflammatory response to non-antigenic stimulus", "d": ["Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090300", "l": "positive regulation of neural crest formation", "d": ["Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051039", "l": "positive regulation of transcription involved in meiotic cell cycle", "d": ["Any process that activates or increases the frequency, rate or extent of transcription as part of a meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000731", "l": "negative regulation of termination of RNA polymerase I transcription", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase I transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000693", "l": "positive regulation of seed maturation", "d": ["Any process that activates or increases the frequency, rate or extent of seed maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036073", "l": "perichondral ossification", "d": ["Intramembranous ossification from the surface of a cartilage element as the perichondrium becomes a periosteum, without replacement of cartilage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141043", "l": "evasion of host innate immune recognition", "d": ["A process by which a symbiont avoids recognition by host's innate immune response by altering a conserved molecule recognized by the host's cell surface and intracellular innate immune receptors, including Toll-like receptors, and NOD-like receptors. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021840", "l": "directional guidance of interneurons involved in migration from the subpallium to the cortex", "d": ["The creation and reception of signals that control the direction of migration of interneurons as a component of the process of migration from the subpallium to the cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0032073", "l": "negative regulation of restriction endodeoxyribonuclease activity", "d": ["Any process that stops or reduces the rate of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902628", "l": "positive regulation of assembly of large subunit precursor of preribosome", "d": ["Any process that activates or increases the frequency, rate or extent of assembly of a large subunit precursor of preribosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090238", "l": "positive regulation of arachidonic acid secretion", "d": ["Any process that increases the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097321", "l": "cell growth mode switching, filamentous to budding", "d": ["The process in which a cell switches from growing as a filament (elongated cells attached end-to-end) to growing as a round budding cell. An example of this is observed in Candida albicans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010973", "l": "positive regulation of division septum assembly", "d": ["Any process that increases the frequency, rate or extent of division septum formation. division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900482", "l": "positive regulation of diacylglycerol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of diacylglycerol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060156", "l": "milk ejection reflex", "d": ["A reflex that occurs in response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. Signaling never reaches a level of consciousness."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061269", "l": "mesonephric glomerular mesangial cell proliferation involved in mesonephros development", "d": ["The multiplication or reproduction of glomerular mesangial cells in the mesonephros, resulting in the expansion of the population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900085", "l": "negative regulation of peptidyl-tyrosine autophosphorylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-tyrosine autophosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002476", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class Ib", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046494", "l": "rhizobactin 1021 metabolic process", "d": ["The chemical reactions and pathways involving rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902013", "l": "poly(glycerol phosphate) teichoic acid metabolic process", "d": ["The chemical reactions and pathways involving poly(glycerol phosphate) teichoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000081", "l": "positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019228", "l": "neuronal action potential", "d": ["An action potential that occurs in a neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071286", "l": "cellular response to magnesium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902762", "l": "regulation of embryonic skeletal joint development", "d": ["Any process that modulates the frequency, rate or extent of embryonic skeletal joint development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090208", "l": "positive regulation of triglyceride metabolic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046478", "l": "lactosylceramide metabolic process", "d": ["The chemical reactions and pathways involving lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120317", "l": "sperm mitochondrial sheath assembly", "d": ["The assembly and organization of the sperm mitochondrial sheath, the tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904529", "l": "regulation of actin filament binding", "d": ["Any process that modulates the frequency, rate or extent of actin filament binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019349", "l": "ribitol metabolic process", "d": ["The chemical reactions and pathways involving ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. It occurs free in some plants and is a component of riboflavin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0030449", "l": "regulation of complement activation", "d": ["Any process that modulates the frequency, rate or extent of complement activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900310", "l": "negative regulation of maltoheptaose metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0006787", "l": "porphyrin-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0006023", "l": "aminoglycan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0060839", "l": "endothelial cell fate commitment", "d": ["The commitment of a cell to an endothelial cell fate and its capacity to differentiate into an endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070132", "l": "regulation of mitochondrial translational initiation", "d": ["Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902543", "l": "negative regulation of protein localization to mitotic spindle pole body", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitotic spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0033014", "l": "tetrapyrrole biosynthetic process", "d": ["The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905407", "l": "regulation of creatine transmembrane transporter activity", "d": ["Any process that modulates the frequency, rate or extent of creatine transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070158", "l": "mitochondrial seryl-tRNA aminoacylation", "d": ["The process of coupling serine to seryl-tRNA in a mitochondrion, catalyzed by seryl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.531911357225393", "identifiers": [{"i": "GO:0006807", "l": "nitrogen compound metabolic process", "d": ["The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903457", "l": "lactate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lactate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905951", "l": "mitochondrion DNA recombination", "d": ["Any DNA recombination that takes place in mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0043403", "l": "skeletal muscle tissue regeneration", "d": ["The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900577", "l": "gerfelin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of gerfelin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032254", "l": "establishment of secretory granule localization", "d": ["The directed movement of a secretory granule to a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0016339", "l": "calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "d": ["The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009920", "l": "cell plate formation involved in plant-type cell wall biogenesis", "d": ["The cell cycle process in which the cell plate is formed at the equator of the spindle in the dividing cells during early telophase. An example of this is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051972", "l": "regulation of telomerase activity", "d": ["Any process that modulates the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Telomerases catalyze extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902078", "l": "positive regulation of lateral motor column neuron migration", "d": ["Any process that activates or increases the frequency, rate or extent of lateral motor column neuron migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150078", "l": "positive regulation of neuroinflammatory response", "d": ["Any process that activates or increases the frequency, rate or extent of neuroinflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021996", "l": "lamina terminalis formation", "d": ["The process in which the anterior-most portion of the neural axis is formed by closure of the anterior neuropore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0060788", "l": "ectodermal placode formation", "d": ["The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060789", "l": "hair follicle placode formation", "d": ["The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0086022", "l": "SA node cell-atrial cardiac muscle cell adhesion involved in cell communication", "d": ["The attachment of SA node cardiomyocyte to an atrial cardiomyocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901587", "l": "positive regulation of acid-sensing ion channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of acid-sensing ion channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0051017", "l": "actin filament bundle assembly", "d": ["The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097699", "l": "vascular endothelial cell response to fluid shear stress", "d": ["Any response to fluid shear stress in a vascular endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048669", "l": "collateral sprouting in absence of injury", "d": ["The process in which outgrowths develop from the axons of intact undamaged neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900881", "l": "18-methylnonadec-1-ene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 18-methylnonadec-1-ene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034473", "l": "U1 snRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a U1 snRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097622", "l": "cytoplasmic translational elongation through polyproline stretches", "d": ["The successive addition of amino acid residues to a nascent polypeptide chain, proceeding through regions of multiple repeated proline codons, during protein biosynthesis in the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.155424086811493", "identifiers": [{"i": "GO:0002695", "l": "negative regulation of leukocyte activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902606", "l": "regulation of large conductance calcium-activated potassium channel activity", "d": ["Any process that modulates the frequency, rate or extent of large conductance calcium-activated potassium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902943", "l": "positive regulation of voltage-gated chloride channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of voltage-gated chloride channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905615", "l": "positive regulation of developmental vegetative growth", "d": ["Any process that activates or increases the frequency, rate or extent of developmental vegetative growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006124", "l": "ferredoxin metabolic process", "d": ["The chemical reactions and pathways involving ferredoxin, any simple, nonenzymatic iron-sulfur protein that is characterized by having equal numbers of atoms of iron and labile sulfur. Iron and sulfur atoms are present in one or two clusters of two or four atoms of each."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:1903036", "l": "positive regulation of response to wounding", "d": ["Any process that activates or increases the frequency, rate or extent of response to wounding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039563", "l": "disruption by virus of host JAK-STAT cascade via inhibition of STAT1 activity", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT1 (signal transducer and activator of transcription 1)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003003", "l": "follicular fluid formation in ovarian follicle antrum involved in fused antrum stage", "d": ["The ovulation cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the fused antrum stage of oogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051203", "l": "peptidyl-aspartic acid reduction to form L-aspartyl aldehyde", "d": ["The reduction of peptidyl-aspartic acid to form peptidyl-L-aspartyl aldehyde, as found photosystem II P680 chlorophyll A apoprotein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902031", "l": "regulation of NADP metabolic process", "d": ["Any process that modulates the frequency, rate or extent of NADP metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007313", "l": "maternal specification of dorsal/ventral axis, oocyte, soma encoded", "d": ["Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by somatic cells. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044751", "l": "cellular response to human chorionic gonadotropin stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0141027", "l": "perturbation by symbiont of host actin cytoskeleton", "d": ["The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045943", "l": "positive regulation of transcription by RNA polymerase I", "d": ["Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036118", "l": "hyaluranon cable assembly", "d": ["A process that results in the aggregation, arrangement and bonding together of a hyaluranon cable, a cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060392", "l": "negative regulation of SMAD protein signal transduction", "d": ["Any process that decreases the rate, frequency or extent of the SMAD protein signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0006568", "l": "tryptophan metabolic process", "d": ["The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900503", "l": "regulation of cellulosome assembly", "d": ["Any process that modulates the frequency, rate or extent of cellulosome assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021916", "l": "inductive cell-cell signaling between paraxial mesoderm and motor neuron precursors", "d": ["Short range signaling between cells of the paraxial mesoderm and motor neuron precursors in the spinal cord that specifies the fate of the motor column neuron precursors along the anterior-posterior axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0000212", "l": "meiotic spindle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033390", "l": "putrescine biosynthetic process from arginine via N-carbamoylputrescine", "d": ["The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine, via the intermediate N-carbamoylputrescine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in two single enzymatic steps."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0062025", "l": "regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "d": ["Any process that modualtes the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033228", "l": "cysteine export across plasma membrane", "d": ["The directed movement of cysteine from inside of a cell, across the plasma membrane and into the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000358", "l": "positive regulation of kidney smooth muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of kidney smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0044868", "l": "modulation by host of viral molecular function", "d": ["A process in which a host organism modulates the frequency, rate or extent of any molecular function being mediated by a virus with which it is infected."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120292", "l": "positive regulation of mitotic recombination-dependent replication fork processing", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic recombination-dependent replication fork processing. Regulation of mitotic recombination prevents recombination between inappropriate homologous sequences. Proteins involved in homologous recombination are required for replication restart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001152", "l": "negative regulation of renal water transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of renal water transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018253", "l": "peptide cross-linking via 5-imidazolinone glycine", "d": ["The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue n, an alanine, serine or cysteine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with an oxidation of residue n+1 to form an active aldehyde."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900914", "l": "regulation of octadecene biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of octadecene biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032660", "l": "regulation of interleukin-17 production", "d": ["Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900324", "l": "regulation of maltotriulose transport", "d": ["Any process that modulates the frequency, rate or extent of maltotriulose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018060", "l": "N-terminal peptidyl-cysteine deamination", "d": ["The oxidative deamination of N-terminal peptidyl-cysteine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080178", "l": "5-carbamoylmethyl uridine residue modification", "d": ["The chemical reactions and pathways involving the addition of a 5-carbamoylmethyl group to a uridine residue in RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.154928939654667", "identifiers": [{"i": "GO:0061527", "l": "dopamine secretion, neurotransmission", "d": ["The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0015757", "l": "galactose transmembrane transport", "d": ["The process in which galactose is transported across a lipid bilayer, from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007403", "l": "glial cell fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into a glial cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904542", "l": "regulation of free ubiquitin chain polymerization", "d": ["Any process that modulates the frequency, rate or extent of free ubiquitin chain polymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0010634", "l": "positive regulation of epithelial cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of epithelial cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0120211", "l": "proacrosomal vesicle fusion", "d": ["Fusion of the membrane of proacrosomal vesicle with the membrane of another proacrosomal vesicle to form the acrosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0021578", "l": "hindbrain maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:2000235", "l": "regulation of tRNA processing", "d": ["Any process that modulates the frequency, rate or extent of tRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007506", "l": "gonadal mesoderm development", "d": ["The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.773387538292397", "identifiers": [{"i": "GO:0060249", "l": "anatomical structure homeostasis", "d": ["A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046414", "l": "organomercury biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of organomercury compounds, any organic compound containing a mercury atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048809", "l": "analia morphogenesis", "d": ["The process in which the anatomical structures of analia are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia morphogenesis in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043979", "l": "histone H2B-K5 acetylation", "d": ["The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 5 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060410", "l": "negative regulation of acetylcholine metabolic process", "d": ["Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0052541", "l": "plant-type cell wall cellulose metabolic process", "d": ["The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014022", "l": "neural plate elongation", "d": ["The process in which the neural plate is shaped by the intrinsic movement of the epidermal and neural plate regions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042864", "l": "pyochelin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905530", "l": "negative regulation of uracil import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of uracil import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0042335", "l": "cuticle development", "d": ["The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031036", "l": "myosin II filament assembly", "d": ["The formation of a bipolar filament composed of myosin II molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0009956", "l": "radial pattern formation", "d": ["The regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903371", "l": "regulation of endoplasmic reticulum tubular network organization", "d": ["Any process that modulates the frequency, rate or extent of endoplasmic reticulum tubular network organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.767641576330163", "identifiers": [{"i": "GO:0048514", "l": "blood vessel morphogenesis", "d": ["The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019304", "l": "anaerobic rhamnose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose, that occurs in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000478", "l": "positive regulation of metanephric podocyte development", "d": ["Any process that activates or increases the frequency, rate or extent of metanephric glomerular visceral epithelial cell development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905282", "l": "regulation of epidermal growth factor receptor signaling pathway involved in heart process", "d": ["Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0036066", "l": "protein O-linked fucosylation", "d": ["The process of transferring a fucosyl group to a serine or threonine residues in a protein acceptor molecule, to form an O-linked protein-sugar linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904442", "l": "negative regulation of thyroid gland epithelial cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of thyroid gland epithelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0010810", "l": "regulation of cell-substrate adhesion", "d": ["Any process that modulates the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:2000316", "l": "regulation of T-helper 17 type immune response", "d": ["Any process that modulates the frequency, rate or extent of T-helper 17 type immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045670", "l": "regulation of osteoclast differentiation", "d": ["Any process that modulates the frequency, rate or extent of osteoclast differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046866", "l": "tetraterpenoid transport", "d": ["The directed movement of tetraterpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tetraterpenoids are terpenoids with eight isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033572", "l": "transferrin transport", "d": ["The directed movement of transferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0009161", "l": "ribonucleoside monophosphate metabolic process", "d": ["The chemical reactions and pathways involving a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007490", "l": "tergite morphogenesis", "d": ["The process in which the anatomical structures of the tergite are generated and organized. The tergite is the primary plate or sclerite forming the dorsal surface of any insect body segment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046321", "l": "positive regulation of fatty acid oxidation", "d": ["Any process that activates or increases the frequency, rate or extent of fatty acid oxidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045501", "l": "regulation of sevenless signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the sevenless signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009150", "l": "purine ribonucleotide metabolic process", "d": ["The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0002863", "l": "positive regulation of inflammatory response to antigenic stimulus", "d": ["Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010040", "l": "response to iron(II) ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035907", "l": "dorsal aorta development", "d": ["The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009439", "l": "cyanate metabolic process", "d": ["The chemical reactions and pathways involving cyanate, NCO-, the anion of cyanic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032243", "l": "negative regulation of nucleoside transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.050408934017838", "identifiers": [{"i": "GO:0030705", "l": "cytoskeleton-dependent intracellular transport", "d": ["The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.738263026760649", "identifiers": [{"i": "GO:0051098", "l": "regulation of binding", "d": ["Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902907", "l": "proteasome storage granule disassembly", "d": ["The disaggregation of a proteasome storage granule into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075293", "l": "response to host pH environment", "d": ["Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the pH conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032817", "l": "regulation of natural killer cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of natural killer cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015779", "l": "glucuronoside transport", "d": ["The directed movement of glucuronosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052544", "l": "defense response by callose deposition in cell wall", "d": ["Any process in which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032678", "l": "regulation of interleukin-9 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-9 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090707", "l": "establishment of plant organ orientation", "d": ["The process that determines the orientation of a plant organ or tissue with reference to an axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901288", "l": "iron-sulfur-molybdenum cofactor biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022015", "l": "radial glial cell division in pallium", "d": ["The division of a radial glial cell in the pallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099018", "l": "evasion by virus of host restriction-modification system", "d": ["Any process, either active or passive, by which a virus evades the DNA restriction modification system of its host. Some viruses encode their own methyltransferase in order to protect their genome from host restriction enzymes. Others directly inhibit restruction enzymes while some use unusual bases in their genome to avoid restriction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045792", "l": "negative regulation of cell size", "d": ["Any process that reduces cell size."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014895", "l": "smooth muscle hypertrophy", "d": ["The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072429", "l": "response to intra-S DNA damage checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of intra-S DNA damage checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1990440", "l": "positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress", "d": ["Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0090278", "l": "negative regulation of peptide hormone secretion", "d": ["Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032346", "l": "positive regulation of aldosterone metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036515", "l": "serotonergic neuron axon guidance", "d": ["The chemotaxis process that directs the migration of an axon growth cone of a serotonergic neuron to a specific target site in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034175", "l": "regulation of toll-like receptor 12 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 12 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060843", "l": "venous endothelial cell differentiation", "d": ["The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000630", "l": "positive regulation of miRNA metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of miRNA metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0007289", "l": "spermatid nucleus differentiation", "d": ["The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0140820", "l": "cytosol to Golgi apparatus transport", "d": ["The directed movement of substances from the cytosol into the Golgi apparatus of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106040", "l": "regulation of GABA-A receptor activity", "d": ["Any process that modulates the frequency, rate or extent of GABA-A receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "36.946255620710332", "identifiers": [{"i": "GO:0048729", "l": "tissue morphogenesis", "d": ["The process in which the anatomical structures of a tissue are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.393132858203678", "identifiers": [{"i": "GO:0006468", "l": "protein phosphorylation", "d": ["The process of introducing a phosphate group on to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048148", "l": "behavioral response to cocaine", "d": ["Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010390", "l": "histone monoubiquitination", "d": ["The modification of histones by addition of a single ubiquitin group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051501", "l": "diterpene phytoalexin metabolic process", "d": ["The chemical reactions and pathways involving diterpene phytoalexins, a class of diterpene formed in plants in response to fungal infection, physical damage, chemical injury, or a pathogenic process; they are sometimes referred to as plant antibiotics. Diterpenes are unsaturated hydrocarbons containing 20 carbon atoms and 4 branched methyl groups and are made up of isoprenoid units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905008", "l": "regulation of L-lysine import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of L-lysine import into cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006948", "l": "induction by virus of host cell-cell fusion", "d": ["The process of syncytia-forming cell-cell fusion, caused by a virus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046655", "l": "folic acid metabolic process", "d": ["The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000645", "l": "negative regulation of receptor catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of receptor catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010916", "l": "negative regulation of very-low-density lipoprotein particle clearance", "d": ["Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075265", "l": "positive regulation of oogonium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0090069", "l": "regulation of ribosome biogenesis", "d": ["Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003111", "l": "positive regulation of heart rate by circulating epinephrine", "d": ["The process in which the secretion of epinephrine into the bloodstream increases the rate of heart muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900231", "l": "regulation of single-species biofilm formation on inanimate substrate", "d": ["Any process that modulates the frequency, rate or extent of single-species biofilm formation on inanimate substrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006620", "l": "post-translational protein targeting to endoplasmic reticulum membrane", "d": ["The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0002097", "l": "tRNA wobble base modification", "d": ["The process in which the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally modified."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000558", "l": "positive regulation of immunoglobulin production in mucosal tissue", "d": ["Any process that activates or increases the frequency, rate or extent of immunoglobulin production in mucosal tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061104", "l": "adrenal chromaffin cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0060258", "l": "negative regulation of filamentous growth", "d": ["Any process that decreases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140731", "l": "regulation of amphiregulin production", "d": ["Any process that modulates the frequency, rate, or extent of production of amphiregulin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990892", "l": "mitotic chromosome arm condensation", "d": ["The cell cycle process in which chromosome arm chromatin structure is compacted prior to and during mitosis in eukaryotic cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010838", "l": "positive regulation of keratinocyte proliferation", "d": ["Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036460", "l": "cellular response to cell envelope stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stress acting at the cell envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006240", "l": "dCDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dCDP, deoxycytidine 5'-diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0046185", "l": "aldehyde catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901812", "l": "beta-carotene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-carotene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990751", "l": "Schwann cell chemotaxis", "d": ["The directed movement of a Schwann cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901559", "l": "response to ribavirin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ribavirin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039723", "l": "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity", "d": ["Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of a host serine/threonine kinase TBK1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0141005", "l": "retrotransposon silencing by heterochromatin formation", "d": ["A retrotransposon silencing mechanism involving heterochromatin assembly. Heterochromatin is a chromatin conformation that is refractory to transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903054", "l": "negative regulation of extracellular matrix organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046841", "l": "trisporic acid metabolic process", "d": ["The chemical reactions and pathways involving trisporic acid, a carotenoic acid derivative used as a pheromone in some species of Zygomycota."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071712", "l": "ER-associated misfolded protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of misfolded proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901847", "l": "nicotinate metabolic process", "d": ["The chemical reactions and pathways involving nicotinate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903741", "l": "negative regulation of phosphatidate phosphatase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidate phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0032493", "l": "response to bacterial lipoprotein", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007302", "l": "nurse cell nucleus anchoring", "d": ["Attachment of the nurse cell nucleus to the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070792", "l": "Hulle cell development", "d": ["The process whose specific outcome is the progression of Hulle cells over time, from their formation to the mature structures. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.790184063220053", "identifiers": [{"i": "GO:0072521", "l": "purine-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990514", "l": "5' transitive RNA interference", "d": ["An RNA interference where the silencing signal spreads 5' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0035936", "l": "testosterone secretion", "d": ["The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0090735", "l": "DNA repair complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a DNA repair complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0006564", "l": "L-serine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072540", "l": "T-helper 17 cell lineage commitment", "d": ["The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0061209", "l": "cell proliferation involved in mesonephros development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072748", "l": "cellular response to tacrolimus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus (FK506) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.085121200529862", "identifiers": [{"i": "GO:0010243", "l": "response to organonitrogen compound", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007493", "l": "endodermal cell fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into an endoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0045048", "l": "protein insertion into ER membrane", "d": ["The process that results in incorporation of a protein into an endoplasmic reticulum (ER) membrane. It depends on specific topogenic sequences of amino acids that ensure that a protein acquires the proper orientation during its insertion into the ER membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050739", "l": "peptide cross-linking via S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium", "d": ["The cross-linking of a tyrosine residue to a tryptophan residue and a methionine residue to form S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070966", "l": "nuclear-transcribed mRNA catabolic process, no-go decay", "d": ["The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900888", "l": "negative regulation of pentadecane biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.303669562290317", "identifiers": [{"i": "GO:0007276", "l": "gamete generation", "d": ["The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018305", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901105", "l": "tetracenomycin C catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tetracenomycin C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.744066580938323", "identifiers": [{"i": "GO:0061333", "l": "renal tubule morphogenesis", "d": ["The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045691", "l": "regulation of embryo sac central cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of female gametophyte central cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904212", "l": "regulation of iodide transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of iodide transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0071383", "l": "cellular response to steroid hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0003416", "l": "endochondral bone growth", "d": ["The increase in size or mass of an endochondral bone that contributes to the shaping of the bone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000534", "l": "positive regulation of renal albumin absorption", "d": ["Any process that activates or increases the frequency, rate or extent of renal albumin absorption."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:2000125", "l": "regulation of octopamine or tyramine signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of octopamine or tyramine signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902626", "l": "assembly of large subunit precursor of preribosome", "d": ["The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015702", "l": "chlorate transport", "d": ["The directed movement of chlorate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0052093", "l": "formation of specialized structure for nutrient acquisition", "d": ["The assembly of a symbiotic cellular or anatomical structure for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061335", "l": "cell growth involved in Malpighian tubule morphogenesis", "d": ["The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019578", "l": "aldaric acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0044511", "l": "envenomation resulting in modulation of receptor activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of receptor activity in of the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.651613913496419", "identifiers": [{"i": "GO:0042182", "l": "ketone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006843", "l": "mitochondrial citrate transmembrane transport", "d": ["The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into or out of a mitochondrial matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075514", "l": "endosome lysis involved in viral entry into host cell", "d": ["Viral-induced lysis of the endosome involved in uptake of a virus into a host cell. Occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents from the endosome into the host cell cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090549", "l": "response to carbon starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of a carbon source."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033475", "l": "indoleacetic acid amide conjugate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an amino acid or polypeptide through an amide bond."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0007538", "l": "primary sex determination", "d": ["The sex determination process that results in the initial specification of sexual status of an individual organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007395", "l": "dorsal closure, spreading of leading edge cells", "d": ["Dorsally-directed movement of a cell at the leading edge of the epithelium over the amnioserosa."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052154", "l": "modulation by symbiont of host B-cell mediated immune response", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062234", "l": "platelet activating factor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of platelet activating factor, 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019800", "l": "peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan", "d": ["The formation of a cross-link between peptide chains mediated by a chondroitin 4-sulfate glycosaminoglycan that originates from a typical O-glycosidic link to serine of one chain; the other chain is esterified, via the alpha-carbon of its C-terminal Asp, to C-6 of an internal N-acetylgalactosamine of the glycosaminoglycan chain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902123", "l": "(-)-pinoresinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (-)-pinoresinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:1901342", "l": "regulation of vasculature development", "d": ["Any process that modulates the frequency, rate or extent of vasculature development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0120186", "l": "negative regulation of protein localization to chromatin", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034371", "l": "chylomicron remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072167", "l": "specification of mesonephric tubule identity", "d": ["The process in which the tubules of the mesonephros acquire their identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046720", "l": "citric acid secretion", "d": ["The controlled release of citric acid, 2-hydroxy-1,2,3-propanetricarboxylic acid, by a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900736", "l": "regulation of phospholipase C-activating G protein-coupled receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141032", "l": "perturbation by symbiont of host actin cytoskeleton via actin filament reorganization", "d": ["The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by reorganizing the actin filaments, in a way that keeps the total filementous actin remains approximately constant. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150071", "l": "negative regulation of arginase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of arginase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033686", "l": "positive regulation of luteinizing hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099138", "l": "altruistic, chimeric sorocarp development", "d": ["Development of a chimeric sorocarp in which cells of all genotypes have an equal chance of becoming a spore cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0016036", "l": "cellular response to phosphate starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097096", "l": "facial suture morphogenesis", "d": ["The process in which any suture between facial bones is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071434", "l": "cell chemotaxis to angiotensin", "d": ["The directed movement of a motile cell in response to the presence of angiotensin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901192", "l": "positive regulation of formation of translation initiation ternary complex", "d": ["Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031394", "l": "positive regulation of prostaglandin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0000755", "l": "cytogamy", "d": ["During conjugation with cellular fusion, the process resulting in creating a single cell from complementary mating types. The localized remodeling and dissolution of external protective structures allow the fusion of the plasma membranes and cytoplasmic mixing. An example of this process is found in Saccharomyces cerevisiae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902617", "l": "response to fluoride", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903081", "l": "negative regulation of C-C chemokine receptor CCR7 signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0072710", "l": "response to hydroxyurea", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001046", "l": "positive regulation of integrin-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010129", "l": "anaerobic cyclohexane-1-carboxylate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cyclohexane-1-carboxylate, a alicyclic acid, in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110084", "l": "negative regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060402", "l": "calcium ion transport into cytosol", "d": ["The directed movement of calcium ions (Ca2+) into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:0050657", "l": "nucleic acid transport", "d": ["The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0006779", "l": "porphyrin-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035785", "l": "intracellular nickel ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of nickel ions within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021659", "l": "rhombomere 3 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 3. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000302", "l": "positive regulation of synaptic vesicle exocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901290", "l": "succinyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of succinyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0002532", "l": "production of molecular mediator involved in inflammatory response", "d": ["The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031951", "l": "positive regulation of glucocorticoid catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902137", "l": "(-)-secoisolariciresinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (-)-secoisolariciresinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060311", "l": "negative regulation of elastin catabolic process", "d": ["Any process that decreases the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140639", "l": "positive regulation of pyroptosis", "d": ["Any process that increases the frequency, rate or extent of pyroptosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904241", "l": "positive regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900065", "l": "regulation of ethanol catabolic process", "d": ["Any process that modulates the frequency, rate or extent of ethanol catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0044820", "l": "mitotic telomere tethering at nuclear periphery", "d": ["The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071104", "l": "response to interleukin-9", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0060669", "l": "embryonic placenta morphogenesis", "d": ["The process in which the embryonic placenta is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1905413", "l": "regulation of dense core granule exocytosis", "d": ["Any process that modulates the frequency, rate or extent of dense core granule exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090127", "l": "positive regulation of synapse maturation by synaptic transmission", "d": ["Any process that increases the extent of synaptic maturation as a result of the communication from a pre-synaptic cell to a post-synaptic cell across a synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006533", "l": "aspartate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043536", "l": "positive regulation of blood vessel endothelial cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120006", "l": "regulation of glutamatergic neuron differentiation", "d": ["Any process that modulates the frequency, rate or extent of glutamatergic neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046105", "l": "thymidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000799", "l": "positive regulation of amniotic stem cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of amniotic stem cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "17.679441825983844", "identifiers": [{"i": "GO:0044271", "l": "cellular nitrogen compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009258", "l": "10-formyltetrahydrofolate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021831", "l": "embryonic olfactory bulb interneuron precursor migration", "d": ["The directed movement of individual interneuron precursors during the embryonic development of the olfactory bulb."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061376", "l": "mammillotegmental axonal tract development", "d": ["The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035066", "l": "positive regulation of histone acetylation", "d": ["Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to a histone protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0061241", "l": "mesonephric nephron epithelium development", "d": ["The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019414", "l": "aerobic respiration, using sulfur or sulfate as electron donor", "d": ["An aerobic respiration process in which a sulfur-containing molecule (hydrogen sulfide, sulfur, sulfite, thiosulfate, and various polythionates) is oxidized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052163", "l": "symbiont defense to host-produced nitric oxide", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of the production of nitric oxide as part of the innate immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090012", "l": "negative regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway that contributes to the formation of the primitive streak."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021993", "l": "initiation of neural tube closure", "d": ["The process in which closure points are established at multiple points and along the neural rostrocaudal axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071766", "l": "Actinobacterium-type cell wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901908", "l": "diadenosine hexaphosphate metabolic process", "d": ["The chemical reactions and pathways involving diadenosine hexaphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046492", "l": "heme B metabolic process", "d": ["The chemical reactions and pathways involving heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045065", "l": "cytotoxic T cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0035966", "l": "response to topologically incorrect protein", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0009687", "l": "abscisic acid metabolic process", "d": ["The chemical reactions and pathways involving abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032209", "l": "positive regulation of telomere maintenance via recombination", "d": ["Any process that activates or increases the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0046110", "l": "xanthine metabolic process", "d": ["The chemical reactions and pathways involving xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903974", "l": "positive regulation of cellular response to macrophage colony-stimulating factor stimulus", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006188", "l": "IMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019310", "l": "inositol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035216", "l": "haltere disc development", "d": ["Progression of the haltere imaginal disc over time, from its initial formation through to its metamorphosis to form the adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160071", "l": "prevention of polyspermy during double fertilization", "d": ["The regulation of double fertilization forming a zygote and endosperm process that ensures that only a single sperm cell fertilizes one egg cell and another single sperm cell fertilizes one central cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097397", "l": "cellular response to interleukin-32", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0031334", "l": "positive regulation of protein-containing complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of protein complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0014900", "l": "muscle hyperplasia", "d": ["A muscle system process that results in an increase in cell number by cell division, often leading to an increase in the size of an organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048808", "l": "male genitalia morphogenesis", "d": ["The process in which the anatomical structures of male genitalia are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014746", "l": "regulation of tonic skeletal muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of tonic skeletal muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044854", "l": "plasma membrane raft assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a plasma membrane raft."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0019660", "l": "glycolytic fermentation", "d": ["Fermentation that includes the anaerobic conversion of glucose to pyruvate via the glycolytic pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0021799", "l": "cerebral cortex radially oriented cell migration", "d": ["The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.56681308101922", "identifiers": [{"i": "GO:0032102", "l": "negative regulation of response to external stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0001797", "l": "negative regulation of type IIa hypersensitivity", "d": ["Any process that stops, prevents, or reduces the rate of type IIa hypersensitivity, a type of inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0051646", "l": "mitochondrion localization", "d": ["Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045341", "l": "MHC class I biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of major histocompatibility protein class I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.356779217613806", "identifiers": [{"i": "GO:0045785", "l": "positive regulation of cell adhesion", "d": ["Any process that activates or increases the frequency, rate or extent of cell adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003238", "l": "conus arteriosus development", "d": ["The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032803", "l": "regulation of low-density lipoprotein particle receptor catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048392", "l": "intermediate mesodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an intermediate mesoderm cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002481", "l": "antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048150", "l": "behavioral response to ether", "d": ["Any process that results in a change in the behavior of an organism as a result of an ether stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0044091", "l": "membrane biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110038", "l": "negative regulation of nematode male tail tip morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of nematode male tail tip morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0098511", "l": "sensory perception of low humidity", "d": ["The series of events required for an organism to detect low environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036086", "l": "positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045678", "l": "positive regulation of R7 cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of R7 cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010124", "l": "phenylacetate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phenylacetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051838", "l": "cytolysis by host of symbiont cells", "d": ["The killing by an organism of a cell in its symbiont organism by means of the rupture of cell membranes and the loss of cytoplasm. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902805", "l": "positive regulation of synaptic vesicle transport", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0001678", "l": "intracellular glucose homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of glucose within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903886", "l": "positive regulation of chemokine (C-C motif) ligand 20 production", "d": ["Any process that activates or increases the frequency, rate or extent of chemokine (C-C motif) ligand 20 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:1902806", "l": "regulation of cell cycle G1/S phase transition", "d": ["Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070980", "l": "biphenyl catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044078", "l": "positive regulation by symbiont of host receptor-mediated endocytosis", "d": ["Any process in which a symbiont organism activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019645", "l": "anaerobic electron transport chain", "d": ["A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors other than oxygen to generate a transmembrane electrochemical gradient."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001299", "l": "N(omega),N(omega)-dimethyl-L-arginine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905149", "l": "positive regulation of smooth muscle hypertrophy", "d": ["Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009823", "l": "cytokinin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cytokinins, a class of adenine-derived compounds that can function in plants as plant growth regulators."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0062237", "l": "protein localization to postsynapse", "d": ["Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.871876592857262", "identifiers": [{"i": "GO:0035710", "l": "CD4-positive, alpha-beta T cell activation", "d": ["The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070305", "l": "response to cGMP", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.655739316124155", "identifiers": [{"i": "GO:0007626", "l": "locomotory behavior", "d": ["The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033546", "l": "myo-inositol hexakisphosphate biosynthetic process, via inositol 1,3,4-trisphosphate", "d": ["The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C; in this pathway, inositol 1,4,5-trisphosphate is first converted to inositol 1,3,4-trisphosphate, and then phosphorylated further."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0051095", "l": "regulation of helicase activity", "d": ["Any process that modulates the frequency, rate or extent of helicase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032929", "l": "negative regulation of superoxide anion generation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0015851", "l": "nucleobase transport", "d": ["The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061145", "l": "lung smooth muscle development", "d": ["The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010751", "l": "negative regulation of nitric oxide mediated signal transduction", "d": ["Any process that decreases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060960", "l": "cardiac neuron fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905735", "l": "regulation of L-proline import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of L-proline import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0016973", "l": "poly(A)+ mRNA export from nucleus", "d": ["The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902664", "l": "positive regulation of peptidyl-L-cysteine S-palmitoylation", "d": ["Any process that activates or increases the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901818", "l": "beta-zeacarotene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-zeacarotene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903810", "l": "L-histidine import across plasma membrane", "d": ["The directed movement of L-histidine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902283", "l": "negative regulation of primary amine oxidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of primary amine oxidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0098781", "l": "ncRNA transcription", "d": ["The transcription of non (protein) coding RNA from a DNA template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901251", "l": "positive regulation of lung goblet cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of lung goblet cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900666", "l": "positive regulation of emodin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of emodin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0048316", "l": "seed development", "d": ["The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051634", "l": "inhibition of acetylcholine uptake", "d": ["Any process that prevents the activation of the directed movement of acetylcholine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071846", "l": "actin filament debranching", "d": ["An actin filament severing process that results in the removal of actin filament branches specifically at the branch points."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.415093686714229", "identifiers": [{"i": "GO:0002712", "l": "regulation of B cell mediated immunity", "d": ["Any process that modulates the frequency, rate, or extent of B cell mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097117", "l": "guanylate kinase-associated protein clustering", "d": ["The clustering process in which guanylate kinase-associated proteins (GKAPs) are localized to distinct domains in the cell membrane. GKAP facilitates assembly of the post synaptic density of neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052644", "l": "chlorophyllide a metabolic process", "d": ["The chemical reactions and pathways involving chlorophyllide a, a chlorophyll lacking the terpenoid side chain, which is the functional parent of chlorophyll a."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000853", "l": "negative regulation of corticosterone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of corticosterone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016062", "l": "adaptation of rhodopsin mediated signaling", "d": ["The process in which a rhodopsin-mediated signaling pathway is adjusted to modulate the sensitivity and response of a visual system to light stimuli (that might vary over more than 6 magnitudes in intensity) without response saturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904148", "l": "cellular response to nonylphenol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019530", "l": "taurine metabolic process", "d": ["The chemical reactions and pathways involving taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032732", "l": "positive regulation of interleukin-1 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-1 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900797", "l": "cordyol C metabolic process", "d": ["The chemical reactions and pathways involving cordyol C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098628", "l": "peptidyl-N-phospho-arginine dephosphorylation", "d": ["The removal of phosphate residues from peptidyl-N-phospho-arginine to form peptidyl-arginine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1902145", "l": "regulation of response to cell cycle checkpoint signaling", "d": ["Any process that modulates the frequency, rate or extent of response to cell cycle checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055045", "l": "antipodal cell degeneration", "d": ["The process in which the antipodal cells undergo programmed cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904638", "l": "response to resveratrol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048567", "l": "ectodermal digestive tract morphogenesis", "d": ["The process in which the anatomical structures of the ectodermal digestive tract are generated and organized. The ectodermal digestive tract includes those portions of the digestive tract that are derived from ectoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902171", "l": "regulation of tocopherol cyclase activity", "d": ["Any process that modulates the frequency, rate or extent of tocopherol cyclase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001929", "l": "negative regulation of exocyst assembly", "d": ["Any process that stops, prevents, or reduces the rate or extent of exocyst assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032675", "l": "regulation of interleukin-6 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-6 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905703", "l": "negative regulation of inhibitory synapse assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory synapse assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034205", "l": "amyloid-beta formation", "d": ["The generation of amyloid-beta by cleavage of the amyloid precursor protein (APP)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060369", "l": "positive regulation of Fc receptor mediated stimulatory signaling pathway", "d": ["Any process that increases the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018218", "l": "peptidyl-cysteine phosphorylation", "d": ["The phosphorylation of peptidyl-cysteine to form peptidyl-S-phospho-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032430", "l": "positive regulation of phospholipase A2 activity", "d": ["Any process that activates or increases the activity of the enzyme phospholipase A2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001699", "l": "acetylcholine-induced gastric acid secretion", "d": ["The regulated release of gastric acid by parietal cells in response to acetylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010221", "l": "negative regulation of vernalization response", "d": ["Any process that stops, prevents or reduces the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048660", "l": "regulation of smooth muscle cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0075294", "l": "positive regulation by symbiont of entry into host", "d": ["Any process that activates or increases the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031887", "l": "lipid droplet transport along microtubule", "d": ["The directed movement of a lipid droplet along a microtubule, mediated by motor proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018411", "l": "protein glucuronidation", "d": ["The modification of a protein by amino acid glucuronidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0097734", "l": "extracellular exosome biogenesis", "d": ["The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097282", "l": "immunoglobulin-mediated neutralization", "d": ["The inhibition of an antigen's biological effects by antibody binding to it. An example is neutralization of diphtheria toxin by preventing its entry into human cells via the binding of antibody specific for diphtheria toxin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990823", "l": "response to leukemia inhibitory factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1901072", "l": "glucosamine-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucosamine-containing compounds (glucosamines)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0046889", "l": "positive regulation of lipid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097111", "l": "endoplasmic reticulum-Golgi intermediate compartment organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER)-Golgi intermediate compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032212", "l": "positive regulation of telomere maintenance via telomerase", "d": ["Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070871", "l": "cell wall organization involved in conjugation with cellular fusion", "d": ["A process of cell wall organization that contributes to conjugation with cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090383", "l": "phagosome acidification", "d": ["Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904706", "l": "negative regulation of vascular associated smooth muscle cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904040", "l": "positive regulation of iron export across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903701", "l": "substantia propria of cornea development", "d": ["The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000975", "l": "positive regulation of pro-B cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of pro-B cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900686", "l": "regulation of gerfelin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of gerfelin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904335", "l": "regulation of ductus arteriosus closure", "d": ["Any process that modulates the frequency, rate or extent of ductus arteriosus closure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0061912", "l": "selective autophagy", "d": ["The macroautophagy process in which specific structures are targeted by the autophagy process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000363", "l": "positive regulation of prostaglandin-E synthase activity", "d": ["Any process that activates or increases the frequency, rate or extent of prostaglandin-E synthase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0062094", "l": "stomach development", "d": ["The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0035307", "l": "positive regulation of protein dephosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0086010", "l": "membrane depolarization during action potential", "d": ["The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097238", "l": "cellular response to methylglyoxal", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051622", "l": "negative regulation of norepinephrine uptake", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.824318789188837", "identifiers": [{"i": "GO:0042214", "l": "terpene metabolic process", "d": ["The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009135", "l": "purine nucleoside diphosphate metabolic process", "d": ["The chemical reactions and pathways involving purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052702", "l": "cellular modified histidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046014", "l": "negative regulation of T cell homeostatic proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0002495", "l": "antigen processing and presentation of peptide antigen via MHC class II", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0090031", "l": "positive regulation of steroid hormone biosynthetic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002078", "l": "membrane fusion involved in acrosome reaction", "d": ["The fusion of the plasma membrane of the sperm with the outer acrosomal membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903000", "l": "regulation of lipid transport across blood-brain barrier", "d": ["Any process that modulates the frequency, rate or extent of lipid transport across blood-brain barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015782", "l": "CMP-N-acetylneuraminate transmembrane transport", "d": ["The directed movement of CMP-N-acetylneuraminate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062209", "l": "spatial regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination", "d": ["Any process that modulates the distribution of sites along the chromosome where meiotic DNA double-strand break formation takes place as part of reciprocal meiotic recombination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002071", "l": "glandular epithelial cell maturation", "d": ["The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072247", "l": "metanephric glomerular parietal epithelial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.115164699299683", "identifiers": [{"i": "GO:0007127", "l": "meiosis I", "d": ["The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007486", "l": "imaginal disc-derived female genitalia development", "d": ["The process whose specific outcome is the progression of the female genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048744", "l": "negative regulation of skeletal muscle fiber development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140526", "l": "double membrane vesicle viral factory assembly", "d": ["A process that results in the assembly of a cytoplasmic viral factory consisting of a double-membrane bound vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120320", "l": "lateral pseudopodium retraction", "d": ["The myosin-based contraction and retraction of a lateral pseudopodium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052783", "l": "reuteran metabolic process", "d": ["The chemical reactions and pathways involving reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035769", "l": "B cell chemotaxis across high endothelial venule", "d": ["The movement of a B cell to cross a high endothelial venule in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019700", "l": "organic phosphonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Catabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0035844", "l": "cloaca development", "d": ["The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902044", "l": "regulation of Fas signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of Fas signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060481", "l": "lobar bronchus epithelium development", "d": ["The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036304", "l": "umbilical cord morphogenesis", "d": ["The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036292", "l": "DNA rewinding", "d": ["The process in which interchain hydrogen bonds between two single-stranded DNA (ssDNA) are reformed to regenerate double-stranded DNA (dsDNA). ssDNA is often bound and stabilized by proteins such as replication protein A (RPA) to form ssDNA bubbles. The bubbles can be rewound by ATP-dependent motors to reform base pairs between strands and thus dsDNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000092", "l": "positive regulation of mesonephric glomerular mesangial cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0006367", "l": "transcription initiation at RNA polymerase II promoter", "d": ["A transcription initiation process that takes place at a RNA polymerase II gene promoter. Messenger RNAs (mRNA) genes, as well as some non-coding RNAs, are transcribed by RNA polymerase II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0070734", "l": "histone H3-K27 methylation", "d": ["The modification of histone H3 by addition of one or more methyl groups to lysine at position 27 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003165", "l": "Purkinje myocyte development", "d": ["The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010513", "l": "positive regulation of phosphatidylinositol biosynthetic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045843", "l": "negative regulation of striated muscle tissue development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0002759", "l": "regulation of antimicrobial humoral response", "d": ["Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "43.680550892515043", "identifiers": [{"i": "GO:0007600", "l": "sensory perception", "d": ["The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903755", "l": "positive regulation of SUMO transferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of SUMO transferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0140480", "l": "mitotic spindle pole body insertion into the nuclear envelope", "d": ["A process in which the duplicated mitotic spindle pole body is inserted into a fenestra which opens in the nuclear envelope in early mitosis, and is subsequently tethered to the membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904907", "l": "regulation of maintenance of mitotic sister chromatid cohesion, telomeric", "d": ["Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0014854", "l": "response to inactivity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inactivity stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0010906", "l": "regulation of glucose metabolic process", "d": ["Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015731", "l": "3-hydroxyphenyl propanoate transport", "d": ["The directed movement of 3-hydroxyphenyl propanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070163", "l": "regulation of adiponectin secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of adiponectin from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0072402", "l": "response to DNA integrity checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of DNA integrity checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075277", "l": "positive regulation of telium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010106", "l": "cellular response to iron ion starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070240", "l": "negative regulation of activated T cell autonomous cell death", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of activated T cell autonomous cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010029", "l": "regulation of seed germination", "d": ["Any process that modulates the frequency, rate or extent of seed germination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0052019", "l": "modulation by symbiont of host hormone or growth regulator levels", "d": ["The alteration by an organism of the levels of hormones or growth regulators in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051629", "l": "inhibition of epinephrine uptake", "d": ["Any process that prevents the activation of the directed movement of epinephrine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110139", "l": "negative regulation of imaginal disc-derived leg joint morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905523", "l": "positive regulation of macrophage migration", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903518", "l": "positive regulation of single strand break repair", "d": ["Any process that activates or increases the frequency, rate or extent of single strand break repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.906467658129422", "identifiers": [{"i": "GO:0060322", "l": "head development", "d": ["The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0032373", "l": "positive regulation of sterol transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000552", "l": "negative regulation of T-helper 2 cell cytokine production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 2 cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904521", "l": "negative regulation of myofibroblast cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901633", "l": "negative regulation of synaptic vesicle membrane organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle membrane organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0097384", "l": "cellular lipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipids, as carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006735", "l": "NADH regeneration", "d": ["A metabolic process that generates a pool of NADH by the reduction of NAD+."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009182", "l": "purine deoxyribonucleoside diphosphate metabolic process", "d": ["The chemical reactions and pathways involving purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033505", "l": "floor plate morphogenesis", "d": ["The process in which the anatomical structure of the floor plate is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019257", "l": "4-nitrotoluene metabolic process", "d": ["The chemical reactions and pathways involving 4-nitrotoluene, 1-methyl-4-nitrobenzene. It is a light yellow liquid with a weak aromatic odor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0031919", "l": "vitamin B6 transport", "d": ["The directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0001824", "l": "blastocyst development", "d": ["The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018144", "l": "RNA-protein covalent cross-linking", "d": ["The formation of a covalent cross-link between RNA and a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0015750", "l": "pentose transmembrane transport", "d": ["The process in which pentose is transported across a lipid bilayer, from one side of a membrane to the other. A pentose is any aldose with a chain of five carbon atoms in the molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.644186068201407", "identifiers": [{"i": "GO:0040013", "l": "negative regulation of locomotion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051697", "l": "protein delipidation", "d": ["The breakage of covalent bonds to detach lipid groups from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0036508", "l": "protein alpha-1,2-demannosylation", "d": ["The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006349", "l": "regulation of gene expression by genomic imprinting", "d": ["An epigenetic mechanism of regulation of gene expression in which epigenetic modifications (imprints) are established during gametogenesis. For a given gene to show parentally biased expression, the imprint are established exclusively in one of the two parental genomes, thus generating an asymmetry between the maternal and paternal alleles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001290", "l": "hydroperoxide metabolic process", "d": ["The chemical reactions and pathways involving a hydroperoxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035351", "l": "heme transmembrane transport", "d": ["The process in which heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901191", "l": "negative regulation of formation of translation initiation ternary complex", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048312", "l": "intracellular distribution of mitochondria", "d": ["Any process that establishes the spatial arrangement of mitochondria within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901172", "l": "phytoene metabolic process", "d": ["The chemical reactions and pathways involving phytoene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0018107", "l": "peptidyl-threonine phosphorylation", "d": ["The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0051654", "l": "establishment of mitochondrion localization", "d": ["The directed movement of the mitochondrion to a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1904082", "l": "pyrimidine nucleobase transmembrane transport", "d": ["The process in which pyrimidine is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032429", "l": "regulation of phospholipase A2 activity", "d": ["Any process that modulates the activity of the enzyme phospholipase A2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0006274", "l": "DNA replication termination", "d": ["The process in which DNA replication at a replication fork ceases; occurs when the replication fork reaches a specific termination site or when two replication forks meet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032099", "l": "negative regulation of appetite", "d": ["Any process that reduces appetite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010750", "l": "positive regulation of nitric oxide mediated signal transduction", "d": ["Any process that increases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031914", "l": "negative regulation of synaptic plasticity", "d": ["A process that decreases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021751", "l": "salivary nucleus development", "d": ["The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035378", "l": "carbon dioxide transmembrane transport", "d": ["The process in which carbon dioxide (CO2) is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019412", "l": "aerobic respiration, using hydrogen as electron donor", "d": ["The oxidation of hydrogen (H2) to water (H2O), using oxygen (O2) as the electron acceptor. A hydrogenase enzyme binds H2 and the hydrogen atoms are passed through an electron transfer chain to O2 to form water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033962", "l": "P-body assembly", "d": ["The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120326", "l": "appressorium-mediated entry into host", "d": ["Penetration by a symbiont into a host organism via an appressorium. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905096", "l": "positive regulation of apolipoprotein A-I-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046059", "l": "dAMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003121", "l": "epinephrine-mediated vasodilation", "d": ["A vasodilation process resulting from secretion of epinephrine into the bloodstream or released by nerve endings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0033244", "l": "regulation of penicillin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021539", "l": "subthalamus development", "d": ["The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0015886", "l": "heme transport", "d": ["The directed movement of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.623042282429068", "identifiers": [{"i": "GO:2000145", "l": "regulation of cell motility", "d": ["Any process that modulates the frequency, rate or extent of cell motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0006693", "l": "prostaglandin metabolic process", "d": ["The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0019988", "l": "charged-tRNA amino acid modification", "d": ["The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002847", "l": "negative regulation of T cell tolerance induction to tumor cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction to tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040038", "l": "polar body extrusion after meiotic divisions", "d": ["The cell cycle process in which two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010747", "l": "positive regulation of long-chain fatty acid import across plasma membrane", "d": ["Any process that increases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0090659", "l": "walking behavior", "d": ["The behavior of an organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0009065", "l": "glutamine family amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0043557", "l": "regulation of translation in response to osmotic stress", "d": ["Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901148", "l": "gene expression involved in extracellular matrix organization", "d": ["Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0050973", "l": "detection of mechanical stimulus involved in equilibrioception", "d": ["The series of events involved in equilibrioception in which a mechanical stimulus is received and converted into a molecular signal. During equilibrioception, mechanical stimuli may be in the form of input from pressure receptors or from the labyrinth system of the inner ears."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002859", "l": "negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0099505", "l": "regulation of presynaptic membrane potential", "d": ["Any process that modulates the potential difference across a presynaptic membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003059", "l": "positive regulation of the force of heart contraction by epinephrine", "d": ["The process in which the secretion of epinephrine into the bloodstream or released from nerve endings modulates the force of heart muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0042092", "l": "type 2 immune response", "d": ["An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0048247", "l": "lymphocyte chemotaxis", "d": ["The directed movement of a lymphocyte in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905492", "l": "positive regulation of branching morphogenesis of a nerve", "d": ["Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019515", "l": "lactose catabolic process via UDP-galactose", "d": ["The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate UDP-galactose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905186", "l": "regulation of metaphase/anaphase transition of meiosis I", "d": ["Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904759", "l": "protein localization to equatorial microtubule organizing center", "d": ["A process in which a protein is transported to, or maintained in, a location within an equatorial microtubule organizing center."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006780", "l": "uroporphyrinogen III biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of uroporphyrinogen III."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033986", "l": "response to methanol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:1905031", "l": "regulation of membrane repolarization during cardiac muscle cell action potential", "d": ["Any process that modulates the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0052708", "l": "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process", "d": ["The chemical reactions and pathways involving N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.358732272612386", "identifiers": [{"i": "GO:0071897", "l": "DNA biosynthetic process", "d": ["The biosynthetic process resulting in the formation of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902443", "l": "negative regulation of ripoptosome assembly involved in necroptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0006551", "l": "leucine metabolic process", "d": ["The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.161881760686384", "identifiers": [{"i": "GO:0007613", "l": "memory", "d": ["The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0006037", "l": "cell wall chitin metabolic process", "d": ["The chemical reactions and pathways involving cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018020", "l": "peptidyl-glutamic acid methylation", "d": ["The addition of a methyl group to a glutamic acid residue in a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040018", "l": "positive regulation of multicellular organism growth", "d": ["Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061771", "l": "response to caloric restriction", "d": ["A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caloric restriction, insufficient food energy intake."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0044241", "l": "lipid digestion", "d": ["The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000950", "l": "positive regulation of xyloglucan metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of xyloglucan metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902114", "l": "D-valine metabolic process", "d": ["The chemical reactions and pathways involving D-valine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000017", "l": "positive regulation of determination of dorsal identity", "d": ["Any process that activates or increases the frequency, rate or extent of determination of dorsal identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0072262", "l": "metanephric glomerular mesangial cell proliferation involved in metanephros development", "d": ["The multiplication or reproduction of glomerular mesangial cells in the metanephros, resulting in the expansion of the population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0055127", "l": "vibrational conductance of sound to the inner ear", "d": ["The transmission of vibrations via ossicles to the inner ear."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033272", "l": "myo-inositol hexakisphosphate transport", "d": ["The directed movement of myo-inositol hexakisphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901366", "l": "funalenone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of funalenone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0021590", "l": "cerebellum maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902327", "l": "bacterial-type DNA replication DNA ligation", "d": ["Any DNA ligation that is involved in bacterial-type DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000987", "l": "positive regulation of behavioral fear response", "d": ["Any process that activates or increases the frequency, rate or extent of behavioral fear response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000921", "l": "regulation of arabinoxylan-containing compound catabolic process", "d": ["Any process that modulates the frequency, rate or extent of arabinoxylan-containing compound catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0000423", "l": "mitophagy", "d": ["The selective autophagy process in which a mitochondrion is degraded by macroautophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0045835", "l": "negative regulation of meiotic nuclear division", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0072273", "l": "metanephric nephron morphogenesis", "d": ["The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904826", "l": "regulation of hydrogen sulfide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of hydrogen sulfide biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051626", "l": "regulation of epinephrine uptake", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter epinephrine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0000012", "l": "single strand break repair", "d": ["The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.281967957033203", "identifiers": [{"i": "GO:0002286", "l": "T cell activation involved in immune response", "d": ["The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905411", "l": "positive regulation of mitotic cohesin unloading", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cohesin unloading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003305", "l": "cell migration involved in heart jogging", "d": ["The orderly movement of a cell of the myocardium from one site to another that will contribute to heart jogging."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032959", "l": "inositol trisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of inositol trisphosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901445", "l": "regulation of response to propan-1-ol", "d": ["Any process that modulates the frequency, rate or extent of response to propan-1-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0051326", "l": "telophase", "d": ["The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903529", "l": "negative regulation of dCDP biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dCDP biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902897", "l": "regulation of postsynaptic density protein 95 clustering", "d": ["Any process that modulates the frequency, rate or extent of postsynaptic density protein 95 clustering."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903241", "l": "U2-type prespliceosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an U2-type prespliceosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048735", "l": "haltere morphogenesis", "d": ["The process in which the anatomical structures of a haltere are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031131", "l": "reception of an inductive signal", "d": ["The process in which one cell or group of cells receives, transduces, and responds to a signal generated by another cell or group of cells of different ancestry and developmental potential, such that the recipient cell(s) undergo a developmental change."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009230", "l": "thiamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904014", "l": "response to serotonin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141064", "l": "zygotic genome activation", "d": ["A process that contributes to the onset of de novo transcription from the zygotic genome as part of the maternal-to-zygote transition in gene expression. The zygote overcomes the silencing that has been established. The cause of this silencing could be due to several factors: chromatin modifications leading to repression, or lack of adequate transcription machinery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.200596633389878", "identifiers": [{"i": "GO:0002263", "l": "cell activation involved in immune response", "d": ["A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006726", "l": "eye pigment biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039573", "l": "suppression by virus of host complement activation", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of complement activation. The activation of complement involves the sequential proteolysis of proteins to generate enzymes with catalytic activities. The biological functions of the complement include opsonization, inflammation, lysis of immune complexes, or enhancement of the humoral immune response. For example, the virus complement control protein (VCP) of vaccinia virus, and the complement control protein of herpesvirus inhibit C3 convertase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1901440", "l": "poly(hydroxyalkanoate) metabolic process", "d": ["The chemical reactions and pathways involving poly(hydroxyalkanoate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034054", "l": "suppression by symbiont of host defense-related programmed cell death", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002045", "l": "regulation of cell adhesion involved in intussusceptive angiogenesis", "d": ["The process that modulates the frequency, rate or extent of attachment of a blood vessel endothelial cell to another cell or to the extracellular matrix involved in intussusceptive angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070711", "l": "RNA adenosine-uridine insertion", "d": ["The modification of an RNA molecule by insertion of an adenosine-uridine dinucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1902423", "l": "regulation of attachment of mitotic spindle microtubules to kinetochore", "d": ["Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090373", "l": "negative regulation of glycerol transport", "d": ["Any process that decreases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904744", "l": "positive regulation of telomeric DNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of telomeric DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0042058", "l": "regulation of epidermal growth factor receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905409", "l": "positive regulation of creatine transmembrane transporter activity", "d": ["Any process that activates or increases the frequency, rate or extent of creatine transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010036", "l": "response to boron-containing substance", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a boron-containing substance stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019507", "l": "pyridine metabolic process", "d": ["The chemical reactions and pathways involving pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031536", "l": "positive regulation of exit from mitosis", "d": ["Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032472", "l": "Golgi calcium ion transport", "d": ["The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090129", "l": "positive regulation of synapse maturation", "d": ["Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905341", "l": "negative regulation of protein localization to kinetochore", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to kinetochore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006198", "l": "cAMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000716", "l": "transcription-coupled nucleotide-excision repair, DNA damage recognition", "d": ["The identification of lesions on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0001990", "l": "regulation of systemic arterial blood pressure by hormone", "d": ["The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002308", "l": "CD8-positive, alpha-beta cytotoxic T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120236", "l": "negative regulation of post-translational protein targeting to membrane, translocation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of posttranslational protein translocation through the ER membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042918", "l": "alkanesulfonate transport", "d": ["The directed movement of an alkanesulfonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanesulfonates are organic esters or salts of sulfonic acid containing an aliphatic hydrocarbon radical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0003027", "l": "regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling", "d": ["The process that modulates blood pressure by the action of chemoreceptors found in the carotid bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075292", "l": "negative regulation of aplanospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0055070", "l": "copper ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of copper ions within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009945", "l": "radial axis specification", "d": ["The establishment, maintenance and elaboration of an axis that initiates at a point and radiates outward from the point."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098931", "l": "virion attachment to host cell flagellum", "d": ["The process by which a virion attaches to a the host cell flagellum. Some DNA bacterial viruses use flagella to attach to the host cell. This contact with the flagellum facilitates concentration of phage particles around the entry receptor on the bacterial cell surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0017179", "l": "peptidyl-diphthine metabolic process", "d": ["The chemical reactions and pathways involving peptidyl-diphthine, a modified histidine residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046203", "l": "spermidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of spermidine, N-(3-aminopropyl)-1,4-diaminobutane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0009723", "l": "response to ethylene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036353", "l": "histone H2A-K119 monoubiquitination", "d": ["The modification of histone H2A by addition of a single ubiquitin group to lysine-119 (H2A- K119) in metazoans, and at the equivalent residue in other organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045701", "l": "negative regulation of spermatid nuclear differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140915", "l": "zinc ion import into zymogen granule", "d": ["The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a zymogen granule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006076", "l": "(1->3)-beta-D-glucan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (1->3)-beta-D-glucans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0010717", "l": "regulation of epithelial to mesenchymal transition", "d": ["Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140725", "l": "detoxification of free heme", "d": ["Any process that reduces or removes the toxicity of free heme. These include transport of heme away from sensitive areas and to compartments or complexes whose purpose is sequestration of heme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000697", "l": "negative regulation of epithelial cell differentiation involved in kidney development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061765", "l": "modulation by virus of host NIK/NF-kappaB cascade", "d": ["Any process in which a virus effect a change in the frequency, rate or extent of NIK/NF-kappaB signaling in the host."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.003741351937961", "identifiers": [{"i": "GO:0021536", "l": "diencephalon development", "d": ["The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904710", "l": "positive regulation of granulosa cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of granulosa cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902334", "l": "fructose export from vacuole to cytoplasm", "d": ["The directed movement of fructose from vacuole to cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048918", "l": "posterior lateral line nerve development", "d": ["The process whose specific outcome is the progression of the posterior lateral line nerve over time, from its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0051325", "l": "interphase", "d": ["The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0071305", "l": "cellular response to vitamin D", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097326", "l": "melanocyte adhesion", "d": ["The attachment of a melanocyte to another cell via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901535", "l": "regulation of DNA demethylation", "d": ["Any process that modulates the frequency, rate or extent of DNA demethylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033234", "l": "negative regulation of protein sumoylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904624", "l": "regulation of glycine secretion, neurotransmission", "d": ["Any process that modulates the frequency, rate or extent of glycine secretion, neurotransmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045197", "l": "establishment or maintenance of epithelial cell apical/basal polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0019055", "l": "modification by virus of host cell cycle regulation", "d": ["Interactions, directly with the host cell macromolecular machinery, to allow a virus to modulate the rate of the host cell cycle to facilitate virus replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097316", "l": "cellular response to N-acetyl-D-glucosamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0005992", "l": "trehalose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1902101", "l": "positive regulation of metaphase/anaphase transition of cell cycle", "d": ["Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061520", "l": "Langerhans cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a Langerhans cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002856", "l": "negative regulation of natural killer cell mediated immune response to tumor cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060358", "l": "negative regulation of leucine import", "d": ["Any process that decreases the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0106005", "l": "RNA 5'-cap (guanine-N7)-methylation", "d": ["The process whereby a guanine in 5-cap is methylated at the N7 position of guanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099051", "l": "vesicle scission involved in endocytosis", "d": ["The membrane scission process that is the final step in the formation of an endocytic vesicle: separation from the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019927", "l": "peptide cross-linking via 4'-(S-L-cysteinyl)-L-tryptophyl quinone", "d": ["The cross-linking of a cysteine residue to tryptophyl quinone to form 4'-(S-L-cysteinyl)-L-tryptophyl quinone, a cofactor found at the active site of amine dehydrogenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140331", "l": "aminophospholipid translocation", "d": ["The movement of an aminophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.426153789046865", "identifiers": [{"i": "GO:0060993", "l": "kidney morphogenesis", "d": ["Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018396", "l": "peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine", "d": ["The hydroxylation of peptidyl-lysine to peptidyl-4-hydroxy-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035819", "l": "positive regulation of renal sodium excretion by pressure natriuresis", "d": ["An increase in the amount of sodium excreted in urine over a unit of time, as a result of pressure natriuresis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032884", "l": "regulation of cell wall chitin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cell wall chitin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905372", "l": "ceramide phosphoethanolamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ceramide phosphoethanolamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031524", "l": "menthol metabolic process", "d": ["The chemical reactions and pathways involving menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902779", "l": "cellular response to alkane", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018361", "l": "peptidyl-glutamine 2-methylation", "d": ["The methylation of glutamine to form 2-methyl-L-glutamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031144", "l": "proteasome localization", "d": ["Any process in which the proteasome is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045905", "l": "positive regulation of translational termination", "d": ["Any process that activates or increases the frequency, rate or extent of translational termination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015694", "l": "mercury ion transport", "d": ["The directed movement of mercury (Hg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070159", "l": "mitochondrial threonyl-tRNA aminoacylation", "d": ["The process of coupling threonine to threonyl-tRNA in a mitochondrion, catalyzed by threonyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061635", "l": "regulation of protein complex stability", "d": ["Any process that affects the structure and integrity of a protein complex by altering the likelihood of its assembly or disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900186", "l": "negative regulation of clathrin-dependent endocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-mediated endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0051570", "l": "regulation of histone H3-K9 methylation", "d": ["Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001111", "l": "positive regulation of lens epithelial cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of lens epithelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071329", "l": "cellular response to sucrose stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061003", "l": "positive regulation of dendritic spine morphogenesis", "d": ["Any process that increases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0001837", "l": "epithelial to mesenchymal transition", "d": ["A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0008363", "l": "larval chitin-based cuticle development", "d": ["Synthesis and deposition of a chitin-based larval cuticle. The insect larval cuticle is a secretion from epidermal cells that is shed at each molt. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048463", "l": "carpel structural organization", "d": ["The process that contributes to the act of creating the structural organization of the carpel. This process pertains to the physical shaping of a rudimentary structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0071999", "l": "extracellular polysaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of polysaccharides used in extracellular structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090719", "l": "adaptive immune effector response involving T cells and B lineage cells", "d": ["An adaptive immune effector response involving T cells and B lineage cells. In the case of B lineage cells, the effector cells are the antibody secreting plasma cells whereas for T cells the effector cells may be helper T cells or cytotoxic T cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.523981342372721", "identifiers": [{"i": "GO:0006914", "l": "autophagy", "d": ["The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990145", "l": "maintenance of translational fidelity", "d": ["Suppression of the occurrence of translational errors, such as codon-anticodon mis-paring, during the process of translation of a protein using an mRNA template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080193", "l": "diffuse secondary thickening", "d": ["Lateral growth of the older parts of a stem that occurs when the central parenchyma cells and the not yet fully differentiated fiber cells of the bundle sheaths continue to undergo cell division and expansion for a long period of time, leading to an increase in girth of the stem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062010", "l": "primitive palate development", "d": ["The biological process whose specific outcome is the progression of the primitive palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0048538", "l": "thymus development", "d": ["The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075303", "l": "positive regulation of basidiospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042725", "l": "thiamine-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), and compounds derived from it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052776", "l": "diacetylchitobiose catabolic process to glucosamine and acetate", "d": ["The pathway resulting in the breakdown of diacetylchitobiose into simpler products, including glucosamine and glucosamine. The catabolism proceeds by the deacetylation of diacetylchitobiose, producing acetate and GlcN-GlcNAc; the latter is cleaved to produce glucosamine (GlcN) and N-acetylglucosamine (GlcNAc). The N-acetylglucosamine (GlcNAc) is then deacetylated to produce glucosamine (GlcN) and acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021779", "l": "oligodendrocyte cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into an oligodendrocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002782", "l": "antifungal peptide secretion", "d": ["The regulated release of an antifungal peptide from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060515", "l": "prostate field specification", "d": ["The process that results in the delineation of a specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0022007", "l": "convergent extension involved in neural plate elongation", "d": ["The process of directed cell movement in the neural plate resulting in tissue elongation via intercalation of adjacent cells in an epithelial sheet at the midline, leading to narrowing and lengthening of the neural plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035783", "l": "CD4-positive, alpha-beta T cell costimulation", "d": ["The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060305", "l": "regulation of cell diameter", "d": ["Any process that modulates the diameter of a cell, the length of a line segment that crosses through the center of a circular section through a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0050805", "l": "negative regulation of synaptic transmission", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071662", "l": "negative regulation of granzyme B production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granzyme B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.566286445527851", "identifiers": [{"i": "GO:0090087", "l": "regulation of peptide transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000373", "l": "positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity", "d": ["Any process that activates or increases the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061691", "l": "detoxification of hydrogen peroxide", "d": ["Any process that reduces or removes the toxicity of hydrogen peroxide. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030514", "l": "negative regulation of BMP signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0060119", "l": "inner ear receptor cell development", "d": ["The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046739", "l": "transport of virus in multicellular host", "d": ["The transport of a virus between cells in a multicellular organism. The cells can be adjacent or spatially separated (e.g. in different tissues or organs)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036527", "l": "peptidyl-arginine deglycation", "d": ["The removal of a sugar or dicarbonyl from an arginine residue of a glycated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046042", "l": "ITP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ITP, inosine triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071591", "l": "nicotinic acid riboside metabolic process", "d": ["The chemical reactions and pathways involving nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902226", "l": "regulation of macrophage colony-stimulating factor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006624", "l": "vacuolar protein processing", "d": ["Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106304", "l": "mannogen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001090", "l": "maltotriulose transport", "d": ["The directed movement of a maltotriuloseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006515", "l": "protein quality control for misfolded or incompletely synthesized proteins", "d": ["The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075009", "l": "germ tube formation", "d": ["Development of slender tubular outgrowth first produced by most symbiont spores immediately following germination on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002908", "l": "regulation of peripheral B cell deletion", "d": ["Any process that modulates the frequency, rate, or extent of peripheral B cell deletion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031447", "l": "negative regulation of fast-twitch skeletal muscle fiber contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of fast-twitch skeletal muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900343", "l": "negative regulation of methane biosynthetic process from dimethyl sulfide", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903984", "l": "positive regulation of TRAIL-activated apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900170", "l": "negative regulation of glucocorticoid mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072194", "l": "kidney smooth muscle tissue development", "d": ["The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046884", "l": "follicle-stimulating hormone secretion", "d": ["The regulated release of follicle-stimulating hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000550", "l": "negative regulation of B cell chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of B cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051164", "l": "L-xylitol metabolic process", "d": ["The chemical reactions and pathways involving L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group. It is as sweet as sucrose and is used as a noncariogenic sweetner and as a sugar substitute in diabetic diets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035818", "l": "positive regulation of urine volume by pressure natriuresis", "d": ["An increase in the amount of urine excreted over a unit of time, as a result of pressure natriuresis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.689405974145266", "identifiers": [{"i": "GO:0015833", "l": "peptide transport", "d": ["The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0034410", "l": "cell wall beta-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001314", "l": "UDP-4-deoxy-4-formamido-beta-L-arabinopyranose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010432", "l": "bract development", "d": ["The process whose specific outcome is the progression of the bract over time, from its formation to the mature structure. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061978", "l": "mandibular condyle articular cartilage development", "d": ["The process whose specific outcome is the progression of mandibular joint condyle articular cartilage over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900901", "l": "positive regulation of heptadecane metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of heptadecane metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035319", "l": "imaginal disc-derived wing hair elongation", "d": ["Growth of a prehair in the approximately 10 hour period following its emergence from an epidermal cell in an imaginal disc-derived wing. Prehair elongation is guided and/or driven by the polymerization of actin filaments and the orderly crosslinking of filaments into bundles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033342", "l": "negative regulation of collagen binding", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of collagen binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019347", "l": "GDP-alpha-D-mannosylchitobiosyldiphosphodolichol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:1903350", "l": "response to dopamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070800", "l": "negative regulation of conidiophore stalk development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051639", "l": "actin filament network formation", "d": ["The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019260", "l": "1,2-dichloroethane catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106109", "l": "positive regulation of (R)-mevalonic acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of (R)-mevalonic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120273", "l": "ciliary centrin arm assembly", "d": ["The aggregation, arrangement and bonding together of a set of macromolecules to form a ciliary centrin arm, a rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046689", "l": "response to mercury ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019369", "l": "arachidonic acid metabolic process", "d": ["The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001969", "l": "regulation of activation of membrane attack complex", "d": ["Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1903665", "l": "negative regulation of asexual reproduction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of asexual reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0031110", "l": "regulation of microtubule polymerization or depolymerization", "d": ["Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0031638", "l": "zymogen activation", "d": ["The proteolytic processing of an inactive enzyme to an active form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.115164699299683", "identifiers": [{"i": "GO:0043455", "l": "regulation of secondary metabolic process", "d": ["Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0016132", "l": "brassinosteroid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902054", "l": "negative regulation of neosartoricin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neosartoricin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060681", "l": "branch elongation involved in ureteric bud branching", "d": ["The growth of a branch of the ureteric bud along its axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009696", "l": "salicylic acid metabolic process", "d": ["The chemical reactions and pathways involving of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0009954", "l": "proximal/distal pattern formation", "d": ["The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1905134", "l": "positive regulation of meiotic chromosome separation", "d": ["Any process that activates or increases the frequency, rate or extent of meiotic chromosome separation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032359", "l": "provirus excision", "d": ["The molecular events that lead to the excision of a viral genome from the host genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021813", "l": "cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration", "d": ["The interaction between two cells that modulates the association of a neuronal cell and a glial cell involved in glial-mediated radial cell migration in the cerebral cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061226", "l": "proximal/distal pattern formation involved in mesonephric nephron development", "d": ["The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the mesonephros. The proximal/distal axis is defined by a line that runs from the glomerulus (proximal end) outward toward the mesonephric duct (distal end)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015737", "l": "galacturonate transmembrane transport", "d": ["The process in which galacturonate is transported across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0008216", "l": "spermidine metabolic process", "d": ["The chemical reactions and pathways involving spermidine, N-(3-aminopropyl)-1,4-diaminobutane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0060479", "l": "lung cell differentiation", "d": ["The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048239", "l": "negative regulation of DNA recombination at telomere", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the telomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1905771", "l": "negative regulation of mesodermal cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046013", "l": "regulation of T cell homeostatic proliferation", "d": ["Any process that modulates the frequency, rate or extent of resting T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042323", "l": "negative regulation of circadian sleep/wake cycle, non-REM sleep", "d": ["Any process that stops, prevents or reduces the duration or quality of non-rapid eye movement (NREM) sleep."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034119", "l": "negative regulation of erythrocyte aggregation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte aggregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902442", "l": "regulation of ripoptosome assembly involved in necroptotic process", "d": ["Any process that modulates the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060414", "l": "aorta smooth muscle tissue morphogenesis", "d": ["The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070857", "l": "regulation of bile acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0071624", "l": "positive regulation of granulocyte chemotaxis", "d": ["Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046345", "l": "abscisic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0045676", "l": "regulation of R7 cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of R7 differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:2000035", "l": "regulation of stem cell division", "d": ["Any process that modulates the frequency, rate or extent of stem cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003190", "l": "atrioventricular valve formation", "d": ["The developmental process pertaining to the initial formation of the atrioventricular valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.432445482536949", "identifiers": [{"i": "GO:0006900", "l": "vesicle budding from membrane", "d": ["The evagination of a membrane, resulting in formation of a vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0030516", "l": "regulation of axon extension", "d": ["Any process that modulates the rate, direction or extent of axon extension."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035881", "l": "amacrine cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002692", "l": "negative regulation of cellular extravasation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of cellular extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0150180", "l": "negative regulation of phosphatidylserine metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.152542716964341", "identifiers": [{"i": "GO:0043473", "l": "pigmentation", "d": ["The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:1901214", "l": "regulation of neuron death", "d": ["Any process that modulates the frequency, rate or extent of neuron death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003363", "l": "lamellipodium assembly involved in ameboidal cell migration", "d": ["Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self propelled movement of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030448", "l": "hyphal growth", "d": ["Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060184", "l": "cell cycle switching", "d": ["The process in which a cell switches cell cycle mode."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032337", "l": "positive regulation of activin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060488", "l": "orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis", "d": ["The process in which a lung bud bifurcates perpendicular to the plane of the previous bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090515", "l": "L-glutamate transmembrane import into vacuole", "d": ["The directed movement of L-glutamate into the vacuole across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0002717", "l": "positive regulation of natural killer cell mediated immunity", "d": ["Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045983", "l": "positive regulation of purine nucleobase metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving purine bases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901110", "l": "actinorhodin metabolic process", "d": ["The chemical reactions and pathways involving actinorhodin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "36.884115860171953", "identifiers": [{"i": "GO:0035295", "l": "tube development", "d": ["The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900089", "l": "negative regulation of inositol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of inositol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0014831", "l": "gastro-intestinal system smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048718", "l": "cibarial fish-trap bristle morphogenesis", "d": ["The process in which the anatomical structures of a cibarial fish-trap bristle are generated and organized. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051451", "l": "myoblast migration", "d": ["The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905009", "l": "negative regulation of L-lysine import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-lysine import into cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003360", "l": "brainstem development", "d": ["The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.235616146829116", "identifiers": [{"i": "GO:0031669", "l": "cellular response to nutrient levels", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900287", "l": "positive regulation of cellotriose transport", "d": ["Any process that activates or increases the frequency, rate or extent of cellotriose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140568", "l": "extraction of mislocalized protein from membrane", "d": ["The removal of a mislocalized protein from a cellular membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902046", "l": "positive regulation of Fas signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of Fas signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000083", "l": "negative regulation of L-ascorbic acid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of L-ascorbic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110162", "l": "regulation of mitotic spindle elongation (spindle phase three)", "d": ["Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900109", "l": "regulation of histone H3-K9 dimethylation", "d": ["Any process that modulates the frequency, rate or extent of histone H3-K9 dimethylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:1900619", "l": "acetate ester metabolic process", "d": ["The chemical reactions and pathways involving an acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0017001", "l": "antibiotic catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902057", "l": "(25S)-Delta(4)-dafachronate metabolic process", "d": ["The chemical reactions and pathways involving (25S)-Delta(4)-dafachronate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060166", "l": "olfactory pit development", "d": ["The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098507", "l": "polynucleotide 5' dephosphorylation", "d": ["The process of removing one or more phosphate groups from the 5' end of a polynucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902071", "l": "regulation of hypoxia-inducible factor-1alpha signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902908", "l": "regulation of melanosome transport", "d": ["Any process that modulates the frequency, rate or extent of melanosome transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071283", "l": "cellular response to iron(III) ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.011351901223186", "identifiers": [{"i": "GO:0008016", "l": "regulation of heart contraction", "d": ["Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902971", "l": "mitotic DNA replication DNA duplex unwinding", "d": ["Any DNA duplex unwinding involved in mitotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901621", "l": "negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.26089068872632", "identifiers": [{"i": "GO:0006887", "l": "exocytosis", "d": ["A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900707", "l": "regulation of tensidol A biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of tensidol A biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "47.650478118902939", "identifiers": [{"i": "GO:0022414", "l": "reproductive process", "d": ["A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900077", "l": "negative regulation of cellular response to insulin stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001268", "l": "negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0009310", "l": "amine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901496", "l": "positive regulation of cysteine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cysteine metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0009103", "l": "lipopolysaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000147", "l": "actin cortical patch assembly", "d": ["Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007629", "l": "flight behavior", "d": ["The response to external or internal stimuli that results in the locomotory process of flight. Flight is the self-propelled movement of an organism through the air."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902974", "l": "meiotic DNA replication initiation", "d": ["Any DNA replication initiation involved in meiotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903256", "l": "selenoneine metabolic process", "d": ["The chemical reactions and pathways involving selenoneine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061029", "l": "eyelid development in camera-type eye", "d": ["The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003397", "l": "neuron migration involved in amphid sensory organ dendrite retrograde extension", "d": ["The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite of a neuron in the amphid sensory organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904914", "l": "negative regulation of establishment of protein-containing complex localization to telomere", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:2000737", "l": "negative regulation of stem cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0000045", "l": "autophagosome assembly", "d": ["The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046415", "l": "urate metabolic process", "d": ["The chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060660", "l": "epidermis morphogenesis involved in nipple formation", "d": ["The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009213", "l": "pyrimidine deoxyribonucleoside triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0140354", "l": "lipid import into cell", "d": ["The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:1902577", "l": "protein localization to medial cortical node", "d": ["A process in which a protein is transported to, or maintained in, a location within a medial cortical node."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0052799", "l": "coenzyme F420-dependent bicyclic nitroimidazole catabolic process", "d": ["The breakdown of a bicyclic nitroimidazole into simpler components in a process that requires coenzyme F420 and produces reactive nitrogen species. Hydride, from reduced coenzyme F420, is added to the bicyclic nitroimidazole, resulting in unstable substances that break down to form three stable products. The elimination of nitrous acid produces the corresponding des-nitroimidazole; hydrolysis produces a related compound; and further reduction creates an aromatic hydroxylamine metabolite that degrades further. These reactions release hyponitrous acid and nitrous acid, which is unstable and disproportionates into nitric oxide (NO) and other reactive nitrogen intermediates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000459", "l": "negative regulation of astrocyte chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905443", "l": "regulation of clathrin coat assembly", "d": ["Any process that modulates the frequency, rate or extent of clathrin coat assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001560", "l": "regulation of cell growth by extracellular stimulus", "d": ["Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051632", "l": "negative regulation of acetylcholine uptake", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002246", "l": "wound healing involved in inflammatory response", "d": ["The series of events that restore integrity to damaged tissue that contribute to an inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0070920", "l": "regulation of regulatory ncRNA processing", "d": ["Any process that modulates the frequency, rate or extent of regulatory non-coding RNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097578", "l": "sequestering of copper ion", "d": ["The process of binding or confining copper ions such that they are separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0039008", "l": "pronephric nephron tubule morphogenesis", "d": ["The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:1903173", "l": "fatty alcohol metabolic process", "d": ["The chemical reactions and pathways involving fatty alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140302", "l": "pollen-style interaction", "d": ["The interactions (or cell to cell communication) that occur between the male gametophyte (pollen/pollen tube) and the stylar tissues of the female sporophyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904146", "l": "positive regulation of meiotic cell cycle process involved in oocyte maturation", "d": ["Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002362", "l": "CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment", "d": ["The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a CD4-positive, CD25-positive, alpha-beta regulatory T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019497", "l": "hexachlorocyclohexane metabolic process", "d": ["The chemical reactions and pathways involving hexachlorocyclohexane, a cyclohexane derivative with 6 chlorine atoms attached to the hexane ring. Hexachlorocyclohexane consists of a mixture of 8 different isomers and was used a commercial insecticide. It is persistent in the environment, causing serious soil pollution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021712", "l": "candelabrum cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature candelabrum cell. Differentiation includes the processes involved in commitment of a neuroblast to a candelabrum cell fate. A candelabrum cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0048596", "l": "embryonic camera-type eye morphogenesis", "d": ["The process in which the anatomical structures of the eye are generated and organized during embryonic development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902209", "l": "negative regulation of bacterial-type flagellum assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903085", "l": "regulation of sinapate ester biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of sinapate ester biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900702", "l": "negative regulation of orcinol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of orcinol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990810", "l": "microtubule anchoring at mitotic spindle pole body", "d": ["Any process in which a microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097446", "l": "protein localization to eisosome filament", "d": ["A process in which a protein is transported to, and/or maintained in, a specific location in a eisosome filament (also called linear eisosome), a filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042216", "l": "phenanthrene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006337", "l": "nucleosome disassembly", "d": ["The controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003100", "l": "regulation of systemic arterial blood pressure by endothelin", "d": ["The process in which endothelin modulates the force with which blood passes through the circulatory system. Endothelin is a hormone that is released by the endothelium, and it is a vasoconstrictor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903189", "l": "glyoxal metabolic process", "d": ["The chemical reactions and pathways involving glyoxal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904927", "l": "cellular response to palmitoleic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060504", "l": "positive regulation of epithelial cell proliferation involved in lung bud dilation", "d": ["Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung bud increasing in size radially."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900055", "l": "regulation of leaf senescence", "d": ["Any process that modulates the frequency, rate or extent of leaf senescence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000085", "l": "negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003098", "l": "tubuloglomerular feedback", "d": ["The process in which blood volume is regulated due to a change in the rate of glomerular filtration. This is accomplished by a feedback mechanism that senses changes in the juxtaglomerular apparatus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060125", "l": "negative regulation of growth hormone secretion", "d": ["Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0002711", "l": "positive regulation of T cell mediated immunity", "d": ["Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019633", "l": "shikimate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042256", "l": "cytosolic ribosome assembly", "d": ["The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional cytosolic ribosome. Distinct stages of this process take place first in the nucleolus, then in the nucleus and finally in the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000102", "l": "negative regulation of mammary stem cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mammary stem cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042758", "l": "long-chain fatty acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a long-chain fatty acid, a fatty acid with an aliphatic tail of 13 to 21 carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.303328383464915", "identifiers": [{"i": "GO:0048593", "l": "camera-type eye morphogenesis", "d": ["The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0003235", "l": "sinus venosus development", "d": ["The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0099171", "l": "presynaptic modulation of chemical synaptic transmission", "d": ["Any process, acting in the presynapse that results in modulation of chemical synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0097576", "l": "vacuole fusion", "d": ["Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904655", "l": "positive regulation of lung alveolus development", "d": ["Any process that activates or increases the frequency, rate or extent of lung alveolus development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0061208", "l": "cell differentiation involved in mesonephros development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035628", "l": "cystic duct development", "d": ["The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gallbladder to the common bile duct."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035284", "l": "brain segmentation", "d": ["Division of the brain into a series of semi-repetitive parts or segments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903437", "l": "negative regulation of mitotic cytokinetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0009086", "l": "methionine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002626", "l": "negative regulation of T cell antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071036", "l": "nuclear polyadenylation-dependent snoRNA catabolic process", "d": ["The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nucleolar RNA (snoRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snoRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0086018", "l": "SA node cell to atrial cardiac muscle cell signaling", "d": ["Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019292", "l": "tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate", "d": ["The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate 4-hydroxyphenylpyruvate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000137", "l": "negative regulation of cell proliferation involved in heart morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0042982", "l": "amyloid precursor protein metabolic process", "d": ["The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046232", "l": "carbazole catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050999", "l": "regulation of nitric-oxide synthase activity", "d": ["Any process that modulates the activity of the enzyme nitric-oxide synthase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002156", "l": "negative regulation of thyroid hormone mediated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of thyroid hormone mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002175", "l": "protein localization to paranode region of axon", "d": ["A cellular protein localization process in which a protein is transported to, or maintained at, the paranode region of an axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046391", "l": "5-phosphoribose 1-diphosphate metabolic process", "d": ["The chemical reactions and pathways involving 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048904", "l": "anterior lateral line neuromast cupula development", "d": ["The process whose specific outcome is the progression of the anterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042820", "l": "vitamin B6 catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003367", "l": "cell-cell adhesion involved in ameboidal cell migration", "d": ["The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044863", "l": "modulation by virus of host cell division", "d": ["Any process where an infecting virus modulates the frequency, rate or extent of the physical partitioning and separation of its host's cell into daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.905555711669919", "identifiers": [{"i": "GO:0043065", "l": "positive regulation of apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000336", "l": "negative regulation of endothelial microparticle formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial microparticle formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010645", "l": "regulation of cell communication by chemical coupling", "d": ["Any process that modulates the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061479", "l": "response to reverse transcriptase inhibitor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reverse transcriptase inhibitor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042989", "l": "sequestering of actin monomers", "d": ["The selective interaction of actin monomers with specific molecules that inhibit their polymerization by preventing their access to other monomers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097339", "l": "glycolate transmembrane transport", "d": ["The process in which glycolate is transported across a membrane. Glycolate is the anion of hydroxyethanoic acid (glycolic acid)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0031139", "l": "positive regulation of conjugation with cellular fusion", "d": ["Any process that increases the rate or frequency of conjugation with cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050945", "l": "positive regulation of iridophore differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of iridophore differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018291", "l": "molybdenum incorporation into iron-sulfur cluster", "d": ["The incorporation of molybdenum into an iron-sulfur cluster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060264", "l": "regulation of respiratory burst involved in inflammatory response", "d": ["Any process that modulates the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042760", "l": "very long-chain fatty acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a very long chain fatty acid, a fatty acid with an aliphatic tail of 22 or more carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045291", "l": "mRNA trans splicing, SL addition", "d": ["The joining together of two independently transcribed RNAs, where the one that provides the 5' portion of the final mRNA is from a splice leader RNA (SL-RNA). The SL-RNA, or mini-exon donor sequence, is added to the 5'-end of the acceptor RNA molecule which provides the mRNA body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039574", "l": "disruption by virus of host JAK-STAT cascade via inhibition of host TYK2 activity", "d": ["Any process in which a virus interferes with a JAK1-STAT signaling cascade in a host organism by reducing the activity of host TYK2 (tyrosine kinase 2). TYK2 is an intracellular signal-transducing tyrosine kinase that associates with the cytoplasmic tails of cytokine receptors and transmits the cytokine signal by phosphorylating receptor subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905959", "l": "positive regulation of cellular response to alcohol", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033492", "l": "esculetin metabolic process", "d": ["The chemical reactions and pathways involving esculetin, 6,7-dihydroxycoumarin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0031062", "l": "positive regulation of histone methylation", "d": ["Any process that activates or increases the frequency, rate or extent of the covalent addition of methyl groups to histones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031029", "l": "regulation of septation initiation signaling", "d": ["Any process that modulates the frequency, rate or extent of septation initiation signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010305", "l": "leaf vascular tissue pattern formation", "d": ["Vascular tissue pattern formation as it occurs in the leaf of vascular plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071585", "l": "detoxification of cadmium ion", "d": ["Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903699", "l": "tarsal gland development", "d": ["The process whose specific outcome is the progression of a tarsal gland over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006850", "l": "mitochondrial pyruvate transmembrane transport", "d": ["The process in which pyruvate is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044475", "l": "envenomation resulting in negative regulation of high voltage-gated calcium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a high voltage-gated calcium channel in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0021830", "l": "interneuron migration from the subpallium to the cortex", "d": ["The directed movement of interneurons from the subpallium to the cortex during forebrain development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048572", "l": "short-day photoperiodism", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that falls short of a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 hours minus the critical day length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0035188", "l": "hatching", "d": ["The emergence of an immature organism from a protective structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042712", "l": "paternal behavior", "d": ["Male behaviors associated with the care and rearing offspring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032219", "l": "cell wall macromolecule catabolic process involved in cytogamy", "d": ["The chemical reactions and pathways resulting in the breakdown of macromolecules forming part of a cell wall that contribute to cytogamy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052460", "l": "modulation of nutrient release by symbiont", "d": ["Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070396", "l": "lipoteichoic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008586", "l": "imaginal disc-derived wing vein morphogenesis", "d": ["The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.550707717106313", "identifiers": [{"i": "GO:1903706", "l": "regulation of hemopoiesis", "d": ["Any process that modulates the frequency, rate or extent of hemopoiesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0050994", "l": "regulation of lipid catabolic process", "d": ["Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.523848750789256", "identifiers": [{"i": "GO:0043543", "l": "protein acylation", "d": ["The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002748", "l": "antigen processing and presentation initiated by pattern recognition receptor mediated uptake of antigen", "d": ["Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface pattern recognition receptor (PRR)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1904689", "l": "negative regulation of cytoplasmic translational initiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061914", "l": "negative regulation of growth plate cartilage chondrocyte proliferation", "d": ["Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018878", "l": "aerobic beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process", "d": ["The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane that occur in presence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.191563080215587", "identifiers": [{"i": "GO:0120031", "l": "plasma membrane bounded cell projection assembly", "d": ["Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006361", "l": "transcription initiation at RNA polymerase I promoter", "d": ["A transcription initiation process that takes place at a RNA polymerase I gene promoter. Ribosomal RNAs (rRNA) genes are transcribed by RNA polymerase I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071924", "l": "chemokine (C-C motif) ligand 22 production", "d": ["The appearance of chemokine (C-C motif) ligand 22 (CCL22) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0003057", "l": "regulation of the force of heart contraction by chemical signal", "d": ["The regulation of the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090095", "l": "regulation of metanephric cap mesenchymal cell proliferation", "d": ["Any process that modulates the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902863", "l": "regulation of embryonic camera-type eye development", "d": ["Any process that modulates the frequency, rate or extent of embryonic camera-type eye development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048053", "l": "R1/R6 development", "d": ["The process whose specific outcome is the progression of the R1 and R6 pair of photoreceptors in the eye over time, from their formation to the mature structures. R1 and R6 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903571", "l": "negative regulation of protein kinase D signaling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein kinase D signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010117", "l": "photoprotection", "d": ["Protection mechanism used by plants under conditions of excess energy absorption as a consequence of the light reactions of photosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905700", "l": "negative regulation of xenobiotic detoxification by transmembrane export across the plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903093", "l": "regulation of protein K48-linked deubiquitination", "d": ["Any process that modulates the frequency, rate or extent of protein K48-linked deubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0044552", "l": "vasodilation in another organism", "d": ["A process by which an organism causes vasodilation of blood vessels, usually causing a reduction in blood pressure, in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120070", "l": "negative regulation of stomach fundus smooth muscle contraction", "d": ["Any process that decreases the frequency, rate or extent of any stomach fundus smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0016185", "l": "synaptic vesicle budding from presynaptic endocytic zone membrane", "d": ["Evagination of the presynaptic membrane, resulting in the formation of a new synaptic vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905366", "l": "negative regulation of intralumenal vesicle formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intralumenal vesicle formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033087", "l": "negative regulation of immature T cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031581", "l": "hemidesmosome assembly", "d": ["Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030501", "l": "positive regulation of bone mineralization", "d": ["Any process that activates or increases the frequency, rate or extent of bone mineralization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0071963", "l": "establishment or maintenance of cell polarity regulating cell shape", "d": ["Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060908", "l": "plasmid copy number maintenance", "d": ["The maintenance of the number of copies of extrachromosomal plasmid DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990543", "l": "mitochondrial S-adenosyl-L-methionine transmembrane transport", "d": ["The process in which S-adenosyl-L-methionine is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0018874", "l": "benzoate metabolic process", "d": ["The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900889", "l": "positive regulation of pentadecane biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of pentadecane biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072382", "l": "minus-end-directed vesicle transport along microtubule", "d": ["The directed movement of a vesicle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071965", "l": "multicellular organismal locomotion", "d": ["Locomotion in a multicellular organism, i.e. self-propelled movement of a multicellular organism from one location to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.187403162058388", "identifiers": [{"i": "GO:0070254", "l": "mucus secretion", "d": ["The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1905962", "l": "glutamatergic neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a glutamatergic neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006728", "l": "pteridine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039522", "l": "suppression by virus of host mRNA export from nucleus", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of movement of mRNA from the nucleus to the cytoplasm in the host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030919", "l": "peptidyl-serine O-acetylation", "d": ["The acetylation of peptidyl-serine to form peptidyl-O-acetyl-L-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0009448", "l": "gamma-aminobutyric acid metabolic process", "d": ["The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031043", "l": "O-glycan processing, core 7", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 7 O-glycan structure, GalNAc-alpha-(1->6)-GalNAc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.594043123901756", "identifiers": [{"i": "GO:1902850", "l": "microtubule cytoskeleton organization involved in mitosis", "d": ["Any microtubule cytoskeleton organization that is involved in mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0045931", "l": "positive regulation of mitotic cell cycle", "d": ["Any process that activates or increases the rate or extent of progression through the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010835", "l": "regulation of protein ADP-ribosylation", "d": ["Any process that modulates the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071039", "l": "nuclear polyadenylation-dependent CUT catabolic process", "d": ["The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a cryptic unstable transcript (CUT), initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target CUT."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061926", "l": "positive regulation of formation of radial glial scaffolds", "d": ["Any process that increases the frequency, rate or extent of the formation of radial glial cell scaffolds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106025", "l": "positive regulation of pupariation", "d": ["Any process that activates or increases the frequency, rate or extent of onset of pupariation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000838", "l": "negative regulation of androstenedione secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of androstenedione secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006607", "l": "NLS-bearing protein import into nucleus", "d": ["The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus, across the nuclear envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:1901401", "l": "regulation of tetrapyrrole metabolic process", "d": ["Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.161881760686384", "identifiers": [{"i": "GO:0010975", "l": "regulation of neuron projection development", "d": ["Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003083", "l": "negative regulation of renal output by angiotensin", "d": ["The process in which angiotensin directly decreases the rate of natriuresis and diuresis in the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0034408", "l": "ascospore wall beta-glucan metabolic process", "d": ["The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040005", "l": "chitin-based cuticle attachment to epithelium", "d": ["Attaching of a chitin-containing cuticle to the epithelium underlying it. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903288", "l": "positive regulation of potassium ion import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of potassium ion import across the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009089", "l": "lysine biosynthetic process via diaminopimelate", "d": ["The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0006842", "l": "tricarboxylic acid transport", "d": ["The directed movement of tricarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904752", "l": "regulation of vascular associated smooth muscle cell migration", "d": ["Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060049", "l": "regulation of protein glycosylation", "d": ["Any process that modulates the frequency, rate or extent of protein glycosylation. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035071", "l": "salivary gland cell autophagic cell death", "d": ["The stage-specific programmed cell death of salivary gland cells during salivary gland histolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099630", "l": "postsynaptic neurotransmitter receptor cycle", "d": ["The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0014816", "l": "skeletal muscle satellite cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a satellite cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019762", "l": "glucosinolate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0035767", "l": "endothelial cell chemotaxis", "d": ["The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905945", "l": "regulation of response to calcium ion", "d": ["Any process that modulates the frequency, rate or extent of response to calcium ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904620", "l": "cellular response to dimethyl sulfoxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099506", "l": "synaptic vesicle transport along actin filament", "d": ["The directed movement of synaptic vesicles along actin filaments within a cell, powered by molecular motors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009695", "l": "jasmonic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of jasmonic acid, a fatty acid derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075003", "l": "adhesion of symbiont appressorium to host", "d": ["The attachment of an appressorium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0010966", "l": "regulation of phosphate transport", "d": ["Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002467", "l": "germinal center formation", "d": ["The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905412", "l": "negative regulation of mitotic cohesin loading", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin loading."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0032782", "l": "bile acid secretion", "d": ["The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901250", "l": "negative regulation of lung goblet cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lung goblet cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.783030043623796", "identifiers": [{"i": "GO:0043966", "l": "histone H3 acetylation", "d": ["The modification of histone H3 by the addition of an acetyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:1900046", "l": "regulation of hemostasis", "d": ["Any process that modulates the frequency, rate or extent of hemostasis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0042473", "l": "outer ear morphogenesis", "d": ["The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060188", "l": "regulation of protein desumoylation", "d": ["Any process that modulates the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090026", "l": "positive regulation of monocyte chemotaxis", "d": ["Any process that increases the frequency, rate, or extent of monocyte chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061139", "l": "bud field specification", "d": ["The regionalization process in which the identity of a bud primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090221", "l": "mitotic spindle-templated microtubule nucleation", "d": ["The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from within the mitotic spindle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1901977", "l": "negative regulation of cell cycle checkpoint", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle checkpoint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0015816", "l": "glycine transport", "d": ["The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045856", "l": "positive regulation of pole plasm oskar mRNA localization", "d": ["Any process that activates or increases the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0050941", "l": "negative regulation of pigment cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0048708", "l": "astrocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0051615", "l": "histamine uptake", "d": ["The directed movement of histamine into a cell, typically presynaptic neurons or glial cells. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007414", "l": "axonal defasciculation", "d": ["Separation of axons away from a bundle of axons known as a fascicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006934", "l": "substrate-bound cell migration, adhesion receptor recycling", "d": ["The directed movement of accumulated adhesion components such as integrins from the rear of a migrating cell toward the cell front, where they are available to form new protrusions and adhesions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902458", "l": "positive regulation of stomatal opening", "d": ["Any process that activates or increases the frequency, rate or extent of stomatal opening."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003420", "l": "regulation of growth plate cartilage chondrocyte proliferation", "d": ["Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.327400668044291", "identifiers": [{"i": "GO:0008345", "l": "larval locomotory behavior", "d": ["Locomotory behavior in a larval (immature) organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061040", "l": "female gonad morphogenesis", "d": ["The process in which a female gonad is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060234", "l": "neuroblast delamination", "d": ["The negative regulation of cell adhesion process in which a neuroblast splits off of a neurectodermal sheet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045992", "l": "negative regulation of embryonic development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904644", "l": "cellular response to curcumin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021586", "l": "pons maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904502", "l": "regulation of lipophagy", "d": ["Any process that modulates the frequency, rate or extent of lipophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904459", "l": "negative regulation of substance P secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001895", "l": "retina homeostasis", "d": ["A tissue homeostatic process involved in the maintenance of an internal equilibrium within the retina of the eye, including control of cellular proliferation and death and control of metabolic function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007546", "l": "somatic processes downstream of sex determination signal", "d": ["The events determining the somatic sexual phenotype after the initial transmission of that phenotype to soma-specific information pathways."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031318", "l": "detection of folic acid", "d": ["The series of events in which a folic acid stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033321", "l": "homomethionine metabolic process", "d": ["The chemical reactions and pathways involving homomethionine, a non-protein amino acid synthesized from methionine via chain elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0014013", "l": "regulation of gliogenesis", "d": ["Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019532", "l": "oxalate transport", "d": ["The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097706", "l": "vascular endothelial cell response to oscillatory fluid shear stress", "d": ["Any response to oscillatory fluid shear stress that occurs in a vascular endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090001", "l": "replication fork arrest at tRNA locus", "d": ["A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic tRNA transcription unit."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006294", "l": "nucleotide-excision repair, preincision complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins on DNA to form the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. This assembly occurs before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021674", "l": "rhombomere 8 morphogenesis", "d": ["The process in which the anatomical structure of rhombomere 8 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021581", "l": "medulla oblongata structural organization", "d": ["The process that contributes to the act of creating the structural organization of the medulla oblongata. This process pertains to the physical shaping of a rudimentary structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032012", "l": "regulation of ARF protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of ARF protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030649", "l": "aminoglycoside antibiotic catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904480", "l": "positive regulation of intestinal absorption", "d": ["Any process that activates or increases the frequency, rate or extent of intestinal absorption."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0038055", "l": "BMP secretion", "d": ["The controlled release of a member of the BMP family of proteins from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0099191", "l": "trans-synaptic signaling by BDNF", "d": ["Cell-cell signaling between presynapse and postsynapse mediated by brain-derived neurotrophic factor (BDNF) crossing the synaptic cleft."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060162", "l": "negative regulation of phospholipase C-activating dopamine receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the dopamine receptor, phospholipase C activating pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.260205192077891", "identifiers": [{"i": "GO:0019438", "l": "aromatic compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035899", "l": "negative regulation of blood coagulation in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.694848273704821", "identifiers": [{"i": "GO:0001958", "l": "endochondral ossification", "d": ["Replacement ossification wherein bone tissue replaces cartilage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0021534", "l": "cell proliferation in hindbrain", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001114", "l": "positive regulation of cellular response to hepatocyte growth factor stimulus", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.509227218911647", "identifiers": [{"i": "GO:0042278", "l": "purine nucleoside metabolic process", "d": ["The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032464", "l": "positive regulation of protein homooligomerization", "d": ["Any process that activates or increases the frequency, rate or extent of protein homooligomerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006309", "l": "apoptotic DNA fragmentation", "d": ["The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0006527", "l": "arginine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035742", "l": "activated CD8-positive, alpha-beta T cell proliferation", "d": ["The expansion of an activated CD8-positive, alpha-beta T cell population by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0000082", "l": "G1/S transition of mitotic cell cycle", "d": ["The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1905957", "l": "regulation of cellular response to alcohol", "d": ["Any process that modulates the frequency, rate or extent of cellular response to alcohol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0006662", "l": "glycerol ether metabolic process", "d": ["The chemical reactions and pathways involving glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044644", "l": "envenomation resulting in negative regulation of complement activation, alternative pathway in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the alternative pathway in the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060408", "l": "regulation of acetylcholine metabolic process", "d": ["Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0006606", "l": "protein import into nucleus", "d": ["The directed movement of a protein from the cytoplasm to the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097103", "l": "endothelial stalk cell fate specification", "d": ["The process involved in the specification of identity of an endothelial stalk cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial stalk cell is a specialized endothelial cell which follows behind the tip cell of an angiogenic sprout."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.738263026760649", "identifiers": [{"i": "GO:0002437", "l": "inflammatory response to antigenic stimulus", "d": ["An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015954", "l": "pyrimidine ribonucleotide interconversion", "d": ["The chemical reactions and pathways by which a pyrimidine ribonucleotide is synthesized from another pyrimidine ribonucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018972", "l": "toluene-4-sulfonate metabolic process", "d": ["The chemical reactions and pathways involving toluene-4-sulfonate, the anion of 4-toluene sulfonic acid, a white crystalline solid which is highly hygroscopic and soluble in water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097436", "l": "entry into dormancy", "d": ["The dormancy process that results in entry into dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090252", "l": "epithelium migration involved in imaginal disc-derived wing morphogenesis", "d": ["The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001286", "l": "regulation of caveolin-mediated endocytosis", "d": ["Any process that modulates the frequency, rate or extent of caveolin-mediated endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1990170", "l": "stress response to cadmium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a cadmium ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0001759", "l": "organ induction", "d": ["The interaction of two or more cells or tissues that causes them to change their fates and specify the development of an organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120306", "l": "cellular response to actin cytoskeletal stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of perturbations or damage to the actin cytoskeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070285", "l": "pigment cell development", "d": ["The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072754", "l": "cellular response to purvalanol A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120223", "l": "larynx morphogenesis", "d": ["The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.738263026760649", "identifiers": [{"i": "GO:0022404", "l": "molting cycle process", "d": ["A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021896", "l": "forebrain astrocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0120263", "l": "positive regulation of heterochromatin organization", "d": ["Any process that activates or increases the frequency, rate or extent of heterochromatin organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902165", "l": "regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "d": ["Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.157169620444122", "identifiers": [{"i": "GO:0046165", "l": "alcohol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.542815643789396", "identifiers": [{"i": "GO:0009583", "l": "detection of light stimulus", "d": ["The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0033865", "l": "nucleoside bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043613", "l": "isoprene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of isoprene, C5H8."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.357413409522593", "identifiers": [{"i": "GO:0071496", "l": "cellular response to external stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000292", "l": "RNA fragment catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061120", "l": "regulation of positive chemotaxis to cAMP by DIF-1", "d": ["Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032227", "l": "negative regulation of synaptic transmission, dopaminergic", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061551", "l": "trigeminal ganglion development", "d": ["The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900188", "l": "negative regulation of cell adhesion involved in single-species biofilm formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in single-species biofilm formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071654", "l": "positive regulation of chemokine (C-C motif) ligand 1 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900575", "l": "emodin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of emodin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051795", "l": "positive regulation of timing of catagen", "d": ["Any process that activates or increases the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006933", "l": "negative regulation of cell adhesion involved in substrate-bound cell migration", "d": ["The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.905555711669919", "identifiers": [{"i": "GO:0032602", "l": "chemokine production", "d": ["The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900320", "l": "positive regulation of methane biosynthetic process from dimethylamine", "d": ["Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0106354", "l": "tRNA surveillance", "d": ["The set of processes involved in identifying and degrading defective or aberrant tRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048934", "l": "peripheral nervous system neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014860", "l": "neurotransmitter secretion involved in regulation of skeletal muscle contraction", "d": ["The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905583", "l": "cellular response to mannose", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009211", "l": "pyrimidine deoxyribonucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900826", "l": "negative regulation of membrane depolarization during cardiac muscle cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903615", "l": "positive regulation of protein tyrosine phosphatase activity", "d": ["Any process that activates or increases the frequency, rate or extent of protein tyrosine phosphatase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0045105", "l": "intermediate filament polymerization or depolymerization", "d": ["Assembly or disassembly of intermediate filaments by the addition or removal of component parts from a filament."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010567", "l": "regulation of ketone catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:2000001", "l": "regulation of DNA damage checkpoint", "d": ["Any process that modulates the frequency, rate or extent of a DNA damage checkpoint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0045827", "l": "negative regulation of isoprenoid metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900039", "l": "positive regulation of cellular response to hypoxia", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to hypoxia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090035", "l": "positive regulation of chaperone-mediated protein complex assembly", "d": ["Any process that increases the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032363", "l": "FMN catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901844", "l": "regulation of cell communication by electrical coupling involved in cardiac conduction", "d": ["Any process that modulates the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905702", "l": "regulation of inhibitory synapse assembly", "d": ["Any process that modulates the frequency, rate or extent of inhibitory synapse assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0030835", "l": "negative regulation of actin filament depolymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of actin depolymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007508", "l": "larval heart development", "d": ["The process whose specific outcome is the progression of the larval heart over time, from its formation to the mature structure. In Drosophila the larval heart (dorsal vessel) is a continuous tube of mesodormal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060307", "l": "regulation of ventricular cardiac muscle cell membrane repolarization", "d": ["Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0032509", "l": "endosome transport via multivesicular body sorting pathway", "d": ["The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060274", "l": "maintenance of stationary phase", "d": ["The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction. Stationary phase can be in response to limited nutrients or a build-up of toxic substances in the environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032932", "l": "negative regulation of astral microtubule depolymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of astral microtubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904439", "l": "negative regulation of iron ion import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of iron ions import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900861", "l": "regulation of cordyol C biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of cordyol C biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0050958", "l": "magnetoreception", "d": ["The series of events required for an organism to receive a stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Stimuli may be chemical, mechanical or electrical and interpreting these stimuli allows an organism to determine the orientation of a magnetic field. Magnetoreception also involves the perception of light; birds cannot orient without the presence of short wavelength (blue/green) light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033531", "l": "stachyose metabolic process", "d": ["The chemical reactions and pathways involving stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046678", "l": "response to bacteriocin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080162", "l": "endoplasmic reticulum to cytosol auxin transport", "d": ["The directed movement of auxins from endoplasmic reticulum to cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0001835", "l": "blastocyst hatching", "d": ["The hatching of the cellular blastocyst from the zona pellucida."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905098", "l": "negative regulation of guanyl-nucleotide exchange factor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of guanyl-nucleotide exchange factor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035641", "l": "locomotory exploration behavior", "d": ["The specific movement from place to place of an organism in response to a novel environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0016057", "l": "regulation of membrane potential in photoreceptor cell", "d": ["Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900148", "l": "negative regulation of Schwann cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0034285", "l": "response to disaccharide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072386", "l": "plus-end-directed organelle transport along microtubule", "d": ["The directed movement of an organelle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032960", "l": "regulation of inositol trisphosphate biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032759", "l": "positive regulation of TRAIL production", "d": ["Any process that activates or increases the frequency, rate, or extent of TRAIL production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901902", "l": "tyrocidine metabolic process", "d": ["The chemical reactions and pathways involving tyrocidine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0070296", "l": "sarcoplasmic reticulum calcium ion transport", "d": ["The directed movement of calcium ions (Ca2+) into, out of or within the sarcoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002618", "l": "positive regulation of macrophage antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0017062", "l": "respiratory chain complex III assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex, a transmembrane lipoprotein complex that it catalyzes the reduction of cytochrome c by accepting reducing equivalents from Coenzyme Q, by the aggregation, arrangement and bonding together of its constituents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080020", "l": "regulation of coenzyme A biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzyme A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045640", "l": "regulation of basophil differentiation", "d": ["Any process that modulates the frequency, rate or extent of basophil differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0080186", "l": "developmental vegetative growth", "d": ["The increase in size or mass of non-reproductive plant parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905835", "l": "cellular response to pyrimidine ribonucleotide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0010955", "l": "negative regulation of protein processing", "d": ["Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044621", "l": "modulation of cell migration in another organism", "d": ["The process in which an organism effects a change in the process of cell migration in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010091", "l": "trichome branching", "d": ["Any process involved in the formation of branches in plant hair cells. An example of this process is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0034694", "l": "response to prostaglandin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901189", "l": "positive regulation of ephrin receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of ephrin receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045603", "l": "positive regulation of endothelial cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0042472", "l": "inner ear morphogenesis", "d": ["The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900396", "l": "positive regulation of kojic acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of kojic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019590", "l": "L-arabitol catabolic process to xylulose 5-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-arabitol to form xylulose 5-phosphate. L-arabitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021836", "l": "chemorepulsion involved in postnatal olfactory bulb interneuron migration", "d": ["The creation and reception of signals that repel olfactory bulb interneurons from the subventricular zone as a component process in tangential migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001831", "l": "trophectodermal cellular morphogenesis", "d": ["The morphogenesis of trophectoderm cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097292", "l": "XMP metabolic process", "d": ["The chemical reactions and pathways involving XMP, xanthosine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.192826706633682", "identifiers": [{"i": "GO:0050911", "l": "detection of chemical stimulus involved in sensory perception of smell", "d": ["The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:1905820", "l": "positive regulation of chromosome separation", "d": ["Any process that activates or increases the frequency, rate or extent of chromosome separation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0051931", "l": "regulation of sensory perception", "d": ["Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021940", "l": "positive regulation of cerebellar granule cell precursor proliferation", "d": ["The process that activates or increases the rate or extent of granule cell precursor proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0034105", "l": "positive regulation of tissue remodeling", "d": ["Any process that activates or increases the frequency, rate, or extent of tissue remodeling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.391164428010192", "identifiers": [{"i": "GO:0061025", "l": "membrane fusion", "d": ["The membrane organization process that joins two lipid bilayers to form a single membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904967", "l": "regulation of monopolar spindle attachment to meiosis I kinetochore", "d": ["Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021832", "l": "cell-cell adhesion involved in cerebral cortex tangential migration using cell-cell interactions", "d": ["The attachment of cells to one another to form groups of cells involved in cerebral cortex tangential migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032825", "l": "positive regulation of natural killer cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0006783", "l": "heme biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000003", "l": "positive regulation of DNA damage checkpoint", "d": ["Any process that activates or increases the frequency, rate or extent of a DNA damage checkpoint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:1900424", "l": "regulation of defense response to bacterium", "d": ["Any process that modulates the frequency, rate or extent of defense response to bacterium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050855", "l": "regulation of B cell receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061796", "l": "membrane addition at site of mitotic cytokinesis", "d": ["A mitotic cell cycle process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045721", "l": "negative regulation of gluconeogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075511", "l": "macropinosome lysis involved in viral entry into host cell", "d": ["Viral-induced lysis of the macropinosome involved in the uptake of a virus into a host cell. Occurs after internalization of the virus in a macropinosome, and results in the release of viral contents from the macropinosome into the host cell cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905101", "l": "negative regulation of apoptosome assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptosome assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0097242", "l": "amyloid-beta clearance", "d": ["The process in which amyloid-beta is removed from extracellular brain regions by mechanisms involving cell surface receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019621", "l": "creatinine catabolic process to formate", "d": ["The chemical reactions and pathways resulting in the breakdown of creatinine into other compounds, including formate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044831", "l": "modulation by virus of host cytokine production", "d": ["Any process in which a virus modulates the frequency, rate or extent of cytokine production in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051681", "l": "6-alpha-maltosylglucose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 6-alpha-maltosylglucose, also known as isopanose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006257", "l": "dUDP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dUDP, deoxyuridine (5'-)diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0032948", "l": "regulation of alpha-glucan metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-glucans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0039013", "l": "pronephric distal tubule morphogenesis", "d": ["The process in which the anatomical structures of a pronephric nephron distal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000388", "l": "spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)", "d": ["Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099641", "l": "anterograde axonal protein transport", "d": ["The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0033299", "l": "secretion of lysosomal enzymes", "d": ["The controlled release of lysosomal enzymes by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0000911", "l": "cytokinesis by cell plate formation", "d": ["The process of dividing the cytoplasm of a parent cell where a structure forms in the cytoplasm and grows until reaching the plasma membrane, thereby completely separating the cytoplasms of adjacent progeny cells. An example of this is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904590", "l": "negative regulation of protein import", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein import."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080035", "l": "2-hydroxy-but-3-enyl glucosinolate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of progoitrin, a 2-hydroxy-but-3-enyl glucosinolate. Glucosinolates are substituted thioglucosides found in rapeseed products and related cruciferae, and progoitrin has been implicated in causing goiters in mammals and bitter taste in cruciferous vegetables."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045616", "l": "regulation of keratinocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of keratinocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003160", "l": "endocardium morphogenesis", "d": ["The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021797", "l": "forebrain anterior/posterior pattern specification", "d": ["The creation of specific areas of progenitor domains along the anterior-posterior axis of the developing forebrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905488", "l": "positive regulation of anterior/posterior axon guidance", "d": ["Any process that activates or increases the frequency, rate or extent of anterior/posterior axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000692", "l": "negative regulation of seed maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of seed maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0015793", "l": "glycerol transmembrane transport", "d": ["The directed movement of glycerol across a membrane. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904837", "l": "beta-catenin-TCF complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905633", "l": "establishment of protein localization to euchromatin", "d": ["The directed movement of a protein to a specific location in an euchromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035853", "l": "chromosome passenger complex localization to spindle midzone", "d": ["A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the spindle midzone. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080065", "l": "4-alpha-methyl-delta7-sterol oxidation", "d": ["A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4-alpha-methyl-delta7-sterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy,delta7-sterol + 3 NADP+ + 3 H2O."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0042365", "l": "water-soluble vitamin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061470", "l": "T follicular helper cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048288", "l": "nuclear membrane fusion involved in karyogamy", "d": ["The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905801", "l": "positive regulation of intraciliary retrograde transport", "d": ["Any process that activates or increases the frequency, rate or extent of intraciliary retrograde transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072023", "l": "thick ascending limb development", "d": ["The process whose specific outcome is the progression of the thick ascending limb over time, from its formation to the mature structure. The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019500", "l": "cyanide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904703", "l": "negative regulation of protein localization to adherens junction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.154928939654667", "identifiers": [{"i": "GO:0008217", "l": "regulation of blood pressure", "d": ["Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0099024", "l": "plasma membrane invagination", "d": ["An infolding of the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044053", "l": "translocation of peptides or proteins into host cell cytoplasm", "d": ["The directed movement of peptides or proteins produced by a symbiont organism to a location within the host cell cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000527", "l": "regulation of myeloid dendritic cell chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of myeloid dendritic cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901706", "l": "mesenchymal cell differentiation involved in bone development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "43.485382913873444", "identifiers": [{"i": "GO:0016043", "l": "cellular component organization", "d": ["A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071288", "l": "cellular response to mercury ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021641", "l": "trochlear nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the trochlear nerve. This process pertains to the physical shaping of a rudimentary structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903383", "l": "regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140887", "l": "positive regulation of nucleosome disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of the controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904418", "l": "regulation of telomeric loop formation", "d": ["Any process that modulates the frequency, rate or extent of telomeric loop formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.651716354923636", "identifiers": [{"i": "GO:0009311", "l": "oligosaccharide metabolic process", "d": ["The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0060600", "l": "dichotomous subdivision of an epithelial terminal unit", "d": ["The process in which an epithelial cord, rod or tube bifurcates at its end."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048829", "l": "root cap development", "d": ["The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048460", "l": "flower formation", "d": ["The process that gives rise to the flower. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043377", "l": "negative regulation of CD8-positive, alpha-beta T cell differentiation", "d": ["Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071681", "l": "cellular response to indole-3-methanol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043653", "l": "mitochondrial fragmentation involved in apoptotic process", "d": ["The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0010039", "l": "response to iron ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033387", "l": "putrescine biosynthetic process from ornithine", "d": ["The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane by decarboxylation of ornithine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002518", "l": "lymphocyte chemotaxis across high endothelial venule", "d": ["The movement of a lymphocyte to cross a high endothelial venule in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903254", "l": "hercynylselenocysteine metabolic process", "d": ["The chemical reactions and pathways involving hercynylselenocysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002582", "l": "positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II", "d": ["Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1903716", "l": "guanine transmembrane transport", "d": ["The process in which guanine is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903197", "l": "positive regulation of L-dopa biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of L-dopa biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904869", "l": "regulation of protein localization to Cajal body", "d": ["Any process that modulates the frequency, rate or extent of protein localization to Cajal body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900386", "l": "positive regulation of flavonol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of flavonol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990678", "l": "histone H4-K16 deacetylation", "d": ["The modification of histone H4 by the removal of an acetyl group from lysine at position 16 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0043461", "l": "proton-transporting ATP synthase complex assembly", "d": ["The aggregation, arrangement and bonding together of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000088", "l": "mitotic prophase", "d": ["The cell cycle phase which is the first stage of M phase of mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150129", "l": "positive regulation of interleukin-33 production", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-33 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.362525179576039", "identifiers": [{"i": "GO:0044837", "l": "actomyosin contractile ring organization", "d": ["A process which results in the assembly, arrangement of constituent parts, or disassembly of an actomyosin contractile ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035054", "l": "embryonic heart tube anterior/posterior pattern specification", "d": ["The establishment, maintenance and elaboration of cell differentiation that results in the anterior/posterior subdivision of the embryonic heart tube. In Drosophila this results in subdivision of the dorsal vessel into to the posterior heart proper and the anterior aorta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006209", "l": "cytosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:1905133", "l": "negative regulation of meiotic chromosome separation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of meiotic chromosome separation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905453", "l": "regulation of myeloid progenitor cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.161881760686384", "identifiers": [{"i": "GO:0050807", "l": "regulation of synapse organization", "d": ["Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048303", "l": "negative regulation of isotype switching to IgG isotypes", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgG isotypes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031283", "l": "negative regulation of guanylate cyclase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of guanylate cyclase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048359", "l": "mucilage metabolic process involved in seed coat development", "d": ["The chemical reactions and pathways involving mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000601", "l": "positive regulation of Arp2/3 complex-mediated actin nucleation", "d": ["Any process that activates or increases the frequency, rate or extent of Arp2/3 complex-mediated actin nucleation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000084", "l": "regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904381", "l": "Golgi apparatus mannose trimming", "d": ["Any protein alpha-1,2-demannosylation that takes place in the Golgi apparatus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019540", "l": "catechol-containing siderophore biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including catechol. Catechol is one of the three major chemical groups incorporated into siderophore structures with hydroxamate and a-hydroxycarboxylate, each having a high selectivity for iron(3+)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043637", "l": "puromycin metabolic process", "d": ["The chemical reactions and pathways involving puromycin, 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051363", "l": "peptidoglycan-protein cross-linking via L-alanyl-pentaglycyl-murein", "d": ["The process of linking a protein to peptidoglycan via a carboxy terminal alanine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.216228972255621", "identifiers": [{"i": "GO:1903530", "l": "regulation of secretion by cell", "d": ["Any process that modulates the frequency, rate or extent of secretion by cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1903778", "l": "protein localization to vacuolar membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0051322", "l": "anaphase", "d": ["The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.058137015083851", "identifiers": [{"i": "GO:0007018", "l": "microtubule-based movement", "d": ["A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034116", "l": "positive regulation of heterotypic cell-cell adhesion", "d": ["Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061284", "l": "specification of mesonephric proximal tubule identity", "d": ["The process in which the proximal tubule of the mesonephric nephron acquires its identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034514", "l": "mitochondrial unfolded protein response", "d": ["The series of molecular signals generated as a consequence of the presence of unfolded proteins in the mitochondrial matrix; results in transcriptional upregulation of nuclear genes encoding mitochondrial stress proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.780700721499244", "identifiers": [{"i": "GO:0042640", "l": "anagen", "d": ["The growth phase of the hair cycle. Lasts, for example, about 3 to 6 years for human scalp hair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904812", "l": "rRNA acetylation involved in maturation of SSU-rRNA", "d": ["Any rRNA acetylation that is involved in maturation of SSU-rRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0034394", "l": "protein localization to cell surface", "d": ["A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019664", "l": "mixed acid fermentation", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into ethanol, lactate, formate, succinate, and acetate, yielding energy in the form of ATP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140026", "l": "contractile vacuole dissociation from plasma membrane", "d": ["The dissociation of the contractile vacuole after discharge, from the plasma membrane. This interaction is mediated by detethering factors that initiate the process of tubulation and fragmentation of the empty contractile vacuole bladder, which is then reincorporated into the CV network."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000338", "l": "protein deneddylation", "d": ["The removal of a ubiquitin-like protein of the NEDD8 type from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045214", "l": "sarcomere organization", "d": ["The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000808", "l": "negative regulation of synaptic vesicle clustering", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle clustering."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900980", "l": "regulation of phenazine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of phenazine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0015801", "l": "aromatic amino acid transport", "d": ["The directed movement of aromatic amino acids, amino acids with aromatic ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.338826399587582", "identifiers": [{"i": "GO:0045935", "l": "positive regulation of nucleobase-containing compound metabolic process", "d": ["Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003204", "l": "cardiac skeleton development", "d": ["The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0010812", "l": "negative regulation of cell-substrate adhesion", "d": ["Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070668", "l": "positive regulation of mast cell proliferation", "d": ["Any process that activates or increases the rate or extent of mast cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060965", "l": "negative regulation of miRNA-mediated gene silencing", "d": ["A process that decreases the rate, frequency, or extent of gene silencing by a microRNA (miRNA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990747", "l": "pancreatic trypsinogen secretion", "d": ["The regulated release of trypsinogen from the cells of the exocrine pancreas."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000055", "l": "positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification", "d": ["Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035077", "l": "ecdysone-mediated polytene chromosome puffing", "d": ["The decondensing (loosening) and swelling of the chromosomal sites of hormone-responsive genes on polytene chromosomes in response to increased production of the steroid hormone 20-hydroxyecdysone (ecdysone) in Drosophila larvae approaching pupation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903750", "l": "regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "d": ["Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000237", "l": "positive regulation of tRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of tRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046521", "l": "sphingoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030644", "l": "intracellular chloride ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of chloride ions within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902831", "l": "positive regulation of spinal cord association neuron differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of spinal cord association neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.23035275591424", "identifiers": [{"i": "GO:0044058", "l": "regulation of digestive system process", "d": ["Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070550", "l": "rDNA chromatin condensation", "d": ["The process in which the chromatin structure of the rDNA repeats is compacted. In S. cerevisiae, condensation and resolution of the rDNA occurs during anaphase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0032872", "l": "regulation of stress-activated MAPK cascade", "d": ["Any process that modulates the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032826", "l": "regulation of natural killer cell differentiation involved in immune response", "d": ["Any process that modulates the frequency, rate or extent of natural killer cell differentiation as part of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070779", "l": "D-aspartate import across plasma membrane", "d": ["The directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120041", "l": "positive regulation of macrophage proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900292", "l": "negative regulation of galactotriose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of galactotriose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042457", "l": "ethylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009741", "l": "response to brassinosteroid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900438", "l": "negative regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903190", "l": "glyoxal catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glyoxal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072747", "l": "cellular response to chloramphenicol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902162", "l": "regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "d": ["Any process that modulates the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120058", "l": "positive regulation of small intestinal transit", "d": ["Any process that increases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044528", "l": "regulation of mitochondrial mRNA stability", "d": ["Any process that modulates the propensity of mitochondrial mRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial mRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050940", "l": "regulation of late stripe melanocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of late stripe melanocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904614", "l": "response to biphenyl", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "55.515254128047744", "identifiers": [{"i": "GO:0006091", "l": "generation of precursor metabolites and energy", "d": ["The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905528", "l": "positive regulation of Golgi lumen acidification", "d": ["Any process that activates or increases the frequency, rate or extent of Golgi lumen acidification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014846", "l": "esophagus smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the esophagus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The esophagus is the muscular membranous segment between the pharynx and the stomach in the upper gastrointestinal tract."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0036230", "l": "granulocyte activation", "d": ["The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033385", "l": "geranylgeranyl diphosphate metabolic process", "d": ["The chemical reactions and pathways involving geranylgeranyl diphosphate, a polyprenol compound involved in the biosynthesis of a variety of terpenoids including chlorophylls, carotenoids, tocopherols, plastoquinones, and the plant hormones gibberellins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019284", "l": "L-methionine salvage from S-adenosylmethionine", "d": ["The chemical reactions and pathways resulting in the formation of L-methionine from S-adenosylmethionine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:1902441", "l": "protein localization to meiotic spindle pole body", "d": ["A process in which a protein is transported to, or maintained in, a location within a meiotic spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019247", "l": "lactate racemization", "d": ["Partial conversion of one lactate enantiomer into another so that the specific optical rotation is decreased, or even reduced to zero, in the resulting mixture."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903806", "l": "L-isoleucine import across plasma membrane", "d": ["The directed movement of L-isoleucine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000173", "l": "negative regulation of branching morphogenesis of a nerve", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.958453806446542", "identifiers": [{"i": "GO:0007617", "l": "mating behavior", "d": ["The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0006678", "l": "glucosylceramide metabolic process", "d": ["The chemical reactions and pathways involving glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. They are neutral glycolipids containing equimolar amounts of fatty acid, glucose, and sphingosine or a sphingosine derivative."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0071248", "l": "cellular response to metal ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003295", "l": "cell proliferation involved in atrial ventricular junction remodeling", "d": ["The multiplication or reproduction of cells that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140648", "l": "positive regulation of cell cycle switching, mitotic to meiotic cell cycle", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0031126", "l": "sno(s)RNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a snoRNA family molecule, also referred to as an sRNA in Archaea."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903982", "l": "negative regulation of microvillus length", "d": ["A process that decreases the length of a microvillus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010479", "l": "stele development", "d": ["The process whose specific outcome is the progression of the stele over time, from its formation to the mature structure. The stele is the central column of primary vascular tissue in the root and any tissue that it surrounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070637", "l": "pyridine nucleoside metabolic process", "d": ["The chemical reactions and pathways involving any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0001868", "l": "regulation of complement activation, lectin pathway", "d": ["Any process that modulates the frequency, rate or extent of the lectin pathway of complement activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070658", "l": "neuromast hair cell differentiation involved in neuromast regeneration", "d": ["Differentiation of new neuromast sensory hair cells to replace those lost or destroyed by injury."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097328", "l": "response to carboplatin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carboplatin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002265", "l": "astrocyte activation involved in immune response", "d": ["A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036023", "l": "embryonic skeletal limb joint morphogenesis", "d": ["The process, occurring in the embryo, in which the anatomical structures of a skeletal limb joint are generated and organized. A skeletal limb joint is the connecting structure between the bones of a limb."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0043628", "l": "regulatory ncRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a regulatory non-coding RNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075299", "l": "positive regulation of zygospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019555", "l": "glutamate catabolic process to ornithine", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including ornithine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097385", "l": "programmed necrotic cell death in response to starvation", "d": ["A programmed necrotic cell death occurring as a result of a starvation stimulus (deprivation of nourishment)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044341", "l": "sodium-dependent phosphate transport", "d": ["The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, by a mechanism dependent upon sodium ions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046167", "l": "glycerol-3-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycerol-3-phosphate, a phosphoric monoester of glycerol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905804", "l": "positive regulation of cellular response to manganese ion", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to manganese ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098598", "l": "learned vocalization behavior or vocal learning", "d": ["Vocalisation behavior that is the result of learning, or the process by which new vocalizations are learned."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106273", "l": "cytosol to ERGIC protein transport", "d": ["The directed movement of proteins from the cystosol to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901188", "l": "negative regulation of ephrin receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ephrin receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:1901983", "l": "regulation of protein acetylation", "d": ["Any process that modulates the frequency, rate or extent of protein acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.503963827996756", "identifiers": [{"i": "GO:0031023", "l": "microtubule organizing center organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007026", "l": "negative regulation of microtubule depolymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010225", "l": "response to UV-C", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019920", "l": "peptidyl-1-thioglycine biosynthetic process, internal", "d": ["The chemical reactions and pathways resulting in the formation of internal peptidyl-1-thioglycine, which has an internal C=S bond, instead of an internal C=O bond, in the peptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034499", "l": "late endosome to Golgi transport", "d": ["The directed movement of substances from late endosomes to the Golgi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097702", "l": "response to oscillatory fluid shear stress", "d": ["Any response to fluid shear stress where the fluid is moving across a solid surface with an oscillatory flow. Disturbed flow patterns at the arterial bifurcations and curvatures may cause endothelial dysfunction, which initiates atherosclerosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0150173", "l": "positive regulation of phosphatidylcholine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylcholine metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905838", "l": "regulation of telomeric D-loop disassembly", "d": ["Any process that modulates the frequency, rate or extent of telomeric D-loop disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900372", "l": "negative regulation of purine nucleotide biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052036", "l": "suppression by symbiont of host inflammatory response", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990418", "l": "response to insulin-like growth factor stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090258", "l": "negative regulation of mitochondrial fission", "d": ["Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902561", "l": "origin recognition complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an origin recognition complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014739", "l": "positive regulation of muscle hyperplasia", "d": ["Any process that activates or increases the frequency, rate or extent of muscle hyperplasia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0106074", "l": "aminoacyl-tRNA metabolism involved in translational fidelity", "d": ["Any process which detects an amino-acid acetylated tRNA is charged with the correct amino acid, or removes incorrect amino acids from a charged tRNA. This process can be performed by tRNA synthases, or by subsequent reactions after tRNA aminoacylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0000270", "l": "peptidoglycan metabolic process", "d": ["The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000187", "l": "positive regulation of phosphate transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018925", "l": "m-cresol metabolic process", "d": ["The chemical reactions and pathways involving m-cresol (3-hydroxytoluene), the meta-isoform of cresol. Used to produce agricultural chemicals, and in specialty resins, pharmaceuticals and pressure-sensitive dyes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046705", "l": "CDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CDP, cytidine (5'-)diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:1902106", "l": "negative regulation of leukocyte differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.06379513530257", "identifiers": [{"i": "GO:0002643", "l": "regulation of tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002110", "l": "cotranscriptional mitochondrial rRNA nucleotide insertion", "d": ["The insertion of one or two non-coded nucleotides during the transcription of a mitochondrial rRNA. Such additions are known to occur in myxomycetes such as Physarum, Didymium, and Stemonitis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0010384", "l": "cell wall proteoglycan metabolic process", "d": ["The chemical reactions and pathways involving cell wall peptidoglycan, a group of glycoproteins that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000477", "l": "generation of mature 5'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Cleavage within ITS2 to generate the mature 5'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010150", "l": "leaf senescence", "d": ["The last stage of leaf development during which programmed degradation of macromolecules and nutrient recycling take place."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021612", "l": "facial nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the facial nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032013", "l": "negative regulation of ARF protein signal transduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ARF protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072717", "l": "cellular response to actinomycin D", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034192", "l": "D-galactonate metabolic process", "d": ["The chemical reactions and pathways involving D-galactonate, the anion of D-galactonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110013", "l": "positive regulation of aggregation involved in sorocarp development", "d": ["Any process that increases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048659", "l": "smooth muscle cell proliferation", "d": ["The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032308", "l": "positive regulation of prostaglandin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0071479", "l": "cellular response to ionizing radiation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045477", "l": "regulation of nurse cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of nurse cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090328", "l": "regulation of olfactory learning", "d": ["Any process that modulates the rate, frequency, or extent of olfactory learning. Olfactory learning is any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901108", "l": "granaticin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of granaticin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051143", "l": "propanediol metabolic process", "d": ["The chemical reactions and pathways involving propanediol, CH3-CHOH-CH2OH, a sweet, colorless, viscous, hygroscopic liquid used as an antifreeze, in brake fluid and as a humectant in cosmetics and personal care items."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007172", "l": "signal complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090365", "l": "regulation of mRNA modification", "d": ["Any process that modulates the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071359", "l": "cellular response to dsRNA", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904849", "l": "positive regulation of cell chemotaxis to fibroblast growth factor", "d": ["Any process that activates or increases the frequency, rate or extent of cell chemotaxis to fibroblast growth factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0000321", "l": "re-entry into mitotic cell cycle after pheromone arrest", "d": ["The resumption of the mitotic cell division cycle by pheromone-arrested cells that have not mated. An example of this process is found in Saccharomyces cerevisiae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.592736662327894", "identifiers": [{"i": "GO:0071310", "l": "cellular response to organic substance", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042479", "l": "positive regulation of eye photoreceptor cell development", "d": ["Any process that activates or increases the frequency, rate or extent of eye photoreceptor development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045150", "l": "acetoin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acetoin, 3-hydroxy-2-butanone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033378", "l": "establishment of protease localization to T cell secretory granule", "d": ["The directed movement of a protease to a location within a secretory granule in a T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000369", "l": "regulation of clathrin-dependent endocytosis", "d": ["Any process that modulates the frequency, rate or extent of clathrin-mediated endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903762", "l": "positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization", "d": ["Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070479", "l": "nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay", "d": ["The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904924", "l": "negative regulation of mitophagy in response to mitochondrial depolarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy in response to mitochondrial depolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071732", "l": "cellular response to nitric oxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900998", "l": "nitrobenzene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nitrobenzene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018133", "l": "peptide cross-linking via L-cysteine oxazolinecarboxylic acid", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002477", "l": "antigen processing and presentation of exogenous peptide antigen via MHC class Ib", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0055010", "l": "ventricular cardiac muscle tissue morphogenesis", "d": ["The process in which the anatomical structures of cardiac ventricle muscle is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002184", "l": "cytoplasmic translational termination", "d": ["The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0099606", "l": "microtubule plus-end directed mitotic chromosome migration", "d": ["The cell cycle process in which chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. This process is part of mitotic metaphase plate congression."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001713", "l": "ectodermal cell fate determination", "d": ["The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an ectoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032909", "l": "regulation of transforming growth factor beta2 production", "d": ["Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015817", "l": "histidine transport", "d": ["The directed movement of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018413", "l": "peptidyl-serine O-glucuronidation", "d": ["The O-glucuronidation of peptidyl-serine to form peptidyl-O3-D-glucuronyl-L-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0010586", "l": "miRNA metabolic process", "d": ["The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019657", "l": "glycolytic fermentation to propionate", "d": ["Glycolytic fermentation resulting in the catabolism of glucose to propionate, yielding energy in the form of ATP; an alternative to the acrylate pathway to produce propionate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0099509", "l": "regulation of presynaptic cytosolic calcium ion concentration", "d": ["Any process that regulates the concentration of calcium in the presynaptic cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061329", "l": "Malpighian tubule principal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006844", "l": "acyl carnitine transport", "d": ["The directed movement of acyl carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:2000036", "l": "regulation of stem cell population maintenance", "d": ["Any process that modulates the frequency, rate or extent of stem cell population maintenance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0032971", "l": "regulation of muscle filament sliding", "d": ["Any process that modulates the frequency, rate or extent of muscle filament sliding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0009263", "l": "deoxyribonucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903553", "l": "positive regulation of extracellular exosome assembly", "d": ["Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060289", "l": "compartment boundary maintenance", "d": ["A homeostatic process involved in the maintenance of a compartment boundary. A compartment boundary is a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010122", "l": "arginine catabolic process to alanine via ornithine", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including alanine, via ornithine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0035141", "l": "medial fin morphogenesis", "d": ["The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002539", "l": "prostaglandin production involved in inflammatory response", "d": ["The synthesis or release of any prostaglandin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071644", "l": "negative regulation of chemokine (C-C motif) ligand 4 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900345", "l": "regulation of methane biosynthetic process from methanethiol", "d": ["Any process that modulates the frequency, rate or extent of methane biosynthetic process from methanethiol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0009130", "l": "pyrimidine nucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060845", "l": "venous endothelial cell fate commitment", "d": ["The commitment of a cell to a venous endothelial cell fate and its capacity to differentiate into an venous endothelial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048710", "l": "regulation of astrocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of astrocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0032072", "l": "regulation of restriction endodeoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046501", "l": "protoporphyrinogen IX metabolic process", "d": ["The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.232064878529073", "identifiers": [{"i": "GO:0019941", "l": "modification-dependent protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0043419", "l": "urea catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of urea, the water soluble compound O=C-(NH2)2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010711", "l": "negative regulation of collagen catabolic process", "d": ["Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901918", "l": "negative regulation of exoribonuclease activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of exoribonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0072012", "l": "glomerulus vasculature development", "d": ["The biological process whose specific outcome is the progression of a glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the glomerulus vasculature and ends with the mature structure. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120272", "l": "positive regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts", "d": ["Any process that activates or increases the frequency, rate or extent of degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010509", "l": "intracellular polyamine homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of polyamine within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051461", "l": "positive regulation of corticotropin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin hormone from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051548", "l": "negative regulation of keratinocyte migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900226", "l": "negative regulation of NLRP3 inflammasome complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0016100", "l": "monoterpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of monoterpenoid compounds, terpenoids having a C10 skeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901887", "l": "2-hydroxybenzoyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 2-hydroxybenzoyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070446", "l": "negative regulation of oligodendrocyte progenitor proliferation", "d": ["Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0045061", "l": "thymic T cell selection", "d": ["The process of T cell selection that occurs in the thymus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0014897", "l": "striated muscle hypertrophy", "d": ["The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0110011", "l": "regulation of basement membrane organization", "d": ["Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0044578", "l": "butyryl-CoA biosynthetic process", "d": ["The chemical reactions and pathway resulting in the formation of butyryl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0032071", "l": "regulation of endodeoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160040", "l": "mitocytosis", "d": ["A migrasome-mediated selective removal of damaged mitochondria process that maintains mitochondrion homeostasis in migrating cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035330", "l": "regulation of hippo signaling", "d": ["Any process that modulates the frequency, rate or extent of hippo signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016554", "l": "cytidine to uridine editing", "d": ["The conversion of a cytosine residue to uridine in an RNA molecule by deamination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900355", "l": "negative regulation of methanofuran metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0070640", "l": "vitamin D3 metabolic process", "d": ["The chemical reactions and pathways involving vitamin D3, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046601", "l": "positive regulation of centriole replication", "d": ["Any process that activates or increases the frequency, rate or extent of centriole replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0043409", "l": "negative regulation of MAPK cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042837", "l": "D-glucarate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-glucarate, the D-enantiomer of glucarate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001999", "l": "renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure", "d": ["The physiological response of the kidneys to a decrease in blood flow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032715", "l": "negative regulation of interleukin-6 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900865", "l": "chloroplast RNA modification", "d": ["Any RNA modification that takes place in chloroplast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000255", "l": "negative regulation of male germ cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900625", "l": "positive regulation of monocyte aggregation", "d": ["Any process that activates or increases the frequency, rate or extent of monocyte aggregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010995", "l": "free ubiquitin chain depolymerization", "d": ["The process in which free ubiquitin chains, compounds composed of a large number of ubiquitin monomers, are broken down."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0075298", "l": "regulation of zygospore formation", "d": ["Any process that modulates the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905326", "l": "positive regulation of meiosis I spindle assembly checkpoint", "d": ["Any process that activates or increases the frequency, rate or extent of the meiosis I spindle assembly checkpoint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019656", "l": "glucose catabolic process to D-lactate and ethanol", "d": ["The anaerobic chemical reactions and pathways resulting in the enzymatic breakdown of D-glucose to D-lactate and ethanol, yielding energy in the form of adenosine triphosphate (ATP) at the rate of one ATP per glucose molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042818", "l": "pyridoxamine metabolic process", "d": ["The chemical reactions and pathways involving 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901152", "l": "vistamycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of vistamycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0120248", "l": "acetylenic compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903512", "l": "phytanic acid metabolic process", "d": ["The chemical reactions and pathways involving phytanic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010315", "l": "auxin export across the plasma membrane", "d": ["The directed movement of auxins from inside of a cell, across the plasma membrane and into the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042067", "l": "establishment of ommatidial planar polarity", "d": ["The specification of polarized ommatidia. Ommatidia occur in two chiral forms. The trapezoidal arrangement of photoreceptors in the dorsal part of the eye is the mirror image of that in the ventral part."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051679", "l": "6-alpha-maltosylglucose metabolic process", "d": ["The chemical reactions and pathways involving 6-alpha-maltosylglucose, also known as isopanose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051456", "l": "attachment of spindle microtubules to kinetochore involved in meiotic sister chromatid segregation", "d": ["The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis II. During meiosis II sister kinetochores are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903745", "l": "negative regulation of pharyngeal pumping", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pharyngeal pumping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000727", "l": "double-strand break repair via break-induced replication", "d": ["The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034971", "l": "histone H3-R17 methylation", "d": ["The modification of histone H3 by addition of a methyl group to arginine at position 17 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0060631", "l": "regulation of meiosis I", "d": ["Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003038", "l": "detection of reduced oxygen by aortic body chemoreceptor signaling", "d": ["The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in an aortic body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0051709", "l": "regulation of killing of cells of another organism", "d": ["Any process that modulates the frequency, rate or extent of the killing by an organism of cells in another organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098908", "l": "regulation of neuronal action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002594", "l": "positive regulation of antigen processing and presentation via MHC class Ib", "d": ["Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905796", "l": "regulation of intraciliary anterograde transport", "d": ["Any process that modulates the frequency, rate or extent of intraciliary anterograde transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0038099", "l": "nodal receptor complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a complex containing a type II activin receptor, a type I activin receptor, and a coreceptor of the EGF-CFC family (e.g. Cripto or Cryptic, in mammals)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080001", "l": "mucilage extrusion from seed coat", "d": ["The process in which seed mucilage expands through hydration and breaks the outer cell wall that encapsulates the whole seed upon imbibition. Mucilage, mainly composed of pectins, is formed during seed development and deposited into the apoplast underneath the outer wall of the seed coat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021773", "l": "striatal medium spiny neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a medium spiny neuron residing in the striatum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.000891501185137", "identifiers": [{"i": "GO:0051047", "l": "positive regulation of secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0061119", "l": "regulation of positive chemotaxis to cAMP by chlorinated alkylphenone", "d": ["Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032336", "l": "negative regulation of activin secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of activin from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033630", "l": "positive regulation of cell adhesion mediated by integrin", "d": ["Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010914", "l": "positive regulation of sterigmatocystin biosynthetic process", "d": ["Any process that increases the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071593", "l": "lymphocyte aggregation", "d": ["The adhesion of one lymphocyte to one or more other lymphocytes via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009697", "l": "salicylic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0030451", "l": "regulation of complement activation, alternative pathway", "d": ["Any process that modulates the frequency, rate or extent of the alternative pathway of complement activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010744", "l": "positive regulation of macrophage derived foam cell differentiation", "d": ["Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019084", "l": "middle viral transcription", "d": ["The viral transcription that takes place after early transcription in the viral life cycle, and which involves the transcription of genes required for replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062195", "l": "microtubule bundle maintenance", "d": ["The organization process that preserves a microtubule bundle in a stable functional or structural state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904682", "l": "cellular response to 3-methylcholanthrene", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046877", "l": "regulation of saliva secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of saliva from a cell or a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902132", "l": "(+)-lariciresinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (+)-lariciresinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006069", "l": "ethanol oxidation", "d": ["An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0006929", "l": "substrate-dependent cell migration", "d": ["The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000919", "l": "negative regulation of glucuronoarabinoxylan catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoarabinoxylan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072040", "l": "negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis", "d": ["Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904975", "l": "response to bleomycin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.504352937422851", "identifiers": [{"i": "GO:0033044", "l": "regulation of chromosome organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0014848", "l": "urinary tract smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901266", "l": "cephalosporin C metabolic process", "d": ["The chemical reactions and pathways involving cephalosporin C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904917", "l": "L-arginine transmembrane transport from lysosomal lumen to cytosol", "d": ["The directed movement of L-arginine across a membrane from lysosomal lumen to cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045040", "l": "protein insertion into mitochondrial outer membrane", "d": ["The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000927", "l": "regulation of cellodextrin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellodextrin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071984", "l": "maintenance of reproductive diapause", "d": ["The dormancy process that results an organism remaining in reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060378", "l": "regulation of brood size", "d": ["Any process that modulates brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0044038", "l": "cell wall macromolecule biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060099", "l": "regulation of phagocytosis, engulfment", "d": ["Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0051590", "l": "positive regulation of neurotransmitter transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905724", "l": "positive regulation of trypanothione biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of trypanothione biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044735", "l": "envenomation resulting in negative regulation of acid-sensing ion channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072734", "l": "cellular response to staurosporine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1900787", "l": "naphtho-gamma-pyrone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of naphtho-gamma-pyrone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010515", "l": "negative regulation of induction of conjugation with cellular fusion", "d": ["Any process that stops, prevents, or reduces the frequency or rate of initiation of conjugation with cellular fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903645", "l": "negative regulation of chaperone-mediated protein folding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated protein folding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031133", "l": "regulation of axon diameter", "d": ["Any process that modulates the rate, direction or extent of axon growth such that the correct diameter is attained and maintained."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042683", "l": "negative regulation of compound eye cone cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from specifying into a compound eye cone cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072700", "l": "response to bismuth", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0061339", "l": "establishment or maintenance of monopolar cell polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904904", "l": "regulation of endothelial cell-matrix adhesion via fibronectin", "d": ["Any process that modulates the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061948", "l": "premature acrosome loss", "d": ["The discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048201", "l": "vesicle targeting, plasma membrane to endosome", "d": ["The process in which vesicles formed at the plasma membrane are directed to specific destinations in endosome membranes, mediated by molecules at the vesicle membrane and target membrane surfaces."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006046", "l": "N-acetylglucosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0002637", "l": "regulation of immunoglobulin production", "d": ["Any process that modulates the frequency, rate, or extent of immunoglobulin production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0034198", "l": "cellular response to amino acid starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070983", "l": "dendrite guidance", "d": ["The process in which the migration of a dendrite is directed to a specific target site in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0031120", "l": "snRNA pseudouridine synthesis", "d": ["The intramolecular conversion of uridine to pseudouridine in an snRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905722", "l": "regulation of trypanothione biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of trypanothione biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033324", "l": "choline biosynthetic process via N-monomethylethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate N-monomethylethanolamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046711", "l": "GDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GDP, guanosine 5'-diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051142", "l": "positive regulation of NK T cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090275", "l": "negative regulation of somatostatin secretion", "d": ["Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021810", "l": "neurotransmitter signaling initiating cell movement, involved in cerebral cortex radial glia guided migration", "d": ["Signaling by neurotransmitters and their receptors that results in the initiation of movement of cells as a component of the process of glial-mediated radial migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035616", "l": "histone H2B conserved C-terminal lysine deubiquitination", "d": ["A histone deubiquitination process in which a ubiquitin monomer is removed from a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009689", "l": "induction of phytoalexin biosynthetic process", "d": ["The activation of the chemical reactions and pathways resulting in the formation of phytoalexins, low-molecular mass, lipophilic antimicrobial compounds that accumulate rapidly at sites of incompatible pathogen infection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903592", "l": "positive regulation of lysozyme activity", "d": ["Any process that activates or increases the frequency, rate or extent of lysozyme activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000978", "l": "negative regulation of forebrain neuron differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009722", "l": "detection of cytokinin stimulus", "d": ["The series of events in which a cytokinin stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0099017", "l": "maintenance of protein localization at cell tip", "d": ["Any process in which localization of a protein is maintained at the cell tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904491", "l": "protein localization to ciliary transition zone", "d": ["A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0051238", "l": "sequestering of metal ion", "d": ["The process of binding or confining metal ions such that they are separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900502", "l": "positive regulation of butyryl-CoA catabolic process to butyrate", "d": ["Any process that activates or increases the frequency, rate or extent of butyryl-CoA catabolic process to butyrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0008210", "l": "estrogen metabolic process", "d": ["The chemical reactions and pathways involving estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902876", "l": "negative regulation of embryonic pattern specification", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902631", "l": "negative regulation of membrane hyperpolarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane hyperpolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019087", "l": "transformation of host cell by virus", "d": ["A virus-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0060896", "l": "neural plate pattern specification", "d": ["The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046745", "l": "viral capsid secondary envelopment", "d": ["The process in which a capsid acquires another membrane envelope, subsequent to acquiring an initial membrane envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042704", "l": "uterine wall breakdown", "d": ["The sloughing of the endometrium and blood vessels during menstruation that results from a drop in progesterone levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002575", "l": "basophil chemotaxis", "d": ["The movement of a basophil in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075527", "l": "viral RNA editing", "d": ["The process by which bases in viral mRNA are chemically altered during viral transcription. This is usually the incorporation of 1 - 6 additional nucleotides, which shifts the reading frame, allowing the generation of different protein products or through a specific nucleotide change that eliminates the termination codon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0040028", "l": "regulation of vulval development", "d": ["Any process that modulates the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900207", "l": "negative regulation of pronephric nephron tubule development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902396", "l": "protein localization to bicellular tight junction", "d": ["A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010414", "l": "glucuronoarabinoxylan metabolic process", "d": ["The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid and arabinose side units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901802", "l": "1,5-anhydro-D-fructose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1,5-anhydro-D-fructose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032475", "l": "otolith formation", "d": ["The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018360", "l": "protein-heme P460 linkage via heme P460-bis-L-cysteine-L-lysine", "d": ["The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018976", "l": "1,2,3-tribromopropane metabolic process", "d": ["The chemical reactions and pathways involving 1,2,3-tribromopropane, a toxic and volatile organic compound commonly used as a nematocide in agriculture."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0036182", "l": "asperthecin metabolic process", "d": ["The chemical reactions and pathways involving asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019276", "l": "UDP-N-acetylgalactosamine metabolic process", "d": ["The chemical reactions and pathways involving UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070236", "l": "negative regulation of activation-induced cell death of T cells", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of activation-induced cell death of T cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900713", "l": "regulation of violaceol I biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of violaceol I biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048204", "l": "vesicle targeting, inter-Golgi cisterna", "d": ["The process in which vesicles are directed to specific destination membranes during transport from one Golgi cisterna to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990397", "l": "queuosine salvage", "d": ["Any process which produces queuosine from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0036089", "l": "cleavage furrow formation", "d": ["Generation of the cleavage furrow, a shallow groove in the cell surface near the old metaphase plate that marks the site of cytokinesis. This process includes the recruitment and localized activation of signals such as RhoA at the site of the future furrow to ensure that furrowing initiates at the correct site in the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001781", "l": "neutrophil apoptotic process", "d": ["Any apoptotic process in a neutrophil, any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036146", "l": "cellular response to mycotoxin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032474", "l": "otolith morphogenesis", "d": ["The process in which the anatomical structures of an otolith are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061150", "l": "renal system segmentation", "d": ["The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031077", "l": "post-embryonic camera-type eye development", "d": ["The process occurring during the post-embryonic phase whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903109", "l": "positive regulation of mitochondrial transcription", "d": ["Any process that activates or increases the frequency, rate or extent of transcription occuring in the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0039021", "l": "pronephric glomerulus development", "d": ["The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034055", "l": "effector-mediated induction of programmed cell death in host", "d": ["A symbiont process in which a molecule secreted by the symbiont activates a programmed cell death pathway in the host to suppress the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.071082486141265", "identifiers": [{"i": "GO:0030856", "l": "regulation of epithelial cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of epithelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0051081", "l": "nuclear membrane disassembly", "d": ["The controlled breakdown of the nuclear membranes, for example during cellular division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035803", "l": "egg coat formation", "d": ["Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055110", "l": "involution involved in gastrulation with mouth forming second", "d": ["The inturning of an epithelial sheet over the basal surface of an outer layer involved in deuterostomic gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904240", "l": "negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070146", "l": "mitochondrial aspartyl-tRNA aminoacylation", "d": ["The process of coupling aspartate to aspartyl-tRNA in a mitochondrion, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.824513090543306", "identifiers": [{"i": "GO:0033500", "l": "carbohydrate homeostasis", "d": ["A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0061559", "l": "cranial ganglion morphogenesis", "d": ["The process in which the anatomical structure of a cranial ganglion is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0089705", "l": "protein localization to outer membrane", "d": ["A process in which a protein is transported to, or maintained in, a specific location the cell outer membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051573", "l": "negative regulation of histone H3-K9 methylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0031154", "l": "culmination involved in sorocarp development", "d": ["The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0006572", "l": "tyrosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045863", "l": "negative regulation of pteridine metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pteridine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046880", "l": "regulation of follicle-stimulating hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of follicle-stimulating hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030908", "l": "protein splicing", "d": ["The post-translational removal of peptide sequences from within a protein sequence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099121", "l": "fungal sorus development", "d": ["The process whose specific outcome is the progression of a fungal sorus over time, from its formation to the mature structure. A fungal sorus is a spore containing structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071037", "l": "nuclear polyadenylation-dependent snRNA catabolic process", "d": ["The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nuclear RNA (snRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141024", "l": "adhesion of symbiont to host cell surface via host membrane carbohydrate", "d": ["The attachment of a symbiont to its host by binding to a carbohydrate on the host cell surface. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019382", "l": "carbon tetrachloride catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.139845358389962", "identifiers": [{"i": "GO:0048667", "l": "cell morphogenesis involved in neuron differentiation", "d": ["The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002729", "l": "positive regulation of natural killer cell cytokine production", "d": ["Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905434", "l": "positive regulation of retrograde trans-synaptic signaling by neuropeptide", "d": ["Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070495", "l": "negative regulation of thrombin-activated receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0071324", "l": "cellular response to disaccharide stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0000398", "l": "mRNA splicing, via spliceosome", "d": ["The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043479", "l": "pigment accumulation in tissues in response to UV light", "d": ["The aggregation of coloring matter in a particular location in a tissue, occurring in response to a UV light stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "60.689198976159247", "identifiers": [{"i": "GO:0003002", "l": "regionalization", "d": ["The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0060465", "l": "pharynx development", "d": ["The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006017", "l": "deoxyribose 1,5-bisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.290269238295835", "identifiers": [{"i": "GO:1990778", "l": "protein localization to cell periphery", "d": ["A process in which a protein is transported to, or maintained in, the cell periphery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098689", "l": "latency-replication decision", "d": ["The process by which a virus switches on its replication cycle in an infected cell.  The process is typically controlled by a genetic swtich controlled by environmental factors such as cell type, cell shape, the availability of nutrients, superinfection or exposure of infected cells to UV or various chemical stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0010761", "l": "fibroblast migration", "d": ["Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0005995", "l": "melibiose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904588", "l": "cellular response to glycoprotein", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032214", "l": "negative regulation of telomere maintenance via semi-conservative replication", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014054", "l": "positive regulation of gamma-aminobutyric acid secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0043570", "l": "maintenance of DNA repeat elements", "d": ["Any process involved in sustaining the fidelity and copy number of DNA repeat elements."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006249", "l": "dCMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dCMP, deoxycytidine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002117", "l": "amphibian larval development", "d": ["The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0150076", "l": "neuroinflammatory response", "d": ["The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033631", "l": "cell-cell adhesion mediated by integrin", "d": ["The attachment of one cell to another cell via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048845", "l": "venous blood vessel morphogenesis", "d": ["The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071043", "l": "CUT metabolic process", "d": ["The chemical reactions and pathways involving cryptic unstable transcripts (CUTs), which are transcribed from intergenic regions. Many intergenic regions are heavily transcribed, but the transcripts are rarely detected due to rapid degradation by the nuclear exosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1901317", "l": "regulation of flagellated sperm motility", "d": ["Any process that modulates the frequency, rate or extent of flagellated sperm motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061556", "l": "trigeminal ganglion morphogenesis", "d": ["The process in which the anatomical structure of a trigeminal ganglion is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0070813", "l": "hydrogen sulfide metabolic process", "d": ["The chemical reactions and pathways involving hydrogen sulfide, H2S."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903327", "l": "negative regulation of tRNA metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0000711", "l": "meiotic DNA repair synthesis", "d": ["During meiosis, the synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000111", "l": "positive regulation of macrophage apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0120235", "l": "regulation of post-translational protein targeting to membrane, translocation", "d": ["Any process that modulates the frequency, rate or extent of posttranslational protein translocation through the ER membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018936", "l": "anaerobic nitrilotriacetate metabolic process", "d": ["The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002038", "l": "positive regulation of L-glutamate import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of L-glutamate import into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042252", "l": "establishment of planar polarity of larval imaginal disc epithelium", "d": ["Coordinated organization of groups of cells in the plane of a larval imaginal disc epithelium, such that they all orient to similar coordinates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090240", "l": "positive regulation of histone H4 acetylation", "d": ["Any process that increases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0050923", "l": "regulation of negative chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019463", "l": "glycine catabolic process to creatine", "d": ["The chemical reactions and pathways resulting in the breakdown of glycine into other compounds, including creatine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070366", "l": "regulation of hepatocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of hepatocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009906", "l": "response to photoperiod, blue light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a blue light photoperiod stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002478", "l": "antigen processing and presentation of exogenous peptide antigen", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.69196672140982", "identifiers": [{"i": "GO:0030030", "l": "cell projection organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060854", "l": "branching involved in lymph vessel morphogenesis", "d": ["The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062038", "l": "positive regulation of pheromone response MAPK cascade", "d": ["Any process that activates or increases the frequency, rate or extent of a pheromone response MAPK cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0030540", "l": "female genitalia development", "d": ["The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902761", "l": "positive regulation of chondrocyte development", "d": ["Any process that activates or increases the frequency, rate or extent of chondrocyte development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030035", "l": "microspike assembly", "d": ["Formation of a microspike, a dynamic, actin-rich projection extending from the surface of a migrating animal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.330951936344348", "identifiers": [{"i": "GO:0090066", "l": "regulation of anatomical structure size", "d": ["Any process that modulates the size of an anatomical structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015939", "l": "pantothenate metabolic process", "d": ["The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902894", "l": "negative regulation of miRNA transcription", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microRNA (miRNA) gene transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0002590", "l": "negative regulation of antigen processing and presentation of peptide antigen via MHC class I", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000233", "l": "negative regulation of rRNA processing", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060714", "l": "labyrinthine layer formation", "d": ["The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015783", "l": "GDP-fucose transmembrane transport", "d": ["The directed movement of GDP-fucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140217", "l": "positive regulation of D-aspartate import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060876", "l": "semicircular canal formation", "d": ["The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141014", "l": "ribosome hibernation", "d": ["A cellular process that results in the silencing of ribosomes in quiescent cells. Quiescence takes place when cells encounter unfavorable conditions and cease to grow in bacteria and yeast. It also takes place in some specialized cells in higher eukaryotes, such as eggs. Ribosomes in a hibernation state are kept silent via association with proteins with inhibitory and protective functions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0033566", "l": "gamma-tubulin complex localization", "d": ["Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0015808", "l": "L-alanine transport", "d": ["The directed movement of L-alanine, the L-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905550", "l": "regulation of protein localization to endoplasmic reticulum", "d": ["Any process that modulates the frequency, rate or extent of protein localization to endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0010765", "l": "positive regulation of sodium ion transport", "d": ["Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071041", "l": "antisense RNA transcript catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of antisense transcripts, i.e. transcripts that were produced from the antisense strand of a gene that produces a gene product and which often have a regulatory effect on the transcription of that gene product."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0062164", "l": "regulation of pseudohyphal septin ring assembly", "d": ["Any process that modulates the rate, frequency or extent of pseudohyphal septin ring assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045643", "l": "regulation of eosinophil differentiation", "d": ["Any process that modulates the frequency, rate or extent of eosinophil differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031247", "l": "actin rod assembly", "d": ["The assembly of actin rods, a cellular structure consisting of parallel, hexagonally arranged actin tubules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018232", "l": "peptide cross-linking via S-(L-isoglutamyl)-L-cysteine", "d": ["The modification of peptidyl-glutamine and peptidyl-cysteine to form a S-(L-isoglutamyl)-L-cysteine protein cross-link."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904299", "l": "negative regulation of transcytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transcytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0003260", "l": "cardioblast migration", "d": ["The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071557", "l": "histone H3-K27 demethylation", "d": ["The modification of histone H3 by the removal of a methyl group from lysine at position 27 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0030308", "l": "negative regulation of cell growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905012", "l": "regulation of 'de novo' NAD biosynthetic process from tryptophan", "d": ["Any process that modulates the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046646", "l": "regulation of gamma-delta T cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of gamma-delta T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032684", "l": "negative regulation of fractalkine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of fractalkine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099608", "l": "regulation of action potential firing pattern", "d": ["Any process that regulates the temporal pattern of a sequence of action potentials in a neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0003353", "l": "positive regulation of cilium movement", "d": ["Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031115", "l": "negative regulation of microtubule polymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000564", "l": "regulation of CD8-positive, alpha-beta T cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:1902622", "l": "regulation of neutrophil migration", "d": ["Any process that modulates the frequency, rate or extent of neutrophil migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048833", "l": "specification of floral organ number", "d": ["Any process that modulates the number of floral organs formed in a floral whorl."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0031018", "l": "endocrine pancreas development", "d": ["The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0032776", "l": "DNA methylation on cytosine", "d": ["The covalent transfer of a methyl group to C-5 or N-4 of cytosine in a DNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031654", "l": "regulation of heat dissipation", "d": ["Any process that modulates the rate or extent of heat dissipation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009876", "l": "pollen adhesion", "d": ["The process in which pollen deposited on the stigma adheres to cells of the stigma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032226", "l": "positive regulation of synaptic transmission, dopaminergic", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034133", "l": "positive regulation of toll-like receptor 1 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 1 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070130", "l": "negative regulation of mitochondrial translation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0045989", "l": "positive regulation of striated muscle contraction", "d": ["Any process that activates or increases the frequency, rate or extent of striated muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044525", "l": "peptidyl-cystine sulfhydration", "d": ["The modification of a peptidyl-cystine residue in a protein by the addition of sulfur, to form peptidyl-cysteine persulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:1903035", "l": "negative regulation of response to wounding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042183", "l": "formate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990705", "l": "cholangiocyte proliferation", "d": ["The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0016189", "l": "synaptic vesicle to endosome fusion", "d": ["Fusion of a synaptic vesicle with an endosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010346", "l": "shoot axis formation", "d": ["The process that gives rise to a shoot axis. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035740", "l": "CD8-positive, alpha-beta T cell proliferation", "d": ["The expansion of a CD8-positive, alpha-beta T cell population by cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140641", "l": "mitotic spindle formation (spindle phase two)", "d": ["The spindle organization process in which the spindle is maintained at a constant length during mitotic metaphase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060975", "l": "cardioblast migration to the midline involved in heart field formation", "d": ["The orderly movement of a cardioblast toward the midline to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905442", "l": "cellular response to chondroitin 4'-sulfate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0021923", "l": "cell proliferation in hindbrain ventricular zone", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain region that is adjacent to the ventricular cavity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061452", "l": "retrotrapezoid nucleus neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990388", "l": "xylem-to-phloem iron transport", "d": ["The directed movement of iron ions into the phloem from the xylem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075000", "l": "response to host osmotic environment", "d": ["Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the osmotic conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:2000197", "l": "regulation of ribonucleoprotein complex localization", "d": ["Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905688", "l": "negative regulation of diacylglycerol kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0046639", "l": "negative regulation of alpha-beta T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.357413409522593", "identifiers": [{"i": "GO:0120039", "l": "plasma membrane bounded cell projection morphogenesis", "d": ["The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904197", "l": "positive regulation of granulosa cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of granulosa cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035570", "l": "N-terminal peptidyl-serine methylation", "d": ["The methylation of the N-terminal serine of proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0070918", "l": "regulatory ncRNA processing", "d": ["A process leading to the generation of a functional regulatory non-coding RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110134", "l": "meiotic drive", "d": ["A biological process that results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to gametes. In the absence of meiotic drive, the two copies of each gene or chromosome in a diploid organism are transmitted to offspring with equal probability, whereas meiotic drive results in overrepresentation of the driving allele among the surviving products of meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048722", "l": "anterior cibarial plate development", "d": ["The process whose specific outcome is the progression of the anterior cibarial plate over time, from their formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075239", "l": "zoospore formation", "d": ["The process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0070229", "l": "negative regulation of lymphocyte apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018257", "l": "peptidyl-lysine formylation", "d": ["The modification of peptidyl-lysine to form peptidyl-N6-formyl-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000232", "l": "regulation of rRNA processing", "d": ["Any process that modulates the frequency, rate or extent of rRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0009070", "l": "serine family amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901212", "l": "positive regulation of cardiac chamber formation", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac chamber formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901275", "l": "tartrate metabolic process", "d": ["The chemical reactions and pathways involving tartrate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1901343", "l": "negative regulation of vasculature development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0033306", "l": "phytol metabolic process", "d": ["The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901780", "l": "pentalenolactone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pentalenolactone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001192", "l": "maintenance of transcriptional fidelity during transcription elongation", "d": ["Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation on a DNA template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0039664", "l": "lysis of host organelle involved in viral entry into host cell", "d": ["The viral-induced lysis of an organelle (endosome, lysosome, or caveosome) that is involved in the uptake of a virus into a host cell. Occurs once the virus is within the organelle, and results in transfer of the viral contents from the organelle compartment into the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010245", "l": "radial microtubular system formation", "d": ["Formation of radial microtubular systems during male meiotic cytokinesis in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060318", "l": "definitive erythrocyte differentiation", "d": ["Erythrocyte differentiation which occurs as part of the process of definitive hemopoiesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902332", "l": "bacterial-type DNA replication DNA duplex unwinding", "d": ["Any DNA duplex unwinding that is involved in bacterial-type DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0090023", "l": "positive regulation of neutrophil chemotaxis", "d": ["Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070564", "l": "positive regulation of vitamin D receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of vitamin D receptor signaling pathway activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060514", "l": "prostate induction", "d": ["The close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051872", "l": "sphingosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000448", "l": "cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage within ITS2 between the 5.8S rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036485", "l": "dorsolateral trunk neural crest cell migration", "d": ["The movement of trunk neural crest cells from the neural tube, travelling dorso-laterally into the ectoderm and continuing toward the ventral midline of the belly. These migrating trunk neural crest cells become melanocytes, the melanin-forming pigment cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034221", "l": "fungal-type cell wall chitin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0030650", "l": "peptide antibiotic metabolic process", "d": ["The chemical reactions and pathways involving peptides with antibiotic activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043376", "l": "regulation of CD8-positive, alpha-beta T cell differentiation", "d": ["Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1901632", "l": "regulation of synaptic vesicle membrane organization", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle membrane organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051642", "l": "centrosome localization", "d": ["Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000361", "l": "regulation of prostaglandin-E synthase activity", "d": ["Any process that modulates the frequency, rate or extent of prostaglandin-E synthase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018893", "l": "dibenzofuran metabolic process", "d": ["The chemical reactions and pathways involving dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond. Dibenzofuran is a white crystalline solid created from the production of coal tar and used as an insecticide and an intermediate in the production of other chemicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030913", "l": "paranodal junction assembly", "d": ["Formation of the junction between an axon and the glial cell that forms the myelin sheath. Paranodal junctions form at each paranode, i.e. at the ends of the unmyelinated nodes of Ranvier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048726", "l": "labrum development", "d": ["The process whose specific outcome is the progression of the labrum over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904833", "l": "positive regulation of removal of superoxide radicals", "d": ["Any process that activates or increases the frequency, rate or extent of removal of superoxide radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0086092", "l": "regulation of the force of heart contraction by cardiac conduction", "d": ["A cardiac conduction process that modulates the extent of heart contraction, changing the force with which blood is propelled."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901749", "l": "leukotriene D4 catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of leukotriene D4."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0021987", "l": "cerebral cortex development", "d": ["The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002655", "l": "regulation of tolerance induction to nonself antigen", "d": ["Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901153", "l": "paromomycin metabolic process", "d": ["The chemical reactions and pathways involving paromomycin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0051957", "l": "positive regulation of amino acid transport", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0015857", "l": "uracil transport", "d": ["The directed movement of uracil, 2,4-dioxopyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902232", "l": "regulation of positive thymic T cell selection", "d": ["Any process that modulates the frequency, rate or extent of positive thymic T cell selection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1904505", "l": "regulation of telomere maintenance in response to DNA damage", "d": ["Any process that modulates the frequency, rate or extent of telomere maintenance in response to DNA damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048347", "l": "negative regulation of paraxial mesodermal cell fate determination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140455", "l": "cytoplasm protein quality control", "d": ["The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are either targeted to cytoplasmic proteasomes for degradation or protected by chaperones to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902738", "l": "regulation of chondrocyte differentiation involved in endochondral bone morphogenesis", "d": ["Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901162", "l": "primary amino compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of primary amino compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010270", "l": "photosystem II oxygen evolving complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the oxygen evolving complex (OEC) of photosystem II on a thylakoid membrane. The OEC protects the calcium-4 manganese-5 oxide cluster which is bound to the D1 and CP43 proteins. The exact protein composition of the OEC varies between cyanobacteria and plants, and in plants consists of three extrinsic nuclear-encoded polypeptides: PsbO, PsbP and PsbQ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000538", "l": "positive regulation of B cell chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of B cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032952", "l": "regulation of (1->3)-beta-D-glucan metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-beta-D-glucans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0014741", "l": "negative regulation of muscle hypertrophy", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905588", "l": "plant-type cell wall modification involved in stomatal movement", "d": ["Any plant-type cell wall modification that is involved in stomatal movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0016556", "l": "mRNA modification", "d": ["The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.232064878529073", "identifiers": [{"i": "GO:0001539", "l": "cilium or flagellum-dependent cell motility", "d": ["Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150138", "l": "negative regulation of interleukin-37 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-37 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001971", "l": "negative regulation of activation of membrane attack complex", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045231", "l": "slime layer organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a slime layer. A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903580", "l": "positive regulation of ATP metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of ATP metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140300", "l": "serine import into mitochondrion", "d": ["The process in which serine is transported from the cytosol into the mitochondrial matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017193", "l": "N-terminal peptidyl-glycine acetylation", "d": ["The acetylation of the N-terminal glycine of proteins to form the derivative N-acetylglycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090472", "l": "dibasic protein processing", "d": ["Any protein processing achieved by the cleavage of a peptide bond after two basic amino acids within a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.542510287032449", "identifiers": [{"i": "GO:0032101", "l": "regulation of response to external stimulus", "d": ["Any process that modulates the frequency, rate or extent of a response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033380", "l": "granzyme B localization to T cell secretory granule", "d": ["Any process in which the protease granzyme B is transported to, or maintained in, a location within a secretory granule in a T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905589", "l": "positive regulation of L-arginine import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of L-arginine import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097173", "l": "N-acetylmuramic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002852", "l": "regulation of T cell mediated cytotoxicity directed against tumor cell target", "d": ["Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035202", "l": "tracheal pit formation in open tracheal system", "d": ["Formation of the tracheal pits, the first tube-like structures to form in the open tracheal system. Once cells are determined to their tracheal cell fate, the tracheal pits arise by invagination of each ectodermal cluster of tracheal placode cells, between 5 and 7 hours after egg laying. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062088", "l": "negative regulation of vein smooth muscle contraction", "d": ["Any process that decreases the frequency, rate or extent of vein smooth muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0005978", "l": "glycogen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021837", "l": "motogenic signaling involved in postnatal olfactory bulb interneuron migration", "d": ["The signaling that results in the stimulation of cell movement in the rostral migratory stream."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060168", "l": "positive regulation of adenosine receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0052698", "l": "ergothioneine metabolic process", "d": ["The chemical reactions and pathways involving ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900332", "l": "positive regulation of methane biosynthetic process from trimethylamine", "d": ["Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from trimethylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046845", "l": "branched duct epithelial cell fate determination, open tracheal system", "d": ["Allocation of a set number of cells to each primary branch in an open tracheal system, prior to the onset of cell migration. This establishes different domains of cells within the tracheal placode."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032771", "l": "regulation of tyrosinase activity", "d": ["Any process that modulates the activity of a tyrosinase enzyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021615", "l": "glossopharyngeal nerve morphogenesis", "d": ["The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046452", "l": "dihydrofolate metabolic process", "d": ["The chemical reactions and pathways involving dihydrofolate, the dihydroxylated derivative of folate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904244", "l": "positive regulation of pancreatic trypsinogen secretion", "d": ["Any process that activates or increases the frequency, rate or extent of pancreatic trypsinogen secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070630", "l": "(1->4)-alpha-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0030432", "l": "peristalsis", "d": ["A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006378", "l": "mRNA polyadenylation", "d": ["The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.232064878529073", "identifiers": [{"i": "GO:0048333", "l": "mesodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072294", "l": "specification of metanephric connecting tubule identity", "d": ["The process in which the connecting tubule of the metanephric nephron acquires its identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0045822", "l": "negative regulation of heart contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031041", "l": "O-glycan processing, core 5", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 5 O-glycan structure, GalNAc-alpha-(1->3)-GalNAc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071592", "l": "nicotinic acid riboside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003408", "l": "optic cup formation involved in camera-type eye development", "d": ["The developmental process pertaining to the initial formation of the optic cup, a two-walled vesicle formed from the optic vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000829", "l": "negative regulation of parathyroid hormone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of parathyroid hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0039562", "l": "disruption by virus of host JAK-STAT cascade via inhibition of STAT activity", "d": ["Any process in which a virus interferes with a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT (signal transducer and activator of transcription). STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048613", "l": "embryonic ectodermal digestive tract morphogenesis", "d": ["The process, occurring during the embryonic phase, by which the anatomical structures of the ectodermal digestive tract are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044844", "l": "meiotic interphase II", "d": ["The cell cycle phase which begins at the end of meiosis I cytokinesis and ends when meiosis II prophase begins. During meiotic interphase II no DNA replication takes place, but the centrioles duplicate and spindle fibres emerge."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000171", "l": "negative regulation of dendrite development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0070793", "l": "regulation of conidiophore development", "d": ["Any process that modulates the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070147", "l": "mitochondrial cysteinyl-tRNA aminoacylation", "d": ["The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048058", "l": "compound eye corneal lens development", "d": ["The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035067", "l": "negative regulation of histone acetylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to a histone protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090164", "l": "asymmetric Golgi ribbon formation", "d": ["The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that contributes to the establishment of epithelial cell polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039639", "l": "suppression by virus of host cell lysis in response to superinfection", "d": ["The prevention or delay of host cell lysis by a pre-existing virus in response to a subsequent infection of the host cell by second virus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0099135", "l": "chimeric colonial development", "d": ["Development a structure consisting of multiple co-operating unicellular organisms of the same species, involving cells of more that one genotype."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035900", "l": "response to isolation stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045756", "l": "positive regulation of initiation of acetate catabolic process by acetate", "d": ["Any process that activates or increases the frequency, rate or extent of the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901782", "l": "p-cumate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of p-cumate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044582", "l": "butyryl-CoA catabolic process to butanol", "d": ["The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030715", "l": "oocyte growth in germarium-derived egg chamber", "d": ["The increase in volume of an oocyte during the growth phase of the egg chamber, once the egg chamber has left the germarium. An example of this process is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0000470", "l": "maturation of LSU-rRNA", "d": ["Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003322", "l": "pancreatic A cell development", "d": ["The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0090330", "l": "regulation of platelet aggregation", "d": ["Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009168", "l": "purine ribonucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000044", "l": "negative regulation of cardiac cell fate specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009269", "l": "response to desiccation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016112", "l": "polyterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polyterpenoid compounds, terpenoids with more than eight isoprene units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902160", "l": "negative regulation of cyclic nucleotide-gated ion channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cyclic nucleotide-gated ion channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901591", "l": "regulation of double-strand break repair via break-induced replication", "d": ["Any process that modulates the frequency, rate or extent of double-strand break repair via break-induced replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046392", "l": "galactarate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of galactarate, the anion of galactaric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.207992593949683", "identifiers": [{"i": "GO:0050957", "l": "equilibrioception", "d": ["The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0086054", "l": "bundle of His cell to Purkinje myocyte communication by electrical coupling", "d": ["The process that mediates signaling interactions between a bundle of His cardiac muscle cell and a Purkinje myocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902573", "l": "positive regulation of serine-type peptidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of serine-type peptidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010362", "l": "negative regulation of anion channel activity by blue light", "d": ["Any process in which blue light stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0060439", "l": "trachea morphogenesis", "d": ["The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032000", "l": "positive regulation of fatty acid beta-oxidation", "d": ["Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901126", "l": "candicidin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of candicidin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033133", "l": "positive regulation of glucokinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0007204", "l": "positive regulation of cytosolic calcium ion concentration", "d": ["Any process that increases the concentration of calcium ions in the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016475", "l": "detection of nuclear:cytoplasmic ratio", "d": ["The process in which the size of the nucleus with respect to its cytoplasm is sensed by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0009845", "l": "seed germination", "d": ["The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036216", "l": "cellular response to stem cell factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032025", "l": "response to cobalt ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905510", "l": "negative regulation of myosin II filament assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099531", "l": "presynaptic process involved in chemical synaptic transmission", "d": ["The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0042851", "l": "L-alanine metabolic process", "d": ["The chemical reactions and pathways involving L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901541", "l": "ent-pimara-8(14),15-diene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ent-pimara-8(14),15-diene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010592", "l": "positive regulation of lamellipodium assembly", "d": ["Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "50.791560338470049", "identifiers": [{"i": "GO:0019752", "l": "carboxylic acid metabolic process", "d": ["The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900689", "l": "regulation of gliotoxin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of gliotoxin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014891", "l": "striated muscle atrophy", "d": ["A process, occurring in striated muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060211", "l": "regulation of nuclear-transcribed mRNA poly(A) tail shortening", "d": ["Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001097", "l": "laminaritriose transport", "d": ["The directed movement of a laminaritrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019561", "l": "anaerobic phenylalanine oxidation", "d": ["The chemical reactions and pathways resulting in the breakdown of phenylalanine under anaerobic conditions; occurs via the intermediates phenylpyruvate and phenylacetaldehyde."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015739", "l": "sialic acid transport", "d": ["The directed movement of sialic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080024", "l": "indolebutyric acid metabolic process", "d": ["The chemical reactions and pathways involving indolebutyric acid, a compound that serves as an active or storage form of the hormone indole-3-acetic acid (an auxin) in many plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0061206", "l": "mesonephros morphogenesis", "d": ["The process in which the anatomical structures of the mesonephros are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.053789595961774", "identifiers": [{"i": "GO:0019098", "l": "reproductive behavior", "d": ["The specific behavior of an organism that is associated with reproduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043249", "l": "erythrocyte maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051387", "l": "negative regulation of neurotrophin TRK receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903298", "l": "negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0050792", "l": "regulation of viral process", "d": ["Any process that modulates the rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.194933448780617", "identifiers": [{"i": "GO:0001963", "l": "synaptic transmission, dopaminergic", "d": ["The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000899", "l": "xyloglucan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a xyloglucan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048025", "l": "negative regulation of mRNA splicing, via spliceosome", "d": ["Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900096", "l": "negative regulation of dosage compensation by inactivation of X chromosome", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dosage compensation, by inactivation of X chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035802", "l": "adrenal cortex formation", "d": ["The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031457", "l": "glycine betaine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycine betaine, N-trimethylglycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021862", "l": "early neuron differentiation in forebrain", "d": ["The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of neurons. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.099567117513104", "identifiers": [{"i": "GO:0099587", "l": "inorganic ion import across plasma membrane", "d": ["The directed movement of inorganic ions from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098710", "l": "guanine import across plasma membrane", "d": ["The directed movement of guanine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048894", "l": "efferent axon development in a lateral line nerve", "d": ["The process whose specific outcome is the progression of an efferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in any lateral line nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043107", "l": "type IV pilus-dependent motility", "d": ["Any process involved in the controlled movement of a bacterial cell which is dependent on the presence of type IV pili. Includes social gliding motility and twitching motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072651", "l": "interferon-tau production", "d": ["The appearance of interferon-tau due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090217", "l": "negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity", "d": ["Any process that decreases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2000073", "l": "regulation of cytokinesis, site selection", "d": ["Any process that modulates the frequency, rate or extent of site selection that occurs as part of cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901907", "l": "diadenosine pentaphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diadenosine pentaphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019346", "l": "transsulfuration", "d": ["The interconversion of homocysteine and cysteine via cystathionine. In contrast with enteric bacteria and mammals, Saccharomyces cerevisiae has two transsulfuration pathways employing two separate sets of enzymes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0010922", "l": "positive regulation of phosphatase activity", "d": ["Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0070572", "l": "positive regulation of neuron projection regeneration", "d": ["Any process that activates or increases the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046948", "l": "hydroxylysine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009626", "l": "plant-type hypersensitive response", "d": ["The rapid, localized death of plant cells in response to invasion by a pathogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901925", "l": "negative regulation of protein import into nucleus during spindle assembly checkpoint", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus, and that occurs as a response to the mitotic cell cycle spindle assembly checkpoint. In S. cerevisiae, this process involves inhibition of the karyopherin/importin Kap121p (also known as Pse1p), which acts as the specific nuclear import receptor for several proteins, including Glc7p. Glc7p functions in opposition to key spindle assembly checkpoint protein Aurora kinase (Ipl1p)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140430", "l": "positive regulation of chromosome passenger complex localization to kinetochore", "d": ["Any process that activates or increases the frequency, rate or extent of a chromosome passenger complex localization to kinetochore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905408", "l": "negative regulation of creatine transmembrane transporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of creatine transmembrane transporter activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0045604", "l": "regulation of epidermal cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of epidermal cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061938", "l": "protein localization to somatodendritic compartment", "d": ["A process in which a protein is transported to or maintained in a location within the somatodendritic compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090731", "l": "cellular response to very-low-density lipoprotein particle stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very-low-density lipoprotein particle stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150067", "l": "regulation of tubulin deacetylase activity", "d": ["Any process that modulates the frequency, rate or extent of tubulin deacetylase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018067", "l": "peptidyl-L-3',4'-dihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine", "d": ["The modification of protein tyrosine to peptidyl-L-3',4'-dihydroxyphenylalanine (DOPA)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0022012", "l": "subpallium cell proliferation in forebrain", "d": ["The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034315", "l": "regulation of Arp2/3 complex-mediated actin nucleation", "d": ["Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010653", "l": "negative regulation of cell communication by chemical coupling", "d": ["Any process that decreases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0061462", "l": "protein localization to lysosome", "d": ["A process in which a protein is transported to, or maintained in, a location within a lysosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098746", "l": "fast, calcium ion-dependent exocytosis of neurotransmitter", "d": ["The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006921", "l": "cellular component disassembly involved in execution phase of apoptosis", "d": ["The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0120244", "l": "terminal acetylenic compound metabolic process", "d": ["The chemical reactions and pathways involving a terminal acetylenic compound, involving a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072385", "l": "minus-end-directed organelle transport along microtubule", "d": ["The directed movement of an organelle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0007064", "l": "mitotic sister chromatid cohesion", "d": ["The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.675373588411375", "identifiers": [{"i": "GO:0051302", "l": "regulation of cell division", "d": ["Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904158", "l": "axonemal central apparatus assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an axonemal central apparatus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002355", "l": "detection of tumor cell", "d": ["The series of events in which a stimulus from a tumor cell is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031204", "l": "post-translational protein targeting to membrane, translocation", "d": ["The process in which a protein translocates through the ER membrane posttranslationally."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0071869", "l": "response to catecholamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110062", "l": "negative regulation of angiotensin-activated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the angiotensin-activated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904422", "l": "cellular response to D-galactosamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071338", "l": "positive regulation of hair follicle cell proliferation", "d": ["Any process that activates or increases the rate or extent of hair follicle cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097338", "l": "response to clozapine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0090056", "l": "regulation of chlorophyll metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chlorophyll."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140540", "l": "negative regulation melanotic encapsulation of foreign target", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of melanotic encapsulation of foreign target."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061406", "l": "positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002723", "l": "positive regulation of B cell cytokine production", "d": ["Any process that activates or increases the frequency, rate, or extent of B cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903499", "l": "regulation of mitotic actomyosin contractile ring assembly", "d": ["Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051906", "l": "maintenance of pigment granule location", "d": ["Any process in which a pigment granule is maintained in a location and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0110104", "l": "mRNA alternative polyadenylation", "d": ["The process of generating multiple mRNA molecules with variable 3'-end length formation from a given pre-mRNA by differential use of cleavage and polyadenylation signals (pA signals)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060776", "l": "simple leaf morphogenesis", "d": ["The leaf morphogenesis process which results in the shaping of a simple leaf. A simple leaf is a leaf in which the lamina is undivided."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.897362576241761", "identifiers": [{"i": "GO:0015870", "l": "acetylcholine transport", "d": ["The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905677", "l": "regulation of adaptive immune effector response", "d": ["Any process that modulates the frequency, rate or extent of adaptive immune effector response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0110017", "l": "cap-independent translational initiation of linear mRNA", "d": ["The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0031582", "l": "replication fork arrest at rDNA repeats", "d": ["A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0042427", "l": "serotonin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010764", "l": "negative regulation of fibroblast migration", "d": ["Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045608", "l": "negative regulation of inner ear auditory receptor cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036048", "l": "protein desuccinylation", "d": ["The removal of a succinyl group (CO-CH2-CH2-CO) from a residue in a peptide or protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009937", "l": "regulation of gibberellic acid mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of gibberellic acid mediated signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018930", "l": "3-methylquinoline metabolic process", "d": ["The chemical reactions and pathways involving 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075257", "l": "positive regulation of teliospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903303", "l": "negative regulation of pyruvate kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904393", "l": "regulation of skeletal muscle acetylcholine-gated channel clustering", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150008", "l": "bulk synaptic vesicle endocytosis", "d": ["Endocytosis of large regions of presynaptic membrane after intense stimulation-mediated fusion of multiple synaptic vesicles. Bulk endocytosis is triggered by high loads of membrane addition through exocytosis of synaptic vesicles and elevated concentration of calcium in the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1902299", "l": "pre-replicative complex assembly involved in cell cycle DNA replication", "d": ["Any pre-replicative complex assembly that is involved in cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046201", "l": "cyanate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyanate, NCO-, the anion of cyanic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0050979", "l": "magnetoreception by sensory perception of mechanical stimulus", "d": ["The series of events required for an organism to receive a mechanical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. A magnetic field exerts a torque on a ferromagnetic material (e.g. magnetite) or on a material with diamagnetic anisotropy; organisms that can detect this torque can use it to determine the orientation of the magnetic field."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905701", "l": "positive regulation of xenobiotic detoxification by transmembrane export across the plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010048", "l": "vernalization response", "d": ["The process of thermal induction in plants in which flowering is promoted by exposure to low temperatures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001059", "l": "transcription by RNA polymerase IV", "d": ["The synthesis of RNA from a DNA template by RNA polymerase IV, originating at a Pol IV-specific promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045707", "l": "regulation of adult salivary gland boundary specification", "d": ["Any process that modulates the frequency, rate or extent of salivary gland determination in an adult organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046381", "l": "CMP-N-acetylneuraminate metabolic process", "d": ["The chemical reactions and pathways involving CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070834", "l": "phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine", "d": ["The phosphatidylcholine biosynthetic process that begins with two N-methylations with phospho-base phosphoethanolamine and phospho-N-methylethanolamine, followed by a downstream N-methylation on phosphatidyl-base phosphatidyl-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071865", "l": "regulation of apoptotic process in bone marrow cell", "d": ["Any process that modulates the occurrence or rate of cell death by apoptotic process in the bone marrow."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140084", "l": "sexual macrocyst formation", "d": ["The fusion of haploid amoebae cells with matching mating types to form a larger cell, which ingests additional amoebae and forms a cellulose wall. The resulting macrocyst undergoes recombination and meiosis followed by release of haploid amoebae. An example of this process can be found in Dictyostelium discoideum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032686", "l": "negative regulation of hepatocyte growth factor production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of hepatocyte growth factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042539", "l": "hypotonic salinity response", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904764", "l": "chaperone-mediated autophagy translocation complex disassembly", "d": ["The disaggregation of a chaperone-mediated autophagy translocation complex into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0036119", "l": "response to platelet-derived growth factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0043200", "l": "response to amino acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043363", "l": "nucleate erythrocyte differentiation", "d": ["The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0007124", "l": "pseudohyphal growth", "d": ["The process in which cells grow as a chain of physically attached, elongated cells in response to an environmental stimulus or stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900932", "l": "regulation of nonadec-1-ene metabolic process", "d": ["Any process that modulates the frequency, rate or extent of nonadec-1-ene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1904925", "l": "positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "d": ["Any process that activates or increases the frequency, rate or extent of autophagy of the mitochondrion in response to mitochondrial depolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098969", "l": "neurotransmitter receptor transport to postsynaptic membrane", "d": ["The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015881", "l": "creatine transmembrane transport", "d": ["The directed movement of creatine across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0019413", "l": "acetate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035768", "l": "endothelial cell chemotaxis to fibroblast growth factor", "d": ["The directed movement of an endothelial cell in response to the presence of fibroblast growth factor (FGF)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007505", "l": "adult fat body development", "d": ["The process whose specific outcome is the progression of the adult fat body over time, from its formation to the mature structure. Larval fat body cells that remain at eclosion degenerate in the first 2 to 4 days of adult life, leaving behind the smaller cells of the adult fat body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903584", "l": "regulation of histone deubiquitination", "d": ["Any process that modulates the frequency, rate or extent of histone deubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0046888", "l": "negative regulation of hormone secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000851", "l": "positive regulation of glucocorticoid secretion", "d": ["Any process that activates or increases the frequency, rate or extent of glucocorticoid secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010023", "l": "proanthocyanidin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of proanthocyanidin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0016575", "l": "histone deacetylation", "d": ["The modification of histones by removal of acetyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021897", "l": "forebrain astrocyte development", "d": ["The process aimed at the progression of an astrocyte that resides in the forebrain, from initial commitment of the cell to its fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.523848750789256", "identifiers": [{"i": "GO:0007586", "l": "digestion", "d": ["The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0002702", "l": "positive regulation of production of molecular mediator of immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0010928", "l": "regulation of auxin mediated signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0061245", "l": "establishment or maintenance of bipolar cell polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036495", "l": "negative regulation of translation initiation in response to endoplasmic reticulum stress", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060957", "l": "endocardial cell fate commitment", "d": ["The commitment of a cell to an endocardial cell fate and its capacity to differentiate into an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140281", "l": "positive regulation of mitotic division septum assembly", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0075262", "l": "negative regulation of spore-bearing organ development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044637", "l": "envenomation resulting in negative regulation of complement activation, classical pathway in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of complement activation via the classical pathway of the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060192", "l": "negative regulation of lipase activity", "d": ["Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006048", "l": "UDP-N-acetylglucosamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045002", "l": "double-strand break repair via single-strand annealing", "d": ["Repair of a DSB made between two repeated sequences oriented in the same direction occurs primarily by the single strand annealing pathway. The ends of the break are processed by a 5' to 3' exonuclease, exposing complementary single-strand regions of the direct repeats that can anneal, resulting in a deletion of the unique DNA between the direct repeats."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045854", "l": "positive regulation of bicoid mRNA localization", "d": ["Any process that activates or increases the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009454", "l": "aerotaxis", "d": ["The directed movement of a motile cell or organism in response to environmental oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1990636", "l": "reproductive senescence", "d": ["A life cycle stage during which the reproductive capacity and fitness of an organism declines."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150093", "l": "amyloid-beta clearance by transcytosis", "d": ["The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by transcytosis across the blood-brain barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003041", "l": "excitation of vasomotor center by carotid body chemoreceptor signaling", "d": ["The process in which the molecular signal from a carotid body is relayed to the vasomotor center, causing it to signal an increase arterial pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904113", "l": "negative regulation of muscle filament sliding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of muscle filament sliding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904280", "l": "negative regulation of transcription by RNA polymerase V", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transcription mediated by RNA polymerase V."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061521", "l": "hepatic stellate cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a hepatic stellate cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900339", "l": "regulation of methane biosynthetic process from formic acid", "d": ["Any process that modulates the frequency, rate or extent of methane biosynthetic process from formic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0050773", "l": "regulation of dendrite development", "d": ["Any process that modulates the frequency, rate or extent of dendrite development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900508", "l": "positive regulation of iron-sulfur-molybdenum cofactor assembly", "d": ["Any process that activates or increases the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048851", "l": "hypophysis formation", "d": ["The process in which the anatomical structures of the hypophysis are generated and organized. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071630", "l": "nuclear protein quality control by the ubiquitin-proteasome system", "d": ["The chemical reactions and pathways resulting in the breakdown of misfolded proteins via a mechanism in which the proteins are transported to the nucleus for ubiquitination, and then targeted to proteasomes for degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904657", "l": "negative regulation of sensory perception of sweet taste", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of sweet taste."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901346", "l": "negative regulation of vasculature development involved in avascular cornea development in camera-type eye", "d": ["Any negative regulation of vasculature development that is involved in developing an avascular cornea of a camera-type eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009877", "l": "nodulation", "d": ["The formation of nitrogen-fixing root nodules on plant roots."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0050674", "l": "urothelial cell proliferation", "d": ["The multiplication or reproduction of urothelial cells, resulting in the expansion of a cell population. Urothelial cells make up a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009236", "l": "cobalamin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007307", "l": "eggshell chorion gene amplification", "d": ["Amplification by up to 60-fold of the loci containing the chorion gene clusters. Amplification is necessary for the rapid synthesis of chorion proteins by the follicle cells, and occurs by repeated firing of one or more origins located within each gene cluster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035685", "l": "helper T cell diapedesis", "d": ["The passage of a helper T cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000728", "l": "regulation of mRNA export from nucleus in response to heat stress", "d": ["Any process that modulates the frequency, rate or extent of mRNA export from nucleus in response to heat stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046384", "l": "2-deoxyribose 1-phosphate metabolic process", "d": ["The chemical reactions and pathways involving 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060925", "l": "ventricular cardiac muscle cell fate commitment", "d": ["The commitment of cells to ventricular cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the ventricle. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032655", "l": "regulation of interleukin-12 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-12 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044591", "l": "response to amylopectin", "d": ["A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of amylopectin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900692", "l": "regulation of (+)-kotanin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of (+)-kotanin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098961", "l": "dendritic transport of ribonucleoprotein complex", "d": ["The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150157", "l": "regulation of interleukin-34 production", "d": ["Any process that modulates the frequency, rate or extent of interleukin-34 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903492", "l": "response to acetylsalicylate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aspirin (acetylsalicylate) stimulus. Aspirin is a non-steroidal anti-inflammatory drug with moA cyclooxygenase inhibitor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070416", "l": "trehalose metabolism in response to water deprivation", "d": ["The chemical reactions and pathways involving trehalose that occur as a result of deprivation of water."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098535", "l": "de novo centriole assembly involved in multi-ciliated epithelial cell differentiation", "d": ["Centriole assembly in which a centriole arises de novo by a process involving an electron-dense structure known as a deuterosome, rather than by duplication of an existing centriole, and occurring as part of multi-ciliated epithelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0043939", "l": "negative regulation of sporulation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010980", "l": "positive regulation of vitamin D 24-hydroxylase activity", "d": ["Any process that increases the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905190", "l": "negative regulation of metaphase/anaphase transition of meiosis II", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:1905038", "l": "regulation of membrane lipid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of membrane lipid metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000323", "l": "negative regulation of glucocorticoid receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000279", "l": "negative regulation of DNA biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:1905332", "l": "positive regulation of morphogenesis of an epithelium", "d": ["Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051103", "l": "DNA ligation involved in DNA repair", "d": ["The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:0008361", "l": "regulation of cell size", "d": ["Any process that modulates the size of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0015751", "l": "arabinose transmembrane transport", "d": ["The process in which arabinose, a pentose monosaccharide that occurs in both D and L configurations, is transported across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900618", "l": "regulation of shoot system morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of shoot morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048328", "l": "regulation of axial mesodermal cell fate specification", "d": ["Any process that modulates the frequency, rate or extent of axial mesoderm cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.033057138195133", "identifiers": [{"i": "GO:0018394", "l": "peptidyl-lysine acetylation", "d": ["The acetylation of peptidyl-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033320", "l": "UDP-D-xylose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098506", "l": "polynucleotide 3' dephosphorylation", "d": ["The process of removing one or more phosphate groups from the 3' end of a polynucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071454", "l": "cellular response to anoxia", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000902", "l": "cellooligosaccharide metabolic process", "d": ["The chemical reactions and pathways involving a cellooligosaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0043011", "l": "myeloid dendritic cell differentiation", "d": ["The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090293", "l": "nitrogen catabolite regulation of transcription", "d": ["A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0086048", "l": "membrane depolarization during bundle of His cell action potential", "d": ["The process in which bundle of His cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0034218", "l": "ascospore wall chitin metabolic process", "d": ["The chemical reactions and pathways involving ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071275", "l": "cellular response to aluminum ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0090376", "l": "seed trichome differentiation", "d": ["The process in which a relatively unspecialized epidermal cell acquires the specialized features of a seed trichome. A seed trichome is a trichome that develops from seed coat epidermis and is often long with putative dispersal function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0072319", "l": "vesicle uncoating", "d": ["A protein depolymerization process that results in the disassembly of vesicle coat proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0010660", "l": "regulation of muscle cell apoptotic process", "d": ["Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001287", "l": "negative regulation of caveolin-mediated endocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of caveolin-mediated endocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045234", "l": "protein palmitoleylation", "d": ["The covalent attachment of a palmitoleyl group to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140882", "l": "zinc export across plasma membrane", "d": ["The directed movement of zinc ions from a cell, into the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046511", "l": "sphinganine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sphinganine, D-erythro-2-amino-1,3-octadecanediol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.05504842691775", "identifiers": [{"i": "GO:0006885", "l": "regulation of pH", "d": ["Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090551", "l": "response to manganese starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of manganese."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061370", "l": "testosterone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0097368", "l": "establishment of Sertoli cell barrier", "d": ["Establishment of a structure near the basement membrane in adjacent Sertoli cells of the seminiferous epithelium for maintaining spermatogenesis. The structure consists of tight junctions, basal ectoplasmic specializations, and desmosome-like junctions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019265", "l": "glycine biosynthetic process, by transamination of glyoxylate", "d": ["The chemical reactions and pathways resulting in the formation of glycine by the transamination of glyoxylate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060340", "l": "positive regulation of type I interferon-mediated signaling pathway", "d": ["Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902211", "l": "regulation of prolactin signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of prolactin signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106045", "l": "guanine deglycation, methylglyoxal removal", "d": ["The removal of methylglyoxal from a glycated guanine, to form lactate and a deglycated guanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043506", "l": "regulation of JUN kinase activity", "d": ["Any process that modulates the frequency, rate or extent of JUN kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902039", "l": "negative regulation of seed dormancy process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of seed dormancy process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "53.616589669778747", "identifiers": [{"i": "GO:0007585", "l": "respiratory gaseous exchange by respiratory system", "d": ["The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0043525", "l": "positive regulation of neuron apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010654", "l": "apical cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into an apical cell. The apical cell is the upper cell formed after the first division of the zygote."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043123", "l": "positive regulation of I-kappaB kinase/NF-kappaB signaling", "d": ["Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007225", "l": "patched ligand maturation", "d": ["The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0045026", "l": "plasma membrane fusion", "d": ["The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0055081", "l": "monoatomic anion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of monoatomic anions within an organism or cell. Monatomic anions (also called simple anions) are anions consisting of exactly one atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044506", "l": "modulation of glucagon-like peptide receptor 1 activity in another organism", "d": ["The process in which an organism effects a change in the activity of a glucagon-like peptide receptor 1 in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140367", "l": "antibacterial innate immune response", "d": ["An defense response against a bacteria mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001092", "l": "arabinotriose transport", "d": ["The directed movement of an arabinotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900764", "l": "emericellin metabolic process", "d": ["The chemical reactions and pathways involving emericellin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009836", "l": "fruit ripening, climacteric", "d": ["A fruit ripening process that involves a burst of respiration and ethylene (ethene) evolution at the onset."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018915", "l": "ethylbenzene metabolic process", "d": ["The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring. It is a colorless liquid with a pungent odor used as a solvent and as a component of automotive and aviation fuels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0039017", "l": "pattern specification involved in pronephros development", "d": ["Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0003390", "l": "dendrite development by retrograde extension", "d": ["The progression of a dendrite over time by the attachment of a part of the neuron to an anchor and the subsequent migration of the cell body away from the anchor point."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.468544520863134", "identifiers": [{"i": "GO:0042762", "l": "regulation of sulfur metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031656", "l": "positive regulation of heat dissipation", "d": ["Any process that activates or increases the rate or extent of heat dissipation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0030978", "l": "alpha-glucan metabolic process", "d": ["The chemical reactions and pathways involving alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0072033", "l": "renal vesicle formation", "d": ["The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901410", "l": "regulation of tetrapyrrole biosynthetic process from glutamate", "d": ["Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0060245", "l": "detection of cell density", "d": ["The series of events in which information about the density of cells in a population is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000616", "l": "negative regulation of histone H3-K9 acetylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019262", "l": "N-acetylneuraminate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0019068", "l": "virion assembly", "d": ["A late phase of the viral life cycle during which all the components necessary for the formation of a mature virion collect at a particular site in the cell and the basic structure of the virus particle is formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0046865", "l": "terpenoid transport", "d": ["The directed movement of terpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Terpenoids are a class of compounds characterized by an isoprenoid chemical structure and include derivatives with various functional groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0010171", "l": "body morphogenesis", "d": ["The process in which the anatomical structures of the soma are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002942", "l": "tRNA m2,2-guanine biosynthesis", "d": ["The process whereby a guanine residue in a transfer RNA is methylated twice at the N2 position."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120290", "l": "stalled replication fork localization to nuclear periphery", "d": ["A cellular localization process where a DNA replication fork that has stalled is signaled to relocate and anchor to the nuclear periphery for the time necessary to complete recombination-dependent replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903619", "l": "negative regulation of transdifferentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transdifferentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090249", "l": "regulation of cell migration involved in somitogenic axis elongation", "d": ["Any process that modulates the frequency, rate, or extent of the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0097638", "l": "L-arginine import across plasma membrane", "d": ["The directed movement of L-arginine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901582", "l": "positive regulation of telomeric RNA transcription from RNA pol II promoter", "d": ["Any process that activates or increases the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046417", "l": "chorismate metabolic process", "d": ["The chemical reactions and pathways involving chorismate, the anion of (3R-trans)-3-((1-carboxyethenyl)oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903672", "l": "positive regulation of sprouting angiogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of sprouting angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902195", "l": "isovaleryl-CoA(4-) metabolic process", "d": ["The chemical reactions and pathways involving isovaleryl-CoA(4-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0086044", "l": "atrial cardiac muscle cell to AV node cell communication by electrical coupling", "d": ["The process that mediates signaling interactions between an atrial cardiomyocyte and an AV node cell by transfer of current between their adjacent cytoplasms via intercellular protein channels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0099525", "l": "presynaptic dense core vesicle exocytosis", "d": ["The secretion of molecules (e.g. neuropeptides and neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense in response to increased presynaptic cytosolic calcium levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021632", "l": "optic nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006784", "l": "heme A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heme A, a derivative of heme found in cytochrome aa3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900552", "l": "asperfuranone metabolic process", "d": ["The chemical reactions and pathways involving asperfuranone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032062", "l": "positive regulation of translation in response to osmotic stress", "d": ["Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035311", "l": "wing cell fate specification", "d": ["The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a wing cell, if left in its normal environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.235181147905195", "identifiers": [{"i": "GO:0019230", "l": "proprioception", "d": ["The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1905935", "l": "positive regulation of cell fate determination", "d": ["Any process that activates or increases the frequency, rate or extent of cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042399", "l": "ectoine metabolic process", "d": ["The chemical reactions and pathways involving ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018167", "l": "protein-phycoerythrobilin linkage via phycoerythrobilin-bis-L-cysteine", "d": ["The linkage of the chromophore phycoerythrobilin to phycoerythrin via phycoerythrobilin-bis-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0015766", "l": "disaccharide transport", "d": ["The directed movement of disaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Disaccharides are sugars composed of two monosaccharide units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903620", "l": "positive regulation of transdifferentiation", "d": ["Any process that activates or increases the frequency, rate or extent of transdifferentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.686661695795102", "identifiers": [{"i": "GO:0031175", "l": "neuron projection development", "d": ["The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000014", "l": "regulation of endosperm development", "d": ["Any process that modulates the frequency, rate or extent of endosperm development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072021", "l": "ascending thin limb development", "d": ["The process whose specific outcome is the progression of an ascending thin limb over time, from its formation to the mature structure. The ascending thin limb is a segment of a nephron tubule lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072307", "l": "regulation of metanephric nephron tubule epithelial cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033482", "l": "D-galacturonate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035205", "l": "positive regulation of lamellocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0021554", "l": "optic nerve development", "d": ["The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1990755", "l": "mitotic spindle microtubule depolymerization", "d": ["The removal of tubulin heterodimers from one or both ends of a microtubule that is part of the mitotic spindle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0150107", "l": "positive regulation of protein localization to cell-cell junction", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:1905144", "l": "response to acetylcholine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021630", "l": "olfactory nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904070", "l": "ascaroside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ascaroside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022004", "l": "midbrain-hindbrain boundary maturation during brain development", "d": ["A developmental process occurring after the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0032878", "l": "regulation of establishment or maintenance of cell polarity", "d": ["Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0003422", "l": "growth plate cartilage morphogenesis", "d": ["The process in which the anatomical structures of growth plate cartilage are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045570", "l": "regulation of imaginal disc growth", "d": ["Any process that modulates the frequency, rate or extent of the growth of the imaginal disc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0120275", "l": "cerebral blood circulation", "d": ["The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070629", "l": "(1->4)-alpha-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0042321", "l": "negative regulation of circadian sleep/wake cycle, sleep", "d": ["Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0071634", "l": "regulation of transforming growth factor beta production", "d": ["Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0006086", "l": "acetyl-CoA biosynthetic process from pyruvate", "d": ["The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052482", "l": "defense response by cell wall thickening", "d": ["A type of cell wall modification, in which the cell wall is reinforced and made thicker, that occurs as part of the defense response of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0031321", "l": "ascospore-type prospore assembly", "d": ["During ascospore formation, the process in which each haploid nucleus becomes encapsulated by a double membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990110", "l": "callus formation", "d": ["The process by which a callus is formed at a wound site. A plant callus is a portion of plant tissue that consists of mass of undifferentiated plant cells. It consists primarily of parenchyma cells but possibly contains other cell types as the callus begins to differentiate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0015891", "l": "siderophore transport", "d": ["The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1904526", "l": "regulation of microtubule binding", "d": ["Any process that modulates the frequency, rate or extent of microtubule binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1990045", "l": "sclerotium development", "d": ["The process whose specific outcome is the progression of the sclerotium over time, from its formation to the mature structure. A sclerotium is a mycelial resting body, resistant to adverse environmental conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060450", "l": "positive regulation of hindgut contraction", "d": ["Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "51.237159582972339", "identifiers": [{"i": "GO:0044085", "l": "cellular component biogenesis", "d": ["A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990558", "l": "mitochondrial malonate(1-) transmembrane transport", "d": ["The process in which malonate(1-) is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900982", "l": "positive regulation of phenazine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of phenazine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0032496", "l": "response to lipopolysaccharide", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030576", "l": "Cajal body organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Cajal bodies, nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046672", "l": "positive regulation of compound eye retinal cell programmed cell death", "d": ["Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904516", "l": "myofibroblast cell apoptotic process", "d": ["Any apoptotic process in a myofibroblast cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0034728", "l": "nucleosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904651", "l": "positive regulation of fat cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006098", "l": "pentose-phosphate shunt", "d": ["The metabolic process in which glucose-6-phosphate is oxidized to form carbon dioxide (CO2) and ribulose 5-phosphate, coupled to reduction of NADP+ to NADPH; ribulose 5-P then enters a series of reactions that can yield biosynthetic precursors (ribose-5-phosphate and erythrose-4-phosphate) and glycolytic intermediates (fructose-6-phosphate and glyceraldehyde-3-phosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0072666", "l": "establishment of protein localization to vacuole", "d": ["The directed movement of a protein to a specific location in a vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0106349", "l": "snRNA methylation", "d": ["The posttranscriptional addition of methyl groups to specific residues in an snRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007434", "l": "adult salivary gland boundary specification", "d": ["Determination in an adult organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905052", "l": "negative regulation of base-excision repair", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of base-excision repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030263", "l": "apoptotic chromosome condensation", "d": ["The compaction of chromatin during apoptosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009051", "l": "pentose-phosphate shunt, oxidative branch", "d": ["The branch of the pentose-phosphate shunt which involves the oxidation of glucose 6-P and produces ribulose 5-P, reduced NADP+ and carbon dioxide (CO2)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018908", "l": "organosulfide cycle", "d": ["A cyclic series of interconversions involving dimethyl sulfide, methanethiol and hydrogen sulfide. Dimethylsulfoxide can also be converted to dimethyl sulfide, which enters the cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.780700721499244", "identifiers": [{"i": "GO:0097485", "l": "neuron projection guidance", "d": ["The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044382", "l": "CLRC complex localization to heterochromatin", "d": ["The process by which a CLRC complex is transported to, or maintained in, heterochromatin. CLRC complex is an active cullin-dependent E3 ubiquitin ligase complex essential for heterochromatin assembly by RNAi and histone H3K9 methylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035502", "l": "metanephric part of ureteric bud development", "d": ["The development of the portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061648", "l": "tooth replacement", "d": ["The process whose specific outcome is the replacement of an existing tooth with another tooth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048780", "l": "positive regulation of erythrophore differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of erythrophore differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000293", "l": "negative regulation of defecation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of defecation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0010233", "l": "phloem transport", "d": ["The directed movement of substances, into, out of or within the phloem during long distance transport between source and sink tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902161", "l": "positive regulation of cyclic nucleotide-gated ion channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of cyclic nucleotide-gated ion channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048091", "l": "positive regulation of female pigmentation", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in females."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010338", "l": "leaf formation", "d": ["The process that gives rise to a leaf. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099561", "l": "synaptic membrane adhesion to extracellular matrix", "d": ["The binding of a synaptic membrane to the extracellular matrix via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042370", "l": "thiamine diphosphate dephosphorylation", "d": ["The removal of one or more phosphate groups from thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903868", "l": "regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity", "d": ["Any process that modulates the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090675", "l": "intermicrovillar adhesion", "d": ["The cell-cell adhesion process by which adjacent microvilli attach to each other through Ca(2+)-dependent adhesion links made of protocadherin-24 and mucin-like protocadherin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0001675", "l": "acrosome assembly", "d": ["The formation of the acrosome from the spermatid Golgi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141018", "l": "adhesion of symbiont to host via host extracellular matrix", "d": ["The attachment of a symbiont to its host by binding to a component of the host extracellular matrix. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0097475", "l": "motor neuron migration", "d": ["The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0002347", "l": "response to tumor cell", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0002661", "l": "regulation of B cell tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of B cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902895", "l": "positive regulation of miRNA transcription", "d": ["Any process that activates or increases the frequency, rate or extent of microRNA (miRNA) gene transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051678", "l": "pullulan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061554", "l": "ganglion formation", "d": ["The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903049", "l": "negative regulation of acetylcholine-gated cation channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine-gated cation channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0002401", "l": "tolerance induction in mucosal-associated lymphoid tissue", "d": ["Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071165", "l": "GINS complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a GINS complex, a heterotetrameric protein complex that associates with DNA replication origins and replication forks."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072094", "l": "metanephric renal vesicle induction", "d": ["Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the metanephric renal vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060867", "l": "fruit abscission", "d": ["The controlled shedding of a fruit."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007355", "l": "anterior region determination", "d": ["Specification of the anterior (head and thoracic segments) of the embryo by the gap genes; exemplified in insects by the actions of hunchback gene product."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031506", "l": "cell wall glycoprotein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cell wall glycoproteins, any cell wall protein that contains covalently bound sugar residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0031106", "l": "septin ring organization", "d": ["Control of the formation, spatial distribution, and breakdown of the septin ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "48.79739920206562", "identifiers": [{"i": "GO:0033036", "l": "macromolecule localization", "d": ["Any process in which a macromolecule is transported to, or maintained in, a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046289", "l": "isoflavonoid phytoalexin metabolic process", "d": ["The chemical reactions and pathways involving isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905460", "l": "negative regulation of vascular associated smooth muscle cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061819", "l": "telomeric DNA-containing double minutes formation", "d": ["A telomere maintenance process that results in the formation of small fragments of circular extrachromosomal DNA elements which contain telomeric DNA. It is speculated that telomeric DNA-containing double minutes are formed through a recombination event between the telomere and chromosome-internal TTAGGG-like sequences. Telomeric DNA-containing double minutes appear as two closely positioned dots in metaphase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903094", "l": "negative regulation of protein K48-linked deubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein K48-linked deubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002550", "l": "positive regulation of plasma kallikrein-kinin cascade", "d": ["Any process that activates or increases the frequency, rate, or extent of the plasma kallikrein-kinin cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904679", "l": "myo-inositol import across plasma membrane", "d": ["The directed movement of myo-inositol from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072162", "l": "metanephric mesenchymal cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001028", "l": "positive regulation of endothelial cell chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072745", "l": "cellular response to antimycin A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0008593", "l": "regulation of Notch signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the Notch signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901287", "l": "iron-sulfur-molybdenum cofactor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of iron-sulfur-molybdenum cofactor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045312", "l": "nor-spermidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010522", "l": "regulation of calcium ion transport into cytosol", "d": ["Any process that modulates the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0009084", "l": "glutamine family amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060690", "l": "epithelial cell differentiation involved in salivary gland development", "d": ["The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010136", "l": "ureide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ureide, which is the organic form of nitrogen in nitrogen fixing and transporting plants with the release of ammonium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071602", "l": "phytosphingosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072292", "l": "epithelial cell migration involved in metanephric proximal tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to metanephric proximal tubule morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902768", "l": "isoprenoid biosynthetic process via 1-deoxy-D-xylulose 5-phosphate", "d": ["The chemical reactions and pathways resulting in the formation of isoprenoid via 1-deoxy-D-xylulose 5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904743", "l": "negative regulation of telomeric DNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomeric DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0006750", "l": "glutathione biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0097581", "l": "lamellipodium organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. A lamellipodium is a thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0097284", "l": "hepatocyte apoptotic process", "d": ["Any apoptotic process in a hepatocyte, the main structural component of the liver."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043366", "l": "beta selection", "d": ["The process in which successful recombination of a T cell receptor beta chain into a translatable protein coding sequence leads to rescue from apoptosis and subsequent proliferation of an immature T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098920", "l": "retrograde trans-synaptic signaling by lipid", "d": ["Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.461014234140904", "identifiers": [{"i": "GO:0048534", "l": "hematopoietic or lymphoid organ development", "d": ["The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1903830", "l": "magnesium ion transmembrane transport", "d": ["The directed movement of magnesium ion across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014727", "l": "positive regulation of extraocular skeletal muscle development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990762", "l": "cytoplasmic alanyl-tRNA aminoacylation", "d": ["The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase involved in cytoplasmic translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002546", "l": "negative regulation of tissue kallikrein-kinin cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the tissue kallikrein-kinin cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.651613913496419", "identifiers": [{"i": "GO:0045637", "l": "regulation of myeloid cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of myeloid cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0043484", "l": "regulation of RNA splicing", "d": ["Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0032206", "l": "positive regulation of telomere maintenance", "d": ["Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0014742", "l": "positive regulation of muscle hypertrophy", "d": ["Any process that activates or increases the frequency, rate or extent of muscle hypertrophy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0060433", "l": "bronchus development", "d": ["The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070790", "l": "phialide development", "d": ["The process whose specific outcome is the progression of phialides over time, from its formation to the mature structure. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. Chains of conidia, or asexual spores, develop from the phialide tips."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061015", "l": "snRNA import into nucleus", "d": ["The directed movement of snRNA, small nuclear ribonucleic acid into the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048549", "l": "positive regulation of pinocytosis", "d": ["Any process that activates, maintains or increases the rate of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001120", "l": "methanofuran biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a methanofuran."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110034", "l": "negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106289", "l": "negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070212", "l": "protein poly-ADP-ribosylation", "d": ["The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.232064878529073", "identifiers": [{"i": "GO:0051231", "l": "spindle elongation", "d": ["The cell cycle process in which the distance is lengthened between poles of the spindle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900457", "l": "regulation of brassinosteroid mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of brassinosteroid mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061873", "l": "regulation of hepatic stellate cell contraction", "d": ["Any process that modulates the frequency, rate or extent of hepatic stellate cell contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900711", "l": "negative regulation of tensidol B biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tensidol B biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062248", "l": "cleistothecium formation", "d": ["The process of producing a cleistothecium, a closed sexual fruiting body that contains ascospores in linear asci. Cleistothecia are present in some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035227", "l": "regulation of glutamate-cysteine ligase activity", "d": ["Any process that modulates the activity of glutamate-cysteine ligase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.444551060876734", "identifiers": [{"i": "GO:0043549", "l": "regulation of kinase activity", "d": ["Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.850028330009977", "identifiers": [{"i": "GO:0007622", "l": "rhythmic behavior", "d": ["The specific behavior of an organism that recur with measured regularity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043973", "l": "histone H3-K4 acetylation", "d": ["The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 4 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019240", "l": "citrulline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071938", "l": "vitamin A transport", "d": ["The directed movement any form of vitamin A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904484", "l": "cloacal gland development", "d": ["The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900827", "l": "positive regulation of membrane depolarization during cardiac muscle cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140979", "l": "intracellular nucleotide homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of nucleotides within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905743", "l": "calcium import into the mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration", "d": ["Any mitochondrial calcium uptake that is involved in negative regulation of presynaptic cytosolic calcium concentration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905775", "l": "negative regulation of DNA helicase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent DNA helicase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0072124", "l": "regulation of glomerular mesangial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of glomerular mesangial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051522", "l": "activation of monopolar cell growth", "d": ["Any process that initiates the inactive process of monopolar cell growth, polarized growth from one end of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0061077", "l": "chaperone-mediated protein folding", "d": ["The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120198", "l": "positive regulation of imaginal disc-derived wing size", "d": ["Any process that increases the size of an imaginal disc-derived wing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043042", "l": "amino acid adenylylation by nonribosomal peptide synthase", "d": ["Activation of an amino acid for incorporation into a peptide by a nonribosomal process, catalyzed by subunits of nonribosomal peptide synthase. The amino acid is adenylated at its carboxylate group (ATP-dependent) then transferred to the thiol group of an enzyme-bound phosphopantetheine cofactor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000629", "l": "negative regulation of miRNA metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of miRNA metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008153", "l": "para-aminobenzoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097330", "l": "response to 5-fluoro-2'-deoxyuridine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluoro-2'-deoxyuridine stimulus. 5-fluoro-2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; it is used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031556", "l": "transcriptional attenuation by ribosome", "d": ["A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106028", "l": "neuron projection retraction", "d": ["The organization process which results in the disassembly (either partial or complete) of constituent parts of a neuron projection. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061207", "l": "mesonephric juxtaglomerulus cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the mesonephros as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900869", "l": "tatiopterin metabolic process", "d": ["The chemical reactions and pathways involving tatiopterin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900290", "l": "positive regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0031343", "l": "positive regulation of cell killing", "d": ["Any process that activates or increases the frequency, rate or extent of cell killing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046079", "l": "dUMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dUMP, deoxyuridine (5'-)monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039560", "l": "disruption by virus of host JAK-STAT cascade via inhibition of host IRF9 activity", "d": ["Any process in which a virus interferes with a JAK1-STAT signaling cascade in a host organism by reducing the activity of host IRF9 (interferon regulatory factor-9), a transcription factor involved in the innate immune response. Viral infection triggers binding of IRF9 to phosphorylated STAT1 and STAT2, forming the ISGF3 complex. The ISGF3 complex migrates to the nucleus and activates transcription of IFN-responsive genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022000", "l": "forebrain induction by the anterior neural ridge", "d": ["The close range interaction of the anterior neural ridge to the caudal region of the neural plate that specifies the forebrain fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0052165", "l": "symbiont defense to host-produced phytoalexin", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001811", "l": "negative regulation of type I hypersensitivity", "d": ["Any process that stops, prevents, or reduces the rate of type I hypersensitivity, a type of inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900273", "l": "positive regulation of long-term synaptic potentiation", "d": ["Any process that activates or increases the frequency, rate or extent of long-term synaptic potentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071035", "l": "nuclear polyadenylation-dependent rRNA catabolic process", "d": ["The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, including RNA fragments released as part of processing the primary transcript into multiple mature rRNA species, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072042", "l": "regulation of mesenchymal stem cell proliferation involved in nephron morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation and contributes to the shaping of a nephron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021821", "l": "negative regulation of cell-glial cell adhesion involved in cerebral cortex lamination", "d": ["The process that results in the release of migrating cells from their interaction with radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050696", "l": "trichloroethylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905175", "l": "negative regulation of vascular associated smooth muscle cell dedifferentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell dedifferentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0072283", "l": "metanephric renal vesicle morphogenesis", "d": ["The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904010", "l": "response to Aroclor 1254", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905676", "l": "positive regulation of adaptive immune memory response", "d": ["Any process that activates or increases the frequency, rate or extent of adaptive immune memory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018103", "l": "protein C-linked glycosylation", "d": ["A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a C atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106398", "l": "negative regulation of R7 cell fate commitment", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of R7 cell fate commitment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033470", "l": "gibberellin 12 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1900407", "l": "regulation of cellular response to oxidative stress", "d": ["Any process that modulates the frequency, rate or extent of cellular response to oxidative stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001214", "l": "positive regulation of vasculogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of vasculogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.664775500092716", "identifiers": [{"i": "GO:0034293", "l": "sexual sporulation", "d": ["The formation of spores derived from the products of meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.161881760686384", "identifiers": [{"i": "GO:0007052", "l": "mitotic spindle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0051797", "l": "regulation of hair follicle development", "d": ["Any process that modulates the frequency, rate or extent of hair follicle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075224", "l": "positive regulation of sporangium germination", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of sporangium germination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019330", "l": "aldoxime metabolic process", "d": ["The chemical reactions and pathways involving aldoximes, compounds derived by the reaction of an aldose with hydroxylamine, thus containing the aldoxime group -HC=NOH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0150011", "l": "regulation of neuron projection arborization", "d": ["Any process that modulates the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043480", "l": "pigment accumulation in tissues", "d": ["The aggregation of coloring matter in a particular location in a tissue, occurring in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0035444", "l": "nickel cation transmembrane transport", "d": ["The directed movement of nickel (Ni) cations across a membrane by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070845", "l": "polyubiquitinated misfolded protein transport", "d": ["The directed movement of misfolded polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045654", "l": "positive regulation of megakaryocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903744", "l": "positive regulation of anterograde synaptic vesicle transport", "d": ["Any process that activates or increases the frequency, rate or extent of anterograde synaptic vesicle transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046157", "l": "siroheme catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009714", "l": "chalcone metabolic process", "d": ["The chemical reactions and pathways involving chalcones, phenyl steryl ketone or its hydroxylated derivatives."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018317", "l": "protein C-linked glycosylation via tryptophan", "d": ["The glycosylation of a carbon atom of a peptidyl-tryptophan residue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003396", "l": "cell adhesion involved in amphid sensory organ dendrite retrograde extension", "d": ["The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite in a neuron of the amphid sensory organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0034775", "l": "glutathione transmembrane transport", "d": ["A process in which glutathione is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036034", "l": "mediator complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046775", "l": "suppression by virus of host cytokine production", "d": ["Any viral process that results in the inhibition of host cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0001707", "l": "mesoderm formation", "d": ["The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051221", "l": "tungsten incorporation into metallo-sulfur cluster", "d": ["The incorporation of tungsten into a metallo-sulfur cluster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090263", "l": "positive regulation of canonical Wnt signaling pathway", "d": ["Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:0050767", "l": "regulation of neurogenesis", "d": ["Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0006084", "l": "acetyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061941", "l": "positive regulation of c-di-GMP signaling", "d": ["Any process that increases the rate, frequency or extent of c-di-GMP signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032402", "l": "melanosome transport", "d": ["The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904219", "l": "positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.879406879579491", "identifiers": [{"i": "GO:0043068", "l": "positive regulation of programmed cell death", "d": ["Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902221", "l": "erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process", "d": ["The chemical reactions and pathways involving erythrose 4-phosphate/phosphoenolpyruvate family amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000494", "l": "box C/D RNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a box C/D RNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030631", "l": "pyrrolysine incorporation", "d": ["The incorporation of pyrrolysine, also known as lysine methylamine methyltransferase cofactor adduct, into a peptide; uses a special tRNA that recognizes the UAG codon as a modified lysine, rather than as a termination codon. Pyrrolysine may be synthesized as a free amino acid or synthesized from a lysine charged tRNA before its incorporation; it is not a posttranslational modification of peptidyl-lysine; this modification is found in several Methanosarcina methylamine methyltransferases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010495", "l": "siRNA-mediated long-distance post-transcriptional gene silencing", "d": ["An siRNA-mediated posttranscriptional gene silencing pathway in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs, and in which the silencing signal originates in one tissue and occurs in a different tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071140", "l": "resolution of mitotic recombination intermediates", "d": ["The cleavage and rejoining of intermediates, mitotic recombination to produce two intact molecules in which genetic material has been exchanged."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0051934", "l": "catecholamine uptake involved in synaptic transmission", "d": ["The uptake of catecholamine neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071810", "l": "regulation of fever generation by regulation of prostaglandin secretion", "d": ["Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000764", "l": "positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900699", "l": "negative regulation of o-orsellinic acid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of o-orsellinic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140782", "l": "novofumigatonin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of novofumigatonin, a heavily oxygenated meroterpenoid containing a unique orthoester moiety."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019279", "l": "L-methionine biosynthetic process from L-homoserine via cystathionine", "d": ["The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including L-homoserine, via the intermediate cystathionine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0033060", "l": "ocellus pigmentation", "d": ["The deposition or aggregation of coloring matter in an ocellus, a minute simple eye found in many invertebrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0045191", "l": "regulation of isotype switching", "d": ["Any process that modulates the frequency, rate or extent of isotype switching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021702", "l": "cerebellar Purkinje cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018905", "l": "dimethyl ether metabolic process", "d": ["The chemical reactions and pathways involving dimethyl ether, CH3-O-CH3, the simplest ether. Dimethyl ether, also known wood ether and methyl ether, is a colorless gas that has been used in refrigeration applications."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.819490397197882", "identifiers": [{"i": "GO:0030879", "l": "mammary gland development", "d": ["The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070709", "l": "RNA guanosine insertion", "d": ["The modification of an RNA molecule by insertion of a guanosine nucleotide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0000724", "l": "double-strand break repair via homologous recombination", "d": ["The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902042", "l": "negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070175", "l": "positive regulation of enamel mineralization", "d": ["Any process that activates or increases the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036270", "l": "response to diuretic", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diuretic stimulus. A diuretic is an agent that promotes the excretion of urine through its effects on kidney function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048817", "l": "negative regulation of hair follicle maturation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904513", "l": "negative regulation of initiation of premeiotic DNA replication", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of initiation of premeiotic DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "34.860072584558765", "identifiers": [{"i": "GO:0007154", "l": "cell communication", "d": ["Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061848", "l": "cellular response to cholecystokinin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.116918913335823", "identifiers": [{"i": "GO:0032104", "l": "regulation of response to extracellular stimulus", "d": ["Any process that modulates the frequency, rate or extent of a response to an extracellular stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900737", "l": "negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0034609", "l": "spicule insertion", "d": ["Insertion of the male copulatory spicules into the hermaphrodite. Spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901866", "l": "capsorubin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of capsorubin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044551", "l": "envenomation resulting in vasodilation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant vasodilation of blood vessels, usually causing a reduction in blood pressure, in the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097104", "l": "postsynaptic membrane assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0042401", "l": "biogenic amine biosynthetic process", "d": ["The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110056", "l": "positive regulation of actin filament annealing", "d": ["Any process that activates or increases the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0045610", "l": "regulation of hemocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of hemocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0052155", "l": "modulation by symbiont of host cell-mediated immune response", "d": ["Any process in which an organism modulates the frequency, rate or extent of any form of cell-based immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902234", "l": "positive regulation of positive thymic T cell selection", "d": ["Any process that activates or increases the frequency, rate or extent of positive thymic T cell selection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0045841", "l": "negative regulation of mitotic metaphase/anaphase transition", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070277", "l": "iodide oxidation", "d": ["The chemical reactions and pathways by which iodide is converted to diiodine, with the concomitant loss of electrons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150152", "l": "negative regulation of interleukin-17A production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17A production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900850", "l": "negative regulation of pseurotin A biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pseurotin A biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006214", "l": "thymidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0032383", "l": "regulation of intracellular cholesterol transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901259", "l": "chloroplast rRNA processing", "d": ["Any rRNA processing that takes place in chloroplast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033147", "l": "negative regulation of intracellular estrogen receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990669", "l": "endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with endoplasmic reticulum membrane", "d": ["The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane of the ER. Such vesicles include COPI-coated transport vesicles involved in retrograde transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003344", "l": "pericardium morphogenesis", "d": ["The process in which the anatomical structure of the pericardium is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097681", "l": "double-strand break repair via alternative nonhomologous end joining", "d": ["An instance of double-strand break repair via nonhomologous end joining that is independent of factors important for V(D)J recombination (as opposed to classical nonhomologous end joining). It often results in a deletion with microhomology (i.e. 5-25bp homology) at the repair junction. Among different subclasses of nonhomologous end joining (NHEJ), alternative NHEJ appears to play a significant role in the etiology of mutations that arise during cancer development and treatment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048922", "l": "posterior lateral line neuromast deposition", "d": ["The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072290", "l": "epithelial cell migration involved in metanephric nephron tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061794", "l": "conidium development", "d": ["The process whose specific outcome is the progression of conidium over time, from its formation to the mature structure. Conidia are non-motile spores produced via mitotic asexual reproduction in higher fungi; they are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.741834732726957", "identifiers": [{"i": "GO:0046395", "l": "carboxylic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002798", "l": "negative regulation of antibacterial peptide secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140124", "l": "positive regulation of Lewy body formation", "d": ["Any process that activates or increases the frequency, rate or extent of Lewy body formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904799", "l": "regulation of neuron remodeling", "d": ["Any process that modulates the frequency, rate or extent of neuron remodeling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002621", "l": "positive regulation of non-professional antigen presenting cell antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0051318", "l": "G1 phase", "d": ["The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019528", "l": "D-arabitol catabolic process to xylulose 5-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of D-arabitol to form xylulose 5-phosphate. D-arabitol is converted into D-xylulose, which is then phosphorylated to form D-xylulose-5-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110064", "l": "lncRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lncRNAs, non-coding RNAs over 200 nucleotides in length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048688", "l": "negative regulation of sprouting of injured axon", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sprouting of an injured axon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0002701", "l": "negative regulation of production of molecular mediator of immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070125", "l": "mitochondrial translational elongation", "d": ["The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035426", "l": "extracellular matrix-cell signaling", "d": ["Any process that mediates the transfer of information between the extracellular matrix and a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006070", "l": "octanol metabolic process", "d": ["The chemical reactions and pathways involving octanol, the 8-carbon alcohol with the formula C8H17OH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0010508", "l": "positive regulation of autophagy", "d": ["Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:1905475", "l": "regulation of protein localization to membrane", "d": ["Any process that modulates the frequency, rate or extent of protein localization to membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903067", "l": "negative regulation of protein localization to cell tip", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000810", "l": "regulation of bicellular tight junction assembly", "d": ["Any process that modulates the frequency, rate or extent of tight junction assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070152", "l": "mitochondrial isoleucyl-tRNA aminoacylation", "d": ["The process of coupling isoleucine to isoleucyl-tRNA in a mitochondrion, catalyzed by isoleucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900383", "l": "regulation of synaptic plasticity by receptor localization to synapse", "d": ["Any process that modulates synaptic plasticity, the ability of synapses to change as circumstances require, via receptor localization to the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. Processes may include receptor transport to, and/or maintenance at, the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903330", "l": "negative regulation of iron-sulfur cluster assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur cluster assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010228", "l": "vegetative to reproductive phase transition of meristem", "d": ["The process involved in transforming a meristem that produces vegetative structures, such as leaves, into a meristem that produces reproductive structures, such as a flower or an inflorescence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901341", "l": "positive regulation of store-operated calcium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of store-operated calcium channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900832", "l": "D-leucine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-leucine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160058", "l": "plant endodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a plant endodermal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904619", "l": "response to dimethyl sulfoxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904669", "l": "ATP export", "d": ["The directed movement of ATP out of a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.968459345787338", "identifiers": [{"i": "GO:1905953", "l": "negative regulation of lipid localization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009223", "l": "pyrimidine deoxyribonucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045571", "l": "negative regulation of imaginal disc growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048330", "l": "positive regulation of axial mesodermal cell fate specification", "d": ["Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0072311", "l": "glomerular epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015726", "l": "L-idonate transmembrane transport", "d": ["The process in which L-idonate is transported across a lipid bilayer, from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905265", "l": "blasticidin S catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of blasticidin S."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099087", "l": "anterograde axonal transport of messenger ribonucleoprotein complex", "d": ["The directed movement of a messenger ribonucleoprotein complex along microtubules in axons, towards the presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0001974", "l": "blood vessel remodeling", "d": ["The reorganization or renovation of existing blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0035316", "l": "non-sensory hair organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0033195", "l": "response to alkyl hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900380", "l": "negative regulation of asperthecin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of asperthecin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051517", "l": "negative regulation of bipolar cell growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0062098", "l": "regulation of programmed necrotic cell death", "d": ["Any process that modulates the frequency, rate or extent of programmed necrotic cell death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031552", "l": "negative regulation of brain-derived neurotrophic factor-activated receptor activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902829", "l": "regulation of spinal cord association neuron differentiation", "d": ["Any process that modulates the frequency, rate or extent of spinal cord association neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000356", "l": "regulation of kidney smooth muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of kidney smooth muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140544", "l": "septin collar organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising the septin collar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901730", "l": "monensin A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monensin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006452", "l": "translational frameshifting", "d": ["A mechanism whereby different proteins may result from a single mRNA molecule, due to a change in the parsing of three nucleotides per codon relative to an initiating AUG codon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905619", "l": "regulation of alpha-(1->3)-fucosyltransferase activity", "d": ["Any process that modulates the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072107", "l": "positive regulation of ureteric bud formation", "d": ["Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904973", "l": "positive regulation of viral translation", "d": ["Any process that activates or increases the frequency, rate or extent of viral translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905661", "l": "regulation of telomerase RNA reverse transcriptase activity", "d": ["Any process that modulates the frequency, rate or extent of telomerase RNA reverse transcriptase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106279", "l": "negative regulation of UDP-N-acetylglucosamine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0043102", "l": "amino acid salvage", "d": ["Any process which produces an amino acid from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0036035", "l": "osteoclast development", "d": ["The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002105", "l": "endonucleolytic cleaveage between LSU-rRNA and 4.5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)", "d": ["Endonucleolytic cleavage between the LSU-rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120195", "l": "positive regulation of anther dehiscence", "d": ["Any process that activates or increases the frequency, rate or extent of anther dehiscence."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021902", "l": "commitment of neuronal cell to specific neuron type in forebrain", "d": ["The commitment of neuronal precursor cells to become specialized types of neurons in the forebrain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010064", "l": "embryonic shoot morphogenesis", "d": ["The process in which the anatomical structures of embryonic shoot are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032761", "l": "positive regulation of lymphotoxin A production", "d": ["Any process that activates or increases the frequency, rate, or extent of lymphotoxin A production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090187", "l": "positive regulation of pancreatic juice secretion", "d": ["Any process that increases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900200", "l": "mesenchymal cell apoptotic process involved in metanephros development", "d": ["Any mesenchymal cell apoptotic process that is involved in metanephros development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002547", "l": "positive regulation of tissue kallikrein-kinin cascade", "d": ["Any process that activates or increases the frequency, rate, or extent of the tissue kallikrein-kinin cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905623", "l": "positive regulation of leaf development", "d": ["Any process that activates or increases the frequency, rate or extent of leaf development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120163", "l": "negative regulation of cold-induced thermogenesis", "d": ["Any process that stops, prevents, or reduces the rate of cold-induced thermogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000262", "l": "positive regulation of blood coagulation, common pathway", "d": ["Any process that activates or increases the frequency, rate or extent of blood coagulation, common pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901824", "l": "delta-carotene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of delta-carotene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.413456430472493", "identifiers": [{"i": "GO:0051282", "l": "regulation of sequestering of calcium ion", "d": ["Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905827", "l": "positive regulation of selenocysteine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of selenocysteine metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.124646994401843", "identifiers": [{"i": "GO:0008299", "l": "isoprenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072660", "l": "maintenance of protein location in plasma membrane", "d": ["Any process in which a protein is maintained in a specific location in the plasma membrane, and is prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039501", "l": "suppression by virus of host type I interferon production", "d": ["Any viral process that results in the inhibition of host cell type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033552", "l": "response to vitamin B3", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046045", "l": "TMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of TMP, ribosylthymine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061833", "l": "protein localization to tricellular tight junction", "d": ["A process in which a protein is transported to, or maintained in, a location within a tricellular tight junction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.712091546727706", "identifiers": [{"i": "GO:0071459", "l": "protein localization to chromosome, centromeric region", "d": ["Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0052542", "l": "defense response by callose deposition", "d": ["Any process in which callose is transported to, and/or maintained in, a specific location during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0060343", "l": "trabecula formation", "d": ["The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903025", "l": "regulation of RNA polymerase II regulatory region sequence-specific DNA binding", "d": ["Any process that modulates the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1903564", "l": "regulation of protein localization to cilium", "d": ["Any process that modulates the frequency, rate or extent of protein localization to cilium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.590000485671659", "identifiers": [{"i": "GO:0070887", "l": "cellular response to chemical stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901631", "l": "positive regulation of presynaptic membrane organization", "d": ["Any process that activates or increases the frequency, rate or extent of presynaptic membrane organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0039702", "l": "viral budding via host ESCRT complex", "d": ["Viral budding which uses a host ESCRT protein complex, or complexes, to mediate the budding process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019365", "l": "pyridine nucleotide salvage", "d": ["Any process that generates a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base, from derivatives of them without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015752", "l": "D-ribose transmembrane transport", "d": ["The process in which D-ribose is transported across a lipid bilayer, from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900308", "l": "positive regulation of maltoheptaose transport", "d": ["Any process that activates or increases the frequency, rate or extent of maltoheptaose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060903", "l": "positive regulation of meiosis I", "d": ["Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061086", "l": "negative regulation of histone H3-K27 methylation", "d": ["Any process that decreases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080056", "l": "petal vascular tissue pattern formation", "d": ["Vascular tissue pattern formation as it occurs in the petal of vascular plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071954", "l": "chemokine (C-C motif) ligand 11 production", "d": ["The appearance of chemokine (C-C motif) ligand 11 (CCL11, also known as eotaxin-1) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905514", "l": "positive regulation of short-term synaptic potentiation", "d": ["Any process that activates or increases the frequency, rate or extent of short-term synaptic potentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1904948", "l": "midbrain dopaminergic neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a midbrain dopaminergic neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905011", "l": "transmembrane phosphate ion transport from cytosol to vacuole", "d": ["The directed movement of phosphate ions from the cytosol across the vacuolar membrane and into the vacuolar lumen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904714", "l": "regulation of chaperone-mediated autophagy", "d": ["Any process that modulates the frequency, rate or extent of chaperone-mediated autophagy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905450", "l": "negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075274", "l": "negative regulation of zygosporangium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071247", "l": "cellular response to chromate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060390", "l": "regulation of SMAD protein signal transduction", "d": ["Any process that modulates the rate, frequency or extent of SMAD protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0021514", "l": "ventral spinal cord interneuron differentiation", "d": ["The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905061", "l": "negative regulation of cardioblast proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardioblast proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0042116", "l": "macrophage activation", "d": ["A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071297", "l": "cellular response to cobalamin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036399", "l": "TCR signalosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a TCR signalosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072670", "l": "mitochondrial tRNA threonylcarbamoyladenosine modification", "d": ["The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in mitochondrial tRNAs that decode ANN codons (where N is any base)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.062480095235458", "identifiers": [{"i": "GO:0032886", "l": "regulation of microtubule-based process", "d": ["Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0032197", "l": "retrotransposition", "d": ["A type of transposition in which a transposable element (transposon) copies and pastes itself into a different genomic location by transcription and convertsion of the transcribed RNA back into DNA through reverse transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901274", "l": "2-dehydro-3-deoxy-D-gluconic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 2-dehydro-3-deoxy-D-gluconic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0048752", "l": "semicircular canal morphogenesis", "d": ["The process in which the anatomical structures of the semicircular canals are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042759", "l": "long-chain fatty acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a long-chain fatty acid, a fatty acid with an aliphatic tail of 13 to 21 carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036085", "l": "GDP-fucose import into Golgi lumen", "d": ["The directed movement of GDP-fucose into the Golgi lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043638", "l": "puromycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of puromycin, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046053", "l": "dAMP metabolic process", "d": ["The chemical reactions and pathways involving dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060509", "l": "type I pneumocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036306", "l": "embryonic heart tube elongation", "d": ["The developmental growth that results in the increase in length of the embryonic heart tube. The embryonic heart tube is an epithelial tube that will give rise to the mature heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042047", "l": "W-molybdopterin cofactor biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051296", "l": "establishment of meiotic spindle orientation", "d": ["Any process that set the alignment of meiotic spindle relative to other cellular structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070499", "l": "exosporium assembly", "d": ["A process that is carried out at the cellular level which results in the formation of an exosporium, the outermost layer of a bacterial endospore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0019566", "l": "arabinose metabolic process", "d": ["The chemical reactions and pathways involving arabinose, arabino-pentose. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides etc. D-arabinose is a constituent of arabinonucleosides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097093", "l": "polyacyltrehalose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polyacyltrehalose, a pentaacylated, trehalose-based glycolipid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140548", "l": "envenomation resulting in blood agglutination in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with specific proteins binding to cell-surface carbohydrates and causing calcium-dependent agglutination of blood cells in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905125", "l": "positive regulation of glucosylceramidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of glucosylceramidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901354", "l": "response to L-canavanine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900160", "l": "plastid chromosome packaging", "d": ["A process in which plastidial DNA and associated proteins organize into a compact, orderly structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060279", "l": "positive regulation of ovulation", "d": ["Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098586", "l": "cellular response to virus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075055", "l": "positive regulation of penetration peg formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002442", "l": "serotonin secretion involved in inflammatory response", "d": ["The regulated release of serotonin by a cell as part of an inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014007", "l": "negative regulation of microglia differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000809", "l": "positive regulation of synaptic vesicle clustering", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle clustering."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0007480", "l": "imaginal disc-derived leg morphogenesis", "d": ["The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000548", "l": "negative regulation of dendritic cell dendrite assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990641", "l": "response to iron ion starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of iron ion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902811", "l": "positive regulation of skeletal muscle fiber differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990059", "l": "fruit valve development", "d": ["The process whose specific outcome is the progression of the fruit valve over time, from its formation to the mature structure. The fruit valve is a part of a fruit that splits apart when the fruit dehisces."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905148", "l": "negative regulation of smooth muscle hypertrophy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904258", "l": "nuclear dicing body assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a nuclear dicing body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902609", "l": "(R)-2-hydroxy-alpha-linolenic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (R)-2-hydroxy-alpha-linolenic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043090", "l": "amino acid import", "d": ["The directed movement of amino acids into a cell or organelle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905484", "l": "negative regulation of motor neuron migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034229", "l": "ethanolamine transport", "d": ["The directed movement of ethanolamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010917", "l": "negative regulation of mitochondrial membrane potential", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007475", "l": "apposition of dorsal and ventral imaginal disc-derived wing surfaces", "d": ["The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044556", "l": "envenomation resulting in negative regulation of heart rate in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of the heart rate of the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0048581", "l": "negative regulation of post-embryonic development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0019673", "l": "GDP-mannose metabolic process", "d": ["The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000319", "l": "regulation of T-helper 17 cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of T-helper 17 cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901499", "l": "response to hexane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexane stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.188826368221726", "identifiers": [{"i": "GO:0072329", "l": "monocarboxylic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0009157", "l": "deoxyribonucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061856", "l": "Golgi calcium ion transmembrane transport", "d": ["A process in which a calcium ion is transported from one side of a Golgi membrane to the other by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0031920", "l": "pyridoxal transport", "d": ["The directed movement of pyridoxal into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010664", "l": "negative regulation of striated muscle cell apoptotic process", "d": ["Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0043704", "l": "photoreceptor cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140845", "l": "regulation of promoter clearance from RNA polymerase II promoter", "d": ["A process that modulates the frequency, rate or extent of the transition from the initiation to the elongation phases of transcription by RNA polymerase II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010696", "l": "positive regulation of mitotic spindle pole body separation", "d": ["Any process that increases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072566", "l": "chemokine (C-X-C motif) ligand 1 production", "d": ["The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033388", "l": "putrescine biosynthetic process from arginine", "d": ["The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045801", "l": "positive regulation of chitin-based cuticle tanning", "d": ["Any process that activates or increases the frequency, rate or extent of chitin-based cuticular tanning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048816", "l": "ocellus morphogenesis", "d": ["The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901909", "l": "diadenosine hexaphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diadenosine hexaphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0010811", "l": "positive regulation of cell-substrate adhesion", "d": ["Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:0052027", "l": "modulation by symbiont of host signal transduction pathway", "d": ["Any process in which an organism modulates the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905102", "l": "positive regulation of apoptosome assembly", "d": ["Any process that activates or increases the frequency, rate or extent of apoptosome assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002321", "l": "natural killer cell progenitor differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a natural killer cell progenitor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071076", "l": "RNA 3' uridylation", "d": ["The enzymatic addition of a sequence of uridylyl residues at the 3' end of an RNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140745", "l": "siRNA transcription", "d": ["The transcription of a small interfering RNA from an RNA template."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072295", "l": "specification of metanephric distal tubule identity", "d": ["The process in which the distal tubule of the metanephric nephron acquires its identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1901269", "l": "lipooligosaccharide metabolic process", "d": ["The chemical reactions and pathways involving lipooligosaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905445", "l": "positive regulation of clathrin coat assembly", "d": ["Any process that activates or increases the frequency, rate or extent of clathrin coat assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010617", "l": "circadian regulation of calcium ion oscillation", "d": ["Any process that modulates the concentration of cytosolic free calcium ion [Ca2+]cyt with a regularity of approximately 24 hours."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010944", "l": "negative regulation of transcription by competitive promoter binding", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves direct competition for interaction with a promoter binding site."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019465", "l": "aspartate transamidation", "d": ["The exchange of the amino group of aspartate, the anion derived from aspartic acid, for another amino group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902289", "l": "negative regulation of defense response to oomycetes", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of defense response to oomycetes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "42.756447418125269", "identifiers": [{"i": "GO:0065008", "l": "regulation of biological quality", "d": ["Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0009595", "l": "detection of biotic stimulus", "d": ["The series of events in which a biotic stimulus, one caused or produced by a living organism, is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000418", "l": "positive regulation of eosinophil migration", "d": ["Any process that activates or increases the frequency, rate or extent of eosinophil migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900585", "l": "arugosin metabolic process", "d": ["The chemical reactions and pathways involving arugosin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010903", "l": "negative regulation of very-low-density lipoprotein particle remodeling", "d": ["Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1905462", "l": "regulation of DNA duplex unwinding", "d": ["Any process that modulates the frequency, rate or extent of DNA duplex unwinding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035023", "l": "regulation of Rho protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of Rho protein signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0000183", "l": "rDNA heterochromatin formation", "d": ["The formation of heterochromatin at ribosomal DNA, characterized by the modified histone H3K9me3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045906", "l": "negative regulation of vasoconstriction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of vasoconstriction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0120065", "l": "pyloric antrum smooth muscle contraction", "d": ["A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the widest part of the pylorus that is continuous with the body of the stomach."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014916", "l": "regulation of lung blood pressure", "d": ["The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002013", "l": "detection of carbon dioxide by vasomotor center", "d": ["The process by a carbon dioxide stimulus is received and converted to a molecular signal by the vasomotor center of the central nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901365", "l": "funalenone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of funalenone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140027", "l": "contractile vacuole localization", "d": ["The directed movement of the contractile vacuole to a specific location."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0009309", "l": "amine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060043", "l": "regulation of cardiac muscle cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902521", "l": "response to etoposide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an etoposide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048830", "l": "adventitious root development", "d": ["The process whose specific outcome is the progression of adventitious root over time, from its formation to the mature structure. Adventitious roots are post-embryonic roots that develop from the plant shoot."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900245", "l": "positive regulation of MDA-5 signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of MDA-5 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:0072350", "l": "tricarboxylic acid metabolic process", "d": ["The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing three carboxyl (COOH) groups or anions (COO-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1903963", "l": "arachidonate transport", "d": ["The directed movement of an arachidonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905598", "l": "negative regulation of low-density lipoprotein receptor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045151", "l": "acetoin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acetoin, 3-hydroxy-2-butanone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0051657", "l": "maintenance of organelle location", "d": ["Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1901607", "l": "alpha-amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an alpha-amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1905323", "l": "telomerase holoenzyme complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a telomerase holoenzyme complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032877", "l": "positive regulation of DNA endoreduplication", "d": ["Any process that activates or increases the frequency, rate or extent of DNA endoreduplication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001050", "l": "negative regulation of tendon cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072760", "l": "cellular response to GW 7647", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043645", "l": "cephalosporin metabolic process", "d": ["The chemical reactions and pathways involving a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0050934", "l": "late stripe melanocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a late stripe melanocyte (LSM). In zebrafish, LSMs develop during the second phase (3-4 weeks of development) of the larva-to-adult transition (2-4 weeks of development)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036164", "l": "cell-abiotic substrate adhesion", "d": ["The attachment of a cell to an underlying abiotic (non-living) substrate via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904046", "l": "negative regulation of vascular endothelial growth factor production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140247", "l": "protein catabolic process at presynapse", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015848", "l": "spermidine transport", "d": ["The directed movement of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to putrescine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000334", "l": "positive regulation of blood microparticle formation", "d": ["Any process that activates or increases the frequency, rate or extent of blood microparticle formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042201", "l": "N-cyclopropylmelamine metabolic process", "d": ["The chemical reactions and pathways involving N-cyclopropylmelamine, a triazine compound commonly used as an insect growth regulator insecticide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048711", "l": "positive regulation of astrocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of astrocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0034398", "l": "telomere tethering at nuclear periphery", "d": ["The process in which a telomere is maintained in a specific location at the nuclear periphery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003425", "l": "establishment of mitotic spindle orientation involved in growth plate cartilage chondrocyte division", "d": ["A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures and contributes to oriented chondrocyte division in the growth plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.664775500092716", "identifiers": [{"i": "GO:0070227", "l": "lymphocyte apoptotic process", "d": ["Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002841", "l": "negative regulation of T cell mediated immune response to tumor cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a T cell mediated immune response to tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072388", "l": "flavin adenine dinucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046797", "l": "viral procapsid maturation", "d": ["The refolding and structural rearrangements of individual capsid subunits to transition from the intermediate procapsid, to the more stable capsid structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003063", "l": "negative regulation of heart rate by acetylcholine", "d": ["The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors on the pacemaker cells and decreases the rate of heart muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036372", "l": "opsin transport", "d": ["The directed movement of an opsin (a G protein-coupled receptor of photoreceptor cells) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0045047", "l": "protein targeting to ER", "d": ["The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035962", "l": "response to interleukin-13", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051799", "l": "negative regulation of hair follicle development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061068", "l": "urethra development", "d": ["The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010726", "l": "positive regulation of hydrogen peroxide metabolic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060951", "l": "neural crest-derived cardiac glial cell differentiation", "d": ["The process in which a neural crest cell acquires the specialized features of a glial cell of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:2000833", "l": "positive regulation of steroid hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of steroid hormone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904308", "l": "cellular response to desipramine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0002835", "l": "negative regulation of response to tumor cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to tumor cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048868", "l": "pollen tube development", "d": ["The process whose specific outcome is the progression of a pollen tube over time, from its initial formation to a mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0061727", "l": "methylglyoxal catabolic process to lactate", "d": ["The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into lactate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0071669", "l": "plant-type cell wall organization or biogenesis", "d": ["A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1903801", "l": "L-leucine import across plasma membrane", "d": ["The directed movement of L-leucine from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021848", "l": "neuroblast division in subpallium", "d": ["The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072758", "l": "response to topoisomerase inhibitor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.706056554619465", "identifiers": [{"i": "GO:0006352", "l": "DNA-templated transcription initiation", "d": ["The initial step of transcription, consisting of the assembly of the RNA polymerase preinitiation complex (PIC) at a gene promoter, as well as the formation of the first few bonds of the RNA transcript. Transcription initiation includes abortive initiation events, which occur when the first few nucleotides are repeatedly synthesized and then released, and ends when promoter clearance takes place."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060152", "l": "microtubule-based peroxisome localization", "d": ["The microtubule-based process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901814", "l": "astaxanthin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of astaxanthin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905426", "l": "positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0052802", "l": "nitroimidazole metabolic process", "d": ["The chemical reactions and pathways involving nitroimidazoles, imidazole derivatives with a nitro group attached to one ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001188", "l": "regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell", "d": ["Any process that modulates the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904735", "l": "regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase", "d": ["Any process that modulates the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901468", "l": "positive regulation of ferulate catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of ferulate catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031450", "l": "negative regulation of slow-twitch skeletal muscle fiber contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of slow-twitch skeletal muscle contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.760111289607934", "identifiers": [{"i": "GO:0050867", "l": "positive regulation of cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032598", "l": "B cell receptor transport into immunological synapse", "d": ["The directed movement of a B cell receptor into an immunological synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902630", "l": "regulation of membrane hyperpolarization", "d": ["Any process that modulates the frequency, rate or extent of membrane hyperpolarization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "45.497029033175423", "identifiers": [{"i": "GO:0042592", "l": "homeostatic process", "d": ["Any biological process involved in the maintenance of an internal steady state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0006522", "l": "alanine metabolic process", "d": ["The chemical reactions and pathways involving alanine, 2-aminopropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905317", "l": "inferior endocardial cushion morphogenesis", "d": ["The developmental process by which an inferior endocardial cushion is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900304", "l": "negative regulation of laminaritriose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of laminaritriose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003176", "l": "aortic valve development", "d": ["The progression of the aortic valve over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014830", "l": "arteriole smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the arteriole. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The arteriole is the smallest division of the artery located between the muscular arteries and the capillaries."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000351", "l": "regulation of endothelial cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0000754", "l": "adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion", "d": ["In organisms that undergo conjugation with cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses. An example of this is the adaptation to pheromone during conjugation with cellular fusion in Saccharomyces cerevisiae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0097065", "l": "anterior head development", "d": ["The process whose specific outcome is the progression of the anterior part of the head over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003346", "l": "epicardium-derived cell migration to the myocardium", "d": ["The orderly movement of a cell that have undergone an epithelial to mesenchymal transition from the epicardium into the myocardium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061051", "l": "positive regulation of cell growth involved in cardiac muscle cell development", "d": ["Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072300", "l": "positive regulation of metanephric glomerulus development", "d": ["Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018028", "l": "peptidyl-lysine myristoylation", "d": ["The myristoylation of peptidyl-lysine to form peptidyl-N6-myristoyl-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021611", "l": "facial nerve formation", "d": ["The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902847", "l": "regulation of neuronal signal transduction", "d": ["Any process that modulates the frequency, rate or extent of neuronal signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035333", "l": "Notch receptor processing, ligand-dependent", "d": ["The proteolytic cleavages to the Notch protein that occur as a result of ligand binding. Ligand binding at the cell surface exposes an otherwise inaccessible cleavage site in the extracellular portion of Notch, which when cleaved releases a membrane-tethered form of the Notch intracellular domain. Subsequent cleavage within the transmembrane domain then leads to the release of the soluble Notch intracellular domain (NICD)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.975674484632918", "identifiers": [{"i": "GO:0051093", "l": "negative regulation of developmental process", "d": ["Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.083168145531296", "identifiers": [{"i": "GO:0009060", "l": "aerobic respiration", "d": ["The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046068", "l": "cGMP metabolic process", "d": ["The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034304", "l": "actinomycete-type spore formation", "d": ["The process in which differentiated, resting cells are formed from a substrate mycelium; characteristic of many members of the order Actinomycetales."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0016476", "l": "regulation of embryonic cell shape", "d": ["Any process that modulates the surface configuration of an embryonic cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021780", "l": "glial cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a glial cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061256", "l": "mesonephric podocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000742", "l": "regulation of anterior head development", "d": ["Any process that modulates the frequency, rate or extent of anterior head development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061725", "l": "cytosolic lipolysis", "d": ["The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045809", "l": "positive regulation of establishment of competence for transformation", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of competence for transformation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071587", "l": "CAAX-box protein modification", "d": ["The covalent alteration of one or more amino acid residues within the CAAX box region of CAAX box proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0019684", "l": "photosynthesis, light reaction", "d": ["The light reactions of photosynthesis, which take place in photosystems II and I. Light energy is harvested and used to power the transfer of electrons among a series of electron donors and acceptors. The final electron acceptor is NADP+, which is reduced to NADPH. NADPH generated from light reactions is used in sugar synthesis in dark reactions. Light reactions also generate a proton motive force across the thylakoid membrane, and the proton gradient is used to synthesize ATP. There are two chemical reactions involved in the light reactions: water oxidation in photosystem II, and NADP reduction in photosystem I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048841", "l": "regulation of axon extension involved in axon guidance", "d": ["Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000041", "l": "negative regulation of planar cell polarity pathway involved in axis elongation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in axis elongation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048473", "l": "D-methionine transport", "d": ["The directed movement of D-methionine into, out of, within, or between cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098747", "l": "slow, calcium ion-dependent exocytosis of neurotransmitter", "d": ["The slow, second phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on high affinity calcium sensors and decays slowly, typically with a decay constant of over 100ms. The underlying molecular mechanisms of this process are distinct from those of the earlier, fast phase of release."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044546", "l": "NLRP3 inflammasome complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the NLRP3 inflammasome complex, occurring at the level of an individual cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046619", "l": "lens placode formation involved in camera-type eye formation", "d": ["Establishment and formation of the optic placode, paired ectodermal placodes that become invaginated to form the embryonic lens vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900504", "l": "negative regulation of cellulosome assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellulosome assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043965", "l": "disruption of host adenylate cyclase-mediated signal transduction", "d": ["Any process in which an organism interferes with adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043201", "l": "response to leucine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.82875340147023", "identifiers": [{"i": "GO:0051241", "l": "negative regulation of multicellular organismal process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018063", "l": "cytochrome c-heme linkage", "d": ["The linkage of cytochromes and other heme proteins to heme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0048641", "l": "regulation of skeletal muscle tissue development", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle tissue development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070235", "l": "regulation of activation-induced cell death of T cells", "d": ["Any process that modulates the occurrence or rate of activation-induced cell death of T cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044083", "l": "modulation by symbiont of host Rho protein signal transduction", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of Rho protein signal transduction in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902466", "l": "positive regulation of histone H3-K27 trimethylation", "d": ["Any process that activates or increases the frequency, rate or extent of histone H3-K27 trimethylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0120078", "l": "cell adhesion involved in sprouting angiogenesis", "d": ["The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the formation of a blood vessel network."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046347", "l": "mannosamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903237", "l": "negative regulation of leukocyte tethering or rolling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte tethering or rolling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035694", "l": "mitochondrial protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0003182", "l": "coronary sinus valve morphogenesis", "d": ["The process in which the structure of the coronary sinus valve is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900551", "l": "N',N'',N'''-triacetylfusarinine C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of N',N'',N'''-triacetylfusarinine C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902639", "l": "propan-2-ol metabolic process", "d": ["The chemical reactions and pathways involving propan-2-ol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.465174152298118", "identifiers": [{"i": "GO:0060840", "l": "artery development", "d": ["The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0007340", "l": "acrosome reaction", "d": ["The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the zona pellucida."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046618", "l": "xenobiotic export from cell", "d": ["The directed movement of a xenobiotic from a cell, into the extracellular region. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0031269", "l": "pseudopodium assembly", "d": ["The assembly of a pseudopodium by rearrangement of the actin cytoskeleton and overlying membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990256", "l": "signal clustering", "d": ["Grouping of multiple copies of a signal at a cellular location. May promote receptor clustering and alter the signal transduction response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904143", "l": "positive regulation of carotenoid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of carotenoid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905855", "l": "positive regulation of heparan sulfate binding", "d": ["Any process that activates or increases the frequency, rate or extent of heparan sulfate binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150054", "l": "regulation of postsynaptic neurotransmitter receptor diffusion trapping", "d": ["Any process that modulates the frequency, rate or extent of postsynaptic neurotransmitter receptor diffusion trapping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0021999", "l": "neural plate anterior/posterior regionalization", "d": ["The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0071281", "l": "cellular response to iron ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090091", "l": "positive regulation of extracellular matrix disassembly", "d": ["Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045650", "l": "negative regulation of macrophage differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075031", "l": "positive regulation of formation of symbiont germ tube hook structure for appressorium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of symbiont germ tube hook structure formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1903844", "l": "regulation of cellular response to transforming growth factor beta stimulus", "d": ["Any process that modulates the frequency, rate or extent of cellular response to transforming growth factor beta stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042956", "l": "maltodextrin transmembrane transport", "d": ["The directed movement of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:1901985", "l": "positive regulation of protein acetylation", "d": ["Any process that activates or increases the frequency, rate or extent of protein acetylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032670", "l": "regulation of interleukin-26 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-26 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021732", "l": "midbrain-hindbrain boundary maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904078", "l": "positive regulation of estrogen biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of estrogen biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042966", "l": "biotin carboxyl carrier protein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the biotin carboxyl carrier protein, a subunit of acetyl-coenzyme A carboxylase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1905269", "l": "positive regulation of chromatin organization", "d": ["Any process that activates or increases the frequency, rate or extent of chromatin organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034474", "l": "U2 snRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a U2 snRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033053", "l": "D-glutamine metabolic process", "d": ["The chemical reactions and pathways involving D-glutamine, the D-enantiomer of the amino acid glutamine, i.e. (2R)-2,5-diamino-5-oxopentanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.261443428098588", "identifiers": [{"i": "GO:0051588", "l": "regulation of neurotransmitter transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106023", "l": "regulation of pupariation", "d": ["Any process that modulates the onset of pupariation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042313", "l": "protein kinase C deactivation", "d": ["Any process resulting in the inhibition or termination of the activity of protein kinase C."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031990", "l": "mRNA export from nucleus in response to heat stress", "d": ["The directed movement of mRNA from the nucleus to the cytoplasm during a heat stimulus, a temperature stimulus above the optimal temperature for the organism; in particular, a process that enables an organism withstand exposure to temperatures that would otherwise lethally impair poly(A)+ mRNA-nucleus export."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035158", "l": "regulation of tube diameter, open tracheal system", "d": ["Ensuring that a tube in an open tracheal system is of the correct diameter. When primary branches form their lumens are small (less than 2 micrometers) in caliber and must undergo regulated expansion during larval life to reach their mature size."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072184", "l": "renal vesicle progenitor cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the renal vesicle progenitor cells of the kidney as it progresses from its formation to the mature state. A renal vesicle progenitor cell is a cell that will give rise to terminally differentiated cells of the renal vesicle without self-renewing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.42903515889401", "identifiers": [{"i": "GO:0006164", "l": "purine nucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036417", "l": "tRNA destabilization", "d": ["Any process that decreases the stability of a tRNA molecule, making it more vulnerable to degradative processes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046280", "l": "chalcone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of chalcone, phenyl steryl ketone or its hydroxylated derivatives."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045479", "l": "vesicle targeting to fusome", "d": ["The recruitment of vesicles to the fusome. The vesicles become the fusome tubule network and are necessary for the assembly of the fusome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090008", "l": "hypoblast development", "d": ["The process whose specific outcome is the progression of the hypoblast over time, from its formation to the mature structure. The hypoblast is a tissue formed from the inner cell mass that lies beneath the epiblast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.314728742240533", "identifiers": [{"i": "GO:0010721", "l": "negative regulation of cell development", "d": ["Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990416", "l": "cellular response to brain-derived neurotrophic factor stimulus", "d": ["A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brain-derived neurotrophic factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007494", "l": "midgut development", "d": ["The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905447", "l": "negative regulation of mitochondrial ATP synthesis coupled electron transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045729", "l": "respiratory burst at fertilization", "d": ["The phase of elevated metabolic activity, during which oxygen consumption increases, that occurs at fertilization. An enhanced uptake of oxygen leads to the production of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Capacitation, a necessary prerequisite event to successful fertilization, can be induced by reactive oxygen species in vitro; hydrogen peroxide is used as an extracellular oxidant to cross-link the protective surface envelopes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0120054", "l": "intestinal motility", "d": ["Contractions of the intestinal tract that include peristalsis (moving contents onward) and non-peristaltic movement (moving contents back and forth)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071607", "l": "macrophage inflammatory protein-1 gamma production", "d": ["The appearance of macrophage inflammatory protein-1 gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000880", "l": "positive regulation of dipeptide transport", "d": ["Any process that activates or increases the frequency, rate or extent of dipeptide transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.881813014728969", "identifiers": [{"i": "GO:0010256", "l": "endomembrane system organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035263", "l": "genital disc sexually dimorphic development", "d": ["The sex-specific patterns of primoridia growth and differentiation in the genital imaginal disc. The anal primordium of the genital disc develops in both sexes, but depending on the genetic sex gives rise to either male or female analia. Depending on the genetic sex, only one of the two genital primordia develop. In females the female genital primordium develops and gives rise to the female genitalia whereas the male primordium is repressed. Conversely, in males the male genital primordium develops and gives rise to the male genitalia whereas the female genital primordium is repressed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033343", "l": "positive regulation of collagen binding", "d": ["Any process that activates or increases the frequency, rate or extent of collagen binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0160021", "l": "maternal-to-zygotic transition of gene expression", "d": ["Any process that modulates the frequency, rate or extent of gene expression by which developmental control passes from the maternal genome to the zygotic genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042811", "l": "pheromone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0009174", "l": "pyrimidine ribonucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905741", "l": "calcium export from the mitochondrion involved in positive regulation of presynaptic cytosolic calcium concentration", "d": ["Any mitochondrial calcium release that is involved in positive regulation of presynaptic cytosolic calcium concentration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030382", "l": "sperm mitochondrion organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of sperm mitochondria; the process in which they take on their characteristic morphology; they are flattened, elongated, and arranged circumferentially into a tight helical coil around the tail-dense fibers of the mature sperm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904440", "l": "positive regulation of iron ion import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of iron ions import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0060082", "l": "eye blink reflex", "d": ["The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034296", "l": "zygospore formation", "d": ["The process in which zygospores are formed. Zygospores are characteristic of the zygomycete fungi (phylum Zygomycota) thick-walled and darkly colored, and usually heavily ornamented as well, with many spines or ridges. It is formed between two specialized organs called suspensors, which are themselves usually heavily ornamented, one from each mating partner. The zygospore forms between them and then breaks away."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035564", "l": "regulation of kidney size", "d": ["Any process that modulates the size of a kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032645", "l": "regulation of granulocyte macrophage colony-stimulating factor production", "d": ["Any process that modulates the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043354", "l": "enucleate erythrocyte maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001294", "l": "malonyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of malonyl-CoA, the S-malonyl derivative of coenzyme A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902753", "l": "negative regulation of renal amino acid absorption", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of renal amino acid absorption."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000366", "l": "intergenic mRNA trans splicing", "d": ["The joining together of two independently transcribed RNAs from two different genes, each of which also produces mRNA(s) via cis-splicing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.885519852735264", "identifiers": [{"i": "GO:0006631", "l": "fatty acid metabolic process", "d": ["The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003106", "l": "negative regulation of glomerular filtration by angiotensin", "d": ["The process in which angiotensin directly decreases the rate of glomerular filtration in the kidney. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900348", "l": "regulation of methane biosynthetic process from methylamine", "d": ["Any process that modulates the frequency, rate or extent of methane biosynthetic process from methylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007384", "l": "specification of segmental identity, thorax", "d": ["The specification of the characteristic structures of the thoracic segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021503", "l": "neural fold bending", "d": ["The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051001", "l": "negative regulation of nitric-oxide synthase activity", "d": ["Any process that stops or reduces the activity of the enzyme nitric-oxide synthase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902985", "l": "mitotic pre-replicative complex assembly", "d": ["Any pre-replicative complex assembly involved in mitotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904860", "l": "DNA synthesis involved in mitotic DNA replication", "d": ["Any DNA biosynthetic process that is involved in mitotic DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0034307", "l": "regulation of ascospore formation", "d": ["Any process that modulates the frequency, rate or extent of ascospore formation. An example of this process is found in Saccharomyces cerevisiae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034125", "l": "negative regulation of MyD88-dependent toll-like receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900115", "l": "extracellular regulation of signal transduction", "d": ["Any regulation of signal transduction that takes place in the extracellular region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0098515", "l": "detection of low humidity stimulus involved in sensory perception", "d": ["The series of events in which a low humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of low humidity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033382", "l": "maintenance of granzyme B location in T cell secretory granule", "d": ["A process in which the protease granyme B is maintained in a secretory granule in a T cell and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0001905", "l": "activation of membrane attack complex", "d": ["The activation of the membrane attack complex components of the complement cascade which can result in death of a target cell through cytolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904229", "l": "regulation of succinate dehydrogenase activity", "d": ["Any process that modulates the frequency, rate or extent of succinate dehydrogenase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905883", "l": "regulation of triglyceride transport", "d": ["Any process that modulates the frequency, rate or extent of triglyceride transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032674", "l": "regulation of interleukin-5 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-5 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0015742", "l": "alpha-ketoglutarate transport", "d": ["The directed movement of alpha-ketoglutarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.056443926126086", "identifiers": [{"i": "GO:0007423", "l": "sensory organ development", "d": ["The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900496", "l": "positive regulation of butyryl-CoA biosynthetic process from acetyl-CoA", "d": ["Any process that activates or increases the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900444", "l": "negative regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030241", "l": "skeletal muscle myosin thick filament assembly", "d": ["The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in skeletal muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000053", "l": "argininosuccinate metabolic process", "d": ["The chemical reactions and pathways involving argininosuccinate, 2-(N(omega)-arginino)succinate, an intermediate in the ornithine-urea cycle, where it is synthesized from citrulline and aspartate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046814", "l": "coreceptor-mediated virion attachment to host cell", "d": ["The process by which a virion attaches to a host cell by binding to a co-receptor on the host cell surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006108", "l": "malate metabolic process", "d": ["The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030716", "l": "oocyte fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001031", "l": "positive regulation of cellular glucuronidation", "d": ["Any process that activates or increases the frequency, rate or extent of cellular glucuronidation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.003741351937961", "identifiers": [{"i": "GO:0009250", "l": "glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0000960", "l": "regulation of mitochondrial RNA catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009228", "l": "thiamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046937", "l": "phytochelatin metabolic process", "d": ["The chemical reactions and pathways involving phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.062480095235458", "identifiers": [{"i": "GO:0018904", "l": "ether metabolic process", "d": ["The chemical reactions and pathways involving organic ethers, any anhydride of the general formula R1-O-R2, formed between two identical or nonidentical organic hydroxy compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010578", "l": "regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of adenylate cyclase (AC) activity that is an integral part of a G protein-coupled receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072242", "l": "metanephric DCT cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric distal convoluted tubule cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0032608", "l": "interferon-beta production", "d": ["The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0006690", "l": "icosanoid metabolic process", "d": ["The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000025", "l": "regulation of leaf formation", "d": ["Any process that modulates the frequency, rate or extent of leaf formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.379321704503681", "identifiers": [{"i": "GO:0015804", "l": "neutral amino acid transport", "d": ["The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0106259", "l": "cell-to-cell migration in host", "d": ["The directional movement of a symbiont from one host cell to another."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0071921", "l": "cohesin loading", "d": ["The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1905483", "l": "regulation of motor neuron migration", "d": ["Any process that modulates the frequency, rate or extent of motor neuron migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.226136141113301", "identifiers": [{"i": "GO:0060986", "l": "endocrine hormone secretion", "d": ["The regulated release of a hormone into the circulatory system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000949", "l": "negative regulation of xyloglucan metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035261", "l": "external genitalia morphogenesis", "d": ["The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.133516115290618", "identifiers": [{"i": "GO:0032941", "l": "secretion by tissue", "d": ["The controlled release of a substance by a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905905", "l": "pharyngeal gland morphogenesis", "d": ["The developmental process by which a pharyngeal gland is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106385", "l": "dIMP salvage", "d": ["Any process which produces a dIMP from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0006115", "l": "ethanol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0052573", "l": "UDP-D-galactose metabolic process", "d": ["The chemical reactions and pathways involving UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902073", "l": "positive regulation of hypoxia-inducible factor-1alpha signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0035194", "l": "regulatory ncRNA-mediated post-transcriptional gene silencing", "d": ["A posttranscriptional gene silencing pathway in which regulatory RNAs elicit silencing of specific target genes, either by mRNA destabilization or inhibition of translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034301", "l": "endospore formation", "d": ["The process in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905592", "l": "negative regulation of optical nerve axon regeneration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of optical nerve axon regeneration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007171", "l": "activation of transmembrane receptor protein tyrosine kinase activity", "d": ["Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0045764", "l": "positive regulation of amino acid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009194", "l": "pyrimidine ribonucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900614", "l": "F-9775B biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of F-9775B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070340", "l": "detection of bacterial lipopeptide", "d": ["The series of events in which a bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019572", "l": "L-arabinose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-arabinose, the L-enantiomer of arabino-pentose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019361", "l": "2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031070", "l": "intronic snoRNA processing", "d": ["The biogenesis of a snoRNA molecule which resides within, and is processed from, the intron of a pre-mRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0006177", "l": "GMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043642", "l": "novobiocin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045976", "l": "negative regulation of mitotic cell cycle, embryonic", "d": ["Any process that stops, prevents or reduces the rate or extent of progression through the embryonic mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001059", "l": "D-tagatose 6-phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a D-tagatose 6-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060782", "l": "regulation of mesenchymal cell proliferation involved in prostate gland development", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the prostate gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045960", "l": "positive regulation of complement activation, classical pathway", "d": ["Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0043984", "l": "histone H4-K16 acetylation", "d": ["The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 16 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036339", "l": "lymphocyte adhesion to endothelial cell of high endothelial venule", "d": ["The attachment of a lymphocyte to an endothelial cell of a high endothelial venule (HEV) via adhesion molecules. A HEV cell is an endothelial cell that is cuboidal, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051977", "l": "lysophospholipid transport", "d": ["The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042218", "l": "1-aminocyclopropane-1-carboxylate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0031297", "l": "replication fork processing", "d": ["The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015988", "l": "energy coupled proton transmembrane transport, against electrochemical gradient", "d": ["The transport of protons across a membrane and against an electrochemical gradient, using energy from a source such as ATP hydrolysis, light, or electron transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071066", "l": "detection of mechanical stimulus involved in sensory perception of wind", "d": ["The series of events involved in the perception of wind in which a mechanical stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019263", "l": "adamantanone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0034110", "l": "regulation of homotypic cell-cell adhesion", "d": ["Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034427", "l": "nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'", "d": ["The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0040031", "l": "snRNA modification", "d": ["The covalent alteration of one or more nucleotides within snRNA, resulting in a change in the properties of the snRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048216", "l": "negative regulation of Golgi vesicle fusion to target membrane", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Golgi vesicle fusion to target membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071268", "l": "homocysteine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of homocysteine, 2-amino-4-sulfanylbutanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0039532", "l": "negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the series of a cytoplasmic pattern recognition receptor signaling pathway in response to a virus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072675", "l": "osteoclast fusion", "d": ["The plasma membrane fusion process that results in fusion of mononuclear osteoclasts to form a multinuclear osteoclast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900488", "l": "negative regulation of [2Fe-2S] cluster assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of [2Fe-2S] cluster assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051791", "l": "medium-chain fatty acid metabolic process", "d": ["The chemical reactions and pathways involving a medium-chain fatty acid, a fatty acid with an aliphatic tail of 6 to 12 carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044829", "l": "positive regulation by host of viral genome replication", "d": ["A process in which a host organism activates or increases the frequency, rate or extent of viral genome replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:1902412", "l": "regulation of mitotic cytokinesis", "d": ["Any process that modulates the frequency, rate or extent of mitotic cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0090452", "l": "lithium ion transmembrane transport", "d": ["The directed movement of lithium ions across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.576939455547432", "identifiers": [{"i": "GO:0044771", "l": "meiotic cell cycle phase transition", "d": ["The cell cycle process by which a cell commits to entering the next meiotic cell cycle phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0052778", "l": "diacetylchitobiose metabolic process", "d": ["The chemical reactions and pathways involving diacetylchitobiose, the N,N'-diacetylated derivative of chitobiose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044780", "l": "bacterial-type flagellum assembly", "d": ["The assembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046060", "l": "dATP metabolic process", "d": ["The chemical reactions and pathways involving dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002710", "l": "negative regulation of T cell mediated immunity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990834", "l": "response to odorant", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an odorant stimulus. An odorant is any substance capable of stimulating the sense of smell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000864", "l": "regulation of estradiol secretion", "d": ["Any process that modulates the frequency, rate or extent of estradiol secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904294", "l": "positive regulation of ERAD pathway", "d": ["Any process that activates or increases the frequency, rate or extent of ERAD pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0044365", "l": "envenomation resulting in modulation of platelet aggregation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change to the frequency, rate or extent of platelet aggregation in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002494", "l": "lipid antigen transport", "d": ["The directed movement of a lipid antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901004", "l": "ubiquinone-6 metabolic process", "d": ["The chemical reactions and pathways involving ubiquinone-6. Ubiquinone-6 is a ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0110107", "l": "regulation of imaginal disc-derived wing vein specification", "d": ["Any process that modulates the frequency, rate or extent of imaginal disc-derived wing vein specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0098513", "l": "detection of humidity", "d": ["The series of events in which a humidity stimulus is received and converted into a molecular signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035801", "l": "adrenal cortex development", "d": ["The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035096", "l": "larval midgut cell programmed cell death", "d": ["The stage-specific programmed cell death of cells of the larval midgut, during histolysis of the larval organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075189", "l": "positive regulation of hyphopodium formation", "d": ["Any process that activates or increases the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000180", "l": "negative regulation of androgen biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of androgen biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003042", "l": "vasoconstriction of artery involved in carotid body chemoreceptor response to lowering of systemic arterial blood pressure", "d": ["A process that is triggered by carotid body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032087", "l": "regulation of type IV site-specific deoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of a type IV restriction endodeoxyribonuclease activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0000001", "l": "mitochondrion inheritance", "d": ["The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034264", "l": "isopentenyl adenine metabolic process", "d": ["The chemical reactions and pathways involving the cytokinin 6-isopentenyladenine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.876036511014462", "identifiers": [{"i": "GO:0001894", "l": "tissue homeostasis", "d": ["A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045959", "l": "negative regulation of complement activation, classical pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900260", "l": "negative regulation of RNA-dependent RNA polymerase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0061805", "l": "mitotic spindle elongation (spindle phase three)", "d": ["The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900569", "l": "chanoclavine-I aldehyde biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chanoclavine-I aldehyde. Chanoclavine-I aldehyde is at a branching point in the biosynthetic pathways of fumigaclavine C and ergotamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051229", "l": "meiotic spindle disassembly", "d": ["The controlled breakdown of the spindle during a meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "37.16120279895393", "identifiers": [{"i": "GO:0043009", "l": "chordate embryonic development", "d": ["The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000603", "l": "regulation of secondary growth", "d": ["Any process that modulates the frequency, rate or extent of secondary growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036104", "l": "Kdo2-lipid A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of Kdo2-lipid A, a lipopolysaccharide (LPS) component."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901061", "l": "guaiacyl lignin metabolic process", "d": ["The chemical reactions and pathways involving guaiacyl lignin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0140271", "l": "hexose import across plasma membrane", "d": ["The directed movement of hexose from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060137", "l": "maternal process involved in parturition", "d": ["A reproductive process occurring in the mother that results in birth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045967", "l": "negative regulation of growth rate", "d": ["Any process that reduces the rate of growth of all or part of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903607", "l": "cytochrome c biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cytochrome c."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032829", "l": "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071394", "l": "cellular response to testosterone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048315", "l": "conidium formation", "d": ["The process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900176", "l": "negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0120040", "l": "regulation of macrophage proliferation", "d": ["Any process that modulates the frequency, rate or extent of macrophage proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0062224", "l": "positive regulation of somatic muscle development", "d": ["Any process that increases the rate, frequency or extent of somatic muscle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0048873", "l": "homeostasis of number of cells within a tissue", "d": ["Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040010", "l": "positive regulation of growth rate", "d": ["Any process that increases the rate of growth of all or part of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034033", "l": "purine nucleoside bisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0090277", "l": "positive regulation of peptide hormone secretion", "d": ["Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0020027", "l": "hemoglobin metabolic process", "d": ["The chemical reactions and pathways involving hemoglobin, including its uptake and utilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018068", "l": "peptidyl-L-2',4',5'-topaquinone biosynthetic process from peptidyl-tyrosine", "d": ["The modification of protein tyrosine to L-2',4',5'-topaquinone, characteristic of the active site of copper amine oxidases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905533", "l": "negative regulation of leucine import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leucine import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072084", "l": "specification of distal tubule identity", "d": ["The process in which the distal tubule of the kidney nephron acquires its identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046158", "l": "ocellus pigment metabolic process", "d": ["The chemical reactions and pathways involving ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120166", "l": "protoperithecium formation", "d": ["The process of producing fruiting body precursors, called protoperithecia. Protoperitheicium is a spherical structure that is formed in the sexual phase of ascomycetous fungi such as Neurospora crassa and Sordaria macrospora. Protoperithecium is formed by the enveloping of ascogonia cells by sterile hyphae and it develops into perithecium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903543", "l": "positive regulation of exosomal secretion", "d": ["Any process that activates or increases the frequency, rate or extent of exosomal secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905072", "l": "cardiac jelly development", "d": ["The process whose specific outcome is the progression of cardiac jelly over time, from its formation to the mature structure. The cardiac jelly is an acellular gelatinous matrix secreted by the myocardium and plays a central role in the septation of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019289", "l": "rhizobactin 1021 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046314", "l": "phosphocreatine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.349248930891576", "identifiers": [{"i": "GO:0031589", "l": "cell-substrate adhesion", "d": ["The attachment of a cell to the underlying substrate via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036333", "l": "hepatocyte homeostasis", "d": ["Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072059", "l": "cortical collecting duct development", "d": ["The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "62.34809373133632", "identifiers": [{"i": "GO:0044092", "l": "negative regulation of molecular function", "d": ["Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071306", "l": "cellular response to vitamin E", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002213", "l": "defense response to insect", "d": ["A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042621", "l": "poly(3-hydroxyalkanoate) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905075", "l": "positive regulation of tight junction disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of tight junction disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031065", "l": "positive regulation of histone deacetylation", "d": ["Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.938386572175233", "identifiers": [{"i": "GO:0098630", "l": "aggregation of unicellular organisms", "d": ["The clustering together of unicellular organisms in suspension form aggregates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990181", "l": "acetyl-CoA biosynthetic process from pantothenate", "d": ["The chemical reactions and pathways resulting in the formation of acetyl-CoA from pantothenate via phosphopantothenate and CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0019889", "l": "pteridine metabolic process", "d": ["The chemical reactions and pathways involving pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045903", "l": "positive regulation of translational fidelity", "d": ["Any process that increases the ability of the translational apparatus to interpret the genetic code."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0002445", "l": "type II hypersensitivity", "d": ["An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140891", "l": "tRNA-derived regulatory ncRNA processing", "d": ["A process leading to the generation of a functional small regulatory non-coding RNA derived from a tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.722653756574275", "identifiers": [{"i": "GO:0002685", "l": "regulation of leukocyte migration", "d": ["Any process that modulates the frequency, rate, or extent of leukocyte migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140539", "l": "regulation of melanotic encapsulation of foreign target", "d": ["Any process that modulates the frequency, rate or extent of melanotic encapsulation of foreign target."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0060444", "l": "branching involved in mammary gland duct morphogenesis", "d": ["The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007284", "l": "spermatogonial cell division", "d": ["The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051584", "l": "regulation of dopamine uptake involved in synaptic transmission", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of the catecholamine neurotransmitter dopamine into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097715", "l": "cellular response to viscosity", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0006573", "l": "valine metabolic process", "d": ["The chemical reactions and pathways involving valine, 2-amino-3-methylbutanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019857", "l": "5-methylcytosine metabolic process", "d": ["The chemical reactions and pathways involving 5-methylcytosine, a methylated base of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018095", "l": "protein polyglutamylation", "d": ["The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0003211", "l": "cardiac ventricle formation", "d": ["The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0006266", "l": "DNA ligation", "d": ["The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051946", "l": "regulation of glutamate uptake involved in transmission of nerve impulse", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0047497", "l": "mitochondrion transport along microtubule", "d": ["The directed movement of a mitochondrion along a microtubule, mediated by motor proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045984", "l": "negative regulation of pyrimidine nucleobase metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0006007", "l": "glucose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0035455", "l": "response to interferon-alpha", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0035835", "l": "indole alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006254", "l": "CTP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of CTP, cytidine 5'-triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905049", "l": "negative regulation of metallopeptidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of metallopeptidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0097355", "l": "protein localization to heterochromatin", "d": ["Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036247", "l": "phytochelatin 3 import into vacuole", "d": ["The directed movement of phytochelatin 3 (PC3) into the vacuole. Phytochelatin 3 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=3, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090393", "l": "sepal giant cell development", "d": ["The process aimed at the progression of a sepal giant cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0039516", "l": "modulation by virus of host catalytic activity", "d": ["The process in which a virus effects a change in host enzyme activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1904377", "l": "positive regulation of protein localization to cell periphery", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0046669", "l": "regulation of compound eye retinal cell programmed cell death", "d": ["Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097743", "l": "de novo centriole assembly via blepharoplast", "d": ["A de novo centriole assembly process observed in multi-ciliated sperm cells of some primitive land plants, and where centrioles are formed from a blepharoplast, ultimately giving rise to multiple cilia on the sperm surface."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015958", "l": "bis(5'-nucleosidyl) oligophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009255", "l": "Entner-Doudoroff pathway through 6-phosphogluconate", "d": ["A pathway that converts a carbohydrate to pyruvate and glyceraldehyde-3 phosphate by producing 6-phosphogluconate and then dehydrating it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010849", "l": "regulation of proton-transporting ATPase activity, rotational mechanism", "d": ["Any process that modulates the rate of ATP hydrolysis by an ATPase. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042860", "l": "achromobactin metabolic process", "d": ["The chemical reactions and pathways involving achromobactin, a citrate siderophore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035705", "l": "T-helper 17 cell chemotaxis", "d": ["The directed movement of a T-helper 17 cell in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0097120", "l": "receptor localization to synapse", "d": ["Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001870", "l": "positive regulation of complement activation, lectin pathway", "d": ["Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046402", "l": "O antigen metabolic process", "d": ["The chemical reactions and pathways involving the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061352", "l": "cell chemotaxis involved in Malpighian tubule morphogenesis", "d": ["The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.843307841253292", "identifiers": [{"i": "GO:0070647", "l": "protein modification by small protein conjugation or removal", "d": ["A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000047", "l": "regulation of cell-cell adhesion mediated by cadherin", "d": ["Any process that modulates the frequency, rate or extent of cell-cell adhesion mediated by cadherin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032760", "l": "positive regulation of tumor necrosis factor production", "d": ["Any process that activates or increases the frequency, rate or extent of tumor necrosis factor production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904962", "l": "plastid to vacuole vesicle-mediated transport", "d": ["The vesicle-mediated and directed movement of substances from plastid to vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032079", "l": "positive regulation of endodeoxyribonuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0014017", "l": "neuroblast fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0072237", "l": "metanephric proximal tubule development", "d": ["The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045660", "l": "positive regulation of neutrophil differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of neutrophil differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902173", "l": "negative regulation of keratinocyte apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0072234", "l": "metanephric nephron tubule development", "d": ["The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090321", "l": "positive regulation of chylomicron remnant clearance", "d": ["Any process that increases the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0002072", "l": "optic cup morphogenesis involved in camera-type eye development", "d": ["The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904772", "l": "response to tetrachloromethane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrachloromethane stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018339", "l": "peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid", "d": ["The modification of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid, typical of bacterial ribosomal protein S12."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.967140482697559", "identifiers": [{"i": "GO:0046660", "l": "female sex differentiation", "d": ["The establishment of the sex of a female organism by physical differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000477", "l": "regulation of metanephric podocyte development", "d": ["Any process that modulates the frequency, rate or extent of metanephric glomerular visceral epithelial cell development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044563", "l": "envenomation resulting in slowing of activation kinetics of voltage-gated potassium channel in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant slowing of the activation kinetics of the activity of a voltage-gated potassium channel in the bitten/stung organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0033564", "l": "anterior/posterior axon guidance", "d": ["The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0050770", "l": "regulation of axonogenesis", "d": ["Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0035909", "l": "aorta morphogenesis", "d": ["The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002332", "l": "transitional stage B cell differentiation", "d": ["The process in which immature B cells from the bone marrow become mature B cells in the spleen. Transitional stage B cells are subdivided into transitional one (T1) and transitional two (T2) stages and are short-lived and functionally incompetent."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0019878", "l": "lysine biosynthetic process via aminoadipic acid", "d": ["The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1904386", "l": "response to L-phenylalanine derivative", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001805", "l": "positive regulation of type III hypersensitivity", "d": ["Any process that activates or increases the frequency, rate or extent of type III hypersensitivity, a type of inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.54864505102816", "identifiers": [{"i": "GO:0006082", "l": "organic acid metabolic process", "d": ["The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0019363", "l": "pyridine nucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000246", "l": "positive regulation of FtsZ-dependent cytokinesis", "d": ["Any process that activates or increases the frequency, rate or extent of Ftsz-dependent cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018441", "l": "iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide", "d": ["The incorporation of iron into a 8Fe-7S iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide, found in nitrogenase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019420", "l": "dissimilatory sulfate reduction", "d": ["The reduction of sulfate to hydrogen sulfide, which acts as a terminal electron acceptor. Sulfate is activated to adenosine-phosphosulfate (APS) which is then reduced to sulfite, which is in turn reduced to hydrogen sulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050894", "l": "determination of affect", "d": ["Any process in which an emotional response is associated with a particular sensory stimulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043362", "l": "nucleate erythrocyte maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900588", "l": "violaceol I metabolic process", "d": ["The chemical reactions and pathways involving violaceol I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071358", "l": "cellular response to type III interferon", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.247878506479573", "identifiers": [{"i": "GO:0044282", "l": "small molecule catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000999", "l": "positive regulation of cellulose catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellulose catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002490", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000569", "l": "regulation of T-helper 2 cell activation", "d": ["Any process that modulates the frequency, rate or extent of T-helper 2 cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900011", "l": "negative regulation of corticotropin-releasing hormone receptor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of corticotropin-releasing hormone receptor activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032707", "l": "negative regulation of interleukin-23 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-23 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0052648", "l": "ribitol phosphate metabolic process", "d": ["The chemical reactions and pathways involving ribitol phosphates, any phosphorylated form of ribitol, the pentitol derived formally by reduction of the -CHO group of either D- or L-ribose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098532", "l": "histone H3-K27 trimethylation", "d": ["The modification of histone H3 by addition of three methyl groups to lysine at position 27 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061234", "l": "mesonephric glomerulus morphogenesis", "d": ["The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052576", "l": "carbohydrate storage", "d": ["The accumulation and maintenance in cells or tissues of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001193", "l": "maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II", "d": ["Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from an RNA polymerase II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043585", "l": "nose morphogenesis", "d": ["The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1902370", "l": "regulation of tRNA catabolic process", "d": ["Any process that modulates the frequency, rate or extent of tRNA catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090638", "l": "phosphatidylcholine biosynthesis from phosphatidylethanolamine", "d": ["The phosphatidylcholine biosynthetic process that depends on direct conversion of the phosphatidyl-base phosphatidylethanolamine to phosphatidylcholine by successive methylations."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022006", "l": "zona limitans intrathalamica formation", "d": ["The formation of the narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.261443428098588", "identifiers": [{"i": "GO:0030048", "l": "actin filament-based movement", "d": ["Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0042136", "l": "neurotransmitter biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003127", "l": "detection of nodal flow", "d": ["The series of events by which an endogenous stimulus is received by a cilium on a cell and converted to a molecular signal contributing to left/right asymmetry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0001676", "l": "long-chain fatty acid metabolic process", "d": ["The chemical reactions and pathways involving a long-chain fatty acid, a fatty acid with an aliphatic tail of 13 to 21 carbons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.576969997299727", "identifiers": [{"i": "GO:0006913", "l": "nucleocytoplasmic transport", "d": ["The directed movement of molecules between the nucleus and the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015960", "l": "diadenosine polyphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902918", "l": "poly(5-hydroxyvalerate) metabolic process", "d": ["The chemical reactions and pathways involving poly(5-hydroxyvalerate)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0030252", "l": "growth hormone secretion", "d": ["The regulated release of growth hormone from secretory granules into the blood."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019457", "l": "methionine catabolic process to succinyl-CoA", "d": ["The chemical reactions and pathways resulting in the breakdown of methionine into other compounds, including succinyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061530", "l": "aspartate secretion, neurotransmission", "d": ["The regulated release of aspartate by a cell in which the aspartate acts as a neurotransmitter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901186", "l": "positive regulation of ERBB signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of ERBB signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0009651", "l": "response to salt stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009767", "l": "photosynthetic electron transport chain", "d": ["A process, occurring as part of photosynthesis, in which light provides the energy for a series of electron carriers to operate together to transfer electrons and generate a transmembrane electrochemical gradient."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900653", "l": "negative regulation of demethylkotanin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of demethylkotanin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990489", "l": "anaerobic pectin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034168", "l": "negative regulation of toll-like receptor 10 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 10 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075504", "l": "macropinosomal membrane permeabilization involved in viral entry into host cell", "d": ["Induction of macropinosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus in a macropinosome, and results in release of the viral contents from the macropinosome into the host cell cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0099532", "l": "synaptic vesicle endosomal processing", "d": ["The process in which synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0030262", "l": "apoptotic nuclear changes", "d": ["Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044656", "l": "regulation of post-lysosomal vacuole size", "d": ["Any process that modulates the volume of a post-lysosomal vacuole, a membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0015887", "l": "pantothenate transmembrane transport", "d": ["The process in which pantothenate is transported across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0002675", "l": "positive regulation of acute inflammatory response", "d": ["Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "59.392451390549731", "identifiers": [{"i": "GO:0019439", "l": "aromatic compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905380", "l": "regulation of snRNA transcription by RNA polymerase II", "d": ["Any process that modulates the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0099543", "l": "trans-synaptic signaling by soluble gas", "d": ["Cell-cell signaling between presynapse and postsynapse mediated by a soluble gas ligand crossing the synaptic cleft."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.817691010327508", "identifiers": [{"i": "GO:0044283", "l": "small molecule biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.503963827996756", "identifiers": [{"i": "GO:1902533", "l": "positive regulation of intracellular signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of intracellular signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0010457", "l": "centriole-centriole cohesion", "d": ["The cell cycle process in which the two centrioles within a centrosome remain tightly paired."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0000722", "l": "telomere maintenance via recombination", "d": ["Any recombinational process that contributes to the maintenance of proper telomeric length."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990592", "l": "protein K69-linked ufmylation", "d": ["A protein ufmylation process in which a polymer of the ubiquitin-like protein UFM1 is formed by linkages between lysine residues at position 69 of the UFM1 monomers, is added to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0106070", "l": "regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903916", "l": "regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation", "d": ["Any process that modulates the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990839", "l": "response to endothelin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2001102", "l": "hexasaccharide transport", "d": ["The directed movement of a hexasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051215", "l": "RNAi-mediated antiviral immunity against DNA virus", "d": ["An RNAi-mediated post-transcriptional gene silencing pathway induced by DNA viruses leading to a sequence-specific degradation of target mRNAs or inhibition of translation. In plants, DCL3 is the primary Dicer to detect DNA viruses."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061063", "l": "positive regulation of nematode larval development", "d": ["Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071807", "l": "replication fork arrest involved in DNA replication termination", "d": ["A replication fork arrest process that contributes to the termination of DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019484", "l": "beta-alanine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903815", "l": "negative regulation of collecting lymphatic vessel constriction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of collecting lymphatic vessel constriction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030392", "l": "fructosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900535", "l": "palmitic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of palmitic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060557", "l": "positive regulation of vitamin D biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0034612", "l": "response to tumor necrosis factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0098719", "l": "sodium ion import across plasma membrane", "d": ["The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0035697", "l": "CD8-positive, alpha-beta T cell extravasation", "d": ["The migration of a CD8-positive, alpha-beta T cell from the blood vessels into the surrounding tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0035397", "l": "helper T cell enhancement of adaptive immune response", "d": ["Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901826", "l": "zeaxanthin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of zeaxanthin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099161", "l": "regulation of presynaptic dense core granule exocytosis", "d": ["Any process that modulates the frequency, rate or extent of presynaptic dense core granule exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990798", "l": "pancreas regeneration", "d": ["The regrowth of a destroyed pancreas."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098037", "l": "viral DNA genome packaging, 5' extended cos packaging", "d": ["The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 5' protruding ends."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009758", "l": "carbohydrate utilization", "d": ["A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbohydrate sources,usually glucose, and then activates genes to scavenge the last traces of the primary carbohydrate source and to transport and metabolize alternate carbohydrate sources. The utilization process begins when the cell or organism detects carbohydrate levels, includes the activation of genes whose products detect, transport or metabolize carbohydrates, and ends when the carbohydrate is incorporated into the cell or organism's metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:2000925", "l": "negative regulation of cellodextrin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046294", "l": "formaldehyde catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of formaldehyde (methanal, H2C=O), the simplest aldehyde."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032792", "l": "negative regulation of CREB transcription factor activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor CREB."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060717", "l": "chorion development", "d": ["The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050651", "l": "dermatan sulfate proteoglycan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0003418", "l": "growth plate cartilage chondrocyte differentiation", "d": ["The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090465", "l": "intracellular arginine homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of arginine within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015841", "l": "chromaffin granule amine transport", "d": ["The directed movement of amines into, out of or within chromaffin granules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010715", "l": "regulation of extracellular matrix disassembly", "d": ["Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034224", "l": "cellular response to zinc ion starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of zinc ions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006881", "l": "extracellular sequestering of iron ion", "d": ["The process of binding or confining iron ions in an extracellular area such that they are separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044473", "l": "envenomation resulting in negative regulation of calcium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a calcium channel in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071678", "l": "olfactory bulb axon guidance", "d": ["The process in which the migration of an axon growth cone of a neuron in the olfactory bulb is directed to its target in the brain in response to a combination of attractive and repulsive cues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.029717311382392", "identifiers": [{"i": "GO:0090407", "l": "organophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "48.955811371504609", "identifiers": [{"i": "GO:0003012", "l": "muscle system process", "d": ["A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060917", "l": "regulation of (1->6)-beta-D-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903057", "l": "negative regulation of melanosome organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of melanosome organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071549", "l": "cellular response to dexamethasone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0051798", "l": "positive regulation of hair follicle development", "d": ["Any process that activates or increases the frequency, rate or extent of hair follicle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051144", "l": "propanediol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of propanediol, a sweet, colorless, viscous, hygroscopic liquid with the formula CH3-CHOH-CH2OH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0050688", "l": "regulation of defense response to virus", "d": ["Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090341", "l": "negative regulation of secretion of lysosomal enzymes", "d": ["Any process that decreases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902129", "l": "(-)-lariciresinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (-)-lariciresinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036158", "l": "outer dynein arm assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046397", "l": "galacturonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of galacturonate, the anion of galacturonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.850581069382244", "identifiers": [{"i": "GO:0006672", "l": "ceramide metabolic process", "d": ["The chemical reactions and pathways involving ceramides, any N-acylated sphingoid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000453", "l": "negative regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0043941", "l": "positive regulation of sexual sporulation resulting in formation of a cellular spore", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0060079", "l": "excitatory postsynaptic potential", "d": ["A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:2000052", "l": "positive regulation of non-canonical Wnt signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of non-canonical Wnt-activated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045669", "l": "positive regulation of osteoblast differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of osteoblast differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061146", "l": "Peyer's patch morphogenesis", "d": ["The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0097106", "l": "postsynaptic density organization", "d": ["A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000943", "l": "negative regulation of amylopectin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0090022", "l": "regulation of neutrophil chemotaxis", "d": ["Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021778", "l": "oligodendrocyte cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904476", "l": "negative regulation of small GTPase binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of small GTPase binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0031295", "l": "T cell costimulation", "d": ["The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072166", "l": "posterior mesonephric tubule development", "d": ["The progression of the posterior mesonephric tubule over time, from its initial formation to the mature structure. The posterior mesonephric tubule is an epithelial tube that is part of the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140122", "l": "regulation of Lewy body formation", "d": ["Any process that modulates the frequency, rate or extent of Lewy body formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010636", "l": "positive regulation of mitochondrial fusion", "d": ["Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901711", "l": "negative regulation of homoserine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of homoserine biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0014878", "l": "response to electrical stimulus involved in regulation of muscle adaptation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.980302069293842", "identifiers": [{"i": "GO:0002699", "l": "positive regulation of immune effector process", "d": ["Any process that activates or increases the frequency, rate, or extent of an immune effector process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061807", "l": "positive regulation of DNA recombination at centromere", "d": ["Any process that activates or increases the frequency, rate or extent of DNA recombination at the centromere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042899", "l": "arabinan transmembrane transport", "d": ["The process in which arabinan is transported across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0007117", "l": "budding cell bud growth", "d": ["The process in which the bud portion of a cell that reproduces by budding irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060046", "l": "regulation of acrosome reaction", "d": ["Any process that modulates the frequency, rate or extent of the acrosome reaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0032459", "l": "regulation of protein oligomerization", "d": ["Any process that modulates the frequency, rate or extent of protein oligomerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:2000405", "l": "negative regulation of T cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904821", "l": "chloroplast disassembly", "d": ["The disaggregation of a chloroplast into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0005983", "l": "starch catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of starch, the most important reserve polysaccharide in plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.474657494018913", "identifiers": [{"i": "GO:0015749", "l": "monosaccharide transmembrane transport", "d": ["The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044517", "l": "modulation of vasoactive intestinal polypeptide receptor activity in another organism", "d": ["The process in which an organism effects a change in the activity of a vasoactive intestinal polypeptide receptor in a second organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160025", "l": "sensory perception of itch", "d": ["A sensory perception which causes the desire or reflex to scratch."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902956", "l": "regulation of mitochondrial electron transport, NADH to ubiquinone", "d": ["Any process that modulates the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901830", "l": "zeaxanthin bis(beta-D-glucoside) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of zeaxanthin bis(beta-D-glucoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0032253", "l": "dense core granule localization", "d": ["Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901557", "l": "response to fenofibrate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fenofibrate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901529", "l": "positive regulation of anion channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of anion channel activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090043", "l": "regulation of tubulin deacetylation", "d": ["Any process that modulates the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071290", "l": "cellular response to platinum ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0019594", "l": "mannitol metabolic process", "d": ["The chemical reactions and pathways involving mannitol, the alditol derived from D-mannose by reduction of the aldehyde group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902086", "l": "fumagillin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fumagillin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0072221", "l": "metanephric distal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061262", "l": "mesonephric renal vesicle formation", "d": ["The developmental process pertaining to the initial formation of the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090229", "l": "negative regulation of red or far-red light signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0030954", "l": "astral microtubule nucleation", "d": ["The 'de novo' formation of an astral microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0060260", "l": "regulation of transcription initiation by RNA polymerase II", "d": ["Any process that modulates the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0032388", "l": "positive regulation of intracellular transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0044758", "l": "modulation by symbiont of host synaptic transmission", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060882", "l": "basement membrane disassembly involved in semicircular canal fusion", "d": ["A process that results in the breakdown of the basement membrane that contributes to the process of semicircular canal fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035965", "l": "cardiolipin acyl-chain remodeling", "d": ["Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072297", "l": "specification of metanephric proximal tubule identity", "d": ["The process in which the proximal tubule of the metanephric nephron acquires its identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0002067", "l": "glandular epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106272", "l": "protein localization to ERGIC", "d": ["A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum-Golgi intermediate compartment (ERGIC)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000996", "l": "positive regulation of mannan catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of mannan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060280", "l": "negative regulation of ovulation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006172", "l": "ADP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000973", "l": "regulation of pro-B cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of pro-B cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000678", "l": "negative regulation of transcription regulatory region DNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0019229", "l": "regulation of vasoconstriction", "d": ["Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0007453", "l": "clypeo-labral disc morphogenesis", "d": ["The process in which the anatomical structures derived from the clypeo-labral disc are generated and organized. This includes the transformation of a clypeo-labal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the labrum, anterior and posterior cibarial plates, fish trap bristles, epistomal sclerite and clypeus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015877", "l": "biopterin transport", "d": ["The directed movement of biopterin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034030", "l": "ribonucleoside bisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0034759", "l": "regulation of iron ion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070316", "l": "regulation of G0 to G1 transition", "d": ["A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state to the G1 phase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0017010", "l": "protein-phycourobilin linkage", "d": ["The linkage of the chromophore phycourobilin to phycoerythrins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.967140482697559", "identifiers": [{"i": "GO:0140053", "l": "mitochondrial gene expression", "d": ["The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019101", "l": "female somatic sex determination", "d": ["The determination of sex and sexual phenotypes in a female organism's soma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904635", "l": "positive regulation of podocyte apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905516", "l": "positive regulation of fertilization", "d": ["Any process that activates or increases the frequency, rate or extent of fertilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0048265", "l": "response to pain", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0015853", "l": "adenine transport", "d": ["The directed movement of adenine, 6-aminopurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1905725", "l": "protein localization to microtubule end", "d": ["A process in which a protein is transported to, or maintained in, a location at a microtubule end."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140645", "l": "neutrophic extracellular trap formation", "d": ["The aggregation, arrangement and bonding together of a set of components to form a neutrophil extracellular trap, a network of extracellular fibers primarily composed of DNA from neutrophils, which bind and neutralizes pathogens."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044210", "l": "'de novo' CTP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902004", "l": "positive regulation of amyloid-beta formation", "d": ["Any process that activates or increases the frequency, rate or extent of amyloid-beta formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000986", "l": "negative regulation of behavioral fear response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of behavioral fear response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903404", "l": "positive regulation of renal phosphate excretion", "d": ["Any process that activates or increases the frequency, rate or extent of renal phosphate excretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0009435", "l": "NAD biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014866", "l": "skeletal myofibril assembly", "d": ["The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905300", "l": "positive regulation of intestinal epithelial cell development", "d": ["Any process that activates or increases the frequency, rate or extent of intestinal epithelial cell development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042189", "l": "vanillin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903182", "l": "regulation of SUMO transferase activity", "d": ["Any process that modulates the frequency, rate or extent of SUMO ligase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0099549", "l": "trans-synaptic signaling by carbon monoxide", "d": ["Cell-cell signaling between presynapse and postsynapse mediated by carbon monoxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033052", "l": "cyanoamino acid metabolic process", "d": ["The chemical reactions and pathways involving cyanoamino acids, amino acid derivatives that contain a cyanide group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0030950", "l": "establishment or maintenance of actin cytoskeleton polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of polarized actin-based cytoskeletal structures."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060532", "l": "bronchus cartilage development", "d": ["The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036205", "l": "histone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a histone protein by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0002001", "l": "renin secretion into blood stream", "d": ["The regulated release of renin into the blood stream by juxtoglomerular cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046082", "l": "5-methylcytosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 5-methylcytosine, a methylated base of DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048570", "l": "notochord morphogenesis", "d": ["The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071877", "l": "regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0007143", "l": "female meiotic nuclear division", "d": ["A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0046437", "l": "D-amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-amino acids, the D-enantiomers of amino acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090070", "l": "positive regulation of ribosome biogenesis", "d": ["Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007027", "l": "negative regulation of axonemal microtubule depolymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900563", "l": "dehydroaustinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dehydroaustinol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006610", "l": "ribosomal protein import into nucleus", "d": ["The directed movement of a ribosomal protein from the cytoplasm into the nucleus, across the nuclear membrane. At least some ribosomal proteins, including rpl12, uses the importin 11 pathway as a major route into the nucleus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905532", "l": "regulation of leucine import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of leucine import across plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904642", "l": "cellular response to dinitrophenol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006061", "l": "sorbitol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0051933", "l": "amino acid neurotransmitter reuptake", "d": ["The uptake of amino acid neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048160", "l": "primary follicle stage", "d": ["The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902386", "l": "glycyrrhetinate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycyrrhetinate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070078", "l": "histone H3-R2 demethylation", "d": ["The modification of histone H3 by the removal of a methyl group from arginine at position 2 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0048448", "l": "stamen morphogenesis", "d": ["The process in which the anatomical structures of the stamen are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048855", "l": "adenohypophysis morphogenesis", "d": ["The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0071243", "l": "cellular response to arsenic-containing substance", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071433", "l": "cell wall repair", "d": ["A process of cell wall organization that results in the restoration of the cell wall following damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048913", "l": "anterior lateral line nerve glial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045726", "l": "positive regulation of integrin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000955", "l": "negative regulation of cyclodextrin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cyclodextrin metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045972", "l": "negative regulation of juvenile hormone secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of juvenile hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0010594", "l": "regulation of endothelial cell migration", "d": ["Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0051513", "l": "regulation of monopolar cell growth", "d": ["Any process that modulates the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903973", "l": "negative regulation of cellular response to macrophage colony-stimulating factor stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904283", "l": "negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0015942", "l": "formate metabolic process", "d": ["The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018395", "l": "peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine", "d": ["The hydroxylation of peptidyl-lysine to peptidyl-5-hydroxy-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035706", "l": "T-helper 1 cell chemotaxis", "d": ["The directed movement of a T-helper 1 cell in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0003384", "l": "apical constriction involved in gastrulation", "d": ["The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell, contributing to the process of gastrulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0090267", "l": "positive regulation of mitotic cell cycle spindle assembly checkpoint", "d": ["Any process that increases the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033507", "l": "glucosinolate biosynthetic process from phenylalanine", "d": ["The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including phenylalanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002919", "l": "positive regulation of peripheral B cell anergy", "d": ["Any process that activates or increases the frequency, rate, or extent of peripheral B cell anergy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0018418", "l": "nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide", "d": ["The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032904", "l": "negative regulation of nerve growth factor production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of nerve growth factor (NGF)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0018366", "l": "chiral amino acid racemization", "d": ["The formation of a mixture of the two possible enantiomers from the D- or L-enantiomer of a chiral amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061430", "l": "bone trabecula morphogenesis", "d": ["The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014060", "l": "regulation of epinephrine secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of epinephrine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010920", "l": "negative regulation of inositol phosphate biosynthetic process", "d": ["Any process that decreases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090436", "l": "leaf pavement cell development", "d": ["The process whose specific outcome is the progression of an leaf pavement cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a leaf pavement cell fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009196", "l": "pyrimidine deoxyribonucleoside diphosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0106012", "l": "positive regulation of protein localization to medial cortex", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to the medial cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900309", "l": "regulation of maltoheptaose metabolic process", "d": ["Any process that modulates the frequency, rate or extent of maltoheptaose metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0021688", "l": "cerebellar molecular layer formation", "d": ["The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0031048", "l": "regulatory ncRNA-mediated heterochromatin formation", "d": ["A heterochromatin formation-based gene silencing process mediated by a regulatory non-coding RNA molecule that occur before the beginnning of trancription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071347", "l": "cellular response to interleukin-1", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "66.825956045430587", "identifiers": [{"i": "GO:0050808", "l": "synapse organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033074", "l": "pinene catabolic process", "d": ["The chemical reactions and pathways leading to the breakdown of the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0002763", "l": "positive regulation of myeloid leukocyte differentiation", "d": ["Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1901390", "l": "positive regulation of transforming growth factor beta activation", "d": ["Any process that activates or increases the frequency, rate or extent of transforming growth factor beta activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0021892", "l": "cerebral cortex GABAergic interneuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a GABAergic interneuron residing in the cerebral cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002152", "l": "bile acid conjugation", "d": ["The process in which bile acids are covalently linked to taurine or glycine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0046464", "l": "acylglycerol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0002865", "l": "negative regulation of acute inflammatory response to antigenic stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0014904", "l": "myotube cell development", "d": ["The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072702", "l": "response to methyl methanesulfonate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904277", "l": "negative regulation of wax biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of wax biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:1901658", "l": "glycosyl compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycosyl compound."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034254", "l": "regulation of urea catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of urea."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009964", "l": "negative regulation of flavonoid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902961", "l": "positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903024", "l": "positive regulation of ascospore-type prospore membrane formation", "d": ["Any process that activates or increases the frequency, rate or extent of formation of an ascospore-type prospore membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034267", "l": "discadenine metabolic process", "d": ["The chemical reactions and pathways involving discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990267", "l": "response to transition metal nanoparticle", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transition metal nanoparticle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140783", "l": "(M)-viriditoxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (M)-viriditoxin, a fungal secondary metabolite with antibacterial activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.093101469280398", "identifiers": [{"i": "GO:1901888", "l": "regulation of cell junction assembly", "d": ["Any process that modulates the frequency, rate or extent of cell junction assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0018214", "l": "protein carboxylation", "d": ["The addition of a carboxy group to a protein amino acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019853", "l": "L-ascorbic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900817", "l": "ochratoxin A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ochratoxin A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014035", "l": "neural crest cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a neural crest cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0009686", "l": "gibberellin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905693", "l": "regulation of phosphatidic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of phosphatidic acid biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0062163", "l": "pseudohyphal septin ring assembly", "d": ["The aggregation, arrangement and bonding together of septins and associated proteins to form a tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032729", "l": "positive regulation of type II interferon production", "d": ["Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015904", "l": "tetracycline transmembrane transport", "d": ["The directed movement of tetracycline from one side of a membrane to the other. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903746", "l": "positive regulation of pharyngeal pumping", "d": ["Any process that activates or increases the frequency, rate or extent of pharyngeal pumping."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904667", "l": "negative regulation of ubiquitin protein ligase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin protein ligase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001004", "l": "negative regulation of pectin catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pectin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002077", "l": "acrosome matrix dispersal", "d": ["The proteolytic digestion of components in the acrosomal matrix that occurs as part of the acrosome reaction. The process can occur either in the cumulus oophorous facilitating the penetration of it by the sperm, or at the zona pellucida allowing the sperm to reach the plasma membrane of the egg where the inner acrosomal membrane of the sperm can interact with the egg plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000399", "l": "negative regulation of thymocyte aggregation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte aggregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001156", "l": "regulation of proline catabolic process to glutamate", "d": ["Any process that modulates the frequency, rate or extent of proline catabolic process to glutamate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0039526", "l": "modulation by virus of host apoptotic process", "d": ["Any process in which a virus modulates the frequency, rate or extent of apoptosis of infected host cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031286", "l": "negative regulation of sorocarp stalk cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0097343", "l": "ripoptosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a ripoptosome, a protein complex whose formation can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.28689886973082", "identifiers": [{"i": "GO:0009967", "l": "positive regulation of signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of signal transduction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:1903464", "l": "negative regulation of mitotic cell cycle DNA replication", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900514", "l": "positive regulation of starch utilization system complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of starch utilization system complex assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.675373588411375", "identifiers": [{"i": "GO:0061531", "l": "primary amine secretion", "d": ["The regulated release of a primary amine by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0072665", "l": "protein localization to vacuole", "d": ["A process in which a protein is transported to, or maintained at, a location in a vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007383", "l": "specification of segmental identity, antennal segment", "d": ["The specification of the characteristic structures of the antennal segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0097306", "l": "cellular response to alcohol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0003318", "l": "cell migration to the midline involved in heart development", "d": ["The orderly movement of a cell toward the midline that contributes to the progression of the heart over time."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0048794", "l": "swim bladder development", "d": ["The process whose specific outcome is the progression of the swim bladder over time, from its formation to the mature structure. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072342", "l": "response to anion stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of anion stress, an increase or decrease in the concentration of negatively charged ions in the environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900491", "l": "regulation of [4Fe-4S] cluster assembly", "d": ["Any process that modulates the frequency, rate or extent of [4Fe-4S] cluster assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0043489", "l": "RNA stabilization", "d": ["Prevention of degradation of RNA molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046881", "l": "positive regulation of follicle-stimulating hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902510", "l": "regulation of apoptotic DNA fragmentation", "d": ["Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060129", "l": "thyroid-stimulating hormone-secreting cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a thyroid-stimulating hormone-secreting cell. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid-stimulating hormone, thyrotrophin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905539", "l": "regulation of postsynapse to nucleus signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of postsynapse to nucleus signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:0051147", "l": "regulation of muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of muscle cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032203", "l": "telomere formation via telomerase", "d": ["A cellular process that results in the formation of a telomere at a non-telomeric double-stranded DNA end that involves the activity of a telomerase enzyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042397", "l": "phosphagen catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0098970", "l": "postsynaptic neurotransmitter receptor diffusion trapping", "d": ["The process by which diffusing neurotransmitter receptor becomes trapped at the postsynaptic specialization membrane. This is typically due to interaction with components of the post-synaptic specialization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0030640", "l": "polyketide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0055090", "l": "acylglycerol homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of acylglycerol within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035670", "l": "plant-type ovary development", "d": ["The process whose specific outcome is the progression of an ovary that produces an ovule over time, from its formation to the mature structure. The ovary is the enlarged basal portion of a carpel and matures into a fruit. An ovule is the multicellular structure that gives rise to and contains the female reproductive cells, and develops into a seed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0034369", "l": "plasma lipoprotein particle remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0015919", "l": "peroxisomal membrane transport", "d": ["The directed movement of substances to, from or across the peroxisomal membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904610", "l": "response to 3,3',4,4',5-pentachlorobiphenyl", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0051985", "l": "negative regulation of chromosome segregation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.590029142468794", "identifiers": [{"i": "GO:0009072", "l": "aromatic amino acid metabolic process", "d": ["The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:2000178", "l": "negative regulation of neural precursor cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0006480", "l": "N-terminal protein amino acid methylation", "d": ["The methylation of the N-terminal amino acid of a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140543", "l": "positive regulation of piRNA transcription", "d": ["Any process that increases the frequency, rate or extent of the synthesis of piRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045636", "l": "positive regulation of melanocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of melanocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061963", "l": "regulation of entry into reproductive diapause", "d": ["Any process that modulates the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001033", "l": "negative regulation of double-strand break repair via nonhomologous end joining", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0016239", "l": "positive regulation of macroautophagy", "d": ["Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060501", "l": "positive regulation of epithelial cell proliferation involved in lung morphogenesis", "d": ["Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045711", "l": "positive regulation of adult salivary gland boundary specification", "d": ["Any process that activates or increases the frequency, rate or extent of salivary gland determination in an adult organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0043643", "l": "tetracycline metabolic process", "d": ["The chemical reactions and pathways involving tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905466", "l": "negative regulation of G-quadruplex DNA unwinding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA unwinding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1990867", "l": "response to gastrin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0050872", "l": "white fat cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904223", "l": "regulation of glucuronosyltransferase activity", "d": ["Any process that modulates the frequency, rate or extent of glucuronosyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032745", "l": "positive regulation of interleukin-21 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-21 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014818", "l": "skeletal muscle satellite cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.295828638494967", "identifiers": [{"i": "GO:0080135", "l": "regulation of cellular response to stress", "d": ["Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0030575", "l": "nuclear body organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of any of the extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060790", "l": "tooth placode formation", "d": ["The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0040021", "l": "hermaphrodite germ-line sex determination", "d": ["The determination of sex and sexual phenotype in the germ line of a hermaphrodite."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0002396", "l": "MHC protein complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060583", "l": "regulation of actin cortical patch localization", "d": ["Any process that modulates the localization of an actin cortical patch. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033690", "l": "positive regulation of osteoblast proliferation", "d": ["Any process that activates or increases the rate or extent of osteoblast proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0106064", "l": "regulation of cobalamin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0060114", "l": "vestibular receptor cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a vestibular hair cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0075263", "l": "oogonium development", "d": ["The process that leads to the development of an oogonium, a female gametangium of Oomycetes, containing one or more gametes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0090075", "l": "relaxation of muscle", "d": ["A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075524", "l": "ribosomal skipping", "d": ["A translation process in which a specific viral peptide prevents the ribosome from covalently linking a new inserted amino acid, and lets it continue translation, thereby cleaving the nascent protein while allowing translation to continue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001191", "l": "regulation of gamma-delta T cell activation involved in immune response", "d": ["Any process that modulates the frequency, rate or extent of gamma-delta T cell activation involved in immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905776", "l": "positive regulation of DNA helicase activity", "d": ["Any process that activates or increases the frequency, rate or extent of ATP-dependent DNA helicase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900681", "l": "octadecene metabolic process", "d": ["The chemical reactions and pathways involving octadecene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.686661695795102", "identifiers": [{"i": "GO:0098661", "l": "inorganic anion transmembrane transport", "d": ["The process in which an inorganic anion is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905119", "l": "response to haloperidol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0006702", "l": "androgen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900241", "l": "positive regulation of phenotypic switching", "d": ["Any process that activates or increases the frequency, rate or extent of phenotypic switching."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035458", "l": "cellular response to interferon-beta", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900539", "l": "fumonisin metabolic process", "d": ["The chemical reactions and pathways involving fumonisin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042103", "l": "positive regulation of T cell homeostatic proliferation", "d": ["Any process that activates or increases the rate or extent of resting T cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031037", "l": "myosin II filament disassembly", "d": ["The disassembly of a bipolar filament composed of myosin II molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071449", "l": "cellular response to lipid hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090274", "l": "positive regulation of somatostatin secretion", "d": ["Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0070943", "l": "neutrophil-mediated killing of symbiont cell", "d": ["The directed killing of a symbiont target cell by a neutrophil. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035217", "l": "labial disc development", "d": ["Progression of the labial imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including parts of the proboscis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0090629", "l": "lagging strand initiation", "d": ["The process in which the synthesis of DNA from a template strand in a net 3' to 5' direction is started."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035233", "l": "germ cell repulsion", "d": ["The directed movement of a germ cell from their site of production to the gonad, through the repulsion of cells away from a tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0010412", "l": "mannan metabolic process", "d": ["The chemical reactions and pathways involving mannan, a group of polysaccharides containing a backbone composed of a polymer of D-mannose units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090054", "l": "regulation of silent mating-type cassette heterochromatin formation", "d": ["Any process that modulates the frequency, rate, or extent of heterochromatin formation at silent mating-type cassette."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043311", "l": "positive regulation of eosinophil degranulation", "d": ["Any process that activates or increases the frequency, rate or extent of eosinophil degranulation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901936", "l": "beta-caryophyllene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of beta-caryophyllene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140727", "l": "siRNA-dependent pericentric heterochromatin formation", "d": ["The formation of pericentric heterochromatin by a process mediated by a small interfering RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072095", "l": "regulation of branch elongation involved in ureteric bud branching", "d": ["Any process that modulates the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0090386", "l": "phagosome maturation involved in apoptotic cell clearance", "d": ["A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell and contributes to apoptotic cell clearance. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071224", "l": "cellular response to peptidoglycan", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035222", "l": "wing disc pattern formation", "d": ["The process giving rise to the pattern of cell differentiation in the wing imaginal disc."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061088", "l": "regulation of sequestering of zinc ion", "d": ["Any process that modulates the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002799", "l": "positive regulation of antibacterial peptide secretion", "d": ["Any process that activates or increases the frequency, rate, or extent of antibacterial peptide secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.569439710577498", "identifiers": [{"i": "GO:0022900", "l": "electron transport chain", "d": ["A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0044630", "l": "modulation of complement activation, lectin pathway in another organism", "d": ["A process that modulates the frequency, rate or extent of the lectin pathway of complement activation, in a different organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001780", "l": "neutrophil homeostasis", "d": ["The process of regulating the proliferation and elimination of neutrophils such that the total number of neutrophils within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0048915", "l": "posterior lateral line system development", "d": ["The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000720", "l": "pyrimidine dimer repair by nucleotide-excision repair", "d": ["The repair of UV-induced T-T, C-T, and C-C dimers by the recognition and removal of the damaged DNA strand from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046587", "l": "positive regulation of calcium-dependent cell-cell adhesion", "d": ["Any process that activates or increases the frequency, rate or extent of calcium-dependent cell-cell adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072719", "l": "cellular response to cisplatin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0048099", "l": "anterior/posterior lineage restriction, imaginal disc", "d": ["Formation and/or maintenance of a lineage boundary between anterior and posterior compartments that cells cannot cross, thus separating the populations of cells in each compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0000958", "l": "mitochondrial mRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mRNA transcribed from the mitochondrial genome and occurring in the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905854", "l": "negative regulation of heparan sulfate binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001410", "l": "chlamydospore formation", "d": ["The process whose specific outcome is the progression of the chlamydospore over time, from its formation to the mature structure. A chlamydospores is a mitotic (asexual) one-celled spore, produced primarily for survival, not dispersal, originating endogenously and singly within part of a pre-existing cell and possessing an inner secondary and often thickened cell wall. An example of this is found in Candida albicans."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0008652", "l": "amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048135", "l": "female germ-line cyst formation", "d": ["Formation of a group of interconnected cells derived from a single female gonial founder cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0015735", "l": "uronic acid transmembrane transport", "d": ["The process in which uronic acid is transported across a lipid bilayer, from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903935", "l": "response to sodium arsenite", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0099614", "l": "protein localization to spore cell wall", "d": ["A process in which a protein is transported, tethered to or otherwise maintained in a spore cell wall."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0046134", "l": "pyrimidine nucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060531", "l": "neuroendocrine cell differentiation involved in prostate gland acinus development", "d": ["The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904007", "l": "positive regulation of phospholipase D activity", "d": ["Any process that activates or increases the frequency, rate or extent of phospholipase D activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035698", "l": "CD8-positive, alpha-beta cytotoxic T cell extravasation", "d": ["The migration of a CD8-positive, alpha-beta cytotoxic T cell from the blood vessels into the surrounding tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2001248", "l": "regulation of ammonia assimilation cycle", "d": ["Any process that modulates the frequency, rate or extent of ammonia assimilation cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900983", "l": "vindoline metabolic process", "d": ["The chemical reactions and pathways involving vindoline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901076", "l": "positive regulation of engulfment of apoptotic cell", "d": ["Any process that activates or increases the frequency, rate or extent of engulfment of apoptotic cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140923", "l": "magnetosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a magnetosome. Magnetosomes are specialized organelles for magnetic navigation that comprise membrane-enveloped, nano-sized crystals of a magnetic iron mineral; they are formed by a diverse group of magnetotactic bacteria (MTB)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905902", "l": "regulation of mesoderm formation", "d": ["Any process that modulates the frequency, rate or extent of mesoderm formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033632", "l": "regulation of cell-cell adhesion mediated by integrin", "d": ["Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0042984", "l": "regulation of amyloid precursor protein biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.155424086811493", "identifiers": [{"i": "GO:0016447", "l": "somatic recombination of immunoglobulin gene segments", "d": ["The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0048390", "l": "intermediate mesoderm morphogenesis", "d": ["The process in which the anatomical structures of the intermediate mesoderm are generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061069", "l": "male urethra development", "d": ["The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046938", "l": "phytochelatin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010988", "l": "regulation of low-density lipoprotein particle clearance", "d": ["Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0036314", "l": "response to sterol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0030202", "l": "heparin metabolic process", "d": ["The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010167", "l": "response to nitrate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0001936", "l": "regulation of endothelial cell proliferation", "d": ["Any process that modulates the frequency, rate, or extent of endothelial cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.166077096831089", "identifiers": [{"i": "GO:0060973", "l": "cell migration involved in heart development", "d": ["The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0014012", "l": "peripheral nervous system axon regeneration", "d": ["The regrowth of axons outside the central nervous system (outside the brain and spinal cord) following an axonal injury."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0031987", "l": "locomotion involved in locomotory behavior", "d": ["Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901006", "l": "ubiquinone-6 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ubiquinone-6."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090081", "l": "regulation of heart induction by regulation of canonical Wnt signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of canonical Wnt signaling pathway that regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, followed by relaying of the signal via beta-catenin, and ending with a change in transcription of target genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090378", "l": "seed trichome elongation", "d": ["The process in which a seed trichome irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0043386", "l": "mycotoxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0035442", "l": "dipeptide transmembrane transport", "d": ["The directed movement of a dipeptide across a membrane by means of some agent such as a transporter or pore. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2001056", "l": "positive regulation of cysteine-type endopeptidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.598265520774746", "identifiers": [{"i": "GO:0043085", "l": "positive regulation of catalytic activity", "d": ["Any process that activates or increases the activity of an enzyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043108", "l": "pilus retraction", "d": ["The process of withdrawing a pilus back into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.990900157612501", "identifiers": [{"i": "GO:0002088", "l": "lens development in camera-type eye", "d": ["The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904216", "l": "positive regulation of protein import into chloroplast stroma", "d": ["Any process that activates or increases the frequency, rate or extent of protein import into chloroplast stroma."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904581", "l": "negative regulation of intracellular mRNA localization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intracellular mRNA localization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904798", "l": "positive regulation of core promoter binding", "d": ["Any process that activates or increases the frequency, rate or extent of core promoter binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.920089577627991", "identifiers": [{"i": "GO:0097194", "l": "execution phase of apoptosis", "d": ["A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0006613", "l": "cotranslational protein targeting to membrane", "d": ["The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the endoplasmic reticulum lumen occurs in this manner, as does the import of some proteins into mitochondria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060668", "l": "regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling", "d": ["Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the extracellular matrix to the epithelium of the salivary gland."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903452", "l": "positive regulation of G1 to G0 transition", "d": ["Any process that activates or increases the frequency, rate or extent of G1 to G0 transition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070512", "l": "positive regulation of histone H4-K20 methylation", "d": ["Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:1905521", "l": "regulation of macrophage migration", "d": ["Any process that modulates the frequency, rate or extent of macrophage migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0060601", "l": "lateral sprouting from an epithelium", "d": ["The process in which a branch forms along the side of an epithelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.314728742240533", "identifiers": [{"i": "GO:0030595", "l": "leukocyte chemotaxis", "d": ["The movement of a leukocyte in response to an external stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070468", "l": "dentin extracellular matrix secretion", "d": ["The regulated release by odontoblasts of the extracellular matrix constituents, including collagen, that form the basis of dentin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903659", "l": "regulation of complement-dependent cytotoxicity", "d": ["Any process that modulates the frequency, rate or extent of complement-dependent cytotoxicity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001076", "l": "positive regulation of metanephric ureteric bud development", "d": ["Any process that activates or increases the frequency, rate or extent of metanephric ureteric bud development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033123", "l": "positive regulation of purine nucleotide catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0089706", "l": "L-ornithine transmembrane export from vacuole", "d": ["The directed movement of L-ornithine out of the vacuole, across the vacuolar membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900846", "l": "regulation of naphtho-gamma-pyrone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904801", "l": "positive regulation of neuron remodeling", "d": ["Any process that activates or increases the frequency, rate or extent of neuron remodeling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0061975", "l": "articular cartilage development", "d": ["The process whose specific outcome is the progression of articular cartilage over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032354", "l": "response to follicle-stimulating hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060319", "l": "primitive erythrocyte differentiation", "d": ["Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0001710", "l": "mesodermal cell fate commitment", "d": ["The cell differentiation process that results in commitment of a cell to become part of the mesoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901436", "l": "positive regulation of toluene catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of toluene catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031950", "l": "negative regulation of glucocorticoid catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903897", "l": "regulation of PERK-mediated unfolded protein response", "d": ["Any process that modulates the frequency, rate or extent of the PERK-mediated unfolded protein response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1903069", "l": "regulation of ER-associated ubiquitin-dependent protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015876", "l": "acetyl-CoA transport", "d": ["The directed movement of acetyl-CoA into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0033376", "l": "establishment of protein localization to T cell secretory granule", "d": ["The directed movement of a protein to a location within a secretory granule in a T cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0002719", "l": "negative regulation of cytokine production involved in immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.415093686714229", "identifiers": [{"i": "GO:0031365", "l": "N-terminal protein amino acid modification", "d": ["The alteration of the N-terminal amino acid residue in a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060431", "l": "primary lung bud formation", "d": ["The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051975", "l": "lysine biosynthetic process via alpha-aminoadipate and saccharopine", "d": ["The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and saccharopine. This pathway is used by yeast and fungi to synthesize the essential amino acid L-lysine, and pathway intermediates are often incorporated into secondary metabolic processes. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This is then reduced to form alpha-aminoadipate 6-semialdehyde, which is metabolized to saccharopine and finally L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:2000573", "l": "positive regulation of DNA biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000343", "l": "positive regulation of chemokine (C-X-C motif) ligand 2 production", "d": ["Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.053789595961774", "identifiers": [{"i": "GO:0007346", "l": "regulation of mitotic cell cycle", "d": ["Any process that modulates the rate or extent of progress through the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090346", "l": "cellular organofluorine metabolic process", "d": ["The chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1903421", "l": "regulation of synaptic vesicle recycling", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle recycling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050992", "l": "dimethylallyl diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901713", "l": "negative regulation of urea catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of urea catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035892", "l": "modulation of platelet aggregation in another organism", "d": ["Any process in which an organism modulates the frequency, rate or extent of platelet aggregation in another organism. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903461", "l": "Okazaki fragment processing involved in mitotic DNA replication", "d": ["Any DNA replication, Okazaki fragment processing that is involved in mitotic cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1905613", "l": "regulation of developmental vegetative growth", "d": ["Any process that modulates the frequency, rate or extent of developmental vegetative growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901883", "l": "4-hydroxycoumarin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 4-hydroxycoumarin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045808", "l": "negative regulation of establishment of competence for transformation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of competence for transformation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001967", "l": "suckling behavior", "d": ["Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.004672668108633", "identifiers": [{"i": "GO:1901700", "l": "response to oxygen-containing compound", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098759", "l": "cellular response to interleukin-8", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902549", "l": "protein localization to Mei2 nuclear dot", "d": ["A process in which a protein is transported to, or maintained in, a location within a Mei2 nuclear dot."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006777", "l": "Mo-molybdopterin cofactor biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070874", "l": "negative regulation of glycogen metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900130", "l": "regulation of lipid binding", "d": ["Any process that modulates the frequency, rate or extent of lipid binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072722", "l": "response to amitrole", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014899", "l": "cardiac muscle atrophy", "d": ["A process, occurring in the heart, in which a decrease in cell mass and then in heart size occurs due to shrinking of the individual cells. The shrinkage is caused by protein degradation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009222", "l": "pyrimidine ribonucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901371", "l": "regulation of leaf morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of leaf morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051900", "l": "regulation of mitochondrial depolarization", "d": ["Any process that modulates the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072296", "l": "specification of metanephric loop of Henle identity", "d": ["The process in which the loop of Henle of the metanephric nephron acquires its identity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061502", "l": "early endosome to recycling endosome transport", "d": ["The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the recycling endosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002500", "l": "proteolysis within lysosome associated with antigen processing and presentation", "d": ["The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048159", "l": "primary oocyte stage", "d": ["The stage in oogenesis when the oocyte has a nucleus slightly larger than those of the adjacent cells and is surrounded by a layer of loose squamous epithelial cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072195", "l": "kidney smooth muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1900599", "l": "demethylkotanin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of demethylkotanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032902", "l": "nerve growth factor production", "d": ["The appearance of nerve growth factor (NGF) due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0060224", "l": "regulation of retinal rod cell fate commitment", "d": ["Any process that modulates the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048088", "l": "regulation of male pigmentation", "d": ["Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in males."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090168", "l": "Golgi reassembly", "d": ["The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0090101", "l": "negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway", "d": ["Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904637", "l": "cellular response to ionomycin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902197", "l": "isovaleryl-CoA(4-) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isovaleryl-CoA(4-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0099187", "l": "presynaptic cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071642", "l": "positive regulation of macrophage inflammatory protein 1 alpha production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072464", "l": "response to meiotic spindle assembly checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of meiotic spindle assembly checkpoint signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902448", "l": "positive regulation of shade avoidance", "d": ["Any process that activates or increases the frequency, rate or extent of shade avoidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000210", "l": "positive regulation of anoikis", "d": ["Any process that activates or increases the frequency, rate or extent of anoikis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006235", "l": "dTTP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0034770", "l": "histone H4-K20 methylation", "d": ["The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0006388", "l": "tRNA splicing, via endonucleolytic cleavage and ligation", "d": ["Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.000891501185137", "identifiers": [{"i": "GO:0000271", "l": "polysaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010624", "l": "regulation of Schwann cell proliferation", "d": ["Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001131", "l": "methane biosynthetic process from dimethyl sulfide", "d": ["The chemical reactions and pathways resulting in the formation of a methane from a dimethyl sulfide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904733", "l": "negative regulation of electron transfer activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of electron transfer activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007014", "l": "actin ubiquitination", "d": ["The modification of actin by addition of ubiquitin groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0030450", "l": "regulation of complement activation, classical pathway", "d": ["Any process that modulates the frequency, rate or extent of the classical pathway of complement activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "58.151924274517057", "identifiers": [{"i": "GO:0050790", "l": "regulation of catalytic activity", "d": ["Any process that modulates the activity of an enzyme."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045114", "l": "beta 2 integrin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta 2 integrins, a subfamily of integrins which contain the beta 2 subunit."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.098124162625822", "identifiers": [{"i": "GO:0072659", "l": "protein localization to plasma membrane", "d": ["A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035483", "l": "gastric emptying", "d": ["The process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0039533", "l": "regulation of MDA-5 signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:0008156", "l": "negative regulation of DNA replication", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032215", "l": "positive regulation of telomere maintenance via semi-conservative replication", "d": ["Any process that activates or increases the frequency, rate or extent of the semi-conservative replication of telomeric DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141030", "l": "perturbation by symbiont of host actin cytoskeleton via filamentous actin depolymerization", "d": ["The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by depolymerizing the host filamentous actin. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900851", "l": "positive regulation of pseurotin A biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of pseurotin A biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0090387", "l": "phagolysosome assembly involved in apoptotic cell clearance", "d": ["The process in which a phagosome, a vesicle formed by phagocytosis, fuses with a lysosome as a part of apoptotic cell clearance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0035634", "l": "response to stilbenoid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903435", "l": "positive regulation of constitutive secretory pathway", "d": ["Any process that activates or increases the frequency, rate or extent of constitutive secretory pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0080168", "l": "abscisic acid transport", "d": ["The directed movement of abscisic acid into, out of, within or between cells by means of some external agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045647", "l": "negative regulation of erythrocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045049", "l": "protein insertion into ER membrane by N-terminal cleaved signal sequence", "d": ["A process of protein insertion into the endoplasmic reticulum (ER) membrane in which N-terminal cleaved signal sequences direct polypeptides to the ER."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.274502573267668", "identifiers": [{"i": "GO:0090183", "l": "regulation of kidney development", "d": ["Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901249", "l": "regulation of lung goblet cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of lung goblet cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000415", "l": "positive regulation of fibronectin-dependent thymocyte migration", "d": ["Any process that activates or increases the frequency, rate or extent of fibronectin-dependent thymocyte migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990390", "l": "protein K33-linked ubiquitination", "d": ["A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is added to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000755", "l": "positive regulation of sphingomyelin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of sphingomyelin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900497", "l": "regulation of butyryl-CoA catabolic process to butanol", "d": ["Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.465174152298118", "identifiers": [{"i": "GO:0000279", "l": "M phase", "d": ["A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019343", "l": "cysteine biosynthetic process via cystathionine", "d": ["The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate cystathionine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034199", "l": "activation of protein kinase A activity", "d": ["Any process that initiates the activity of the inactive enzyme protein kinase A."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0060312", "l": "regulation of blood vessel remodeling", "d": ["Any process that modulates the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070414", "l": "trehalose metabolism in response to heat stress", "d": ["The chemical reactions and pathways involving trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0051667", "l": "establishment of plastid localization", "d": ["The directed movement of a plastid to a specific location in the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.261443428098588", "identifiers": [{"i": "GO:0002705", "l": "positive regulation of leukocyte mediated immunity", "d": ["Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031385", "l": "regulation of termination of mating projection growth", "d": ["Any process that modulates the frequency, rate, or extent of the end of mating projection formation by unicellular fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.170973648324292", "identifiers": [{"i": "GO:1903509", "l": "liposaccharide metabolic process", "d": ["The chemical reactions and pathways involving liposaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0015767", "l": "lactose transport", "d": ["The directed movement of lactose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090178", "l": "regulation of establishment of planar polarity involved in neural tube closure", "d": ["Any process that modulates the rate, frequency, or extent of the establishment of planar polarity involved in neural tube closure, the coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043131", "l": "erythrocyte enucleation", "d": ["The process in which nucleated precursor cells lose their nucleus during erythrocyte maturation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0045765", "l": "regulation of angiogenesis", "d": ["Any process that modulates the frequency, rate or extent of angiogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045053", "l": "protein retention in Golgi apparatus", "d": ["The retention of proteins within the Golgi apparatus. Golgi-localized carbohydrate-modifying enzymes have a short N-terminal domain that faces the cytosol, a single transmembrane alpha helix, and a large C-terminal domain that faces the Golgi lumen and that contains the catalytic site. How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0051228", "l": "mitotic spindle disassembly", "d": ["The controlled breakdown of the spindle during a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2001001", "l": "negative regulation of xylan catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of xylan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046075", "l": "dTTP metabolic process", "d": ["The chemical reactions and pathways involving dTTP, deoxyribosylthymine triphosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0071973", "l": "bacterial-type flagellum-dependent cell motility", "d": ["Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010618", "l": "aerenchyma formation", "d": ["The process that gives rise to aerenchyma, parenchyma tissue containing particularly large intercellular spaces of schizogenous or lysigenous origin. This process pertains to the initial formation of a structure from unspecified parts."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904230", "l": "negative regulation of succinate dehydrogenase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of succinate dehydrogenase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0090322", "l": "regulation of superoxide metabolic process", "d": ["Any process that modulates the rate, frequency, or extent of superoxide metabolism, the chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.686661695795102", "identifiers": [{"i": "GO:0019216", "l": "regulation of lipid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0015826", "l": "threonine transport", "d": ["The directed movement of threonine, (2R*,3S*)-2-amino-3-hydroxybutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0098953", "l": "receptor diffusion trapping", "d": ["The process by which a membrane receptor, diffusing freely within the plasma membeane, becomes trapped in some plasma membrane region. This can happen when a receptor bind, directly or indirectly, to some component of the underlying matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0071221", "l": "cellular response to bacterial lipopeptide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0033015", "l": "tetrapyrrole catabolic process", "d": ["The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.672305786814945", "identifiers": [{"i": "GO:0006006", "l": "glucose metabolic process", "d": ["The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035437", "l": "maintenance of protein localization in endoplasmic reticulum", "d": ["Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072138", "l": "mesenchymal cell proliferation involved in ureteric bud development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.594043123901756", "identifiers": [{"i": "GO:0042246", "l": "tissue regeneration", "d": ["The regrowth of lost or destroyed tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036151", "l": "phosphatidylcholine acyl-chain remodeling", "d": ["Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019604", "l": "toluene oxidation to catechol", "d": ["The formation from toluene of catechol, dihydroxybenzene, by successive oxidations followed by loss of carbon dioxide (CO2)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.863640214551324", "identifiers": [{"i": "GO:0046460", "l": "neutral lipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003201", "l": "epithelial to mesenchymal transition involved in coronary vasculature morphogenesis", "d": ["A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the shaping of the coronary vasculature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042250", "l": "maintenance of polarity of embryonic epithelium", "d": ["The maintenance of an established polarized embryonic epithelial sheet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.358732272612386", "identifiers": [{"i": "GO:0042537", "l": "benzene-containing compound metabolic process", "d": ["The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903244", "l": "positive regulation of cardiac muscle hypertrophy in response to stress", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac muscle hypertrophy in response to stress."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036484", "l": "trunk neural crest cell migration", "d": ["The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010826", "l": "negative regulation of centrosome duplication", "d": ["Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0001919", "l": "regulation of receptor recycling", "d": ["Any process that modulates the frequency, rate, or extent of receptor recycling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002416", "l": "IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor", "d": ["The process of transporting IgG immunoglobulin, via transcytosis using the FcRn (also known as the neonatal Fc receptor; gene name FCGRT), from apical surface of an epithelial cell to the basolateral surface or vice versa depending on the location. This process is used for uptake of IgG from the milk in the gut in rodents, for transplacental transport of IgG from mother to embryo in humans, and for maintenance of a steady-state distribution of IgG across epithelial boundaries in general in adult mammals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0100011", "l": "positive regulation of fever generation by prostaglandin secretion", "d": ["Any prostaglandin secretion process that positively_regulates fever generation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048781", "l": "regulation of cyanophore differentiation", "d": ["Any process that modulates the frequency, rate or extent of cyanophore differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900236", "l": "positive regulation of Kit signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of Kit signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902896", "l": "terminal web assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a terminal web."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070133", "l": "negative regulation of mitochondrial translational initiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0036507", "l": "protein demannosylation", "d": ["The removal of one or more mannose residues from a mannosylated protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021750", "l": "vestibular nucleus development", "d": ["The process whose specific outcome is the progression of the vestibular nucleus over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048006", "l": "antigen processing and presentation, endogenous lipid antigen via MHC class Ib", "d": ["The process in which an antigen-presenting cell expresses lipid antigen of endogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900001", "l": "negative regulation of anthocyanin catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anthocyanin catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0003313", "l": "heart rudiment development", "d": ["The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097737", "l": "acquisition of mycelium reproductive competence", "d": ["A maturation process by which an organism acquires the ability to reproduce. In fungi, reproductive competence only occurs in a population of filamentous cells that form a mycelium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0050655", "l": "dermatan sulfate proteoglycan metabolic process", "d": ["The chemical reactions and pathways involving dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000064", "l": "regulation of cortisol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of cortisol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002192", "l": "IRES-dependent translational initiation of linear mRNA", "d": ["The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060857", "l": "establishment of glial blood-brain barrier", "d": ["Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000868", "l": "negative regulation of estrone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of estrone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043469", "l": "regulation of D-xylose catabolic process", "d": ["Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of xylose."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061089", "l": "negative regulation of sequestering of zinc ion", "d": ["Any process that decreases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.945916858897462", "identifiers": [{"i": "GO:0007029", "l": "endoplasmic reticulum organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.369838362782886", "identifiers": [{"i": "GO:0021954", "l": "central nervous system neuron development", "d": ["The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902191", "l": "2-methylbutanoyl-CoA(4-) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 2-methylbutanoyl-CoA(4-)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0006103", "l": "2-oxoglutarate metabolic process", "d": ["The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000641", "l": "regulation of early endosome to late endosome transport", "d": ["Any process that modulates the frequency, rate or extent of early endosome to late endosome transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000470", "l": "positive regulation of peroxidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of peroxidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010032", "l": "meiotic chromosome condensation", "d": ["Compaction of chromatin structure prior to meiosis in eukaryotic cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072179", "l": "nephric duct formation", "d": ["The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003255", "l": "endocardial precursor cell differentiation", "d": ["The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of an endocardial precursor cell. A endocardial precursor cell is a cell that has been committed to a endocardial cell fate, but will undergo further cell divisions rather than terminally differentiate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903221", "l": "regulation of mitotic recombination-dependent replication fork processing", "d": ["Any process that modulates the frequency, rate or extent of mitotic recombination-dependent replication fork processing. Regulation of mitotic recombination prevents recombination between inappropriate homologous sequences."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.722653756574275", "identifiers": [{"i": "GO:0045229", "l": "external encapsulating structure organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018292", "l": "molybdenum incorporation via L-cysteinyl molybdopterin", "d": ["The incorporation of molybdenum into a protein via L-cysteinyl molybdopterin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110121", "l": "gamma-tubulin complex localization to cytoplasmic side of mitotic spindle pole body", "d": ["Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the cytoplasmic side of the mitotic spindle pole body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032765", "l": "positive regulation of mast cell cytokine production", "d": ["Any process that activates or increases the frequency, rate, or extent of mast cell cytokine production."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070933", "l": "histone H4 deacetylation", "d": ["The modification of histone H4 by the removal of one or more acetyl groups."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:2000127", "l": "positive regulation of octopamine or tyramine signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of octopamine or tyramine signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0045916", "l": "negative regulation of complement activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000371", "l": "regulation of DNA topoisomerase (ATP-hydrolyzing) activity", "d": ["Any process that modulates the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0015866", "l": "ADP transport", "d": ["The directed movement of ADP, adenosine diphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034355", "l": "NAD salvage", "d": ["Any process that generates nicotinamide adenine dinucleotide (NAD) from derivatives of it, without de novo synthesis; salvage is usually from the degradation products nicotinic acid (Na) and nicotinamide (Nam)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901481", "l": "L-glutamate import involved in cellular response to nitrogen starvation", "d": ["Any L-glutamate import that is involved in cellular response to nitrogen starvation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903473", "l": "positive regulation of mitotic actomyosin contractile ring contraction", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0001983", "l": "baroreceptor response to increased systemic arterial blood pressure", "d": ["The increase in nerve impulses from baroreceptors as a result of increased pressure on an artery that results in an inhibition of sympathetic nerve impulses to peripheral blood vessels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031148", "l": "DIF-1 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0021636", "l": "trigeminal nerve morphogenesis", "d": ["The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0072592", "l": "oxygen metabolic process", "d": ["The chemical reactions and pathways involving diatomic oxygen (O2)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902605", "l": "heterotrimeric G-protein complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a heterotrimeric G-protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0001945", "l": "lymph vessel development", "d": ["The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900147", "l": "regulation of Schwann cell migration", "d": ["Any process that modulates the frequency, rate or extent of Schwann cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0043605", "l": "amide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901924", "l": "positive regulation of sclerotium development", "d": ["Any process that activates or increases the frequency, rate or extent of sclerotium development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018072", "l": "peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine biosynthetic process from peptidyl-glutamic acid", "d": ["The modification of peptidyl-glutamic acid residues by the covalent attachment of ethanolamine, itself further modified by the addition of a phosphoglycerol unit."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902489", "l": "hepatoblast apoptotic process", "d": ["Any apoptotic process in a hepatoblast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045612", "l": "positive regulation of hemocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of hemocyte differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0009202", "l": "deoxyribonucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0021528", "l": "commissural neuron differentiation in spinal cord", "d": ["The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of commissural neurons. Commissural neurons in both vertebrates and invertebrates transfer information from one side of their bodies to the other through the midline. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043609", "l": "regulation of carbon utilization", "d": ["Any process that modulates the frequency, rate, or extent of carbon utilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1901271", "l": "lipooligosaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipooligosaccharide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900384", "l": "regulation of flavonol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of flavonol biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044205", "l": "'de novo' UMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD+ or oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:1903307", "l": "positive regulation of regulated secretory pathway", "d": ["Any process that activates or increases the frequency, rate or extent of regulated secretory pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010541", "l": "acropetal auxin transport", "d": ["The unidirectional movement of auxin from the base towards the apex of an organ, including the shoot, leaf, primary root, or lateral root."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071408", "l": "cellular response to cycloalkane", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0051177", "l": "meiotic sister chromatid cohesion", "d": ["The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990974", "l": "actin-dependent nuclear migration", "d": ["The process whereby the centrosome is held at the cell center while the nucleus moves to the cell rear by actin retrograde flow resulting in the position of the centrosome between the nucleus and the leading edge of the cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048169", "l": "regulation of long-term neuronal synaptic plasticity", "d": ["A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098996", "l": "disruption of host cell glycocalyx during viral entry", "d": ["The disruption of host cell glycocalyx by viral proteins during virus entry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032264", "l": "IMP salvage", "d": ["Any process which produces inosine monophosphate from derivatives of it, without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900146", "l": "negative regulation of nodal signaling pathway involved in determination of left/right asymmetry", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0061611", "l": "mannose to fructose-6-phosphate metabolic process", "d": ["The chemical reactions and pathways in which mannose, the aldohexose manno-hexose, is converted to fructose-6-phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106077", "l": "histone succinylation", "d": ["The modification of a histone by the addition of an succinyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048324", "l": "regulation of axial mesodermal cell fate determination", "d": ["Any process that modulates the frequency, rate or extent of axial mesoderm cell fate determination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045338", "l": "farnesyl diphosphate metabolic process", "d": ["The chemical reactions and pathways involving farnesyl diphosphate, an intermediate in carotenoid, sesquiterpene, squalene and sterol biosynthesis, as well as a substrate in protein farnesylation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014859", "l": "negative regulation of skeletal muscle cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903200", "l": "positive regulation of L-dopa decarboxylase activity", "d": ["Any process that activates or increases the frequency, rate or extent of L-dopa decarboxylase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071477", "l": "cellular hypotonic salinity response", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006962", "l": "male-specific antibacterial humoral response", "d": ["An immune response against bacteria, specific to males and mediated through a body fluid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0070168", "l": "negative regulation of biomineral tissue development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904407", "l": "positive regulation of nitric oxide metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of nitric oxide metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900721", "l": "positive regulation of uterine smooth muscle relaxation", "d": ["Any process that activates or increases the frequency, rate or extent of uterine smooth muscle relaxation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0042628", "l": "mating plug formation", "d": ["The deposition of a plug of sperm or other gelatinous material into the opening of the vulva by a male at the termination of copulation. Probably acts to prevent subsequent matings by other males."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903068", "l": "positive regulation of protein localization to cell tip", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to cell tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070796", "l": "regulation of cleistothecium development", "d": ["Any process that modulates the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000131", "l": "regulation of tyramine signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of tyramine signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060625", "l": "regulation of protein deneddylation", "d": ["Any process that modulates the rate, frequency, or extent of protein deneddylation, the removal of a ubiquitin-like protein of the NEDD8 type from a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019501", "l": "arsonoacetate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of arsonoacetate, a synthetic, organic compound containing a single arsenic atom."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048557", "l": "embryonic digestive tract morphogenesis", "d": ["The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0046535", "l": "detection of chemical stimulus involved in sensory perception of umami taste", "d": ["The series of events required for a umami taste stimulus to be received and converted to a molecular signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0032912", "l": "negative regulation of transforming growth factor beta2 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta2."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019879", "l": "peptidyl-thyronine biosynthetic process from peptidyl-tyrosine", "d": ["The formation of peptidyl-thyronine from peptidyl-tyrosine in thyroglobulin by phenyl transfer coupled with the formation of peptidyl-dehydroalanine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905007", "l": "positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation", "d": ["Any process that activates or increases the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035362", "l": "protein-DNA ISRE complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex, in which the complex is formed through interaction of the protein(s) with a interferon-stimulated response element (ISRE) in the DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002671", "l": "negative regulation of B cell anergy", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell anergy."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045695", "l": "negative regulation of embryo sac egg cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac egg cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006599", "l": "phosphagen metabolic process", "d": ["The chemical reactions and pathways involving phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140736", "l": "positive regulation of lovastatin biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of lovastin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.240853996207278", "identifiers": [{"i": "GO:1904659", "l": "glucose transmembrane transport", "d": ["The process in which glucose is transported across a membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:1990822", "l": "basic amino acid transmembrane transport", "d": ["The directed movement of basic amino acids from one side of a membrane to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904474", "l": "cellular response to L-dopa", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010226", "l": "response to lithium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903454", "l": "regulation of androst-4-ene-3,17-dione biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019386", "l": "methanogenesis, from carbon dioxide", "d": ["The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other compounds, including carbon dioxide (CO2)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.179166783752436", "identifiers": [{"i": "GO:0021587", "l": "cerebellum morphogenesis", "d": ["The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills."]}]}
{"type": "biolink:BiologicalProcess", "ic": "72.06379513530257", "identifiers": [{"i": "GO:0009063", "l": "amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0033058", "l": "directional locomotion", "d": ["Self-propelled movement of a cell or organism from one location to another along an axis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009969", "l": "xyloglucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of xyloglucan, the cross-linking glycan composed of (1->4)-beta-D glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.74456172809515", "identifiers": [{"i": "GO:0045861", "l": "negative regulation of proteolysis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043382", "l": "positive regulation of memory T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of memory T cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034628", "l": "'de novo' NAD biosynthetic process from aspartate", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.444551060876734", "identifiers": [{"i": "GO:0009266", "l": "response to temperature stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015818", "l": "isoleucine transport", "d": ["The directed movement of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900938", "l": "regulation of (Z)-nonadeca-1,14-diene metabolic process", "d": ["Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034160", "l": "negative regulation of toll-like receptor 8 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 8 signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070659", "l": "inner ear sensory epithelium regeneration", "d": ["The regrowth of lost or destroyed inner ear sensory epithelia."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048825", "l": "cotyledon development", "d": ["The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0106058", "l": "positive regulation of calcineurin-mediated signaling", "d": ["Any process that activates or increases the frequency, rate or extent of calcineurin-mediated signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0120169", "l": "detection of cold stimulus involved in thermoception", "d": ["The series of events in which a cold stimulus is received and converted into a molecular signal as part of thermoception."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071235", "l": "cellular response to proline", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1904700", "l": "granulosa cell apoptotic process", "d": ["Any apoptotic process in a granulosa cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045147", "l": "regulation of initiation of acetate catabolic process by acetate", "d": ["Any process that modulates the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000938", "l": "positive regulation of cellotriose catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellotriose catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060062", "l": "Spemann organizer formation at the dorsal lip of the blastopore", "d": ["Formation of the specialized region at the dorsal lip of the blatopore of the embryo that acts as the main signaling center establishing the vertebrate body plan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900928", "l": "positive regulation of L-threonine import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of L-threonine import into cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.839897517610368", "identifiers": [{"i": "GO:0007286", "l": "spermatid development", "d": ["The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042468", "l": "klinokinesis", "d": ["The movement of a cell or organism in response to a stimulus in which the frequency or magnitude of turning behavior is altered."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042137", "l": "sequestering of neurotransmitter", "d": ["The process of binding or confining a neurotransmitter such that it is separated from other components of a biological system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0006528", "l": "asparagine metabolic process", "d": ["The chemical reactions and pathways involving asparagine, 2-amino-3-carbamoylpropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010376", "l": "stomatal complex formation", "d": ["The process that gives rise to the stomatal complex. This process pertains to the initial formation of a structure from unspecified parts. The stomatal complex is the stomatal guard cells and their associated epidermal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "74.233323709485049", "identifiers": [{"i": "GO:1903313", "l": "positive regulation of mRNA metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070804", "l": "positive regulation of metula development", "d": ["Any process that activates or increases the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030577", "l": "Lands organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Lands, a class of nuclear body that react against SP140 auto-antibodies."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006910", "l": "phagocytosis, recognition", "d": ["The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0008295", "l": "spermidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.062480095235458", "identifiers": [{"i": "GO:0007272", "l": "ensheathment of neurons", "d": ["The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042682", "l": "regulation of compound eye cone cell fate specification", "d": ["Any process that mediates the specification of a cell into a compound eye cone cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097241", "l": "hematopoietic stem cell migration to bone marrow", "d": ["The orderly movement of a hematopoietic stem cell into the bone marrow, and its subsequent positioning within defined functional compartments in that microenvironment. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903857", "l": "negative regulation of cytokinin dehydrogenase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cytokinin dehydrogenase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003331", "l": "positive regulation of extracellular matrix constituent secretion", "d": ["Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0014862", "l": "regulation of skeletal muscle contraction by chemo-mechanical energy conversion", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle contraction by regulating force and velocity of shortening. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through formation of cross bridges. The shortening leads to reduction of length of muscle fiber and sarcomeres."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900442", "l": "positive regulation of filamentous growth of a population of unicellular organisms in response to neutral pH", "d": ["Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0043928", "l": "exonucleolytic catabolism of deadenylated mRNA", "d": ["The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 3'-poly(A) tail."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0018934", "l": "nitrilotriacetate metabolic process", "d": ["The chemical reactions and pathways involving nitrilotriacetate, an aminotricarboxylic acid that binds bivalent metal ions in a ratio of 1:1. As an important industrial chelating agent, NTA has been widely used for various radionuclide processing and decontamination procedures, such as textile, paper and pulp processing and water treatment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006530", "l": "asparagine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of asparagine, 2-amino-3-carbamoylpropanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0010452", "l": "histone H3-K36 methylation", "d": ["The modification of histone H3 by addition of one or more methyl groups to lysine at position 36 of the histone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009399", "l": "nitrogen fixation", "d": ["The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0070794", "l": "negative regulation of conidiophore development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0045739", "l": "positive regulation of DNA repair", "d": ["Any process that activates or increases the frequency, rate or extent of DNA repair."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052781", "l": "chitobiose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any chitobiose, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0048318", "l": "axial mesoderm development", "d": ["The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0016198", "l": "axon choice point recognition", "d": ["The recognition of molecules at a choice point by an axon growth cone; at a choice point the growth cone determines the direction of its future growth."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900299", "l": "positive regulation of hexasaccharide transport", "d": ["Any process that activates or increases the frequency, rate or extent of hexasaccharide transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0010088", "l": "phloem development", "d": ["The formation of the principal food-conducting tissue of a vascular plant."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042049", "l": "intracellular acyl-CoA homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of acyl-CoA within a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070162", "l": "adiponectin secretion", "d": ["The regulated release of adiponectin, a protein hormone, by adipose tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0031922", "l": "pyridoxamine transport", "d": ["The directed movement of pyridoxamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0071220", "l": "cellular response to bacterial lipoprotein", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018355", "l": "protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine", "d": ["The formation of a protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140921", "l": "negative regulation of thermomorphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of thermomorphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904221", "l": "negative regulation of serine C-palmitoyltransferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of serine C-palmitoyltransferase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018340", "l": "peptidyl-O-(sn-1-glycerophosphoryl)-L-serine biosynthetic process from peptidyl-serine", "d": ["The modification of peptidyl-serine to peptidyl-O-(sn-1-glycerophosphoryl)-L-serine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0150038", "l": "postsynaptic dense core vesicle exocytosis", "d": ["The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a postsynaptic dense core vesicle by fusion of the granule with the plasma membrane of the postsynapse in response to increased cytosolic calcium levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0043708", "l": "cell adhesion involved in biofilm formation", "d": ["The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006963", "l": "positive regulation of antibacterial peptide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate, or extent of antibacterial peptide biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0033598", "l": "mammary gland epithelial cell proliferation", "d": ["The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of a cell population. Mammary gland epithelial cells make up the covering of surfaces of the mammary gland. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904262", "l": "negative regulation of TORC1 signaling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "73.003741351937961", "identifiers": [{"i": "GO:0002824", "l": "positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "d": ["Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0170002", "l": "halotropism", "d": ["A sodium-specific negative tropism that is crucial for surviving and thriving under high salinity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0035036", "l": "sperm-egg recognition", "d": ["The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042120", "l": "alginic acid metabolic process", "d": ["The chemical reactions and pathways involving alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015985", "l": "energy coupled proton transport, down electrochemical gradient", "d": ["The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that provides energy for the synthesis of ATP or GTP."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019597", "l": "(R)-mandelate catabolic process to benzoate", "d": ["The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including benzoate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045772", "l": "positive regulation of autophagosome size", "d": ["Any process that increases autophagosome size."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007365", "l": "periodic partitioning", "d": ["The regionalization process that divides the spatial regions of an embryo into serially repeated regions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902231", "l": "positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage", "d": ["Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000595", "l": "regulation of optic nerve formation", "d": ["Any process that modulates the frequency, rate or extent of optic nerve formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071506", "l": "cellular response to mycophenolic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051638", "l": "barbed-end actin filament uncapping", "d": ["The removal of capping protein from the barbed (or plus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009831", "l": "plant-type cell wall modification involved in multidimensional cell growth", "d": ["The series of events that occur during cell growth that result in chemical or structural changes to existing cell walls of the type composed chiefly of cellulose and pectin. An example of this is found in Arabidopsis thaliana."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001195", "l": "maintenance of transcriptional fidelity during transcription elongation by RNA polymerase III", "d": ["Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from a RNA polymerase III promoter."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060936", "l": "cardiac fibroblast cell development", "d": ["The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:1900612", "l": "F-9775B metabolic process", "d": ["The chemical reactions and pathways involving F-9775B."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048540", "l": "bursa of Fabricius development", "d": ["The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051388", "l": "positive regulation of neurotrophin TRK receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062003", "l": "negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity", "d": ["Any process that decreases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0043435", "l": "response to corticotropin-releasing hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0008343", "l": "adult feeding behavior", "d": ["Feeding behavior in a fully developed and mature organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900307", "l": "negative regulation of maltoheptaose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose transport."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021625", "l": "oculomotor nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075320", "l": "negative regulation of ascus development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044072", "l": "negative regulation by symbiont of host cell cycle", "d": ["The process in which a symbiont organism stops, prevents or reduces the rate or extent of its host's progression through its cell cycle via direct interactions with the host cell macromolecular machinery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901211", "l": "negative regulation of cardiac chamber formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061188", "l": "negative regulation of rDNA heterochromatin formation", "d": ["Any process that decreases the rate, frequency, or extent of ribosomal DNA heterochromatin formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140967", "l": "manganese import into cell", "d": ["The directed movement of mangnanese ions from outside of a cell into a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904552", "l": "regulation of chemotaxis to arachidonic acid", "d": ["Any process that modulates the frequency, rate or extent of chemotaxis to arachidonic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034395", "l": "regulation of transcription from RNA polymerase II promoter in response to iron", "d": ["Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an iron stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904232", "l": "regulation of aconitate hydratase activity", "d": ["Any process that modulates the frequency, rate or extent of aconitate hydratase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.281967957033203", "identifiers": [{"i": "GO:0019054", "l": "modulation by virus of host cellular process", "d": ["The process in which a virus effects a change in the processes and activities of its host organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010130", "l": "anaerobic ethylbenzene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ethylbenzene, a benzene derivative with an ethyl group attached to the ring, which occurs in the absence of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019128", "l": "peptidyl-tryptophan racemization", "d": ["The racemization of peptidyl-tryptophan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903656", "l": "regulation of type IV pilus biogenesis", "d": ["Any process that modulates the frequency, rate or extent of type IV pilus biogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903266", "l": "regulation of ornithine catabolic process", "d": ["Any process that modulates the frequency, rate or extent of ornithine catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055025", "l": "positive regulation of cardiac muscle tissue development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0006904", "l": "vesicle docking involved in exocytosis", "d": ["The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002610", "l": "regulation of plasmacytoid dendritic cell antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904983", "l": "glycine import into mitochondrion", "d": ["The process in which glycine is transported from the cytosol into the mitochondrial matrix."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0042688", "l": "crystal cell differentiation", "d": ["The process in which a hemocyte precursor cell acquires the characteristics of a crystal cell, a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140270", "l": "gluconate import across plasma membrane", "d": ["The directed movement of gluconate from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0085033", "l": "induction by symbiont of host I-kappaB kinase/NF-kappaB cascade", "d": ["Any process that activates or increases the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072159", "l": "epithelial cell migration involved in proximal tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to proximal tubule morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0070788", "l": "conidiophore stalk development", "d": ["The process whose specific outcome is the progression of the conidiophore stalk over time, from its formation to the mature structure. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0006531", "l": "aspartate metabolic process", "d": ["The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010900", "l": "negative regulation of phosphatidylcholine catabolic process", "d": ["Any process that decreases the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0009082", "l": "branched-chain amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:1901388", "l": "regulation of transforming growth factor beta activation", "d": ["Any process that modulates the frequency, rate or extent of transforming growth factor beta activation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000290", "l": "regulation of myotome development", "d": ["Any process that modulates the frequency, rate or extent of myotome development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006855", "l": "xenobiotic transmembrane transport", "d": ["The process in which a xenobiotic, a compound foreign to the organim exposed to it, is transported across a membrane. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0031398", "l": "positive regulation of protein ubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042322", "l": "negative regulation of circadian sleep/wake cycle, REM sleep", "d": ["Any process that stops, prevents or reduces the duration or quality of rapid eye movement (REM) sleep."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110090", "l": "positive regulation of hippocampal neuron apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0140051", "l": "positive regulation of endocardial cushion to mesenchymal transition", "d": ["Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0031948", "l": "positive regulation of glucocorticoid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019687", "l": "pyruvate biosynthetic process from acetate", "d": ["The chemical reactions and pathways resulting in the formation of pyruvate from other compounds, including acetate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:1900878", "l": "(Z)-nonadeca-1,14-diene metabolic process", "d": ["The chemical reactions and pathways involving (Z)-nonadeca-1,14-diene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.666259479937736", "identifiers": [{"i": "GO:0022411", "l": "cellular component disassembly", "d": ["A cellular process that results in the breakdown of a cellular component."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:1900430", "l": "positive regulation of filamentous growth of a population of unicellular organisms", "d": ["Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0075520", "l": "actin-dependent intracellular transport of virus", "d": ["The directed movement of a virus, or part of a virus, within the host cell cytoplasm via the host's actin filaments. Actin-dependent transport is induced by viral proteins that interact with actin and/or host cell motor proteins like myosins or that promotes actin polymerization/depolymerization reactions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021994", "l": "progression of neural tube closure", "d": ["The process in which the neural folds are fused extending from the initial closure points."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061729", "l": "GDP-mannose biosynthetic process from fructose-6-phosphate", "d": ["The chemical reactions and pathways resulting in the formation of GDP-mannose from fructose-6-phosphate."]}, {"i": "REACT:R-HSA-446205", "l": "Synthesis of GDP-mannose (Homo sapiens)", "d": []}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0051728", "l": "cell cycle switching, mitotic to meiotic cell cycle", "d": ["The process in which a cell switches cell cycle mode from mitotic to meiotic division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0002870", "l": "T cell anergy", "d": ["Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0050822", "l": "peptide stabilization", "d": ["Any process involved in maintaining the structure and integrity of a peptide and preventing it from being degraded."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990557", "l": "mitochondrial sulfate transmembrane transport", "d": ["The process in which sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0036295", "l": "cellular response to increased oxygen levels", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051560", "l": "mitochondrial calcium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051520", "l": "termination of bipolar cell growth", "d": ["Any process that stops the active process of bipolar cell growth, polarized growth from both ends of a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021803", "l": "extension of leading cell process to pial surface", "d": ["The extension of a long process to the pial surface as a cell leaves the ventricular zone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0046663", "l": "dorsal closure, leading edge cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a leading edge cell, the dorsal-most cells of the epidermis that migrates during dorsal closure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0052053", "l": "negative regulation by symbiont of host catalytic activity", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0070424", "l": "regulation of nucleotide-binding oligomerization domain containing signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of a nucleotide-binding oligomerization domain containing (NOD) pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090714", "l": "innate immunity memory response", "d": ["An immune response mediated by the innate immune system and directed against a previously encountered immunologic stimulus, being quicker and quantitatively better compared with the initial response to that stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0045879", "l": "negative regulation of smoothened signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0090134", "l": "cell migration involved in mesendoderm migration", "d": ["The orderly movement of epithelial cells from one site to another that contributes to the migration of mesendodermal tissue."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036172", "l": "thiamine salvage", "d": ["A process that generates thiamine (vitamin B1) from derivatives of it without de novo synthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905505", "l": "positive regulation of motile cilium assembly", "d": ["Any process that activates or increases the frequency, rate or extent of motile cilium assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0034286", "l": "response to maltose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009708", "l": "benzyl isoquinoline alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings."]}]}
{"type": "biolink:BiologicalProcess", "ic": "47.878630582770597", "identifiers": [{"i": "GO:0099537", "l": "trans-synaptic signaling", "d": ["Cell-cell signaling in either direction across the synaptic cleft."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106395", "l": "positive regulation of palmitic acid catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of a palmitic acid catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050841", "l": "peptidyl-N6,N6,N6-trimethyl-lysine hydroxylation to peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine", "d": ["The hydroxylation of peptidyl-N6,N6,N6-trimethyl-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106387", "l": "'de novo' GMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of guanosine 5'-monophosphate (GMP) through an inosine 5'-monophosphate (IMP) intermediate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110015", "l": "positive regulation of elastin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090470", "l": "shoot organ boundary specification", "d": ["The process in which the basal boundary between the stem and both vegetative and reproductive organs are established and maintained."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904573", "l": "regulation of selenocysteine insertion sequence binding", "d": ["Any process that modulates the frequency, rate or extent of selenocysteine insertion sequence binding."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900996", "l": "benzene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of benzene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.916538309327947", "identifiers": [{"i": "GO:0032069", "l": "regulation of nuclease activity", "d": ["Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001921", "l": "positive regulation of receptor recycling", "d": ["Any process that activates or increases the frequency, rate or extent of receptor recycling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0099151", "l": "regulation of postsynaptic density assembly", "d": ["Any process that modulates the frequency, rate or extent of postsynaptic density assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic density."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051893", "l": "regulation of focal adhesion assembly", "d": ["Any process that modulates the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019625", "l": "atrazine catabolic process to cyanuric acid", "d": ["The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into cyanuric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0001550", "l": "ovarian cumulus expansion", "d": ["Increase in size of the cumulus surrounding the oocyte including change in morphology due to proliferation and dispersion of cumulus cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098545", "l": "maintenance of protein complex location in cytoplasm", "d": ["Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000244", "l": "regulation of FtsZ-dependent cytokinesis", "d": ["Any process that modulates the frequency, rate or extent of FtsZ-dependent cytokinesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0099022", "l": "vesicle tethering", "d": ["The initial, indirect interaction between a vesicle membrane and a membrane to which it is targeted for fusion. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to interaction between factors involved in fusion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.054311793581761", "identifiers": [{"i": "GO:0022616", "l": "DNA strand elongation", "d": ["The DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900219", "l": "positive regulation of apoptotic process involved in metanephric nephron tubule development", "d": ["Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0045013", "l": "carbon catabolite repression of transcription", "d": ["A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:2001234", "l": "negative regulation of apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032213", "l": "regulation of telomere maintenance via semi-conservative replication", "d": ["Any process that modulates the frequency, rate or extent of the semi-conservative replication of telomeric DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019690", "l": "pyrimidine deoxyribonucleoside interconversion", "d": ["The chemical reactions and pathways by which a pyrimidine deoxyribonucleoside is synthesized from another deoxyribopyrimidine nucleoside."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018245", "l": "protein O-linked glycosylation via tyrosine", "d": ["The glycosylation of protein via the O4' atom of peptidyl-tyrosine, O4'-glycosyl-L-tyrosine; the carbohydrate is glucose, the origin for glycogen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014732", "l": "skeletal muscle atrophy", "d": ["A process, occurring in skeletal muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904838", "l": "regulation of male germ-line stem cell asymmetric division", "d": ["Any process that modulates the frequency, rate or extent of male germ-line stem cell asymmetric division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.843050782660015", "identifiers": [{"i": "GO:0060193", "l": "positive regulation of lipase activity", "d": ["Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061482", "l": "response to irinotecan", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an irinotecan stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0016237", "l": "lysosomal microautophagy", "d": ["The transfer of cytosolic components into the lysosomal compartment by direct invagination of the lysosomal membrane without prior sequestration into an autophagosome. The engulfing membranes fuse, resulting in the lysosomal delivery of the cargo wrapped in a single membrane derived from the invaginated lysosomal membrane. In S. cerevisiae, the vacuole is the lysosomal compartment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900437", "l": "regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus", "d": ["Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071360", "l": "cellular response to exogenous dsRNA", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1902523", "l": "positive regulation of protein K63-linked ubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein K63-linked ubiquitination."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.264511229695032", "identifiers": [{"i": "GO:0007531", "l": "mating type determination", "d": ["Any process that establishes and transmits the specification of mating type upon an individual. Mating types are the equivalent in microorganisms of the sexes in higher organisms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0097497", "l": "blood vessel endothelial cell delamination", "d": ["The process of negative regulation of cell adhesion that results in blood vessel endothelial cells splitting off from an existing endothelial sheet."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904684", "l": "negative regulation of metalloendopeptidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0070230", "l": "positive regulation of lymphocyte apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0010042", "l": "response to manganese ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900346", "l": "negative regulation of methane biosynthetic process from methanethiol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methanethiol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0075202", "l": "regulation of penetration hypha formation", "d": ["Any process that modulates the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061319", "l": "nephrocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006799", "l": "polyphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006967", "l": "positive regulation of antifungal peptide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate, or extent of antifungal peptide biosynthesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0042976", "l": "activation of Janus kinase activity", "d": ["The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:2000100", "l": "regulation of establishment or maintenance of bipolar cell polarity regulating cell shape", "d": ["Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061910", "l": "autophagosome-endosome fusion", "d": ["The process in which an autophagosome fuses with an endosome to create an intermediate autophagic organelle called amphisome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021628", "l": "olfactory nerve formation", "d": ["The process that gives rise to the olfactory nerve. This process pertains to the initial formation of a structure from unspecified parts. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0014052", "l": "regulation of gamma-aminobutyric acid secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0072742", "l": "SAGA complex localization to transcription regulatory region", "d": ["Any process in which a SAGA complex is transported to, or maintained in, a specific location in the transcription regulatory region of a gene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035181", "l": "larval burrowing behavior", "d": ["Digging into the substrate by non-feeding larvae in search for food-free sites suitable for pupation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046892", "l": "peptidyl-S-carbamoyl-L-cysteine dehydration", "d": ["The dehydration of peptidyl-S-carbamoyl-L-cysteine to form peptidyl-S-cyano-L-cysteine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009789", "l": "positive regulation of abscisic acid-activated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of abscisic acid (ABA) signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0051685", "l": "maintenance of ER location", "d": ["Any process in which the endoplasmic reticulum is maintained in a specific location within a cell and prevented from moving elsewhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "54.460484309878169", "identifiers": [{"i": "GO:0042886", "l": "amide transport", "d": ["The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021947", "l": "outward migration of deep nuclear neurons", "d": ["The directed movement of a deep nuclear neuron from their ventrolateral origin to a rostrodorsal region of the cerebellar plate."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032064", "l": "positive regulation of translational initiation in response to osmotic stress", "d": ["Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039652", "l": "induction by virus of host NF-kappaB cascade", "d": ["Any process in which a virus starts, promotes, or enhances a host NF-kappaB cascade."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0099011", "l": "neuronal dense core vesicle exocytosis", "d": ["The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a neuronal dense core vesicle by fusion of the granule with the plasma membrane of a neuron in response to increased cytosolic calcium levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0036120", "l": "cellular response to platelet-derived growth factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030724", "l": "testicular fusome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of testicular cells, an organelle derived from the spectrosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007146", "l": "meiotic recombination nodule assembly", "d": ["During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090388", "l": "phagosome-lysosome docking involved in apoptotic cell clearance", "d": ["The initial attachment of a phagosome membrane to a lysosome membrane that occurs as a part of apoptotic cell clearance. Docking requires only that the proteins come close enough to interact and adhere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0060607", "l": "cell-cell adhesion involved in sealing an epithelial fold", "d": ["The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of an epithelial tube."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0009151", "l": "purine deoxyribonucleotide metabolic process", "d": ["The chemical reactions and pathways involving purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "63.158834410454425", "identifiers": [{"i": "GO:0009117", "l": "nucleotide metabolic process", "d": ["The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0060828", "l": "regulation of canonical Wnt signaling pathway", "d": ["Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009788", "l": "negative regulation of abscisic acid-activated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0016191", "l": "synaptic vesicle uncoating", "d": ["The removal of the protein coat on a synaptic vesicle following the pinching step at the end of budding from the presynaptic membrane."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:0021952", "l": "central nervous system projection neuron axonogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903621", "l": "protein localization to photoreceptor connecting cilium", "d": ["A process in which a protein is transported to, or maintained in, a location within a photoreceptor connecting cilium."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1900734", "l": "positive regulation of polyketide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of polyketide biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0045821", "l": "positive regulation of glycolytic process", "d": ["Any process that activates or increases the frequency, rate or extent of glycolysis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "46.082077836056463", "identifiers": [{"i": "GO:0007267", "l": "cell-cell signaling", "d": ["Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021959", "l": "cuneatus tract morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the cuneatus tract, a group of axons that are from neurons involved in proprioception from the upper trunk and upper limb."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0010833", "l": "telomere maintenance via telomere lengthening", "d": ["Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "71.685364931984026", "identifiers": [{"i": "GO:0006576", "l": "biogenic amine metabolic process", "d": ["The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061683", "l": "branching involved in seminal vesicle morphogenesis", "d": ["The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0002381", "l": "immunoglobulin production involved in immunoglobulin-mediated immune response", "d": ["The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034079", "l": "butanediol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:1902426", "l": "deactivation of mitotic spindle assembly checkpoint", "d": ["A positive regulation of the mitotic metaphase/anaphase transition that results from deactivation of the mitotic spindle assembly checkpoint."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070327", "l": "thyroid hormone transport", "d": ["The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902447", "l": "negative regulation of shade avoidance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of shade avoidance."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0018142", "l": "protein-DNA covalent cross-linking", "d": ["The formation of a covalent cross-link between DNA and a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050434", "l": "positive regulation of viral transcription", "d": ["Any process that activates or increases the frequency, rate or extent of viral transcription."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902488", "l": "cholangiocyte apoptotic process", "d": ["Any apoptotic process in a cholangiocyte."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046657", "l": "folic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of folic acid, pteroylglutamic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0060494", "l": "inductive mesenchymal-endodermal cell signaling", "d": ["Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell changing the fate of the endodermal cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.56681308101922", "identifiers": [{"i": "GO:0045088", "l": "regulation of innate immune response", "d": ["Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0061259", "l": "mesonephric glomerular mesangial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "77.481603666032214", "identifiers": [{"i": "GO:1901336", "l": "lactone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lactone."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046298", "l": "2,4-dichlorobenzoate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0003232", "l": "bulbus arteriosus development", "d": ["The process whose specific outcome is the progression of the bulbus arteriosus over time, from its formation to the mature structure. The bulbus arteriosus is an elastic heart chamber."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0042542", "l": "response to hydrogen peroxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0015824", "l": "proline transport", "d": ["The directed movement of proline, pyrrolidine-2-carboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0075732", "l": "viral penetration into host nucleus", "d": ["The crossing by the virus of the host nuclear membrane, either as naked viral genome or for small viruses as an intact capsid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000852", "l": "regulation of corticosterone secretion", "d": ["Any process that modulates the frequency, rate or extent of corticosterone secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002022", "l": "detection of dietary excess", "d": ["The neurological process in which the brain senses excessive caloric intake."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0032481", "l": "positive regulation of type I interferon production", "d": ["Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0030490", "l": "maturation of SSU-rRNA", "d": ["Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:0030901", "l": "midbrain development", "d": ["The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010585", "l": "glutamine secretion", "d": ["The controlled release of glutamine by a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045200", "l": "establishment of neuroblast polarity", "d": ["The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.958976004066542", "identifiers": [{"i": "GO:1904035", "l": "regulation of epithelial cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039680", "l": "actin-dependent intracellular transport of virus towards nucleus", "d": ["The directed movement of a virus, or part of a virus, towards the host cell nucleus using actin filaments."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1904596", "l": "regulation of connective tissue replacement involved in inflammatory response wound healing", "d": ["Any process that modulates the frequency, rate or extent of wound healing connective tissue replacement, which may be replaced with fibrotic material, that occurs as part of an inflammatory response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0048852", "l": "diencephalon morphogenesis", "d": ["The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0099403", "l": "maintenance of mitotic sister chromatid cohesion, telomeric", "d": ["The process in which the association between sister chromatids of a replicated chromosome along the length of the telomeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046512", "l": "sphingosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034376", "l": "conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle", "d": ["The process in which a discoidal high-density lipoprotein (HDL) particle acquires additional lipid or protein molecules, and cholesterol in the particle is converted to tightly bound cholesterol esters by the action of phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT), resulting in the formation of a spherical HDL particle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010268", "l": "brassinosteroid homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of brassinosteroids within an organism or cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010072", "l": "primary shoot apical meristem specification", "d": ["The specification of the meristem which will give rise to all post-embryonic above-ground structures of the plant as well as the non-root below-ground structures, such as rhizomes and tubers."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902798", "l": "positive regulation of snoRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of snoRNA processing."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034965", "l": "intronic box C/D RNA processing", "d": ["Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box C/D snoRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:1903019", "l": "negative regulation of glycoprotein metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904534", "l": "negative regulation of telomeric loop disassembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop disassembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "52.278733901265547", "identifiers": [{"i": "GO:0010817", "l": "regulation of hormone levels", "d": ["Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0006569", "l": "tryptophan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072200", "l": "negative regulation of mesenchymal cell proliferation involved in ureter development", "d": ["Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019939", "l": "peptidyl-S-palmitoleyl-L-cysteine biosynthetic process from peptidyl-cysteine", "d": ["The modification of peptidyl-cysteine to form peptidyl-S-palmitoleyl-L-cysteine specifically."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044864", "l": "positive regulation by virus of host cell division", "d": ["Any process where an infecting virus activates or increases the frequency, rate or extent of its host's cell division."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904460", "l": "positive regulation of substance P secretion", "d": ["Any process that activates or increases the frequency, rate or extent of substance P secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.622337805354121", "identifiers": [{"i": "GO:0040017", "l": "positive regulation of locomotion", "d": ["Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:1902291", "l": "cell cycle DNA replication DNA ligation", "d": ["Any DNA ligation that is involved in cell cycle DNA replication."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032294", "l": "peripheral nervous system non-myelinated axon ensheathment", "d": ["The process in which a non-myelinating Schwann cell membrane encircles an axon in the peripheral nervous system. A single non-myelinating Schwann cell will typically associate with multiple axons."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0036394", "l": "amylase secretion", "d": ["The controlled release of amylase from a cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032938", "l": "negative regulation of translation in response to oxidative stress", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033022", "l": "cyclopentanol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cyclopentanol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2001006", "l": "regulation of cellulose biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of cellulose biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "61.486500217525411", "identifiers": [{"i": "GO:0002697", "l": "regulation of immune effector process", "d": ["Any process that modulates the frequency, rate, or extent of an immune effector process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0039011", "l": "pronephric proximal tubule morphogenesis", "d": ["The process in which the anatomical structures of a pronephric nephron proximal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039699", "l": "viral mRNA cap methylation", "d": ["An innate immune response evasion mechanism in which a virus methylates the 2'-O-ribose of the first or second transcribed nucleotide of its mRNAs. Methylation allows evasion of the host innate immune response, which degrades cap0 (non-methylated) mRNAs."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009849", "l": "tryptophan-independent indoleacetic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of indoleacetic acid, independent of tryptophan."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901099", "l": "negative regulation of signal transduction in absence of ligand", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction in absence of ligand."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046089", "l": "cytosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:2000318", "l": "positive regulation of T-helper 17 type immune response", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0090214", "l": "spongiotrophoblast layer developmental growth", "d": ["The increase in size or mass of the spongiotrophoblast layer of the placenta where the increase in size or mass contributes to the progression of that layer over time from its formation to its mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0090644", "l": "age-related resistance", "d": ["An innate immune response that is positively correlated with host plant development. As a plant develops, its innate resistance to pathogenic infections increases. The mechanisms involved in age-related resistance differ in nature or in aspects of regulation from the hypersensitive response (HR), systemic acquired resistance (SAR), or induced systemic resistance (ISR)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0048205", "l": "COPI coating of Golgi vesicle", "d": ["The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903611", "l": "negative regulation of calcium-dependent ATPase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium-dependent ATPase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1903225", "l": "negative regulation of endodermal cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0099116", "l": "tRNA 5'-end processing", "d": ["The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0043416", "l": "regulation of skeletal muscle tissue regeneration", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "57.758956090052671", "identifiers": [{"i": "GO:1903046", "l": "meiotic cell cycle process", "d": ["A process that is part of the meiotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990401", "l": "embryonic lung development", "d": ["The process occurring during the embryonic phase whose specific outcome is the progression of the lung over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021974", "l": "trigeminothalamic tract morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the trigeminothalamic tract, one of the major routes of nociceptive and temperature signaling from the face."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0007527", "l": "adult somatic muscle development", "d": ["The process whose specific outcome is the progression of the adult somatic muscle over time, from its formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0042930", "l": "enterobactin transport", "d": ["The directed movement of the siderochrome enterobactin, a cyclic trimer of 2, 3 dihydroxybenzoylserine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000093", "l": "regulation of mesonephric nephron tubule epithelial cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0010275", "l": "NAD(P)H dehydrogenase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form NAD(P)H dehydrogenase complex, which is involved in electron transport from an unidentified electron donor, possibly NAD(P)H or ferredoxin(Fd) to the plastoquinone pool."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000789", "l": "positive regulation of venous endothelial cell fate commitment", "d": ["Any process that activates or increases the frequency, rate or extent of venous endothelial cell fate commitment."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901766", "l": "phosphinothricin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphinothricin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904119", "l": "negative regulation of otic vesicle morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016092", "l": "prenol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0002469", "l": "myeloid dendritic cell antigen processing and presentation", "d": ["The process in which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0006447", "l": "regulation of translational initiation by iron", "d": ["Any process that modulates the frequency, rate or extent of the translation of certain mRNAs involved in iron metabolism; regulated by the concentration of iron."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0035568", "l": "N-terminal peptidyl-proline methylation", "d": ["The methylation of the N-terminal proline of proteins."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099557", "l": "trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, mediated by transynaptic protein complexes, that modulates the synaptic transmission properties of the synapse."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905908", "l": "positive regulation of amyloid fibril formation", "d": ["Any process that activates or increases the frequency, rate or extent of amyloid fibril formation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:1900120", "l": "regulation of receptor binding", "d": ["Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990937", "l": "xylan acetylation", "d": ["The addition of one or more acetyl groups to a xylan molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0097264", "l": "self proteolysis", "d": ["The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010236", "l": "plastoquinone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of plastoquinone, a lipid-soluble electron-transporting coenzyme present in the chloroplast."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.701260003289605", "identifiers": [{"i": "GO:0016573", "l": "histone acetylation", "d": ["The modification of a histone by the addition of an acetyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0016136", "l": "saponin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106136", "l": "lectin-induced modified bacterial internalization", "d": ["The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by secretion of lectins which bind to the bacterial surface. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "65.805366613539277", "identifiers": [{"i": "GO:0046488", "l": "phosphatidylinositol metabolic process", "d": ["The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904413", "l": "negative regulation of cardiac ventricle development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "89.344352379398387", "identifiers": [{"i": "GO:0046477", "l": "glycosylceramide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045342", "l": "MHC class II biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of major histocompatibility protein class II."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060366", "l": "lambdoid suture morphogenesis", "d": ["The process in which the lambdoid suture is generated and organized."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0098035", "l": "viral DNA genome packaging via site-specific sequence recognition", "d": ["The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites by a viral terminase."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0010075", "l": "regulation of meristem growth", "d": ["Any process involved in maintaining the size and shape of a meristem."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0007079", "l": "mitotic chromosome movement towards spindle pole", "d": ["The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0032639", "l": "TRAIL production", "d": ["The appearance of TRAIL due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0031125", "l": "rRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of an rRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0017196", "l": "N-terminal peptidyl-methionine acetylation", "d": ["The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990983", "l": "tRNA demethylation", "d": ["The removal of a methyl group from one or more residues within a tRNA molecule."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032193", "l": "ubiquinone biosynthetic process via 2-polyprenylphenol", "d": ["The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 2-polyprenylphenol and 2-polyprenyl-6-hydroxyphenol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "68.819490397197882", "identifiers": [{"i": "GO:0040029", "l": "epigenetic regulation of gene expression", "d": ["A process that modulates the frequency, rate or extent of gene expression through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine methylation of DNA. Once established, this regulation may be maintained over many cell divisions. It can also be heritable in the absence of the instigating signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034496", "l": "multivesicular body membrane disassembly", "d": ["The controlled breakdown of the membranes of multivesicular bodies."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.535054500181104", "identifiers": [{"i": "GO:0070601", "l": "centromeric sister chromatid cohesion", "d": ["The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the centromeric region of the chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905266", "l": "blasticidin S biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of blasticidin S."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009159", "l": "deoxyribonucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0030651", "l": "peptide antibiotic biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of peptides with antibiotic activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904278", "l": "positive regulation of wax biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of wax biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072705", "l": "cellular response to mercaptoethanol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0071292", "l": "cellular response to silver ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0061042", "l": "vascular wound healing", "d": ["Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062228", "l": "negative regulation of adult somatic muscle development", "d": ["Any process that decreases the rate, frequency or extent of adult somatic muscle development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0090133", "l": "mesendoderm migration", "d": ["The process in which the population of cells that make up a mesendoderm undergo directed movement. The mesendoderm is the epithelial tissue that gives rise to both mesoderm and endoderm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "64.35073291073661", "identifiers": [{"i": "GO:0104004", "l": "cellular response to environmental stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0009191", "l": "ribonucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0033635", "l": "modulation by symbiont of host response to abiotic stimulus", "d": ["Any process in which an organism modulates a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0045590", "l": "negative regulation of regulatory T cell differentiation", "d": ["Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1903871", "l": "DNA recombinase mediator complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a DNA recombinase mediator complex."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905165", "l": "regulation of lysosomal protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072248", "l": "metanephric podocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "70.356779217613806", "identifiers": [{"i": "GO:1903311", "l": "regulation of mRNA metabolic process", "d": ["Any process that modulates the frequency, rate or extent of mRNA metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "69.000891501185137", "identifiers": [{"i": "GO:0030335", "l": "positive regulation of cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of cell migration."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000237", "l": "leptotene", "d": ["The cell cycle phase which is the first stage of prophase I in meiosis, and during which the chromosomes first become visible."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019624", "l": "atrazine catabolic process to isopropylamine", "d": ["The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into isopropylamine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046774", "l": "suppression by virus of host intracellular interferon activity", "d": ["Any viral process that results in the inhibition of interferon activity within the host cell."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0051760", "l": "meiotic sister chromatid cohesion, arms", "d": ["The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during meiosis."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002609", "l": "positive regulation of myeloid dendritic cell antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0010463", "l": "mesenchymal cell proliferation", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0062022", "l": "mitotic cohesin ssDNA (lagging strand) loading", "d": ["The ATP-dependent protein localization to chromatin by which a cohesin ring complex is topologically linked to ssDNA (lagging strand) which is already linked to a dsDNA (leading strand) molecule as part of the mitotic cell cycle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0120262", "l": "negative regulation of heterochromatin organization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin organization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071645", "l": "positive regulation of chemokine (C-C motif) ligand 4 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044522", "l": "envenomation resulting in myocyte killing in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, killing heart myocytes and ultimately resulting in muscle damage in the bitten organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.527524213458875", "identifiers": [{"i": "GO:0045762", "l": "positive regulation of adenylate cyclase activity", "d": ["Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "79.240751554780076", "identifiers": [{"i": "GO:0001677", "l": "formation of translation initiation ternary complex", "d": ["Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0019659", "l": "glucose catabolic process to lactate", "d": ["The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, and possibly ethanol, yielding energy in the form of adenosine triphosphate (ATP)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990767", "l": "prostaglandin receptor internalization", "d": ["The process that results in the uptake of a prostaglandin receptor into an endocytic vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1901166", "l": "neural crest cell migration involved in autonomic nervous system development", "d": ["Any neural crest cell migration that is involved in autonomic nervous system development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046754", "l": "viral exocytosis", "d": ["The exit of a fully formed virion particles from the host cell by exocytosis via a host vesicle."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090475", "l": "lys-lys specific dibasic protein processing", "d": ["Any protein processing achieved by the cleavage of a peptide bond after two consecutive lysine amino acid residues within a protein."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000430", "l": "positive regulation of neutrophil aggregation", "d": ["Any process that activates or increases the frequency, rate or extent of neutrophil aggregation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901414", "l": "negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "76.652932776586212", "identifiers": [{"i": "GO:0035114", "l": "imaginal disc-derived appendage morphogenesis", "d": ["The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904916", "l": "transmembrane L-lysine transport from lysosomal lumen to cytosol", "d": ["The directed movement of L-lysine from the lysosomal lumen across the lysosomal membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:0032462", "l": "regulation of protein homooligomerization", "d": ["Any process that modulates the frequency, rate or extent of protein homooligomerization."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903386", "l": "negative regulation of homophilic cell adhesion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of homophilic cell adhesion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0006546", "l": "glycine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycine, aminoethanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:2000195", "l": "negative regulation of female gonad development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070606", "l": "regulation of (1->3)-alpha-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0007296", "l": "vitellogenesis", "d": ["The production of yolk. Yolk is a mixture of materials used for embryonic nutrition."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903220", "l": "positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity", "d": ["Any process that activates or increases the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018909", "l": "dodecyl sulfate metabolic process", "d": ["The chemical reactions and pathways involving dodecyl sulfate, commonly found as sodium dodecyl sulfate (SDS), a component of a variety of synthetic surfactants."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0033153", "l": "T cell receptor V(D)J recombination", "d": ["The process in which T cell receptor V, D, and J, or V and J gene segments, depending on the specific locus, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS)."]}]}
{"type": "biolink:BiologicalProcess", "ic": "78.688704758796746", "identifiers": [{"i": "GO:0006544", "l": "glycine metabolic process", "d": ["The chemical reactions and pathways involving glycine, aminoethanoic acid."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:0015012", "l": "heparan sulfate proteoglycan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900907", "l": "positive regulation of hexadecanal metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of hexadecanal metabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900875", "l": "heptadec-1-ene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heptadec-1-ene."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106305", "l": "mannogen catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018316", "l": "peptide cross-linking via L-cystine", "d": ["The oxidation of two peptidyl-cysteine residues to form a peptidyl-L-cystine (dicysteine) in which segments of peptide chain are linked by a disulfide bond; the cross-link may be between different or the same peptide chain."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000907", "l": "negative regulation of glucomannan catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucomannan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009447", "l": "putrescine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of putrescine, 1,4-diaminobutane; putrescine is the metabolic precursor of spermidine and spermine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0140667", "l": "regulation of oxytocin production", "d": ["Any process that modulates the frequency, rate, or extent of production of oxytocin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "49.840734471723565", "identifiers": [{"i": "GO:0044419", "l": "biological process involved in interspecies interaction between organisms", "d": ["Any process evolved to enable an interaction with an organism of a different species."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.018172800177666", "identifiers": [{"i": "GO:0034312", "l": "diol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.242070417869868", "identifiers": [{"i": "GO:1900732", "l": "regulation of polyketide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of polyketide biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "56.760847922943938", "identifiers": [{"i": "GO:0001816", "l": "cytokine production", "d": ["The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0032205", "l": "negative regulation of telomere maintenance", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061258", "l": "mesonephric podocyte cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1904896", "l": "ESCRT complex disassembly", "d": ["The disaggregation of an ESCRT complex into its constituent components."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0002649", "l": "regulation of tolerance induction to self antigen", "d": ["Any process that modulates the frequency, rate, or extent of tolerance induction to self antigen."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1900153", "l": "positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "d": ["Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1905295", "l": "regulation of neural crest cell fate specification", "d": ["Any process that modulates the frequency, rate or extent of neural crest cell fate specification."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1902244", "l": "cis-abienol metabolic process", "d": ["The chemical reactions and pathways involving cis-abienol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "81.643449434865403", "identifiers": [{"i": "GO:0019585", "l": "glucuronate metabolic process", "d": ["The chemical reactions and pathways involving glucuronate, any salt or ester of glucuronic acid, the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141033", "l": "perturbation by symbiont of host actin cytoskeleton via actin polymerization", "d": ["The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by polymerizing the host filamentous actin. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902997", "l": "negative regulation of neurofibrillary tangle assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neurofibrillary tangle assembly."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:0034014", "l": "response to triglyceride", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070347", "l": "regulation of brown fat cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of brown fat cell proliferation."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0006031", "l": "chitin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904846", "l": "negative regulation of establishment of bipolar cell polarity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of bipolar cell polarity."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002242", "l": "defense response to parasitic plant", "d": ["Reactions triggered in response to the presence of a parasitic plant that act to protect an organism."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071416", "l": "cellular response to tropane", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine."]}]}
{"type": "biolink:BiologicalProcess", "ic": "85.452777855834967", "identifiers": [{"i": "GO:0097187", "l": "dentinogenesis", "d": ["The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071303", "l": "cellular response to vitamin B3", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110094", "l": "polyphosphate-mediated signaling", "d": ["Any process that mediates the transfer of information from one cell to another using polyphosphate as the signal."]}]}
{"type": "biolink:BiologicalProcess", "ic": "67.235616146829116", "identifiers": [{"i": "GO:0042633", "l": "hair cycle", "d": ["The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0048655", "l": "anther wall tapetum morphogenesis", "d": ["The process in which the anatomical structures of the anther wall tapetum are generated and organized. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904466", "l": "positive regulation of matrix metallopeptidase secretion", "d": ["Any process that activates or increases the frequency, rate or extent of matrix metallopeptidase secretion."]}]}
{"type": "biolink:BiologicalProcess", "ic": "75.253913141376358", "identifiers": [{"i": "GO:0045216", "l": "cell-cell junction organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0070879", "l": "fungal-type cell wall beta-glucan metabolic process", "d": ["The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0072062", "l": "proximal convoluted tubule segment 1 cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the S1 cells of the kidney as it progresses from its formation to the mature state."]}]}
{"type": "biolink:BiologicalProcess", "ic": "82.070741307315856", "identifiers": [{"i": "GO:0034508", "l": "centromere complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900994", "l": "(-)-secologanin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (-)-secologanin."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032497", "l": "detection of lipopolysaccharide", "d": ["The series of events in which a lipopolysaccharide stimulus is received by a cell and converted into a molecular signal. Lipopolysaccharide is a major component of the cell wall of gram-negative bacteria."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.755214738114731", "identifiers": [{"i": "GO:0006658", "l": "phosphatidylserine metabolic process", "d": ["The chemical reactions and pathways involving phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. They are important constituents of cell membranes."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003142", "l": "cardiogenic plate morphogenesis", "d": ["The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0015838", "l": "amino-acid betaine transport", "d": ["The directed movement of betaine, the N-trimethyl derivative of an amino acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]}
{"type": "biolink:BiologicalProcess", "ic": "87.116661854742532", "identifiers": [{"i": "GO:1902093", "l": "positive regulation of flagellated sperm motility", "d": ["Any process that activates or increases the frequency, rate or extent of flagellated sperm motility."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0070203", "l": "regulation of establishment of protein localization to telomere", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the telomeric region of a chromosome."]}]}
{"type": "biolink:BiologicalProcess", "ic": "88.137251286633841", "identifiers": [{"i": "GO:2000194", "l": "regulation of female gonad development", "d": ["Any process that modulates the frequency, rate or extent of female gonad development."]}]}
{"type": "biolink:BiologicalProcess", "ic": "80.50567595061159", "identifiers": [{"i": "GO:0001961", "l": "positive regulation of cytokine-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061079", "l": "left horn of sinus venosus development", "d": ["The progression of the left horn of the sinus venosus from its initial formation to the mature structure."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098865", "l": "disruption by symbiont of host tight cell-cell junction", "d": ["The disruption of host host tight cell-cell junctions, a cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other."]}]}
{"type": "biolink:BiologicalProcess", "ic": "95.410862358716358", "identifiers": [{"i": "GO:1905807", "l": "negative regulation of synapse pruning", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000995", "l": "negative regulation of mannan catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mannan catabolic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "84.124192141464761", "identifiers": [{"i": "GO:0046824", "l": "positive regulation of nucleocytoplasmic transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0007147", "l": "female meiosis II", "d": ["The cell cycle process in which the second meiotic division occurs in the female germline."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:0098716", "l": "nickel cation import across plasma membrane", "d": ["The directed movement of nickel cations from outside of a cell, across the plasma membrane and into the cytosol."]}]}
{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009638", "l": "phototropism", "d": ["The movement of an organism, or part of an organism, in response to a light stimulus, usually toward or away from it."]}]}
{"type": "biolink:BiologicalProcess", "ic": "83.548113645350185", "identifiers": [{"i": "GO:0032109", "l": "positive regulation of response to nutrient levels", "d": ["Any process that activates or increases the frequency, rate or extent of a response to nutrient levels."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0140467", "l": "integrated stress response signaling", "d": ["The series of molecular signals generated in response to diverse stress stimuli required to restore cellular homeostasis. The core event in this pathway is the phosphorylation of eIF2 alpha by one of four members of the eIF2a kinase family (EIF2AK1/HRI, EIF2AK2/PKR, EIF2AK3/PERK and EIF2AK4/GCN2), which leads to a decrease in global protein synthesis and the induction of selected genes, including the transcription factor ATF4, that together promote cellular recovery."]}]}
{"type": "biolink:BiologicalProcess", "ic": "92.726388927917483", "identifiers": [{"i": "GO:1900974", "l": "regulation of tatiopterin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of tatiopterin biosynthetic process."]}]}
{"type": "biolink:BiologicalProcess", "ic": "86.232587076149059", "identifiers": [{"i": "GO:0045230", "l": "capsule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the capsule, a protective structure surrounding some species of bacteria and fungi."]}]}
{"type": "biolink:BiologicalProcess", "ic": "90.821724717432701", "identifiers": [{"i": "GO:0045625", "l": "regulation of T-helper 1 cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation."]}]}